PMC:7319613 / 4650-5532
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T73 | 24-32 | SP_7 | denotes | COVID-19 |
T74 | 51-60 | MOP:0000568 | denotes | oxidative |
T75 | 75-84 | MOP:0000568 | denotes | oxidative |
T76 | 142-152 | GO:0065007 | denotes | regulation |
T77 | 243-252 | MOP:0000568 | denotes | Oxidative |
T78 | 281-289 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | oxidized |
T79 | 290-303 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
T80 | 325-333 | SP_7 | denotes | COVID-19 |
T81 | 342-347 | UBERON:0000170 | denotes | lungs |
T82 | 349-357 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | Oxidized |
T83 | 358-371 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
T84 | 392-403 | GO:0050817 | denotes | coagulation |
T85 | 426-434 | CL:0000233 | denotes | platelet |
T86 | 488-496 | SP_7 | denotes | COVID-19 |
T87 | 534-542 | SP_7 | denotes | COVID-19 |
T88 | 602-611 | MOP:0000568 | denotes | oxidative |
T89 | 729-737 | SP_7 | denotes | COVID-19 |
T90 | 774-783 | MOP:0000568 | denotes | oxidative |
T91 | 808-819 | GO:0007567 | denotes | prematurity |
T79446 | 24-32 | SP_7 | denotes | COVID-19 |
T97104 | 51-60 | MOP:0000568 | denotes | oxidative |
T588 | 75-84 | MOP:0000568 | denotes | oxidative |
T3518 | 142-152 | GO:0065007 | denotes | regulation |
T20606 | 243-252 | MOP:0000568 | denotes | Oxidative |
T20774 | 281-289 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | oxidized |
T1362 | 290-303 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
T87866 | 325-333 | SP_7 | denotes | COVID-19 |
T66042 | 342-347 | UBERON:0000170 | denotes | lungs |
T4721 | 349-357 | MOP:0000568;CHEBI:60156;CHEBI:60156 | denotes | Oxidized |
T89600 | 358-371 | CHEBI:60156;CHEBI:60156 | denotes | phospholipids |
T43418 | 392-403 | GO:0050817 | denotes | coagulation |
T82797 | 426-434 | CL:0000233 | denotes | platelet |
T81388 | 488-496 | SP_7 | denotes | COVID-19 |
T88622 | 534-542 | SP_7 | denotes | COVID-19 |
T2753 | 602-611 | MOP:0000568 | denotes | oxidative |
T37382 | 729-737 | SP_7 | denotes | COVID-19 |
T83273 | 774-783 | MOP:0000568 | denotes | oxidative |
T53875 | 808-819 | GO:0007567 | denotes | prematurity |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T9 | 290-303 | Body_part | denotes | phospholipids | http://purl.org/sig/ont/fma/fma82779 |
T10 | 342-347 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T11 | 358-371 | Body_part | denotes | phospholipids | http://purl.org/sig/ont/fma/fma82779 |
T12 | 426-434 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T20 | 0-12 | Disease | denotes | Inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T21 | 24-32 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T22 | 114-126 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T23 | 325-333 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T24 | 488-496 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T25 | 534-542 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T26 | 729-737 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T22 | 128-129 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T23 | 342-347 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T6 | 281-303 | Chemical | denotes | oxidized phospholipids | http://purl.obolibrary.org/obo/CHEBI_60156 |
T7 | 290-303 | Chemical | denotes | phospholipids | http://purl.obolibrary.org/obo/CHEBI_16247 |
T8 | 358-371 | Chemical | denotes | phospholipids | http://purl.obolibrary.org/obo/CHEBI_16247 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
97 | 334-341 | Species | denotes | patient | Tax:9606 |
98 | 290-303 | Chemical | denotes | phospholipids | MESH:D010743 |
99 | 358-371 | Chemical | denotes | phospholipids | MESH:D010743 |
100 | 0-12 | Disease | denotes | Inflammation | MESH:D007249 |
101 | 24-32 | Disease | denotes | COVID-19 | MESH:C000657245 |
102 | 114-126 | Disease | denotes | inflammation | MESH:D007249 |
103 | 325-333 | Disease | denotes | COVID-19 | MESH:C000657245 |
104 | 392-417 | Disease | denotes | coagulation abnormalities | MESH:D025861 |
105 | 488-496 | Disease | denotes | COVID-19 | MESH:C000657245 |
106 | 534-542 | Disease | denotes | COVID-19 | MESH:C000657245 |
107 | 729-737 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T15 | 51-67 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
T16 | 75-91 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
T17 | 243-259 | Phenotype | denotes | Oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
T18 | 392-417 | Phenotype | denotes | coagulation abnormalities | http://purl.obolibrary.org/obo/HP_0001928 |
T19 | 422-441 | Phenotype | denotes | low platelet counts | http://purl.obolibrary.org/obo/HP_0001873 |
T20 | 602-618 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
T21 | 774-790 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T7 | 0-12 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | Inflammation |
T8 | 114-126 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T9 | 142-152 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
T10 | 392-403 | http://purl.obolibrary.org/obo/GO_0050817 | denotes | coagulation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T28 | 0-127 | Sentence | denotes | Inflammation related to COVID-19 further increases oxidative stress, while oxidative stress, in turn, can promote inflammation. |
T29 | 128-242 | Sentence | denotes | A basal redox regulation deficit thus might increase the risk to get trapped in this detrimental feedforward loop. |
T30 | 243-348 | Sentence | denotes | Oxidative stress furthermore leads to oxidized phospholipids, commonly present in COVID-19 patient lungs. |
T31 | 349-522 | Sentence | denotes | Oxidized phospholipids have been linked to coagulation abnormalities and low platelet counts, which are associated with adverse outcome of COVID-19 (Merad and Martin, 2020). |
T32 | 523-738 | Sentence | denotes | Given that COVID-19 risk factors/conditions are commonly characterized by high oxidative stress levels it seems plausible that redox balance deficits are among the underlying mechanisms of vulnerability to COVID-19. |
T33 | 739-882 | Sentence | denotes | Therefore, the potentially altered oxidative stress status linked to prematurity must be considered as it might exacerbate the clinical status. |