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PMC:7301188 / 8815-15849 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T105 5153-5169 GO:0050817 denotes hypercoagulating
T49 15-23 SP_7 denotes COVID-19
T50 79-90 NCBITaxon:11118 denotes coronavirus
T51 92-102 SP_7 denotes SARS-CoV-2
T52 118-126 SP_7 denotes COVID-19
T53 331-334 GO:0016265 denotes die
T54 373-381 SP_7 denotes COVID-19
T55 579-590 GO:0050817 denotes coagulation
T56 699-707 SP_7 denotes COVID-19
T57 841-849 UBERON:0010210 denotes thrombus
T58 874-878 UBERON:0002048 denotes lung
T59 880-885 UBERON:0000948 denotes heart
T60 887-893 UBERON:0002113 denotes kidney
T61 902-907 UBERON:0002107 denotes liver
T62 914-924 SP_7 denotes SARS-CoV-2
T63 955-986 PG_10;PR:000003622 denotes angiotensin-converting enzyme 2
T64 988-992 G_3;PG_10;PR:000003622 denotes ACE2
T65 1030-1037 CL:0000219;UBERON:0000344 denotes mucosal
T66 1038-1048 UBERON:0000483;CL:0000066 denotes epithelial
T67 1049-1054 CL:0000066 denotes cells
T68 1106-1110 PR:000017540 denotes PAMP
T69 1145-1158 UBERON:0002405 denotes immune system
T70 1164-1170 UBERON:0002405;GO:0006955 denotes immune
T71 1171-1179 GO:0006955 denotes response
T72 1206-1211 NCBITaxon:10239 denotes virus
T73 1236-1242 UBERON:0002405;GO:0006955 denotes immune
T74 1243-1251 GO:0006955 denotes response
T75 1326-1337 UBERON:0001986 denotes endothelial
T76 1360-1371 GO:0050817 denotes coagulation
T77 1397-1409 GO:0042730 denotes fibrinolytic
T78 1414-1429 GO:0050817 denotes anticoagulating
T79 1449-1459 GO:0007596 denotes thromboses
T80 1481-1487 UBERON:0002049 denotes system
T81 1523-1534 GO:0050817 denotes coagulation
T82 1605-1610 UBERON:0000062 denotes organ
T83 1683-1694 GO:0050817 denotes coagulation
T84 1768-1779 GO:0050817 denotes coagulation
T85 1842-1854 GO:0042730 denotes fibrinolytic
T86 1873-1879 CHEBI:5054;CHEBI:5054 denotes fibrin
T87 1973-1985 GO:0042730 denotes fibrinolysis
T88 2030-2042 GO:0042730 denotes fibrinolytic
T89 2059-2070 UBERON:0000467 denotes body system
T90 2121-2132 GO:0050817 denotes coagulating
T91 2216-2227 GO:0050817 denotes coagulation
T92 2256-2261 UBERON:0002107 denotes liver
T93 2313-2324 GO:0050817 denotes coagulation
T94 2329-2339 GO:0007596 denotes thrombosis
T95 2401-2411 GO:0007596 denotes thrombotic
T96 2511-2522 GO:0050817 denotes coagulating
T97 2640-2648 SP_7 denotes COVID-19
T98 2765-2773 SP_7 denotes COVID-19
T99 3063-3071 SP_7 denotes COVID-19
T100 3484-3492 SP_7 denotes COVID-19
T101 3551-3561 GO:0007596 denotes thrombosis
T102 3696-3707 GO:0050817 denotes coagulating
T103 5093-5104 GO:0050817 denotes coagulating
T104 5130-5138 SP_7 denotes COVID-19
T106 5206-5218 GO:0042730 denotes fibrinolysis
T107 5416-5427 GO:0050817 denotes coagulating
T108 5439-5451 GO:0042730 denotes fibrinolytic
T109 5494-5505 GO:0050817 denotes coagulating
T110 5569-5581 GO:0042730 denotes fibrinolytic
T111 5582-5593 GO:0009056 denotes degradation
T112 5849-5857 SP_7 denotes COVID-19
T113 6054-6063 UBERON:0002048 denotes pulmonary
T114 6296-6304 SP_7 denotes COVID-19
T115 6574-6582 SP_7 denotes COVID-19
T116 6607-6623 GO:0050817 denotes hypercoagulation
T117 6703-6714 GO:0050817 denotes coagulation
T118 6804-6814 GO:0007596 denotes thrombotic
T119 6898-6913 GO:0007596 denotes thromboembolism
T120 6935-6946 GO:0050817 denotes coagulation
T121 7007-7015 SP_7 denotes COVID-19
T8263 15-23 SP_7 denotes COVID-19
T53136 79-90 NCBITaxon:11118 denotes coronavirus
T94903 92-102 SP_7 denotes SARS-CoV-2
T39602 118-126 SP_7 denotes COVID-19
T44643 331-334 GO:0016265 denotes die
T20943 373-381 SP_7 denotes COVID-19
T42615 579-590 GO:0050817 denotes coagulation
T19824 699-707 SP_7 denotes COVID-19
T5414 841-849 UBERON:0010210 denotes thrombus
T28330 874-878 UBERON:0002048 denotes lung
T63655 880-885 UBERON:0000948 denotes heart
T80508 887-893 UBERON:0002113 denotes kidney
T8602 902-907 UBERON:0002107 denotes liver
T14036 914-924 SP_7 denotes SARS-CoV-2
T34847 955-986 PG_10;PR:000003622 denotes angiotensin-converting enzyme 2
T90610 988-992 G_3;PG_10;PR:000003622 denotes ACE2
T49124 1030-1037 CL:0000219;UBERON:0000344 denotes mucosal
T79134 1038-1048 UBERON:0000483;CL:0000066 denotes epithelial
T19986 1049-1054 CL:0000066 denotes cells
T31255 1106-1110 PR:000017540 denotes PAMP
T47825 1145-1158 UBERON:0002405 denotes immune system
T35483 1164-1170 UBERON:0002405;GO:0006955 denotes immune
T70637 1171-1179 GO:0006955 denotes response
T26218 1206-1211 NCBITaxon:10239 denotes virus
T6087 1236-1242 UBERON:0002405;GO:0006955 denotes immune
T65360 1243-1251 GO:0006955 denotes response
T64424 1326-1337 UBERON:0001986 denotes endothelial
T91538 1360-1371 GO:0050817 denotes coagulation
T61209 1397-1409 GO:0042730 denotes fibrinolytic
T1741 1414-1429 GO:0050817 denotes anticoagulating
T24928 1449-1459 GO:0007596 denotes thromboses
