PMC:7321036 / 114146-130142 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T212 191-490 GO:0065007 denotes raujo et al. (1993); Archambault and Carmena (2012); Aubrey et al. (2016); Auld et al. (2005); Bai et al. (1996); Bakircioglu et al. (2011); Bandau et al. (2012); Barkley et al. (2012); Bartrons et al. (2018); Bassermann et al. (2005); Bayliss et al. (2012); Beeson (2013); Beli et al. (2012); Ben D
T213 496-572 SO:0000704 denotes Ouadda et al. (2018); Beurel et al. (2015); Biaoxue et al. (2016); Bieling e
T214 3396-3466 SO:0000704 denotes g et al. (2016); Kumar et al. (2014); Kumar et al. (2018); Kunapuli et
T215 5896-5929 SO:0000704 denotes ght et al. (2004); Ravichandran e
T216 9250-9404 GO:0065007 denotes richment.Abundance tab), and phosphorylation dynamics clusters (from Figure 4A) upon SARS-CoV-2 infection (Enrichment.Ph_Clusters tab). Column description
T217 10144-10153 GO:0065007 denotes regulated
T243 10181-10191 SP_7 denotes SARS-CoV-2
T247 10198-10199 NCBITaxon:10239 denotes i
T250 10206-10207 NCBITaxon:10239 denotes r
T261 10256-10257 PG_3 denotes P
T263 10262-10263 NCBITaxon:11118 denotes a
T264 10266-10268 SO:0000417 denotes as
T265 10270-10271 PG_4 denotes o
T267 10284-10285 SP_7 denotes a
T299 10369-10370 SP_10 denotes o
T300 10370-10371 PG_4 denotes r
T312 10384-10385 PG_4 denotes p
T314 10400-10401 SP_7 denotes s
T322 10418-10419 GO:0018995 denotes h
T332 10467-10475 SP_7 denotes RS-CoV-2
T334 10477-10478 SP_7 denotes a
T336 10478-10479 GO:0018995 denotes t
T337 10479-10480 SP_6;NCBITaxon:9606 denotes h
T342 10520-10521 PG_4 denotes i
T343 10523-10525 GO:0006396 denotes on
T350 10535-10536 SO:0000203 denotes g
T354 10541-10542 SP_7 denotes o
T356 10542-10543 NCBITaxon:10239 denotes l
T363 10544-10545 MOP:0000780 denotes g
T364 10550-10552 GO:0005643 denotes co
T365 10552-10553 PR:000011526 denotes n
T382 10569-10570 GO:0006260 denotes P
T383 10570-10571 NCBITaxon:10239 denotes r
T384 10571-10572 SO:0001026 denotes e
T390 10587-10592 GO:0039703 denotes ption
T396 10601-10602 GO:0030532 denotes c
T397 10602-10604 GO:0005840 denotes ti
T402 10605-10609 PR:000000045 denotes itie
T406 10614-10619 GO:0065007 denotes lated
T408 10625-10627 GO:0065007 denotes gu
T419 10657-10658 GO:0006915 denotes t
T420 10663-10665 GO:0006260 denotes ri
T421 10665-10671 SO:0001811 denotes ption
T426 10690-10692 GO:0008150 denotes ro
T428 10696-10698 SP_7 denotes A-
T430 10718-10724 SP_7 denotes -CoV-2
T431 10725-10726 NCBITaxon:10239 denotes i
T453 10778-10779 GO:0000165 denotes l
T466 10806-10807 GO:0051235 denotes E
T495 10834-10835 PR:000008800 denotes 9
T498 10838-10839 CHEBI:23888;CHEBI:23888 denotes G
T510 10853-10854 GO:0006338 denotes E
T511 10854-10855 GO:0032991 denotes S
T514 10859-10861 GO:0065007 denotes re
T516 10873-10874 SO:0005836;GO:0065007 denotes l
T517 10876-10878 SO:0005836 denotes es
T518 10885-10886 PR:000008800 denotes p
T521 10887-10888 GO:0005680 denotes c
T523 10888-10889 GO:0065007 denotes t
T524 10889-10890 GO:0005856 denotes e
T539 10900-10901 PR:000000125 denotes 7
T554 10931-10933 CL:0011108;UBERON:0002424 denotes te
T577 10956-10957 GO:0065007 denotes r
T578 10957-10958 SP_7 denotes o
T591 10968-10971 PG_4 denotes pro
T596 10981-10991 SP_7 denotes SARS-CoV-2
T597 10995-10996 CL_6 denotes e
T599 11001-11003 CL_1 denotes AC
T601 11004-11005 SP_7 denotes 2
T604 11005-11006 SP_7 denotes -
T636 11034-11037 PR:000008220 denotes p38
T637 11038-11047 CHEBI:35222;CHEBI:35222 denotes inhibitor
T638 11062-11063 SP_7 denotes r
T640 11072-11074 CL_6 denotes ro
T641 11080-11081 SP_7 denotes c
T643 11097-11098 SP_7 denotes v
T650 11138-11139 GO:0031941 denotes t
T657 11158-11159 PR:000005952 denotes S
T670 11207-11209 CHEBI:51461;CHEBI:51461 denotes S5
T673 11232-11233 CL_6 denotes r
T674 11235-11236 SP_7 denotes s
T679 11262-11263 PR:000001245 denotes o
T680 11279-11280 GO:0010467 denotes i
T687 11324-11325 GO:0010467 denotes n
T693 11346-11347 GO:0065007 denotes u
T697 11358-11359 GO:0007050 denotes e
T707 11382-11383 BV_13 denotes g
T710 11385-11386 CHEBI:32958;CHEBI:32958 denotes s
T712 11389-11391 CHEBI:32958;CHEBI:32958 denotes pp
T717 11402-11403 SP_7 denotes s
T726 11413-11414 PR:000008814 denotes s
T728 11414-11417 PR:000002087 denotes upp
T730 11417-11419 GO:0065007 denotes li
