PMC:7321036 / 829-1160 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T19","span":{"begin":21,"end":26},"obj":"CHEBI:23888;CHEBI:23888"},{"id":"T20","span":{"begin":31,"end":40},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T21","span":{"begin":103,"end":115},"obj":"GO:0065007"},{"id":"T22","span":{"begin":147,"end":160},"obj":"CHEBI:52217;CHEBI:52217"},{"id":"T23","span":{"begin":179,"end":182},"obj":"PR:000008220"},{"id":"T24","span":{"begin":273,"end":281},"obj":"SP_7"},{"id":"T33194","span":{"begin":21,"end":26},"obj":"CHEBI:23888;CHEBI:23888"},{"id":"T59691","span":{"begin":31,"end":40},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T77793","span":{"begin":103,"end":115},"obj":"GO:0065007"},{"id":"T44088","span":{"begin":147,"end":160},"obj":"CHEBI:52217;CHEBI:52217"},{"id":"T2452","span":{"begin":179,"end":182},"obj":"PR:000008220"},{"id":"T31032","span":{"begin":273,"end":281},"obj":"SP_7"}],"text":"ticles. Eighty-seven drugs and compounds were identified by mapping global phosphorylation profiles to dysregulated kinases and pathways. We found pharmacologic inhibition of the p38, CK2, CDK, AXL, and PIKFYVE kinases to possess antiviral efficacy, representing potential COVID-19 therapies.\n\nGraphical Abstract\n\nHighlights\n• Pho"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T13","span":{"begin":273,"end":281},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"ticles. Eighty-seven drugs and compounds were identified by mapping global phosphorylation profiles to dysregulated kinases and pathways. We found pharmacologic inhibition of the p38, CK2, CDK, AXL, and PIKFYVE kinases to possess antiviral efficacy, representing potential COVID-19 therapies.\n\nGraphical Abstract\n\nHighlights\n• Pho"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T4","span":{"begin":21,"end":26},"obj":"Chemical"},{"id":"T5","span":{"begin":230,"end":239},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"ticles. Eighty-seven drugs and compounds were identified by mapping global phosphorylation profiles to dysregulated kinases and pathways. We found pharmacologic inhibition of the p38, CK2, CDK, AXL, and PIKFYVE kinases to possess antiviral efficacy, representing potential COVID-19 therapies.\n\nGraphical Abstract\n\nHighlights\n• Pho"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T37166","span":{"begin":75,"end":90},"obj":"http://purl.obolibrary.org/obo/GO_0016310"}],"text":"ticles. Eighty-seven drugs and compounds were identified by mapping global phosphorylation profiles to dysregulated kinases and pathways. We found pharmacologic inhibition of the p38, CK2, CDK, AXL, and PIKFYVE kinases to possess antiviral efficacy, representing potential COVID-19 therapies.\n\nGraphical Abstract\n\nHighlights\n• Pho"}

{"project":"LitCovid-PubTator","denotations":[{"id":"18","span":{"begin":179,"end":182},"obj":"Gene"},{"id":"19","span":{"begin":194,"end":197},"obj":"Gene"},{"id":"30","span":{"begin":273,"end":281},"obj":"Disease"}],"attributes":[{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"Gene:5594"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"Gene:558"},{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ticles. Eighty-seven drugs and compounds were identified by mapping global phosphorylation profiles to dysregulated kinases and pathways. We found pharmacologic inhibition of the p38, CK2, CDK, AXL, and PIKFYVE kinases to possess antiviral efficacy, representing potential COVID-19 therapies.\n\nGraphical Abstract\n\nHighlights\n• Pho"}

{"project":"LitCovid-sentences","denotations":[{"id":"T7","span":{"begin":8,"end":137},"obj":"Sentence"},{"id":"T8","span":{"begin":138,"end":292},"obj":"Sentence"},{"id":"T9","span":{"begin":294,"end":312},"obj":"Sentence"},{"id":"T10","span":{"begin":314,"end":324},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ticles. Eighty-seven drugs and compounds were identified by mapping global phosphorylation profiles to dysregulated kinases and pathways. We found pharmacologic inhibition of the p38, CK2, CDK, AXL, and PIKFYVE kinases to possess antiviral efficacy, representing potential COVID-19 therapies.\n\nGraphical Abstract\n\nHighlights\n• Pho"}