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PMC:7314078 / 112-17483 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 10779-10782 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T2 12467-12479 Body_part denotes aortic valve http://purl.org/sig/ont/fma/fma7236
T3 13249-13261 Body_part denotes Aortic valve http://purl.org/sig/ont/fma/fma7236
T4 13425-13437 Body_part denotes Mitral valve http://purl.org/sig/ont/fma/fma7235
T5 13549-13565 Body_part denotes papillary muscle http://purl.org/sig/ont/fma/fma12154
T6 13697-13700 Body_part denotes LAD http://purl.org/sig/ont/fma/fma3862
T7 14024-14029 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088
T8 14066-14071 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088
T9 14320-14323 Body_part denotes LAD http://purl.org/sig/ont/fma/fma3862
T10 14367-14382 Body_part denotes coronary artery http://purl.org/sig/ont/fma/fma49893
T11 14437-14442 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 12467-12479 Body_part denotes aortic valve http://purl.obolibrary.org/obo/UBERON_0002137
T2 12474-12479 Body_part denotes valve http://purl.obolibrary.org/obo/UBERON_0003978
T3 13249-13261 Body_part denotes Aortic valve http://purl.obolibrary.org/obo/UBERON_0002137
T4 13256-13261 Body_part denotes valve http://purl.obolibrary.org/obo/UBERON_0003978
T5 13425-13437 Body_part denotes Mitral valve http://purl.obolibrary.org/obo/UBERON_0002135
T6 13432-13437 Body_part denotes valve http://purl.obolibrary.org/obo/UBERON_0003978
T7 13965-13970 Body_part denotes valve http://purl.obolibrary.org/obo/UBERON_0003978
T8 14024-14029 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948
T9 14066-14071 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948
T10 14244-14249 Body_part denotes valve http://purl.obolibrary.org/obo/UBERON_0003978
T11 14367-14382 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T12 14376-14382 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T13 14437-14442 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948
T14 16420-16425 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 462-472 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T2 493-502 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T3 546-570 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T4 572-582 Disease denotes COVID-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T5 655-688 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T6 690-694 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T7 1074-1082 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 1148-1156 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 1321-1329 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 1975-1983 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 2060-2068 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 2162-2184 Disease denotes cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0004995
T13 2315-2323 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 2548-2556 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 2688-2696 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 2688-2692 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T17 2843-2854 Disease denotes common cold http://purl.obolibrary.org/obo/MONDO_0005709
T18 2965-2969 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T19 2999-3008 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T20 3032-3040 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T21 3032-3036 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T22 3118-3126 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T23 3128-3136 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 3212-3220 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 3212-3216 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T26 3452-3461 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T27 3528-3536 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 3594-3602 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T29 3799-3807 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 3799-3803 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T31 4020-4029 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T32 4148-4156 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 4505-4513 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T34 4814-4822 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 4814-4818 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T36 5441-5449 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T37 5441-5445 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T38 6770-6774 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T39 6776-6809 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T40 6863-6871 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T41 7022-7031 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T42 7234-7242 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T43 7234-7238 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T44 7451-7459 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 7451-7455 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T46 7541-7550 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T47 7579-7588 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T48 7746-7755 Disease denotes diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T49 7829-7837 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T50 7829-7833 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T51 7920-7929 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T52 7965-7972 Disease denotes obesity http://purl.obolibrary.org/obo/MONDO_0011122
T53 7974-7986 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T54 7991-8008 Disease denotes diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T55 8111-8119 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T56 8111-8115 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T57 8181-8190 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 8398-8406 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T59 9543-9551 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T60 9768-9774 Disease denotes trauma http://purl.obolibrary.org/obo/MONDO_0021178
T61 9776-9782 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T63 9895-9922 Disease denotes acute myocardial infarction http://purl.obolibrary.org/obo/MONDO_0004781
T64 9901-9922 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T65 10739-10763 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T66 10885-10909 Disease denotes coronavirus disease-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T67 11640-11648 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T68 11640-11644 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T69 12134-12142 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T70 12134-12138 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T71 12656-12671 Disease denotes aortic stenosis http://purl.obolibrary.org/obo/MONDO_0004978|http://purl.obolibrary.org/obo/MONDO_0042981
T73 12897-12905 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T74 13035-13041 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T76 13090-13105 Disease denotes aortic aneurysm http://purl.obolibrary.org/obo/MONDO_0005160
T77 13122-13137 Disease denotes aortic aneurysm http://purl.obolibrary.org/obo/MONDO_0005160
T78 13151-13166 Disease denotes Marfan syndrome http://purl.obolibrary.org/obo/MONDO_0007947
T79 13173-13187 Disease denotes collagenopathy http://purl.obolibrary.org/obo/MONDO_0004603
T80 13236-13248 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T81 13270-13285 Disease denotes aortic stenosis http://purl.obolibrary.org/obo/MONDO_0004978|http://purl.obolibrary.org/obo/MONDO_0042981
T83 13357-13377 Disease denotes aortic regurgitation http://purl.obolibrary.org/obo/MONDO_0005648
T84 13446-13461 Disease denotes mitral stenosis http://purl.obolibrary.org/obo/MONDO_0005852
T85 13521-13541 Disease denotes mitral insufficiency http://purl.obolibrary.org/obo/MONDO_0001298
T86 13633-13648 Disease denotes Unstable angina http://purl.obolibrary.org/obo/MONDO_0006805
T87 13697-13700 Disease denotes LAD http://purl.obolibrary.org/obo/MONDO_0017570
T88 13765-13780 Disease denotes cardiac rupture http://purl.obolibrary.org/obo/MONDO_0020983
T89 13787-13799 Disease denotes endocarditis http://purl.obolibrary.org/obo/MONDO_0005025