T731 11427-11428 NCBITaxon:10239 denotes l
T735 11431-11432 GO:0000165 denotes n
T740 11444-11446 BV_27 denotes bl
T742 11453-11455 GO:0000165 denotes nn
T746 11471-11472 SP_7 denotes s
T747 11474-11475 CL_6 denotes e
T749 11480-11481 PR:000004986;CL_2 denotes c
T756 11495-11496 CHEBI:35222;CHEBI:35222 denotes i
T758 11501-11502 SP_7 denotes s
T763 11527-11528 SP_7 denotes v
T764 11529-11530 CL_6 denotes r
T791 11584-11586 SP_7 denotes ar
T796 11617-11618 SP_7 denotes R
T798 11626-11627 SP_7 denotes a
T801 11643-11644 CHEBI:35224;CHEBI:35224 denotes e
T804 11676-11677 SP_6;NCBITaxon:9606 denotes u
T805 11677-11678 UBERON:0002048 denotes g
T806 11684-11685 SP_6;NCBITaxon:9606 denotes n
T807 11685-11686 UBERON:0000483 denotes i
T808 11686-11688 UBERON:0002048 denotes ng
T811 11696-11697 UBERON:0002031;CL:0002328 denotes e
T812 11701-11702 GO:0065007 denotes d
T813 11703-11704 PR:000008220 denotes p
T822 11729-11732 PR:000000134 denotes owl
T826 11748-11749 SP_7 denotes s
T827 11749-11750 SO:0001026 denotes e
T833 11766-11768 GO:0042571 denotes by
T842 11791-11793 PR:000008220 denotes 39
T846 11818-11819 CHEBI:23888;CHEBI:23888 denotes u
T864 11851-11852 GO:0065007 denotes I
T871 11865-11866 PR:000017403 denotes 1
T880 11892-11893 SP_7 denotes 2
T883 11899-11900 CHEBI:51231;CHEBI:51231 denotes P
T886 11900-11901 GO:0051318 denotes 0
T888 11901-11902 GO:0051318 denotes 1
T906 11945-11946 SP_7 denotes 2
T937 11984-11985 CHEBI:36357;CHEBI:36357 denotes M
T938 11985-11987 PR:000010154 denotes 13
T941 12003-12004 PR:000010152 denotes 1
T943 12005-12006 PR:000010154 denotes 3
T946 12006-12007 SP_7 denotes 2
T952 12019-12021 CHEBI:35222;CHEBI:35222 denotes to
T954 12026-12027 SO:0000646 denotes M
T966 12043-12044 CHEBI:35222;CHEBI:35222 denotes o
T968 12055-12056 GO:0065007 denotes d
T972 12062-12063 SP_7 denotes 2
T981 12100-12101 CL_6 denotes r
T985 12109-12110 PR:000005951 denotes c
T994 12127-12128 PR:000010152 denotes 1
T1000 12130-12131 G_3;PG_10;PR:000003622 denotes 2
T1007 12138-12139 SO:0000646 denotes t
T1010 12141-12142 SO:0000704 denotes N
T1024 12157-12158 PR:000000103;GO:0000187 denotes a
T1025 12158-12159 GO:0000187 denotes n
T1027 12163-12166 CHEBI:36357;CHEBI:36357 denotes M.S
T1030 12170-12172 GO:0042571 denotes by
T1034 12198-12200 PR:000005950 denotes cs
T1037 12217-12222 GO:0031012 denotes xcell
T1038 12224-12225 GO:0019722 denotes c
T1039 12230-12231 SP_7 denotes R
T1040 12237-12238 SP_6;NCBITaxon:9606 denotes h
T1053 12263-12264 PR:000010152 denotes 1
T1054 12264-12265 PR:000008220 denotes 3
T1061 12275-12276 PR:000003622;G_3;PG_10 denotes 2
T1064 12276-12277 SP_7 denotes 2
T1074 12282-12283 SP_7 denotes v
T1075 12283-12286 GO:0006260 denotes ati
T1076 12294-12295 GO:0065007 denotes i
T1078 12298-12299 PR:000012719 denotes I
T1082 12304-12305 CHEBI:36357;CHEBI:36357 denotes u
T1083 12305-12306 CHEBI:35222;CHEBI:35222 denotes t
T1095 12333-12334 CHEBI:35222;CHEBI:35222 denotes b
T1099 12365-12366 NCBITaxon:10239;GO:0006260 denotes r
T1100 12367-12369 GO:0006260 denotes Re
T1104 12378-12379 GO:0006412 denotes r
T1108 12409-12410 NCBITaxon:10239 denotes A
T1110 12412-12413 SP_7 denotes -
T1111 12413-12414 CHEBI:23888;CHEBI:23888 denotes s
T1112 12414-12415 CHEBI:36357;CHEBI:36357 denotes u
T1113 12419-12422 GO:0065007 denotes ted
T1115 12425-12426 GO:0000165 denotes n
T1116 12426-12427 PR:000002190 denotes t
T1119 12438-12441 GO:0005856 denotes len
T1123 12453-12455 CHEBI:10545;CHEBI:10545 denotes en
T1124 12463-12464 GO:0019012;NCBITaxon:10239 denotes r
T1125 12471-12472 NCBITaxon:10239 denotes S
T1126 12474-12475 NCBITaxon:7742 denotes v
T1127 12475-12476 NCBITaxon:10376 denotes e
T1136 12489-12492 PR:000010849 denotes S;
T1138 12503-12504 SP_7 denotes S
T1139 12505-12506 SP_7 denotes 2
T1149 12522-12523 CHEBI:35222;CHEBI:35222 denotes o
T1155 12543-12547 NCBITaxon:11120 denotes ents
T1174 12586-12590 SP_7 denotes 1359
T1176 12598-12599 GO:0065007 denotes o
T1177 12602-12604 NCBITaxon:10239 denotes ra
T1180 12617-12618 PR:000008220 denotes P
T1185 12623-12624 NCBITaxon:7719 denotes F
T1197 12662-12663 PR:000008220 denotes p
T1203 12679-12680 PR:000008220 denotes 3
T1204 12694-12695 PR:000008220 denotes P
T1207 12710-12711 NCBITaxon:9606 denotes h
T1215 12729-12730 CL:0000763 denotes y
T1219 12743-12745 GO:0065007 denotes ea
