PMC:7321036 / 46836-47060 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T376","span":{"begin":22,"end":25},"obj":"Body_part"},{"id":"T377","span":{"begin":201,"end":205},"obj":"Body_part"}],"attributes":[{"id":"A376","pred":"fma_id","subj":"T376","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A377","pred":"fma_id","subj":"T377","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"(I) Small interfering RNA (siRNA) knockdown of p38 pathway genes in A549-ACE2 leads to a significant decrease in SARS-CoV-2 viral replication (red), as assessed by qRT-PCR in the absence of effects on cell viability (black)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T232","span":{"begin":113,"end":121},"obj":"Disease"}],"attributes":[{"id":"A232","pred":"mondo_id","subj":"T232","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"(I) Small interfering RNA (siRNA) knockdown of p38 pathway genes in A549-ACE2 leads to a significant decrease in SARS-CoV-2 viral replication (red), as assessed by qRT-PCR in the absence of effects on cell viability (black)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T579","span":{"begin":59,"end":64},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T580","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0001601"},{"id":"T581","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0050025"},{"id":"T582","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0054264"},{"id":"T583","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0054265"},{"id":"T584","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0054266"},{"id":"T585","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0054267"},{"id":"T586","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0054268"},{"id":"T587","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/CLO_0054269"},{"id":"T588","span":{"begin":87,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T589","span":{"begin":201,"end":205},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"(I) Small interfering RNA (siRNA) knockdown of p38 pathway genes in A549-ACE2 leads to a significant decrease in SARS-CoV-2 viral replication (red), as assessed by qRT-PCR in the absence of effects on cell viability (black)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T329","span":{"begin":124,"end":141},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T330","span":{"begin":124,"end":141},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"(I) Small interfering RNA (siRNA) knockdown of p38 pathway genes in A549-ACE2 leads to a significant decrease in SARS-CoV-2 viral replication (red), as assessed by qRT-PCR in the absence of effects on cell viability (black)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"985","span":{"begin":47,"end":50},"obj":"Gene"},{"id":"986","span":{"begin":73,"end":77},"obj":"Gene"},{"id":"988","span":{"begin":113,"end":123},"obj":"Species"},{"id":"989","span":{"begin":68,"end":72},"obj":"CellLine"}],"attributes":[{"id":"A985","pred":"tao:has_database_id","subj":"985","obj":"Gene:5594"},{"id":"A986","pred":"tao:has_database_id","subj":"986","obj":"Gene:59272"},{"id":"A988","pred":"tao:has_database_id","subj":"988","obj":"Tax:2697049"},{"id":"A989","pred":"tao:has_database_id","subj":"989","obj":"CVCL:0023"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"(I) Small interfering RNA (siRNA) knockdown of p38 pathway genes in A549-ACE2 leads to a significant decrease in SARS-CoV-2 viral replication (red), as assessed by qRT-PCR in the absence of effects on cell viability (black)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T313","span":{"begin":0,"end":224},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"(I) Small interfering RNA (siRNA) knockdown of p38 pathway genes in A549-ACE2 leads to a significant decrease in SARS-CoV-2 viral replication (red), as assessed by qRT-PCR in the absence of effects on cell viability (black)."}