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PMC:7324763 / 18031-27153 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T377 31-42 NCBITaxon:11118 denotes Coronavirus
T378 132-140 SP_7 denotes COVID-19
T379 176-187 NCBITaxon:11118 denotes coronavirus
T380 237-241 NCBITaxon:10088 denotes mice
T381 269-277 SP_10 denotes SARS-CoV
T382 317-328 CL:0000542 denotes lymphocytes
T383 383-391 SP_10 denotes SARS-CoV
T384 397-403 NCBITaxon:39107 denotes murine
T385 469-477 GO:0051716 denotes cellular
T386 478-484 UBERON:0002405;GO:0006955 denotes immune
T387 485-493 GO:0006955 denotes response
T388 497-505 SP_10 denotes SARS-CoV
T389 534-538 NCBITaxon:10088 denotes mice
T390 540-546 CL:0000084 denotes T cell
T391 573-580 GO:0065007 denotes control
T392 584-592 SP_10 denotes SARS-CoV
T393 595-606 GO:0006260 denotes replication
T394 647-660 UBERON:0002405 denotes immune system
T395 679-684 NCBITaxon:10239 denotes viral
T396 723-726 PR:000001004 denotes CD4
T397 758-762 UBERON:0002048 denotes lung
T398 791-796 NCBITaxon:10239 denotes viral
T399 843-848 NCBITaxon:10239;GO:0006260 denotes viral
T400 849-860 GO:0006260 denotes replication
T401 915-918 PR:000001004 denotes CD4
T402 920-927 CL:0000084 denotes T cells
T403 931-942 NCBITaxon:11118 denotes coronavirus
T404 1026-1032 NCBITaxon:39107 denotes murine
T405 1057-1061 NCBITaxon:10088 denotes mice
T406 1063-1071 SP_10 denotes SARS-CoV
T407 1155-1160 UBERON:0000170 denotes lungs
T408 1180-1188 SP_10 denotes SARS-CoV
T409 1316-1333 CL:0009002 denotes inflammatory cell
T410 1356-1361 UBERON:0000170 denotes lungs
T411 1375-1380 NCBITaxon:10088 denotes mouse
T412 1415-1419 SP_10 denotes SARS
T413 1569-1575 NCBITaxon:33208 denotes animal
T414 1657-1665 SP_7 denotes COVID-19
T415 1704-1714 SP_7 denotes SARS-CoV-2
T416 1715-1721 NCBITaxon:39107 denotes murine
T417 1737-1742 NCBITaxon:10508 denotes adeno
T418 1754-1759 NCBITaxon:10239 denotes virus
T419 1776-1786 GO:0010467 denotes expression
T420 1790-1795 SP_6;NCBITaxon:9606 denotes human
T421 1799-1803 G_3;PG_10;PR:000003622 denotes ACE2
T422 1855-1863 SP_7 denotes COVID-19
T423 1924-1930 NCBITaxon:39107 denotes murine
T424 1934-1938 G_3;PG_10;PR:000003622 denotes ACE2
T425 1950-1960 SP_7 denotes SARS-CoV-2
T426 2028-2038 SP_7 denotes SARS-CoV-2
T427 2039-2050 GO:0006260 denotes replication
T428 2125-2130 PR:Q8R0I0 denotes mACE2
T429 2179-2184 NCBITaxon:10239 denotes virus
T430 2186-2196 SP_7 denotes SARS-CoV-2
T431 2218-2227 PG_1 denotes S protein
T432 2228-2233 PR:Q8R0I0 denotes mACE2
T433 2251-2261 GO:0006260 denotes replicated
T434 2281-2288 UBERON:0001005 denotes airways
T435 2307-2311 NCBITaxon:10088 denotes mice
T436 2351-2355 NCBITaxon:10088 denotes mice
T437 2595-2600 PG_10;PR:Q9BYF1 denotes hACE2
T438 2662-2666 NCBITaxon:10088 denotes mice
T439 2783-2788 UBERON:0000178 denotes blood
T440 2794-2802 SP_7 denotes COVID-19
T441 2866-2871 UBERON:0000178 denotes blood
T442 2929-2937 SP_7 denotes COVID-19
T443 3002-3013 CL:0000080 denotes circulating
T444 3084-3095 CL:0000080 denotes circulating
T445 3143-3153 GO:0010467 denotes expression
T446 3181-3186 PR:000002023 denotes NKG2A
T447 3244-3249 PR:000000017 denotes IFN-γ
T448 3274-3277 PR:000000134 denotes TNF
T449 3282-3286 PR:000001379 denotes IL-2
T450 3292-3302 PR:000003499 denotes granzyme B
T451 3428-3436 SP_7 denotes COVID-19
T452 3478-3483 PR:000002023 denotes NKG2A
T453 3484-3494 GO:0010467 denotes expression
T454 3570-3585 UBERON:0004821;BV_4 denotes bronchoalveolar
T455 3586-3592 BV_4;UBERON:0001796 denotes lavage
T456 3593-3598 BV_4;UBERON:0006314 denotes fluid
T457 3618-3626 SP_7 denotes COVID-19
T458 3651-3659 SP_7 denotes COVID-19
T459 3692-3699 CL:0000623 denotes NK cell
T460 3721-3726 UBERON:0000170 denotes lungs
T461 3792-3800 CL:0000623 denotes NK cells
T462 3821-3826 PR:000002023 denotes KLRC1
T463 3828-3833 PR:000002023 denotes NKG2A
T464 3839-3844 PR:000001402 denotes KLRD1
T465 3846-3850 PR:000001402 denotes CD94
T466 3864-3873 GO:0010467 denotes expressed
T467 3918-3925 CL:0000763 denotes myeloid
T468 3977-3982 UBERON:0000178 denotes blood
T469 3987-4002 UBERON:0002186;BV_4 denotes bronchoalveolar
T470 4003-4009 BV_4 denotes lavage
T471 4010-4015 BV_4;UBERON:0006314 denotes fluid
T472 4017-4021 BV_4 denotes BALF
T473 4067-4075 SP_7 denotes COVID-19
T474 4142-4152 SP_7 denotes SARS-CoV-2
T475 4188-4198 CL:0000080 denotes peripheral
T476 4199-4204 CL:0000080;UBERON:0000178 denotes blood
T477 4205-4216 CL:0000542 denotes lymphocytes
T478 4231-4236 CL:0000623 denotes cells
T479 4439-4444 PR:000002023 denotes NKG2A
T480 4446-4450 PR:000001919 denotes PD-1
T481 4456-4460 PR:000001854 denotes CD39
T482 4531-4539 SP_7 denotes COVID-19
T483 4633-4641 SP_7 denotes COVID-19
T484 4659-4666 PR:000001024 denotes CD56dim
T485 4720-4728 SP_7 denotes COVID-19
T486 4766-4776 GO:0010467 denotes expression
T487 4803-4807 PR:000001881 denotes LAG3
T488 4812-4818 PR:000008454 denotes HAVCR2
T489 4890-4900 SP_7 denotes SARS-CoV-2
T490 5112-5122 SP_7 denotes SARS-CoV-2
T491 5267-5269 CL:0000540 denotes NK
T492 5313-5318 UBERON:0000178 denotes blood
T493 5328-5332 SP_10 denotes SARS
T494 5458-5462 SP_10 denotes SARS
T495 5533-5542 NCBITaxon:2 denotes bacterium
T496 5543-5564 NCBITaxon:2104 denotes Mycoplasma pneumoniae
T497 5653-5661 SP_10 denotes SARS CoV
T498 5671-5674 GO:0071735 denotes IgG
T499 5678-5692 GO:0071754 denotes IgM antibodies
T500 5911-5919 SP_10 denotes SARS-CoV
T501 6135-6139 SP_10 denotes SARS
T502 6224-6228 SP_10 denotes SARS
T503 6249-6253 SP_9 denotes MERS
T504 6373-6384 CL:0000080 denotes circulating
T505 6487-6492 UBERON:0000178 denotes blood
T506 6545-6556 CL:0000080 denotes circulating
T507 6594-6599 UBERON:0000178 denotes blood
T508 6627-6634 UBERON:0000479 denotes tissues
T509 6669-6671 GO:0001764 denotes NK
T510 6672-6686 GO:0016477 denotes cell migration
T511 6699-6706 UBERON:0000479 denotes tissues
T512 6710-6718 SP_7 denotes COVID-19
T513 6765-6770 NCBITaxon:10088 denotes mouse
T514 6829-6834 UBERON:0000170 denotes lungs
T515 6851-6858 NCBITaxon:33208 denotes animals
T516 6910-6915 PR:000000046 denotes TGF-β
T517 6993-7001 SP_7 denotes COVID-19
T518 7083-7088 PR:000000046 denotes TGF-β
T519 7099-7103 SP_10 denotes SARS
T520 7224-7229 PR:000000046 denotes TGF-β
T521 7305-7310 PR:000000046 denotes TGF-β
T522 7442-7450 SP_7 denotes COVID-19
T523 7564-7574 SP_7 denotes SARS-CoV-2
T524 7598-7606 CL:0000623 denotes NK cells
T525 7706-7713 CL:0000623 denotes NK cell
T526 7782-7790 SP_7 denotes COVID-19
T527 7975-7993 GO:0030101 denotes NK cell activation
T528 8104-8115 NCBITaxon:1 denotes individuals
T529 8329-8339 SP_7 denotes SARS-CoV-2
T530 8363-8368 NCBITaxon:10239 denotes viral
T531 8495-8500 NCBITaxon:10239;GO:0006260 denotes viral
T532 8581-8583 CL:0000540 denotes NK
T533 8650-8655 UBERON:0000178 denotes blood
T534 8713-8716 CHEBI:60004;CHEBI:60004 denotes mix
T535 8746-8751 PR:000000017 denotes IFN-γ
T536 8878-8883 NCBITaxon:10239 denotes viral
T537 9016-9022 GO:0045087 denotes innate
T538 9023-9029 GO:0045087;UBERON:0002405 denotes immune
T539 9030-9038 GO:0045087 denotes response
T540 9081-9088 CL:0000623 denotes NK cell
T541 9106-9111 NCBITaxon:10239 denotes viral
T45287 31-42 NCBITaxon:11118 denotes Coronavirus
T98467 132-140 SP_7 denotes COVID-19
T70031 176-187 NCBITaxon:11118 denotes coronavirus
T76483 237-241 NCBITaxon:10088 denotes mice
T94576 269-277 SP_10 denotes SARS-CoV
T79015 317-328 CL:0000542 denotes lymphocytes
T30662 383-391 SP_10 denotes SARS-CoV
T39613 397-403 NCBITaxon:39107 denotes murine
T73677 469-477 GO:0051716 denotes cellular
T52881 478-484 UBERON:0002405;GO:0006955 denotes immune
T20584 485-493 GO:0006955 denotes response
T18542 497-505 SP_10 denotes SARS-CoV
T1957 534-538 NCBITaxon:10088 denotes mice
T69844 540-546 CL:0000084 denotes T cell
T21640 573-580 GO:0065007 denotes control
T16986 584-592 SP_10 denotes SARS-CoV
T25404 595-606 GO:0006260 denotes replication
T23602 647-660 UBERON:0002405 denotes immune system
T22713 679-684 NCBITaxon:10239 denotes viral
T6710 723-726 PR:000001004 denotes CD4
T55621 758-762 UBERON:0002048 denotes lung