T35188 1481-1487 UBERON:0002049 denotes system
T27616 1523-1534 GO:0050817 denotes coagulation
T2954 1605-1610 UBERON:0000062 denotes organ
T2895 1683-1694 GO:0050817 denotes coagulation
T22399 1768-1779 GO:0050817 denotes coagulation
T47724 1842-1854 GO:0042730 denotes fibrinolytic
T1952 1873-1879 CHEBI:5054;CHEBI:5054 denotes fibrin
T28487 1973-1985 GO:0042730 denotes fibrinolysis
T99683 2030-2042 GO:0042730 denotes fibrinolytic
T19894 2059-2070 UBERON:0000467 denotes body system
T4998 2121-2132 GO:0050817 denotes coagulating
T26797 2216-2227 GO:0050817 denotes coagulation
T55920 2256-2261 UBERON:0002107 denotes liver
T66394 2313-2324 GO:0050817 denotes coagulation
T40464 2329-2339 GO:0007596 denotes thrombosis
T39548 2401-2411 GO:0007596 denotes thrombotic
T18045 2511-2522 GO:0050817 denotes coagulating
T33523 2640-2648 SP_7 denotes COVID-19
T50961 2765-2773 SP_7 denotes COVID-19
T72448 3063-3071 SP_7 denotes COVID-19
T30894 3484-3492 SP_7 denotes COVID-19
T65826 3551-3561 GO:0007596 denotes thrombosis
T92159 3696-3707 GO:0050817 denotes coagulating
T34057 5093-5104 GO:0050817 denotes coagulating
T54071 5130-5138 SP_7 denotes COVID-19
T87943 5153-5169 GO:0050817 denotes hypercoagulating
T67612 5206-5218 GO:0042730 denotes fibrinolysis
T83300 5416-5427 GO:0050817 denotes coagulating
T52640 5439-5451 GO:0042730 denotes fibrinolytic
T7105 5494-5505 GO:0050817 denotes coagulating
T7588 5569-5581 GO:0042730 denotes fibrinolytic
T28739 5582-5593 GO:0009056 denotes degradation
T54972 5849-5857 SP_7 denotes COVID-19
T47511 6054-6063 UBERON:0002048 denotes pulmonary
T68084 6296-6304 SP_7 denotes COVID-19
T9570 6574-6582 SP_7 denotes COVID-19
T3591 6607-6623 GO:0050817 denotes hypercoagulation
T41062 6703-6714 GO:0050817 denotes coagulation
T74771 6804-6814 GO:0007596 denotes thrombotic
T98909 6898-6913 GO:0007596 denotes thromboembolism
T54127 6935-6946 GO:0050817 denotes coagulation
T84163 7007-7015 SP_7 denotes COVID-19

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T8 874-878 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T9 880-885 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T10 887-893 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T11 902-907 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T12 938-942 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T13 1038-1054 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T14 1049-1054 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T15 1145-1158 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T16 1266-1274 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T17 1295-1303 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T18 1605-1610 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T19 1993-1997 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T20 2059-2063 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T21 2203-2210 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T22 2256-2261 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T7 874-878 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 880-885 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T9 887-893 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T10 902-907 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T11 1145-1158 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T12 1605-1610 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T13 2256-2261 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
231 79-90 Species denotes coronavirus Tax:11118
232 92-102 Species denotes SARS-CoV-2 Tax:2697049
233 188-196 Species denotes patients Tax:9606
234 290-298 Species denotes patients Tax:9606
235 553-561 Species denotes patients Tax:9606
236 15-23 Disease denotes COVID-19 MESH:C000657245
237 36-54 Disease denotes infectious disease MESH:D003141
238 118-126 Disease denotes COVID-19 MESH:C000657245
239 139-144 Disease denotes fever MESH:D005334
240 219-226 Disease denotes dyspnea MESH:D004417
241 314-326 Disease denotes septic shock MESH:D012772
242 373-381 Disease denotes COVID-19 MESH:C000657245
243 579-602 Disease denotes coagulation dysfunction MESH:D001778
244 699-707 Disease denotes COVID-19 MESH:C000657245
245 841-849 Disease denotes thrombus MESH:D013927
256 955-986 Gene denotes angiotensin-converting enzyme 2 Gene:59272
257 988-992 Gene denotes ACE2 Gene:59272
258 914-924 Species denotes SARS-CoV-2 Tax:2697049
259 1317-1344 Disease denotes vascular endothelial damage MESH:D057772
260 1439-1459 Disease denotes Excessive thromboses MESH:D013927
261 1496-1534 Disease denotes disseminated intravascular coagulation MESH:D004211
262 1536-1539 Disease denotes DIC MESH:D004211
263 1596-1631 Disease denotes multiple organ dysfunction syndrome MESH:D009102
264 1683-1706 Disease denotes coagulation dysfunction MESH:D001778
