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PMC:7321036 / 79169-101418 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T183 5716-5865 SO:0001811 denotes p control was set to All. For phosphopeptide enriched samples, data were collected using a resolving power of 30,000 and a maximum ion injection time
T184 5957-6011 NCBITaxon:9527 denotes maximum ion injection time of 22 ms. Spectral library
T185 6039-6265 NCBITaxon:6073 denotes cessing Raw mass spectrometry data from each DDA dataset were used to build separate libraries for DIA searches using the Pulsar search engine integrated into Spectronaut version 13.12.200217.43655 (Bruderer et al., 2015) by s
T186 6279-6315 NCBITaxon:9606 denotes st a database of Uniprot Chlorocebus
T187 6422-6472 SP_6;NCBITaxon:9606 denotes genomic sequence downloaded from GISAID (accession
T188 6535-6596 SO:0000704 denotes G22661T Spike V367F and G26144T ORF3a G251V) detected by RNAS
T189 8951-8974 NCBITaxon:10239 denotes V-2 infected Caco-2 cel
T190 9339-9345 CHEBI:24870;CHEBI:24870 denotes ilicon
T191 11416-11428 SO:0000704 denotes were transfe
T192 12046-12214 GO:0065007 denotes r pLVX-TetOne-Puro empty vector. 48 hours post transduction, 10 μg/mL Puromycin was added to cultures to select transduced cells. Polyclonal stable cell lines were seed
T193 13152-13200 GO:0065007 denotes ro E6 cells were seeded per sample. The followin
T194 13999-14059 GO:0065007 denotes rsus SSC-H plot. Next, typical cellular morphology was gated
T195 14064-14105 SO:0000704 denotes g a FSC-A versus SSC-A plot. These single
T196 15224-15255 SO:0000704 denotes g oligo (dT) primers and SuperS
T197 15719-15723 SO:0000704 denotes gene
T198 17327-17437 GO:0065007 denotes reater than those indicated, including a DMSO control. Plates were then transferred into the BSL-3 facility an
T199 18223-18402 SO:0000855 denotes ound) ∗100 and the DMSO control was then set to 100% infection for analysis. The IC50 for each experiment was determined using the Prism software (GraphPad). For select inhibitors
T200 19800-20041 SO:0001811 denotes pool, using Lipofectamine RNAiMAX (Thermo Fisher Scientific) according to the manufacturer’s instructions. Twenty-four (24) hours post transfection, the cell culture supernatant was removed and replaced with virus inoculum (MOI of 0.1 PFU/ce

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 20496-20503 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T2 20638-20642 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T3 21025-21032 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T4 21124-21127 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T5 21254-21259 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T6 21320-21325 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T7 21386-21391 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T8 21814-21818 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T9 21863-21867 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T10 21900-21905 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T11 21955-21959 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T12 22149-22154 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T13 22176-22181 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T601 25-29 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T602 71-76 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T603 101-106 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T604 140-145 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T605 217-222 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T606 449-453 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T607 474-479 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T608 696-704 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T609 722-726 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T610 853-860 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T611 904-912 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T612 1175-1178 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T613 1348-1355 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T614 2369-2376 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T615 4624-4628 Body_part denotes lens http://purl.org/sig/ont/fma/fma58241
T616 5253-5260 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T617 5525-5529 Body_part denotes lens http://purl.org/sig/ont/fma/fma58241
T618 5876-5883 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T619 6334-6342 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T620 6388-6395 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T621 6629-6636 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T622 6732-6742 Body_part denotes methionine http://purl.org/sig/ont/fma/fma82759
T623 6793-6801 Body_part denotes cysteine http://purl.org/sig/ont/fma/fma82751
T624 6908-6915 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T625 7148-7155 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T626 7483-7488 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T627 7596-7601 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T628 7670-7675 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T629 7864-7868 Body_part denotes calf http://purl.org/sig/ont/fma/fma24984
T630 7869-7874 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T631 7995-8002 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T632 8065-8072 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T633 8162-8167 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T634 8677-8682 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T635 8898-8905 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T636 8971-8976 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T637 9010-9017 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T638 9178-9183 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T639 9238-9243 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T640 9476-9481 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T641 11043-11048 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T642 11055-11062 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T643 11378-11383 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T644 11504-11507 Body_part denotes Gag http://purl.org/sig/ont/fma/fma63011
T645 11893-11898 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T646 12169-12174 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T647 12194-12198 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T648 12300-12305 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T649 12373-12377 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T650 12557-12564 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T651 12670-12675 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T652 13124-13128 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T653 13158-13163 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T654 13206-13211 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T655 13377-13382 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T656 13413-13418 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T657 13522-13527 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T658 13641-13646 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T659 13778-13782 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T660 13979-13984 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T661 14225-14230 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T662 14245-14253 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T663 14295-14300 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T664 14421-14426 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T665 14613-14618 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T666 14683-14692 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T667 14697-14707 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T668 14713-14716 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T669 14727-14732 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T670 14764-14767 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T671 14821-14824 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T672 14909-14916 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T673 14933-14937 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T674 15028-15036 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T675 15054-15058 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T676 15082-15091 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T677 15194-15197 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T678 15574-15577 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T679 15901-15909 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T680 15943-15948 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T681 15971-15980 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T682 15981-15991 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T683 16114-16119 Body_part denotes CCL11 http://purl.org/sig/ont/fma/fma241992
T684 16120-16127 Body_part denotes Eotaxin http://purl.org/sig/ont/fma/fma241992
T685 16239-16243 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T686 16246-16250 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T687 16328-16331 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T688 16401-16409 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T689 16438-16446 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T690 16592-16600 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T691 17023-17031 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T692 17121-17126 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T693 17668-17673 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T694 17771-17776 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T695 17818-17825 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T696 17917-17922 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T697 17942-17947 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T698 18076-18083 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T699 18114-18119 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T700 18196-18201 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T701 18208-18213 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T702 18483-18489 Body_part denotes Tissue http://purl.org/sig/ont/fma/fma9637
T703 18718-18723 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T704 18742-18747 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T705 18788-18793 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T706 18968-18972 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T707 19081-19085 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T708 19284-19289 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T709 19536-19541 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T710 19565-19570 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T711 19647-19652 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T712 19669-19674 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T713 19953-19957 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T714 20039-20043 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T715 20257-20261 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T716 20349-20356 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T26 217-222 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T27 7869-7874 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T28 9191-9194 Body_part denotes tip http://purl.obolibrary.org/obo/UBERON_2001840
T29 18483-18489 Body_part denotes Tissue http://purl.obolibrary.org/obo/UBERON_0000479
T30 21386-21391 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T339 30-39 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T340 189-197 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T341 5379-5382 Disease denotes DIA http://purl.obolibrary.org/obo/MONDO_0022963
T342 5610-5613 Disease denotes DIA http://purl.obolibrary.org/obo/MONDO_0022963
T343 6138-6141 Disease denotes DIA http://purl.obolibrary.org/obo/MONDO_0022963
T344 6377-6385 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T345 6693-6696 Disease denotes BGS http://purl.obolibrary.org/obo/MONDO_0009039
T346 6982-6985 Disease denotes BGS http://purl.obolibrary.org/obo/MONDO_0009039
T347 7134-7137 Disease denotes DIA http://purl.obolibrary.org/obo/MONDO_0022963
T348 7183-7186 Disease denotes BGS http://purl.obolibrary.org/obo/MONDO_0009039
T349 7376-7379 Disease denotes DIA http://purl.obolibrary.org/obo/MONDO_0022963
T350 7535-7543 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T351 7660-7669 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T352 7973-7981 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T353 8039-8047 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T354 8944-8952 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T355 9302-9310 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T356 11101-11109 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T357 11258-11266 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T358 12024-12032 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T359 12642-12650 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T360 12918-12920 Disease denotes EV http://purl.obolibrary.org/obo/MONDO_0009176