T90 14024-14037 Disease denotes Heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T91 14066-14079 Disease denotes Heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T92 14138-14155 Disease denotes Cardiac tamponade http://purl.obolibrary.org/obo/MONDO_0001297
T93 14163-14169 Disease denotes myxoma http://purl.obolibrary.org/obo/MONDO_0044784
T94 14284-14292 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 14294-14318 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T96 14320-14323 Disease denotes LAD http://purl.obolibrary.org/obo/MONDO_0017570
T97 15080-15088 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T98 15080-15084 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T99 15122-15130 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T100 15122-15126 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T101 15239-15247 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T102 15283-15291 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T103 15499-15507 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T104 15499-15503 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T105 15910-15918 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T106 15910-15914 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T107 16116-16125 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T108 16395-16403 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T109 16922-16930 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T2 123-124 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 914-920 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T4 938-943 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T5 987-995 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T6 1201-1202 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1339-1342 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T8 1657-1660 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T9 1726-1727 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1810-1815 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T11 2044-2045 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 2275-2276 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T13 2757-2764 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T14 2769-2775 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T15 2783-2790 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T16 3041-3045 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2, a
T17 3095-3101 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T18 3103-3106 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T19 3156-3161 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T20 3226-3227 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 3232-3237 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T22 3415-3427 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T23 3507-3508 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 3603-3604 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 3683-3684 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T26 3697-3699 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T27 3835-3836 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 3901-3902 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 3977-3978 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 4101-4104 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T31 4680-4690 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T32 4889-4894 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T33 4901-4902 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 5075-5082 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T35 5582-5584 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T36 5596-5598 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T37 5634-5637 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T38 5724-5727 http://purl.obolibrary.org/obo/CLO_0001311 denotes 356
T39 5814-5816 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T40 5836-5839 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T41 5836-5839 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T42 5836-5839 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T43 5836-5839 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T44 5836-5839 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T45 5836-5839 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T46 5836-5839 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T47 5921-5923 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T48 6018-6021 http://purl.obolibrary.org/obo/CLO_0001002 denotes 162
T49 6029-6031 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T50 6062-6066 http://purl.obolibrary.org/obo/CLO_0001139 denotes 1871
T51 6319-6323 http://purl.obolibrary.org/obo/CLO_0054053 denotes 1191
T52 6389-6391 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T53 6472-6474 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T54 6500-6503 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T55 6523-6525 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T56 6564-6567 http://purl.obolibrary.org/obo/CLO_0001415 denotes 552
T57 6582-6586 http://purl.obolibrary.org/obo/CLO_0001106 denotes 1582
T58 6607-6610 http://purl.obolibrary.org/obo/CLO_0001002 denotes 162
T59 6657-6659 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T60 6695-6697 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T61 6736-6739 http://purl.obolibrary.org/obo/CLO_0001404 denotes 506
T62 7285-7292 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T63 7506-7507 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 7776-7779 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T65 8093-8094 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T66 8511-8512 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T67 8613-8614 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T68 8673-8674 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69 8889-8890 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T70 8908-8920 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T71 8954-8957 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T72 9442-9448 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T73 9461-9469 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activate
T74 9470-9471 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T75 9719-9720 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T76 9988-9996 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T77 10041-10042 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T78 10154-10155 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T79 10614-10615 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T80 10941-10942 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T81 11179-11180 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T82 11233-11243 http://purl.obolibrary.org/obo/OBI_0000245 denotes organizers
T83 11287-11288 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 11616-11622 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T85 11788-11794 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T86 11985-11987 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T87 12036-12038 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T88 12041-12042 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T89 12467-12473 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T90 12474-12479 http://www.ebi.ac.uk/efo/EFO_0000825 denotes valve
T91 12515-12521 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T92 12656-12662 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T93 12921-12927 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T94 12944-12950 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T95 13090-13096 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T96 13122-13128 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T97 13249-13255 http://www.ebi.ac.uk/efo/EFO_0000265 denotes Aortic
T98 13256-13261 http://www.ebi.ac.uk/efo/EFO_0000825 denotes valve
T99 13270-13276 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T100 13357-13363 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T101 13432-13437 http://www.ebi.ac.uk/efo/EFO_0000825 denotes valve
