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PMC:7318948 / 1069-18503 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T23 95-103 SP_7 denotes COVID-19
T24 126-132 GO:0016265 denotes deaths
T25 181-192 NCBITaxon:11118 denotes Coronavirus
T26 299-307 SP_7 denotes COVID-19
T27 316-322 GO:0016265 denotes deaths
T28 372-380 SP_7 denotes COVID-19
T29 437-449 UBERON:0001852 denotes endotracheal
T30 608-616 SP_7 denotes COVID-19
T31 651-656 UBERON:0000062 denotes organ
T32 750-758 SP_7 denotes COVID-19
T33 808-826 CHEBI:35705;CHEBI:35705 denotes immunosuppressants
T34 926-931 NCBITaxon:10239 denotes viral
T35 1032-1045 PR:000001393 denotes interleukin-6
T36 1047-1051 PR:000001393 denotes IL-6
T37 1080-1084 UBERON:0002048;GO:0030324 denotes lung
T38 1085-1091 GO:0006281 denotes repair
T39 1102-1107 NCBITaxon:10239 denotes viral
T40 1142-1146 PR:000001393 denotes IL-6
T41 1147-1156 CHEBI:35222;CHEBI:35222 denotes inhibitor
T42 1157-1162 CHEBI:23888;CHEBI:23888 denotes drugs
T43 1210-1218 SP_7 denotes COVID-19
T44 1237-1243 UBERON:0002113 denotes kidney
T45 1248-1253 UBERON:0002107 denotes liver
T46 1288-1292 PR:000001393 denotes IL-6
T47 1293-1302 CHEBI:35222;CHEBI:35222 denotes inhibitor
T48 1395-1401 UBERON:0002113 denotes kidney
T49 1406-1411 UBERON:0002107 denotes liver
T50 1534-1540 UBERON:0002048 denotes breath
T51 1697-1702 UBERON:0001443 denotes chest
T52 1796-1804 SP_7 denotes COVID-19
T53 1917-1922 CL:0000738 denotes white
T54 1923-1928 CL:0000738;UBERON:0000178 denotes blood
T55 1929-1933 CL:0000738 denotes cell
T56 1979-1989 CL:0000542 denotes lymphocyte
T57 2016-2021 UBERON:0002107 denotes liver
T58 2038-2053 NCBITaxon:10358 denotes Cytomegalovirus
T59 2058-2068 NCBITaxon:517 denotes Bordetella
T60 2111-2128 CHEBI:35705;CHEBI:35705 denotes immunosuppressant
T61 2150-2167 CHEBI:168396;CHEBI:168396 denotes mycophenolic acid
T62 2190-2200 CHEBI:8382;CHEBI:8382 denotes prednisone
T63 2315-2319 UBERON:0000165 denotes oral
T64 2320-2330 CHEBI:8382;CHEBI:8382 denotes prednisone
T65 2334-2352 CHEBI:12071;CHEBI:12071;DG_36 denotes methylprednisolone
T66 2435-2443 CHEBI:478164;CHEBI:478164 denotes cefepime
T67 2495-2513 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T68 2727-2732 UBERON:0001443 denotes chest
T69 2758-2762 UBERON:0002171 denotes lobe
T70 2782-2788 UBERON:0000915 denotes Thorax
T71 2844-2848 UBERON:3010752 denotes lobe
T72 2908-2913 NCBITaxon:10239 denotes viral
T73 3089-3097 SP_7 denotes COVID-19
T74 3098-3103 UBERON:0001977 denotes serum
T75 3104-3114 GO:0042571 denotes antibodies
T76 3155-3163 SP_7 denotes COVID-19
T77 3164-3178 GO:0071743 denotes IgG antibodies
T78 3214-3225 DG_35 denotes tocilizumab
T79 3300-3306 UBERON:0002048 denotes breath
T80 3376-3381 UBERON:0000004 denotes nasal
T81 3482-3487 UBERON:0001443 denotes chest
T82 3597-3614 CHEBI:168396;CHEBI:168396 denotes Mycophenolic acid
T83 3619-3629 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T88 5125-5136 DG_35 denotes tocilizumab
T89 5279-5284 UBERON:0001443 denotes chest
T90 5295-5300 UBERON:0002107 denotes liver
T91 5317-5322 UBERON:0000178 denotes blood
T92 5323-5327 CHEBI:16199;CHEBI:16199 denotes urea
T93 5348-5358 CHEBI:16737;CHEBI:16737 denotes creatinine
T94 5485-5494 NCBITaxon:2 denotes bacterial
T95 5566-5572 UBERON:0001969 denotes plasma
T96 5791-5801 SP_7 denotes SARS-CoV-2
T97 5833-5844 NCBITaxon:11118 denotes coronavirus
T98 5983-5991 SP_7 denotes COVID-19
T99 6014-6020 GO:0016265 denotes deaths
T100 6069-6080 NCBITaxon:11118 denotes Coronavirus
T101 6282-6287 UBERON:0000062 denotes organ
T102 6393-6410 CHEBI:35705;CHEBI:35705 denotes immunosuppressant
T103 6567-6575 SP_7 denotes Covid-19
T104 6858-6863 UBERON:0002048 denotes cough
T105 6886-6892 UBERON:0007311 denotes sputum
T106 6969-6978 UBERON:0000916 denotes abdominal
T107 7034-7042 SP_7 denotes COVID-19
T108 7120-7125 UBERON:0000062 denotes organ
T156 7192-7200 SP_7 denotes COVID 19
T157 7231-7244 CHEBI:16625;CHEBI:16625 denotes Mycophenolate
T158 7260-7265 CL:0000738 denotes White
T159 7266-7271 CL:0000738;UBERON:0000178 denotes blood
T160 7272-7276 CL:0000738 denotes cell
T161 7290-7308 PR:000005897 denotes C-reactive protein
T162 7316-7323 CHEBI:24996;CHEBI:24996 denotes lactate
T163 10656-10664 SP_7 denotes COVID-19
T164 10713-10721 SP_7 denotes COVID-19
T165 10736-10747 UBERON:0001004 denotes respiratory
T166 10828-10835 GO:0006952 denotes defense
T167 10847-10852 NCBITaxon:10239 denotes virus
T168 10948-10955 GO:0006952 denotes defense
T169 11040-11046 UBERON:0000479 denotes tissue
T170 11107-11118 CL:0000232 denotes erythrocyte
T171 11145-11163 PR:000005897 denotes C-reactive protein
T172 11165-11168 PR:000005897 denotes CRP
T173 11171-11176 UBERON:0001977 denotes serum
T174 11273-11281 SP_7 denotes COVID-19
T175 11296-11309 PR:000001393 denotes Interleukin-6
T176 11311-11315 PR:000001393 denotes IL-6
T177 11424-11428 PR:000001393 denotes IL-6
T178 11611-11615 PR:000001393 denotes IL-6
T179 11631-11636 PR:000001394 denotes IL-6R
T180 11651-11658 GO:0032991 denotes complex
T181 11668-11672 PR:000001394 denotes IL6R
T182 11673-11680 GO:0032991 denotes complex
T183 11695-11703 GO:0016020 denotes membrane
T184 11737-11750 GO:0005622;GO:0035556 denotes intracellular
T185 11751-11763 GO:0009293 denotes transduction
T186 11820-11824 PR:000001393 denotes IL-6
T187 11836-11842 PR:000001798 denotes sIL-6R
T188 11857-11864 GO:0032991 denotes complex
T189 11874-11879 PR:000001798 denotes sIL6R
T190 11880-11887 GO:0032991 denotes complex
T191 11902-11910 GO:0016020 denotes membrane
T192 11939-11952 GO:0005622;GO:0035556 denotes intracellular
T193 11953-11972 GO:0035556 denotes signal transduction
T194 12035-12042 GO:0032991 denotes complex
T195 12048-12054 PR:000001798 denotes sIL-6R
T196 12066-12072 PR:000001798 denotes sIL-6R
T197 12089-12097 GO:0016020 denotes membrane
T198 12139-12142 PR:000002110 denotes ATK
T199 12252-12256 PR:000001393 denotes IL-6
T200 12391-12395 PR:000001393 denotes IL-6
T201 12406-12414 SP_7 denotes COVID-19
T202 12496-12500 PR:000001393 denotes IL-6
T203 12624-12628 PR:000001393 denotes IL-6
T204 12639-12647 SP_7 denotes COVID-19
T205 12668-12673 UBERON:0000062 denotes organ
T206 12785-12796 DG_35 denotes tocilizumab
T207 12811-12819 GO:0042571 denotes antibody
T208 12838-12842 PR:000001393 denotes IL-6
T209 12905-12910 PR:000001394 denotes IL-6R
T210 12912-12923 DG_35 denotes tocilizumab
T211 13157-13165 SP_7 denotes COVID-19
T212 13452-13463 DG_35 denotes tocilizumab
T213 13554-13562 SP_7 denotes Covid-19
T214 13587-13596 DG_23 denotes lopinavir
T215 13598-13616 DG_36;CHEBI:30860;CHEBI:30860 denotes methylprednisolone
T216 13884-13888 PR:000001393 denotes IL-6
T217 13899-13912 CHEBI:6909;CHEBI:6909 denotes metronidazole
T218 13964-13977 CHEBI:6909;CHEBI:6909 denotes metronidazole
T219 13988-13993 UBERON:0001977 denotes serum
T220 13994-13998 PR:000001393 denotes IL-6
T221 14032-14049 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T222 14090-14098 SP_7 denotes COVID-19
T223 14153-14159 UBERON:0002405;GO:0006955 denotes immune
T224 14160-14168 GO:0006955 denotes response
T225 14181-14186 NCBITaxon:10239 denotes viral
T226 14274-14291 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T227 14397-14402 NCBITaxon:10239 denotes viral
T228 14567-14571 SP_10 denotes SARS
T229 14601-14606 NCBITaxon:10239 denotes viral
T230 14806-14811 UBERON:0002107 denotes liver
T231 14858-14866 SP_7 denotes COVID-19
T232 14964-14974 CL:0000542 denotes lymphocyte
T233 15012-15016 PR:000001393 denotes IL-6
T234 15086-15094 SP_7 denotes COVID-19
T235 15151-15155 PR:000001393 denotes IL-6
T236 15185-15193 SP_7 denotes COVID-19
T237 15287-15291 PR:000001393 denotes IL-6
T238 15339-15344 NCBITaxon:10239 denotes viral
T239 15440-15445 NCBITaxon:10239 denotes viral
T240 15531-15535 PR:000001393 denotes IL-6
T241 15569-15579 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T242 15611-15628 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T243 15704-15721 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T244 15807-15815 SP_7 denotes COVID-19
T245 15849-15854 NCBITaxon:10239 denotes virus
T246 15855-15859 GO:0018995 denotes host
T247 15923-15931 SP_7 denotes COVID-19
T248 16116-16127 UBERON:0001004 denotes respiratory
T249 16171-16175 PR:000001393 denotes IL-6
T250 16422-16433 DG_35 denotes tocilizumab
T251 16621-16629 SP_7 denotes COVID-19
T252 16667-16672 UBERON:0000062 denotes organ
T253 16697-16701 PR:000001393 denotes IL-6
T254 16702-16711 CHEBI:35222;CHEBI:35222 denotes inhibitor
T255 16811-16822 DG_35 denotes tocilizumab
T256 16899-16910 UBERON:0001004 denotes respiratory
T257 17076-17087 UBERON:0001004 denotes respiratory
T258 17113-17127 GO:0007596 denotes Thromboembolic
T259 17168-17179 UBERON:0001004 denotes respiratory
T260 17284-17292 SP_7 denotes COVID-19
T261 17313-17318 UBERON:0000062 denotes organ
T262 17402-17410 SP_7 denotes COVID-19
T26793 95-103 SP_7 denotes COVID-19
T17320 126-132 GO:0016265 denotes deaths
T29874 181-192 NCBITaxon:11118 denotes Coronavirus
T65188 299-307 SP_7 denotes COVID-19
T18243 316-322 GO:0016265 denotes deaths
T75932 372-380 SP_7 denotes COVID-19
T83510 437-449 UBERON:0001852 denotes endotracheal
T83503 608-616 SP_7 denotes COVID-19
T80946 651-656 UBERON:0000062 denotes organ
T2797 750-758 SP_7 denotes COVID-19
T18817 808-826 CHEBI:35705;CHEBI:35705 denotes immunosuppressants
T49695 926-931 NCBITaxon:10239 denotes viral
T30614 1032-1045 PR:000001393 denotes interleukin-6
T71673 1047-1051 PR:000001393 denotes IL-6
T97545 1080-1084 UBERON:0002048;GO:0030324 denotes lung
T69652 1085-1091 GO:0006281 denotes repair
T14865 1102-1107 NCBITaxon:10239 denotes viral
T99385 1142-1146 PR:000001393 denotes IL-6
T38399 1147-1156 CHEBI:35222;CHEBI:35222 denotes inhibitor
T45524 1157-1162 CHEBI:23888;CHEBI:23888 denotes drugs
T52740 1210-1218 SP_7 denotes COVID-19
T66483 1237-1243 UBERON:0002113 denotes kidney
T65017 1248-1253 UBERON:0002107 denotes liver
T45829 1288-1292 PR:000001393 denotes IL-6
T679 1293-1302 CHEBI:35222;CHEBI:35222 denotes inhibitor
T32180 1395-1401 UBERON:0002113 denotes kidney
T73190 1406-1411 UBERON:0002107 denotes liver
T53403 1534-1540 UBERON:0002048 denotes breath
T23752 1697-1702 UBERON:0001443 denotes chest
T80248 1796-1804 SP_7 denotes COVID-19
T51573 1917-1922 CL:0000738 denotes white
T84453 1923-1928 CL:0000738;UBERON:0000178 denotes blood
T13289 1929-1933 CL:0000738 denotes cell
T23080 1979-1989 CL:0000542 denotes lymphocyte
T19421 2016-2021 UBERON:0002107 denotes liver
T296 2038-2053 NCBITaxon:10358 denotes Cytomegalovirus
T32770 2058-2068 NCBITaxon:517 denotes Bordetella
T82516 2111-2128 CHEBI:35705;CHEBI:35705 denotes immunosuppressant
T81314 2150-2167 CHEBI:168396;CHEBI:168396 denotes mycophenolic acid
T93225 2190-2200 CHEBI:8382;CHEBI:8382 denotes prednisone
T44728 2315-2319 UBERON:0000165 denotes oral
T75404 2320-2330 CHEBI:8382;CHEBI:8382 denotes prednisone
T13426 2334-2352 CHEBI:12071;CHEBI:12071;DG_36 denotes methylprednisolone
T22170 2435-2443 CHEBI:478164;CHEBI:478164 denotes cefepime
T46657 2495-2513 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T72158 2727-2732 UBERON:0001443 denotes chest
T49026 2758-2762 UBERON:0002171 denotes lobe
T449 2782-2788 UBERON:0000915 denotes Thorax
T62838 2844-2848 UBERON:3010752 denotes lobe
T39963 2908-2913 NCBITaxon:10239 denotes viral
T8877 3089-3097 SP_7 denotes COVID-19
T70913 3098-3103 UBERON:0001977 denotes serum
T31701 3104-3114 GO:0042571 denotes antibodies
T42057 3155-3163 SP_7 denotes COVID-19
T96333 3164-3178 GO:0071743 denotes IgG antibodies
T15351 3214-3225 DG_35 denotes tocilizumab
T75046 3300-3306 UBERON:0002048 denotes breath
T55692 3376-3381 UBERON:0000004 denotes nasal
T63107 3482-3487 UBERON:0001443 denotes chest
T83619 3597-3614 CHEBI:168396;CHEBI:168396 denotes Mycophenolic acid
T25649 3619-3629 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T84 4283-4293 CHEBI:16737;CHEBI:16737 denotes Creatinine
T61793 5125-5136 DG_35 denotes tocilizumab
T10250 5279-5284 UBERON:0001443 denotes chest
T18769 5295-5300 UBERON:0002107 denotes liver
T14105 5317-5322 UBERON:0000178 denotes blood
T47981 5323-5327 CHEBI:16199;CHEBI:16199 denotes urea
T4500 5348-5358 CHEBI:16737;CHEBI:16737 denotes creatinine
T9642 5485-5494 NCBITaxon:2 denotes bacterial
T21028 5566-5572 UBERON:0001969 denotes plasma
T87433 5791-5801 SP_7 denotes SARS-CoV-2
T40787 5833-5844 NCBITaxon:11118 denotes coronavirus
T17140 5983-5991 SP_7 denotes COVID-19
T58361 6014-6020 GO:0016265 denotes deaths
T98629 6069-6080 NCBITaxon:11118 denotes Coronavirus
T11144 6282-6287 UBERON:0000062 denotes organ
T47847 6393-6410 CHEBI:35705;CHEBI:35705 denotes immunosuppressant
T2205 6567-6575 SP_7 denotes Covid-19
T91774 6858-6863 UBERON:0002048 denotes cough
T94519 6886-6892 UBERON:0007311 denotes sputum
T86620 6969-6978 UBERON:0000916 denotes abdominal
T59678 7034-7042 SP_7 denotes COVID-19
T92391 7120-7125 UBERON:0000062 denotes organ
T109 7192-7200 SP_7 denotes COVID 19
T110 7231-7244 CHEBI:16625;CHEBI:16625 denotes Mycophenolate
T111 7260-7265 CL:0000738 denotes White