T361 13054-13069 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T362 13060-13069 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T363 13255-13263 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T364 13836-13838 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T365 14190-14198 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T366 14201-14214 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T367 14446-14454 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T368 14571-14580 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T369 15103-15111 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T370 16987-16995 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T371 17204-17213 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T372 17450-17458 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T373 17627-17636 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T374 18157-18166 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T375 18276-18285 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T376 18443-18453 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T377 18498-18508 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T378 18539-18549 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T379 18595-18604 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T380 18642-18652 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T381 18814-18822 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T382 19170-19173 Disease denotes MTT http://purl.obolibrary.org/obo/MONDO_0016757
T383 20235-20244 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T384 20380-20388 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T385 20594-20602 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T386 21182-21190 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 20638-20642 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T2 21102-21103 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 21141-21142 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 21160-21161 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 21246-21259 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T6 21293-21294 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 21320-21325 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8 21492-21493 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 21553-21556 http://purl.obolibrary.org/obo/CLO_0050644 denotes w/v
T10 21608-21609 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 21814-21818 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T12 21863-21867 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T13 21900-21905 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T14 21955-21959 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T15 22058-22059 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 22149-22154 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T17 22176-22181 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1108 17-29 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cell
T1109 63-76 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1110 101-106 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1111 140-145 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1112 203-204 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1113 449-453 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T1114 474-479 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T1115 593-598 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1116 667-672 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1117 722-726 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1118 1144-1145 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1119 1302-1303 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1120 1455-1456 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1121 1753-1754 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1122 1819-1820 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1123 1980-1981 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1124 2089-2098 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T1125 2127-2130 http://purl.obolibrary.org/obo/CLO_0001655 denotes ACN
T1126 2241-2246 http://purl.obolibrary.org/obo/CLO_0053794 denotes 4 × 1
T1127 2307-2310 http://purl.obolibrary.org/obo/CLO_0001655 denotes ACN
T1128 2631-2634 http://purl.obolibrary.org/obo/CLO_0001562 denotes a 2
T1129 2631-2634 http://purl.obolibrary.org/obo/CLO_0001563 denotes a 2
T1130 2952-2953 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1131 3016-3019 http://purl.obolibrary.org/obo/CLO_0001655 denotes ACN
T1132 3048-3056 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1133 3081-3084 http://purl.obolibrary.org/obo/CLO_0001655 denotes ACN
T1134 3227-3230 http://purl.obolibrary.org/obo/CLO_0001655 denotes ACN
T1135 3493-3496 http://purl.obolibrary.org/obo/CLO_0001655 denotes ACN
T1136 3776-3777 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1137 3861-3862 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1138 3959-3960 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1139 4000-4001 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T1140 4027-4030 http://purl.obolibrary.org/obo/CLO_0001655 denotes ACN
T1141 4032-4040 http://purl.obolibrary.org/obo/PR_000018263 denotes Peptides
T1142 4062-4069 http://purl.obolibrary.org/obo/OBI_0100026 denotes organic
T1143 4062-4069 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organic
T1144 4107-4108 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T1145 4157-4158 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T1146 4193-4194 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T1147 4213-4214 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1148 4306-4307 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1149 4318-4319 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1150 4404-4405 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1151 4486-4487 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1152 4503-4504 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1153 4585-4586 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1154 4624-4628 http://purl.obolibrary.org/obo/UBERON_0005389 denotes lens
T1155 4649-4650 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1156 4684-4686 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T1157 4734-4738 http://purl.obolibrary.org/obo/CLO_0001550 denotes a 10
T1158 4768-4776 http://purl.obolibrary.org/obo/PR_000018263 denotes Peptides
T1159 4818-4820 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1160 4821-4823 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1161 4898-4900 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1162 4901-4903 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1163 4958-4960 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1164 4961-4963 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1165 5100-5101 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1166 5133-5137 http://purl.obolibrary.org/obo/CLO_0001599 denotes a 54
T1167 5138-5140 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T1168 5280-5282 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1169 5283-5285 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1170 5316-5317 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1171 5318-5320 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T1172 5321-5323 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T1173 5417-5419 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T1174 5456-5457 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1175 5486-5487 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1176 5525-5529 http://purl.obolibrary.org/obo/UBERON_0005389 denotes lens
T1177 5550-5551 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1178 5581-5583 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T1179 5671-5672 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1180 5708-5710 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T1181 5805-5806 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1182 5837-5838 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1183 5872-5874 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T1184 5923-5924 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1185 5955-5956 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1186 5987-5989 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T1187 5990-5992 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T1188 6282-6283 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1189 6611-6616 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1190 6820-6821 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1191 6865-6872 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1192 6874-6881 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1193 6898-6901 http://purl.obolibrary.org/obo/UBERON_0003059 denotes PSM
T1194 7039-7043 http://purl.obolibrary.org/obo/CLO_0009141 denotes S, T
T1195 7039-7043 http://purl.obolibrary.org/obo/CLO_0050980 denotes S, T
T1196 7054-7055 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1197 7476-7482 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T1198 7476-7482 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T1199 7476-7482 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T1200 7476-7482 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T1201 7483-7488 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1202 7588-7601 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1203 7670-7675 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1204 7864-7868 http://www.ebi.ac.uk/efo/EFO_0003051 denotes calf
T1205 7982-7990 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T1206 8162-8167 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1207 8194-8201 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T1208 8202-8206 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T1209 8251-8258 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T1210 8259-8263 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T1211 8269-8274 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T1212 8343-8350 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T1213 8450-8451 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1214 8516-8517 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1215 8534-8543 http://purl.obolibrary.org/obo/BFO_0000030 denotes objective
T1216 8677-8682 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1217 8964-8970 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T1218 8964-8970 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T1219 8964-8970 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T1220 8964-8970 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T1221 8971-8976 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1222 9230-9243 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1223 9476-9481 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1224 9970-9971 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1225 10072-10073 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1226 10231-10233 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T1227 10234-10235 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T1228 10250-10251 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1229 10357-10358 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1230 10375-10380 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T1231 10622-10625 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4°C
T1232 10775-10776 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1233 10783-10786 http://purl.obolibrary.org/obo/CLO_0009477 denotes UC7
T1234 10852-10853 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1235 10858-10860 http://purl.obolibrary.org/obo/CLO_0002040 denotes BT
T1236 10936-10943 http://www.ebi.ac.uk/efo/EFO_0000881 denotes Digital
T1237 10970-10971 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1238 11035-11048 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1239 11378-11383 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1240 11402-11403 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1241 11646-11647 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1242 11731-11734 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4°C
T1243 11802-11803 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1244 11885-11898 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1245 12079-12081 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T1246 12169-12174 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1247 12194-12204 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T1248 12290-12292 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T1249 12300-12305 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T1250 12373-12377 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T1251 12662-12675 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1252 12985-12987 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T1253 12997-13005 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1254 13124-13128 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T1255 13150-13163 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1256 13206-13211 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1257 13377-13382 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1258 13413-13418 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T1259 13522-13527 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T1260 13641-13646 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1261 13778-13782 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1262 13856-13857 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1263 13979-13984 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1264 13995-13996 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1265 14066-14067 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1266 14072-14073 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1267 14085-14086 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1268 14176-14178 http://purl.obolibrary.org/obo/CLO_0003414 denotes G2