T102 13559-13565 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T103 13559-13565 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T104 13559-13565 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T105 13559-13565 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T106 13965-13970 http://www.ebi.ac.uk/efo/EFO_0000825 denotes valve
T107 14024-14029 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T108 14024-14029 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T109 14024-14029 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T110 14024-14029 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T111 14066-14071 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T112 14066-14071 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T113 14066-14071 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T114 14066-14071 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T115 14244-14249 http://www.ebi.ac.uk/efo/EFO_0000825 denotes valve
T116 14376-14382 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T117 14376-14382 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T118 14414-14420 http://purl.obolibrary.org/obo/OBI_0000968 denotes device
T119 14437-14442 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T120 14437-14442 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T121 14437-14442 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T122 14437-14442 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T123 14791-14792 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T124 15009-15010 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T125 15228-15229 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T126 15705-15715 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing is
T127 15855-15862 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T128 15945-15946 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T129 15994-15995 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T130 16050-16051 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 16418-16419 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 16456-16457 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T133 16491-16492 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T134 16827-16833 http://purl.obolibrary.org/obo/UBERON_0001456 denotes facing
T135 16880-16881 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T136 16892-16904 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T137 16947-16956 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T138 17049-17054 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T139 17350-17356 http://purl.obolibrary.org/obo/UBERON_0001456 denotes facing

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1996-2004 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T2 3138-3140 Chemical denotes CO http://purl.obolibrary.org/obo/CHEBI_17245
T3 3143-3149 Chemical denotes corona http://purl.obolibrary.org/obo/CHEBI_37409
T4 3151-3153 Chemical denotes VI http://purl.obolibrary.org/obo/CHEBI_75012
T5 8139-8153 Chemical denotes antiviral drug http://purl.obolibrary.org/obo/CHEBI_36044
T6 8139-8148 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T7 8149-8153 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T8 9062-9064 Chemical denotes LA http://purl.obolibrary.org/obo/CHEBI_17351|http://purl.obolibrary.org/obo/CHEBI_73527
T10 13346-13348 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T11 13697-13700 Chemical denotes LAD http://purl.obolibrary.org/obo/CHEBI_73524
T12 14241-14243 Chemical denotes AV http://purl.obolibrary.org/obo/CHEBI_73809
T13 14262-14264 Chemical denotes AV http://purl.obolibrary.org/obo/CHEBI_73809
T14 14320-14323 Chemical denotes LAD http://purl.obolibrary.org/obo/CHEBI_73524
T15 16332-16341 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
5 25-42 Species denotes novel coronavirus Tax:2697049
6 237-243 Species denotes people Tax:9606
7 462-481 Disease denotes infectious diseases MESH:D003141
18 632-640 Species denotes patients Tax:9606
19 655-699 Species denotes severe acute respiratory syndrome (SARS)-CoV Tax:694009
20 901-909 Species denotes patients Tax:9606
21 997-1007 Species denotes outpatient Tax:9606
22 546-570 Disease denotes coronavirus disease 2019 MESH:C000657245
23 572-582 Disease denotes COVID-2019 MESH:C000657245
24 641-649 Disease denotes infected MESH:D007239
25 1074-1082 Disease denotes COVID-19 MESH:C000657245
26 1148-1156 Disease denotes COVID-19 MESH:C000657245
27 1229-1250 Disease denotes COVID emergency rooms MESH:C000657245
30 1376-1384 Species denotes patients Tax:9606
31 1321-1329 Disease denotes COVID-19 MESH:C000657245
42 1810-1815 Species denotes human Tax:9606
43 1954-1962 Species denotes patients Tax:9606
44 2069-2077 Species denotes patients Tax:9606
45 2148-2156 Species denotes patients Tax:9606
46 2195-2203 Species denotes patients Tax:9606
47 1975-1983 Disease denotes COVID-19 MESH:C000657245
48 2060-2068 Disease denotes COVID-19 MESH:C000657245
49 2123-2131 Disease denotes infected MESH:D007239
50 2162-2184 Disease denotes cardiovascular disease MESH:D002318
51 2315-2323 Disease denotes COVID-19 MESH:C000657245
53 2548-2556 Disease denotes COVID-19 MESH:C000657245
58 2713-2726 Species denotes coronaviruses Tax:11118
59 2769-2775 Species denotes humans Tax:9606
60 2850-2854 Disease denotes cold MESH:D000067390
61 2999-3008 Disease denotes pneumonia MESH:D011014
67 3032-3042 Species denotes SARS-CoV-2 Tax:2697049
68 3060-3071 Species denotes coronavirus Tax:11118
69 3095-3101 Species denotes humans Tax:9606
70 3118-3126 Disease denotes COVID-19 MESH:C000657245
71 3128-3136 Disease denotes COVID-19 MESH:C000657245
76 3212-3222 Species denotes SARS-CoV-2 Tax:2697049
77 3452-3461 Disease denotes pneumonia MESH:D011014
78 3528-3536 Disease denotes COVID-19 MESH:C000657245
79 3594-3602 Disease denotes COVID-19 MESH:C000657245
84 3799-3809 Species denotes SARS-CoV-2 Tax:2697049
85 3819-3826 Species denotes patient Tax:9606
86 3949-3956 Species denotes patient Tax:9606
87 4020-4029 Disease denotes pneumonia MESH:D011014
91 4169-4180 Species denotes coronavirus Tax:11118
92 4148-4156 Disease denotes COVID-19 MESH:C000657245
93 4505-4513 Disease denotes COVID-19 MESH:C000657245
98 4814-4824 Species denotes SARS-CoV-2 Tax:2697049
99 4866-4874 Species denotes patients Tax:9606
100 4920-4926 Species denotes people Tax:9606
101 5131-5139 Species denotes patients Tax:9606
104 5441-5451 Species denotes SARS-CoV-2 Tax:2697049
105 5481-5487 Disease denotes Deaths MESH:D003643
107 5342-5374 Disease denotes dettaglioNotizieNuovoCoronavirus
109 6776-6809 Disease denotes severe acute respiratory syndrome MESH:D045169
114 7234-7244 Species denotes SARS-CoV-2 Tax:2697049
115 6843-6852 Disease denotes mortality MESH:D003643
116 6863-6871 Disease denotes COVID-19 MESH:C000657245
117 6920-6929 Disease denotes mortality MESH:D003643
119 7305-7313 Disease denotes SYMPTOMS MESH:D051271
128 7451-7461 Species denotes SARS-CoV-2 Tax:2697049
129 7494-7500 Species denotes people Tax:9606
130 7579-7588 Disease denotes pneumonia MESH:D011014
131 7636-7641 Disease denotes death MESH:D003643
132 7643-7651 Disease denotes Dyspnoea MESH:D004417
133 7653-7658 Disease denotes cough MESH:D003371
134 7686-7691 Disease denotes fever MESH:D005334
135 7746-7755 Disease denotes diarrhoea MESH:D003967
142 7807-7814 Species denotes persons Tax:9606
143 7829-7839 Species denotes SARS-CoV-2 Tax:2697049
144 7815-7823 Disease denotes infected MESH:D007239
145 7965-7972 Disease denotes obesity MESH:D009765
146 7974-7986 Disease denotes hypertension MESH:D006973
147 7991-8008 Disease denotes diabetes mellitus MESH:D003920
152 8111-8121 Species denotes SARS-CoV-2 Tax:2697049
153 8261-8269 Species denotes patients Tax:9606
154 8299-8307 Species denotes patients Tax:9606
155 8181-8190 Disease denotes infection MESH:D007239
157 8398-8406 Disease denotes COVID-19 MESH:C000657245
160 8792-8800 Species denotes Patients Tax:9606
161 8995-9010 Disease denotes Willis-Knighton MESH:D011218
163 9340-9347 Species denotes patient Tax:9606
167 9516-9524 Species denotes patients Tax:9606
168 9493-9498 Disease denotes COVID MESH:C000657245
169 9543-9551 Disease denotes COVID-19 MESH:C000657245
171 9662-9669 Species denotes patient Tax:9606
175 9768-9774 Disease denotes trauma MESH:D014947
176 9776-9782 Disease denotes stroke MESH:D020521
177 9901-9922 Disease denotes myocardial infarction MESH:D009203