T112 7266-7271 CL:0000738;UBERON:0000178 denotes blood
T113 7272-7276 CL:0000738 denotes cell
T114 7290-7308 PR:000005897 denotes C-reactive protein
T115 7316-7323 CHEBI:24996;CHEBI:24996 denotes lactate
T116 7354-7359 UBERON:0000062 denotes Organ
T117 7492-7503 CL:0000542 denotes Lymphocytes
T118 7657-7678 CHEBI:27641;CHEBI:27641 denotes cefoperazonesulbactam
T119 7825-7835 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T120 7925-7937 CHEBI:63611;CHEBI:63611 denotes moxifloxacin
T121 7951-7956 SP_6;NCBITaxon:9606 denotes human
T122 7957-7973 PR:000024938 denotes interferon alpha
T123 7975-7993 DG_36 denotes methylprednisolone
T124 7995-8000 SP_6;NCBITaxon:9606 denotes human
T125 8194-8201 DG_49 denotes arbidol
T126 8202-8217 CHEBI:24261;CHEBI:24261 denotes Glucocorticoids
T127 8363-8370 DG_49 denotes arbidol
T128 8371-8379 CHEBI:478164;CHEBI:478164 denotes cefepime
T129 8389-8404 CHEBI:24261;CHEBI:24261 denotes Glucocorticoids
T130 8565-8572 CHEBI:57472;CHEBI:57472;DG_49 denotes arbidol
T131 8573-8585 CHEBI:27641;CHEBI:27641 denotes cefepimeIVIG
T132 8801-8808 CHEBI:57472;CHEBI:57472;DG_49 denotes arbidol
T133 9005-9012 CHEBI:57472;CHEBI:57472;DG_49 denotes arbidol
T134 9013-9028 CHEBI:24261;CHEBI:24261 denotes Glucocorticoids
T135 9143-9153 DG_49 denotes Umifenovir
T136 9155-9164 DG_23 denotes Lopinavir
T137 9165-9174 DG_30 denotes ritonavir
T138 9175-9179 CHEBI:42098;CHEBI:42098 denotes IVIG
T139 9180-9192 CHEBI:27641;CHEBI:27641 denotes Cefoperazone
T140 9380-9389 DG_30 denotes ritonavir
T141 9391-9400 DG_29 denotes ribavirin
T142 9402-9418 PR:000008915 denotes interferon alpha
T143 9423-9441 DG_36 denotes methylprednisolone
T144 9606-9620 CHEBI:29007;CHEBI:29007 denotes ceftriaxone 26
T145 9914-9922 CHEBI:23243;CHEBI:23243 denotes opinavir
T146 9923-9932 DG_30 denotes ritonavir
T147 9934-9945 CHEBI:29007;CHEBI:29007 denotes ceftriaxone
T148 9947-9957 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T149 10017-10021 PR:000001395 denotes IL-8
T150 10028-10052 CL:0000775 denotes neutrophil normal 67 Not
T151 10255-10260 GO:0016265 denotes death
T152 10274-10279 UBERON:0000062 denotes organ
T153 10359-10371 CHEBI:25435;CHEBI:25435 denotes Moxifloxacin
T154 10372-10390 DG_36 denotes Methylprednisolone
T155 10422-10446 CHEBI:35705;CHEBI:35705 denotes immunosuppressive agents
T74105 10656-10664 SP_7 denotes COVID-19
T48382 10713-10721 SP_7 denotes COVID-19
T53841 10736-10747 UBERON:0001004 denotes respiratory
T69954 10828-10835 GO:0006952 denotes defense
T35920 10847-10852 NCBITaxon:10239 denotes virus
T99777 10948-10955 GO:0006952 denotes defense
T93200 11040-11046 UBERON:0000479 denotes tissue
T89188 11107-11118 CL:0000232 denotes erythrocyte
T89814 11145-11163 PR:000005897 denotes C-reactive protein
T54489 11165-11168 PR:000005897 denotes CRP
T55308 11171-11176 UBERON:0001977 denotes serum
T91455 11273-11281 SP_7 denotes COVID-19
T47700 11296-11309 PR:000001393 denotes Interleukin-6
T50297 11311-11315 PR:000001393 denotes IL-6
T79041 11424-11428 PR:000001393 denotes IL-6
T64701 11611-11615 PR:000001393 denotes IL-6
T65264 11631-11636 PR:000001394 denotes IL-6R
T24982 11651-11658 GO:0032991 denotes complex
T68031 11668-11672 PR:000001394 denotes IL6R
T46746 11673-11680 GO:0032991 denotes complex
T40582 11695-11703 GO:0016020 denotes membrane
T59216 11737-11750 GO:0005622;GO:0035556 denotes intracellular
T30937 11751-11763 GO:0009293 denotes transduction
T71806 11820-11824 PR:000001393 denotes IL-6
T48498 11836-11842 PR:000001798 denotes sIL-6R
T61458 11857-11864 GO:0032991 denotes complex
T21126 11874-11879 PR:000001798 denotes sIL6R
T30624 11880-11887 GO:0032991 denotes complex
T32439 11902-11910 GO:0016020 denotes membrane
T86675 11939-11952 GO:0005622;GO:0035556 denotes intracellular
T15304 11953-11972 GO:0035556 denotes signal transduction
T43481 12035-12042 GO:0032991 denotes complex
T75201 12048-12054 PR:000001798 denotes sIL-6R
T18390 12066-12072 PR:000001798 denotes sIL-6R
T30397 12089-12097 GO:0016020 denotes membrane
T25251 12139-12142 PR:000002110 denotes ATK
T74114 12252-12256 PR:000001393 denotes IL-6
T60722 12391-12395 PR:000001393 denotes IL-6
T56397 12406-12414 SP_7 denotes COVID-19
T49424 12496-12500 PR:000001393 denotes IL-6
T23213 12624-12628 PR:000001393 denotes IL-6
T7988 12639-12647 SP_7 denotes COVID-19
T61629 12668-12673 UBERON:0000062 denotes organ
T16211 12785-12796 DG_35 denotes tocilizumab
T77835 12811-12819 GO:0042571 denotes antibody
T47264 12838-12842 PR:000001393 denotes IL-6
T81296 12905-12910 PR:000001394 denotes IL-6R
T19612 12912-12923 DG_35 denotes tocilizumab
T40951 13157-13165 SP_7 denotes COVID-19
T81802 13452-13463 DG_35 denotes tocilizumab
T59755 13554-13562 SP_7 denotes Covid-19
T94468 13587-13596 DG_23 denotes lopinavir
T18366 13598-13616 DG_36;CHEBI:30860;CHEBI:30860 denotes methylprednisolone
T58059 13884-13888 PR:000001393 denotes IL-6
T58922 13899-13912 CHEBI:6909;CHEBI:6909 denotes metronidazole
T27613 13964-13977 CHEBI:6909;CHEBI:6909 denotes metronidazole
T61924 13988-13993 UBERON:0001977 denotes serum
T20855 13994-13998 PR:000001393 denotes IL-6
T4621 14032-14049 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T9248 14090-14098 SP_7 denotes COVID-19
T85163 14153-14159 UBERON:0002405;GO:0006955 denotes immune
T41905 14160-14168 GO:0006955 denotes response
T33200 14181-14186 NCBITaxon:10239 denotes viral
T45112 14274-14291 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T53815 14397-14402 NCBITaxon:10239 denotes viral
T54517 14567-14571 SP_10 denotes SARS
T90338 14601-14606 NCBITaxon:10239 denotes viral
T14177 14806-14811 UBERON:0002107 denotes liver
T32097 14858-14866 SP_7 denotes COVID-19
T53579 14964-14974 CL:0000542 denotes lymphocyte
T54424 15012-15016 PR:000001393 denotes IL-6
T55605 15086-15094 SP_7 denotes COVID-19
T82799 15151-15155 PR:000001393 denotes IL-6
T96738 15185-15193 SP_7 denotes COVID-19
T48035 15287-15291 PR:000001393 denotes IL-6
T78381 15339-15344 NCBITaxon:10239 denotes viral
T73784 15440-15445 NCBITaxon:10239 denotes viral
T46486 15531-15535 PR:000001393 denotes IL-6
T69420 15569-15579 CHEBI:15891;CHEBI:15891 denotes tacrolimus
T27409 15611-15628 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T63247 15704-15721 CHEBI:35705;CHEBI:35705 denotes immunosuppressive
T56582 15807-15815 SP_7 denotes COVID-19
T43770 15849-15854 NCBITaxon:10239 denotes virus
T95404 15855-15859 GO:0018995 denotes host
T75590 15923-15931 SP_7 denotes COVID-19
T92228 16116-16127 UBERON:0001004 denotes respiratory
T33751 16171-16175 PR:000001393 denotes IL-6
T63305 16422-16433 DG_35 denotes tocilizumab
T53081 16621-16629 SP_7 denotes COVID-19
T40237 16667-16672 UBERON:0000062 denotes organ
T50732 16697-16701 PR:000001393 denotes IL-6
T20616 16702-16711 CHEBI:35222;CHEBI:35222 denotes inhibitor
T9065 16811-16822 DG_35 denotes tocilizumab
T92411 16899-16910 UBERON:0001004 denotes respiratory
T9846 17076-17087 UBERON:0001004 denotes respiratory
T4781 17113-17127 GO:0007596 denotes Thromboembolic
T63580 17168-17179 UBERON:0001004 denotes respiratory
T70599 17284-17292 SP_7 denotes COVID-19
T64011 17313-17318 UBERON:0000062 denotes organ
T48557 17402-17410 SP_7 denotes COVID-19

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T8 590-598 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T9 645-656 Body_part denotes solid organ http://purl.org/sig/ont/fma/fma55670
T10 726-730 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T11 884-888 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T12 1032-1045 Body_part denotes interleukin-6 http://purl.org/sig/ont/fma/fma264829
T13 1080-1084 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T14 1237-1243 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T15 1248-1253 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T16 1316-1324 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T17 1395-1401 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T18 1406-1411 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T19 1697-1702 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T20 1917-1933 Body_part denotes white blood cell http://purl.org/sig/ont/fma/fma62852
T21 1929-1933 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T22 1979-1989 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T23 2016-2021 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T24 2727-2732 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T25 2746-2762 Body_part denotes right lower lobe http://purl.org/sig/ont/fma/fma7337
T26 2782-2788 Body_part denotes Thorax http://purl.org/sig/ont/fma/fma9576
T27 3098-3103 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T28 3164-3167 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T29 3482-3487 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T30 3765-3771 Body_part denotes Thorax http://purl.org/sig/ont/fma/fma9576
T31 3834-3840 Body_part denotes Thorax http://purl.org/sig/ont/fma/fma9576
T32 3903-3909 Body_part denotes Thorax http://purl.org/sig/ont/fma/fma9576
T33 3969-3974 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T34 4234-4245 Body_part denotes Lymphocytes http://purl.org/sig/ont/fma/fma62863
T35 4535-4542 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T36 5279-5284 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T37 5295-5300 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T38 5317-5322 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T39 5566-5572 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T40 6276-6287 Body_part denotes solid organ http://purl.org/sig/ont/fma/fma55670
T41 6886-6892 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T42 7114-7125 Body_part denotes solid organ http://purl.org/sig/ont/fma/fma55670
T43 7260-7276 Body_part denotes White blood cell http://purl.org/sig/ont/fma/fma62852
T44 7272-7276 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T45 7301-7308 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T46 7348-7359 Body_part denotes Solid Organ http://purl.org/sig/ont/fma/fma55670
T47 7354-7359 Body_part denotes Organ http://purl.org/sig/ont/fma/fma67498
T48 7492-7503 Body_part denotes Lymphocytes http://purl.org/sig/ont/fma/fma62863
T49 7607-7612 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T50 7647-7655 Body_part denotes capsules http://purl.org/sig/ont/fma/fma85272
T51 7877-7883 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T52 8074-8085 Body_part denotes Bone marrow http://purl.org/sig/ont/fma/fma9608
T53 8138-8144 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T54 8306-8312 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T55 8507-8513 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T56 8743-8749 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T57 8947-8953 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T58 9106-9111 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T59 9334-9340 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T60 9556-9562 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T61 9689-9695 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T62 9853-9859 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T63 10028-10038 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T64 10092-10098 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T65 10274-10279 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T66 10316-10322 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T67 10924-10928 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T68 11014-11022 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T69 11040-11046 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T70 11107-11118 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T71 11156-11163 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T72 11171-11176 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T73 11187-11201 Body_part denotes interleukins 6 http://purl.org/sig/ont/fma/fma264829
T74 11187-11199 Body_part denotes interleukins http://purl.org/sig/ont/fma/fma86578
T75 11233-11244 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T76 11296-11309 Body_part denotes Interleukin-6 http://purl.org/sig/ont/fma/fma264829
T77 11296-11307 Body_part denotes Interleukin http://purl.org/sig/ont/fma/fma86578
T78 11403-11411 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T79 12520-12528 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T80 12662-12673 Body_part denotes solid organ http://purl.org/sig/ont/fma/fma55670
T81 12811-12819 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T82 13052-13060 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T83 13988-13993 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T84 14341-14349 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T85 14403-14406 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T86 14764-14772 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T87 14806-14811 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T88 14964-14974 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T89 15045-15053 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T90 15655-15663 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T91 15962-15970 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T92 15987-15995 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T93 16246-16254 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T94 16661-16672 Body_part denotes solid organ http://purl.org/sig/ont/fma/fma55670
