PMC:7321036 / 42877-43253 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T351","span":{"begin":258,"end":262},"obj":"Body_part"}],"attributes":[{"id":"A351","pred":"fma_id","subj":"T351","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":" regulation of CDK2 T14/Y15 phosphorylation, initially increased in response to SARS-CoV-2 infection at 2 h, followed by a decrease over the remainder of the infection time course (Figure 6H, left). CDK2 activity promotes transition from the G2 phase of the cell cycle into mitosis and is inhibited by phosphorylation at positions T14 and Y15 by kinases WEE1 and MYT1, prevent"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T209","span":{"begin":80,"end":88},"obj":"Disease"},{"id":"T210","span":{"begin":91,"end":100},"obj":"Disease"},{"id":"T211","span":{"begin":158,"end":167},"obj":"Disease"}],"attributes":[{"id":"A209","pred":"mondo_id","subj":"T209","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A210","pred":"mondo_id","subj":"T210","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A211","pred":"mondo_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":" regulation of CDK2 T14/Y15 phosphorylation, initially increased in response to SARS-CoV-2 infection at 2 h, followed by a decrease over the remainder of the infection time course (Figure 6H, left). CDK2 activity promotes transition from the G2 phase of the cell cycle into mitosis and is inhibited by phosphorylation at positions T14 and Y15 by kinases WEE1 and MYT1, prevent"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T513","span":{"begin":121,"end":122},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T514","span":{"begin":204,"end":212},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T515","span":{"begin":242,"end":244},"obj":"http://purl.obolibrary.org/obo/CLO_0003414"},{"id":"T516","span":{"begin":258,"end":262},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":" regulation of CDK2 T14/Y15 phosphorylation, initially increased in response to SARS-CoV-2 infection at 2 h, followed by a decrease over the remainder of the infection time course (Figure 6H, left). CDK2 activity promotes transition from the G2 phase of the cell cycle into mitosis and is inhibited by phosphorylation at positions T14 and Y15 by kinases WEE1 and MYT1, prevent"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T300","span":{"begin":1,"end":11},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T301","span":{"begin":28,"end":43},"obj":"http://purl.obolibrary.org/obo/GO_0016310"},{"id":"T302","span":{"begin":242,"end":250},"obj":"http://purl.obolibrary.org/obo/GO_0051319"},{"id":"T303","span":{"begin":258,"end":268},"obj":"http://purl.obolibrary.org/obo/GO_0007049"},{"id":"T304","span":{"begin":274,"end":281},"obj":"http://purl.obolibrary.org/obo/GO_0140014"},{"id":"T305","span":{"begin":274,"end":281},"obj":"http://purl.obolibrary.org/obo/GO_0000278"},{"id":"T306","span":{"begin":289,"end":317},"obj":"http://purl.obolibrary.org/obo/GO_0042326"},{"id":"T307","span":{"begin":302,"end":317},"obj":"http://purl.obolibrary.org/obo/GO_0016310"}],"text":" regulation of CDK2 T14/Y15 phosphorylation, initially increased in response to SARS-CoV-2 infection at 2 h, followed by a decrease over the remainder of the infection time course (Figure 6H, left). CDK2 activity promotes transition from the G2 phase of the cell cycle into mitosis and is inhibited by phosphorylation at positions T14 and Y15 by kinases WEE1 and MYT1, prevent"}

{"project":"LitCovid-PubTator","denotations":[{"id":"889","span":{"begin":15,"end":19},"obj":"Gene"},{"id":"890","span":{"begin":199,"end":203},"obj":"Gene"},{"id":"891","span":{"begin":354,"end":358},"obj":"Gene"},{"id":"892","span":{"begin":363,"end":367},"obj":"Gene"},{"id":"900","span":{"begin":80,"end":100},"obj":"Disease"},{"id":"901","span":{"begin":158,"end":167},"obj":"Disease"},{"id":"902","span":{"begin":274,"end":281},"obj":"Disease"}],"attributes":[{"id":"A889","pred":"tao:has_database_id","subj":"889","obj":"Gene:1017"},{"id":"A890","pred":"tao:has_database_id","subj":"890","obj":"Gene:1017"},{"id":"A891","pred":"tao:has_database_id","subj":"891","obj":"Gene:7465"},{"id":"A892","pred":"tao:has_database_id","subj":"892","obj":"Gene:4661"},{"id":"A900","pred":"tao:has_database_id","subj":"900","obj":"MESH:C000657245"},{"id":"A901","pred":"tao:has_database_id","subj":"901","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" regulation of CDK2 T14/Y15 phosphorylation, initially increased in response to SARS-CoV-2 infection at 2 h, followed by a decrease over the remainder of the infection time course (Figure 6H, left). CDK2 activity promotes transition from the G2 phase of the cell cycle into mitosis and is inhibited by phosphorylation at positions T14 and Y15 by kinases WEE1 and MYT1, prevent"}