T1220 12746-12747 GO:0005622;GO:0035556 denotes c
T1221 12747-12748 GO:0035556 denotes h
T1225 12777-12778 CHEBI:35222;CHEBI:35222 denotes n
T1226 12789-12792 GO:0065007 denotes lan
T1230 12798-12799 SP_7 denotes c
T1231 12800-12801 DG_28 denotes d
T1232 12801-12802 CHEBI:35222;CHEBI:35222 denotes o
T1233 12805-12808 GO:0006412 denotes ion
T1234 12808-12809 CHEBI:35222;CHEBI:35222 denotes s
T1238 12837-12838 GO:0009987 denotes o
T1243 12852-12853 CHEBI:36357;CHEBI:36357 denotes c
T1244 12865-12866 SP_7 denotes v
T1250 12880-12881 CHEBI:52217;CHEBI:52217 denotes m
T1256 12882-12883 CL_6 denotes r
T1257 12883-12884 CHEBI:23888;CHEBI:23888 denotes g
T1260 12894-12895 NCBITaxon:9986 denotes i
T1262 12897-12898 NCBITaxon:10088 denotes s
T1265 12901-12903 NCBITaxon:10088 denotes se
T1266 12911-12912 PR:000004397 denotes a
T1268 12915-12917 GO:0016020 denotes AN
T1280 12950-12951 CHEBI:75958;CHEBI:75958 denotes t
T1284 12969-12970 CHEBI:30059;CHEBI:30059 denotes n
T1288 13196-13198 GO:0042571 denotes ni
T1289 13201-13202 GO:0042571 denotes y
T1291 13207-13208 GO:0042571 denotes d
T1292 13209-13212 GO:0042571 denotes cat
T1294 13212-13214 GO:0042571 denotes io
T1295 13214-13215 GO:0042571 denotes n
T1296 13217-13219 GO:0042571 denotes nd
T1300 13227-13228 GO:0042571 denotes h
T1302 13231-13232 PR:000002123 denotes M
T1303 13232-13233 GO:0042571 denotes B
T1307 13237-13238 GO:0042571 denotes o
T1308 13241-13244 GO:0042571 denotes tat
T1309 13244-13245 PR:000001395 denotes i
T1310 13245-13246 GO:0042571 denotes o
T1312 13246-13247 GO:0042571 denotes n
T1316 13259-13260 GO:0042571 denotes n
T1320 13266-13269 GO:0042571 denotes ant
T1326 13278-13279 GO:0042571 denotes B
T1328 13281-13282 GO:0042571 denotes o
T1329 13292-13294 GO:0042571 denotes by
T1330 13296-13297 GO:0042571 denotes h
T1331 13297-13298 PR:000006071 denotes e
T1332 13299-13300 GO:0042571 denotes I
T1333 13300-13303 GO:0042571 denotes ntr
T1335 13307-13308 GO:0042571 denotes a
T1337 13325-13326 PR:000002121 denotes m
T1340 13343-13344 PR:000002123 denotes 1
T1344 13357-13358 PR:000002124 denotes 1
T1346 13361-13362 PR:000001992 denotes 3
T1347 13370-13371 PR:000006064 denotes 0
T1352 13381-13382 GO:0042571 denotes a
T1359 13397-13398 GO:0042571 denotes A
T1361 13401-13402 GO:0042571 denotes r
T1365 13403-13404 GO:0042571 denotes y
T1367 13405-13408 GO:0042571 denotes and
T1380 13440-13443 GO:0042571 denotes and
T1383 13453-13456 GO:0042571 denotes and
T1384 13457-13459 GO:0042571 denotes by
T1386 13463-13464 GO:0042571 denotes d
T1400 13516-13517 SP_7 denotes V
T1401 13518-13519 CL_6 denotes r
T1403 13587-13588 SP_7 denotes v
T1404 13588-13589 SO:0001026 denotes e
T1406 13592-13593 UBERON:0002048 denotes g
T1407 13603-13605 CL_7 denotes e
T1411 13605-13606 CL_4 denotes H
T1415 13612-13614 SP_6;NCBITaxon:9606 denotes Hu
T1417 13615-13616 SP_6;NCBITaxon:9606 denotes h
T1420 13619-13620 SP_6;NCBITaxon:9606;PG_10 denotes M
T1421 13620-13621 PG_10;PR:000003622 denotes e
T1424 13629-13630 SO:0001031 denotes s
T1431 13773-13774 CHEBI:10545;CHEBI:10545 denotes r
T1438 13830-13833 CL_6 denotes ver
T1441 13844-13845 CHEBI:16526;CHEBI:16526 denotes o
T1442 13855-13856 NCBITaxon:27592 denotes o
T1444 13857-13859 G_3;PG_10;PR:000003622 denotes ac
T1456 13871-13872 CL:0011108 denotes s
T1460 13894-13895 SP_6;NCBITaxon:9606 denotes n
T1463 13945-13947 SP_7 denotes s.
T1470 14016-14017 CHEBI:50144;CHEBI:50144 denotes r
T1471 14017-14019 CHEBI:46756;CHEBI:46756 denotes es
T1475 14090-14091 SP_7 denotes r
T1479 14114-14115 SO:0000704 denotes i
T1483 14152-14153 SP_7 denotes o
T1496 14182-14183 CHEBI:18219;CHEBI:18219 denotes B
T1499 14184-14185 CHEBI:50329;CHEBI:50329 denotes E
T1518 14304-14305 CHEBI:30751;CHEBI:30751 denotes F
T1538 14563-14564 UBERON:0001977 denotes u
T1541 14570-14572 GO:0016020 denotes M.
T1552 14620-14621 UBERON:0001851 denotes l
T1553 14623-14624 CHEBI:10545;CHEBI:10545 denotes C
T1556 14632-14634 CHEBI:10545;CHEBI:10545 denotes er
T1557 14636-14638 CHEBI:10545;CHEBI:10545 denotes en
T1558 14638-14639 CHEBI:10545;CHEBI:10545 denotes t
T1559 14644-14645 CHEBI:64276;CHEBI:64276 denotes R
T1584 14748-14749 CL_4 denotes K
T1592 14788-14789 GO:0009293 denotes R
T1603 14815-14816 CHEBI:18219;CHEBI:18219 denotes b
T1627 14889-14890 GO:0000279 denotes M
T1636 14915-14919 BV_21 denotes L.S.
