PMC:7299399 / 7584-8122 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T31","span":{"begin":150,"end":162},"obj":"Body_part"},{"id":"T32","span":{"begin":150,"end":154},"obj":"Body_part"},{"id":"T33","span":{"begin":178,"end":184},"obj":"Body_part"},{"id":"T34","span":{"begin":315,"end":324},"obj":"Body_part"},{"id":"T35","span":{"begin":347,"end":356},"obj":"Body_part"},{"id":"T36","span":{"begin":401,"end":407},"obj":"Body_part"},{"id":"T37","span":{"begin":424,"end":431},"obj":"Body_part"},{"id":"T38","span":{"begin":459,"end":462},"obj":"Body_part"},{"id":"T39","span":{"begin":467,"end":474},"obj":"Body_part"}],"attributes":[{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma67653"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma82764"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma67180"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma67180"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A37","pred":"fma_id","subj":"T37","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A38","pred":"fma_id","subj":"T38","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A39","pred":"fma_id","subj":"T39","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"SARS-CoV-2 viral life cycle and potential targets for nanomaterials. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptors on the host cell surface. Transmembrane serine protease 2 (TMPRSS2) facilitates cellular entry through protease activity. Later, viral particles are internalized and enter into endosomes. Due to the low pH of endosomes, viral particles are uncoated and the viral genome is released for protein synthesis. Following viral RNA and protein synthesis, new infectious particles are assembled and released."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T41","span":{"begin":0,"end":8},"obj":"Disease"},{"id":"T42","span":{"begin":69,"end":77},"obj":"Disease"},{"id":"T43","span":{"begin":490,"end":500},"obj":"Disease"}],"attributes":[{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"SARS-CoV-2 viral life cycle and potential targets for nanomaterials. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptors on the host cell surface. Transmembrane serine protease 2 (TMPRSS2) facilitates cellular entry through protease activity. Later, viral particles are internalized and enter into endosomes. Due to the low pH of endosomes, viral particles are uncoated and the viral genome is released for protein synthesis. Following viral RNA and protein synthesis, new infectious particles are assembled and released."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T79","span":{"begin":150,"end":154},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T80","span":{"begin":250,"end":258},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"SARS-CoV-2 viral life cycle and potential targets for nanomaterials. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptors on the host cell surface. Transmembrane serine protease 2 (TMPRSS2) facilitates cellular entry through protease activity. Later, viral particles are internalized and enter into endosomes. Due to the low pH of endosomes, viral particles are uncoated and the viral genome is released for protein synthesis. Following viral RNA and protein synthesis, new infectious particles are assembled and released."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T31","span":{"begin":89,"end":100},"obj":"Chemical"},{"id":"T32","span":{"begin":178,"end":184},"obj":"Chemical"},{"id":"T33","span":{"begin":424,"end":431},"obj":"Chemical"},{"id":"T34","span":{"begin":467,"end":474},"obj":"Chemical"}],"attributes":[{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_17822"},{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"SARS-CoV-2 viral life cycle and potential targets for nanomaterials. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptors on the host cell surface. Transmembrane serine protease 2 (TMPRSS2) facilitates cellular entry through protease activity. Later, viral particles are internalized and enter into endosomes. Due to the low pH of endosomes, viral particles are uncoated and the viral genome is released for protein synthesis. Following viral RNA and protein synthesis, new infectious particles are assembled and released."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T12","span":{"begin":11,"end":27},"obj":"http://purl.obolibrary.org/obo/GO_0019058"},{"id":"T13","span":{"begin":241,"end":258},"obj":"http://purl.obolibrary.org/obo/GO_0008233"},{"id":"T14","span":{"begin":424,"end":441},"obj":"http://purl.obolibrary.org/obo/GO_0006412"},{"id":"T15","span":{"begin":432,"end":441},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T16","span":{"begin":467,"end":484},"obj":"http://purl.obolibrary.org/obo/GO_0006412"},{"id":"T17","span":{"begin":475,"end":484},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"SARS-CoV-2 viral life cycle and potential targets for nanomaterials. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptors on the host cell surface. Transmembrane serine protease 2 (TMPRSS2) facilitates cellular entry through protease activity. Later, viral particles are internalized and enter into endosomes. Due to the low pH of endosomes, viral particles are uncoated and the viral genome is released for protein synthesis. Following viral RNA and protein synthesis, new infectious particles are assembled and released."}

{"project":"LitCovid-sentences","denotations":[{"id":"T35","span":{"begin":69,"end":163},"obj":"Sentence"},{"id":"T36","span":{"begin":164,"end":259},"obj":"Sentence"},{"id":"T37","span":{"begin":260,"end":325},"obj":"Sentence"},{"id":"T38","span":{"begin":326,"end":442},"obj":"Sentence"},{"id":"T39","span":{"begin":443,"end":538},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SARS-CoV-2 viral life cycle and potential targets for nanomaterials. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptors on the host cell surface. Transmembrane serine protease 2 (TMPRSS2) facilitates cellular entry through protease activity. Later, viral particles are internalized and enter into endosomes. Due to the low pH of endosomes, viral particles are uncoated and the viral genome is released for protein synthesis. Following viral RNA and protein synthesis, new infectious particles are assembled and released."}

{"project":"LitCovid-PubTator","denotations":[{"id":"156","span":{"begin":89,"end":120},"obj":"Gene"},{"id":"157","span":{"begin":122,"end":126},"obj":"Gene"},{"id":"158","span":{"begin":197,"end":204},"obj":"Gene"},{"id":"159","span":{"begin":0,"end":10},"obj":"Species"},{"id":"160","span":{"begin":69,"end":79},"obj":"Species"},{"id":"161","span":{"begin":178,"end":184},"obj":"Chemical"}],"attributes":[{"id":"A156","pred":"tao:has_database_id","subj":"156","obj":"Gene:59272"},{"id":"A157","pred":"tao:has_database_id","subj":"157","obj":"Gene:59272"},{"id":"A158","pred":"tao:has_database_id","subj":"158","obj":"Gene:7113"},{"id":"A159","pred":"tao:has_database_id","subj":"159","obj":"Tax:2697049"},{"id":"A160","pred":"tao:has_database_id","subj":"160","obj":"Tax:2697049"},{"id":"A161","pred":"tao:has_database_id","subj":"161","obj":"MESH:D012694"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"SARS-CoV-2 viral life cycle and potential targets for nanomaterials. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptors on the host cell surface. Transmembrane serine protease 2 (TMPRSS2) facilitates cellular entry through protease activity. Later, viral particles are internalized and enter into endosomes. Due to the low pH of endosomes, viral particles are uncoated and the viral genome is released for protein synthesis. Following viral RNA and protein synthesis, new infectious particles are assembled and released."}