T1269 14220-14224 http://purl.obolibrary.org/obo/CLO_0001601 denotes A549
T1270 14220-14224 http://purl.obolibrary.org/obo/CLO_0050025 denotes A549
T1271 14220-14224 http://purl.obolibrary.org/obo/CLO_0054264 denotes A549
T1272 14220-14224 http://purl.obolibrary.org/obo/CLO_0054265 denotes A549
T1273 14220-14224 http://purl.obolibrary.org/obo/CLO_0054266 denotes A549
T1274 14220-14224 http://purl.obolibrary.org/obo/CLO_0054267 denotes A549
T1275 14220-14224 http://purl.obolibrary.org/obo/CLO_0054268 denotes A549
T1276 14220-14224 http://purl.obolibrary.org/obo/CLO_0054269 denotes A549
T1277 14225-14230 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1278 14285-14289 http://purl.obolibrary.org/obo/CLO_0001601 denotes A549
T1279 14285-14289 http://purl.obolibrary.org/obo/CLO_0050025 denotes A549
T1280 14285-14289 http://purl.obolibrary.org/obo/CLO_0054264 denotes A549
T1281 14285-14289 http://purl.obolibrary.org/obo/CLO_0054265 denotes A549
T1282 14285-14289 http://purl.obolibrary.org/obo/CLO_0054266 denotes A549
T1283 14285-14289 http://purl.obolibrary.org/obo/CLO_0054267 denotes A549
T1284 14285-14289 http://purl.obolibrary.org/obo/CLO_0054268 denotes A549
T1285 14285-14289 http://purl.obolibrary.org/obo/CLO_0054269 denotes A549
T1286 14295-14300 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1287 14421-14426 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1288 14613-14618 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1289 14727-14732 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1290 14933-14937 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1291 15054-15058 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T1292 15453-15454 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1293 15471-15481 http://purl.obolibrary.org/obo/OBI_0000968 denotes Instrument
T1294 15719-15724 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T1295 15943-15948 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T28393 15968-15970 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T1297 16200-16204 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T1298 16303-16308 http://purl.obolibrary.org/obo/CLO_0053703 denotes IL-16
T1299 16321-16323 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T1300 16458-16461 http://purl.obolibrary.org/obo/CLO_0008693 denotes R&D
T1301 16458-16461 http://purl.obolibrary.org/obo/CLO_0008770 denotes R&D
T1302 16703-16704 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1303 16750-16751 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1304 16937-16938 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1305 16959-16960 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1306 17113-17126 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1307 17366-17367 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1308 17603-17605 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T1309 17668-17673 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1310 17771-17776 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1311 17815-17817 http://purl.obolibrary.org/obo/CLO_0008192 denotes NP
T1312 17887-17888 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1313 17917-17922 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1314 17942-17947 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1315 18073-18075 http://purl.obolibrary.org/obo/CLO_0008192 denotes NP
T1316 18106-18119 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1317 18196-18201 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1318 18208-18213 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1319 18581-18583 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T1320 18710-18723 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1321 18734-18747 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1322 18788-18793 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1323 18968-18972 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1324 19081-19085 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1325 19276-19289 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T1326 19531-19535 http://purl.obolibrary.org/obo/CLO_0001601 denotes A549
T1327 19531-19535 http://purl.obolibrary.org/obo/CLO_0050025 denotes A549
T1328 19531-19535 http://purl.obolibrary.org/obo/CLO_0054264 denotes A549
T1329 19531-19535 http://purl.obolibrary.org/obo/CLO_0054265 denotes A549
T1330 19531-19535 http://purl.obolibrary.org/obo/CLO_0054266 denotes A549
T1331 19531-19535 http://purl.obolibrary.org/obo/CLO_0054267 denotes A549
T1332 19531-19535 http://purl.obolibrary.org/obo/CLO_0054268 denotes A549
T1333 19531-19535 http://purl.obolibrary.org/obo/CLO_0054269 denotes A549
T1334 19536-19541 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1335 19565-19570 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1336 19637-19641 http://purl.obolibrary.org/obo/CLO_0001601 denotes A549
T1337 19637-19641 http://purl.obolibrary.org/obo/CLO_0050025 denotes A549
T1338 19637-19641 http://purl.obolibrary.org/obo/CLO_0054264 denotes A549
T1339 19637-19641 http://purl.obolibrary.org/obo/CLO_0054265 denotes A549
T1340 19637-19641 http://purl.obolibrary.org/obo/CLO_0054266 denotes A549
T1341 19637-19641 http://purl.obolibrary.org/obo/CLO_0054267 denotes A549
T1342 19637-19641 http://purl.obolibrary.org/obo/CLO_0054268 denotes A549
T1343 19637-19641 http://purl.obolibrary.org/obo/CLO_0054269 denotes A549
T1344 19647-19652 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1345 19669-19674 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1346 19698-19700 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T1347 19953-19957 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1348 20008-20013 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1349 20039-20043 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1350 20056-20057 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1351 20089-20094 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1352 20257-20261 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T356 779-787 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T357 853-860 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T358 904-912 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T359 939-945 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T360 951-955 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T361 964-972 Chemical denotes ammonium http://purl.obolibrary.org/obo/CHEBI_28938
T362 986-989 Chemical denotes ABC http://purl.obolibrary.org/obo/CHEBI_421707
T363 999-1003 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T364 1005-1023 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T366 1014-1023 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T367 1063-1073 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T368 1093-1097 Chemical denotes Tris http://purl.obolibrary.org/obo/CHEBI_9754
T369 1099-1113 Chemical denotes 2-carboxyethyl http://purl.obolibrary.org/obo/CHEBI_50329
T370 1114-1123 Chemical denotes phosphine http://purl.obolibrary.org/obo/CHEBI_30278|http://purl.obolibrary.org/obo/CHEBI_35883
T372 1125-1129 Chemical denotes TCEP http://purl.obolibrary.org/obo/CHEBI_63213
T373 1175-1178 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T374 1195-1200 Chemical denotes probe http://purl.obolibrary.org/obo/CHEBI_50406
T375 1348-1355 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T376 1422-1425 Chemical denotes IAA http://purl.obolibrary.org/obo/CHEBI_16411
T377 1574-1577 Chemical denotes IAA http://purl.obolibrary.org/obo/CHEBI_16411
T378 1626-1629 Chemical denotes DTT http://purl.obolibrary.org/obo/CHEBI_18320
T379 1735-1738 Chemical denotes ABC http://purl.obolibrary.org/obo/CHEBI_421707
T380 1761-1765 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T381 1788-1795 Chemical denotes Trypsin http://purl.obolibrary.org/obo/CHEBI_9765
T382 1925-1945 Chemical denotes trifluoroacetic acid http://purl.obolibrary.org/obo/CHEBI_45892
T383 1941-1945 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T384 1947-1950 Chemical denotes TFA http://purl.obolibrary.org/obo/CHEBI_45892
T385 2113-2125 Chemical denotes acetonitrile http://purl.obolibrary.org/obo/CHEBI_38472
T386 2127-2130 Chemical denotes ACN http://purl.obolibrary.org/obo/CHEBI_38472
T387 2137-2140 Chemical denotes TFA http://purl.obolibrary.org/obo/CHEBI_45892
T388 2182-2185 Chemical denotes TFA http://purl.obolibrary.org/obo/CHEBI_45892
T389 2258-2261 Chemical denotes TFA http://purl.obolibrary.org/obo/CHEBI_45892
T390 2307-2310 Chemical denotes ACN http://purl.obolibrary.org/obo/CHEBI_38472
T391 2317-2328 Chemical denotes formic acid http://purl.obolibrary.org/obo/CHEBI_30751
T392 2324-2328 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T393 2330-2332 Chemical denotes FA http://purl.obolibrary.org/obo/CHEBI_39002|http://purl.obolibrary.org/obo/CHEBI_73630|http://purl.obolibrary.org/obo/CHEBI_30751
T396 2369-2376 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T397 2702-2706 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T399 2740-2743 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T400 2777-2782 Chemical denotes FeCl3 http://purl.obolibrary.org/obo/CHEBI_30808
T401 2815-2818 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T402 2856-2858 Chemical denotes FA http://purl.obolibrary.org/obo/CHEBI_39002|http://purl.obolibrary.org/obo/CHEBI_73630|http://purl.obolibrary.org/obo/CHEBI_30751
T405 2878-2880 Chemical denotes Fe http://purl.obolibrary.org/obo/CHEBI_18248
T406 2918-2921 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T407 3016-3019 Chemical denotes ACN http://purl.obolibrary.org/obo/CHEBI_38472
T408 3026-3029 Chemical denotes TFA http://purl.obolibrary.org/obo/CHEBI_45892
T409 3048-3056 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T410 3081-3084 Chemical denotes ACN http://purl.obolibrary.org/obo/CHEBI_38472
T411 3091-3094 Chemical denotes TFA http://purl.obolibrary.org/obo/CHEBI_45892
T412 3227-3230 Chemical denotes ACN http://purl.obolibrary.org/obo/CHEBI_38472
T413 3237-3240 Chemical denotes TFA http://purl.obolibrary.org/obo/CHEBI_45892
T414 3275-3277 Chemical denotes FA http://purl.obolibrary.org/obo/CHEBI_39002|http://purl.obolibrary.org/obo/CHEBI_73630|http://purl.obolibrary.org/obo/CHEBI_30751
T417 3312-3321 Chemical denotes potassium http://purl.obolibrary.org/obo/CHEBI_26216
T418 3322-3331 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T422 3332-3338 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T423 3379-3381 Chemical denotes FA http://purl.obolibrary.org/obo/CHEBI_39002|http://purl.obolibrary.org/obo/CHEBI_73630|http://purl.obolibrary.org/obo/CHEBI_30751
T426 3493-3496 Chemical denotes ACN http://purl.obolibrary.org/obo/CHEBI_38472
T427 3503-3505 Chemical denotes FA http://purl.obolibrary.org/obo/CHEBI_39002|http://purl.obolibrary.org/obo/CHEBI_73630|http://purl.obolibrary.org/obo/CHEBI_30751
T430 3788-3792 Chemical denotes Flex http://purl.obolibrary.org/obo/CHEBI_138164
T431 3979-3981 Chemical denotes FA http://purl.obolibrary.org/obo/CHEBI_39002|http://purl.obolibrary.org/obo/CHEBI_73630|http://purl.obolibrary.org/obo/CHEBI_30751
T434 4020-4022 Chemical denotes FA http://purl.obolibrary.org/obo/CHEBI_39002|http://purl.obolibrary.org/obo/CHEBI_73630|http://purl.obolibrary.org/obo/CHEBI_30751
T437 4027-4030 Chemical denotes ACN http://purl.obolibrary.org/obo/CHEBI_38472
T438 4454-4457 Chemical denotes DDA http://purl.obolibrary.org/obo/CHEBI_28139|http://purl.obolibrary.org/obo/CHEBI_91207
T440 4621-4623 Chemical denotes RF http://purl.obolibrary.org/obo/CHEBI_73818
T441 4659-4662 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T442 4818-4820 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T443 4821-4823 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T444 4898-4900 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T445 4901-4903 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T446 4958-4960 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T447 4961-4963 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T448 5149-5152 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T449 5253-5260 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T450 5280-5282 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T451 5283-5285 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T452 5332-5335 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T453 5417-5419 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T454 5522-5524 Chemical denotes RF http://purl.obolibrary.org/obo/CHEBI_73818
T455 5847-5850 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T456 5876-5883 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T457 5965-5968 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T458 6084-6087 Chemical denotes DDA http://purl.obolibrary.org/obo/CHEBI_28139|http://purl.obolibrary.org/obo/CHEBI_91207
