> top > docs > PMC:7318948 > spans > 16190-16941 > annotations

PMC:7318948 / 16190-16941 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T235 30-34 PR:000001393 denotes IL-6
T236 64-72 SP_7 denotes COVID-19
T237 166-170 PR:000001393 denotes IL-6
T238 218-223 NCBITaxon:10239 denotes viral
T239 319-324 NCBITaxon:10239 denotes viral
T240 410-414 PR:000001393 denotes IL-6
T241 448-458 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T242 490-507 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T243 583-600 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T244 686-694 SP_7 denotes COVID-19
T245 728-733 NCBITaxon:10239 denotes virus
T246 734-738 GO:0018995 denotes host
T82799 30-34 PR:000001393 denotes IL-6
T96738 64-72 SP_7 denotes COVID-19
T48035 166-170 PR:000001393 denotes IL-6
T78381 218-223 NCBITaxon:10239 denotes viral
T73784 319-324 NCBITaxon:10239 denotes viral
T46486 410-414 PR:000001393 denotes IL-6
T69420 448-458 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T27409 490-507 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T63247 583-600 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T56582 686-694 SP_7 denotes COVID-19
T43770 728-733 NCBITaxon:10239 denotes virus
T95404 734-738 GO:0018995 denotes host

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T90 534-542 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T84 64-72 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 686-694 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T212 171-177 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T213 203-204 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T214 305-306 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T215 728-733 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T174 30-32 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T176 166-168 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T178 410-412 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T180 448-458 Chemical denotes tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049|http://purl.obolibrary.org/obo/CHEBI_61057

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
396 30-34 Gene denotes IL-6 Gene:3569
397 166-170 Gene denotes IL-6 Gene:3569
398 410-414 Gene denotes IL-6 Gene:3569
399 242-250 Species denotes patients Tax:9606
400 363-371 Species denotes patients Tax:9606
401 448-458 Chemical denotes tacrolimus MESH:D016559
402 64-72 Disease denotes COVID-19 MESH:C000657245
403 686-694 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T33 534-548 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T36 171-190 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T37 178-190 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T38 728-750 http://purl.obolibrary.org/obo/GO_0019048 denotes virus-host interaction

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T145 0-136 Sentence denotes One of the main concerns with IL-6 blockade in the treatment of COVID-19, however, is the appropriate timing of when to start treatment.
T146 137-238 Sentence denotes It is possible that blocking IL-6 signal transduction can lead to a reduction in viral clearance [3].
T147 239-372 Sentence denotes In patients that are already immunosuppressed, this could lead to a much higher viral load as compared with immunocompetent patients.
T148 373-459 Sentence denotes Additionally, we do not know whether IL-6 alters the levels of circulating tacrolimus.
T149 460-561 Sentence denotes This may suggest cessation of immunosuppressive therapy until the initial cytokine storm as resolved.
T150 562-751 Sentence denotes Temporary removal of immunosuppressive regiment is likely beneficial for transplant recipients because clinical outcomes of COVID-19 seems to mostly dependent on the virus-host interaction.