265 1732-1741 Disease denotes mortality MESH:D003643
275 2355-2357 Gene denotes Fg Gene:2244
276 2440-2442 Gene denotes Fg Gene:2244
277 2195-2197 Gene denotes Fg Gene:2244
278 1817-1819 Gene denotes Fg Gene:2244
279 2190-2193 Disease denotes DIC MESH:D004211
280 2329-2339 Disease denotes thrombosis MESH:D013927
281 2401-2420 Disease denotes thrombotic diseases MESH:D013927
282 2511-2534 Disease denotes coagulating dysfunction MESH:D001778
283 2640-2648 Disease denotes COVID-19 MESH:C000657245
304 3161-3163 Gene denotes Fg Gene:2244
305 3353-3355 Gene denotes Fg Gene:2244
306 3111-3113 Gene denotes Fg Gene:2244
307 2695-2697 Gene denotes Fg Gene:2244
308 2810-2818 Species denotes patients Tax:9606
309 2915-2923 Species denotes patients Tax:9606
310 3072-3080 Species denotes patients Tax:9606
311 3221-3229 Species denotes patients Tax:9606
312 3265-3273 Species denotes patients Tax:9606
313 3409-3417 Species denotes patients Tax:9606
314 3428-3436 Species denotes patients Tax:9606
315 3493-3501 Species denotes patients Tax:9606
316 3521-3529 Species denotes patients Tax:9606
317 2765-2773 Disease denotes COVID-19 MESH:C000657245
318 2900-2914 Disease denotes critically ill MESH:D016638
319 3063-3071 Disease denotes COVID-19 MESH:C000657245
320 3206-3220 Disease denotes critically ill MESH:D016638
321 3394-3408 Disease denotes critically ill MESH:D016638
322 3484-3492 Disease denotes COVID-19 MESH:C000657245
323 3551-3561 Disease denotes thrombosis MESH:D013927
329 3840-3848 Species denotes patients Tax:9606
330 4117-4125 Species denotes patients Tax:9606
331 4277-4285 Species denotes patients Tax:9606
332 4334-4342 Species denotes patients Tax:9606
333 4460-4468 Species denotes patients Tax:9606
340 4995-4997 Gene denotes Fg Gene:2244
341 5116-5124 Species denotes patients Tax:9606
342 5272-5280 Species denotes patients Tax:9606
343 5370-5378 Species denotes patients Tax:9606
344 5668-5676 Species denotes patients Tax:9606
345 5130-5138 Disease denotes COVID-19 MESH:C000657245
348 5849-5857 Disease denotes COVID-19 MESH:C000657245
349 6054-6072 Disease denotes pulmonary embolism MESH:D011655
351 6296-6304 Disease denotes COVID-19 MESH:C000657245
363 6560-6568 Species denotes patients Tax:9606
364 7025-7033 Species denotes patients Tax:9606
365 6521-6537 Disease denotes hypercoagulation MESH:D019851
366 6574-6582 Disease denotes COVID-19 MESH:C000657245
367 6607-6623 Disease denotes hypercoagulation MESH:D019851
368 6804-6828 Disease denotes thrombotic complications MESH:D013927
369 6898-6913 Disease denotes thromboembolism MESH:D013923
370 6918-6921 Disease denotes DIC MESH:D004211
371 6935-6955 Disease denotes coagulation disorder MESH:D001778
372 6994-7003 Disease denotes mortality MESH:D003643
373 7007-7024 Disease denotes COVID-19-infected MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T70 15-23 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T71 36-54 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T72 92-100 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T73 118-126 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T74 373-381 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T75 699-707 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T76 841-849 Disease denotes thrombus http://purl.obolibrary.org/obo/MONDO_0000831
T77 914-922 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 1449-1459 Disease denotes thromboses http://purl.obolibrary.org/obo/MONDO_0000831
T79 1496-1540 Disease denotes disseminated intravascular coagulation (DIC) http://purl.obolibrary.org/obo/MONDO_0001243
T80 1596-1631 Disease denotes multiple organ dysfunction syndrome http://purl.obolibrary.org/obo/MONDO_0043726
T81 1799-1801 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T83 1821-1823 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T85 1907-1909 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T87 2329-2339 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T88 2401-2420 Disease denotes thrombotic diseases http://purl.obolibrary.org/obo/MONDO_0000831
T89 2422-2424 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T91 2640-2648 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 2688-2690 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T94 2765-2773 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 2796-2798 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T97 2842-2844 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T99 3063-3071 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T100 3346-3348 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T102 3484-3492 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T103 3551-3561 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T104 3748-3750 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T106 3879-3881 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T108 