T35629 791-796 NCBITaxon:10239 denotes viral
T58361 843-848 NCBITaxon:10239;GO:0006260 denotes viral
T4980 849-860 GO:0006260 denotes replication
T8796 915-918 PR:000001004 denotes CD4
T16605 920-927 CL:0000084 denotes T cells
T81822 931-942 NCBITaxon:11118 denotes coronavirus
T83773 1026-1032 NCBITaxon:39107 denotes murine
T77578 1057-1061 NCBITaxon:10088 denotes mice
T57972 1063-1071 SP_10 denotes SARS-CoV
T47152 1155-1160 UBERON:0000170 denotes lungs
T20046 1180-1188 SP_10 denotes SARS-CoV
T31676 1316-1333 CL:0009002 denotes inflammatory cell
T85438 1356-1361 UBERON:0000170 denotes lungs
T47384 1375-1380 NCBITaxon:10088 denotes mouse
T38092 1415-1419 SP_10 denotes SARS
T98916 1569-1575 NCBITaxon:33208 denotes animal
T97072 1657-1665 SP_7 denotes COVID-19
T25892 1704-1714 SP_7 denotes SARS-CoV-2
T30086 1715-1721 NCBITaxon:39107 denotes murine
T18781 1737-1742 NCBITaxon:10508 denotes adeno
T55342 1754-1759 NCBITaxon:10239 denotes virus
T84584 1776-1786 GO:0010467 denotes expression
T63378 1790-1795 SP_6;NCBITaxon:9606 denotes human
T91924 1799-1803 G_3;PG_10;PR:000003622 denotes ACE2
T13801 1855-1863 SP_7 denotes COVID-19
T74721 1924-1930 NCBITaxon:39107 denotes murine
T79834 1934-1938 G_3;PG_10;PR:000003622 denotes ACE2
T24866 1950-1960 SP_7 denotes SARS-CoV-2
T67334 2028-2038 SP_7 denotes SARS-CoV-2
T80984 2039-2050 GO:0006260 denotes replication
T30397 2125-2130 PR:Q8R0I0 denotes mACE2
T99161 2179-2184 NCBITaxon:10239 denotes virus
T50168 2186-2196 SP_7 denotes SARS-CoV-2
T52446 2218-2227 PG_1 denotes S protein
T50328 2228-2233 PR:Q8R0I0 denotes mACE2
T56113 2251-2261 GO:0006260 denotes replicated
T67080 2281-2288 UBERON:0001005 denotes airways
T5105 2307-2311 NCBITaxon:10088 denotes mice
T63298 2351-2355 NCBITaxon:10088 denotes mice
T8162 2595-2600 PG_10;PR:Q9BYF1 denotes hACE2
T93442 2662-2666 NCBITaxon:10088 denotes mice
T42454 2783-2788 UBERON:0000178 denotes blood
T89458 2794-2802 SP_7 denotes COVID-19
T91674 2866-2871 UBERON:0000178 denotes blood
T17225 2929-2937 SP_7 denotes COVID-19
T20103 3002-3013 CL:0000080 denotes circulating
T91031 3084-3095 CL:0000080 denotes circulating
T76320 3143-3153 GO:0010467 denotes expression
T9653 3181-3186 PR:000002023 denotes NKG2A
T4305 3244-3249 PR:000000017 denotes IFN-γ
T63694 3274-3277 PR:000000134 denotes TNF
T83273 3282-3286 PR:000001379 denotes IL-2
T27759 3292-3302 PR:000003499 denotes granzyme B
T94929 3428-3436 SP_7 denotes COVID-19
T15712 3478-3483 PR:000002023 denotes NKG2A
T45327 3484-3494 GO:0010467 denotes expression
T41546 3570-3585 UBERON:0004821;BV_4 denotes bronchoalveolar
T17261 3586-3592 BV_4;UBERON:0001796 denotes lavage
T89631 3593-3598 BV_4;UBERON:0006314 denotes fluid
T19856 3618-3626 SP_7 denotes COVID-19
T49469 3651-3659 SP_7 denotes COVID-19
T39192 3692-3699 CL:0000623 denotes NK cell
T34320 3721-3726 UBERON:0000170 denotes lungs
T27415 3792-3800 CL:0000623 denotes NK cells
T9598 3821-3826 PR:000002023 denotes KLRC1
T56427 3828-3833 PR:000002023 denotes NKG2A
T75923 3839-3844 PR:000001402 denotes KLRD1
T79032 3846-3850 PR:000001402 denotes CD94
T22434 3864-3873 GO:0010467 denotes expressed
T55955 3918-3925 CL:0000763 denotes myeloid
T74842 3977-3982 UBERON:0000178 denotes blood
T77526 3987-4002 UBERON:0002186;BV_4 denotes bronchoalveolar
T64097 4003-4009 BV_4 denotes lavage
T18922 4010-4015 BV_4;UBERON:0006314 denotes fluid
T34649 4017-4021 BV_4 denotes BALF
T9346 4067-4075 SP_7 denotes COVID-19
T81698 4142-4152 SP_7 denotes SARS-CoV-2
T10715 4188-4198 CL:0000080 denotes peripheral
T14632 4199-4204 CL:0000080;UBERON:0000178 denotes blood
T91797 4205-4216 CL:0000542 denotes lymphocytes
T91378 4231-4236 CL:0000623 denotes cells
T74592 4439-4444 PR:000002023 denotes NKG2A
T40676 4446-4450 PR:000001919 denotes PD-1
T70051 4456-4460 PR:000001854 denotes CD39
T75459 4531-4539 SP_7 denotes COVID-19
T30941 4633-4641 SP_7 denotes COVID-19
T66470 4659-4666 PR:000001024 denotes CD56dim
T40968 4720-4728 SP_7 denotes COVID-19
T13102 4766-4776 GO:0010467 denotes expression
T42827 4803-4807 PR:000001881 denotes LAG3
T19476 4812-4818 PR:000008454 denotes HAVCR2
T62958 4890-4900 SP_7 denotes SARS-CoV-2
T20800 5112-5122 SP_7 denotes SARS-CoV-2
T21411 5267-5269 CL:0000540 denotes NK
T7113 5313-5318 UBERON:0000178 denotes blood
T88576 5328-5332 SP_10 denotes SARS
T5730 5458-5462 SP_10 denotes SARS
T9639 5533-5542 NCBITaxon:2 denotes bacterium
T96207 5543-5564 NCBITaxon:2104 denotes Mycoplasma pneumoniae
T53775 5653-5661 SP_10 denotes SARS CoV
T94196 5671-5674 GO:0071735 denotes IgG
T20181 5678-5692 GO:0071754 denotes IgM antibodies
T88542 5911-5919 SP_10 denotes SARS-CoV
T86691 6135-6139 SP_10 denotes SARS
T49193 6224-6228 SP_10 denotes SARS
T92665 6249-6253 SP_9 denotes MERS
T5395 6373-6384 CL:0000080 denotes circulating
T82047 6487-6492 UBERON:0000178 denotes blood
T67265 6545-6556 CL:0000080 denotes circulating
T44979 6594-6599 UBERON:0000178 denotes blood
T36639 6627-6634 UBERON:0000479 denotes tissues
T49830 6669-6671 GO:0001764 denotes NK
T21794 6672-6686 GO:0016477 denotes cell migration
T46028 6699-6706 UBERON:0000479 denotes tissues
T32473 6710-6718 SP_7 denotes COVID-19
T43165 6765-6770 NCBITaxon:10088 denotes mouse
T66553 6829-6834 UBERON:0000170 denotes lungs
T88481 6851-6858 NCBITaxon:33208 denotes animals
T47753 6910-6915 PR:000000046 denotes TGF-β
T10864 6993-7001 SP_7 denotes COVID-19
T78427 7083-7088 PR:000000046 denotes TGF-β
T57014 7099-7103 SP_10 denotes SARS
T22695 7224-7229 PR:000000046 denotes TGF-β
T40869 7305-7310 PR:000000046 denotes TGF-β
T21135 7442-7450 SP_7 denotes COVID-19
T16069 7564-7574 SP_7 denotes SARS-CoV-2
T66007 7598-7606 CL:0000623 denotes NK cells
T85394 7706-7713 CL:0000623 denotes NK cell
T51078 7782-7790 SP_7 denotes COVID-19
T25814 7975-7993 GO:0030101 denotes NK cell activation
T94150 8104-8115 NCBITaxon:1 denotes individuals
T96496 8329-8339 SP_7 denotes SARS-CoV-2
T45332 8363-8368 NCBITaxon:10239 denotes viral
T22499 8495-8500 NCBITaxon:10239;GO:0006260 denotes viral
T23101 8581-8583 CL:0000540 denotes NK
T66641 8650-8655 UBERON:0000178 denotes blood
T64998 8713-8716 CHEBI:60004;CHEBI:60004 denotes mix
T85326 8746-8751 PR:000000017 denotes IFN-γ
T14234 8878-8883 NCBITaxon:10239 denotes viral
T7574 9016-9022 GO:0045087 denotes innate
T53507 9023-9029 GO:0045087;UBERON:0002405 denotes immune
T54146 9030-9038 GO:0045087 denotes response
T94634 9081-9088 CL:0000623 denotes NK cell
T50242 9106-9111 NCBITaxon:10239 denotes viral

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T207 0-7 Body_part denotes NK Cell http://purl.org/sig/ont/fma/fma63147
T208 3-7 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T209 111-119 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T210 114-119 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T211 317-328 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T212 340-348 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T213 343-348 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T214 542-546 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T215 647-660 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T216 666-674 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T217 669-674 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T218 758-762 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T219 922-927 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T220 1119-1128 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T221 1155-1160 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T222 1329-1333 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T223 1356-1361 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T224 2220-2227 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T225 2700-2707 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T226 2703-2707 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T227 2783-2788 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T228 2833-2840 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T229 2836-2840 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T230 2866-2871 