T95 16924-16932 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T96 17307-17318 Body_part denotes solid organ http://purl.org/sig/ont/fma/fma55670

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T6 651-656 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T7 726-730 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T8 1080-1084 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T9 1237-1243 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T10 1248-1253 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T11 1395-1401 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T12 1406-1411 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T13 1697-1702 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T14 1923-1928 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T15 2016-2021 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T16 2727-2732 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T17 2758-2762 Body_part denotes lobe http://purl.obolibrary.org/obo/UBERON_3010752
T18 2844-2848 Body_part denotes lobe http://purl.obolibrary.org/obo/UBERON_3010752
T19 3098-3103 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T20 3482-3487 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T21 3969-3974 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T22 5279-5284 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T23 5285-5289 Body_part denotes tube http://purl.obolibrary.org/obo/UBERON_0000025
T24 5295-5300 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T25 5317-5322 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T26 6282-6287 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T27 6886-6892 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T28 7120-7125 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T29 7266-7271 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T30 7354-7359 Body_part denotes Organ http://purl.obolibrary.org/obo/UBERON_0000062
T31 7607-7612 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T32 7877-7883 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T33 8074-8085 Body_part denotes Bone marrow http://purl.obolibrary.org/obo/UBERON_0002371
T34 8138-8144 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T35 8306-8312 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T36 8507-8513 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T37 8743-8749 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T38 8947-8953 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T39 9106-9111 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T40 9334-9340 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T41 9556-9562 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T42 9689-9695 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T43 9853-9859 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T44 10092-10098 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T45 10274-10279 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T46 10316-10322 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T47 11040-11046 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T48 11171-11176 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T49 12668-12673 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T50 13988-13993 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T51 14806-14811 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T52 16667-16672 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T53 17313-17318 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T13 95-103 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 299-307 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 372-380 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 384-419 Disease denotes Acute Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T17 390-419 Disease denotes Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T18 421-425 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T19 519-523 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T20 563-575 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T21 608-616 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 750-758 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T23 1210-1218 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 1782-1791 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T25 1796-1804 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T26 1901-1903 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T27 2423-2425 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T28 2622-2624 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T29 2914-2925 Disease denotes pneumonitis http://purl.obolibrary.org/obo/MONDO_0043905
T30 3089-3097 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 3155-3163 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T32 3190-3192 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T33 3549-3551 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T34 4793-4802 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T35 4861-4863 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T36 5096-5098 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T37 5224-5226 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T38 5251-5263 Disease denotes pneumothorax http://purl.obolibrary.org/obo/MONDO_0002076
T39 5397-5399 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T40 5485-5504 Disease denotes bacterial infection http://purl.obolibrary.org/obo/MONDO_0005113
T41 5495-5504 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T42 5680-5692 Disease denotes pneumothorax http://purl.obolibrary.org/obo/MONDO_0002076
T43 5706-5708 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T44 5768-5787 Disease denotes Respiratory Disease http://purl.obolibrary.org/obo/MONDO_0005087
T45 5791-5799 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T46 5815-5825 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T47 5983-5991 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 7034-7042 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 7192-7200 Disease denotes COVID 19 http://purl.obolibrary.org/obo/MONDO_0100096
T50 7225-7228 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T51 7901-7904 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T52 8166-8169 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T53 8334-8337 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T54 8535-8538 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T55 8771-8774 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T56 8975-8978 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T57 9029-9032 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T58 9253-9264 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T59 9354-9357 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T60 9443-9446 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T61 9575-9578 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T62 9590-9593 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T63 9713-9716 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T64 10099-10102 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T65 10268-10287 Disease denotes multi-organ failure http://purl.obolibrary.org/obo/MONDO_0043726
T66 10334-10337 Disease denotes MMF http://purl.obolibrary.org/obo/MONDO_0018942
T67 10656-10664 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 10713-10721 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 10730-10765 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T70 10736-10765 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T71 10767-10771 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T72 10889-10900 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T73 11273-11281 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T74 12365-12376 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T75 12406-12414 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T76 12639-12647 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T77 13157-13165 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T78 14090-14098 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T79 14552-14556 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T80 14567-14571 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T81 14742-14746 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T82 14858-14866 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T83 15086-15094 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 15185-15193 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 15807-15815 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T86 15923-15931 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T87 16058-16060 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T88 16621-16629 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T89 16899-16918 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T90 17168-17187 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T91 17284-17292 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 17402-17410 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T16 50-62 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T17 63-66 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T18 252-255 http://purl.obolibrary.org/obo/CL_0000990 denotes CDC
T19 324-329 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2]. A
T20 546-547 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 588-589 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T22 651-656 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T23 685-686 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 726-730 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T25 884-888 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T26 1032-1045 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin-6
T27 1080-1084 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T28 1080-1084 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T29 1200-1201 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 1222-1223 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T31 1237-1243 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T32 1237-1243 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T33 1237-1243 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T34 1248-1253 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T35 1248-1253 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T36 1314-1315 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T37 1376-1377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T38 1390-1394 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T39 1390-1394 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T40 1395-1401 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T41 1395-1401 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T42 1395-1401 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T43 1406-1411 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T44 1406-1411 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T45 1648-1649 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T46 1697-1702 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T47 1762-1768 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T48 1908-1909 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T49 1923-1928 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T50 1929-1933 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T51 2016-2021 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T52 2016-2021 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T53 2031-2036 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T54 2251-2252 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T55 2727-2732 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T56 2782-2788 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Thorax
T57 2906-2907 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 3080-3084 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Test
T59 3449-3451 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T60 3482-3487 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T61 3765-3771 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Thorax
T62 3834-3840 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Thorax
T63 3903-3909 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Thorax
T64 3969-3974 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T65 4065-4069 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Test
T66 4080-4082 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T67 4102-4105 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3 4
T68 4158-4160 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T69 4191-4193 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T70 4249-4251 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T71 4294-4298 http://purl.obolibrary.org/obo/UBERON_0003101 denotes Male