T1640 14935-14937 BV_27 denotes se
T1658 14990-14991 PR:000002123 denotes i
T1667 14991-14993 PR:000002139 denotes on
T1697 14997-14998 GO:0042571 denotes S
T1702 15021-15022 NCBITaxon:10239 denotes L
T1705 15025-15026 CL_6 denotes E
T1713 15057-15058 CHEBI:51231;CHEBI:51231 denotes i
T1732 15119-15120 GO:0010467 denotes R
T1736 15129-15132 GO:0009294 denotes ect
T1737 15132-15133 SO:0000646 denotes r
T1754 15207-15208 SO:0001026 denotes S
T1760 15234-15235 CHEBI:2511;CHEBI:2511 denotes G
T1775 15467-15469 SO:0001811 denotes he
T1776 15501-15502 SP_6;NCBITaxon:9606 denotes a
T1785 15535-15536 NCBITaxon:6239 denotes c
T1788 15539-15540 NCBITaxon:9606 denotes i
T1793 15569-15570 NCBITaxon:9606 denotes B
T1802 15664-15667 SO:0001811 denotes rti
T1804 15781-15783 CHEBI:32958;CHEBI:32958 denotes Ph
T1811 15868-15869 GO:0006468 denotes l
T1812 15869-15870 GO:0043234 denotes s
T1813 15870-15876 GO:0043234 denotes pring
T1814 15883-15886 GO:0043234 denotes nce
T1816 15892-15895 GO:0032991 denotes xes
T1817 15896-15897 GO:0032991 denotes P
T1819 15907-15908 GO:0032991 denotes p
T1821 15921-15922 GO:0032991 denotes o
T1822 15934-15936 GO:0032991 denotes be
T1827 15967-15968 UBERON:0002048;CL:0000082 denotes g
T43 11231-11236 CHEBI:36044;CHEBI:36044 denotes Drugs
T44 11241-11250 CHEBI:36357;CHEBI:36357 denotes compounds
T573 15127-15135 CHEBI:10545;CHEBI:10545 denotes Electron

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T50 8351-8356 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 8511-8518 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T52 8760-8767 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T53 8794-8799 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T54 8980-8988 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T55 9099-9103 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T56 9229-9236 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T57 9631-9638 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T58 10694-10697 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T59 10740-10744 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T60 10745-10749 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T61 10838-10842 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T62 10868-10872 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T63 10902-10910 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T64 11011-11016 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T65 11085-11090 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T66 11113-11122 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T67 11123-11133 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T68 11371-11378 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T69 11480-11484 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T70 11555-11559 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T71 14618-14622 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T72 14931-14934 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T73 15061-15064 Body_part denotes Map http://purl.org/sig/ont/fma/fma67847

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T34 10740-10744 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T395 8362-8370 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T396 8373-8382 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T397 8454-8462 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T398 8465-8474 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T399 9335-9343 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T400 9346-9355 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T401 9565-9574 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T402 9580-9588 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T403 9604-9619 Disease denotes Viral Infection http://purl.obolibrary.org/obo/MONDO_0005108
T404 9610-9619 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T405 10181-10189 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T406 10192-10201 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T407 10465-10473 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T408 10714-10722 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T409 10981-10989 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T410 12380-12389 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T411 12448-12457 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T412 12888-12898 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T413 13397-13404 Disease denotes Allergy http://purl.obolibrary.org/obo/MONDO_0005271
T414 13409-13419 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T415 13916-13924 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T416 14145-14154 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T417 14657-14666 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T119 394-398 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T120 485-488 http://purl.obolibrary.org/obo/CLO_0001926 denotes Ben
T121 511-515 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T122 1128-1131 http://purl.obolibrary.org/obo/CLO_0002421 denotes Cho
T123 1128-1131 http://purl.obolibrary.org/obo/CLO_0052479 denotes Cho
T124 1128-1131 http://purl.obolibrary.org/obo/CLO_0052480 denotes Cho
T125 1128-1131 http://purl.obolibrary.org/obo/CLO_0052483 denotes Cho
T126 1128-1131 http://purl.obolibrary.org/obo/CLO_0052484 denotes Cho
T127 1128-1131 http://purl.obolibrary.org/obo/CLO_0052485 denotes Cho
T128 1296-1300 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T129 1458-1462 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T130 1762-1766 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T131 2067-2071 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T132 2346-2350 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T133 2769-2777 http://purl.obolibrary.org/obo/CLO_0037163 denotes Ishikawa
T134 3448-3452 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T135 3807-3809 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T136 3807-3809 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T137 3831-3833 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T138 3831-3833 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T139 3851-3853 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T140 3851-3853 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T141 3870-3872 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T142 3870-3872 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T143 3889-3891 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T144 3889-3891 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T145 3907-3909 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T146 3907-3909 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T147 3925-3927 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T148 3925-3927 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T149 4875-4879 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T150 5024-5026 http://purl.obolibrary.org/obo/CLO_0007815 denotes Mo
T151 5405-5408 http://purl.obolibrary.org/obo/NCBITaxon_9596 denotes Pan
T152 5434-5438 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T153 5526-5534 http://purl.obolibrary.org/obo/CLO_0008423 denotes Pfeiffer
T154 5847-5851 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T155 6029-6033 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T156 6053-6057 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T157 6298-6302 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T158 6443-6447 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T159 6895-6899 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T160 7744-7748 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T161 8257-8259 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T162 8343-8356 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T163 8786-8799 http://purl.obolibrary.org/obo/CLO_0051719 denotes Vero E6 cells
T164 8892-8894 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T165 8892-8894 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T166 9096-9098 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T167 9099-9103 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T168 9464-9474 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activities
