PMC:7307149 / 6046-6357 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T41","span":{"begin":9,"end":12},"obj":"Body_part"},{"id":"T42","span":{"begin":70,"end":73},"obj":"Body_part"},{"id":"T43","span":{"begin":280,"end":283},"obj":"Body_part"}],"attributes":[{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma84079"}],"text":" a given HLA allele to produce an antiviral response, we assessed the HLA binding affinity of all possible 8-mers to 12-mers from the SARS-CoV-2 proteome (n = 48,395 unique peptides). We then removed from further consideration 16,138 peptides that were not predicted to enter the MHC class I antigen processing "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T46","span":{"begin":134,"end":142},"obj":"Disease"}],"attributes":[{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":" a given HLA allele to produce an antiviral response, we assessed the HLA binding affinity of all possible 8-mers to 12-mers from the SARS-CoV-2 proteome (n = 48,395 unique peptides). We then removed from further consideration 16,138 peptides that were not predicted to enter the MHC class I antigen processing "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T63","span":{"begin":1,"end":2},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T64","span":{"begin":173,"end":181},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T65","span":{"begin":234,"end":242},"obj":"http://purl.obolibrary.org/obo/PR_000018263"}],"text":" a given HLA allele to produce an antiviral response, we assessed the HLA binding affinity of all possible 8-mers to 12-mers from the SARS-CoV-2 proteome (n = 48,395 unique peptides). We then removed from further consideration 16,138 peptides that were not predicted to enter the MHC class I antigen processing "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T13","span":{"begin":34,"end":43},"obj":"Chemical"},{"id":"T14","span":{"begin":173,"end":181},"obj":"Chemical"},{"id":"T15","span":{"begin":234,"end":242},"obj":"Chemical"},{"id":"T16","span":{"begin":292,"end":299},"obj":"Chemical"}],"attributes":[{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"}],"text":" a given HLA allele to produce an antiviral response, we assessed the HLA binding affinity of all possible 8-mers to 12-mers from the SARS-CoV-2 proteome (n = 48,395 unique peptides). We then removed from further consideration 16,138 peptides that were not predicted to enter the MHC class I antigen processing "}

{"project":"LitCovid-PubTator","denotations":[{"id":"155","span":{"begin":280,"end":299},"obj":"Gene"},{"id":"158","span":{"begin":134,"end":144},"obj":"Species"}],"attributes":[{"id":"A155","pred":"tao:has_database_id","subj":"155","obj":"Gene:100507703"},{"id":"A158","pred":"tao:has_database_id","subj":"158","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" a given HLA allele to produce an antiviral response, we assessed the HLA binding affinity of all possible 8-mers to 12-mers from the SARS-CoV-2 proteome (n = 48,395 unique peptides). We then removed from further consideration 16,138 peptides that were not predicted to enter the MHC class I antigen processing "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T11","span":{"begin":34,"end":52},"obj":"http://purl.obolibrary.org/obo/GO_0051607"},{"id":"T12","span":{"begin":280,"end":283},"obj":"http://purl.obolibrary.org/obo/GO_0046776"},{"id":"T13","span":{"begin":292,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0019882"}],"text":" a given HLA allele to produce an antiviral response, we assessed the HLA binding affinity of all possible 8-mers to 12-mers from the SARS-CoV-2 proteome (n = 48,395 unique peptides). We then removed from further consideration 16,138 peptides that were not predicted to enter the MHC class I antigen processing "}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T1","span":{"begin":290,"end":299},"obj":"GlycoEpitope"}],"attributes":[{"id":"A1","pred":"glyco_epitope_db_id","subj":"T1","obj":"http://www.glycoepitope.jp/epitopes/EP0138"}],"text":" a given HLA allele to produce an antiviral response, we assessed the HLA binding affinity of all possible 8-mers to 12-mers from the SARS-CoV-2 proteome (n = 48,395 unique peptides). We then removed from further consideration 16,138 peptides that were not predicted to enter the MHC class I antigen processing "}