T72 4294-4298 http://www.ebi.ac.uk/efo/EFO_0000970 denotes Male
T73 4380-4382 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T74 4389-4391 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T75 4420-4422 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T76 4432-4452 http://purl.obolibrary.org/obo/PR_000023540 denotes Alkaline phosphatase
T77 4497-4500 http://purl.obolibrary.org/obo/CLO_0001196 denotes 225
T78 4581-4583 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T79 4680-4684 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T80 4680-4684 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T81 4969-4970 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T82 5108-5109 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T83 5237-5238 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 5277-5278 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 5279-5284 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T86 5285-5289 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tube
T87 5295-5300 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T88 5295-5300 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T89 5310-5315 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T90 5317-5322 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T91 5317-5322 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T92 5566-5572 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T93 5806-5807 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 5938-5950 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T95 5951-5954 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T96 6112-6115 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T97 6282-6287 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T98 7120-7125 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T99 7266-7271 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T100 7272-7276 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T101 7354-7359 http://purl.obolibrary.org/obo/UBERON_0003103 denotes Organ
T102 7480-7482 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T103 7508-7510 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T104 7551-7554 http://purl.obolibrary.org/obo/CLO_0001196 denotes 225
T105 7607-7612 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T106 7607-7612 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T107 7747-7749 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T108 7877-7883 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T109 7877-7883 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T110 7877-7883 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T111 7951-7956 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T112 7995-8000 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T113 8074-8078 http://purl.obolibrary.org/obo/UBERON_0002481 denotes Bone
T114 8138-8144 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T115 8138-8144 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T116 8138-8144 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T117 8306-8312 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T118 8306-8312 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T119 8306-8312 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T120 8507-8513 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T121 8507-8513 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T122 8507-8513 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T123 8727-8729 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T124 8743-8749 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T125 8743-8749 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T126 8743-8749 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T127 8947-8953 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T128 8947-8953 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T129 8947-8953 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T130 9106-9111 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T131 9106-9111 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T132 9334-9340 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T133 9334-9340 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T134 9334-9340 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T135 9556-9562 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T136 9556-9562 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T137 9556-9562 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T138 9689-9695 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T139 9689-9695 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T140 9689-9695 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T141 9836-9838 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T142 9853-9859 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T143 9853-9859 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T144 9853-9859 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T145 10017-10021 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T146 10092-10098 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T147 10092-10098 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T148 10092-10098 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T149 10274-10279 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T150 10307-10309 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T151 10311-10313 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T152 10316-10322 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T153 10316-10322 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T154 10316-10322 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T155 10507-10509 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T156 10534-10536 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T157 10558-10560 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T158 10593-10595 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T159 10673-10674 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T160 10847-10852 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T161 10929-10938 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T162 10939-10940 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T163 11012-11013 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 11107-11118 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T165 11187-11201 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukins 6
T166 11296-11309 http://purl.obolibrary.org/obo/PR_000001393 denotes Interleukin-6
T167 11320-11321 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 11429-11435 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T169 11491-11497 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T170 11518-11524 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T171 11563-11565 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T172 11582-11588 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T173 11649-11650 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T174 11695-11703 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T175 11765-11767 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T176 11780-11786 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T177 11855-11856 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T178 11902-11910 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T179 11953-11959 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T180 11974-11976 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T181 12002-12008 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T182 12033-12034 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T183 12089-12097 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T184 12166-12175 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T185 12177-12179 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T186 12203-12204 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T187 12215-12217 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T188 12331-12332 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T189 12538-12539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T190 12668-12673 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T191 12701-12702 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 12798-12799 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 12853-12856 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T194 12882-12884 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T195 12965-12974 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T196 12995-12996 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T197 13068-13070 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T198 13183-13184 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 13199-13202 http://purl.obolibrary.org/obo/CLO_0001382 denotes 4−8
T200 13283-13284 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T201 13409-13410 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 13765-13766 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T203 14122-14123 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T204 14434-14435 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 14589-14590 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T206 14613-14615 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T207 14780-14782 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T208 14804-14805 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T209 14806-14811 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T210 14806-14811 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T211 14838-14844 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T212 15292-15298 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T213 15324-15325 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T214 15426-15427 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T215 15849-15854 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T216 15953-15954 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T217 15978-15979 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T218 16100-16101 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T219 16348-16349 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T220 16667-16672 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T221 16830-16831 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T222 16955-16956 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T223 17038-17039 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T224 17158-17159 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T225 17189-17190 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T226 17313-17318 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T7 1047-1049 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T9 1142-1144 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T11 1147-1156 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T12 1157-1162 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T13 1288-1290 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T15 1293-1302 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T16 1390-1394 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T17 1476-1478 Chemical denotes ED http://purl.obolibrary.org/obo/CHEBI_73503
T18 1676-1683 Chemical denotes Celsius http://purl.obolibrary.org/obo/CHEBI_145500
T19 2111-2128 Chemical denotes immunosuppressant http://purl.obolibrary.org/obo/CHEBI_35705
T20 2150-2167 Chemical denotes mycophenolic acid http://purl.obolibrary.org/obo/CHEBI_168396
T21 2163-2167 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T22 2190-2200 Chemical denotes prednisone http://purl.obolibrary.org/obo/CHEBI_8382
T23 2221-2231 Chemical denotes tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049|http://purl.obolibrary.org/obo/CHEBI_61057
T25 2320-2330 Chemical denotes prednisone http://purl.obolibrary.org/obo/CHEBI_8382
T26 2334-2352 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T27 2435-2443 Chemical denotes cefepime http://purl.obolibrary.org/obo/CHEBI_478164
T28 2495-2513 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T29 3214-3225 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T30 3331-3337 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T31 3425-3431 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T32 3610-3614 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T33 3619-3629 Chemical denotes tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049|http://purl.obolibrary.org/obo/CHEBI_61057
T35 4283-4293 Chemical denotes Creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T36 4352-4355 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T37 4535-4542 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T38 4571-4573 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T40 4611-4618 Chemical denotes Prograf http://purl.obolibrary.org/obo/CHEBI_61049|http://purl.obolibrary.org/obo/CHEBI_61057
T42 4620-4630 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T43 4671-4679 Chemical denotes Ferritin http://purl.obolibrary.org/obo/CHEBI_82594