T169 9529-9539 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T170 9697-9707 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T171 9724-9725 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T172 9747-9751 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T173 9915-9925 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T174 10053-10055 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T175 10284-10285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T176 10600-10610 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activities
T177 10678-10688 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T178 10734-10739 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T179 10740-10744 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T180 10740-10744 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T181 10745-10755 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T182 10838-10842 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T183 10868-10878 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T184 11006-11010 http://purl.obolibrary.org/obo/CLO_0001601 denotes A549
T185 11006-11010 http://purl.obolibrary.org/obo/CLO_0050025 denotes A549
T186 11006-11010 http://purl.obolibrary.org/obo/CLO_0054264 denotes A549
T187 11006-11010 http://purl.obolibrary.org/obo/CLO_0054265 denotes A549
T188 11006-11010 http://purl.obolibrary.org/obo/CLO_0054266 denotes A549
T189 11006-11010 http://purl.obolibrary.org/obo/CLO_0054267 denotes A549
T190 11006-11010 http://purl.obolibrary.org/obo/CLO_0054268 denotes A549
T191 11006-11010 http://purl.obolibrary.org/obo/CLO_0054269 denotes A549
T192 11011-11016 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T193 11085-11090 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T194 11110-11112 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T195 11145-11147 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T196 11207-11209 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T197 11228-11230 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T198 11272-11282 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T199 11339-11341 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T200 11466-11470 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T201 11480-11489 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T202 11499-11504 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T203 11555-11559 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T204 11720-11722 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T205 12405-12406 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T206 13039-13040 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T207 13927-13932 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T208 14416-14421 http://purl.obolibrary.org/obo/CLO_0001627 denotes A., A
T209 14555-14560 http://purl.obolibrary.org/obo/CLO_0001627 denotes A., A
T210 14618-14622 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T211 14949-14950 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T212 15350-15353 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T213 15436-15439 http://purl.obolibrary.org/obo/CLO_0051582 denotes has

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T71797 151-155 Chemical denotes Amin http://purl.obolibrary.org/obo/CHEBI_32952
T62738 485-488 Chemical denotes Ben http://purl.obolibrary.org/obo/CHEBI_33783
T56646 2186-2189 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T20906 3554-3557 Chemical denotes Lau http://purl.obolibrary.org/obo/CHEBI_32359
T3769 3807-3809 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T30886 3831-3833 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T69538 3851-3853 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T25132 3870-3872 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T50510 3889-3891 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T55911 3907-3909 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T99919 3925-3927 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T18641 4028-4031 Chemical denotes Lin http://purl.obolibrary.org/obo/CHEBI_32386
T93865 4047-4050 Chemical denotes Lin http://purl.obolibrary.org/obo/CHEBI_32386
T11122 4260-4262 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T53901 4278-4280 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T45081 5024-5026 Chemical denotes Mo http://purl.obolibrary.org/obo/CHEBI_28685
T1537 5145-5147 Chemical denotes Na http://purl.obolibrary.org/obo/CHEBI_26708
T78468 8511-8518 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T91318 8760-8767 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T26822 8892-8894 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T72017 8980-8988 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T77191 9051-9053 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T37437 9229-9236 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T65490 9444-9446 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T61100 9631-9638 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T43215 10053-10055 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T649 10127-10129 Chemical denotes S8 http://purl.obolibrary.org/obo/CHEBI_29385
T57781 11038-11047 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T84757 11048-11056 Chemical denotes SB203580 http://purl.obolibrary.org/obo/CHEBI_90705
T22546 11158-11160 Chemical denotes S8 http://purl.obolibrary.org/obo/CHEBI_29385
T40458 11207-11209 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T92142 11221-11223 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T29633 11228-11230 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T32084 11290-11292 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T81403 11339-11341 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T98259 11371-11378 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T51993 11674-11678 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T91938 11720-11722 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T68283 12246-12249 Chemical denotes ERA http://purl.obolibrary.org/obo/CHEBI_51451
T21380 13013-13015 Chemical denotes ID http://purl.obolibrary.org/obo/CHEBI_141439
T92160 13503-13505 Chemical denotes La http://purl.obolibrary.org/obo/CHEBI_33336
T27672 13877-13879 Chemical denotes Ho http://purl.obolibrary.org/obo/CHEBI_49648
T53882 15419-15421 Chemical denotes La http://purl.obolibrary.org/obo/CHEBI_33336

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T41 8260-8275 http://purl.obolibrary.org/obo/GO_0016310 denotes Phosphorylation
T42 8417-8432 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T43 8601-8616 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T44 8731-8746 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T45 8901-8916 http://purl.obolibrary.org/obo/GO_0016310 denotes Phosphorylation
T46 9151-9166 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T47 9279-9294 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T48 9522-9539 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activities
T49 9604-9619 http://purl.obolibrary.org/obo/GO_0016032 denotes Viral Infection
T50 9690-9707 http://purl.obolibrary.org/obo/GO_0016301 denotes Kinase activities
T51 9908-9925 http://purl.obolibrary.org/obo/GO_0016301 denotes Kinase activities
T52 10068-10083 http://purl.obolibrary.org/obo/GO_0016310 denotes Phosphorylation
T53 10144-10169 http://purl.obolibrary.org/obo/GO_0042325 denotes regulated phosphorylation
T54 10154-10169 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T55 10384-10399 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T56 10476-10488 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T57 10490-10505 http://purl.obolibrary.org/obo/GO_0016310 denotes Phosphorylation
T58 10579-10610 http://purl.obolibrary.org/obo/GO_0003700 denotes Transcription Factor Activities
T59 10579-10599 http://purl.obolibrary.org/obo/GO_0000981 denotes Transcription Factor
T60 10579-10592 http://purl.obolibrary.org/obo/GO_0006351 denotes Transcription
T61 10657-10688 http://purl.obolibrary.org/obo/GO_0003700 denotes transcription factor activities
T62 10657-10677 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T63 10657-10670 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T64 11265-11282 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activities
T65 11310-11325 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T66 11371-11386 http://purl.obolibrary.org/obo/GO_0006605 denotes protein targets
T67 12390-12402 http://purl.obolibrary.org/obo/GO_0009405 denotes Pathogenesis
T68 14618-14628 http://purl.obolibrary.org/obo/GO_0007049 denotes Cell Cycle

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T16 13397-13404 Phenotype denotes Allergy http://purl.obolibrary.org/obo/HP_0012393
