PMC:7309518 / 1379-2077 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T8","span":{"begin":31,"end":43},"obj":"Body_part"},{"id":"T9","span":{"begin":48,"end":64},"obj":"Body_part"},{"id":"T10","span":{"begin":65,"end":76},"obj":"Body_part"},{"id":"T11","span":{"begin":218,"end":224},"obj":"Body_part"},{"id":"T12","span":{"begin":344,"end":353},"obj":"Body_part"},{"id":"T13","span":{"begin":680,"end":684},"obj":"Body_part"}],"attributes":[{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma65239"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma82780"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma32558"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma79876"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T2","span":{"begin":59,"end":64},"obj":"Body_part"},{"id":"T3","span":{"begin":344,"end":353},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0001021"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0002298"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T29","span":{"begin":14,"end":22},"obj":"Disease"},{"id":"T30","span":{"begin":149,"end":157},"obj":"Disease"},{"id":"T31","span":{"begin":269,"end":277},"obj":"Disease"},{"id":"T32","span":{"begin":288,"end":291},"obj":"Disease"},{"id":"T34","span":{"begin":354,"end":366},"obj":"Disease"},{"id":"T35","span":{"begin":368,"end":388},"obj":"Disease"}],"attributes":[{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0009722"},{"id":"A33","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0016098"},{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0019956"},{"id":"A35","pred":"mondo_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/MONDO_0003569"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T4","span":{"begin":48,"end":64},"obj":"http://purl.obolibrary.org/obo/UBERON_0001021"},{"id":"T5","span":{"begin":218,"end":224},"obj":"http://purl.obolibrary.org/obo/UBERON_0001630"},{"id":"T6","span":{"begin":218,"end":224},"obj":"http://purl.obolibrary.org/obo/UBERON_0005090"},{"id":"T7","span":{"begin":218,"end":224},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T8","span":{"begin":218,"end":224},"obj":"http://www.ebi.ac.uk/efo/EFO_0001949"},{"id":"T9","span":{"begin":678,"end":684},"obj":"http://purl.obolibrary.org/obo/CL_0000236"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T10","span":{"begin":31,"end":43},"obj":"Chemical"},{"id":"T11","span":{"begin":65,"end":76},"obj":"Chemical"},{"id":"T12","span":{"begin":101,"end":109},"obj":"Chemical"},{"id":"T13","span":{"begin":624,"end":632},"obj":"Chemical"},{"id":"T14","span":{"begin":634,"end":647},"obj":"Chemical"},{"id":"T15","span":{"begin":649,"end":661},"obj":"Chemical"}],"attributes":[{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_33563"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_16919"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_35341"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_62932"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_2948"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}

{"project":"LitCovid-PubTator","denotations":[{"id":"49","span":{"begin":101,"end":116},"obj":"Gene"},{"id":"52","span":{"begin":167,"end":175},"obj":"Species"},{"id":"53","span":{"begin":186,"end":194},"obj":"Species"},{"id":"56","span":{"begin":31,"end":43},"obj":"Chemical"},{"id":"57","span":{"begin":65,"end":76},"obj":"Chemical"},{"id":"58","span":{"begin":624,"end":632},"obj":"Chemical"},{"id":"59","span":{"begin":634,"end":647},"obj":"Chemical"},{"id":"60","span":{"begin":649,"end":661},"obj":"Chemical"},{"id":"71","span":{"begin":14,"end":22},"obj":"Disease"},{"id":"72","span":{"begin":149,"end":166},"obj":"Disease"},{"id":"73","span":{"begin":210,"end":233},"obj":"Disease"},{"id":"74","span":{"begin":269,"end":277},"obj":"Disease"},{"id":"75","span":{"begin":354,"end":366},"obj":"Disease"},{"id":"76","span":{"begin":368,"end":388},"obj":"Disease"},{"id":"77","span":{"begin":462,"end":483},"obj":"Disease"}],"attributes":[{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Gene:51727"},{"id":"A52","pred":"tao:has_database_id","subj":"52","obj":"Tax:9606"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"Tax:9606"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"MESH:D005732"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"MESH:D006017"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"MESH:D013256"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:D009173"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D001379"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"MESH:C000657245"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:C000657245"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"MESH:D018908"},{"id":"A74","pred":"tao:has_database_id","subj":"74","obj":"MESH:C000657245"},{"id":"A75","pred":"tao:has_database_id","subj":"75","obj":"MESH:D004660"},{"id":"A76","pred":"tao:has_database_id","subj":"76","obj":"MESH:D003389"},{"id":"A77","pred":"tao:has_database_id","subj":"77","obj":"MESH:D003711"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}

{"project":"LitCovid-sentences","denotations":[{"id":"T14","span":{"begin":92,"end":316},"obj":"Sentence"},{"id":"T15","span":{"begin":317,"end":557},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T12","span":{"begin":92,"end":116},"obj":"Phenotype"},{"id":"T13","span":{"begin":218,"end":233},"obj":"Phenotype"},{"id":"T14","span":{"begin":354,"end":366},"obj":"Phenotype"},{"id":"T15","span":{"begin":394,"end":420},"obj":"Phenotype"},{"id":"T16","span":{"begin":462,"end":475},"obj":"Phenotype"},{"id":"T17","span":{"begin":544,"end":556},"obj":"Phenotype"}],"attributes":[{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0003236"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0001324"},{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0002383"},{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0032070"},{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0011096"},{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0002960"}],"text":"ivity between COVID-19–bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (\u003e10,000) is reported in 10% of COVID-19–infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19–triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were a"}