T44 4680-4684 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T45 4998-5004 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T46 5067-5073 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T47 5125-5136 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T48 5323-5327 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T49 5328-5336 Chemical denotes nitrogen http://purl.obolibrary.org/obo/CHEBI_25555
T50 5348-5358 Chemical denotes creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T51 6393-6410 Chemical denotes immunosuppressant http://purl.obolibrary.org/obo/CHEBI_35705
T52 7225-7228 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T53 7231-7244 Chemical denotes Mycophenolate http://purl.obolibrary.org/obo/CHEBI_168396
T54 7301-7308 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T55 7316-7323 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T56 7460-7462 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T58 7613-7623 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T59 7624-7646 Chemical denotes Oseltamivir, phosphate http://purl.obolibrary.org/obo/CHEBI_7799
T60 7624-7635 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T61 7637-7646 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T65 7679-7685 Chemical denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708
T66 7825-7835 Chemical denotes tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049|http://purl.obolibrary.org/obo/CHEBI_61057
T68 7890-7900 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T69 7901-7904 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T70 7905-7916 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T71 7925-7937 Chemical denotes moxifloxacin http://purl.obolibrary.org/obo/CHEBI_63611
T72 7957-7967 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T73 7968-7973 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T74 7975-7993 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T75 8166-8169 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T76 8170-8180 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T77 8181-8192 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T78 8194-8201 Chemical denotes arbidol http://purl.obolibrary.org/obo/CHEBI_134730
T79 8334-8337 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T80 8338-8347 Chemical denotes rapamycin http://purl.obolibrary.org/obo/CHEBI_9168
T81 8348-8359 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T82 8363-8370 Chemical denotes arbidol http://purl.obolibrary.org/obo/CHEBI_134730
T83 8371-8379 Chemical denotes cefepime http://purl.obolibrary.org/obo/CHEBI_478164
T84 8535-8538 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T85 8539-8549 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T86 8550-8561 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T87 8565-8572 Chemical denotes arbidol http://purl.obolibrary.org/obo/CHEBI_134730
T88 8771-8774 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T89 8775-8785 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T90 8786-8797 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T91 8801-8808 Chemical denotes arbidol http://purl.obolibrary.org/obo/CHEBI_134730
T92 8975-8978 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T93 8979-8989 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T94 8990-9001 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T95 9005-9012 Chemical denotes arbidol http://purl.obolibrary.org/obo/CHEBI_134730
T96 9029-9032 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T97 9033-9043 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T98 9112-9122 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T99 9155-9164 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T100 9165-9174 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T101 9180-9192 Chemical denotes Cefoperazone http://purl.obolibrary.org/obo/CHEBI_3493
T102 9194-9199 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T103 9341-9353 Chemical denotes Cyclosporine http://purl.obolibrary.org/obo/CHEBI_4031
T104 9354-9357 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T105 9369-9378 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T106 9380-9389 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T107 9391-9400 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T108 9402-9412 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T109 9413-9418 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T110 9423-9441 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T111 9443-9446 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T112 9575-9578 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T113 9579-9589 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T114 9590-9593 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T115 9595-9605 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T116 9606-9617 Chemical denotes ceftriaxone http://purl.obolibrary.org/obo/CHEBI_29007
T117 9713-9716 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T118 9872-9882 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T119 9923-9932 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T120 9934-9945 Chemical denotes ceftriaxone http://purl.obolibrary.org/obo/CHEBI_29007
T121 9947-9957 Chemical denotes tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049|http://purl.obolibrary.org/obo/CHEBI_61057
T123 10017-10019 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T125 10099-10102 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T126 10323-10333 Chemical denotes Tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049
T127 10334-10337 Chemical denotes MMF http://purl.obolibrary.org/obo/CHEBI_8764
T128 10359-10371 Chemical denotes Moxifloxacin http://purl.obolibrary.org/obo/CHEBI_63611
T129 10392-10400 Chemical denotes Biapenem http://purl.obolibrary.org/obo/CHEBI_3089
T130 10402-10412 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T131 10422-10446 Chemical denotes immunosuppressive agents http://purl.obolibrary.org/obo/CHEBI_35705
T132 10818-10827 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T133 10861-10871 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T134 11156-11163 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T135 11187-11199 Chemical denotes interleukins http://purl.obolibrary.org/obo/CHEBI_52998
T136 11311-11313 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T138 11424-11426 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T140 11611-11613 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T142 11631-11633 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T144 11820-11822 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T146 12126-12129 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T147 12252-12254 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T149 12391-12393 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T151 12496-12498 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T153 12624-12626 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T155 12785-12796 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T156 12838-12840 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T158 12905-12907 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T160 12912-12923 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T161 13452-13463 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T162 13587-13596 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T163 13598-13616 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T164 13647-13653 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T165 13884-13886 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T167 13899-13912 Chemical denotes metronidazole http://purl.obolibrary.org/obo/CHEBI_6909
T168 13964-13977 Chemical denotes metronidazole http://purl.obolibrary.org/obo/CHEBI_6909
T169 13994-13996 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T171 14657-14666 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T172 15012-15014 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T174 15151-15153 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T176 15287-15289 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T178 15531-15533 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T180 15569-15579 Chemical denotes tacrolimus http://purl.obolibrary.org/obo/CHEBI_61049|http://purl.obolibrary.org/obo/CHEBI_61057
T182 16171-16173 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T184 16422-16433 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T185 16697-16699 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T187 16702-16711 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T188 16811-16822 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
61 1032-1045 Gene denotes interleukin-6 Gene:3569
62 1047-1051 Gene denotes IL-6 Gene:3569
63 1142-1146 Gene denotes IL-6 Gene:3569
64 1288-1292 Gene denotes IL-6 Gene:3569
65 175-192 Species denotes novel Coronavirus Tax:2697049
66 617-625 Species denotes patients Tax:9606
67 709-717 Species denotes patients Tax:9606
68 1224-1231 Species denotes patient Tax:9606
69 95-103 Disease denotes COVID-19 MESH:C000657245
70 126-132 Disease denotes deaths MESH:D003643
71 299-307 Disease denotes COVID-19 MESH:C000657245
72 316-322 Disease denotes deaths MESH:D003643
73 372-380 Disease denotes COVID-19 MESH:C000657245
74 390-419 Disease denotes Respiratory Distress Syndrome MESH:D012128
75 421-425 Disease denotes ARDS MESH:D012128
76 519-523 Disease denotes ARDS MESH:D012128
77 557-575 Disease denotes hyper-inflammation MESH:D007249
78 608-616 Disease denotes COVID-19 MESH:C000657245
79 750-758 Disease denotes COVID-19 MESH:C000657245
80 966-971 Disease denotes COVID MESH:C000657245
81 1210-1218 Disease denotes COVID-19 MESH:C000657245
92 1365-1372 Species denotes patient Tax:9606
93 2150-2167 Chemical denotes mycophenolic acid MESH:D009173
94 2190-2200 Chemical denotes prednisone MESH:D011241
95 2221-2231 Chemical denotes tacrolimus MESH:D016559
96 1390-1401 Disease denotes male kidney MESH:D018567
97 1514-1519 Disease denotes fever MESH:D005334
98 1521-1540 Disease denotes shortness of breath MESH:D004417
99 1546-1551 Disease denotes cough MESH:D003371
100 1676-1683 Disease denotes Celsius
101 1796-1804 Disease denotes COVID-19 MESH:C000657245
107 2289-2296 Species denotes patient Tax:9606
108 2320-2330 Chemical denotes prednisone MESH:D011241
109 2334-2352 Chemical denotes methylprednisolone MESH:D008775
110 2435-2443 Chemical denotes cefepime MESH:D000077723
111 2495-2513 Chemical denotes hydroxychloroquine MESH:D006886
116 4524-4542 Gene denotes C-reactive protein Gene:1401
117 4571-4575 Gene denotes IL-6 Gene:3569
118 4812-4823 Species denotes Coronavirus Tax:11118
119 4283-4293 Chemical denotes Creatinine MESH:D003404
121 4027-4034 Species denotes Patient Tax:9606
134 3696-3703 Species denotes patient Tax:9606
135 3214-3225 Chemical denotes tocilizumab MESH:C502936
136 3331-3337 Chemical denotes oxygen MESH:D010100
137 3425-3431 Chemical denotes oxygen MESH:D010100
138 3597-3614 Chemical denotes Mycophenolic acid MESH:D009173
139 3619-3629 Chemical denotes tacrolimus MESH:D016559
140 2556-2561 Disease denotes fever MESH:D005334
141 2646-2665 Disease denotes shortness of breath MESH:D004417
142 2908-2925 Disease denotes viral pneumonitis
143 3089-3097 Disease denotes COVID-19 MESH:C000657245
144 3155-3163 Disease denotes COVID-19 MESH:C000657245
145 3287-3306 Disease denotes shortness of breath MESH:D004417
149 4998-5004 Chemical denotes oxygen MESH:D010100
150 5067-5073 Chemical denotes oxygen MESH:D010100
151 5125-5136 Chemical denotes tocilizumab MESH:C502936
159 5142-5149 Species denotes patient Tax:9606
160 5323-5327 Chemical denotes urea MESH:D014508
161 5328-5336 Chemical denotes nitrogen MESH:D009584
162 5348-5358 Chemical denotes creatinine MESH:D003404
163 5159-5173 Disease denotes critically ill MESH:D016638
164 5251-5263 Disease denotes pneumothorax MESH:D011030
165 5485-5504 Disease denotes bacterial infection MESH:D001424
167 5680-5692 Disease denotes pneumothorax MESH:D011030
196 7460-7464 Gene denotes IL-6 Gene:3569
197 7514-7517 Gene denotes CRP Gene:1401
198 9402-9421 Gene denotes interferon alpha-2b Gene:3440
199 10017-10021 Gene denotes IL-8 Gene:3576
200 7951-7956 Species denotes human Tax:9606
201 7995-8000 Species denotes human Tax:9606
202 9155-9174 Chemical denotes Lopinavir/ritonavir MESH:C558899
203 9369-9378 Chemical denotes Lopinavir MESH:D061466
204 9717-9727 Chemical denotes Prednisone MESH:D011241
205 9728-9763 Chemical denotes BelataceptCyclosporinePrednisoneMMF
206 9872-9882 Chemical denotes Tacrolimus MESH:D016559
207 9883-9912 Chemical denotes Prednisone Hydroxychloroquine
208 9914-9932 Chemical denotes opinavir/ritonavir
209 9934-9945 Chemical denotes ceftriaxone MESH:D002443
210 9947-9957 Chemical denotes tacrolimus MESH:D016559
211 9959-9977 Chemical denotes methlyprednisolone
212 10103-10135 Chemical denotes Prednisone MethylprednisoloneMMF
213 10323-10333 Chemical denotes Tacrolimus MESH:D016559