179 10234-10242 Species denotes patients Tax:9606
181 10616-10659 Disease denotes COVID-free postoperative cardiovascular ICU MESH:D008569
185 11057-11065 Species denotes patients Tax:9606
186 10739-10763 Disease denotes coronavirus disease 2019 MESH:C000657245
187 10885-10909 Disease denotes coronavirus disease-2019 MESH:C000657245
192 11523-11531 Species denotes patients Tax:9606
193 11589-11597 Species denotes patients Tax:9606
194 11640-11650 Species denotes SARS-CoV-2 Tax:2697049
195 11761-11769 Species denotes patients Tax:9606
197 12134-12144 Species denotes SARS-CoV-2 Tax:2697049
203 12635-12643 Species denotes patients Tax:9606
204 12507-12535 Disease denotes balloon aortic valvuloplasty MESH:D054549
205 12629-12634 Disease denotes COVID MESH:C000657245
206 12656-12671 Disease denotes aortic stenosis MESH:D001024
207 12679-12700 Disease denotes ischaemic cardiopathy MESH:D007511
233 12994-13002 Species denotes patients Tax:9606
234 12915-12936 Disease denotes Acute aortic syndrome MESH:D000208
235 12973-12982 Disease denotes haematoma
236 13008-13012 Disease denotes coma MESH:D003128
237 13035-13041 Disease denotes stroke MESH:D020521
238 13090-13105 Disease denotes aortic aneurysm MESH:D001014
239 13122-13137 Disease denotes aortic aneurysm MESH:D001014
240 13173-13199 Disease denotes collagenopathy OR Aneurysm MESH:C535964
241 13236-13285 Disease denotes hypertension Aortic valve Severe aortic stenosis MESH:D001024
242 13305-13345 Disease denotes lipotimia OR angina OR dyspnoea NYHA III MESH:D000787
243 13357-13377 Disease denotes aortic regurgitation MESH:D001022
244 13383-13461 Disease denotes Pulmonary oedema Haemodynamic instability Mitral valve Severe mitral stenosis MESH:D008946
245 13467-13483 Disease denotes Pulmonary oedema MESH:D011654
246 13521-13541 Disease denotes mitral insufficiency MESH:D008944
247 13566-13581 Disease denotes chordal rupture MESH:D012421
248 13593-13669 Disease denotes pulmonary oedema Ischaemic cardiopathy Unstable angina Severe LMCA stenosis MESH:D011654
249 13675-13709 Disease denotes Subocclusive proximal LAD stenosis MESH:C535887
250 13727-13764 Disease denotes PCI Postinfarction ventricular septal MESH:D006345
251 13765-13799 Disease denotes cardiac rupture Acute endocarditis MESH:D006341
252 13965-13982 Disease denotes valve dysfunction MESH:D006349
253 14024-14079 Disease denotes Heart failure OR Haemodynamic instability Heart failure MESH:D006333
254 14105-14169 Disease denotes LVAD implantation Miscellaneous Cardiac tamponade Atrial myxoma MESH:D006331
255 14179-14194 Disease denotes cardiac tumours MESH:D006338
256 14201-14213 Disease denotes High embolic MESH:D004617
257 14241-14261 Disease denotes AV valve obstruction MESH:D054537
259 12897-12905 Disease denotes COVID-19 MESH:C000657245
262 14266-14282 Disease denotes atrioventricular MESH:D054537
263 14294-14318 Disease denotes coronavirus disease 2019 MESH:C000657245
265 14688-14693 Disease denotes COVID MESH:C000657245
267 15080-15090 Species denotes SARS-CoV-2 Tax:2697049
279 15105-15113 Species denotes Patients Tax:9606
280 15122-15132 Species denotes SARS-CoV-2 Tax:2697049
281 15499-15509 Species denotes SARS-CoV-2 Tax:2697049
282 15519-15527 Species denotes patients Tax:9606
283 15893-15900 Species denotes patient Tax:9606
284 15910-15920 Species denotes SARS-CoV-2 Tax:2697049
285 15239-15247 Disease denotes COVID-19 MESH:C000657245
286 15283-15291 Disease denotes COVID-19 MESH:C000657245
287 15408-15417 Disease denotes COVID-ICU MESH:C000657245
288 15627-15632 Disease denotes COVID MESH:C000657245
289 16006-16011 Disease denotes COVID MESH:C000657245
294 16028-16036 Species denotes Patients Tax:9606
295 16219-16236 Species denotes novel coronavirus Tax:2697049
296 16116-16125 Disease denotes infection MESH:D007239
297 16187-16192 Disease denotes COVID MESH:C000657245
301 16395-16403 Disease denotes COVID-19 MESH:C000657245
302 16642-16651 Disease denotes mortality MESH:D003643
303 16922-16930 Disease denotes COVID-19 MESH:C000657245

TEST0

Id Subject Object Predicate Lexical cue
32437514-152-157-8062 165-166 ["32309796"] denotes 1
32437514-190-195-8063 3200-3201 ["32309796"] denotes 1
32437514-112-117-8064 7426-7427 ["32150748"] denotes 5
32437514-122-127-8065 7552-7553 ["32075786"] denotes 6
32437514-189-194-8066 8070-8071 ["31986264"] denotes 7
32437514-238-243-8067 8788-8789 ["28722550"] denotes 9
32437514-115-121-8068 14903-14905 ["28886619"] denotes 10

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 7161-7167 http://purl.obolibrary.org/obo/GO_0007568 denotes ageing
T2 9670-9679 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T3 12157-12178 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T4 12165-12178 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T5 15796-15817 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T6 15804-15817 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T7 16784-16793 http://purl.obolibrary.org/obo/GO_0016032 denotes virulence
T8 16784-16793 http://purl.obolibrary.org/obo/GO_0009405 denotes virulence

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T2 0-12 Sentence denotes INTRODUCTION
T3 13-168 Sentence denotes The current novel coronavirus outbreak, which began in December 2019 in the Wuhan region in China, represents a massive challenge for the entire world [1].
T4 169-308 Sentence denotes In this era of globalization, illnesses, as well as information and people, travel much more quickly today than they did even 10 years ago.
T5 309-512 Sentence denotes Worldwide health systems are currently under great pressure, trying to tackle the emergency based on previous decennial experience in dealing with other infectious diseases such as an influenza epidemic.
T6 513-792 Sentence denotes By the end of February 2020, the coronavirus disease 2019 (COVID-2019) had spread in Northern Italy, with thousands of patients infected with severe acute respiratory syndrome (SARS)-CoV-2, thus requiring the Italian government to quickly introduce emergency quarantine measures.
T7 793-944 Sentence denotes Lombardy, an important productive region in Northern Italy, was one of the most affected, with thousands of patients who tested positive for the virus.
T8 945-1034 Sentence denotes Consequently, almost all elective medical activity (outpatient and surgical) was stopped.
T9 1035-1089 Sentence denotes Entire hospitals were transformed into COVID-19 units.
T10 1090-1137 Sentence denotes In-hospital dedicated pathways were identified.
T11 1138-1273 Sentence denotes Whole new COVID-19 intensive care units (ICUs) were created in a few days, as have new non-COVID emergency rooms to treat urgent cases.
T12 1274-1411 Sentence denotes The emergency situation in Italy caused by the COVID-19 pandemic has also changed the way of treating patients requiring cardiac surgery.
T13 1412-1641 Sentence denotes The Lombardy regional government recently introduced new rules on how to reorganize hospitals by creating 4 hubs for adult and 1 for paediatric cardiac surgery, which will handle all emergency/urgent cases (∼150–200 cases/month).
T14 1642-1799 Sentence denotes This situation has never happened before in the modern era and obviously represents a challenge in terms of rapidity and effectiveness of the actions needed.
T15 1800-2014 Sentence denotes As far as human resources are concerned, most of the cardiac surgeons not working in the hub centres have been part of multidisciplinary teams caring for patients affected by COVID-19 in internal medicine and ICUs.
T16 2015-2185 Sentence denotes Of course, being admitted to a hospital with COVID-19 patients significantly increases the risk of becoming infected, especially for patients with cardiovascular disease.
T17 2186-2261 Sentence denotes However, patients with cardiac emergencies/urgencies deserve to be treated.
T18 2262-2461 Sentence denotes So far, only a few papers have been published on the COVID-19 pandemic, and even fewer have been published on the challenges of restructuring the medical care system under these emergency conditions.
T19 2462-2682 Sentence denotes Herein, we briefly summarize how, for the first time in Europe since the start of the COVID-19 outbreak, the entire cardiac surgery system in the North Italian region of Lombardy was modified to deal with this emergency.
