PMC:7319613 / 4650-5532
Annnotations
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T73 | 24-32 | SP_7 | denotes | COVID-19 |
| T74 | 51-60 | MOP:0000568 | denotes | oxidative |
| T75 | 75-84 | MOP:0000568 | denotes | oxidative |
| T76 | 142-152 | GO:0065007 | denotes | regulation |
| T77 | 243-252 | MOP:0000568 | denotes | Oxidative |
| T78 | 281-289 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | oxidized |
| T79 | 290-303 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
| T80 | 325-333 | SP_7 | denotes | COVID-19 |
| T81 | 342-347 | UBERON:0000170 | denotes | lungs |
| T82 | 349-357 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | Oxidized |
| T83 | 358-371 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
| T84 | 392-403 | GO:0050817 | denotes | coagulation |
| T85 | 426-434 | CL:0000233 | denotes | platelet |
| T86 | 488-496 | SP_7 | denotes | COVID-19 |
| T87 | 534-542 | SP_7 | denotes | COVID-19 |
| T88 | 602-611 | MOP:0000568 | denotes | oxidative |
| T89 | 729-737 | SP_7 | denotes | COVID-19 |
| T90 | 774-783 | MOP:0000568 | denotes | oxidative |
| T91 | 808-819 | GO:0007567 | denotes | prematurity |
| T79446 | 24-32 | SP_7 | denotes | COVID-19 |
| T97104 | 51-60 | MOP:0000568 | denotes | oxidative |
| T588 | 75-84 | MOP:0000568 | denotes | oxidative |
| T3518 | 142-152 | GO:0065007 | denotes | regulation |
| T20606 | 243-252 | MOP:0000568 | denotes | Oxidative |
| T20774 | 281-289 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | oxidized |
| T1362 | 290-303 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
| T87866 | 325-333 | SP_7 | denotes | COVID-19 |
| T66042 | 342-347 | UBERON:0000170 | denotes | lungs |
| T4721 | 349-357 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | Oxidized |
| T89600 | 358-371 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
| T43418 | 392-403 | GO:0050817 | denotes | coagulation |
| T82797 | 426-434 | CL:0000233 | denotes | platelet |
| T81388 | 488-496 | SP_7 | denotes | COVID-19 |
| T88622 | 534-542 | SP_7 | denotes | COVID-19 |
| T2753 | 602-611 | MOP:0000568 | denotes | oxidative |
| T37382 | 729-737 | SP_7 | denotes | COVID-19 |
| T83273 | 774-783 | MOP:0000568 | denotes | oxidative |
| T53875 | 808-819 | GO:0007567 | denotes | prematurity |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T9 | 290-303 | Body_part | denotes | phospholipids | http://purl.org/sig/ont/fma/fma82779 |
| T10 | 342-347 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T11 | 358-371 | Body_part | denotes | phospholipids | http://purl.org/sig/ont/fma/fma82779 |
| T12 | 426-434 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T20 | 0-12 | Disease | denotes | Inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T21 | 24-32 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T22 | 114-126 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T23 | 325-333 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T24 | 488-496 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T25 | 534-542 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T26 | 729-737 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T22 | 128-129 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T23 | 342-347 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T6 | 281-303 | Chemical | denotes | oxidized phospholipids | http://purl.obolibrary.org/obo/CHEBI_60156 |
| T7 | 290-303 | Chemical | denotes | phospholipids | http://purl.obolibrary.org/obo/CHEBI_16247 |
| T8 | 358-371 | Chemical | denotes | phospholipids | http://purl.obolibrary.org/obo/CHEBI_16247 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 97 | 334-341 | Species | denotes | patient | Tax:9606 |
| 98 | 290-303 | Chemical | denotes | phospholipids | MESH:D010743 |
| 99 | 358-371 | Chemical | denotes | phospholipids | MESH:D010743 |
| 100 | 0-12 | Disease | denotes | Inflammation | MESH:D007249 |
| 101 | 24-32 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 102 | 114-126 | Disease | denotes | inflammation | MESH:D007249 |
| 103 | 325-333 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 104 | 392-417 | Disease | denotes | coagulation abnormalities | MESH:D025861 |
| 105 | 488-496 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 106 | 534-542 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 107 | 729-737 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T15 | 51-67 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
| T16 | 75-91 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
| T17 | 243-259 | Phenotype | denotes | Oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
| T18 | 392-417 | Phenotype | denotes | coagulation abnormalities | http://purl.obolibrary.org/obo/HP_0001928 |
| T19 | 422-441 | Phenotype | denotes | low platelet counts | http://purl.obolibrary.org/obo/HP_0001873 |
| T20 | 602-618 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
| T21 | 774-790 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T7 | 0-12 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | Inflammation |
| T8 | 114-126 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T9 | 142-152 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T10 | 392-403 | http://purl.obolibrary.org/obo/GO_0050817 | denotes | coagulation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T28 | 0-127 | Sentence | denotes | Inflammation related to COVID-19 further increases oxidative stress, while oxidative stress, in turn, can promote inflammation. |
| T29 | 128-242 | Sentence | denotes | A basal redox regulation deficit thus might increase the risk to get trapped in this detrimental feedforward loop. |
| T30 | 243-348 | Sentence | denotes | Oxidative stress furthermore leads to oxidized phospholipids, commonly present in COVID-19 patient lungs. |
| T31 | 349-522 | Sentence | denotes | Oxidized phospholipids have been linked to coagulation abnormalities and low platelet counts, which are associated with adverse outcome of COVID-19 (Merad and Martin, 2020). |
| T32 | 523-738 | Sentence | denotes | Given that COVID-19 risk factors/conditions are commonly characterized by high oxidative stress levels it seems plausible that redox balance deficits are among the underlying mechanisms of vulnerability to COVID-19. |
| T33 | 739-882 | Sentence | denotes | Therefore, the potentially altered oxidative stress status linked to prematurity must be considered as it might exacerbate the clinical status. |