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T231 3014-3022 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T232 3017-3022 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T233 3096-3104 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T234 3099-3104 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T235 3282-3286 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T236 3282-3284 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T237 3459-3467 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T238 3462-3467 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T239 3531-3535 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T240 3550-3555 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T241 3692-3699 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T242 3695-3699 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T243 3721-3726 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T244 3792-3800 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T245 3795-3800 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T246 3877-3885 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T247 3880-3885 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T248 3977-3982 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T249 4199-4204 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T250 4205-4216 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T251 4228-4236 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T252 4231-4236 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T253 4366-4374 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T254 4369-4374 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T255 4413-4421 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T256 4416-4421 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T257 4506-4510 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T258 4511-4514 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T259 4743-4751 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T260 4746-4751 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T261 4826-4833 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T262 4829-4833 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T263 4977-4984 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T264 4980-4984 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T265 5143-5150 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T266 5146-5150 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T267 5161-5168 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T268 5164-5168 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T269 5267-5274 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T270 5270-5274 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T271 5313-5318 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T272 5389-5396 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T273 5392-5396 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T274 5572-5579 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T275 5575-5579 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T276 5671-5674 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T277 5678-5681 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T278 5717-5725 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T279 5720-5725 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T280 5933-5940 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T281 5936-5940 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T282 6116-6123 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T283 6119-6123 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T284 6385-6393 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T285 6388-6393 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T286 6487-6492 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T287 6493-6501 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T288 6496-6501 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T289 6557-6565 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T290 6560-6565 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T291 6594-6599 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T292 6600-6608 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T293 6603-6608 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T294 6627-6634 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T295 6669-6676 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T296 6672-6676 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T297 6699-6706 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T298 6786-6794 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T299 6789-6794 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T300 6829-6834 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T301 6954-6961 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T302 6957-6961 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T303 7245-7252 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T304 7248-7252 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T305 7340-7349 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T306 7391-7398 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T307 7394-7398 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T308 7598-7606 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T309 7601-7606 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T310 7706-7713 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T311 7709-7713 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T312 7975-7982 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T313 7978-7982 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T314 8300-8308 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T315 8303-8308 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T316 8408-8415 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T317 8411-8415 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T318 8416-8427 Body_part denotes compartment http://purl.org/sig/ont/fma/fma76577
T319 8469-8476 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T320 8472-8476 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T321 8581-8588 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T322 8584-8588 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T323 8650-8655 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T324 8676-8683 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T325 8679-8683 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T326 8704-8712 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T327 9081-9088 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T328 9084-9088 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T19 647-660 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T20 758-762 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T21 2783-2788 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T22 2866-2871 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T23 3977-3982 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T24 4199-4204 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T25 5313-5318 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T26 6487-6492 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T27 6594-6599 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T28 8650-8655 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T132 132-140 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 188-198 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T134 269-277 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T135 269-273 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T136 383-391 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T137 383-387 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T138 497-505 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T139 497-501 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T140 584-592 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T141 584-588 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T142 943-952 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T143 1063-1071 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T144 1063-1067 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T145 1103-1114 Disease denotes pneumonitis http://purl.obolibrary.org/obo/MONDO_0043905