T20 2684-2698 Sentence denotes THE SARS-CoV-2
T21 2699-2776 Sentence denotes The family of coronaviruses is common across the world in animals and humans.
T22 2777-2855 Sentence denotes These viruses generally are transmitted by droplets and cause the common cold.
T23 2856-3009 Sentence denotes Occasionally they are responsible for more severe diseases like the Middle East respiratory syndrome and the SARS, both of which often lead to pneumonia.
T24 3010-3203 Sentence denotes The illness caused by SARS-CoV-2, a new strain of coronavirus not previously seen in humans, has been named COVID-19 (COVID-19: CO = corona; VI = virus; D = disease; 19 = year of outbreak) [1].
T25 3204-3347 Sentence denotes Because SARS-CoV-2 is a new virus, the lack of immunity in the population and the absence of an effective vaccine explain its worldwide spread.
T26 3348-3715 Sentence denotes On 31 December 2019, Chinese authorities notified the World Health Organization (WHO) of an outbreak of pneumonia in Wuhan City, which was later classified as a new disease (named COVID-19), whereas 1 month later the WHO declared the outbreak of COVID-19 a ‘Public Health Emergency of International Concern’, and finally designated it a pandemic on 11 March 2020 [2].
T27 3717-3757 Sentence denotes FROM THE CHINESE TO THE ITALIAN OUTBREAK
T28 3758-3827 Sentence denotes On 21 February 2020, Italy had its first SARS-CoV-2-positive patient.
T29 3828-3944 Sentence denotes He was a 38-year-old man with no comorbidities, who came in contact with a friend who had recently moved from China.
T30 3945-4051 Sentence denotes The patient, living in Codogno (a small town near Milan), developed severe pneumonia requiring intubation.
T31 4052-4085 Sentence denotes Then, the Italian outbreak began.
T32 4086-4215 Sentence denotes To date, Italy has been more seriously affected than China by COVID-19 in terms of coronavirus cases per 1 million of population.
T33 4216-4323 Sentence denotes The unexpected Italian outbreak may be explained by the recent expansion of airline connections with China.
T34 4324-4411 Sentence denotes On 8 March 2020, the Italian government announced the lockdown of the affected regions.
T35 4412-4553 Sentence denotes Two days, the quarantine was extended to the entire country (the first in the world), as new COVID-19 cases were detected across the country.
T36 4554-4745 Sentence denotes Emergency measures included social distancing; the suspension of community and sporting events; and the closure of commercial activities, restaurants, educational institutes and universities.
T37 4747-4759 Sentence denotes EPIDEMIOLOGY
T38 4760-4950 Sentence denotes By 31 March 2020, Italy had 77 635 cases positive for SARS-CoV-2; 15 729 recovered individuals and 12 428 patients killed by the virus, with a total of 105 792 people involved (Table 1) [3].
T39 4951-5140 Sentence denotes However, the data are changing every minute and, unfortunately, they are significantly underestimated due to false-negative testing results and the high number of paucisymptomatic patients.
T40 5141-5149 Sentence denotes Table 1:
T41 5151-5432 Sentence denotes Italian epidemiological situation updated on 31 March 2020 (Italian Ministry of Health data; see online version for current up-to-date data: http://www.salute.gov.it/portale/nuovocoronavirus/dettaglioNotizieNuovoCoronavirus.jsp?lingua=italiano&menu=notizie &p=dalministero&id=4648)
T42 5433-5520 Sentence denotes Region SARS-CoV-2 positive Discharged healed Deaths Total Naso-/oropharyngeal swab
T43 5521-5571 Sentence denotes Hospitalized with symptoms ICU Quarantine Total
T44 5572-5641 Sentence denotes Lombardy 11 883 1324 11 917 25 124 10 885 7199 43 208 114 640
T45 5642-5709 Sentence denotes Emilia Romagna 3765 353 6835 10 953 1477 1644 14 074 54 532
T46 5710-5764 Sentence denotes Veneto 1680 356 5814 7850 828 477 9155 106 238
T47 5765-5820 Sentence denotes Piedmont 3174 452 4456 8082 365 854 9301 27 658
T48 5821-5875 Sentence denotes Tuscany 1120 293 2813 4226 138 244 4608 33 165
T49 5876-5927 Sentence denotes Marche 946 169 2237 3352 21 452 3825 11 724
T50 5928-5982 Sentence denotes Liguria 1153 179 1176 2508 480 428 3416 10 376
T51 5983-6035 Sentence denotes Lazio 1127 173 1342 2642 291 162 3095 34 677
T52 6036-6089 Sentence denotes Campania 501 133 1237 1871 88 133 2092 14 403
T53 6090-6138 Sentence denotes Trento 354 80 955 1389 193 164 1746 6973
T54 6139-6189 Sentence denotes Apulia 609 105 940 1654 39 110 1803 14 073
T55 6190-6199 Sentence denotes Friuli V.
T56 6200-6202 Sentence denotes G.
T57 6204-6246 Sentence denotes 215 60 885 1160 320 113 1593 14 899
T58 6247-6295 Sentence denotes Sicily 503 72 917 1492 74 81 1647 15 634
T59 6296-6344 Sentence denotes Abruzzo 335 73 783 1191 95 115 1401 8758
T60 6345-6395 Sentence denotes Bolzano 249 62 831 1142 153 76 1371 11 275
T61 6396-6442 Sentence denotes Umbria 176 43 632 851 190 37 1078 8685
T62 6443-6489 Sentence denotes Sardinia 113 28 516 657 34 31 722 5257
T63 6490-6536 Sentence denotes Calabria 132 17 457 606 17 36 659 9327
T64 6537-6586 Sentence denotes Aosta Valley 91 26 435 552 20 56 628 1582
T65 6587-6632 Sentence denotes Basilicata 37 17 162 216 3 7 226 2043
T66 6633-6673 Sentence denotes Molise 29 8 80 117 18 9 144 1049
T67 6674-6743 Sentence denotes Total 28 192 4023 45 420 77 635 15 729 12 428 105 792 506 968
T68 6744-6810 Sentence denotes ICU: intensive care unit; SARS: severe acute respiratory syndrome.
T69 6811-7106 Sentence denotes Current evidence shows that the mortality rate from COVID-19 in Italy (∼10%) could be higher than the global mortality rate of 3.4% estimated by the WHO and significantly greater than the 0.1% from the seasonal influenza in the USA reported by the Centers for Disease Control and Prevention [4].
T70 7107-7293 Sentence denotes These alarming data may be partially explained by the ageing of the Italian population and the underestimated incidence of the SARS-CoV-2 due to restrictive indications for swab testing.
