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PMC:7324763 / 9374-11307 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T200 23-34 CL:0000542 denotes lymphocytes
T201 125-133 GO:0030674 denotes bridging
T202 138-144 GO:0045087 denotes innate
T203 153-161 GO:0002250 denotes adaptive
T204 162-168 GO:0002250;UBERON:0002405 denotes immune
T205 169-178 GO:0002250 denotes responses
T206 188-194 NCBITaxon:9606 denotes humans
T207 237-247 CL:0000080 denotes peripheral
T208 248-253 CL:0000080;UBERON:0000178 denotes blood
T209 254-264 CL:0000738 denotes leukocytes
T210 306-310 PR:000001889 denotes CD14
T211 312-316 PR:000001002 denotes CD19
T212 318-322 PR:000001024 denotes CD56
T213 324-328 PR:000001483 denotes CD16
T214 391-398 GO:0010467 denotes express
T215 439-447 GO:0065007 denotes regulate
T216 482-487 NCBITaxon:10239 denotes viral
T217 540-552 GO:0001906 denotes cell killing
T218 595-604 CHEBI:36357;CHEBI:36357 denotes molecules
T219 737-742 PR:000001895 denotes NKp30
T220 744-749 PR:000001894 denotes NKp44
T221 755-760 PR:000001893 denotes NKp46
T222 797-802 PR:000001828 denotes NKG2D
T223 855-861 PR:000001302 denotes DNAM-1
T224 939-953 GO:0019814 denotes Immunoglobulin
T225 1020-1024 PR:000001402 denotes CD94
T226 1025-1030 PR:000002023 denotes NKG2A
T227 1055-1062 CL:0000623;GO:0030101 denotes NK cell
T228 1063-1073 GO:0030101 denotes activation
T229 1108-1113 NCBITaxon:10239 denotes viral
T230 1156-1169 GO:0016020 denotes transmembrane
T231 1199-1204 NCBITaxon:10088 denotes mouse
T232 1219-1224 SP_6;NCBITaxon:9606 denotes human
T233 1225-1230 PR:000002024 denotes NKG2C
T234 1270-1275 NCBITaxon:10239 denotes virus
T235 1295-1299 PR:000001483 denotes CD16
T236 1309-1317 GO:0042571 denotes antibody
T237 1417-1428 NCBITaxon:10376 denotes herpesvirus
T238 1474-1483 GO:0065007 denotes modulated
T239 1628-1635 NCBITaxon:10239 denotes virally
T240 1664-1671 CHEBI:59132;CHEBI:59132 denotes antigen
T241 1699-1703 PR:000001379 denotes IL-2
T242 1751-1755 GO:0008283 denotes cell
T243 1916-1921 NCBITaxon:10239 denotes viral
T76113 23-34 CL:0000542 denotes lymphocytes
T19959 125-133 GO:0030674 denotes bridging
T89224 138-144 GO:0045087 denotes innate
T2115 153-161 GO:0002250 denotes adaptive
T8007 162-168 GO:0002250;UBERON:0002405 denotes immune
T44031 169-178 GO:0002250 denotes responses
T99975 188-194 NCBITaxon:9606 denotes humans
T68303 237-247 CL:0000080 denotes peripheral
T97120 248-253 CL:0000080;UBERON:0000178 denotes blood
T49734 254-264 CL:0000738 denotes leukocytes
T24587 306-310 PR:000001889 denotes CD14
T73947 312-316 PR:000001002 denotes CD19
T89548 318-322 PR:000001024 denotes CD56
T19748 324-328 PR:000001483 denotes CD16
T72909 391-398 GO:0010467 denotes express
T42475 439-447 GO:0065007 denotes regulate
T60194 482-487 NCBITaxon:10239 denotes viral
T44810 540-552 GO:0001906 denotes cell killing
T32910 595-604 CHEBI:36357;CHEBI:36357 denotes molecules
T22960 737-742 PR:000001895 denotes NKp30
T44851 744-749 PR:000001894 denotes NKp44
T80702 755-760 PR:000001893 denotes NKp46
T16057 797-802 PR:000001828 denotes NKG2D
T77902 855-861 PR:000001302 denotes DNAM-1
T79915 939-953 GO:0019814 denotes Immunoglobulin
T74826 1020-1024 PR:000001402 denotes CD94
T67433 1025-1030 PR:000002023 denotes NKG2A
T42783 1055-1062 CL:0000623;GO:0030101 denotes NK cell
T41884 1063-1073 GO:0030101 denotes activation
T11589 1108-1113 NCBITaxon:10239 denotes viral
T89698 1156-1169 GO:0016020 denotes transmembrane
T2180 1199-1204 NCBITaxon:10088 denotes mouse
T39420 1219-1224 SP_6;NCBITaxon:9606 denotes human
T87687 1225-1230 PR:000002024 denotes NKG2C
T94167 1270-1275 NCBITaxon:10239 denotes virus
T13325 1295-1299 PR:000001483 denotes CD16
T41985 1309-1317 GO:0042571 denotes antibody
T87350 1417-1428 NCBITaxon:10376 denotes herpesvirus
T34571 1474-1483 GO:0065007 denotes modulated
T81765 1628-1635 NCBITaxon:10239 denotes virally
T88477 1664-1671 CHEBI:59132;CHEBI:59132 denotes antigen
T19942 1699-1703 PR:000001379 denotes IL-2
T24466 1751-1755 GO:0008283 denotes cell
T12351 1916-1921 NCBITaxon:10239 denotes viral

