PMC:7305584 / 2668-3634
Annnotations
{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7305584","sourcedb":"PMC","sourceid":"7305584","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7305584","text":"It is reported that approximately half of the population has Circle of Willis (COW) variants [9–12]. On the other hand, cerebral aneurysms are not uncommon in patients with asymmetric COW variants, such as anterior communicating artery (AcomA) aneurysms in A1 aplasia, and posterior communicating artery (PcomA) aneurysms in fetal posterior cerebral artery (F-PCA) [13, 14]. Moreover, carotid flow contralateral to A1 aplasia, and ipsilateral to F-PCA, has been shown to be greater than those with a normal COW [15–18]. Total brain blood flow and distribution in different COW-types also had been proposed [16]. It had been shown that inflow boundary condition [3, 19], especially parent artery flow volume and the conjoint inflow ratio, affect the hemodynamic parameters of cerebral aneurysms. Therefore, adjustment of inflow boundary conditions for cerebral aneurysm analysis according to different COW types is important for obtaining reliable simulation results.","tracks":[{"project":"2_test","denotations":[{"id":"32563264-9530305-12762891","span":{"begin":94,"end":95},"obj":"9530305"},{"id":"32563264-30692833-12762891","span":{"begin":94,"end":95},"obj":"30692833"},{"id":"32563264-10835455-12762891","span":{"begin":94,"end":95},"obj":"10835455"},{"id":"32563264-20933644-12762892","span":{"begin":366,"end":368},"obj":"20933644"},{"id":"32563264-11990810-12762893","span":{"begin":370,"end":372},"obj":"11990810"},{"id":"32563264-15749975-12762894","span":{"begin":512,"end":514},"obj":"15749975"},{"id":"32563264-25564234-12762894","span":{"begin":512,"end":514},"obj":"25564234"},{"id":"32563264-16971634-12762894","span":{"begin":512,"end":514},"obj":"16971634"},{"id":"32563264-25388677-12762894","span":{"begin":512,"end":514},"obj":"25388677"},{"id":"32563264-25564234-12762895","span":{"begin":607,"end":609},"obj":"25564234"},{"id":"32563264-17110667-12762896","span":{"begin":662,"end":663},"obj":"17110667"},{"id":"32563264-17564178-12762897","span":{"begin":665,"end":667},"obj":"17564178"}],"attributes":[{"subj":"32563264-9530305-12762891","pred":"source","obj":"2_test"},{"subj":"32563264-30692833-12762891","pred":"source","obj":"2_test"},{"subj":"32563264-10835455-12762891","pred":"source","obj":"2_test"},{"subj":"32563264-20933644-12762892","pred":"source","obj":"2_test"},{"subj":"32563264-11990810-12762893","pred":"source","obj":"2_test"},{"subj":"32563264-15749975-12762894","pred":"source","obj":"2_test"},{"subj":"32563264-25564234-12762894","pred":"source","obj":"2_test"},{"subj":"32563264-16971634-12762894","pred":"source","obj":"2_test"},{"subj":"32563264-25388677-12762894","pred":"source","obj":"2_test"},{"subj":"32563264-25564234-12762895","pred":"source","obj":"2_test"},{"subj":"32563264-17110667-12762896","pred":"source","obj":"2_test"},{"subj":"32563264-17564178-12762897","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#9397ec","default":true}]}]}}