PMC:7314078 / 112-2794
Annnotations
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T1","span":{"begin":462,"end":472},"obj":"Disease"},{"id":"T2","span":{"begin":493,"end":502},"obj":"Disease"},{"id":"T3","span":{"begin":546,"end":570},"obj":"Disease"},{"id":"T4","span":{"begin":572,"end":582},"obj":"Disease"},{"id":"T5","span":{"begin":655,"end":688},"obj":"Disease"},{"id":"T6","span":{"begin":690,"end":694},"obj":"Disease"},{"id":"T7","span":{"begin":1074,"end":1082},"obj":"Disease"},{"id":"T8","span":{"begin":1148,"end":1156},"obj":"Disease"},{"id":"T9","span":{"begin":1321,"end":1329},"obj":"Disease"},{"id":"T10","span":{"begin":1975,"end":1983},"obj":"Disease"},{"id":"T11","span":{"begin":2060,"end":2068},"obj":"Disease"},{"id":"T12","span":{"begin":2162,"end":2184},"obj":"Disease"},{"id":"T13","span":{"begin":2315,"end":2323},"obj":"Disease"},{"id":"T14","span":{"begin":2548,"end":2556},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0004995"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T2","span":{"begin":123,"end":124},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T3","span":{"begin":914,"end":920},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T4","span":{"begin":938,"end":943},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T5","span":{"begin":987,"end":995},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T6","span":{"begin":1201,"end":1202},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T7","span":{"begin":1339,"end":1342},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T8","span":{"begin":1657,"end":1660},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T9","span":{"begin":1726,"end":1727},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T10","span":{"begin":1810,"end":1815},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T11","span":{"begin":2044,"end":2045},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T12","span":{"begin":2275,"end":2276},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":1996,"end":2004},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"5","span":{"begin":25,"end":42},"obj":"Species"},{"id":"6","span":{"begin":237,"end":243},"obj":"Species"},{"id":"7","span":{"begin":462,"end":481},"obj":"Disease"},{"id":"18","span":{"begin":632,"end":640},"obj":"Species"},{"id":"19","span":{"begin":655,"end":699},"obj":"Species"},{"id":"20","span":{"begin":901,"end":909},"obj":"Species"},{"id":"21","span":{"begin":997,"end":1007},"obj":"Species"},{"id":"22","span":{"begin":546,"end":570},"obj":"Disease"},{"id":"23","span":{"begin":572,"end":582},"obj":"Disease"},{"id":"24","span":{"begin":641,"end":649},"obj":"Disease"},{"id":"25","span":{"begin":1074,"end":1082},"obj":"Disease"},{"id":"26","span":{"begin":1148,"end":1156},"obj":"Disease"},{"id":"27","span":{"begin":1229,"end":1250},"obj":"Disease"},{"id":"30","span":{"begin":1376,"end":1384},"obj":"Species"},{"id":"31","span":{"begin":1321,"end":1329},"obj":"Disease"},{"id":"42","span":{"begin":1810,"end":1815},"obj":"Species"},{"id":"43","span":{"begin":1954,"end":1962},"obj":"Species"},{"id":"44","span":{"begin":2069,"end":2077},"obj":"Species"},{"id":"45","span":{"begin":2148,"end":2156},"obj":"Species"},{"id":"46","span":{"begin":2195,"end":2203},"obj":"Species"},{"id":"47","span":{"begin":1975,"end":1983},"obj":"Disease"},{"id":"48","span":{"begin":2060,"end":2068},"obj":"Disease"},{"id":"49","span":{"begin":2123,"end":2131},"obj":"Disease"},{"id":"50","span":{"begin":2162,"end":2184},"obj":"Disease"},{"id":"51","span":{"begin":2315,"end":2323},"obj":"Disease"},{"id":"53","span":{"begin":2548,"end":2556},"obj":"Disease"}],"attributes":[{"id":"A5","pred":"tao:has_database_id","subj":"5","obj":"Tax:2697049"},{"id":"A6","pred":"tao:has_database_id","subj":"6","obj":"Tax:9606"},{"id":"A7","pred":"tao:has_database_id","subj":"7","obj":"MESH:D003141"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"Tax:9606"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"Tax:694009"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"Tax:9606"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"Tax:9606"},{"id":"A22","pred":"tao:has_database_id","subj":"22","obj":"MESH:C000657245"},{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"MESH:C000657245"},{"id":"A24","pred":"tao:has_database_id","subj":"24","obj":"MESH:D007239"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"MESH:C000657245"},