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PMC:7318948 / 1069-2416 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T23 95-103 SP_7 denotes COVID-19
T24 126-132 GO:0016265 denotes deaths
T25 181-192 NCBITaxon:11118 denotes Coronavirus
T26 299-307 SP_7 denotes COVID-19
T27 316-322 GO:0016265 denotes deaths
T28 372-380 SP_7 denotes COVID-19
T29 437-449 UBERON:0001852 denotes endotracheal
T30 608-616 SP_7 denotes COVID-19
T31 651-656 UBERON:0000062 denotes organ
T32 750-758 SP_7 denotes COVID-19
T33 808-826 CHEBI:35705;CHEBI:35705 denotes immunosuppressants
T34 926-931 NCBITaxon:10239 denotes viral
T35 1032-1045 PR:000001393 denotes interleukin-6
T36 1047-1051 PR:000001393 denotes IL-6
T37 1080-1084 UBERON:0002048;GO:0030324 denotes lung
T38 1085-1091 GO:0006281 denotes repair
T39 1102-1107 NCBITaxon:10239 denotes viral
T40 1142-1146 PR:000001393 denotes IL-6
T41 1147-1156 CHEBI:35222;CHEBI:35222 denotes inhibitor
T42 1157-1162 CHEBI:23888;CHEBI:23888 denotes drugs
T43 1210-1218 SP_7 denotes COVID-19
T44 1237-1243 UBERON:0002113 denotes kidney
T45 1248-1253 UBERON:0002107 denotes liver
T46 1288-1292 PR:000001393 denotes IL-6
T47 1293-1302 CHEBI:35222;CHEBI:35222 denotes inhibitor
T26793 95-103 SP_7 denotes COVID-19
T17320 126-132 GO:0016265 denotes deaths
T29874 181-192 NCBITaxon:11118 denotes Coronavirus
T65188 299-307 SP_7 denotes COVID-19
T18243 316-322 GO:0016265 denotes deaths
T75932 372-380 SP_7 denotes COVID-19
T83510 437-449 UBERON:0001852 denotes endotracheal
T83503 608-616 SP_7 denotes COVID-19
T80946 651-656 UBERON:0000062 denotes organ
T2797 750-758 SP_7 denotes COVID-19
T18817 808-826 CHEBI:35705;CHEBI:35705 denotes immunosuppressants
T49695 926-931 NCBITaxon:10239 denotes viral
T30614 1032-1045 PR:000001393 denotes interleukin-6
T71673 1047-1051 PR:000001393 denotes IL-6
T97545 1080-1084 UBERON:0002048;GO:0030324 denotes lung
T69652 1085-1091 GO:0006281 denotes repair
T14865 1102-1107 NCBITaxon:10239 denotes viral
T99385 1142-1146 PR:000001393 denotes IL-6
T38399 1147-1156 CHEBI:35222;CHEBI:35222 denotes inhibitor
T45524 1157-1162 CHEBI:23888;CHEBI:23888 denotes drugs
T52740 1210-1218 SP_7 denotes COVID-19
T66483 1237-1243 UBERON:0002113 denotes kidney
T65017 1248-1253 UBERON:0002107 denotes liver
T45829 1288-1292 PR:000001393 denotes IL-6
T679 1293-1302 CHEBI:35222;CHEBI:35222 denotes inhibitor

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T8 590-598 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T9 645-656 Body_part denotes solid organ http://purl.org/sig/ont/fma/fma55670
T10 726-730 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T11 884-888 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T12 1032-1045 Body_part denotes interleukin-6 http://purl.org/sig/ont/fma/fma264829
T13 1080-1084 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T14 1237-1243 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T15 1248-1253 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T16 1316-1324 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T6 651-656 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T7 726-730 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T8 1080-1084 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T9 1237-1243 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T10 1248-1253 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T13 95-103 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 299-307 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 372-380 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 384-419 Disease denotes Acute Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T17 390-419 Disease denotes Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T18 421-425 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T19 519-523 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T20 563-575 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T21 608-616 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 750-758 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T23 1210-1218 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T16 50-62 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T17 63-66 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T18 252-255 http://purl.obolibrary.org/obo/CL_0000990 denotes CDC
T19 324-329 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2]. A
