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PMC:7321036 / 19435-20957 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T143 46-53 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T144 54-61 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T145 74-77 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T146 99-107 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T147 162-170 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T148 227-235 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T149 337-344 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T150 345-352 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T151 423-430 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T152 535-543 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T153 732-740 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T154 767-774 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T155 775-782 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T156 795-798 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T157 837-845 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T158 900-908 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T159 934-942 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T160 1103-1111 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T161 1157-1165 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T162 1216-1224 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T101 23-31 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 303-312 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T103 549-558 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T104 697-705 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T105 745-753 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T106 1384-1393 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T37818 34-39 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T76637 40-53 http://purl.obolibrary.org/obo/PR_000029067 denotes human protein
T69944 93-107 http://purl.obolibrary.org/obo/PR_000029067 denotes human proteins
T77643 125-127 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T26743 326-331 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T76801 708-713 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T10288 714-719 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T39350 756-761 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T96781 831-845 http://purl.obolibrary.org/obo/PR_000029067 denotes human proteins
T23709 863-865 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T92566 1151-1165 http://purl.obolibrary.org/obo/PR_000029067 denotes human proteins
T70112 1210-1224 http://purl.obolibrary.org/obo/PR_000029067 denotes human proteins
T31688 1359-1363 http://purl.obolibrary.org/obo/CLO_0001382 denotes 4, 8
T99883 1398-1399 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T124 46-53 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T125 54-61 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T126 99-107 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T127 162-170 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T128 227-235 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T129 337-344 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T130 345-352 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T131 423-430 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T132 535-543 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T133 767-774 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T134 775-782 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T135 837-845 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T136 900-908 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T137 934-942 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T138 1103-1111 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T139 1157-1165 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T140 1216-1224 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T106 389-404 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T107 443-455 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T108 510-525 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T109 678-693 http://purl.obolibrary.org/obo/GO_0016310 denotes Phosphorylation
T110 1445-1460 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
312 697-707 Species denotes SARS-CoV-2 Tax:2697049
313 714-719 Species denotes Human Tax:9606
319 745-755 Species denotes SARS-CoV-2 Tax:2697049
320 831-836 Species denotes human Tax:9606
321 1151-1156 Species denotes human Tax:9606
322 1210-1215 Species denotes human Tax:9606
323 1384-1393 Disease denotes infection MESH:D007239
329 23-33 Species denotes SARS-CoV-2 Tax:2697049
330 40-45 Species denotes human Tax:9606
331 93-98 Species denotes human Tax:9606
332 303-312 Disease denotes infection MESH:D007239
333 549-558 Disease denotes infection MESH:D007239

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T130 0-193 Sentence denotes The recently published SARS-CoV-2 virus-human protein-protein interaction map identified 332 human proteins interacting with 27 (26 wild-type and 1 mutant) viral proteins (Gordon et al., 2020).
T131 194-325 Sentence denotes Here we found some of these host proteins (40 of 332) to be significantly differentially phosphorylated upon infection (Figure 3 ).
T132 326-496 Sentence denotes Virus-host protein-protein interactions could drive changes in phosphorylation by affecting host protein subcellular localization or by sterically blocking kinase access.
T133 497-668 Sentence denotes Furthermore, phosphorylation of these proteins upon infection may signify an additional mode of functional control over these potential dependency and restriction factors.
T134 669-740 Sentence denotes Figure 3 Phosphorylation on SARS-CoV-2 Virus-Human Interacting Proteins
T135 741-909 Sentence denotes The SARS-CoV-2 virus-host protein-protein interaction map (Gordon et al., 2020) found 332 human proteins interacting with 27 (26 wild-type and 1 mutant) viral proteins.
T136 910-1096 Sentence denotes Here we found 40 of 332 proteins significantly differentially phosphorylated across at least two time points (adjusted p < 0.05 and absolute value of log2 fold change [abs(log2FC)] > 1).
T137 1097-1138 Sentence denotes Viral proteins are shown as red diamonds.
T138 1139-1192 Sentence denotes Interacting human proteins are shown as gray circles.
T139 1193-1418 Sentence denotes PHs emanate from human proteins, colored by their log2 fold change compared with uninfected control samples (red, increase; blue, decrease) at each time point (0, 2, 4, 8, 12, and 24 h after infection) in a clockwise fashion.
T140 1419-1522 Sentence denotes An interactive version of phosphorylation data can be found at https://kroganlab.ucsf.edu/network-maps.