T460 6334-6342 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T461 6388-6395 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T462 6629-6636 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T463 6732-6742 Chemical denotes methionine http://purl.obolibrary.org/obo/CHEBI_16811|http://purl.obolibrary.org/obo/CHEBI_64558
T465 6793-6801 Chemical denotes cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T466 6865-6872 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T467 6874-6881 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T468 6908-6915 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T469 7148-7155 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T470 7798-7810 Chemical denotes Triton X-100 http://purl.obolibrary.org/obo/CHEBI_9750
T471 7995-8002 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T472 8065-8072 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T473 8351-8361 Chemical denotes Phalloidin http://purl.obolibrary.org/obo/CHEBI_8040
T474 8527-8529 Chemical denotes NA http://purl.obolibrary.org/obo/CHEBI_33696
T475 8889-8891 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T476 8898-8905 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T477 9010-9017 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T478 9338-9345 Chemical denotes silicon http://purl.obolibrary.org/obo/CHEBI_27573
T479 9365-9373 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T480 9415-9423 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T481 9449-9457 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T482 9550-9564 Chemical denotes glutaraldehyde http://purl.obolibrary.org/obo/CHEBI_64276
T483 9585-9594 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T487 9595-9601 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T488 9633-9649 Chemical denotes osmium tetroxide http://purl.obolibrary.org/obo/CHEBI_88215
T489 9633-9639 Chemical denotes osmium http://purl.obolibrary.org/obo/CHEBI_30687
T490 9655-9677 Chemical denotes potassium ferrocyanide http://purl.obolibrary.org/obo/CHEBI_30059
T491 9655-9664 Chemical denotes potassium http://purl.obolibrary.org/obo/CHEBI_26216
T492 9665-9677 Chemical denotes ferrocyanide http://purl.obolibrary.org/obo/CHEBI_5032
T493 9687-9704 Chemical denotes sodium cacodylate http://purl.obolibrary.org/obo/CHEBI_62956
T494 9687-9693 Chemical denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708
T495 9705-9711 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T496 9730-9747 Chemical denotes sodium cacodylate http://purl.obolibrary.org/obo/CHEBI_62956
T497 9730-9736 Chemical denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708
T498 9748-9754 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T499 9776-9787 Chemical denotes tannic acid http://purl.obolibrary.org/obo/CHEBI_75211
T500 9783-9787 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T501 9814-9820 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T502 9872-9888 Chemical denotes osmium tetroxide http://purl.obolibrary.org/obo/CHEBI_88215
T503 9872-9878 Chemical denotes osmium http://purl.obolibrary.org/obo/CHEBI_30687
T504 9897-9914 Chemical denotes sodium cacodylate http://purl.obolibrary.org/obo/CHEBI_62956
T505 9897-9903 Chemical denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708
T506 9979-9986 Chemical denotes ethanol http://purl.obolibrary.org/obo/CHEBI_16236
T507 10065-10068 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T508 10154-10160 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T510 10169-10177 Chemical denotes aluminum http://purl.obolibrary.org/obo/CHEBI_28984
T511 10239-10246 Chemical denotes iridium http://purl.obolibrary.org/obo/CHEBI_49666
T512 10325-10327 Chemical denotes PA http://purl.obolibrary.org/obo/CHEBI_30745|http://purl.obolibrary.org/obo/CHEBI_30768|http://purl.obolibrary.org/obo/CHEBI_74753|http://purl.obolibrary.org/obo/CHEBI_7959|http://purl.obolibrary.org/obo/CHEBI_8429
T517 10399-10407 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T518 10461-10469 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T519 10482-10485 Chemical denotes TEM http://purl.obolibrary.org/obo/CHEBI_27919
T520 10541-10549 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T521 10611-10618 Chemical denotes acetate http://purl.obolibrary.org/obo/CHEBI_30089|http://purl.obolibrary.org/obo/CHEBI_47622
T523 10643-10649 Chemical denotes osmium http://purl.obolibrary.org/obo/CHEBI_30687
T524 10700-10707 Chemical denotes ethanol http://purl.obolibrary.org/obo/CHEBI_16236
T525 10818-10820 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T527 10858-10860 Chemical denotes BT http://purl.obolibrary.org/obo/CHEBI_45993
T528 10881-10889 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T529 11055-11062 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T530 11676-11679 Chemical denotes PEG http://purl.obolibrary.org/obo/CHEBI_46793
T531 11694-11709 Chemical denotes sodium chloride http://purl.obolibrary.org/obo/CHEBI_26710
T532 11694-11700 Chemical denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708
T533 11701-11709 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T534 11711-11715 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T535 12116-12125 Chemical denotes Puromycin http://purl.obolibrary.org/obo/CHEBI_17939
T536 12274-12285 Chemical denotes doxycycline http://purl.obolibrary.org/obo/CHEBI_50845|http://purl.obolibrary.org/obo/CHEBI_60648
T538 12411-12415 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T539 12424-12432 Chemical denotes ammonium http://purl.obolibrary.org/obo/CHEBI_28938
T540 12446-12449 Chemical denotes ABC http://purl.obolibrary.org/obo/CHEBI_421707
T541 12459-12463 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T542 12465-12483 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T544 12474-12483 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T545 12523-12533 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T546 12557-12564 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T547 13118-13120 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T548 13389-13396 Chemical denotes Trypsin http://purl.obolibrary.org/obo/CHEBI_9765
T549 13488-13496 Chemical denotes Formalin http://purl.obolibrary.org/obo/CHEBI_16842
T550 13594-13606 Chemical denotes Triton X-100 http://purl.obolibrary.org/obo/CHEBI_9750
T551 13711-13723 Chemical denotes phenylindole http://purl.obolibrary.org/obo/CHEBI_48559
T552 13725-13729 Chemical denotes DAPI http://purl.obolibrary.org/obo/CHEBI_51231
T553 14330-14334 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T554 14338-14346 Chemical denotes SB203580 http://purl.obolibrary.org/obo/CHEBI_90705
T555 14515-14524 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T556 14909-14916 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T557 14977-14983 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T558 15000-15003 Chemical denotes SDS http://purl.obolibrary.org/obo/CHEBI_8984
T559 15261-15263 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T560 15482-15484 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T561 15741-15745 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T562 16044-16047 Chemical denotes MCP http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099
T564 16090-16094 Chemical denotes CCL7 http://purl.obolibrary.org/obo/CHEBI_138183
T565 16095-16098 Chemical denotes MCP http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099
T567 16107-16110 Chemical denotes MCP http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099
T569 16135-16138 Chemical denotes MCP http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099
T571 16148-16153 Chemical denotes MIP-3 http://purl.obolibrary.org/obo/CHEBI_138161
T572 16180-16185 Chemical denotes CXCL5 http://purl.obolibrary.org/obo/CHEBI_138180
T573 16200-16202 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T575 16206-16211 Chemical denotes CXCL9 http://purl.obolibrary.org/obo/CHEBI_138154
T576 16217-16223 Chemical denotes CXCL10 http://purl.obolibrary.org/obo/CHEBI_138157
T577 16224-16229 Chemical denotes IP-10 http://purl.obolibrary.org/obo/CHEBI_138157
T578 16224-16226 Chemical denotes IP http://purl.obolibrary.org/obo/CHEBI_74076
T579 16239-16241 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T581 16246-16248 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T583 16253-16255 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T585 16261-16263 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T587 16267-16269 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T589 16273-16275 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T591 16279-16281 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T593 16286-16288 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T595 16296-16298 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T597 16303-16305 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T599 16310-16312 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T601 16318-16320 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T603 16325-16327 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T604 16333-16336 Chemical denotes MMP http://purl.obolibrary.org/obo/CHEBI_340824|http://purl.obolibrary.org/obo/CHEBI_59761
T606 16484-16486 Chemical denotes MN http://purl.obolibrary.org/obo/CHEBI_141442
T607 17056-17066 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T608 17368-17372 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T609 17693-17705 Chemical denotes formaldehyde http://purl.obolibrary.org/obo/CHEBI_16842
T610 17815-17817 Chemical denotes NP http://purl.obolibrary.org/obo/CHEBI_50803|http://purl.obolibrary.org/obo/CHEBI_53793|http://purl.obolibrary.org/obo/CHEBI_73425
T613 17818-17825 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T614 17889-17893 Chemical denotes DAPI http://purl.obolibrary.org/obo/CHEBI_51231
T615 17949-17953 Chemical denotes DAPI http://purl.obolibrary.org/obo/CHEBI_51231
T616 18073-18075 Chemical denotes NP http://purl.obolibrary.org/obo/CHEBI_50803|http://purl.obolibrary.org/obo/CHEBI_53793|http://purl.obolibrary.org/obo/CHEBI_73425
T619 18076-18083 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T620 18091-18098 Chemical denotes nucleus http://purl.obolibrary.org/obo/CHEBI_33252
T621 18242-18246 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T622 18392-18402 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T623 18989-19003 Chemical denotes crystal violet http://purl.obolibrary.org/obo/CHEBI_41688
T624 19170-19173 Chemical denotes MTT http://purl.obolibrary.org/obo/CHEBI_53233
T64554 20439-20449 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T5336 21558-21565 Chemical denotes Agarose http://purl.obolibrary.org/obo/CHEBI_2511
T98246 21707-21715 Chemical denotes Formalin http://purl.obolibrary.org/obo/CHEBI_16842
T9421 21781-21789 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T80120 22197-22204 Chemical denotes ethanol http://purl.obolibrary.org/obo/CHEBI_16236

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T450 441-446 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T451 454-459 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T452 464-473 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T453 615-620 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T454 933-938 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T455 1051-1062 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T456 1910-1919 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T457 7020-7035 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T458 7398-7410 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T459 11868-11875 http://purl.obolibrary.org/obo/GO_0051235 denotes storage
T460 12093-12105 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T461 12511-12522 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T462 12557-12574 http://purl.obolibrary.org/obo/GO_0044256 denotes protein digestion
T463 12565-12574 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T464 12990-13005 http://purl.obolibrary.org/obo/GO_0016301 denotes Kinase activity
T465 13054-13069 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T466 13124-13134 http://purl.obolibrary.org/obo/GO_0007049 denotes Cell cycle
T467 13778-13788 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T468 14235-14240 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T469 14963-14968 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T470 15054-15069 http://purl.obolibrary.org/obo/GO_0010467 denotes Gene expression
T471 15153-15174 http://purl.obolibrary.org/obo/GO_0001171 denotes Reverse transcription
T472 15161-15174 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T473 15272-15285 http://purl.obolibrary.org/obo/GO_0003968 denotes Transcriptase
T474 15272-15285 http://purl.obolibrary.org/obo/GO_0003899 denotes Transcriptase
T475 15414-15418 http://purl.obolibrary.org/obo/GO_0033867 denotes FAST
T476 15767-15784 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T477 15767-15784 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T478 16253-16259 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1RA
T479 19339-19356 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T480 19339-19356 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id tao:has_standard_notation
1768 30-39 Disease denotes infection MESH:D007239
1769 22-24 CellLine denotes E6 CVCL:4582
1776 189-199 Species denotes SARS-CoV-2 Tax:2697049
1777 228-232 Chemical denotes DMEM
1778 374-378 Chemical denotes DMEM
1779 163-171 Disease denotes infected MESH:D007239