T17 15747-15755 Phenotype denotes Oncology http://purl.obolibrary.org/obo/HP_0002664

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T968 0-20 Sentence denotes Supporting Citations
T969 21-85 Sentence denotes The following references appear in the Supplemental Information:
T970 86-8224 Sentence denotes Abraham et al. (2000); Alfonso et al. (2011); Ali et al. (2000); Amin et al. (2014); Aoh et al. (2009); Araujo et al. (1993); Archambault and Carmena (2012); Aubrey et al. (2016); Auld et al. (2005); Bai et al. (1996); Bakircioglu et al. (2011); Bandau et al. (2012); Barkley et al. (2012); Bartrons et al. (2018); Bassermann et al. (2005); Bayliss et al. (2012); Beeson (2013); Beli et al. (2012); Ben Djoudi Ouadda et al. (2018); Beurel et al. (2015); Biaoxue et al. (2016); Bieling et al. (2008); Bischoff et al. (1990); Bitko et al. (2008); Blethrow et al. (2008); Böck et al. (2010); Boeing et al. (2016); Bradshaw et al. (2013); Brattsand et al. (1994); Bromberg and Darnell (2000); Bruinsma et al. (2014); Byon et al. (1998); Cahill et al. (2016a); Cahill et al. (2016b); Cai et al. (2006); Cai et al. (2007); Casado et al. (2014); Chang et al. (2004); Chen et al. (1999); Chen et al. (2002); Chen et al. (2004); Chen et al. (2009); Chen et al. (2013); Chen et al. (2017); Cheng et al. (1998); Cheng et al. (2000); Chiu et al. (2012); Cho et al. (2019); Chou et al. (1990); Chu et al. (2012); Corkery et al. (2015); Costa-Mattioli et al. (2004); Courcelles et al. (2013); Cox et al. (2003); Das et al. (2018); Das et al. (2019); Day et al. (2010); de Haan and Rottier (2005); Decker and Kovarik (2000); DeDiego et al. (2011); DeDiego et al. (2014); Degryse et al. (2018); Deora et al. (2004); Dephoure et al. (2008); Díaz-Moreno et al. (2009); Dou et al. (2015); Eguchi et al. (2009); Elia et al. (2015); Ellis et al. (2019); Eriksson et al. (2004); Escobar et al. (2015); Eto et al. (2012); Eulalio et al. (2007); Fallahi et al. (2016); Fan et al. (1997); Fan et al. (2018); Fang et al. (2000); Farquar et al. (2008); Feldman et al. (1997); Fleming et al. (2000); Folker et al. (2005); Foltz et al. (2009); Formstecher et al. (2001); Franchin et al. (2015); Frémin et al. (2016); Fujimoto et al. (2017); Gagnon and Delpire (2010); Gao and Luo (2006); Garcia-Moreno et al. (2018); Geuens et al. (2017); Gherzi et al. (2004); Goel et al. (2015); Goldstein et al. (2000); Grzenda et al. (2009); Guo et al. (2017); Hajjar (1991); Hajjar et al. (1994); Halder and Johnson (2011); Handschick et al. (2014); Harder et al. (2014); He et al. (2010); He et al. (2018); Heald and McKeon (1990); Heaton et al. (2016); Hedglin and Benkovic (2015); Hein and Nilsson (2016); Hensley and Kursula (2016); Holz et al. (2005); Hou et al. (2011); Hu et al. (2010); Hu et al. (2013); Hu et al. (2015); Huang and Lai (2001); Huang et al. (2006); Huang et al. (2014); Hwang et al. (2014); Ichimura et al. (2005); Inoki et al. (2002); Inoue et al. (2011); Intine et al. (2003); Ishii et al. (2013); Ishikawa et al. (2015); Izawa and Inagaki (2006); Jacque and Stevenson (2006); Jang et al. (2015); Jiang et al. (2014); Johnson et al. (2011); Kane et al. (2002); Kanzawa et al. (2006); Karin (1995); Kastenhuber and Lowe (2017); Katayama et al. (2004); Kennedy et al. (2017); Khurana and Bhattacharyya (2015); Killoran et al. (2015); Kim et al. (2006); Kindrachuk et al. (2015); Kishimoto et al. (2003); Kjolby et al. (2010); Koff et al. (1992); Kohl et al. (2019); Koseki et al. (1999); Kostenko et al. (2009); Kotula et al. (2013); Kovacina et al. (2003); Kraft et al. (2003); Kramer et al. (1998); Kremer et al. (2007); Kuang et al. (2016); Kumar et al. (2014); Kumar et al. (2018); Kunapuli et al. (2006); Labit et al. (2012); Lamarche-Vane and Hall (1998); Larance et al. (2010); Lau et al. (2006); Law et al. (2007); Le Sage et al. (2016); Lee and Myung (2008); Lee et al. (2011); Lee et al. (2012); Lee et al. (2013); Leite and Way (2015); Lekmine et al. (2003); Lekmine et al. (2004); Leukel and Jost (1995); Levy and Lee (2002); Li and Martinez (2011); Li and Nagy (2011); Li et al. (2007a); Li et al. (2007b); Li et al. (2008); Li et al. (2016); Li et al. (2017); Liang et al. (2016); Liao et al. (2005); Lieberman et al. (2017); Lim et al. (2013); Lin et al. (2009); Lin et al. (2013); Lingel et al. (2017); Lisnock et al. (2000); Liu and Schneider (2013); Liu et al. (2011); Liu et al. (2013); Liu et al. (2015); Lobry et al. (2007); Lokireddy et al. (2015); Long et al. (2014); Lu et al. (2014); Lu et al. (2017); Lubas et al. (2011); Luciani et al. (2000); Lukas et al. (2011); Luo et al. (2005); Ly et al. (2014); Ly et al. (2017); Machado-Neto et al. (2014); Machowska et al. (2015); Madureira et al. (2012); Magnuson et al. (2012); Magron et al. (2015); Mahony et al. (2017); Mancini et al. (2017); Mandl et al. (2005); Manning and Toker (2017); Marcos-Villar et al. (2016); Marklund et al. (1993); Marklund et al. (1996); Marquette et al. (2011); Matsuhashi et al. (2019); Matsumoto et al. (2015); Matsuoka et al. (2003); McCamphill et al. (2015); McClain et al. (2002); Mehellou et al. (2018); Meier and Blobel (1990); Meier and Blobel (1992); Meier and Blobel 1992); Mendoza et al. (2011); Menon et al. (2014); Mizutani et al. (2004); Mo et al. (2012); Moldave (1985); Morris et al. (2017); Muda et al. (1996); Mueller et al. (2007); Müller et al. (2014); Na et al. (2015); Nairn et al. (2001); Nandi et al. (2007); Needham et al. (2019); Nielsen et al. (2001); Ogiso et al. (2004); Ohtsubo et al. (1995); Old et al. (2009); Olsen et al. (2006); Olsen et al. (2010); Oshiro et al. (2007); Palamarchuk et al. (2005); Pan (2010); Paquette et al. (2018); Park et al. (2000); Parplys et al. (2015); Patel et al. (2015); Penzo et al. (2019); Pfeiffer et al. (2011); Pires et al. (2017); Ponnam et al. (2019); Popov (2012); Poppe et al. (2017); Potter et al. (2002); Potthoff and Olson (2007); Preisinger et al. (2004); Proteau et al. (2005); Qiao et al. (2016); Qiu et al. (2016); Radic (2016); Radtke et al. (2006); Radulescu and Cleveland (2010); Rahim et al. (2018); Rai et al. (2017); Ramm et al. (2006); Raught et al. (2004); Ravichandran et al. (2001); Rebeaud et al. (2008); Renganathan et al. (2005); Revenko et al. (2010); Riad et al. (2018); Robinson et al. (2018); Robinson-White and Stratakis (2002); Robitaille et al. (2013); Rogalla et al. (1999); Rogers et al. (2015); Roy et al. (2014); Roy et al. (2017); Ryan et al. (2016); Salvi et al. (2009); Sanborn et al. (2011); Sánchez-Martín and Komatsu (2018); Santamaria et al. (2003); Saredi et al. (1997); Schmucker and Sumara (2014); Schweppe et al. (2013); Sengupta et al. (2013); Shah et al. (2018); Shahbazian et al. (2006); Shandilya et al. (2014); Sharma et al. (2011); Sharma et al. (2014); Shi and Sun (2015); Shi et al. (2008); Shih et al. (2012); Sinclair et al. (2006); Smith and Enquist (2002); Snyder et al. (2004); Stoilov et al. (2004); Stokoe et al. (1992); Su et al. (2001); Tacke et al. (1998); Tafforeau et al. (2011); Tan et al. (2004); Tan et al. (2012); Tanenbaum et al. (2006); Tantos et al. (2013); Tarakhovsky and Prinjha (2018); Tavares et al. (2015); Tee et al. (2002); Thaker et al. (2019); Thejer et al. (2020); Tiedje et al. (2015); Tokuyama et al. (2001); Toughiri et al. (2013); Trencia et al. (2003); Trigg and Ferguson (2015); Tsai and Seto (2002); Tsai et al. (1993); Tsoi et al. (2014); Tsvetkov and Stern (2005); Ui et al. (2015); Ujike and Taguchi (2015); Valvezan and Klein (2012); Vind et al. (2011); Vishwanatha and Kumble (1993); Wada et al. (2001); Walter et al. (2002); Walter et al. (2016); Wang and Prives (1995); Wang and Zhang (1999); Wang et al. (2000); Wang et al. (2007); Wang et al. (2008); Wang et al. (2013); Wang et al. (2020); Ward et al. (2004); Wen et al. (1995); Wertz et al. (2015); Willems et al. (1996); Williams et al. (1997); Wohlbold et al. (2012); Wolin and Cedervall (2002); Wortzel and Seger (2011); Wu et al. (2014); Wu et al. (2018); Wurm et al. (2001); Xu et al. (2011); Yang et al. (2012a); Yang et al. (2012b); Yang et al (2014); Yao et al. (2017); Ye et al. (2008); Yim et al. (2013); Yoo et al. (2019); Yu et al. (2009); Yu et al. (2011); Yu et al. (2012); Yui et al. (2001); Zhang et al. (1998); Zhang et al. (2009); Zhang et al. (2015); Zhang et al. (2019a); Zhang et al. (2019b); Zhao et al. (2015); Zhou et al. (2016); Zhu et al. (2001); Zhu et al. (2017); Zou et al. (2007); Zuo and Manley (1993).