T146 1180-1188 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T147 1180-1184 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T148 1415-1419 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T149 1657-1665 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T150 1704-1712 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T151 1704-1708 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T152 1855-1863 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T153 1950-1958 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T154 1950-1954 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T155 1961-1970 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T156 2028-2036 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T157 2028-2032 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T158 2186-2194 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T159 2186-2190 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T160 2794-2802 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T161 2929-2937 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T162 3251-3256 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T163 3428-3436 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T164 3618-3626 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T165 3651-3659 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T166 4067-4075 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T167 4089-4098 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T168 4130-4134 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T169 4142-4150 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T170 4142-4146 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T171 4272-4281 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T172 4286-4290 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T173 4404-4408 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T174 4531-4539 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T175 4633-4641 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T176 4720-4728 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T177 4890-4898 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T178 4890-4894 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T179 5101-5110 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T180 5112-5120 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T181 5112-5116 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T182 5328-5332 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T183 5458-5462 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T184 5543-5564 Disease denotes Mycoplasma pneumoniae http://purl.obolibrary.org/obo/MONDO_0005867
T185 5653-5657 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T186 5911-5919 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T187 5911-5915 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T188 5922-5931 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T189 6014-6025 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T190 6135-6139 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T191 6224-6228 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T192 6254-6263 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T193 6303-6314 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T194 6710-6718 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T195 6993-7001 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T196 7099-7103 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T197 7442-7450 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T198 7486-7496 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T199 7519-7528 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T200 7532-7542 Disease denotes bacteremia http://purl.obolibrary.org/obo/MONDO_0005229
T201 7564-7572 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T202 7564-7568 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T203 7575-7584 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T204 7681-7691 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T205 7782-7790 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T206 7855-7865 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T207 8024-8033 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T208 8329-8337 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T209 8329-8333 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T210 8363-8378 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T211 8369-8378 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T212 8950-8956 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T213 9046-9055 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T255 0-7 http://purl.obolibrary.org/obo/CL_0000623 denotes NK Cell
T256 73-74 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T257 111-119 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T258 245-246 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T259 340-348 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T260 430-431 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T261 540-546 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T262 625-626 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T263 647-660 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T264 666-674 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T265 723-726 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T266 758-762 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T267 758-762 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T268 814-817 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T269 915-918 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T270 920-927 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T271 1044-1047 http://purl.obolibrary.org/obo/CLO_0001382 denotes 4–8
T272 1155-1160 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T273 1167-1170 http://purl.obolibrary.org/obo/CLO_0001053 denotes 121
T274 1178-1179 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T275 1221-1222 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T276 1329-1333 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T277 1356-1361 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T278 1375-1380 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T279 1513-1516 http://purl.obolibrary.org/obo/CLO_0001053 denotes 121
T280 1560-1561 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T281 1569-1575 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T282 1702-1703 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T283 1754-1759 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T284 1790-1795 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T285 2061-2062 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T286 2165-2166 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T287 2179-2184 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T288 2206-2207 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T289 2281-2288 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T290 2473-2474 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T291 2536-2539 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T292 2674-2675 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T293 2700-2707 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T294 2731-2734 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T295 2783-2788 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T296 2783-2788 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T297 2833-2840 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T298 2866-2871 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T299 2866-2871 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T300 3014-3022 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T301 3096-3104 