1780 175-183 Disease denotes infected MESH:D007239
1781 68-70 CellLine denotes E6 CVCL:4582
1810 1785-1786 Gene denotes M Gene:43740571
1811 1733-1734 Gene denotes M Gene:43740571
1812 949-950 Gene denotes M Gene:43740571
1813 1988-1990 Gene denotes pH Gene:5053
1814 1740-1742 Gene denotes pH Gene:5053
1815 2040-2043 Gene denotes Pak
1816 518-521 Chemical denotes PBS MESH:D007854
1817 779-787 Chemical denotes methanol MESH:D000432
1818 951-955 Chemical denotes urea MESH:D014508
1819 964-984 Chemical denotes ammonium bicarbonate MESH:C027043
1820 999-1003 Chemical denotes NaCl MESH:D012965
1821 1093-1123 Chemical denotes Tris-(2-carboxyethyl)phosphine MESH:C080938
1822 1125-1129 Chemical denotes TCEP MESH:C080938
1823 1407-1420 Chemical denotes Iodoacetamide MESH:D007460
1824 1422-1425 Chemical denotes IAA MESH:D007460
1825 1574-1577 Chemical denotes IAA MESH:D007460
1826 1610-1624 Chemical denotes dithiothreitol MESH:D004229
1827 1626-1629 Chemical denotes DTT MESH:D004229
1828 1761-1765 Chemical denotes urea MESH:D014508
1829 1925-1945 Chemical denotes trifluoroacetic acid MESH:D014269
1830 1947-1950 Chemical denotes TFA MESH:D014269
1831 2113-2125 Chemical denotes acetonitrile MESH:C032159
1832 2127-2130 Chemical denotes ACN MESH:C032159
1833 2137-2140 Chemical denotes TFA MESH:D014269
1834 2182-2185 Chemical denotes TFA MESH:D014269
1835 2258-2261 Chemical denotes TFA MESH:D014269
1836 2307-2310 Chemical denotes ACN MESH:C032159
1837 2317-2328 Chemical denotes formic acid MESH:C030544
1839 2505-2519 Chemical denotes Phosphopeptide MESH:D010748
1855 3339-3341 Gene denotes pH Gene:5053
1856 2702-2706 Chemical denotes EDTA MESH:D004492
1857 2740-2743 Chemical denotes H2O
1858 2777-2782 Chemical denotes FeCl3
1859 2815-2818 Chemical denotes H2O
1860 2878-2880 Chemical denotes Fe MESH:D007501
1861 2918-2921 Chemical denotes H2O
1862 3016-3019 Chemical denotes ACN MESH:C032159
1863 3026-3029 Chemical denotes TFA MESH:D014269
1864 3081-3084 Chemical denotes ACN MESH:C032159
1865 3091-3094 Chemical denotes TFA MESH:D014269
1866 3227-3230 Chemical denotes ACN MESH:C032159
1867 3237-3240 Chemical denotes TFA MESH:D014269
1868 3312-3331 Chemical denotes potassium phosphate MESH:C013216
1869 3493-3496 Chemical denotes ACN MESH:C032159
1874 4027-4030 Chemical denotes ACN MESH:C032159
1875 4925-4939 Chemical denotes phosphopeptide MESH:D010748
1876 5746-5760 Chemical denotes phosphopeptide MESH:D010748
1877 3915-3926 Disease denotes ReprosilPur
1892 6567-6572 Gene denotes ORF3a Gene:43740569
1893 7039-7040 Gene denotes S Gene:43740568
1894 6543-6548 Gene denotes Spike Gene:43740568
1895 6377-6387 Species denotes SARS-CoV-2 Tax:2697049
1896 6617-6623 Species denotes stocks Tax:3724
1897 6304-6315 Species denotes Chlorocebus Tax:60711
1898 6732-6742 Chemical denotes methionine MESH:D008715
1899 6777-6801 Chemical denotes carbamidomethyl cysteine MESH:C034636
1900 6949-6963 Chemical denotes phosphopeptide MESH:D010748
1901 7249-7263 Chemical denotes phosphopeptide MESH:D010748
1902 6535-6542 Mutation denotes G22661T g.22661G>T
1903 6549-6554 Mutation denotes V367F p.V367F
1904 6559-6566 Mutation denotes G26144T g.26144G>T
1905 6573-6578 Mutation denotes G251V p.G251V
1929 7558-7563 Gene denotes IMB-1 Gene:3837
1930 7943-7947 Gene denotes CK2α Gene:1459
1931 8896-8897 Gene denotes N Gene:43740575
1932 7535-7545 Species denotes SARS-CoV-2 Tax:2697049
1933 7973-7981 Species denotes SARS-CoV Tax:694009
1934 8039-8047 Species denotes SARS-CoV Tax:694009
1935 8269-8274 Species denotes mouse Tax:10090
1936 7693-7696 Chemical denotes PBS MESH:D007854
1937 7713-7729 Chemical denotes paraformaldehyde MESH:C003043
1938 7733-7736 Chemical denotes PBS MESH:D007854
1939 7798-7810 Chemical denotes Triton X-100 MESH:D017830
1940 7814-7817 Chemical denotes PBS MESH:D007854
1941 7878-7881 Chemical denotes PBS MESH:D007854
1942 8157-8160 Chemical denotes PBS MESH:D007854
1943 8188-8193 Chemical denotes AF568
1944 8337-8342 Chemical denotes AF488
1945 8351-8361 Chemical denotes Phalloidin MESH:D010590
1946 7521-7529 Disease denotes infected MESH:D007239
1947 7660-7669 Disease denotes infection MESH:D007239
1948 8944-8963 Disease denotes SARS-CoV-2 infected MESH:C000657245
1949 7476-7482 CellLine denotes Caco-2 CVCL:0025
1950 7593-7595 CellLine denotes E6 CVCL:4582
1951 8964-8970 CellLine denotes Caco-2 CVCL:0025
1975 9728-9729 Gene denotes M Gene:43740571
1976 9685-9686 Gene denotes M Gene:43740571
1977 9572-9573 Gene denotes M Gene:43740571
1978 9302-9312 Species denotes SARS-CoV-2 Tax:2697049
1979 9321-9325 Species denotes nCoV Tax:2697049
1980 9338-9345 Chemical denotes silicon MESH:D012825
1981 9528-9544 Chemical denotes paraformaldehyde MESH:C003043
1982 9550-9564 Chemical denotes glutaraldehyde MESH:D005976
1983 9574-9594 Chemical denotes Sorenson’s phosphate
1984 9633-9649 Chemical denotes osmium tetroxide MESH:D009993
1985 9655-9677 Chemical denotes potassium ferrocyanide MESH:C031835
1986 9687-9704 Chemical denotes sodium cacodylate
1987 9730-9747 Chemical denotes sodium cacodylate
1988 9776-9787 Chemical denotes tannic acid MESH:D013634
1989 9791-9795 Chemical denotes dH2O
1990 9872-9888 Chemical denotes osmium tetroxide MESH:D009993
1991 9897-9914 Chemical denotes sodium cacodylate
1992 9933-9937 Chemical denotes dH2O
1993 10604-10618 Chemical denotes uranyl acetate MESH:C005460
1994 10643-10649 Chemical denotes osmium MESH:D009992
1995 10700-10707 Chemical denotes ethanol MESH:D000431
1996 9275-9283 Disease denotes infected MESH:D007239
1997 9235-9237 CellLine denotes E6 CVCL:4582
2000 11015-11016 Gene denotes N Gene:43740575
2001 11040-11042 CellLine denotes E6 CVCL:4582
2029 11096-11100 Gene denotes EF1a Gene:1917
2030 12409-12410 Gene denotes M Gene:43740571
2031 12035-12036 Gene denotes N Gene:43740575
2032 11269-11270 Gene denotes N Gene:43740575
2033 11112-11113 Gene denotes N Gene:43740575
2034 11053-11054 Gene denotes N Gene:43740575
2035 11101-11111 Species denotes SARS-CoV-2 Tax:2697049
2036 11258-11268 Species denotes SARS-CoV-2 Tax:2697049
2037 12024-12034 Species denotes SARS-CoV-2 Tax:2697049
2038 12642-12652 Species denotes SARS-CoV-2 Tax:2697049
2039 11545-11548 Species denotes VSV Tax:11276
2040 11164-11170 Chemical denotes TetOne
2041 11246-11252 Chemical denotes TetOne
2042 11676-11684 Chemical denotes PEG-6000 MESH:C000595215
2043 11694-11709 Chemical denotes sodium chloride MESH:D012965
2044 11711-11715 Chemical denotes NaCl MESH:D012965
2045 12012-12018 Chemical denotes TetOne
2046 12053-12059 Chemical denotes TetOne
2047 12116-12125 Chemical denotes Puromycin MESH:D011691
2048 12274-12285 Chemical denotes doxycycline MESH:D004318
2049 12411-12415 Chemical denotes urea MESH:D014508
2050 12424-12444 Chemical denotes ammonium bicarbonate MESH:C027043
2051 12459-12463 Chemical denotes NaCl MESH:D012965
2052 12325-12333 Disease denotes cold PBS MESH:D011535
2053 12363-12371 Disease denotes cold PBS MESH:D011535
2054 11370-11377 CellLine denotes HEK293T CVCL:0063
2055 11890-11892 CellLine denotes E6 CVCL:4582
2069 14169-14170 Gene denotes S Gene:43740568
2070 14179-14180 Gene denotes M Gene:43740571
2071 13255-13265 Species denotes SARS-CoV-2 Tax:2697049
2072 13275-13282 Species denotes BetaCoV Tax:694002
2073 13488-13496 Chemical denotes Formalin MESH:D005557
2074 13548-13551 Chemical denotes PBS MESH:D007854
2075 13594-13606 Chemical denotes Triton X-100 MESH:D017830
2076 13694-13723 Chemical denotes 4′,6-diamidino-2-phenylindole MESH:C007293
2077 13725-13729 Chemical denotes DAPI MESH:C007293
2078 13742-13745 Chemical denotes PBS MESH:D007854
2079 13229-13237 Disease denotes infected MESH:D007239
2080 13241-13249 Disease denotes infected MESH:D007239
2081 13155-13157 CellLine denotes E6 CVCL:4582
2085 14215-14219 Gene denotes ACE2 Gene:59272
2086 14190-14211 Disease denotes SARS-CoV-2 infections MESH:C000657245
2087 14220-14224 CellLine denotes A549 CVCL:0023
2098 14446-14456 Species denotes SARS-CoV-2 Tax:2697049
2099 14330-14334 Chemical denotes DMSO MESH:D004121
2100 14338-14346 Chemical denotes SB203580 MESH:C093642
2101 14747-14753 Chemical denotes TRIzol MESH:C411644
2102 14972-14983 Chemical denotes RIPA buffer
2103 15000-15003 Chemical denotes SDS MESH:D012967
2104 14432-14440 Disease denotes infected MESH:D007239
2105 14571-14580 Disease denotes infection MESH:D007239
2106 14604-14612 Disease denotes infected MESH:D007239
2107 14285-14294 CellLine denotes A549-ACE2 CVCL:0023
2114 15632-15636 Gene denotes ACTB Gene:60
2115 15572-15573 Gene denotes N Gene:43740575
2116 15103-15113 Species denotes SARS-CoV-2 Tax:2697049
2117 15741-15745 Chemical denotes DMSO MESH:D004121
2118 15692-15700 Disease denotes infected MESH:D007239
2119 15732-15740 Disease denotes infected MESH:D007239
2165 16039-16043 Gene denotes CCL2 Gene:6347
2166 16064-16068 Gene denotes CCL4 Gene:6351
2167 16069-16075 Gene denotes MIP-1β Gene:6351
2168 16077-16081 Gene denotes CCL5 Gene:6352
2169 16082-16088 Gene denotes RANTES Gene:6352
2170 16090-16094 Gene denotes CCL7 Gene:6354
2171 16102-16106 Gene denotes CCL8 Gene:6355
2172 16114-16119 Gene denotes CCL11 Gene:6356
2173 16120-16127 Gene denotes Eotaxin Gene:6356
2174 16129-16134 Gene denotes CCL13 Gene:6357
2175 16142-16147 Gene denotes CCL20 Gene:6364
2176 16148-16154 Gene denotes MIP-3α Gene:6364
2177 16156-16161 Gene denotes CXCL1 Gene:2919
2178 16162-16166 Gene denotes GROα Gene:2919
2179 16168-16173 Gene denotes CXCL2 Gene:2920
2180 16174-16178 Gene denotes GROβ Gene:2919
2181 16180-16185 Gene denotes CXCL5 Gene:6374
2182 16186-16192 Gene denotes ENA-78 Gene:6374
2183 16194-16199 Gene denotes CXCL8 Gene:3576
2184 16200-16204 Gene denotes IL-8 Gene:3576
2185 16206-16211 Gene denotes CXCL9 Gene:4283
2186 16212-16215 Gene denotes MIG Gene:4283
2187 16217-16223 Gene denotes CXCL10 Gene:3627
2188 16224-16229 Gene denotes IP-10 Gene:3627
2189 16231-16237 Gene denotes CXCL16 Gene:58191
2190 16239-16244 Gene denotes IL-1α Gene:3552
2191 16246-16251 Gene denotes IL-1β Gene:3552
2192 16253-16259 Gene denotes IL-1RA Gene:3557
2193 16261-16265 Gene denotes IL-4 Gene:3565
2194 16267-16271 Gene denotes IL-6 Gene:3569
2195 16273-16277 Gene denotes IL-7 Gene:3574
2196 16279-16284 Gene denotes IL-10 Gene:3586
2197 16296-16301 Gene denotes IL-15 Gene:3600
2198 16303-16308 Gene denotes IL-16 Gene:3603
2199 16310-16316 Gene denotes IL-17A Gene:3605
2200 16318-16323 Gene denotes IL-22 Gene:50616
2201 16325-16331 Gene denotes GM-CSF Gene:1437
2202 16333-16338 Gene denotes MMP-9 Gene:4318
2203 16340-16346 Gene denotes S100A8 Gene:6279
2204 16348-16352 Gene denotes TNFα Gene:7124
2205 16354-16358 Gene denotes TGFβ Gene:7039
2206 16364-16373 Gene denotes Trappin-2 Gene:5266
2207 16374-16380 Gene denotes Elafin Gene:5266
2208 15934-15942 Disease denotes infected MESH:D007239
2209 16484-16486 CellLine denotes MN CVCL:U508
2211 16987-16997 Species denotes SARS-CoV-2 Tax:2697049
2237 17450-17460 Species denotes SARS-CoV-2 Tax:2697049
2238 18814-18824 Species denotes SARS-CoV-2 Tax:2697049
2239 18443-18453 Species denotes infectious Tax:11120
2240 18498-18508 Species denotes Infectious Tax:11120
2241 18539-18549 Species denotes infectious Tax:11120
2242 18642-18652 Species denotes Infectious Tax:11120
2243 17254-17258 Chemical denotes DMEM
2244 17368-17372 Chemical denotes DMSO MESH:D004121
2245 17495-17499 Chemical denotes DMEM
2246 17693-17705 Chemical denotes formaldehyde MESH:D005557
2247 17889-17893 Chemical denotes DAPI MESH:C007293
2248 18242-18246 Chemical denotes DMSO MESH:D004121
2249 18989-19003 Chemical denotes crystal violet MESH:D005840
2250 17204-17213 Disease denotes infection MESH:D007239
2251 17627-17636 Disease denotes infection MESH:D007239
2252 17908-17916 Disease denotes Infected MESH:D007239
2253 18157-18166 Disease denotes infection MESH:D007239
2254 18187-18195 Disease denotes Infected MESH:D007239
2255 18276-18285 Disease denotes infection MESH:D007239
2256 18404-18412 Disease denotes infected MESH:D007239
2257 18595-18604 Disease denotes infection MESH:D007239
2258 17118-17120 CellLine denotes E6 CVCL:4582
2259 18111-18113 CellLine denotes E6 CVCL:4582
2260 18715-18717 CellLine denotes E6 CVCL:4582
2261 18739-18741 CellLine denotes E6 CVCL:4582
2263 19068-19080 Disease denotes Cytotoxicity MESH:D064420
2268 19170-19173 Chemical denotes MTT MESH:C070243
2269 19128-19140 Disease denotes Cytotoxicity MESH:D064420
2270 19235-19247 Disease denotes Cytotoxicity MESH:D064420
2271 19281-19283 CellLine denotes E6 CVCL:4582
2277 19560-19564 Gene denotes ACE2 Gene:59272
2278 20140-20154 Chemical denotes Opti-MEM media
2279 20235-20244 Disease denotes infection MESH:D007239
2280 19531-19535 CellLine denotes A549 CVCL:0023
2281 19637-19646 CellLine denotes A549-ACE2 CVCL:0023
2283 20380-20390 Species denotes SARS-CoV-2 Tax:2697049
2286 20636-20637 Gene denotes N Gene:43740575
2287 20594-20604 Species denotes SARS-CoV-2 Tax:2697049
2289 21182-21192 Species denotes SARS-CoV-2 Tax:2697049
2295 21397-21406 Chemical denotes MEM media
2296 21558-21565 Chemical denotes Agarose MESH:D012685
2297 21707-21715 Chemical denotes Formalin MESH:D005557
2298 21766-21780 Chemical denotes crystal Violet MESH:D005840
2299 21251-21253 CellLine denotes E6 CVCL:4582
2301 22197-22204 Chemical denotes ethanol MESH:D000431

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T719 0-15 Sentence denotes Methods Details
T720 17-62 Sentence denotes Vero E6 cell infection for proteomic analysis
T721 63-121 Sentence denotes Vero E6 cells were seeded using 2x106 cells in T25 flasks.