T71 7295-7313 Sentence denotes SIGNS AND SYMPTOMS
T72 7314-7429 Sentence denotes According to the US Centers for Disease Control and Prevention, the incubation period is between 2 and 14 days [5].
T73 7430-7642 Sentence denotes Early data show that SARS-CoV-2 could be asymptomatic or affect people with a mild illness similar to seasonal influenza [6] but that, in some cases pneumonia develops, with severe complications leading to death.
T74 7643-7772 Sentence denotes Dyspnoea, cough and general discomfort and fever are the most common symptoms, whereas haemoptysis and diarrhoea seem to be rare.
T75 7773-7880 Sentence denotes It has been reported that elderly persons infected with SARS-CoV-2 are at increased risk for complications.
T76 7881-8073 Sentence denotes Similar to the situation with seasonal influenza, underlying comorbidities (such as obesity, hypertension and diabetes mellitus) represent important risk factors for unfavourable outcomes [7].
T77 8074-8195 Sentence denotes Currently, neither a vaccine against SARS-CoV-2 nor any specific antiviral drug is available to defeat the infection [2].
T78 8196-8333 Sentence denotes Therefore, most therapies target symptoms and provide support to patients with complications, and most patients treat themselves at home.
T79 8335-8354 Sentence denotes HUB-AND-SPOKE MODEL
T80 8355-8549 Sentence denotes On 8 March 2020, in order to deal with the COVID-19 outbreak, the Lombardy regional government revised the entire regional healthcare system by introducing a temporary ‘hub and spoke’ model [8].
T81 8550-8791 Sentence denotes The hub-and-spoke system is an organizational model comprising a network of primary anchor centres (hubs), able to provide a wide spectrum of services, and secondary satellite establishments (spokes), which offer more limited assistance [9].
T82 8792-8868 Sentence denotes Patients in the spokes needing more intensive care are routed to their hubs.
T83 8869-8950 Sentence denotes This model provides a highly efficient organization and enhanced quality of care.
T84 8951-9189 Sentence denotes It has been used in several countries (i.e. Willis-Knighton Health System’s hub-and-spoke network, Shreveport, LA, USA) and even in rural areas with beneficial results (i.e. catheterization laboratories in the Tamil Nadu region of India).
T85 9190-9271 Sentence denotes However, some disadvantages include hub congestion and transportation challenges.
T86 9272-9329 Sentence denotes As defined by the Lombardy ordinance, hub centres should:
T87 9330-9460 Sentence denotes Guarantee patient access/hospitalization by providing multiple available medical teams (with at least 1 team on active duty 24/7).
T88 9461-9575 Sentence denotes Activate a ‘fast track’ for non-COVID emergency/urgent patients, thereby avoiding COVID-19 emergency room transit.
T89 9576-9649 Sentence denotes Welcome spoke teams in their respective hubs and encourage collaboration.
T90 9650-9718 Sentence denotes Ensure that patient transport is managed by the forwarding hospital.
T91 9719-9960 Sentence denotes A decision was made to apply this model to major trauma, stroke, emergencies/urgencies in neurosurgery, cardiovascular surgery and interventional cardiology (in particular for acute myocardial infarction and electrophysiological procedures).
T92 9961-10040 Sentence denotes An ordinary extracorporeal membrane oxygenation network was maintained as well.
T93 10041-10198 Sentence denotes A mean of 150–200 adult and 50 paediatric cardiac surgical procedures have been estimated per month in Lombardy, a region with almost 10 million inhabitants.
T94 10199-10332 Sentence denotes In contrast to our usual practice, patients from other regions are now treated in their own district because of transfer limitations.
T95 10333-10412 Sentence denotes Four adult and 1 paediatric cardiac surgery hubs have been identified (Fig. 1).
T96 10413-10660 Sentence denotes In the decision-making process, the following criteria were considered for the choice of the hub centres: the presence of dedicated 24/7 operating rooms (at least 3 simultaneously) and the presence of a COVID-free postoperative cardiovascular ICU.
T97 10661-10670 Sentence denotes Figure 1:
T98 10672-10773 Sentence denotes Lombardy emergency cardiac surgery hub-and-spoke system during the coronavirus disease 2019 epidemic.
T99 10774-10931 Sentence denotes This map shows the reorganization of the cardiac surgery system for emergency and urgent situations during the coronavirus disease-2019 outbreak in Lombardy:
T100 10932-11124 Sentence denotes 4 adult (A–D) hubs and 1 paediatric (E) hub have been identified; satellite spoke centres (in numbers) are asked to transfer patients needing emergency/urgent surgery to their respective hubs.
T101 11126-11175 Sentence denotes LOMBARDY CARDIAC SURGERY EMERGENCY REORGANIZATION
T102 11176-11326 Sentence denotes As a consequence of the ordinance, on 10 March 2020, the organizers of the cardiac surgery hub centres reached a consensus about the following issues:
T103 11327-11453 Sentence denotes Hub definitions for emergency, urgent and non-deferrable (surgery needed within 2 months) conditions (Table 2) were agreed on.
T104 11454-11575 Sentence denotes Naso- or oropharyngeal swabs must be performed preoperatively in all patients either in the spoke or in the hub hospital.
T105 11576-11877 Sentence denotes In addition, patients with symptoms who tested positive for the SARS-CoV-2 needing surgery within 2 months (so-called ‘non-deferrable’) will not be operated on whereas emergency/urgent patients with symptoms who tested positive will be operated on (if surgery is the only suitable therapeutic option).
T106 11878-11950 Sentence denotes The number of ICU beds available in each hub centre must be declared (S.
T107 11951-12040 Sentence denotes Raffaele, n = 14–20; Monzino, n = 11; Legnano, n = 8; Brescia, n = 4–6; total n = 37/45).
T108 12041-12206 Sentence denotes A hub centre must have or must be provided with laboratory facilities for rapid diagnosis of SARS-CoV-2 (i.e. using reverse transcription polymerase chain reaction).
T109 12207-12288 Sentence denotes Weekly video meetings among hub centres will be held to share up-to-date reports.
T110 12289-12424 Sentence denotes Hub-and-spoke units must cooperate, particularly as relates to the rotation of the surgical teams in case of exhausting working shifts.
T111 12425-12701 Sentence denotes Transcatheter options (i.e. transcatheter aortic valve implantation, percutaneous balloon aortic valvuloplasty, percutaneous coronary intervention) should be considered in non-deferrable/emergency/urgent COVID patients affected by aortic stenosis and/or ischaemic cardiopathy.
T112 12702-12801 Sentence denotes Considering the limited number of ICU beds, surgical triage must favour emergency and urgent cases.