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T302 3282-3286 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T303 3301-3302 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T304 3387-3393 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T305 3459-3467 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T306 3531-3535 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T307 3550-3555 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T308 3692-3699 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T309 3721-3726 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T310 3792-3800 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T311 3877-3885 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T312 3977-3982 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T313 3977-3982 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T314 4086-4088 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T315 4199-4204 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T316 4199-4204 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T317 4228-4236 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T318 4366-4374 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T319 4413-4421 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T320 4506-4510 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T321 4743-4751 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T322 4826-4833 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T323 4856-4857 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T324 4977-4984 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T325 5076-5077 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T326 5143-5150 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T327 5161-5168 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T328 5267-5274 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T329 5313-5318 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T330 5313-5318 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T331 5383-5386 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T332 5389-5396 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T333 5572-5579 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T334 5717-5725 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T335 5727-5730 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T336 5933-5940 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T337 6069-6072 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T338 6101-6102 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T339 6116-6123 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T340 6385-6393 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T341 6465-6472 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T342 6487-6492 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T343 6487-6492 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T344 6493-6501 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T345 6557-6565 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T346 6594-6599 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T347 6594-6599 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T348 6600-6608 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T349 6669-6676 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T350 6765-6770 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T351 6786-6794 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T352 6829-6834 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T353 6851-6858 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T354 6954-6961 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T355 7245-7252 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T356 7391-7398 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T357 7409-7417 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T358 7546-7547 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T359 7598-7606 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T360 7647-7648 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T361 7699-7700 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T362 7706-7713 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T363 7875-7876 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T364 7975-7982 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T365 7983-7993 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T366 8289-8290 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T367 8300-8308 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T368 8379-8382 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T369 8383-8384 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T370 8408-8415 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T371 8469-8476 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T372 8477-8485 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T373 8544-8545 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T374 8565-8569 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T375 8581-8588 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T376 8644-8655 http://purl.obolibrary.org/obo/UBERON_0000178 denotes whole blood
T377 8644-8655 http://www.ebi.ac.uk/efo/EFO_0000296 denotes whole blood
T378 8676-8683 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T379 8693-8703 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T380 8721-8729 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T381 8930-8933 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T382 9081-9088 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T41 1200-1202 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T44 2197-2199 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T47 2220-2227 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T48 3282-3284 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T50 4446-4448 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T51 7399-7408 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
513 25-53 Disease denotes Acute Coronavirus Infections MESH:D018352
557 723-726 Gene denotes CD4 Gene:12504
558 814-817 Gene denotes CD8 Gene:925
559 915-918 Gene denotes CD4 Gene:12504
560 1799-1803 Gene denotes ACE2 Gene:59272
561 1934-1938 Gene denotes ACE2 Gene:70008
562 2462-2469 Gene denotes IFN-λ-1 Gene:282618
563 2595-2600 Gene denotes hACE2 Gene:59272
564 2125-2130 Gene denotes mACE2 Gene:70008
565 2228-2233 Gene denotes mACE2 Gene:70008
566 237-241 Species denotes mice Tax:10090
567 269-277 Species denotes SARS-CoV Tax:694009
568 383-391 Species denotes SARS-CoV Tax:694009
569 397-403 Species denotes murine Tax:10090
570 497-505 Species denotes SARS-CoV Tax:694009
571 534-538 Species denotes mice Tax:10090
572 584-592 Species denotes SARS-CoV Tax:694009
573 1022-1025 Species denotes CoV Tax:11118
574 1026-1032 Species denotes murine Tax:10090
575 1057-1061 Species denotes mice Tax:10090
576 1063-1071 Species denotes SARS-CoV Tax:694009
577 1180-1188 Species denotes SARS-CoV Tax:694009
578 1375-1380 Species denotes mouse Tax:10090
579 1704-1714 Species denotes SARS-CoV-2 Tax:2697049
580 1715-1721 Species denotes murine Tax:10090
581 1737-1759 Species denotes adeno associated virus Tax:272636
582 1790-1795 Species denotes human Tax:9606
583 1864-1872 Species denotes patients Tax:9606
584 1924-1930 Species denotes murine Tax:10090
585 2028-2038 Species denotes SARS-CoV-2 Tax:2697049
586 2186-2196 Species denotes SARS-CoV-2 Tax:2697049
587 2307-2311 Species denotes mice Tax:10090
588 2351-2355 Species denotes mice Tax:10090
589 2662-2666 Species denotes mice Tax:10090
590 2584-2594 Species denotes transgenic Tax:10090
591 132-140 Disease denotes COVID-19 MESH:C000657245
592 176-198 Disease denotes coronavirus infections MESH:D018352
593 931-952 Disease denotes coronavirus infection MESH:D018352
594 1103-1114 Disease denotes pneumonitis MESH:D011014
595 1257-1264 Disease denotes viremia MESH:D014766
596 1269-1278 Disease denotes mortality MESH:D003643
597 1657-1665 Disease denotes COVID-19 MESH:C000657245
598 1855-1863 Disease denotes COVID-19 MESH:C000657245