T722 122-252 Sentence denotes The following day cells were either mock infected or infected with SARS-CoV-2 at a MOI of 1 in serum-free DMEM at 37°C for 1 hour.
T723 253-447 Sentence denotes After absorption the 0 hour samples were lysed immediately, while the media for other samples was replaced with 2% FBS / DMEM (Invitrogen) and incubated at 37°C for times indicated before lysis.
T724 449-473 Sentence denotes Cell lysis and digestion
T725 474-599 Sentence denotes Cells were lysed using 1% IGEPAL (Sigma) in PBS (Invitrogen) for 20 minutes at room temperature (RT) to inactivate the virus.
T726 600-695 Sentence denotes These specific lysis conditions were used as this was the approved virus inactivation protocol.
T727 696-848 Sentence denotes Proteins contained in the cell lysate were then immediately precipitated using 90% methanol (v/v) (Sigma) by centrifugation at 20,000x g for 10 minutes.
T728 849-890 Sentence denotes The protein pellets were frozen at −80°C.
T729 891-1092 Sentence denotes Precipitated proteins were resuspended in lysis buffer (8 M urea, 100 mM ammonium bicarbonate (ABC), 150 mM NaCl, protease inhibitor (mini-cOmplete, Roche) and phosphatase inhibitors (phosSTOP, Roche).
T730 1093-1174 Sentence denotes Tris-(2-carboxyethyl)phosphine (TCEP) was added to a final concentration of 4 mM.
T731 1175-1274 Sentence denotes DNA was sheared via probe sonication, on ice, at 20% amplitude for 20 s., followed by 10 s of rest.
T732 1275-1325 Sentence denotes This process was performed a total of three times.
T733 1326-1406 Sentence denotes Following sonication, protein concentration was determined using Bradford assay.
T734 1407-1566 Sentence denotes Iodoacetamide (IAA) was added to each sample to a final concentration of 10 mM, and samples were incubated in the dark at room temperature (RT) for 30 minutes.
T735 1567-1697 Sentence denotes Excess IAA was quenched by the addition of dithiothreitol (DTT) to 10 mM, followed by incubation in the dark at RT for 30 minutes.
T736 1698-1787 Sentence denotes Samples were then diluted with 0.1 M ABC (pH = 8.0) to a final urea concentration of 2 M.
T737 1788-1899 Sentence denotes Trypsin (Promega) was added at a 1:100 (enzyme:protein w:w) ratio and digested overnight at 37°C with rotation.
T738 1900-1994 Sentence denotes Following digestion, 10% trifluoroacetic acid (TFA) was added to each sample to a final pH ∼2.
T739 1995-2069 Sentence denotes Samples were desalted under vacuum using Sep Pak tC18 cartridges (Waters).
T740 2070-2186 Sentence denotes Each cartridge was activated with 1 mL 80% acetonitrile (ACN)/0.1% TFA, then equilibrated with 3 × 1 mL of 0.1% TFA.
T741 2187-2334 Sentence denotes Following sample loading, cartridges were washed with 4 × 1 mL of 0.1% TFA, and samples were eluted with 4 × 0.5 mL 50% ACN/0.25% formic acid (FA).
T742 2335-2458 Sentence denotes 20 μg of each sample was kept for protein abundance measurements, and the remainder was used for phosphopeptide enrichment.
T743 2459-2503 Sentence denotes Samples were dried by vacuum centrifugation.
T744 2505-2530 Sentence denotes Phosphopeptide enrichment
T745 2531-2654 Sentence denotes For each sample batch, 400 μL (30 μL per sample) of 50% Superflow bead slurry (QIAGEN) was added to a 2 mL bio-spin column.
T746 2655-2881 Sentence denotes Beads were incubated with 4 × 500 μL of 100 mM EDTA for 30 s, washed with 2 × 500 μL H2O, incubated 4 × 500 μL with 15 mM FeCl3 for 1 minute, washed 3 × 500 μL H2O, and washed once with 500 μL of 0.5% FA to remove residual Fe.
T747 2882-3030 Sentence denotes Beads were resuspended in 600 μL of H2O and 60 μL were aliquoted into a C18 NEST column that had been equilibrated with 150 μL of 80% ACN, 0.1% TFA.
T748 3031-3188 Sentence denotes 1 mg of digested peptides were resuspended in 75% ACN/0.15% TFA and incubated with beads for 2 minutes, mixed by pipetting and incubated again for 2 minutes.
T749 3189-3397 Sentence denotes Beads were washed 4 × 200 μL with 80% ACN, 0.1% TFA, then washed 3 × 200 uL with 0.5% FA, incubated 2 × 200 μL with 500 mM potassium phosphate buffer pH 7 and incubated 2 × 200 μL with 0.5% FA for 15 seconds.
T750 3398-3506 Sentence denotes Phosphopeptides were eluted by centrifugation at 3000 RPM for 30 seconds with 2 × 75 uL of 50% ACN, 0.1% FA.
T751 3508-3542 Sentence denotes Mass spectrometry data acquisition
T752 3543-3817 Sentence denotes Digested samples were analyzed on an Orbitrap Exploris 480 mass spectrometry system (Thermo Fisher Scientific) equipped with an Easy nLC 1200 ultra-high pressure liquid chromatography system (Thermo Fisher Scientific) interfaced via a Nanospray Flex nanoelectrospray source.
T753 3818-3945 Sentence denotes For all analyses, samples were injected on a C18 reverse phase column (25 cm x 75 μm packed with ReprosilPur 1.9 μm particles).
T754 3946-4031 Sentence denotes Mobile phase A consisted of 0.1% FA, and mobile phase B consisted of 0.1% FA/80% ACN.
T755 4032-4242 Sentence denotes Peptides were separated by an organic gradient from 5% to 30% mobile phase B over 112 minutes followed by an increase to 58% B over 12 minutes, then held at 90% B for 16 minutes at a flow rate of 350 nL/minute.
T756 4243-4308 Sentence denotes Analytical columns were equilibrated with 6 μL of mobile phase A.
T757 4309-4428 Sentence denotes To build a spectral library, one sample from each set of biological replicates was acquired in a data dependent manner.
T758 4429-4687 Sentence denotes Data dependent analysis (DDA) was performed by acquiring a full scan over a m/z range of 400-1000 in the Orbitrap at 60,000 resolving power (@200 m/z) with a normalized AGC target of 300%, an RF lens setting of 40%, and a maximum ion injection time of 60 ms.
T759 4688-4767 Sentence denotes Dynamic exclusion was set to 60 seconds, with a 10 ppm exclusion width setting.
T760 4768-4920 Sentence denotes Peptides with charge states 2-6 were selected for MS/MS interrogation using higher energy collisional dissociation (HCD), with 20 MS/MS scans per cycle.
T761 4921-5168 Sentence denotes For phosphopeptide enriched samples, MS/MS scans were analyzed in the Orbitrap using isolation width of 1.3 m/z, normalized HCD collision energy of 30%, normalized AGC of 200% at a resolving power of 30,000 with a 54 ms maximum ion injection time.
T762 5169-5351 Sentence denotes Similar settings were used for data dependent analysis of samples used to determine protein abundance, with an MS/MS resolving power of 15,000 and a 22 ms maximum ion injection time.
T763 5352-5413 Sentence denotes Data-independent analysis (DIA) was performed on all samples.
T764 5414-5712 Sentence denotes An MS scan at 60,000 resolving power over a scan range of 390-1010 m/z, a normalized AGC target of 300%, an RF lens setting of 40%, and a maximum injection time of 60 ms was acquired, followed by DIA scans using 8 m/z isolation windows over 400-1000 m/z at a normalized HCD collision energy of 27%.
T765 5713-5741 Sentence denotes Loop control was set to All.
T766 5742-5875 Sentence denotes For phosphopeptide enriched samples, data were collected using a resolving power of 30,000 and a maximum ion injection time of 54 ms.
T767 5876-5993 Sentence denotes Protein abundance samples were collected using a resolving power of 15,000 and a maximum ion injection time of 22 ms.
T768 5995-6046 Sentence denotes Spectral library generation and raw data processing
T769 6047-6624 Sentence denotes Raw mass spectrometry data from each DDA dataset were used to build separate libraries for DIA searches using the Pulsar search engine integrated into Spectronaut version 13.12.200217.43655 (Bruderer et al., 2015) by searching against a database of Uniprot Chlorocebus sequences (19,136 proteins, downloaded April 3, 2020) and 29 SARS-CoV-2 protein sequences translated from genomic sequence downloaded from GISAID (accession EPI_ISL_406596, downloaded April 7, 2020) with two mutations (G22661T Spike V367F and G26144T ORF3a G251V) detected by RNASeq analysis of virus stocks.