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T78 0-8 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T79 3-8 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T80 23-34 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T81 91-96 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T82 203-211 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T83 206-211 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T84 248-253 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T85 254-264 Body_part denotes leukocytes http://purl.org/sig/ont/fma/fma62852
T86 338-346 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T87 341-346 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T88 504-509 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T89 537-544 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T90 540-544 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T91 672-679 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T92 675-679 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T93 939-953 Body_part denotes Immunoglobulin http://purl.org/sig/ont/fma/fma62871
T94 1055-1062 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T95 1058-1062 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T96 1247-1255 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T97 1250-1255 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T98 1285-1290 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T99 1309-1317 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T100 1328-1332 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T101 1454-1461 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T102 1457-1461 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T103 1487-1496 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T104 1544-1553 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T105 1554-1565 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T106 1566-1572 Body_part denotes (IL)-2 http://purl.org/sig/ont/fma/fma84051
T107 1567-1569 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T108 1645-1650 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 1664-1688 Body_part denotes antigen presenting cells http://purl.org/sig/ont/fma/fma273565
T110 1683-1688 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T111 1699-1703 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T112 1699-1701 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T113 1748-1755 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T114 1751-1755 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T115 1799-1807 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T116 1853-1861 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T117 1856-1861 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T15 248-253 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T82 482-497 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T83 488-497 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T84 616-625 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T85 1356-1360 Disease denotes ADCC http://purl.obolibrary.org/obo/MONDO_0008734
T86 1916-1932 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T128 0-8 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T129 91-96 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T130 106-107 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 188-194 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T132 203-211 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T133 248-253 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T134 248-253 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T135 301-304 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T136 301-304 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T137 312-316 http://purl.obolibrary.org/obo/CLO_0053432 denotes CD19
T138 338-346 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T139 454-462 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T140 504-509 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T141 537-544 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T142 661-671 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T143 672-679 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T144 826-836 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T145 977-979 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T146 1055-1062 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T147 1063-1073 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T148 1170-1180 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T149 1199-1204 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T150 1219-1224 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T151 1247-1255 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T152 1270-1275 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T153 1285-1290 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T154 1328-1332 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T155 1369-1372 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T156 1454-1461 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T157 1462-1470 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T158 1533-1543 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T159 1566-1572 http://purl.obolibrary.org/obo/PR_000001379 denotes (IL)-2
T160 1579-1581 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T161 1645-1650 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T162 1654-1663 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T163 1683-1688 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T164 1699-1703 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T165 1710-1712 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T166 1748-1755 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T167 1853-1861 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T16 595-604 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T17 891-898 Chemical denotes ligands http://purl.obolibrary.org/obo/CHEBI_52214
T18 1567-1569 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T20 1664-1671 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T21 1699-1701 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
299 744-749 Gene denotes NKp44 Gene:9436
300 755-760 Gene denotes NKp46 Gene:17086
301 797-802 Gene denotes NKG2D Gene:27007
302 855-861 Gene denotes DNAM-1 Gene:225825
303 1025-1030 Gene denotes NKG2A Gene:16641
304 1205-1210 Gene denotes Ly49H Gene:93968
305 1225-1230 Gene denotes NKG2C Gene:3822
306 1830-1835 Gene denotes IFN-γ Gene:3458
307 188-194 Species denotes humans Tax:9606
308 1199-1204 Species denotes mouse Tax:10090
309 1219-1224 Species denotes human Tax:9606
310 1417-1428 Species denotes herpesvirus Tax:39059
311 56-64 Disease denotes infected MESH:D007239
312 482-497 Disease denotes viral infection MESH:D001102
313 616-625 Disease denotes infection MESH:D007239
314 706-718 Disease denotes Cytotoxicity MESH:D064420
315 1276-1284 Disease denotes infected MESH:D007239
316 1342-1354 Disease denotes cytotoxicity MESH:D064420
317 1636-1644 Disease denotes infected MESH:D007239
318 1781-1793 Disease denotes cytotoxicity MESH:D064420
319 1916-1932 Disease denotes viral infections MESH:D001102