T113 12802-12810 Sentence denotes Table 2:
T114 12812-12914 Sentence denotes Definitions of emergency/urgent cardiac surgery cases adopted in Lombardy during the COVID-19 outbreak
T115 12915-13079 Sentence denotes Acute aortic syndrome Acute aortic dissection/intramural haematoma (excluding patients with coma OR age >80 years with stroke and/or evident visceral malperfusion)
T116 13080-13111 Sentence denotes Ascending aortic aneurysm ≥6 cm
T117 13112-13150 Sentence denotes Ascending aortic aneurysm ≥5.5 cm AND:
T118 13151-13190 Sentence denotes Marfan syndrome/other collagenopathy OR
T119 13191-13222 Sentence denotes Aneurysm increase >5 mm/year OR
T120 13223-13248 Sentence denotes Uncontrolled hypertension
T121 13249-13349 Sentence denotes Aortic valve Severe aortic stenosis AND symptoms (i.e. lipotimia OR angina OR dyspnoea NYHA III/IV)
T122 13350-13382 Sentence denotes Severe aortic regurgitation AND:
T123 13383-13399 Sentence denotes Pulmonary oedema
T124 13400-13424 Sentence denotes Haemodynamic instability
T125 13425-13466 Sentence denotes Mitral valve Severe mitral stenosis AND:
T126 13467-13486 Sentence denotes Pulmonary oedema OR
T127 13487-13511 Sentence denotes Haemodynamic instability
T128 13512-13514 Sentence denotes 2.
T129 13515-13609 Sentence denotes Acute mitral insufficiency due to papillary muscle/chordal rupture leading to pulmonary oedema
T130 13610-13648 Sentence denotes Ischaemic cardiopathy Unstable angina
T131 13649-13674 Sentence denotes Severe LMCA stenosis ≥70%
T132 13675-13730 Sentence denotes Subocclusive proximal LAD stenosis not suitable for PCI
T133 13731-13780 Sentence denotes Postinfarction ventricular septal/cardiac rupture
T134 13781-13932 Sentence denotes Acute endocarditis Emergency or urgent cases (as defined by European Society of Cardiology/European Association of Cardio-Thoracic Surgery Guidelines)
T135 13933-14023 Sentence denotes Severe bioprosthetic/mechanical valve dysfunction Emergency or urgent cases resulting in:
T136 14024-14040 Sentence denotes Heart failure OR
T137 14041-14065 Sentence denotes Haemodynamic instability
T138 14066-14122 Sentence denotes Heart failure Non-deferrable need for LVAD implantation
T139 14123-14155 Sentence denotes Miscellaneous Cardiac tamponade
T140 14156-14200 Sentence denotes Atrial myxoma OR other cardiac tumours with:
T141 14201-14221 Sentence denotes High embolic risk OR
T142 14222-14261 Sentence denotes In the presence of AV valve obstruction
T143 14262-14427 Sentence denotes AV: atrioventricular; COVID-19: coronavirus disease 2019; LAD: left anterior descending; LMCA: left main coronary artery; LVAD: left ventricular assist device; NYHA:
T144 14428-14496 Sentence denotes New York Heart Association; PCI: percutaneous coronary intervention.
T145 14497-14539 Sentence denotes The following issues were also considered:
T146 14540-14640 Sentence denotes The length of hospital stay after cardiac surgery is longer than that after percutaneous procedures.
T147 14641-14787 Sentence denotes In addition, although hub centres have to have COVID-free wards, hospital congestion is likely to increase the risk of in-hospitals transmissions.
T148 14788-14907 Sentence denotes As a consequence, under these extraordinary circumstances, transcatheter options may be considered more liberally [10].
T149 14908-15104 Sentence denotes Whenever possible, the postoperative in-hospital stay and rehabilitation period should be reduced to a minimum, encouraging ‘early discharge’, thereby lowering the risk of SARS-CoV-2 transmission.
T150 15105-15424 Sentence denotes Patients who are SARS-CoV-2 positive and who require emergency/urgent/non-deferrable cardiac surgery have to be treated in a specific COVID-19 pathway, which comprises dedicated COVID-19 negative pressure operating rooms, with specific protocols for cleaning; the postoperative stay will be confined to COVID-ICU/wards.
T151 15425-15639 Sentence denotes Cardiovascular healthcare personnel directly involved in the treatment of SARS-CoV-2-positive patients are required to use specific protective equipment (i.e. FFP2/FFP3 masks), similar to those used in COVID wards.
T152 15640-16027 Sentence denotes In addition, in emergency situations in which the result of swab testing is not available at the moment of surgery (it usually takes some hours to complete reverse transcription polymerase chain reaction laboratory testing), it must be assumed that the patient could be SARS-CoV-2 positive; therefore, as a precaution, the operation will be performed in a dedicated COVID operating room.
T153 16028-16207 Sentence denotes Patients who have had a recent cardiac operation are at increased risk of acquiring the infection during the postoperative period despite the establishment of COVID-free pathways.
T154 16208-16369 Sentence denotes In case of novel coronavirus superinfection in the interval after cardiac surgery, aggressive ventilation support and early antiviral therapy should be provided.
T155 16371-16382 Sentence denotes CONCLUSIONS
T156 16383-16499 Sentence denotes The Italian COVID-19 emergency, on a scale never before seen, represents a tremendous burden for society as a whole.
T157 16500-16622 Sentence denotes The government quickly established quarantine measures, but the first positive effects will only be seen after some weeks.
T158 16623-16714 Sentence denotes Unfortunately, the mortality rate seems much higher than that reported for other countries.
T159 16715-16794 Sentence denotes Further investigations are necessary to clarify the reasons for such virulence.
T160 16795-17055 Sentence denotes The entire healthcare system is facing difficult challenges, but the introduction of a different organization model during the COVID-19 outbreak may be extremely helpful and should be able to satisfy all emergency needs, especially in the cardiovascular field.
T161 17056-17140 Sentence denotes The results of this new network will be determined only at the end of this pandemic.
T162 17141-17294 Sentence denotes By describing the Lombardy cardiac surgery reorganization model, we are sharing with the cardiovascular community our response to this amazing challenge.