599 1950-1970 Disease denotes SARS-CoV-2 infection MESH:C000657245
648 3181-3186 Gene denotes NKG2A Gene:3821
649 3244-3249 Gene denotes IFN-γ Gene:3458
650 3251-3280 Gene denotes tumor necrosis factor (TNF)-α Gene:7124
651 3282-3286 Gene denotes IL-2 Gene:3558
652 3292-3302 Gene denotes granzyme B Gene:3002
653 3478-3483 Gene denotes NKG2A Gene:3821
654 3821-3826 Gene denotes KLRC1 Gene:3821
655 3828-3833 Gene denotes NKG2A Gene:3821
656 3839-3844 Gene denotes KLRD1 Gene:3824
657 4439-4444 Gene denotes NKG2A Gene:3821
658 4446-4450 Gene denotes PD-1 Gene:5133
659 4803-4807 Gene denotes LAG3 Gene:3902
660 4812-4818 Gene denotes HAVCR2 Gene:84868
661 2803-2811 Species denotes patients Tax:9606
662 2938-2946 Species denotes patients Tax:9606
663 3373-3381 Species denotes patients Tax:9606
664 3403-3411 Species denotes patients Tax:9606
665 3627-3635 Species denotes patients Tax:9606
666 3660-3668 Species denotes patients Tax:9606
667 3736-3744 Species denotes patients Tax:9606
668 4076-4084 Species denotes patients Tax:9606
669 4099-4107 Species denotes patients Tax:9606
670 4116-4124 Species denotes patients Tax:9606
671 4142-4152 Species denotes SARS-CoV-2 Tax:2697049
672 4390-4398 Species denotes patients Tax:9606
673 4540-4548 Species denotes patients Tax:9606
674 4642-4650 Species denotes patients Tax:9606
675 4699-4707 Species denotes patients Tax:9606
676 4910-4918 Species denotes patients Tax:9606
677 5112-5122 Species denotes SARS-CoV-2 Tax:2697049
678 2794-2802 Disease denotes COVID-19 MESH:C000657245
679 2929-2937 Disease denotes COVID-19 MESH:C000657245
680 3198-3212 Disease denotes hyporesponsive MESH:C566417
681 3387-3401 Disease denotes active disease OMIM:612348
682 3428-3436 Disease denotes COVID-19 MESH:C000657245
683 3618-3626 Disease denotes COVID-19 MESH:C000657245
684 3651-3659 Disease denotes COVID-19 MESH:C000657245
685 4067-4075 Disease denotes COVID-19 MESH:C000657245
686 4089-4098 Disease denotes pneumonia MESH:D011014
687 4130-4134 Disease denotes ARDS MESH:D012128
688 4272-4281 Disease denotes pneumonia MESH:D011014
689 4286-4290 Disease denotes ARDS MESH:D012128
690 4404-4408 Disease denotes ARDS MESH:D012128
691 4531-4539 Disease denotes COVID-19 MESH:C000657245
692 4633-4641 Disease denotes COVID-19 MESH:C000657245
693 4720-4728 Disease denotes COVID-19 MESH:C000657245
694 4895-4909 Disease denotes CoV-2 infected MESH:C000657245
695 5101-5110 Disease denotes infection MESH:D007239
713 5204-5212 Species denotes patients Tax:9606
714 5231-5234 Species denotes CoV Tax:11118
715 5333-5341 Species denotes patients Tax:9606
716 5463-5471 Species denotes patients Tax:9606
717 5506-5514 Species denotes patients Tax:9606
718 5543-5564 Species denotes Mycoplasma pneumoniae Tax:2104
719 5737-5745 Species denotes patients Tax:9606
720 5839-5846 Species denotes patient Tax:9606
721 6140-6148 Species denotes patients Tax:9606
722 6181-6189 Species denotes patients Tax:9606
723 5634-5642 Species denotes patients Tax:9606
724 5653-5661 Species denotes SARS CoV Tax:694009
725 5515-5523 Disease denotes infected MESH:D007239
726 5911-5931 Disease denotes SARS-CoV-1 infection MESH:C000657245
727 6014-6025 Disease denotes lymphopenia MESH:D008231
728 6254-6263 Disease denotes infection MESH:D007239
729 6303-6314 Disease denotes lymphopenia MESH:D008231
739 6397-6405 Species denotes patients Tax:9606
740 6420-6424 Species denotes CoVs Tax:11118
741 6719-6727 Species denotes patients Tax:9606
742 6765-6770 Species denotes mouse Tax:10090
743 6406-6414 Disease denotes infected MESH:D007239
744 6618-6626 Disease denotes infected MESH:D007239
745 6690-6698 Disease denotes infected MESH:D007239
746 6710-6718 Disease denotes COVID-19 MESH:C000657245
747 6838-6850 Disease denotes CoV infected MESH:D018352
769 6910-6915 Gene denotes TGF-β Gene:7039
770 7083-7088 Gene denotes TGF-β Gene:7039
771 7224-7229 Gene denotes TGF-β Gene:7039
772 7305-7310 Gene denotes TGF-β Gene:7039
773 7002-7010 Species denotes patients Tax:9606
774 7104-7112 Species denotes patients Tax:9606
775 7354-7357 Species denotes CoV Tax:11118
776 7358-7366 Species denotes patients Tax:9606
777 7451-7459 Species denotes patients Tax:9606
778 7791-7798 Species denotes patient Tax:9606
779 7908-7915 Species denotes patient Tax:9606
780 6954-6980 Disease denotes NK cell hyporesponsiveness MESH:C566417
781 6993-7001 Disease denotes COVID-19 MESH:C000657245
782 7442-7450 Disease denotes COVID-19 MESH:C000657245
783 7486-7496 Disease denotes infections MESH:D007239
784 7508-7528 Disease denotes nosocomial pneumonia MESH:D003428
785 7532-7542 Disease denotes bacteremia MESH:D016470
786 7564-7584 Disease denotes SARS-CoV-2 infection MESH:C000657245
787 7681-7691 Disease denotes infections MESH:D007239
788 7782-7790 Disease denotes COVID-19 MESH:C000657245
789 7845-7865 Disease denotes secondary infections MESH:D060085
798 8746-8751 Gene denotes IFN-γ Gene:3458
799 8072-8080 Species denotes patients Tax:9606
800 8329-8339 Species denotes SARS-CoV-2 Tax:2697049
801 8957-8965 Species denotes patients Tax:9606
802 8020-8033 Disease denotes CoV infection MESH:D018352
803 8363-8378 Disease denotes viral infection MESH:D001102
804 8950-8956 Disease denotes cancer MESH:D009369
805 9042-9055 Disease denotes CoV infection MESH:D018352

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T29 1257-1264 Phenotype denotes viremia http://purl.obolibrary.org/obo/HP_0020071
T30 3251-3256 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T31 4089-4098 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T32 4272-4281 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T33 5554-5564 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T34 6014-6025 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T35 6303-6314 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T36 7519-7528 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T37 7532-7542 Phenotype denotes bacteremia http://purl.obolibrary.org/obo/HP_0031864
T38 8950-8956 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T66 469-493 http://purl.obolibrary.org/obo/GO_0002456 denotes cellular immune response
T67 469-493 http://purl.obolibrary.org/obo/GO_0002449 denotes cellular immune response
T68 469-493 http://purl.obolibrary.org/obo/GO_0002443 denotes cellular immune response
T69 478-493 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T70 640-653 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T71 843-860 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T72 843-860 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T73 3257-3265 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T74 3257-3265 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T75 3257-3265 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T76 3257-3265 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T77 6672-6686 http://purl.obolibrary.org/obo/GO_0016477 denotes cell migration
T78 7975-7993 http://purl.obolibrary.org/obo/GO_0030101 denotes NK cell activation
T79 7978-7993 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T80 8363-8378 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T81 9016-9038 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune response
T82 9023-9038 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

MyTest

Id Subject Object Predicate Lexical cue
32655581-15356152-34771676 412-415 15356152 denotes 119
32655581-19906920-34771677 608-611 19906920 denotes 120
32655581-15356152-34771678 1162-1165 15356152 denotes 119
32655581-15016880-34771679 1167-1170 15016880 denotes 121
32655581-15324552-34771680 1172-1175 15324552 denotes 122
32655581-17222058-34771681 1363-1366 17222058 denotes 123
32655581-15356152-34771682 1508-1511 15356152 denotes 119
32655581-15016880-34771683 1513-1516 15016880 denotes 121
32655581-15324552-34771683 1513-1516 15324552 denotes 121
32655581-17222058-34771683 1513-1516 17222058 denotes 121
32655581-32511406-34771684 2668-2671 32511406 denotes 126
32655581-32203188-34771685 2813-2816 32203188 denotes 127
32655581-32203188-34771686 3064-3067 32203188 denotes 127