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T17 153-178 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T18 424-462 http://purl.obolibrary.org/obo/GO_0030545 denotes receptors that regulate their activity
T19 482-497 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T20 540-552 http://purl.obolibrary.org/obo/GO_0001906 denotes cell killing
T21 1055-1073 http://purl.obolibrary.org/obo/GO_0030101 denotes NK cell activation
T22 1058-1073 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T23 1356-1360 http://purl.obolibrary.org/obo/GO_0001788 denotes ADCC
T24 1664-1682 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen presenting
T25 1799-1818 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T26 1916-1932 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections

MyTest

Id Subject Object Predicate Lexical cue
32655581-21212348-34771617 180-182 21212348 denotes 62
32655581-25571788-34771618 333-335 25571788 denotes 63
32655581-21212348-34771619 464-466 21212348 denotes 62
32655581-15771571-34771620 468-470 15771571 denotes 64
32655581-23516982-34771621 472-474 23516982 denotes 65
32655581-19053900-34771622 643-645 19053900 denotes 66
32655581-27199990-34771623 647-649 27199990 denotes 67
32655581-25699048-34771624 763-765 25699048 denotes 68
32655581-29568297-34771625 814-816 29568297 denotes 69
32655581-26471195-34771626 863-865 26471195 denotes 70
32655581-7716543-34771627 977-979 7716543 denotes 71
32655581-7650366-34771627 977-979 7650366 denotes 71
32655581-7749980-34771627 977-979 7749980 denotes 71
32655581-9486650-34771628 1032-1034 9486650 denotes 74
32655581-9815261-34771629 1036-1038 9815261 denotes 75
32655581-24366517-34771630 1149-1151 24366517 denotes 76
32655581-29632329-34771631 1212-1214 29632329 denotes 77
32655581-19332875-34771632 1232-1234 19332875 denotes 78
32655581-31636622-34771633 1440-1442 31636622 denotes 79
32655581-20623510-34771634 1583-1585 20623510 denotes 80
32655581-12370359-34771635 1690-1692 12370359 denotes 81
32655581-28824650-34771636 1694-1696 28824650 denotes 82
32655581-20623510-34771637 1837-1839 20623510 denotes 80

TEST0

Id Subject Object Predicate Lexical cue
32655581-180-186-3171190 180-182 ["21212348"] denotes 62
32655581-148-154-3171191 333-335 ["25571788"] denotes 63
32655581-126-132-3171192 464-466 ["21212348"] denotes 62
32655581-130-136-3171193 468-470 ["15771571"] denotes 64
32655581-134-140-3171194 472-474 ["23516982"] denotes 65
32655581-166-172-3171195 643-645 ["19053900"] denotes 66
32655581-170-176-3171196 647-649 ["27199990"] denotes 67
32655581-229-235-3171197 763-765 ["25699048"] denotes 68
32655581-235-241-3171198 814-816 ["29568297"] denotes 69
32655581-228-234-3171199 863-865 ["26471195"] denotes 70
32655581-233-239-3171200 977-979 ["7716543", "7650366", "7749980"] denotes 71
32655581-235-241-3171201 1032-1034 ["9486650"] denotes 74
32655581-233-239-3171202 1036-1038 ["9815261"] denotes 75
32655581-235-241-3171203 1149-1151 ["24366517"] denotes 76
32655581-236-242-3171204 1212-1214 ["29632329"] denotes 77
32655581-233-239-3171205 1232-1234 ["19332875"] denotes 78
32655581-203-209-3171206 1440-1442 ["31636622"] denotes 79
32655581-138-144-3171207 1583-1585 ["20623510"] denotes 80
32655581-236-242-3171208 1690-1692 ["12370359"] denotes 81
32655581-237-243-3171209 1694-1696 ["28824650"] denotes 82
32655581-138-144-3171210 1837-1839 ["20623510"] denotes 80