214 10338-10348 Chemical denotes Prednisone MESH:D011241
215 10349-10357 Chemical denotes Imifovir
216 10359-10371 Chemical denotes Moxifloxacin MESH:D000077266
217 10372-10390 Chemical denotes Methylprednisolone MESH:D008775
218 10392-10400 Chemical denotes Biapenem MESH:C065257
219 7586-7593 Disease denotes Illness MESH:D002908
220 9253-9264 Disease denotes lymphopenia MESH:D008231
221 10092-10102 Disease denotes Kidney MMF MESH:D007674
222 10255-10260 Disease denotes death MESH:D003643
223 10268-10287 Disease denotes multi-organ failure MESH:D009102
229 7284-7287 Gene denotes CRP Gene:1401
230 7290-7308 Gene denotes C-reactive protein Gene:1401
231 7215-7223 Species denotes patients Tax:9606
232 7231-7252 Chemical denotes Mycophenolate Mofetil MESH:D009173
233 7192-7200 Disease denotes COVID 19 MESH:C000657245
255 5791-5801 Species denotes SARS-CoV-2 Tax:2697049
256 5827-5844 Species denotes novel coronavirus Tax:2697049
257 6063-6080 Species denotes novel Coronavirus Tax:2697049
258 6143-6151 Species denotes patients Tax:9606
259 6305-6313 Species denotes patients Tax:9606
260 6449-6457 Species denotes patients Tax:9606
261 6601-6609 Species denotes patients Tax:9606
262 6790-6798 Species denotes patients Tax:9606
263 6944-6952 Species denotes patients Tax:9606
264 7093-7101 Species denotes patients Tax:9606
265 5755-5787 Disease denotes Severe Acute Respiratory Disease MESH:D045169
266 5983-5991 Disease denotes COVID-19 MESH:C000657245
267 6014-6020 Disease denotes deaths MESH:D003643
268 6186-6195 Disease denotes mortality MESH:D003643
269 6567-6575 Disease denotes Covid-19 MESH:C000657245
270 6665-6670 Disease denotes fever MESH:D005334
271 6851-6856 Disease denotes fever MESH:D005334
272 6858-6863 Disease denotes cough MESH:D003371
273 6865-6872 Disease denotes myalgia MESH:D063806
274 6873-6880 Disease denotes fatigue MESH:D005221
275 7034-7042 Disease denotes COVID-19 MESH:C000657245
288 11145-11163 Gene denotes C-reactive protein Gene:1401
289 11165-11168 Gene denotes CRP Gene:1401
290 11296-11309 Gene denotes Interleukin-6 Gene:3569
291 11311-11315 Gene denotes IL-6 Gene:3569
292 11282-11290 Species denotes patients Tax:9606
293 10656-10664 Disease denotes COVID-19 MESH:C000657245
294 10713-10721 Disease denotes COVID-19 MESH:C000657245
295 10730-10765 Disease denotes acute respiratory distress syndrome MESH:D012128
296 10767-10771 Disease denotes ARDS MESH:D012128
297 10783-10791 Disease denotes infected MESH:D007239
298 10889-10900 Disease denotes lymphopenia MESH:D008231
299 11273-11281 Disease denotes COVID-19 MESH:C000657245
311 11424-11428 Gene denotes IL-6 Gene:3569
312 11611-11615 Gene denotes IL-6 Gene:3569
313 11631-11636 Gene denotes IL-6R Gene:3570
314 11664-11667 Gene denotes IL6 Gene:3569
315 11668-11672 Gene denotes IL6R Gene:3570
316 11704-11709 Gene denotes gp130 Gene:3572
317 11820-11824 Gene denotes IL-6 Gene:3569
318 11870-11873 Gene denotes IL6 Gene:3569
319 11911-11916 Gene denotes gp130 Gene:3572
320 12066-12069 Gene denotes sIL Gene:6491
321 12104-12109 Gene denotes gp130 Gene:3572
331 12252-12256 Gene denotes IL-6 Gene:3569
332 12391-12395 Gene denotes IL-6 Gene:3569
333 12496-12500 Gene denotes IL-6 Gene:3569
334 12624-12628 Gene denotes IL-6 Gene:3569
335 12218-12226 Species denotes patients Tax:9606
336 12648-12656 Species denotes patients Tax:9606
337 12365-12376 Disease denotes lymphopenia MESH:D008231
338 12406-12414 Disease denotes COVID-19 MESH:C000657245
339 12639-12647 Disease denotes COVID-19 MESH:C000657245
343 12905-12910 Gene denotes IL-6R Gene:3570
344 12785-12796 Chemical denotes tocilizumab MESH:C502936
345 12912-12923 Chemical denotes tocilizumab MESH:C502936
357 13884-13888 Gene denotes IL-6 Gene:3569
358 13994-13998 Gene denotes IL-6 Gene:3569
359 13429-13437 Species denotes patients Tax:9606
360 13452-13463 Chemical denotes tocilizumab MESH:C502936
361 13587-13596 Chemical denotes lopinavir MESH:D061466
362 13598-13616 Chemical denotes methylprednisolone MESH:D008775
363 13647-13653 Chemical denotes oxygen MESH:D010100
364 13899-13912 Chemical denotes metronidazole MESH:D008795
365 13964-13977 Chemical denotes metronidazole MESH:D008795
366 13157-13165 Disease denotes COVID-19 MESH:C000657245
367 13554-13562 Disease denotes Covid-19 MESH:C000657245
378 15012-15016 Gene denotes IL-6 Gene:3569
379 14474-14482 Species denotes patients Tax:9606
380 14572-14580 Species denotes patients Tax:9606
381 14076-14084 Disease denotes infected MESH:D007239
382 14090-14098 Disease denotes COVID-19 MESH:C000657245
383 14552-14556 Disease denotes ARDS MESH:D012128
384 14567-14571 Disease denotes SARS MESH:D045169
385 14742-14746 Disease denotes ARDS MESH:D012128
386 14858-14866 Disease denotes COVID-19 MESH:C000657245
387 15086-15094 Disease denotes COVID-19 MESH:C000657245
396 15151-15155 Gene denotes IL-6 Gene:3569
397 15287-15291 Gene denotes IL-6 Gene:3569
398 15531-15535 Gene denotes IL-6 Gene:3569
399 15363-15371 Species denotes patients Tax:9606
400 15484-15492 Species denotes patients Tax:9606
401 15569-15579 Chemical denotes tacrolimus MESH:D016559
402 15185-15193 Disease denotes COVID-19 MESH:C000657245
403 15807-15815 Disease denotes COVID-19 MESH:C000657245
412 16171-16175 Gene denotes IL-6 Gene:3569
413 15909-15917 Species denotes patients Tax:9606
414 16027-16034 Species denotes patient Tax:9606
415 16309-16317 Species denotes patients Tax:9606
416 16422-16433 Chemical denotes tocilizumab MESH:C502936
417 15923-15931 Disease denotes COVID-19 MESH:C000657245
418 16116-16136 Disease denotes respiratory distress MESH:D012128
419 16334-16341 Disease denotes hypoxic MESH:D000860
434 16697-16701 Gene denotes IL-6 Gene:3569
435 16630-16638 Species denotes patients Tax:9606
436 16719-16726 Species denotes patient Tax:9606
437 16863-16870 Species denotes patient Tax:9606
438 16977-16985 Species denotes patients Tax:9606
439 17293-17301 Species denotes patients Tax:9606
440 16811-16822 Chemical denotes tocilizumab MESH:C502936
441 16621-16629 Disease denotes COVID-19 MESH:C000657245
442 16899-16918 Disease denotes respiratory failure MESH:D012131
443 17076-17096 Disease denotes respiratory distress MESH:D012128
444 17113-17137 Disease denotes Thromboembolic phenomena MESH:D013923
445 17168-17187 Disease denotes respiratory failure MESH:D012131
446 17284-17292 Disease denotes COVID-19 MESH:C000657245
447 17402-17410 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T5 390-410 Phenotype denotes Respiratory Distress http://purl.obolibrary.org/obo/HP_0002098
T6 590-604 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T7 1316-1330 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T8 1509-1519 Phenotype denotes mild fever http://purl.obolibrary.org/obo/HP_0011134
T9 1521-1540 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T10 1546-1551 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T11 2556-2561 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T12 2646-2665 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T13 3287-3306 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T14 5251-5263 Phenotype denotes pneumothorax http://purl.obolibrary.org/obo/HP_0002107
T15 5680-5692 Phenotype denotes pneumothorax http://purl.obolibrary.org/obo/HP_0002107
T16 6665-6670 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T17 6851-6856 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T18 6858-6863 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T19 6865-6872 Phenotype denotes myalgia http://purl.obolibrary.org/obo/HP_0003326
T20 6873-6880 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T21 6969-6989 Phenotype denotes abdominal discomfort http://purl.obolibrary.org/obo/HP_0002027
T22 9253-9264 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T23 10736-10756 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T24 10889-10900 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T25 11014-11028 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T26 11403-11417 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T27 12365-12376 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T28 12520-12534 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T29 13052-13066 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T30 14341-14355 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T31 14764-14778 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T32 15045-15059 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T33 15655-15669 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T34 15962-15976 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T35 15987-16001 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T36 16116-16136 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T37 16899-16918 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T38 16924-16938 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T39 17076-17096 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T40 17113-17127 Phenotype denotes Thromboembolic http://purl.obolibrary.org/obo/HP_0001907
T41 17168-17187 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 563-575 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T2 884-906 http://purl.obolibrary.org/obo/GO_0002456 denotes cell-mediated immunity
T3 884-906 http://purl.obolibrary.org/obo/GO_0002449 denotes cell-mediated immunity
T4 926-940 http://purl.obolibrary.org/obo/GO_0019076 denotes viral shedding
T5 4441-4452 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T6 11429-11448 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T7 11436-11448 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T8 11491-11510 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T9 11498-11510 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T10 11518-11537 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T11 11525-11537 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T12 11582-11601 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T13 11589-11601 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T14 11631-11636 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6R
T15 11668-11672 http://purl.obolibrary.org/obo/GO_0004915 denotes IL6R
T16 11704-11709 http://purl.obolibrary.org/obo/GO_0004921 denotes gp130
T17 11704-11709 http://purl.obolibrary.org/obo/GO_0004915 denotes gp130
T18 11704-11709 http://purl.obolibrary.org/obo/GO_0004897 denotes gp130
T19 11751-11763 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T20 11780-11799 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T21 11787-11799 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T22 11911-11916 http://purl.obolibrary.org/obo/GO_0004921 denotes gp130
T23 11911-11916 http://purl.obolibrary.org/obo/GO_0004915 denotes gp130
T24 11911-11916 http://purl.obolibrary.org/obo/GO_0004897 denotes gp130
T25 11939-11972 http://purl.obolibrary.org/obo/GO_0035556 denotes intracellular signal transduction
T26 11953-11972 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T27 11960-11972 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T28 12104-12109 http://purl.obolibrary.org/obo/GO_0004921 denotes gp130
T29 12104-12109 http://purl.obolibrary.org/obo/GO_0004915 denotes gp130
T30 12104-12109 http://purl.obolibrary.org/obo/GO_0004897 denotes gp130
T31 12143-12147 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T32 12905-12910 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6R
T33 12965-12983 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T34 12965-12974 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T35 14153-14168 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T36 15292-15311 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T37 15299-15311 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T38 15849-15871 http://purl.obolibrary.org/obo/GO_0019048 denotes virus-host interaction

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T8 0-12 Sentence denotes Introduction
T9 13-197 Sentence denotes As of May 14, 2020, the World Health Organization has reported 4,248,386 cases of COVID-19 with 294,046 reported deaths secondary to complications related to the novel Coronavirus [1].
T10 198-327 Sentence denotes In the United States, the Center for Disease Control (CDC) reported 1,364,061 total cases and 82,246 COVID-19 related deaths [2].
T11 328-487 Sentence denotes A common complication reported secondary to COVID-19 is Acute Respiratory Distress Syndrome (ARDS) requiring endotracheal intubation and ventilator management.
T12 488-630 Sentence denotes Experts currently believe that ARDS possibly results from a state of hyper-inflammation mediated by a cytokine storm in COVID-19 patients [3].
T13 631-827 Sentence denotes Recipients of solid organ transplants are included in a special population of patients who may face increased risks of COVID-19 related complications given their use of chronic immunosuppressants.
T14 828-998 Sentence denotes Immunosuppression in this population can further reduce cell-mediated immunity, which may prolong viral shedding and increase the risk of COVID related complications [3].