3950-3952 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T110 4063-4065 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T112 4140-4142 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T114 4495-4497 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T116 5130-5138 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T117 5554-5556 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T119 5849-5857 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 5889-5891 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T122 6002-6004 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T124 6054-6072 Disease denotes pulmonary embolism http://purl.obolibrary.org/obo/MONDO_0005279
T125 6296-6304 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T126 6574-6582 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T127 6734-6736 Disease denotes DD http://purl.obolibrary.org/obo/MONDO_0009107|http://purl.obolibrary.org/obo/MONDO_0015613
T129 6935-6955 Disease denotes coagulation disorder http://purl.obolibrary.org/obo/MONDO_0001531
T130 7007-7015 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T71 65-66 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 164-165 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 874-878 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T74 874-878 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T75 880-885 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T76 880-885 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T77 880-885 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T78 880-885 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T79 887-893 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T80 887-893 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T81 887-893 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T82 902-907 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T83 902-907 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T84 1038-1048 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T85 1049-1054 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T86 1145-1158 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T87 1183-1192 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T88 1206-1211 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T89 1264-1265 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 1285-1286 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91 1346-1355 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T92 1605-1610 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T93 1633-1635 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T94 1934-1935 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 2043-2051 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T96 2201-2202 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 2256-2261 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T98 2256-2261 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T99 2388-2389 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 2574-2585 http://purl.obolibrary.org/obo/CLO_0009985 denotes was focused
T101 2788-2792 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T102 3275-3277 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T103 3536-3537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T104 3662-3663 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 3863-3865 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T106 3895-3899 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T107 3923-3925 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T108 4031-4036 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T109 4210-4214 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T110 4377-4382 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T111 4402-4404 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T112 4782-4786 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T113 5192-5202 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T114 5348-5353 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T115 5782-5785 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T116 5803-5804 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T117 6198-6199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T118 6368-6369 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T49 955-966 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T50 1536-1539 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092
T52 1799-1801 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T53 1803-1805 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T54 1821-1823 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T55 1907-1909 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T56 2080-2082 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T57 2190-2193 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092
