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PMC:7321036 / 37258-37605 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T293 116-123 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T294 302-306 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T295 317-322 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T13 302-306 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T166 251-259 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T167 262-271 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T168 302-316 Disease denotes lung carcinoma http://purl.obolibrary.org/obo/MONDO_0005138
T169 307-316 Disease denotes carcinoma http://purl.obolibrary.org/obo/MONDO_0004993

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T343 19-28 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T344 86-90 http://purl.obolibrary.org/obo/CLO_0053428 denotes cAMP
T345 147-151 http://purl.obolibrary.org/obo/CLO_0001757 denotes 1 at
T346 209-219 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T347 291-295 http://purl.obolibrary.org/obo/CLO_0001601 denotes A549
T348 291-295 http://purl.obolibrary.org/obo/CLO_0050025 denotes A549
T349 291-295 http://purl.obolibrary.org/obo/CLO_0054264 denotes A549
T350 291-295 http://purl.obolibrary.org/obo/CLO_0054265 denotes A549
T351 291-295 http://purl.obolibrary.org/obo/CLO_0054266 denotes A549
T352 291-295 http://purl.obolibrary.org/obo/CLO_0054267 denotes A549
T353 291-295 http://purl.obolibrary.org/obo/CLO_0054268 denotes A549
T354 291-295 http://purl.obolibrary.org/obo/CLO_0054269 denotes A549
T355 296-301 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T356 302-306 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T357 302-306 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T358 317-322 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T359 329-333 http://purl.obolibrary.org/obo/CLO_0001601 denotes A549
T360 329-333 http://purl.obolibrary.org/obo/CLO_0050025 denotes A549
T361 329-333 http://purl.obolibrary.org/obo/CLO_0054264 denotes A549
T362 329-333 http://purl.obolibrary.org/obo/CLO_0054265 denotes A549
T363 329-333 http://purl.obolibrary.org/obo/CLO_0054266 denotes A549
T364 329-333 http://purl.obolibrary.org/obo/CLO_0054267 denotes A549
T365 329-333 http://purl.obolibrary.org/obo/CLO_0054268 denotes A549
T366 329-333 http://purl.obolibrary.org/obo/CLO_0054269 denotes A549

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T244 29-36 Chemical denotes phospho http://purl.obolibrary.org/obo/CHEBI_48108
T245 54-61 Chemical denotes phospho http://purl.obolibrary.org/obo/CHEBI_48108
T246 78-85 Chemical denotes phospho http://purl.obolibrary.org/obo/CHEBI_48108
T247 86-90 Chemical denotes cAMP http://purl.obolibrary.org/obo/CHEBI_17489
T248 116-123 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T249 135-142 Chemical denotes phospho http://purl.obolibrary.org/obo/CHEBI_48108
T250 343-345 Chemical denotes 6C http://purl.obolibrary.org/obo/CHEBI_27594

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T242 231-235 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T5 307-316 Phenotype denotes carcinoma http://purl.obolibrary.org/obo/HP_0030731

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
744 37-40 Gene denotes p38 Gene:5594
745 62-65 Gene denotes MK2 Gene:9261
746 125-129 Gene denotes CREB Gene:1385
747 143-148 Gene denotes ATF-1 Gene:466
748 169-177 Gene denotes MAPKAPK2 Gene:9261
749 227-230 Gene denotes p38 Gene:5594
750 275-279 Gene denotes ACE2 Gene:59272
751 324-328 Gene denotes ACE2 Gene:59272
760 296-301 Species denotes human Tax:9606
761 86-90 Chemical denotes cAMP
762 251-271 Disease denotes SARS-CoV-2 infection MESH:C000657245
763 302-316 Disease denotes lung carcinoma MESH:D008175
766 291-295 CellLine denotes A549 CVCL:0023
767 329-333 CellLine denotes A549 CVCL:0023

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T243 0-347 Sentence denotes Immunoblotting for activated phospho-p38 (T180/Y182), phospho-MK2 (T334), and phospho-cAMP response element-binding protein (CREB) and phospho-ATF-1 at their respective MAPKAPK2 sites (S133 in both) confirmed activation of the p38/MAPK pathway during SARS-CoV-2 infection in ACE2-expressing A549 human lung carcinoma cells (ACE2-A549) (Figure 6C).