T15 999-1189 Sentence denotes As reported by McGonagle et al., interleukin-6 (IL-6) plays an important role in lung repair following viral insults and the administration of IL-6 inhibitor drugs may be time-sensitive [3].
T16 1190-1347 Sentence denotes We report a case of COVID-19 in a patient with kidney and liver transplant and discuss the use of IL-6 inhibitor to prevent a cytokine storm in this setting.
T17 1349-1360 Sentence denotes Case report
T18 1361-1552 Sentence denotes The patient is a 63-year-old male kidney and liver transplant recipient who presented to the Emergency Department (ED) after developing symptoms of mild fever, shortness of breath, and cough.
T19 1553-1684 Sentence denotes His vitals and physical exam in the Emergency Department were within normal limits, except for a temperature of 38 degrees Celsius.
T20 1685-1758 Sentence denotes His initial chest x-ray on the day of admission (Day 1) was unremarkable.
T21 1759-1874 Sentence denotes He tested negative for influenza and COVID-19 via polymerase chain reaction (PCR) and was admitted to the hospital.
T22 1875-2037 Sentence denotes At the time of admission, he had a normal white blood cell count (6.94 × 109/liter), decreased absolute lymphocyte count (2.9 %), and normal liver function tests.
T23 2038-2101 Sentence denotes Cytomegalovirus and Bordetella PCR serology were also negative.
T24 2102-2257 Sentence denotes His home immunosuppressant regimen consisted of mycophenolic acid 500 milligrams daily, prednisone 5 milligrams daily, tacrolimus 2 milligrams twice a day.
T25 2258-2412 Sentence denotes On day 2 of the admission, the patient was switched from oral prednisone to methylprednisolone 40 milligrams administered every eight hours intravenously.
T26 2413-2463 Sentence denotes On day 3, he received cefepime 1 g over six hours.
T27 2464-2541 Sentence denotes He also received five doses of hydroxychloroquine 400 milligrams on days 3–7.
T28 2542-2612 Sentence denotes On day 4, the fever subsided and vitals remained within normal limits.
T29 2613-2719 Sentence denotes However, he developed increasing shortness of breath with new diffuse expiratory wheezes on physical exam.
T30 2720-2926 Sentence denotes Repeat chest x-ray showed right lower lobe infiltrates and CT Thorax without contrast showed right upper, middle, and lower lobe infiltrates with ground glass appearance consistent with a viral pneumonitis.
T31 2927-3079 Sentence denotes This later progressed to bilateral ground glass opacities as pictured in Fig. 1, Fig. 2, Fig. 3 and warranted transfer to the Intensive Care Unit (ICU).
T32 3080-3179 Sentence denotes Test for COVID-19 serum antibodies performed at this time was positive for COVID-19 IgG antibodies.
T33 3180-3240 Sentence denotes On Day 4, he received one dose of tocilizumab 4 mL/kilogram.
T34 3241-3326 Sentence denotes Within 24 h of receiving this medication, his shortness of breath started to improve.
T35 3327-3477 Sentence denotes His oxygen requirement dropped to 2–3 liters via nasal cannula with exercise while maintaining an oxygen saturation of 86–94 % over the next two days.
T36 3478-3539 Sentence denotes His chest x-ray also showed improvement, as shown in Fig. 4 .
T37 3540-3596 Sentence denotes Overall, he began to show clinical signs of improvement.
T38 3597-3657 Sentence denotes Mycophenolic acid and tacrolimus were discontinued on day 5.
T39 3658-3754 Sentence denotes Table 1 shows the lab results for the patient through the first seven days of his hospital stay.
T40 3755-3823 Sentence denotes Fig. 1 CT Thorax without contrast: bilateral ground glass opacities.
T41 3824-3892 Sentence denotes Fig. 2 CT Thorax without contrast: bilateral ground glass opacities.
T42 3893-3961 Sentence denotes Fig. 3 CT Thorax without contrast: bilateral ground glass opacities.
T43 3962-4018 Sentence denotes Fig. 4 Chest x-ray improved after six days of treatment.
T44 4019-4054 Sentence denotes Table 1 Patient labs from Day 1–10.
T45 4055-4182 Sentence denotes Labratory Test Results 4/11/20Day 1 4/13/20day 3 4/14/20day 4 4/15/20day 5 4/16/20day 6 4/17/20day 7 4/18/20day 8 4/20/20day 10
T46 4183-4233 Sentence denotes WBC(4.5–11 × 109/L) 6.94 6.73 12.13 8.27 8.03 8.89
T47 4234-4282 Sentence denotes Lymphocytes(30–45 %) 2.90 % 3.70 % 3.30 % 6.50 %
T48 4283-4299 Sentence denotes Creatinine(Male:
T49 4300-4351 Sentence denotes 0.70−1.30 mg/dL) 1.20 1.30 1.50 1.10 1.00 0.90 0.90
T50 4352-4391 Sentence denotes AST(10−40 units/L) 21 25 29 34 37 25 22
T51 4392-4431 Sentence denotes ALT(10−40 units/L) 29 26 28 45 64 53 51
T52 4432-4489 Sentence denotes Alkaline phosphatase(30−120 units/L) 81 75 72 68 63 63 72
T53 4490-4523 Sentence denotes LDH(80–225 units/L) 226.00 344.00
T54 4524-4570 Sentence denotes C-reactive protein (<0.8 mg/dL) 3.70 1.20 0.60
T55 4571-4610 Sentence denotes IL-6(5−15 pg/mL) 18.2 670.8 392.8 280.7
T56 4611-4670 Sentence denotes Prograf/ Tacrolimus levels(5.0−15.0 ng/mL) 17.30 14.80 7.90
T57 4671-4685 Sentence denotes Ferritin(male:
T58 4686-4714 Sentence denotes 54–755 pmol/L) 336.50 225.90
T59 4715-4749 Sentence denotes VBG pH 7.47pO2 81pCO2 32HCO3 23.20
T60 4750-4783 Sentence denotes ABG pH 7.42pO2 72pCO2 33HCO3 21.4
T61 4784-4792 Sentence denotes Serology
T62 4793-4811 Sentence denotes Influenza Negative
T63 4812-4841 Sentence denotes Coronavirus Negative Positive
T64 4842-4926 Sentence denotes However, on Day 7, he decompensated requiring intubation and mechanical ventilation.
T65 4927-4983 Sentence denotes The critical care team also placed him on a rotator bed.
T66 4984-5081 Sentence denotes On day 8, his oxygen requirements substantially increased requiring an increase of oxygen to 1 L.
T67 5082-5137 Sentence denotes At this time, he received a second dose of tocilizumab.
T68 5138-5195 Sentence denotes The patient remained critically ill following intubation.
T69 5196-5290 Sentence denotes Seven days after intubation he developed a right sided pneumothorax and required a chest tube.
T70 5291-5375 Sentence denotes The liver function tests, blood urea nitrogen (BUN), and creatinine remained stable.
T71 5376-5446 Sentence denotes During his ICU stay, he was fully therapeutically heparinized as well.
T72 5447-5505 Sentence denotes He developed no evidence of secondary bacterial infection.
T73 5506-5573 Sentence denotes We obtained consent and administered 200 mL of convalescent plasma.
T74 5574-5664 Sentence denotes He remained stable without significant change in his condition over the next several days.
T75 5665-5742 Sentence denotes On Day 14, the pneumothorax resolved and he began weaning off the ventilator.
T76 5744-5754 Sentence denotes Discussion
T77 5755-5900 Sentence denotes Severe Acute Respiratory Disease 2 (SARS-CoV-2) is a highly infectious, novel coronavirus that emerged in Wuhan, China in December of 2019 [4,5].
T78 5901-6085 Sentence denotes As of May 14, 2020, the World Health Organization has reported 4,248,386 cases of COVID-19 with 294,046 reported deaths secondary to complications related to the novel Coronavirus [1].
T79 6086-6227 Sentence denotes While this lethal disease has not spared immunocompetent patients, populations who have the highest mortality risk require special attention.
T80 6228-6318 Sentence denotes At this time, there are limited case reports on solid organ transplant (SOT) patients [6].
T81 6319-6442 Sentence denotes There is insufficient data on the clinical presentation and management of immunosuppressant regimens in SOT recipients [4].
T82 6443-6580 Sentence denotes These patients may differ from the immunocompetent population in regards to presentation, diagnosis, and clinical course of Covid-19 [4].
T83 6581-6671 Sentence denotes Notably, transplant patients may present with mild or atypical symptoms and without fever.
T84 6672-6765 Sentence denotes Thus, physicians must maintain broad differential diagnoses and high clinical suspicions [7].
T85 6766-6908 Sentence denotes One case series of five patients reported the most common symptoms on admission were fever, cough, myalgia/fatigue, and sputum production [5].
T86 6909-6994 Sentence denotes Other case reports have identified patients as having vague abdominal discomfort [4].
T87 6995-7061 Sentence denotes Table 2 outlines the reported cases on COVID-19 in SOT recipients.
T88 7062-7165 Sentence denotes We did not find any reports of patients with double solid organ transplants reported in the literature.
T89 7166-7224 Sentence denotes Table 2 Reported cases of COVID 19 in transplant patients.
T90 7225-7253 Sentence denotes MMF = Mycophenolate Mofetil.
T91 7254-7283 Sentence denotes WBC = White blood cell count.
T92 7284-7309 Sentence denotes CRP = C-reactive protein.
T93 7310-7338 Sentence denotes LDH = lactate dehydrogenase.
T94 7339-7602 Sentence denotes Age/ Sex Solid Organ Transplant ChronicImmunomodulator Medications given during admission while receivingCOVID treatment IL-6 levels WBC(4.5–11 × 109/L) Lymphocytes (30–45 %) CRP(<0.8 mg/dL; <76.2 nmol/L) LDH(80–225 units/L) Outcome Total Days of Illness Citation
T95 7603-7872 Sentence denotes 37M Liver Tacrolimus Oseltamivir, phosphate capsules, cefoperazonesulbactam sodium, methylprednisoloneTacrolimus discontinued Not Reported 2.46 48% Not reported Not Reported Acute transplant rejection, but recovered after tacrolimus was resumedFull recovery 15 days [4]
T96 7873-8133 Sentence denotes 48M Kidney, 2003 Tacrolimus MMF Oseltamivir, abidol moxifloxacin, recombinant human interferon alpha, methylprednisolone, human IVIG TacrolimusMMF discontinued Not Reported 2.49 64% 31.25 Not Reported Bone marrow suppression due to MMFFull recovery 42 days [4]
T97 8134-8301 Sentence denotes 38M Kidney, 2019 Glucocorticoid MMF Tacrolimus Oseltamivir, arbidol Glucocorticoids TacrolimusMMF discontinued Not Reported 4.73 63% 0.37 193 Full recovery 26 days [5]
T98 8302-8502 Sentence denotes 64M Kidney, 2016 Glucocorticoid MMF rapamycin Oseltamivir or arbidol cefepime and IVIG Glucocorticoids TacrolimusMMF discontinued Not Reported 17.67 55% 1.26 180 Remained hospitalized Not Reported [5]
T99 8503-8738 Sentence denotes 37F Kidney, 2019 Glucocorticoid MMF Tacrolimus Oseltamivir or arbidol cefepimeIVIG GlucocorticoidsMMF discontinuedTacrolimus discontinued, then restarted at half the dose Not Reported 5.67 31% 2.03 160 Remained hospitalized 22 days [5]
T100 8739-8942 Sentence denotes 47M Kidney, 2019 Glucocorticoid MMF Tacrolimus Oseltamivir or arbidol GlucocorticoidsMMF discontinuedTacrolimus stopped and restarted Not Reported 3.99 51% 0.45 235 Remained hospitalized Not Reported [5]
T101 8943-9100 Sentence denotes 38M Kidney, 2017 Glucocorticoid MMF Tacrolimus Oseltamivir or arbidol Glucocorticoids MMF Tacrolimus Not Reported 6.44 91% 0.39 248 Full recovery 23 days [5]
T102 9101-9142 Sentence denotes 50 M Liver Tacrolimus Methylprednisolone.