T59 2203-2210 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T60 2374-2383 Chemical denotes indicator http://purl.obolibrary.org/obo/CHEBI_47867
T61 2422-2424 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T62 2426-2428 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T63 2688-2690 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T64 2796-2798 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T65 2842-2844 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T66 3346-3348 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T67 3748-3750 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T68 3752-3754 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T69 3879-3881 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T70 3950-3952 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T71 4063-4065 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T72 4140-4142 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T73 4218-4220 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T74 4374-4376 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T75 4495-4497 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T76 4502-4504 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T77 4770-4772 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T78 4846-4848 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T79 4947-4949 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T80 5235-5237 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T81 5554-5556 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T82 5889-5891 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T83 6002-6004 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T84 6126-6129 Chemical denotes CTA http://purl.obolibrary.org/obo/CHEBI_17217
T85 6250-6255 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T86 6423-6428 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T87 6734-6736 Chemical denotes DD http://purl.obolibrary.org/obo/CHEBI_73446
T88 6741-6743 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T89 6918-6921 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T8 579-590 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T9 1164-1179 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T10 1236-1251 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T11 1346-1371 http://purl.obolibrary.org/obo/GO_0050820 denotes activates the coagulation
T12 1360-1371 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T13 1523-1534 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T14 1683-1694 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T15 1768-1779 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T16 1973-1985 http://purl.obolibrary.org/obo/GO_0042730 denotes fibrinolysis
T17 2216-2227 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T18 2313-2324 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T19 5192-5218 http://purl.obolibrary.org/obo/GO_0051919 denotes activation of fibrinolysis
T20 5206-5218 http://purl.obolibrary.org/obo/GO_0042730 denotes fibrinolysis
T21 5582-5593 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T22 6703-6714 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T23 6935-6946 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T94 0-2 Sentence denotes 4.
T95 3-14 Sentence denotes Conclusions
T96 15-104 Sentence denotes COVID-19 is an acute infectious disease caused by a new type of coronavirus (SARS-CoV-2).
T97 105-182 Sentence denotes The onset of COVID-19 presents as fever, mild or sever, in a few cases [4–6].
T98 183-227 Sentence denotes Some patients may gradually develop dyspnea.
T99 228-342 Sentence denotes However, in severe cases, the disease progresses rapidly, and patients develop severe septic shock and die [7–10].
T100 343-481 Sentence denotes The severity and prognosis of COVID-19 are complicated by the diversity of symptoms, radiological manifestations, and disease progression.
T101 482-610 Sentence denotes It is particularly noteworthy that some severe, critical, and deceased patients have significant coagulation dysfunction [1, 4].
T102 611-908 Sentence denotes The pathological changes of the disease have been added into the seventh edition of the COVID-19 Treatment Plan issued by the National Health Commission of China, in which both autopsy and histopathologic examinations demonstrate thrombus or microthrombus in the lung, heart, kidney, and/or liver.
T103 909-1212 Sentence denotes Upon SARS-CoV-2 entering the body through the angiotensin-converting enzyme 2 (ACE2) receptor adsorbed on the surface of mucosal epithelial cells [7, 8], its pathogen-associated molecular pattern (PAMP) can be quickly recognized by the immune system, and immune response is activated to clear the virus.