2_test

Id Subject Object Predicate Lexical cue
32655581-21212348-34771617 180-182 21212348 denotes 62
32655581-25571788-34771618 333-335 25571788 denotes 63
32655581-21212348-34771619 464-466 21212348 denotes 62
32655581-15771571-34771620 468-470 15771571 denotes 64
32655581-23516982-34771621 472-474 23516982 denotes 65
32655581-19053900-34771622 643-645 19053900 denotes 66
32655581-27199990-34771623 647-649 27199990 denotes 67
32655581-25699048-34771624 763-765 25699048 denotes 68
32655581-29568297-34771625 814-816 29568297 denotes 69
32655581-26471195-34771626 863-865 26471195 denotes 70
32655581-7716543-34771627 977-979 7716543 denotes 71
32655581-7650366-34771627 977-979 7650366 denotes 71
32655581-7749980-34771627 977-979 7749980 denotes 71
32655581-9486650-34771628 1032-1034 9486650 denotes 74
32655581-9815261-34771629 1036-1038 9815261 denotes 75
32655581-24366517-34771630 1149-1151 24366517 denotes 76
32655581-29632329-34771631 1212-1214 29632329 denotes 77
32655581-19332875-34771632 1232-1234 19332875 denotes 78
32655581-31636622-34771633 1440-1442 31636622 denotes 79
32655581-20623510-34771634 1583-1585 20623510 denotes 80
32655581-12370359-34771635 1690-1692 12370359 denotes 81
32655581-28824650-34771636 1694-1696 28824650 denotes 82
32655581-20623510-34771637 1837-1839 20623510 denotes 80

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T62 0-184 Sentence denotes NK cells are cytotoxic lymphocytes that directly target infected, stressed, or transformed cells and play a critical role in bridging the innate and the adaptive immune responses (62).
T63 185-337 Sentence denotes In humans, mature NK cells comprise 10–15% of total peripheral blood leukocytes and are described phenotypically as CD3− CD14− CD19− CD56+ CD16+/− (63).
T64 338-476 Sentence denotes NK cells do not undergo clonal selection but instead express several germline-encoded receptors that regulate their activity (62, 64, 65).
T65 477-1236 Sentence denotes Upon viral infection, host cells become more susceptible to NK cell killing through: (i) upregulation of self-encoded molecules induced by infection/cellular stress (66, 67) that bind activating NK cell receptors such as Natural Cytotoxicity Receptors (NCRs) (NKp30, NKp44, and NKp46) (68), C-type lectin-like receptors NKG2D and NKp80 (69), and co-activating receptors such as DNAM-1 (70); (ii) downregulation of ligands for inhibitory receptors such as Killer Immunoglobulin-like Receptors (KIRs) (71–73) and the C-type lectin-like receptor CD94-NKG2A (74, 75) which suppress NK cell activation, and; (iii) direct recognition of viral moieties, via engagement of PAMPS (76) or transmembrane activating receptors such as mouse Ly49H (77) or human NKG2C (78).
T66 1237-1444 Sentence denotes Moreover, NK cells can eliminate virus-infected cells via CD16-mediated antibody-dependent cell-mediated cytotoxicity (ADCC), which has been shown to be particularly important for herpesvirus clearance (79).
T67 1445-1698 Sentence denotes Finally, NK cell activity is modulated by cytokines, including, but not limited to, the activating cytokines interleukin (IL)-2/12/15/18 (80) and type I IFN, which can be produced by virally infected cells or activated antigen presenting cells (81, 82).
T68 1699-1841 Sentence denotes IL-2/12/15/18, alone or in combination, promotes NK cell survival, proliferation, cytotoxicity, and cytokine production, including IFN-γ (80).
T69 1842-1933 Sentence denotes Therefore, NK cells are uniquely equipped to sense and quickly respond to viral infections.