T103 9143-9329 Sentence denotes Umifenovir, Lopinavir/ritonavir,IVIG,Cefoperazone, alpha interferonTacrolimus discontinued for 4 weeks due to lymphopenia Not Reported 5.9 72% 32.1 Not Reported Full recovery 28 days [6]
T104 9330-9551 Sentence denotes 49M Kidney Cyclosporine MMF Prednisone Lopinavir, ritonavir, ribavirin, interferon alpha-2b, methylprednisolone, MMF, prednisoneCyclosporine discontinued Not Reported 7.18 59% 22.73 Not Reported Full recovery 14 days [19]
T105 9552-9684 Sentence denotes 50M Kidney, 1992, 2016 MMF Tacrolimus MMF, Tacrolimus,ceftriaxone 26.22 3.2 60% Not Reported Not Reported Full recovery 13 days [17]
T106 9685-9848 Sentence denotes 58M Kidney, 2017 Belatacept MMF Prednisone BelataceptCyclosporinePrednisoneMMF discontinued during treatment 29 5.04 16% 14 Not Reported Full recovery 18 days [20]
T107 9849-10087 Sentence denotes 36F Kidney, 1993, 1995 Tacrolimus Prednisone Hydroxychloroquine, opinavir/ritonavir, ceftriaxone, tacrolimus, methlyprednisolone Within normal limits(reported elevated IL-8) High neutrophil normal 67 Not Reported Full recovery 9 days [21]
T108 10088-10310 Sentence denotes 58M Kidney MMF Prednisone MethylprednisoloneMMF discontinued during treatment Not Reported Not Reported Not Reported Not Reported Not Reported Mechanical ventilation; death due to multi-organ failure on Day 40 40 days [22]
T109 10311-10483 Sentence denotes 52 M Kidney Tacrolimus MMF Prednisone Imifovir, Moxifloxacin Methylprednisolone, Biapenem, interferon alphaAll immunosuppressive agents discontinued during treatment Day 2:
T110 10484-10496 Sentence denotes 19.53 Day 2:
T111 10497-10522 Sentence denotes 5.54; Day 11 11.68 Day 2:
T112 10523-10537 Sentence denotes 17.9 % Day 11:
T113 10538-10549 Sentence denotes 12 % Day 2:
T114 10550-10561 Sentence denotes 54; Day 11:
T115 10562-10605 Sentence denotes 1.4 Not Reported Full recovery 18 days [23]
T116 10606-10777 Sentence denotes Recent proposals regarding the pathophysiology of COVID-19 suggest a hyper-inflammatory state resulting in COVID-19 related acute respiratory distress syndrome (ARDS) [3].
T117 10778-10905 Sentence denotes Once infected, there is loss of primary antiviral defense because of virus-induced interferon suppression with lymphopenia [8].
T118 10906-11058 Sentence denotes Subsequently, the body activates a second defense mechanism, known as the “second wave,” which results in a cytokine storm and severe tissue damage [3].
T119 11059-11295 Sentence denotes Increases in many inflammatory markers, such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), serum ferritin, interleukins 6, 8, and 10, procalcitonin, and interleukin-receptor have been found in COVID-19 patients [9].
T120 11296-11423 Sentence denotes Interleukin-6 (IL-6) is a marker of recent interest because of its role in the “second wave” and resulting cytokine storm. [10]
T121 11424-11567 Sentence denotes IL-6 signal transduction occurs via three main pathways: classical signal transduction, trans signal transduction, and trans presentation [11].
T122 11568-11769 Sentence denotes The classical signal transduction involves IL-6 binding to the IL-6R and forming a complex; the IL6-IL6R complex then binds to membrane gp130 and subsequently initiates intracellular transduction [11].
T123 11770-11978 Sentence denotes The trans signal transduction pathway occurs with IL-6 binding to sIL-6R and forming a complex; the IL6-sIL6R complex then binds to membrane gp130, which then initiates intracellular signal transduction [11].
T124 11979-12181 Sentence denotes The trans presentation signal involves sgp130 forming a complex with sIL-6R to prevent sIL-6R from binding to membrane-bound gp130; the JAK-STATA, RAS-RAF, and ATK-PI3K pathways are then activated [11].
T125 12182-12307 Sentence denotes Chen et al. found in a sample of 48 patients that increased levels of IL-6 significantly correlated to disease severity [12].
T126 12308-12561 Sentence denotes Another study reported a significant association between lymphopenia and increased IL-6 levels in COVID-19 non-survivors compared with survivors. [12,13] These findings suggest monitoring IL-6 levels to evaluate cytokine storm as a prognostic tool [12].
T127 12562-12769 Sentence denotes However, it is likely that physicians do not routinely follow IL-6 levels in COVID-19 patients with solid organ transplants, as it was not a commonly reported lab value in the studies we evaluated (Table 2).
T128 12770-12886 Sentence denotes Treatment with tocilizumab, a monoclonal antibody that binds to the IL-6 Receptor, has been recently published [11].
T129 12887-13072 Sentence denotes By binding to the IL-6R, tocilizumab can inhibit both the classical and trans signaling pathways leading to a reduction in the “second wave” response and preventing cytokine storm [11].
T130 13073-13301 Sentence denotes The standard treatment dosing according to the Diagnosis and Treatment Protocol for COVID-19 (7th Edition) is a first dose of 4−8 mg/kg/day, with 400 mg diluted to 100 mL with 0.9 % normal saline, infused over a 1 h period [14].
T131 13302-13384 Sentence denotes The maximal dose is 800 mg, and the maximal number of administrations is two [14].
T132 13385-13667 Sentence denotes This dosing is based on a small trial of 21 patients that received tocilizumab, in addition to the standard care recommended by the Diagnosis and Treatment Protocol for Covid-19 (6th Edition) including lopinavir, methylprednisolone, other symptom relievers, and oxygen therapy [15].
T133 13668-13741 Sentence denotes Given the small sample size, we need more research on appropriate dosing.
T134 13742-13839 Sentence denotes At this time, there is a multicenter randomized controlled trial currently ongoing in China [16].
T135 13840-13918 Sentence denotes Another potential medication that decreases IL-6 levels is metronidazole [13].
T136 13919-14011 Sentence denotes In vitro and in vivo studies have shown that metronidazole decreases serum IL-6 levels [13].
T137 14012-14112 Sentence denotes Close monitoring of immunosuppressive therapy in SOT recipients infected with COVID-19 is necessary.
T138 14113-14228 Sentence denotes There is a balance of allowing adequate immune response to suppress viral load and preventing transplant rejection.
T139 14229-14361 Sentence denotes Previous case reports have hypothesized that immunosuppressive therapy protects SOT recipients by dampening the cytokine storm [17].
T140 14362-14487 Sentence denotes Other case reports have noted that viral RNA levels remain positive for a longer period than in immunocompetent patients [4].
T141 14488-14617 Sentence denotes This is notable because previous studies have demonstrated that ARDS occurs in SARS patients despite a decreased viral load [18].
T142 14618-14784 Sentence denotes This is important because it indicates antiviral therapy alone is inadequate treatment and supports the hypothesis that the ARDS results from the cytokine storm [18].
T143 14785-14984 Sentence denotes One case report of a liver transplant recipient that tested positive for COVID-19 suffered from acute transplant rejection despite maintaining adequate immunosuppression based on lymphocyte subtests.
T144 14985-15120 Sentence denotes 4 This suggests that early IL-6 intervention to prevent the cytokine storm could improve outcomes in COVID-19 positive, SOT recipients.
T145 15121-15257 Sentence denotes One of the main concerns with IL-6 blockade in the treatment of COVID-19, however, is the appropriate timing of when to start treatment.
T146 15258-15359 Sentence denotes It is possible that blocking IL-6 signal transduction can lead to a reduction in viral clearance [3].
T147 15360-15493 Sentence denotes In patients that are already immunosuppressed, this could lead to a much higher viral load as compared with immunocompetent patients.
T148 15494-15580 Sentence denotes Additionally, we do not know whether IL-6 alters the levels of circulating tacrolimus.
T149 15581-15682 Sentence denotes This may suggest cessation of immunosuppressive therapy until the initial cytokine storm as resolved.
T150 15683-15872 Sentence denotes Temporary removal of immunosuppressive regiment is likely beneficial for transplant recipients because clinical outcomes of COVID-19 seems to mostly dependent on the virus-host interaction.
T151 15873-15977 Sentence denotes Another interesting finding in many patients with COVID-19 is the potential for a second cytokine storm.
T152 15978-16166 Sentence denotes A second cytokine storm may have happened to the patient in this case report as he clinically improved and then developed a recurrence of respiratory distress that required the intubation.
T153 16167-16264 Sentence denotes The IL-6 levels were also markedly elevated at this time suggesting an ongoing cytokine response.
T154 16265-16376 Sentence denotes This may be the reason why several of these patients become severely hypoxic after a few days of stabilization.
T155 16377-16512 Sentence denotes This may also suggest that we administer the tocilizumab in an interval fashion, approximately 4–6 days after the first administration.
T156 16513-16685 Sentence denotes In conclusion, there is limited data on the clinical presentation, management, and appropriate treatment of COVID-19 patients who are recipients of solid organ transplants.
T157 16686-16919 Sentence denotes The use of IL-6 inhibitor in our patient resulted in clinical improvement initially, but it is difficult to determine if the tocilizumab played a role in the management of this patient, specifically in preventing respiratory failure.
T158 16920-17112 Sentence denotes The cytokine storm appears to play a major role in these patients, and it is possible that several of them experience a second storm that results in severe respiratory distress and intubation.
T159 17113-17188 Sentence denotes Thromboembolic phenomena also appear to play a role in respiratory failure.
T160 17189-17331 Sentence denotes A single case does not represent the complex strategy needed when considering the treatment of COVID-19 patients with solid organ transplants.
T161 17332-17434 Sentence denotes Further studies are necessary to investigate treatment modalities for COVID-19 in special populations.

2_test

Id Subject Object Predicate Lexical cue
32685369-32108352-46476501 13835-13837 32108352 denotes 16
T96720 13835-13837 32108352 denotes 16