{"id":"A26","pred":"tao:has_database_id","subj":"26","obj":"MESH:C000657245"},{"id":"A27","pred":"tao:has_database_id","subj":"27","obj":"MESH:C000657245"},{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"Tax:9606"},{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"MESH:C000657245"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"Tax:9606"},{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"Tax:9606"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"Tax:9606"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Tax:9606"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"Tax:9606"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"MESH:C000657245"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"MESH:C000657245"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"MESH:D007239"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"MESH:D002318"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"MESH:C000657245"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
TEST0
{"project":"TEST0","denotations":[{"id":"32437514-152-157-8062","span":{"begin":165,"end":166},"obj":"[\"32309796\"]"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T2","span":{"begin":0,"end":12},"obj":"Sentence"},{"id":"T3","span":{"begin":13,"end":168},"obj":"Sentence"},{"id":"T4","span":{"begin":169,"end":308},"obj":"Sentence"},{"id":"T5","span":{"begin":309,"end":512},"obj":"Sentence"},{"id":"T6","span":{"begin":513,"end":792},"obj":"Sentence"},{"id":"T7","span":{"begin":793,"end":944},"obj":"Sentence"},{"id":"T8","span":{"begin":945,"end":1034},"obj":"Sentence"},{"id":"T9","span":{"begin":1035,"end":1089},"obj":"Sentence"},{"id":"T10","span":{"begin":1090,"end":1137},"obj":"Sentence"},{"id":"T11","span":{"begin":1138,"end":1273},"obj":"Sentence"},{"id":"T12","span":{"begin":1274,"end":1411},"obj":"Sentence"},{"id":"T13","span":{"begin":1412,"end":1641},"obj":"Sentence"},{"id":"T14","span":{"begin":1642,"end":1799},"obj":"Sentence"},{"id":"T15","span":{"begin":1800,"end":2014},"obj":"Sentence"},{"id":"T16","span":{"begin":2015,"end":2185},"obj":"Sentence"},{"id":"T17","span":{"begin":2186,"end":2261},"obj":"Sentence"},{"id":"T18","span":{"begin":2262,"end":2461},"obj":"Sentence"},{"id":"T19","span":{"begin":2462,"end":2682},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
LitCovid-PD-HP
{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":2162,"end":2184},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001626"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
MyTest
{"project":"MyTest","denotations":[{"id":"32437514-32309796-28906075","span":{"begin":165,"end":166},"obj":"32309796"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
0_colil
{"project":"0_colil","denotations":[{"id":"32437514-32309796-8062","span":{"begin":165,"end":166},"obj":"32309796"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
2_test
{"project":"2_test","denotations":[{"id":"32437514-32309796-28906075","span":{"begin":165,"end":166},"obj":"32309796"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}
testtesttest
{"project":"testtesttest","denotations":[{"id":"T2","span":{"begin":326,"end":333},"obj":"Body_part"},{"id":"T3","span":{"begin":2421,"end":2427},"obj":"Body_part"},{"id":"T4","span":{"begin":2594,"end":2600},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"}],"text":"INTRODUCTION\nThe current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1]. In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago. Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.\nBy the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures. Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus. Consequently, almost all elective medical activity (outpatient and surgical) was stopped. Entire hospitals were transformed into COVID-19 units. In-hospital dedicated pathways were identified. Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.\nThe emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery. The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month). This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.\nAs far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs. Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease. However, patients with cardiac emergencies/urgencies deserve to be treated. So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.\nHerein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency."}