32655581-32203188-34771687 3343-3346 32203188 denotes 127
32655581-32203188-34771688 3496-3499 32203188 denotes 127
32655581-32398875-34771689 3802-3805 32398875 denotes 128
32655581-32398875-34771690 3887-3890 32398875 denotes 128
32655581-32320677-34771691 4920-4923 32320677 denotes 131
32655581-15080302-34771692 5383-5386 15080302 denotes 132
32655581-32320677-34771693 5566-5569 32320677 denotes 131
32655581-15080302-34771694 5727-5730 15080302 denotes 132
32655581-15080302-34771695 6069-6072 15080302 denotes 132
32655581-15555395-34771696 6230-6233 15555395 denotes 133
32655581-23891402-34771697 6316-6318 23891402 denotes 42
32655581-23075143-34771698 6320-6323 23075143 denotes 134
32655581-25089913-34771698 6320-6323 25089913 denotes 134
32655581-28444873-34771698 6320-6323 28444873 denotes 134
32655581-32464098-34771699 6636-6639 32464098 denotes 137
32655581-19906920-34771700 6860-6863 19906920 denotes 120
32655581-15602737-34771701 7194-7197 15602737 denotes 138
32655581-15602737-34771702 7419-7422 15602737 denotes 138
32655581-15602737-34771703 7586-7589 15602737 denotes 138
32655581-30992245-34771704 7693-7696 30992245 denotes 139
32655581-28625834-34771705 8967-8970 28625834 denotes 140

TEST0

Id Subject Object Predicate Lexical cue
32655581-212-219-3171249 412-415 ["15356152"] denotes 119
32655581-190-197-3171250 608-611 ["19906920"] denotes 120
32655581-121-128-3171251 1162-1165 ["15356152"] denotes 119
32655581-126-133-3171252 1167-1170 ["15016880"] denotes 121
32655581-131-138-3171253 1172-1175 ["15324552"] denotes 122
32655581-185-192-3171254 1363-1366 ["17222058"] denotes 123
32655581-139-146-3171255 1508-1511 ["15356152"] denotes 119
32655581-144-151-3171256 1513-1516 ["15016880", "15324552", "17222058"] denotes 121
32655581-170-177-3171257 2668-2671 ["32511406"] denotes 126
32655581-139-146-3171258 2813-2816 ["32203188"] denotes 127
32655581-148-155-3171259 3064-3067 ["32203188"] denotes 127
32655581-235-242-3171260 3343-3346 ["32203188"] denotes 127
32655581-147-154-3171261 3496-3499 ["32203188"] denotes 127
32655581-232-239-3171262 3802-3805 ["32398875"] denotes 128
32655581-79-86-3171263 3887-3890 ["32398875"] denotes 128
32655581-94-101-3171264 4920-4923 ["32320677"] denotes 131
32655581-137-144-3171265 5383-5386 ["15080302"] denotes 132
32655581-177-184-3171266 5566-5569 ["32320677"] denotes 131
32655581-155-162-3171267 5727-5730 ["15080302"] denotes 132
32655581-186-193-3171268 6069-6072 ["15080302"] denotes 132
32655581-155-162-3171269 6230-6233 ["15555395"] denotes 133
32655581-80-86-3171270 6316-6318 ["23891402"] denotes 42
32655581-84-91-3171271 6320-6323 ["23075143", "25089913", "28444873"] denotes 134
32655581-192-199-3171272 6636-6639 ["32464098"] denotes 137
32655581-218-225-3171273 6860-6863 ["19906920"] denotes 120
32655581-182-189-3171274 7194-7197 ["15602737"] denotes 138
32655581-219-226-3171275 7419-7422 ["15602737"] denotes 138
32655581-161-168-3171276 7586-7589 ["15602737"] denotes 138
32655581-101-108-3171277 7693-7696 ["30992245"] denotes 139
32655581-234-241-3171278 8967-8970 ["28625834"] denotes 140

2_test

Id Subject Object Predicate Lexical cue
32655581-15356152-34771676 412-415 15356152 denotes 119
32655581-19906920-34771677 608-611 19906920 denotes 120
32655581-15356152-34771678 1162-1165 15356152 denotes 119
32655581-15016880-34771679 1167-1170 15016880 denotes 121
32655581-15324552-34771680 1172-1175 15324552 denotes 122
32655581-17222058-34771681 1363-1366 17222058 denotes 123
32655581-15356152-34771682 1508-1511 15356152 denotes 119
32655581-15016880-34771683 1513-1516 15016880 denotes 121
32655581-15324552-34771683 1513-1516 15324552 denotes 121
32655581-17222058-34771683 1513-1516 17222058 denotes 121
32655581-32511406-34771684 2668-2671 32511406 denotes 126
32655581-32203188-34771685 2813-2816 32203188 denotes 127
32655581-32203188-34771686 3064-3067 32203188 denotes 127
32655581-32203188-34771687 3343-3346 32203188 denotes 127
32655581-32203188-34771688 3496-3499 32203188 denotes 127
32655581-32398875-34771689 3802-3805 32398875 denotes 128
32655581-32398875-34771690 3887-3890 32398875 denotes 128
32655581-32320677-34771691 4920-4923 32320677 denotes 131
32655581-15080302-34771692 5383-5386 15080302 denotes 132
32655581-32320677-34771693 5566-5569 32320677 denotes 131
32655581-15080302-34771694 5727-5730 15080302 denotes 132
32655581-15080302-34771695 6069-6072 15080302 denotes 132
32655581-15555395-34771696 6230-6233 15555395 denotes 133
32655581-23891402-34771697 6316-6318 23891402 denotes 42
32655581-23075143-34771698 6320-6323 23075143 denotes 134
32655581-25089913-34771698 6320-6323 25089913 denotes 134
32655581-28444873-34771698 6320-6323 28444873 denotes 134
32655581-32464098-34771699 6636-6639 32464098 denotes 137
32655581-19906920-34771700 6860-6863 19906920 denotes 120
32655581-15602737-34771701 7194-7197 15602737 denotes 138
32655581-15602737-34771702 7419-7422 15602737 denotes 138
32655581-15602737-34771703 7586-7589 15602737 denotes 138
32655581-30992245-34771704 7693-7696 30992245 denotes 139
32655581-28625834-34771705 8967-8970 28625834 denotes 140

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T112 0-53 Sentence denotes NK Cell Role in Clearing Acute Coronavirus Infections
T113 54-199 Sentence denotes There is currently a paucity of studies into the role of NK cells not only in COVID-19 pathophysiology, but also in other coronavirus infections.
T114 200-417 Sentence denotes An in vivo study reported that beige mice on a B6 background cleared SARS-CoV-1 normally, indicating that functional lymphocytes, including NK cells, may not be required to eliminate SARS-CoV-1 in murine models (119).
T115 418-695 Sentence denotes However, in a more recent study characterizing the cellular immune response to SARS-CoV-1 in 12–14-month old BALB/c mice, T cell depletion did not prevent control of SARS-CoV-1 replication (120), suggesting a role for the innate immune system, and NK cells, in viral clearance.
T116 696-953 Sentence denotes Importantly, in this study CD4-depletion resulted in enhanced lung immunopathology and delayed viral clearance, while CD8-depletion did not affect viral replication or clearance, thus highlighting an important role for CD4+ T cells in coronavirus infection.
T117 954-1040 Sentence denotes These conflicting results may be due to the inherent limitations of CoV murine models.
T118 1041-1177 Sentence denotes In 4–8 week-old mice, SARS-CoV-1 is associated only with mild pneumonitis and cytokines are not detectable in the lungs (119, 121, 122).
T119 1178-1368 Sentence denotes A SARS-CoV-1 isolate (MA-15) replicates to a high titer and is associated with viremia and mortality, however the model lacks significant inflammatory cell infiltration into the lungs (123).
T120 1369-1522 Sentence denotes Thus, mouse models developed for the study of SARS fell short in terms of reproducing the clinical and histopathological signs of disease (119, 121–123).
T121 1523-1666 Sentence denotes It is therefore necessary to develop a usable animal model that is capable of reproducing the clinical and histopathological signs on COVID-19.
T122 1667-1879 Sentence denotes Israelow et al. recently described a SARS-CoV-2 murine model based on adeno associated virus (AAV)9-mediated expression of human (h)ACE2, which replicated the pathologic findings found in COVID-19 patients (124).
T123 1880-2057 Sentence denotes This model, which overcame the inability of murine (m)ACE2 to support SARS-CoV-2 infection, was used to show the inability of Type I IFN to control SARS-CoV-2 replication (124).
T124 2058-2356 Sentence denotes In a similar attempt to overcome the lack of infectability through mACE2, Dinnon et al. recently described a recombinant virus (SARS-CoV-2 MA) with a remodeled S protein mACE2 interface, which replicated in upper and lower airways in young and aged mice with disease being more severe in aged mice.
T125 2357-2497 Sentence denotes The authors used this model to screen therapeutics from vaccine challenge studies and assessed pegylated IFN-λ-1 as a promising therapeutic.