T104 1213-1281 Sentence denotes However, overactivated immune response could cause a cytokine storm.
T105 1282-1438 Sentence denotes As a result, cytokine storm causes vascular endothelial damage, activates the coagulation system, and inhibits the fibrinolytic and anticoagulating systems.
T106 1439-1637 Sentence denotes Excessive thromboses in the microvascular system lead to disseminated intravascular coagulation (DIC) and, ultimately, microcirculatory disorder and serious multiple organ dysfunction syndrome [11].
T107 1638-1742 Sentence denotes Therefore, early detection and correction of coagulation dysfunction could effectively reduce mortality.
T108 1743-1820 Sentence denotes Commonly used laboratory coagulation indicators include DD, PT, APTT, and Fg.
T109 1821-2079 Sentence denotes DD is the product of fibrinolytic solubilization of fibrin, and the elevated level of DD indicates that there is a hypercoagulating state and secondary fibrinolysis in the body, which can be seen in increased fibrinolytic activity of the body system [12–15].
T110 2080-2194 Sentence denotes PT and APTT are exogenous and endogenous coagulating system factors, which can be used for early diagnosis of DIC.
T111 2195-2340 Sentence denotes Fg is a protein with coagulation function synthesized by the liver, which is an important substance in the process of coagulation and thrombosis.
T112 2341-2421 Sentence denotes High level of Fg is an important indicator for a variety of thrombotic diseases.
T113 2422-2535 Sentence denotes DD, PT, APTT, and Fg can be used as sensitive indicators to reflect different degrees of coagulating dysfunction.
T114 2536-2649 Sentence denotes Therefore, in this article, the study was focused on if these indicators are related to the severity of COVID-19.
T115 2650-2774 Sentence denotes The results of this study showed that DD and Fg could be used as new indicators for the clinical classification of COVID-19.
T116 2775-2889 Sentence denotes In the first test of DD, 50 of 115 patients had abnormal levels of DD (>0.55 mg/L), accounting for 43.5% (50/115).
T117 2890-3040 Sentence denotes Of the 28 critically ill patients, 17 were >0.55 mg/L, accounting for 60.7%. (17/25), and 14 cases had two times more than the normal reference value.
T118 3041-3114 Sentence denotes 70.4% (81/115) of the COVID-19 patients had abnormal concentration of Fg.
T119 3115-3292 Sentence denotes Additionally, it is noticed that the level of Fg was significantly increased in severe and critically ill patients, with 70.3% of severe and critical patients (52/74) >4.00 g/L.
T120 3293-3612 Sentence denotes The results of the study indicate that the levels of DD and Fg significantly increased in severe and critically ill patients, and some patients deteriorated during treatment, suggesting that COVID-19 patients, especially severe patients, have a high risk of thrombosis, which is consistent with previous reports [1, 4].
T121 3613-3826 Sentence denotes In addition, the results of this study also show a significant correlation between coagulating factors and disease outcome, suggesting DD, PT, and APTT could serve as diagnostic indicators for disease progression.
T122 3827-4006 Sentence denotes Among the 23 patients who deceased, 18 had abnormal DD in the first test, accounting for 78.3% (18/23), among which 12 had DD level two times more than the normal reference value.
T123 4007-4084 Sentence denotes In the second and third tests, 8 exacerbating cases had DD level > 1.10 mg/L.
T124 4085-4196 Sentence denotes Additionally, among 23 deceased patients, 21 cases had DD level two times more than the normal reference value.
T125 4197-4343 Sentence denotes In the first test of PT, there were two abnormalities (15 sec) in 8 aggravating patients whereas 5 abnormalities (15 sec) in 23 deceased patients.
T126 4344-4469 Sentence denotes While in the second and third PT tests, there were 10 and 18 abnormalities (> 15 sec), respectively, in 23 deceased patients.
T127 4470-4573 Sentence denotes The gradually increasing DD and PT levels suggest the significant correlation with disease progression.
T128 4574-4751 Sentence denotes Using discharged and deceased cases as the basis of positive division, the ROC curve analyses showed the areas under the curve (AUCs) were 0.742, 0.818, and 0.851, respectively.
T129 4752-4895 Sentence denotes The third time of PT and APTT test had AUCs at 0.937 and 0.856, respectively, indicating that PT and APTT had great value in disease prognosis.