T770 6625-6944 Sentence denotes For protein abundance samples, data were searched using the default BGS settings, variable modification of methionine oxidation, static modification of carbamidomethyl cysteine, and filtering to a final 1% false discovery rate (FDR) at the peptide, peptide spectrum match (PSM), and protein level (Elias and Gygi 2007).
T771 6945-7078 Sentence denotes For phosphopeptide enriched samples, BGS settings were modified to include phosphorylation of S, T, and Y as a variable modification.
T772 7079-7143 Sentence denotes The generated search libraries were used to search the DIA data.
T773 7144-7244 Sentence denotes For protein abundance samples, default BGS settings were used, with no data normalization performed.
T774 7245-7444 Sentence denotes For phosphopeptide enriched samples, the Significant PTM default settings were used, with no data normalization performed, and the DIA-specific PTM site localization score in Spectronaut was applied.
T775 7446-7475 Sentence denotes Immunofluorescence microscopy
T776 7476-7642 Sentence denotes Caco-2 cells seeded on glass coverslips were infected with SARS-CoV-2 Isolate Muc-IMB-1/2020, second passage on Vero E6 cells (2x106 PFU/mL) at an MOI of 0.1 or 0.01.
T777 7643-7899 Sentence denotes At 24 hours post-infection cells were washed with PBS and fixed in 4% paraformaldehyde in PBS for 20 minutes at RT, followed by permeabilization with 0.3% Triton X-100 in PBS for 10 minutes at RT and blocking in 5% fetal calf serum in PBS for 1 hour at RT.
T778 7900-8137 Sentence denotes Incubation with primary antibodies against CK2α (Abcam, ab70774, 1:500), SARS-CoV membrane (M) protein (Rockland, #100-401-A55, 1:500) and SARS-CoV nucleocapsid (N) protein (Rockland, #200-401-A50, 1:1000) was performed for 1 hour at RT.
T779 8138-8408 Sentence denotes After washing with PBS, cells were incubated with AF568-labeled goat-anti-rabbit (Invitrogen, #A11011) and AF647-labeled goat-anti-mouse (Invitrogen, #A21235) secondary antibodies (1:200) as well as AF488-labeled Phalloidin (Hypermol, #8813-01, 1:250) for 2 hours at RT.
T780 8409-8653 Sentence denotes Fluorescence images were generated using a LSM800 confocal laser-scanning microscope (Zeiss) equipped with a 63X, 1.4 NA oil objective and Airyscan detector and the Zen blue software (Zeiss) and processed with Zen blue software and ImageJ/Fiji.
T781 8654-8763 Sentence denotes For 3D-reconstruction, cells were fixed and stained as indicated and imaged as z stack with 0.15 μm sections.
T782 8764-8839 Sentence denotes Z stack was processed using Imaris software 64x 9.5.1 and displayed as MIP.
T783 8840-8990 Sentence denotes To quantify colocalization between casein kinase II and N protein colocalization events in filopodia of SARS-CoV-2 infected Caco-2 cells were counted.
T784 8991-9070 Sentence denotes 42 ± 19 % of the N protein particles detected in filopodia colocalize with CK2.
T785 9071-9134 Sentence denotes Length of filopodia was measured using Metamorph (Version 7.8).
T786 9135-9208 Sentence denotes Distance was measured starting at cortical actin to the tip of Filopodia.
T787 9210-9229 Sentence denotes Electron microscopy
T788 9230-9435 Sentence denotes Vero E6 cells were seeded overnight and then infected for 24 hours with SARS-CoV-2 isolate nCoV-WA1-2020 on silicon chips for scanning electron microscopy or Thermanox for transmission electron microscopy.
T789 9436-9796 Sentence denotes For scanning electron microscopy (SEM), cells were fixed with Karnovsky’s formulation of 2% paraformaldehyde/2.5% glutaraldehyde in 0.1 M Sorenson’s phosphate buffer, and then post-fixed with 1.0% osmium tetroxide/0.8% potassium ferrocyanide in 0.1 M sodium cacodylate buffer washed with 0.1 M sodium cacodylate buffer then stained with 1% tannic acid in dH2O.
T790 9797-9938 Sentence denotes After additional buffer washes, the samples were further osmicated with 2% osmium tetroxide in 0.1M sodium cacodylate, then washed with dH2O.
T791 9939-10443 Sentence denotes Specimens were dehydrated with a graded ethanol series from 50%, 75%, 100% x 3 for 5 minutes each, critical point dried under CO2 in a Bal-Tec model CPD 030 Drier (Balzers, Liechtenstein), mounted with double sided carbon tape on aluminum specimen mounts (Ted Pella), and sputter coated with 35 Å of iridium in a Quorum EMS300T D sputter coater (Electron Microscopy Sciences, Hatfield, PA) prior to viewing at 5 kV in a Hitachi SU-8000 field emission scanning electron microscope (Hitachi, Tokyo, Japan).
T792 10444-10746 Sentence denotes For transmission electron microscopy (TEM), specimens were fixed as described above for scanning electron microscopy and additionally stained overnight with 1% uranyl acetate at 4°C after the second osmium staining and then dehydrated with the same graded ethanol series, and embedded in Spurr’s resin.
T793 10747-10935 Sentence denotes Thin sections were cut with a Leica UC7 ultramicrotome (Buffalo Grove, IL) prior to viewing at 120 kV on a FEI BT Tecnai transmission electron microscope (Thermofisher/FEI, Hillsboro, OR).
T794 10936-11013 Sentence denotes Digital images were acquired with a Gatan Rio camera (Gatan, Pleasanton, CA).
T795 11015-11048 Sentence denotes N overexpression in Vero E6 cells
T796 11049-11279 Sentence denotes The N-protein cassette was subcloned from pLVX-EF1a-SARS-CoV-2-N-2xStrep-IRES-Puro (Gordon et al., 2020) into pLVX-TetOne-Puro (Takara) using the restriction enzymes EcoRI and BamHI to create pLVX-TetOne-Puro-SARS-CoV-2-N-2xStrep.
T797 11280-11344 Sentence denotes Sequence integrity was confirmed by Sanger sequencing (GeneWiz).
T798 11345-11603 Sentence denotes To produce lentiviruses, HEK293T cells (50% confluent in a T175 flask) were transfected with 5 μg of each of the pLVX-TetOne-Puro lentiviral plasmids, 3.33 μg Gag-Pol packaging construct, and 1.66 μg VSV-G envelope (pMD2.G, Addgene) using PolyJet (SignaGen).
T799 11604-11749 Sentence denotes Culture supernatant was precipitated with a final concentration of 8.5% PEG-6000 and 0.3M sodium chloride (NaCl), incubated at 4°C for 2-4 hours.
T800 11750-11884 Sentence denotes Virions were pelleted at 3500 rpm for 20 minutes in a spin bucket rotor, suspended in 0.5 mL 1xPBS, and aliquoted for storage at 80°C.
T801 11885-12078 Sentence denotes Vero E6 cells were seeded in T75 flasks at 50% confluence and transduced with 200 μL precipitated lentivirus derived from pLVX-TetOne-Puro-SARS-CoV-2-N-2xStrep or pLVX-TetOne-Puro empty vector.
T802 12079-12175 Sentence denotes 48 hours post transduction, 10 μg/mL Puromycin was added to cultures to select transduced cells.
T803 12176-12299 Sentence denotes Polyclonal stable cell lines were seeded into 15 cm dishes in triplicate and treated with 1 μg/mL doxycycline for 48 hours.
T804 12300-12372 Sentence denotes Cells were washed in ice cold PBS and harvested by scraping in cold PBS.
T805 12373-12676 Sentence denotes Cell pellets were lysed directly (8 M urea, 100 mM ammonium bicarbonate (ABC), 150 mM NaCl, protease inhibitor (mini-cOmplete, Roche) and phosphatase inhibitors (phosSTOP, Roche), and protein digestion and phosphopeptide enrichment was performed as described above for SARS-CoV-2 infected Vero E6 cells.
T806 12677-12862 Sentence denotes During the analysis, one of three replicates of the N-overexpressed samples was found to be an outlier based on principal component analysis (as in Figures S1A and S1B) and was removed.
T807 12863-12989 Sentence denotes N-overexpression (n = 2) was compared to empty vector (EV) controls (n = 3) during analysis (full data available in Table S1).
T808 12990-13122 Sentence denotes Kinase activity predictions were also performed the same as for viral infection phosphoproteomics (full data available in Table S4).
T809 13124-13143 Sentence denotes Cell cycle analysis
T810 13144-13187 Sentence denotes 1x105 Vero E6 cells were seeded per sample.
T811 13188-13319 Sentence denotes The following day cells were either mock infected or infected with SARS-CoV-2 (isolate BetaCoV/France/IDF0372/2020) at an MOI of 1.
T812 13320-13412 Sentence denotes The samples were incubated for 24 hours before detaching cells using Trypsin 0.05% (Thermo).
T813 13413-13521 Sentence denotes Cells were pelleted at 500x g for 2 minutes, followed by fixation using 4% Formalin (Thermo) for 30 minutes.
T814 13522-13631 Sentence denotes Cells were washed 2x with PBS (Thermo) before permeabilizing using 0.1% Triton X-100 (Thermo) for 20 minutes.
T815 13632-13901 Sentence denotes Finally, cells were pelleted again and incubated with 1 mg/mL 4′,6-diamidino-2-phenylindole (DAPI; Thermo) in PBS for 30 minutes before analyzing cell cycle using fluorescence by flow cytometry using the BD FACSymphony with a violet laser (405 nm) and 450/50 nm filter.
T816 13902-14015 Sentence denotes Gating was performed by first selecting singlets by gating highly correlated cells in an SSC-A versus SSC-H plot.
T817 14016-14092 Sentence denotes Next, typical cellular morphology was gated using a FSC-A versus SSC-A plot.
T818 14093-14188 Sentence denotes These singles were then used to draw histograms which were gated for G0/G1, S, and G2/M phases.
T819 14190-14262 Sentence denotes SARS-CoV-2 infections in ACE2-A549 cells and lysis for cytokine analysis
T820 14263-14389 Sentence denotes Approximately 5 × 105 A549-ACE2 cells were pre-treated with either DMSO or SB203580 (0.01, 0.1, 1, 10 μM final concentration).
T821 14390-14581 Sentence denotes After 1 hour of pre-treatment, cells were infected with SARS-CoV-2 (isolate USA-WA1/2020) at an MOI of 0.1 while maintaining inhibitor concentrations in the media for 30 hours post infection.
T822 14582-14708 Sentence denotes The supernatants from infected cells were analyzed by multiplexed ELISA for the presence of secreted cytokines and chemokines.