T126 2498-2673 Sentence denotes The authors suggested that this model has greater ease of use, cost, and utility over transgenic hACE2 models (125) to evaluate vaccine and therapeutic efficacy in mice (126).
T127 2674-2818 Sentence denotes A preliminary analysis of NK cell function and phenotype has been performed by Zheng et al. using peripheral blood from COVID-19 patients (127).
T128 2819-2915 Sentence denotes On admission, NK cell levels in the peripheral blood inversely correlated with disease severity.
T129 2916-3069 Sentence denotes Furthermore, COVID-19 patients with severe disease had significantly lower numbers of circulating NK cells, as compared to mild disease (p < 0.05) (127).
T130 3070-3348 Sentence denotes Additionally, circulating NK cells in severe disease displayed increased expression of the inhibitory receptor NKG2A and had an hyporesponsive phenotype with lower levels of IFN-γ, tumor necrosis factor (TNF)-α, IL-2, and granzyme B, although degranulation was maintained (127).
T131 3349-3501 Sentence denotes Finally, as compared to patients with active disease, patients recovering from COVID-19 had higher numbers of NK cells and lower NKG2A expression (127).
T132 3502-3807 Sentence denotes Liao et al. performed single-cell RNAseq on the cells obtained from bronchoalveolar lavage fluid of severe and mild COVID-19 patients and found that COVID-19 patients had significantly more NK cell infiltrates into the lungs, however patients with severe disease had reduced proportions of NK cells (128).
T133 3808-3892 Sentence denotes In addition, KLRC1 (NKG2A) and KLRD1 (CD94) were highly expressed by NK cells (128).
T134 3893-4327 Sentence denotes Carvelli et al. analyzed myeloid and lymphoid populations by immunophenotyping from blood and bronchoalveolar lavage fluid (BALF) in 10 healthy controls, 10 paucisymptomatic COVID-19 patients, 34 pneumonia patients, and 28 patients with ARDS due to SARS-CoV-2 and found that absolute numbers of peripheral blood lymphocytes, including NK cells, were significantly reduced in the pneumonia and ARDS groups compared to healthy controls.
T135 4328-4467 Sentence denotes Furthermore, the proportion of mature NK cells was reduced in patients with ARDS and NK cells showed increased NKG2A, PD-1, and CD39 (129).
T136 4468-4729 Sentence denotes Finally, Wilk et al. performed single-cell RNA-sequencing on 7 COVID-19 patients and 6 healthy controls and found that the CD56bright population was depleted in all COVID-19 patients but the CD56dim population was depleted only in patients with severe COVID-19.
T137 4730-4825 Sentence denotes Furthermore, NK cells had increased expression of the exhaustion markers LAG3 and HAVCR2 (130).
T138 4826-4925 Sentence denotes NK cell cytopenia seems to be a consistent characteristic among SARS-CoV-2 infected patients (131).
T139 4926-5160 Sentence denotes Altogether, these data indicate alterations in the NK cell phenotype and functional profile that are consistent with the hypothesis that to establish a productive and lasting infection, SARS-CoV-2 needs to dampen the NK cell response.
T140 5161-5245 Sentence denotes NK cell dysfunctions were also observed in patients from the previous CoV outbreaks.
T141 5246-5388 Sentence denotes Wang et al. assessed NK cell number and phenotype using peripheral blood from 221 SARS patients admitted to hospitals in Beijing, China (132).
T142 5389-5571 Sentence denotes NK cell proportion and absolute number were significantly reduced in SARS patients as compared to healthy donors and patients infected with the bacterium Mycoplasma pneumoniae (131).
T143 5572-5732 Sentence denotes NK cell number correlated inversely with disease severity and patients with anti-SARS CoV-specific IgG or IgM antibodies had significantly fewer NK cells (132).
T144 5733-5882 Sentence denotes The patients assessed had varied disease duration from 4 to 72 days (mean 31.7 days) and this allowed for patient stratification by disease duration.
T145 5883-6074 Sentence denotes Within the first 10 days of SARS-CoV-1 infection, NK cell numbers remained high but this period was followed by the development of lymphopenia with levels recovering only around day 40 (132).
T146 6075-6235 Sentence denotes Dong et al. also observed a reduction of NK cell numbers in SARS patients, and these levels were lower in patients with severe, as compared to mild, SARS (133).
T147 6236-6329 Sentence denotes In addition, MERS infection is strongly associated with leuko- and lymphopenia (42, 134–136).
T148 6330-6443 Sentence denotes The mechanisms underlying the reduction of circulating NK cells in patients infected with CoVs are still unclear.
T149 6444-6641 Sentence denotes As most studies have focused on peripheral blood NK cells, it is possible that the reduced number of circulating NK cells is due to redistribution of blood NK cells into the infected tissues (137).
T150 6642-6865 Sentence denotes While it is hard to assess NK cell migration to infected tissues in COVID-19 patients, this hypothesis was corroborated by mouse studies, where NK cells have been shown to migrate to the lungs in CoV infected animals (120).
T151 6866-7011 Sentence denotes An abundance of inhibitory factors, such as TGF-β, may be partially responsible for the NK cell hyporesponsiveness observed in COVID-19 patients.
T152 7012-7199 Sentence denotes In support of this hypothesis, Huang et al. found significantly higher TGF-β levels in SARS patients compared to healthy controls and this positively correlated with length of stay (138).
T153 7200-7424 Sentence denotes Given the importance of TGF-β in suppressing NK cell functions, it is possible that the higher levels of TGF-β (as well as other inhibitory cytokines) in CoV patients leads to suppression of NK cell antiviral activity (138).
T154 7425-7591 Sentence denotes Early studies of COVID-19 patients report secondary (super-) infections, including nosocomial pneumonia or bacteremia as a complication of SARS-CoV-2 infection (138).
T155 7592-7925 Sentence denotes Since NK cells are critical first responders that play a role in preventing and clearing infections (139), a poor NK cell count or exhausted phenotype, in addition to negatively influencing COVID-19 patient outcomes, could facilitate the development of secondary infections and have a significant negative impact on patient outcomes.
T156 7926-8227 Sentence denotes One of the main barriers in studying the role of NK cell activation in the early clearance of CoV infection in asymptomatic or mildly symptomatic patients is the fact that these individuals are rarely diagnosed in the clinic and therefore an opportunity to collect samples for research does not exist.
T157 8228-8444 Sentence denotes Thus, while there is currently no direct evidence to support a role for NK cells in the clearance of SARS-CoV-2, evidence showing that viral infection has a negative effect on the NK cell compartment is accumulating.
T158 8445-8972 Sentence denotes Given the importance of NK cell activity in early viral clearance and late immunopathology, having a rapid and reliable test to predict NK cell function, such as NKVue™ (ATGen Canada/NKMax), whereby whole blood is stimulated by an NK cell-specific activating cytokine mix and activity is measured via IFN-γ production, might allow researchers to predict who will mount an adequate response with asymptomatic or minimally symptomatic viral clearance and who will need ICU admission, as has been shown with cancer patients (140).
T159 8973-9122 Sentence denotes Further research will be required into the innate immune response to CoV infection to more fully understand NK cell contributions to viral clearance.