T130 4896-5219 Sentence denotes Based on the study results, the levels of D-dimer, PT, and APTT were significantly higher, whereas Fg in deceased cases was significantly lower than those in survival cases, suggesting the dynamic coagulating process in patients with COVID-19 is likely the hypercoagulating state followed by the activation of fibrinolysis.
T131 5220-5514 Sentence denotes In this study, PT and APTT prolonged in 23 deceased patients, and the prolongation was more significant in the second and third tests, indicating the patients were in the transition from the high coagulating state into fibrinolytic state due to the excessive consumption of coagulating factors.
T132 5515-5770 Sentence denotes Additionally, the study results showed DD, one of the fibrinolytic degradation products, gradually increased throughout the disease, indicating that the patients were possibly in hyperfibrinolytic state, which is consistent with Chen et al.'s report [16].
T133 5771-5858 Sentence denotes CT imaging has been regarded as a valuable tool in diagnosis and prognosis of COVID-19.
T134 5859-5964 Sentence denotes The study results showed that DD was correlated with CT imaging in predicting the progression of disease.
T135 5965-6131 Sentence denotes Specifically, the increased level of DD suggests hypercoagulating state and the possible pulmonary embolism, which could be further confirmed by CT angiography (CTA).
T136 6132-6314 Sentence denotes One limitation of this study exists on that it was carried out in a single medical center with absence of the control group design due to the emergent situation of COVID-19 breakout.
T137 6315-6467 Sentence denotes In the future, the researchers should integrate with a few medical centers in the area and draw the control group to boost the reliability of the study.
T138 6468-6602 Sentence denotes In conclusion, the results of this study showed that hypercoagulation was likely present in patients with COVID-19 at the early stage.
T139 6603-6687 Sentence denotes And hypercoagulation is closely related to disease progression and clinical outcome.
T140 6688-6829 Sentence denotes Therefore, the coagulation indicators such as DD and PT should be monitored as early as possible in order to detect thrombotic complications.
T141 6830-7034 Sentence denotes It is imperative to take preventive treatment to reduce the risk of thromboembolism and DIC secondary to coagulation disorder, thereby decreasing the morbidity and mortality of COVID-19-infected patients.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T11 139-144 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T12 219-226 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T13 321-326 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T14 1266-1280 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T15 1295-1309 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T16 1496-1534 Phenotype denotes disseminated intravascular coagulation http://purl.obolibrary.org/obo/HP_0005521
T17 1536-1539 Phenotype denotes DIC http://purl.obolibrary.org/obo/HP_0005521
T18 2190-2193 Phenotype denotes DIC http://purl.obolibrary.org/obo/HP_0005521
T19 6054-6072 Phenotype denotes pulmonary embolism http://purl.obolibrary.org/obo/HP_0002204
T20 6898-6913 Phenotype denotes thromboembolism http://purl.obolibrary.org/obo/HP_0001907
T21 6918-6921 Phenotype denotes DIC http://purl.obolibrary.org/obo/HP_0005521

2_test

Id Subject Object Predicate Lexical cue
32596339-32073213-7053678 177-178 32073213 denotes 4
32596339-31986264-7053678 177-178 31986264 denotes 4
32596339-31996437-7053679 336-337 31996437 denotes 7
32596339-18424768-7053679 336-337 18424768 denotes 7
32596339-32109012-7053679 336-337 32109012 denotes 7
32596339-32048815-7053679 336-337 32048815 denotes 7
32596339-32109013-7053680 604-605 32109013 denotes 1
32596339-32073213-7053681 607-608 32073213 denotes 4
32596339-31996437-7053682 1056-1057 31996437 denotes 7
32596339-18424768-7053683 1059-1060 18424768 denotes 8
32596339-12490963-7053684 1633-1635 12490963 denotes 11
32596339-26450781-7053685 2072-2074 26450781 denotes 12
32596339-25617378-7053685 2072-2074 25617378 denotes 12
32596339-30318940-7053685 2072-2074 30318940 denotes 12
32596339-32052846-7053685 2072-2074 32052846 denotes 12
32596339-32109013-7053686 3606-3607 32109013 denotes 1
32596339-32073213-7053687 3609-3610 32073213 denotes 4
32596339-32007143-7053688 5766-5768 32007143 denotes 16