T971 8226-8250 Sentence denotes Supplemental Information
T972 8251-8315 Sentence denotes Table S1 Phosphorylation and Abundance Data, Related to Figure 1
T973 8316-8383 Sentence denotes Contains proteomic data of Vero E6 cells upon SARS-CoV-2 infection.
T974 8384-8689 Sentence denotes Find the full list of unfiltered phosphorylation sites occurring upon SARS-CoV-2 infection (PhosphoDataFull tab), full list of protein abundance measurements (AbundanceDataFull tab), and filtered list of all detected phosphorylation sites collapsed into single-site measurements (PhosphoDataFiltered tab).
T975 8690-8833 Sentence denotes Lastly, find the full list of unfiltered phosphorylation sites upon N protein overexpression in Vero E6 cells (PhosphoNOverexpressionFull tab).
T976 8834-8885 Sentence denotes Column descriptions are indicated in the final tab.
T977 8886-8943 Sentence denotes Table S2 Viral Phosphorylation Sites, Related to Figure 2
T978 8944-9044 Sentence denotes List of phosphosites found on viral proteins from this study as well as from Davidson et al. (2020).
T979 9045-9098 Sentence denotes Table S3 Enrichments, Related to Figures 1, 4, and S1
T980 9099-9385 Sentence denotes Gene ontology enrichments for significantly changed phosphorylation sites (Enrichment.Phosphorylation tab), significantly changed protein abundance (Enrichment.Abundance tab), and phosphorylation dynamics clusters (from Figure 4A) upon SARS-CoV-2 infection (Enrichment.Ph_Clusters tab).
T981 9386-9437 Sentence denotes Column descriptions are indicated in the final tab.
T982 9438-9495 Sentence denotes Table S4 Predicted Kinase Activities, Related to Figure 4
T983 9496-9603 Sentence denotes Full results of predicted kinase activities for each time point post infection with SARS-CoV-2 (Kinase Act.
T984 9604-9666 Sentence denotes Viral Infection tab) and N protein overexpression (Kinase Act.
T985 9667-9689 Sentence denotes N Overexpression tab).
T986 9690-9907 Sentence denotes Kinase activities are inferred as a -log10(p value) of Z-test from the comparison of fold changes in phosphosite measurements of the known substrates against the overall distribution of fold changes across the sample.
T987 9908-9994 Sentence denotes Kinase activities possessing any absolute value change greater than 1.5 are indicated.
T988 9995-10046 Sentence denotes Column descriptions are indicated in the final tab.
T989 10047-10129 Sentence denotes Table S5 Prioritized Phosphorylation Site Review, Related to Figure 7 and Table S8
T990 10130-10332 Sentence denotes Significantly regulated phosphorylation sites upon SARS-CoV-2 infection prioritized as either annotated within the PhosphoSitePlus database or possessing a high functional score (> = 0.75) (Ochoa et al.
T991 10333-10339 Sentence denotes 2020).
T992 10340-10489 Sentence denotes Includes literature context for prioritized phosphorylation sites, including their known functions and proposed relevance to SARS-CoV-2 pathogenesis.
T993 10490-10559 Sentence denotes Phosphorylation sites are partitioned into eight biological contexts.
T994 10560-10631 Sentence denotes Table S6 Predicted Transcription Factor Activities, Related to Figure 6
T995 10632-10787 Sentence denotes Full results of computed transcription factor activities from RNA-seq analysis of SARS-CoV-2 infected human lung cell lines (GSE147507) (Blanco-Melo et al.
T996 10788-10830 Sentence denotes 2020) using DoRothEA (Garcia-Alonso et al.
T997 10831-10837 Sentence denotes 2019).
T998 10838-10892 Sentence denotes Gene symbols, NES scores, and cell lines are depicted.
T999 10893-10946 Sentence denotes Table S7 Cytokine Profiling Data, Related to Figure 6
T1000 10947-11057 Sentence denotes Results from Luminex profiling of SARS-CoV-2 infected ACE2-A549 cells pre-treated with p38 inhibitor SB203580.
T1001 11058-11134 Sentence denotes Supernatants from infected cells were evaluated for 34 cytokines/chemokines.
T1002 11135-11151 Sentence denotes Units are pg/mL.
T1003 11152-11230 Sentence denotes Table S8 Drugs and Compounds, Related to Figures 7 and S5 and Tables S4 and S5
T1004 11231-11343 Sentence denotes Drugs and compounds mapped to top kinase activities (Table S4) and prioritized phosphorylation sites (Table S5).
T1005 11344-11608 Sentence denotes DrugInfo tab depicts known protein targets, approval status, SMILES, supplier, catalog numbers, chembl IDs, annotation of test site and cell line in which tests were performed, IC50 (viral inhibition) and CC50 (cell viability) values for pharmacological profiling.
