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PMC:7324763 / 60919-62175 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T972 28-38 GO:0009986 denotes surface of
T973 48-56 GO:0065007 denotes regulate
T974 57-75 GO:0030101 denotes NK cell activation
T975 99-107 GO:0042571 denotes antibody
T976 180-185 PR:000002023 denotes NKG2A
T977 202-207 PR:000008614 denotes HLA-E
T978 224-229 PR:000002023 denotes NKG2A
T979 230-240 GO:0010467 denotes expression
T980 279-283 BV_4;UBERON:0001348 denotes BALF
T981 298-306 SP_7 denotes COVID-19
T982 332-337 PR:000002024 denotes NKG2C
T983 381-386 PR:000002023 denotes NKG2A
T984 475-480 PR:000002023 denotes NKG2A
T985 508-524 GO:0008283 denotes proliferation of
T986 525-530 PR:000002023 denotes NKG2A
T987 564-569 PR:000002023 denotes NKG2A
T988 626-633 UBERON:0000479 denotes tissues
T989 723-728 PR:000002023 denotes NKG2A
T990 842-847 PR:000002023 denotes NKG2A
T991 848-858 GO:0010467 denotes expression
T992 883-888 PR:000002023 denotes NKG2A
T993 903-908 PR:000002023 denotes NKG2A
T994 920-930 GO:0042571 denotes antibodies
T995 1000-1005 PR:000002023 denotes NKG2A
T996 1006-1016 GO:0010467 denotes expression
T997 1041-1049 SP_7 denotes COVID-19
T998 1112-1117 PR:000002023 denotes NKG2A
T999 1165-1170 PR:000002023 denotes NKG2A
T55610 28-38 GO:0009986 denotes surface of
T21667 48-56 GO:0065007 denotes regulate
T11086 57-75 GO:0030101 denotes NK cell activation
T91485 99-107 GO:0042571 denotes antibody
T4560 180-185 PR:000002023 denotes NKG2A
T22312 202-207 PR:000008614 denotes HLA-E
T54217 224-229 PR:000002023 denotes NKG2A
T44029 230-240 GO:0010467 denotes expression
T68837 279-283 BV_4;UBERON:0001348 denotes BALF
T71368 298-306 SP_7 denotes COVID-19
T47827 332-337 PR:000002024 denotes NKG2C
T12696 381-386 PR:000002023 denotes NKG2A
T13764 475-480 PR:000002023 denotes NKG2A
T6156 508-524 GO:0008283 denotes proliferation of
T48090 525-530 PR:000002023 denotes NKG2A
T67118 564-569 PR:000002023 denotes NKG2A
T4320 626-633 UBERON:0000479 denotes tissues
T6376 723-728 PR:000002023 denotes NKG2A
T97581 842-847 PR:000002023 denotes NKG2A
T35095 848-858 GO:0010467 denotes expression
T47409 883-888 PR:000002023 denotes NKG2A
T50460 903-908 PR:000002023 denotes NKG2A
T37146 920-930 GO:0042571 denotes antibodies
T62299 1000-1005 PR:000002023 denotes NKG2A
T6456 1006-1016 GO:0010467 denotes expression
T37564 1041-1049 SP_7 denotes COVID-19
T10574 1112-1117 PR:000002023 denotes NKG2A
T15085 1165-1170 PR:000002023 denotes NKG2A