T20 546-547 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 588-589 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T22 651-656 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T23 685-686 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 726-730 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T25 884-888 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T26 1032-1045 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin-6
T27 1080-1084 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T28 1080-1084 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T29 1200-1201 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 1222-1223 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T31 1237-1243 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T32 1237-1243 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T33 1237-1243 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T34 1248-1253 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T35 1248-1253 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T36 1314-1315 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T7 1047-1049 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T9 1142-1144 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T11 1147-1156 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T12 1157-1162 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T13 1288-1290 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T15 1293-1302 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
61 1032-1045 Gene denotes interleukin-6 Gene:3569
62 1047-1051 Gene denotes IL-6 Gene:3569
63 1142-1146 Gene denotes IL-6 Gene:3569
64 1288-1292 Gene denotes IL-6 Gene:3569
65 175-192 Species denotes novel Coronavirus Tax:2697049
66 617-625 Species denotes patients Tax:9606
67 709-717 Species denotes patients Tax:9606
68 1224-1231 Species denotes patient Tax:9606
69 95-103 Disease denotes COVID-19 MESH:C000657245
70 126-132 Disease denotes deaths MESH:D003643
71 299-307 Disease denotes COVID-19 MESH:C000657245
72 316-322 Disease denotes deaths MESH:D003643
73 372-380 Disease denotes COVID-19 MESH:C000657245
74 390-419 Disease denotes Respiratory Distress Syndrome MESH:D012128
75 421-425 Disease denotes ARDS MESH:D012128
76 519-523 Disease denotes ARDS MESH:D012128
77 557-575 Disease denotes hyper-inflammation MESH:D007249
78 608-616 Disease denotes COVID-19 MESH:C000657245
79 750-758 Disease denotes COVID-19 MESH:C000657245
80 966-971 Disease denotes COVID MESH:C000657245
81 1210-1218 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T5 390-410 Phenotype denotes Respiratory Distress http://purl.obolibrary.org/obo/HP_0002098
T6 590-604 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T7 1316-1330 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 563-575 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T2 884-906 http://purl.obolibrary.org/obo/GO_0002456 denotes cell-mediated immunity
T3 884-906 http://purl.obolibrary.org/obo/GO_0002449 denotes cell-mediated immunity
T4 926-940 http://purl.obolibrary.org/obo/GO_0019076 denotes viral shedding

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T8 0-12 Sentence denotes Introduction
T9 13-197 Sentence denotes As of May 14, 2020, the World Health Organization has reported 4,248,386 cases of COVID-19 with 294,046 reported deaths secondary to complications related to the novel Coronavirus [1].
T10 198-327 Sentence denotes In the United States, the Center for Disease Control (CDC) reported 1,364,061 total cases and 82,246 COVID-19 related deaths [2].
T11 328-487 Sentence denotes A common complication reported secondary to COVID-19 is Acute Respiratory Distress Syndrome (ARDS) requiring endotracheal intubation and ventilator management.
T12 488-630 Sentence denotes Experts currently believe that ARDS possibly results from a state of hyper-inflammation mediated by a cytokine storm in COVID-19 patients [3].
T13 631-827 Sentence denotes Recipients of solid organ transplants are included in a special population of patients who may face increased risks of COVID-19 related complications given their use of chronic immunosuppressants.
T14 828-998 Sentence denotes Immunosuppression in this population can further reduce cell-mediated immunity, which may prolong viral shedding and increase the risk of COVID related complications [3].
T15 999-1189 Sentence denotes As reported by McGonagle et al., interleukin-6 (IL-6) plays an important role in lung repair following viral insults and the administration of IL-6 inhibitor drugs may be time-sensitive [3].
T16 1190-1347 Sentence denotes We report a case of COVID-19 in a patient with kidney and liver transplant and discuss the use of IL-6 inhibitor to prevent a cytokine storm in this setting.