T1006 11609-11723 Sentence denotes FullDrugResponseData tab depicts mean and standard deviation for drug screening experiments depicted in Figure S5.
T1007 11725-11740 Sentence denotes Acknowledgments
T1008 11741-13493 Sentence denotes This research was funded by grants from the 10.13039/100000002National Institutes of Health (P50AI150476, U19AI135990, U19AI135972, R01AI143292, R01AI120694, P01A1063302, and R01AI122747 to N.J.K.; 1R01CA221969 and 1R01CA244550 to K.M.S.; R01GM133981 to D.L.S.; 1F32CA236347-01 to J.E.M.; U19AI118610 to J.R.J.; and F32CA239333 to M.B.), Defense Advance Research Projects Agency HR0011-19-2-0020 (to N.J.K., A.G.S., and K.M.S.); by the Laboratory for Genomics Research (LGR) Excellence in Research Award (ERA) from the 10.13039/100014220Innovative Genomics Institute at UC Berkeley (grant number 133122P); by CRIP (Center for Research for Influenza Pathogenesis), a NIAID-supported Center of Excellence for Influenza Research and Surveillance (CEIRS; contract HHSN272201400008C) (to A.G.S.); by supplements to 10.13039/100000060NIAID grant U19AI135972 and DoD grant W81XWH-19-PRMRP-FPA (to A.G.S.); and by the generous support of the 10.13039/100007457JPB Foundation, the Open Philanthropy Project (research grant 2020-215611 [5384]), and other philanthropic donations (to A.G.S.); by the Laboratoire d’Excellence “Integrative Biology of Emerging Infectious Diseases” grant ANR-10-LABX-62-IBEID (to M.V.); by the DFG under Germany's Excellence Strategy (EXC-2189, project ID 390939984 to R.G.); by a Starting Grant Award from the 10.13039/501100000781European Research Council (ERC-2014-STG 638884 PhosFunc to P.B.); by the 10.13039/501100002347Federal Ministry of Education and Research (BMBF, Computational Life Sciences grant 031L0181B to J.S.R.); by the Intramural Research Program of the 10.13039/100000002NIH, 10.13039/100000060National Institute of Allergy and Infectious Diseases (to E.R.F. and E.D.W.); and by funding from 10.13039/100007013F.
T1009 13494-13571 Sentence denotes Hoffmann-La Roche and Vir Biotechnology and gifts from The Ron Conway Family.
T1010 13572-13637 Sentence denotes K.M.S. is an investigator of the Howard Hughes Medical Institute.
T1011 13638-13827 Sentence denotes The views, opinions, and findings contained in this study are those of the authors and do not represent the official views, policies, or endorsement of the Department of Defense or the U.S.
T1012 13828-13839 Sentence denotes Government.
T1013 13840-13947 Sentence denotes We would like to acknowledge Desiree Ho, Innovative Genomics Institute, for SARS-CoV-2 virus illustrations.
T1014 13948-14077 Sentence denotes We thank Randy Albert for support with the BSL3 facility and procedures at the Icahn School of Medicine at Mount Sinai, New York.
T1015 14079-14099 Sentence denotes Author Contributions
T1016 14100-14422 Sentence denotes Conceptualization, M.B., D.L.S., and N.J.K.; Infection Experiments, B.M., V.V.R., B.E.N., L.M., C.K., Q.D.T., A.H., T.V., K.M.W., and E.M.; Proteomics Sample Coordination and Preparation, E.S., M.S., J.M.F., J.Z.G., and J.X.; Proteomics Data Acquisition, A.L.R. and D.L.S.; Data Analysis, M.C.M., B.J.P., D.M., C.H.-A., A.
T1017 14423-14433 Sentence denotes Dunham, M.
T1018 14434-14561 Sentence denotes Modak, D.Q., Y.Z., J.R.J., D.L.S., P.B., J.K.L., M.G., M.B., and C.J.P.M.; Figure Generation, M.C.M., B.J.P., D.M., C.H.-A., A.
T1019 14562-14572 Sentence denotes Dunham, M.
T1020 14573-14828 Sentence denotes Modak, D.Q., J.R.J., D.L.S., P.B., and M.B.; Cell Cycle Experiments, R.R. and B.M.; Infection Imaging, S.W., J.K., S.U., G.K., and R.G.; Manuscript Preparation, M.B., D.E.G., K.O., J.R.J., D.L.S., P.B., N.J.K., and R.D.M.; Literature Review, by R.M.K., M.
T1021 14829-14874 Sentence denotes Modak, J.B., A.R., T.P., Q.L., R.H., M.C., M.
T1022 14875-14951 Sentence denotes Muralidharan, M.K., G.J., B.T., J.H., D.L.S., and M.B.; RNA-seq Analysis, A.
T1023 14952-15301 Sentence denotes Dugourd, A.V., and J.S.-R.; Drug Curation, Y.S., J.E.M., K.M.S., A.R.L., E.J.M., E.F., and S.B.; Interactive Map, T.M., M.C.O., Y.C., J.C.J.C., D.J.B, S.K., M.B., and R.M.K.; Electron Microscopy, E.R.F. and E.D.w.; Work Supervision, T.K., J.K.L., A.G., B.S., M.O., J.S.-R., G.K., R.G., B.R.t., K.M.S., J.R.J., D.L.S., A.G.-S., M.V., P.B., and N.J.K.
T1024 15303-15327 Sentence denotes Declaration of Interests
T1025 15328-15409 Sentence denotes The Krogan laboratory has received research support from Vir Biotechnology and F.
T1026 15410-15428 Sentence denotes Hoffmann-La Roche.
T1027 15429-15531 Sentence denotes K.M.S. has consulting agreements for the following companies involving cash and/or stock compensation:
T1028 15532-15799 Sentence denotes Black Diamond Therapeutics, BridGene Biosciences, Denali Therapeutics, Dice Molecules, eFFECTOR Therapeutics (zotatifin and tomivosertib), Erasca, Genentech/Roche, Janssen Pharmaceuticals, Kumquat Biosciences, Kura Oncology, Merck, Mitokinin, Petra Pharma, Qulab Inc.
T1029 15800-15904 Sentence denotes Revolution Medicines (WDB002), Type6 Therapeutics, Venthera, and Wellspring Biosciences (Araxes Pharma).
T1030 15905-15996 Sentence denotes Supplemental Information can be found online at https://doi.org/10.1016/j.cell.2020.06.034.