T163 17295-17371 Sentence denotes We hope, by so doing, to be of help to other countries facing this pandemic.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 2162-2184 Phenotype denotes cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626
T2 2999-3008 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T3 3452-3461 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 4020-4029 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 7579-7588 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T6 7643-7651 Phenotype denotes Dyspnoea http://purl.obolibrary.org/obo/HP_0002094
T7 7653-7658 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T8 7686-7691 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T9 7730-7741 Phenotype denotes haemoptysis http://purl.obolibrary.org/obo/HP_0002105
T10 7746-7755 Phenotype denotes diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T11 7965-7972 Phenotype denotes obesity http://purl.obolibrary.org/obo/HP_0001513
T12 7974-7986 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T13 7991-8008 Phenotype denotes diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T14 9776-9782 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T15 9901-9922 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T16 12656-12671 Phenotype denotes aortic stenosis http://purl.obolibrary.org/obo/HP_0001650
T17 12944-12961 Phenotype denotes aortic dissection http://purl.obolibrary.org/obo/HP_0002647
T18 13008-13012 Phenotype denotes coma http://purl.obolibrary.org/obo/HP_0001259
T19 13035-13041 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T20 13080-13105 Phenotype denotes Ascending aortic aneurysm http://purl.obolibrary.org/obo/HP_0004970
T21 13112-13137 Phenotype denotes Ascending aortic aneurysm http://purl.obolibrary.org/obo/HP_0004970
T22 13191-13199 Phenotype denotes Aneurysm http://purl.obolibrary.org/obo/HP_0002617
T23 13236-13248 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T24 13270-13285 Phenotype denotes aortic stenosis http://purl.obolibrary.org/obo/HP_0001650
T25 13328-13336 Phenotype denotes dyspnoea http://purl.obolibrary.org/obo/HP_0002094
T26 13357-13377 Phenotype denotes aortic regurgitation http://purl.obolibrary.org/obo/HP_0001659
T27 13383-13399 Phenotype denotes Pulmonary oedema http://purl.obolibrary.org/obo/HP_0100598
T28 13446-13461 Phenotype denotes mitral stenosis http://purl.obolibrary.org/obo/HP_0001718
T29 13467-13483 Phenotype denotes Pulmonary oedema http://purl.obolibrary.org/obo/HP_0100598
T30 13521-13541 Phenotype denotes mitral insufficiency http://purl.obolibrary.org/obo/HP_0001653
T31 13593-13609 Phenotype denotes pulmonary oedema http://purl.obolibrary.org/obo/HP_0100598
T32 13787-13799 Phenotype denotes endocarditis http://purl.obolibrary.org/obo/HP_0100584
T33 14024-14037 Phenotype denotes Heart failure http://purl.obolibrary.org/obo/HP_0001635
T34 14066-14079 Phenotype denotes Heart failure http://purl.obolibrary.org/obo/HP_0001635

MyTest

Id Subject Object Predicate Lexical cue
32437514-32309796-28906075 165-166 32309796 denotes 1
32437514-32309796-28906076 3200-3201 32309796 denotes 1
32437514-32150748-28906077 7426-7427 32150748 denotes 5
32437514-32075786-28906078 7552-7553 32075786 denotes 6
32437514-31986264-28906079 8070-8071 31986264 denotes 7
32437514-28722550-28906080 8788-8789 28722550 denotes 9
32437514-28886619-28906081 14903-14905 28886619 denotes 10

0_colil

Id Subject Object Predicate Lexical cue
32437514-32309796-8062 165-166 32309796 denotes 1
32437514-32309796-8063 3200-3201 32309796 denotes 1
32437514-32150748-8064 7426-7427 32150748 denotes 5
32437514-32075786-8065 7552-7553 32075786 denotes 6
32437514-31986264-8066 8070-8071 31986264 denotes 7
32437514-28722550-8067 8788-8789 28722550 denotes 9
32437514-28886619-8068 14903-14905 28886619 denotes 10

2_test

Id Subject Object Predicate Lexical cue
32437514-32309796-28906075 165-166 32309796 denotes 1
32437514-32309796-28906076 3200-3201 32309796 denotes 1
32437514-32150748-28906077 7426-7427 32150748 denotes 5
32437514-32075786-28906078 7552-7553 32075786 denotes 6
32437514-31986264-28906079 8070-8071 31986264 denotes 7
32437514-28722550-28906080 8788-8789 28722550 denotes 9
32437514-28886619-28906081 14903-14905 28886619 denotes 10

testtesttest

Id Subject Object Predicate Lexical cue uberon_id
T2 326-333 Body_part denotes systems http://purl.obolibrary.org/obo/UBERON_0000467
T3 2421-2427 Body_part denotes system http://purl.obolibrary.org/obo/UBERON_0000467
T4 2594-2600 Body_part denotes system http://purl.obolibrary.org/obo/UBERON_0000467
T5 8489-8495 Body_part denotes system http://purl.obolibrary.org/obo/UBERON_0000467
T6 8568-8574 Body_part denotes system http://purl.obolibrary.org/obo/UBERON_0000467
T7 9988-9996 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T10 10436-10443 Body_part denotes process http://purl.obolibrary.org/obo/UBERON_0004529
T11 10721-10727 Body_part denotes system http://purl.obolibrary.org/obo/UBERON_0000467
T12 10831-10837 Body_part denotes system http://purl.obolibrary.org/obo/UBERON_0000467
T13 11233-11243 Body_part denotes organizers http://purl.obolibrary.org/obo/UBERON_0003062|http://purl.obolibrary.org/obo/UBERON_3010449|http://purl.obolibrary.org/obo/UBERON_3010457
T16 12467-12479 Body_part denotes aortic valve http://purl.obolibrary.org/obo/UBERON_0002137
T17 13249-13261 Body_part denotes Aortic valve http://purl.obolibrary.org/obo/UBERON_0002137
T18 13425-13437 Body_part denotes Mitral valve http://purl.obolibrary.org/obo/UBERON_0002135
T19 13549-13565 Body_part denotes papillary muscle http://purl.obolibrary.org/obo/UBERON_0002494
T20 13965-13970 Body_part denotes valve http://purl.obolibrary.org/obo/UBERON_0003978
T21 14024-14029 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948|http://purl.obolibrary.org/obo/UBERON_0007100|http://purl.obolibrary.org/obo/UBERON_0015228|http://purl.obolibrary.org/obo/UBERON_0015230
T25 14066-14071 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948|http://purl.obolibrary.org/obo/UBERON_0007100|http://purl.obolibrary.org/obo/UBERON_0015228|http://purl.obolibrary.org/obo/UBERON_0015230
T29 14241-14249 Body_part denotes AV valve http://purl.obolibrary.org/obo/UBERON_0002133
T30 14367-14382 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T31 14437-14442 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948|http://purl.obolibrary.org/obo/UBERON_0007100|http://purl.obolibrary.org/obo/UBERON_0015228|http://purl.obolibrary.org/obo/UBERON_0015230
T35 16420-16425 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T36 16817-16823 Body_part denotes system http://purl.obolibrary.org/obo/UBERON_0000467
T37 17049-17054 Body_part denotes field http://purl.obolibrary.org/obo/UBERON_0007688