T823 14709-14904 Sentence denotes For RNA analysis, cells were lysed in TRIzol and total RNA was extracted and DNase treated using the Direct-zol RNA Miniprep Plus kit (Zymo Research) according to the manufacturer’s instructions.
T824 14905-15026 Sentence denotes For protein analysis, whole cell lysates were obtained by lysis in RIPA buffer and analyzed by SDS-PAGE and western blot.
T825 15028-15053 Sentence denotes Cytokine RT-qPCR analysis
T826 15054-15152 Sentence denotes Gene expression of selected cytokines as well as SARS-CoV-2 replication was quantified by RT-qPCR.
T827 15153-15331 Sentence denotes Reverse transcription of extracted total RNA samples was performed using oligo (dT) primers and SuperScript IV Reverse Transcriptase according to the manufacturer’s instructions.
T828 15332-15493 Sentence denotes Quantitative real-time PCR analysis of cDNA samples was performed using KAPA SYBR FAST qPCR Master Mix (2X) Universal on a LightCycler 480 Instrument II (Roche).
T829 15494-15786 Sentence denotes For viral quantification, primers specifically targeting the subgenomic viral N RNA were used. ΔCT values were determined relative to the ACTB and ΔΔCT values were normalized to the average of mock infected samples (for host genes) or to infected DMSO treated samples (for viral replication).
T830 15787-15887 Sentence denotes Error bars indicate the standard deviation of the mean from three independent biological replicates.
T831 15889-15915 Sentence denotes Multiplexed cytokine ELISA
T832 15916-16381 Sentence denotes Supernatants from infected cells were evaluated for 34 cytokines/chemokines by multiplex ELISA for the following analytes: CCL2/MCP-1, CCL3/MIP-1α, CCL4/MIP-1β, CCL5/RANTES, CCL7/MCP-3, CCL8/MCP-2, CCL11/Eotaxin, CCL13/MCP-4, CCL20/MIP-3α, CXCL1/GROα, CXCL2/GROβ, CXCL5/ENA-78, CXCL8/IL-8, CXCL9/MIG, CXCL10/IP-10, CXCL16, IL-1α, IL-1β, IL-1RA, IL-4, IL-6, IL-7, IL-10, IL-12p70, IL-15, IL-16, IL-17A, IL-22, GM-CSF, MMP-9, S100A8, TNFα, TGFβ, and Trappin-2/Elafin.
T833 16382-16518 Sentence denotes All antibodies and cytokine standards were purchased as antibody pairs from R&D Systems (Minneapolis, MN) or Peprotech (Rocky Hill, NJ).
T834 16519-16677 Sentence denotes Individual magnetic Luminex bead sets (Luminex Corp, CA) were coupled to cytokine-specific capture antibodies according to the manufacturer’s recommendations.
T835 16678-16767 Sentence denotes Samples were analyzed on a Luminex MAGPIX platform and quantified using a standard curve.
T836 16768-16828 Sentence denotes For each bead region, > 50 beads were collected per analyte.
T837 16829-16985 Sentence denotes The median fluorescence intensity of these beads was recorded for each bead and was used for analysis using a custom R script and a 5P regression algorithm.
T838 16987-17066 Sentence denotes SARS-CoV-2 viral quantification via antibody staining in presence of inhibitors
T839 17067-17091 Sentence denotes (Mount Sinai, New York).
T840 17092-17186 Sentence denotes Two thousand (2,000) Vero E6 cells were seeded into 96-well plates and incubated for 24 hours.
T841 17187-17381 Sentence denotes Two hours before infection, the medium was replaced with 100 μL of DMEM (2% FBS) containing the compound of interest at concentrations 50% greater than those indicated, including a DMSO control.
T842 17382-17571 Sentence denotes Plates were then transferred into the BSL-3 facility and 100 PFU of SARS-CoV-2 (MOI 0.025) was added in 50 μL of DMEM (2% FBS), bringing the final compound concentration to those indicated.
T843 17572-17620 Sentence denotes Plates were then incubated for 48 hours at 37°C.
T844 17621-17766 Sentence denotes After infection, supernatants were removed and cells were fixed with 4% formaldehyde for 24 hours prior to being removed from the BSL-3 facility.
T845 17767-17907 Sentence denotes The cells were then immunostained for the viral NP protein (anti-sera produced in the Garcia-Sastre lab; 1:10,000) with a DAPI counterstain.
T846 17908-18018 Sentence denotes Infected cells (488 nM) and total cells (DAPI) were quantified using the Celigo (Nexcelcom) imaging cytometer.
T847 18019-18148 Sentence denotes Infectivity was measured by the accumulation of viral NP protein in the nucleus of the Vero E6 cells (fluorescence accumulation).
T848 18149-18299 Sentence denotes Percent infection was quantified as ((Infected cells/Total cells) - Background) ∗100 and the DMSO control was then set to 100% infection for analysis.
T849 18300-18380 Sentence denotes The IC50 for each experiment was determined using the Prism software (GraphPad).
T850 18381-18528 Sentence denotes For select inhibitors, infected supernatants were assayed for infectious viral titer using the Median Tissue Culture Infectious Dose TCID50 method.
T851 18529-18641 Sentence denotes For this, infectious supernatants were collected at 48 hours post infection and frozen at −80°C until later use.
T852 18642-18724 Sentence denotes Infectious titers were quantified by limiting dilution titration on Vero E6 cells.
T853 18725-18799 Sentence denotes Briefly, Vero E6 cells were seeded in 96-well plates at 20,000 cells/well.
T854 18800-19004 Sentence denotes The next day, SARS-CoV-2-containing supernatant was applied at serial 10-fold dilutions ranging from 10−1 to 10−6 and, after 5 days, viral CPE was detected by staining cell monolayers with crystal violet.
T855 19005-19066 Sentence denotes TCID50/mL was calculated using the method of Reed and Muench.
T856 19068-19102 Sentence denotes Cytotoxicity cell viability assays
T857 19103-19127 Sentence denotes (Mount Sinai, New York).
T858 19128-19234 Sentence denotes Cytotoxicity was also performed using the MTT assay (Roche), according to the manufacturer’s instructions.
T859 19235-19363 Sentence denotes Cytotoxicity was performed in uninfected Vero E6 cells with same compound dilutions and concurrent with viral replication assay.
T860 19364-19430 Sentence denotes All assays were performed in biologically independent triplicates.
T861 19432-19469 Sentence denotes siRNA-based knockdown of host kinases
T862 19470-19496 Sentence denotes (Institut Pasteur, Paris).
T863 19497-19627 Sentence denotes Host kinases were knocked-down in A549 cells stably expressing ACE2 cells using OnTargetPlus siRNA SMARTpools (Horizon Discovery).
T864 19628-19731 Sentence denotes Briefly, A549-ACE2 cells seeded at 2x104 cells/well in 96-well plates 18 hours prior to the experiment.
T865 19732-19906 Sentence denotes The next day, each well was transfected with 6 pmoles of siRNA SMARTpool, using Lipofectamine RNAiMAX (Thermo Fisher Scientific) according to the manufacturer’s instructions.
T866 19907-20045 Sentence denotes Twenty-four (24) hours post transfection, the cell culture supernatant was removed and replaced with virus inoculum (MOI of 0.1 PFU/cell).
T867 20046-20206 Sentence denotes Following a 1 hour adsorption at 37°C, the virus inoculum was removed and replaced with fresh Opti-MEM media (Thermo Fisher Scientific) containing 2% FBS (v/v).
T868 20207-20378 Sentence denotes Seventy-two (72) hours post-infection (p.i.), the cell culture supernatant was heat-inactivated at 95°C for 5 minutes, and detection of viral genomes performed by RT-qPCR.
T869 20380-20449 Sentence denotes SARS-CoV-2 viral quantification via RT-qPCR in presence of inhibitors
T870 20450-20476 Sentence denotes (Institut Pasteur, Paris).
T871 20477-20593 Sentence denotes Detection of viral genomes was performed by RT-qPCR, directly from the inactivated supernatant (Lista et al., 2020).
T872 20594-20650 Sentence denotes SARS-CoV-2 specific primers targeting the N gene region:
T873 20651-20901 Sentence denotes 5′-TAATCAGACAAGGAACTGATTA-3′ (Forward) and 5′-CGAAGGTGTGACTTCCATG-3′ (Reverse) (Chu et al., 2020) were used with the Luna Universal One-Step RT-qPCR Kit (NEB) in an Applied Biosystems QuantStudio 7 thermocycler, with the following cycling conditions:
T874 20902-21004 Sentence denotes 55°C for 10 minutes, 95°C for 1 minute, and 40 cycles of 95°C for 10 s, followed by 60°C for 1 minute.
T875 21005-21180 Sentence denotes The number of viral genomes is expressed as PFU equivalents/mL, and was calculated by performing a standard curve with RNA derived from a viral stock with a known viral titer.
T876 21182-21218 Sentence denotes SARS-CoV-2 titration by plaque assay
T877 21219-21245 Sentence denotes (Institut Pasteur, Paris).
T878 21246-21331 Sentence denotes Vero E6 cells were seeded in 24-well plates at a concentration of 7.5x104 cells/well.
T879 21332-21407 Sentence denotes The following day, serial dilutions were performed in serum-free MEM media.
T880 21408-21629 Sentence denotes After 1 hour absorption at 37°C, 2x overlay media was added to the inoculum to give a final concentration of 2% (v/v) FBS / MEM media and 0.05% (w/v) Agarose (all Thermo Fisher Scientific) to achieve a semi-solid overlay.
T881 21630-21678 Sentence denotes Plaque assays were incubated at 37°C for 3 days.
T882 21679-21806 Sentence denotes Samples were fixed using 4% Formalin (Sigma Aldrich) and plaques were visualized using crystal Violet solution (Sigma Aldrich).
T883 21808-21835 Sentence denotes siRNA Cell viability assays
T884 21836-21862 Sentence denotes (Institut Pasteur, Paris).
T885 21863-22093 Sentence denotes Cell viability in siRNA knocked-down cells was measured using the CellTiter Glo luminescent cell viability assay (Promega) following the manufacturer’s instructions, and luminescence measured in a Tecan Infinity 2000 plate reader.
T886 22094-22249 Sentence denotes Percent viability was calculated relative to untreated cells (100% viability) and cells lysed with 20% ethanol (0% viability), included in each experiment.

2_test

Id Subject Object Predicate Lexical cue
32645325-25724911-20773110 6255-6259 25724911 denotes 2015
32645325-17327847-20773111 6938-6942 17327847 denotes 2007
32645325-32225176-20773112 20587-20591 32225176 denotes 2020
32645325-32031583-20773113 20743-20747 32031583 denotes 2020