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T761 39-47 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T762 42-47 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T763 57-64 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T764 60-64 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T765 99-107 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T766 202-205 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T767 284-292 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T768 287-292 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T769 482-490 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T770 485-490 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T771 532-537 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T772 579-584 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T773 626-633 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T774 647-655 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T775 650-655 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T776 1172-1180 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T777 1175-1180 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T440 298-306 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T441 682-693 Disease denotes hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T442 682-691 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T443 1041-1049 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T772 39-47 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T773 57-64 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T774 65-75 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T775 284-292 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T776 342-352 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T777 482-490 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T778 532-537 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T779 579-584 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T780 647-655 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T781 675-681 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T782 692-693 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T783 758-764 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T784 827-828 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T785 1062-1063 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T786 1172-1180 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T787 1202-1203 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T77102 782-791 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1743 180-185 Gene denotes NKG2A Gene:3821
1744 202-207 Gene denotes HLA-E Gene:3133
1745 224-229 Gene denotes NKG2A Gene:3821
1746 332-337 Gene denotes NKG2C Gene:3822
1747 381-386 Gene denotes NKG2A Gene:3821
1748 475-480 Gene denotes NKG2A Gene:3821
1749 525-530 Gene denotes NKG2A Gene:3821
1750 564-569 Gene denotes NKG2A Gene:3821
1751 723-728 Gene denotes NKG2A Gene:3821
1752 842-847 Gene denotes NKG2A Gene:3821
1753 883-888 Gene denotes NKG2A Gene:3821
1754 903-908 Gene denotes NKG2A Gene:3821
1755 1000-1005 Gene denotes NKG2A Gene:3821
1756 1112-1117 Gene denotes NKG2A Gene:3821
1757 1165-1170 Gene denotes NKG2A Gene:3821
1758 307-315 Species denotes patients Tax:9606
1759 661-669 Species denotes patients Tax:9606
1760 741-749 Species denotes patients Tax:9606
1761 1020-1028 Species denotes patients Tax:9606
1762 298-306 Disease denotes COVID-19 MESH:C000657245
1763 617-625 Disease denotes infected MESH:D007239
1764 682-701 Disease denotes hepatitis B disease MESH:D006509
1765 758-772 Disease denotes active disease OMIM:612348
1766 947-962 Disease denotes NK cytotoxicity MESH:D064420
1767 1041-1049 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T92 682-691 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T148 48-75 http://purl.obolibrary.org/obo/GO_0032814 denotes regulate NK cell activation
T149 57-75 http://purl.obolibrary.org/obo/GO_0030101 denotes NK cell activation
T150 60-75 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation

MyTest

Id Subject Object Predicate Lexical cue
32655581-9486650-34771785 209-211 9486650 denotes 74
32655581-30503213-34771786 213-216 30503213 denotes 198
32655581-30503208-34771787 218-221 30503208 denotes 199
32655581-32203188-34771788 270-273 32203188 denotes 127
32655581-23103614-34771789 964-967 23103614 denotes 200
32655581-32203188-34771790 1051-1054 32203188 denotes 127
32655581-32382127-34771791 1056-1059 32382127 denotes 201
32655581-24629893-34771792 1251-1254 24629893 denotes 202

TEST0

Id Subject Object Predicate Lexical cue
32655581-92-98-3171358 209-211 ["9486650"] denotes 74
32655581-96-103-3171359 213-216 ["30503213"] denotes 198
32655581-101-108-3171360 218-221 ["30503208"] denotes 199
32655581-46-53-3171361 270-273 ["32203188"] denotes 127
32655581-104-111-3171362 964-967 ["23103614"] denotes 200
32655581-81-88-3171363 1051-1054 ["32203188"] denotes 127
32655581-86-93-3171364 1056-1059 ["32382127"] denotes 201
32655581-234-241-3171365 1251-1254 ["24629893"] denotes 202

2_test

Id Subject Object Predicate Lexical cue
32655581-9486650-34771785 209-211 9486650 denotes 74
32655581-30503213-34771786 213-216 30503213 denotes 198
32655581-30503208-34771787 218-221 30503208 denotes 199
32655581-32203188-34771788 270-273 32203188 denotes 127
32655581-23103614-34771789 964-967 23103614 denotes 200
32655581-32203188-34771790 1051-1054 32203188 denotes 127
32655581-32382127-34771791 1056-1059 32382127 denotes 201
32655581-24629893-34771792 1251-1254 24629893 denotes 202

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T371 0-116 Sentence denotes Inhibitory receptors on the surface of NK cells regulate NK cell activation and can be targeted by antibody therapy.
T372 117-223 Sentence denotes One of the most promising is certainly the inhibitory receptor NKG2A, which binds to HLA-E (74, 198, 199).
T373 224-418 Sentence denotes NKG2A expression is increased in circulating (127) and BALF NK cells from COVID-19 patients, in contrast to NKG2C, an activating receptor closely related to NKG2A, which remains unchanged (129).
T374 419-634 Sentence denotes However, it is unclear whether the observed increase in NKG2A+ NK cells is due selective proliferation of NKG2A+ cells or if it is the result of NKG2A negative cells migrating out of circulation to infected tissues.
T375 635-859 Sentence denotes Circulating NK cells from patients with active hepatitis B disease had higher levels of NKG2A compared to patients without active disease, however antiviral administration was associated with a reduction in NKG2A expression.
T376 860-969 Sentence denotes Additionally, blocking NKG2A in vitro with NKG2A monoclonal antibodies led to improved NK cytotoxicity (200).
T377 970-1256 Sentence denotes Given the association between NKG2A expression in patients with severe COVID-19 (127, 201), a promising avenue of investigation would be anti-NKG2A therapy, even in light of results showing that NKG2A+ NK cells are tuned to present a higher level of responsiveness to stimulation (202).