PMC:7299399 / 63173-63923
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T307","span":{"begin":521,"end":528},"obj":"Body_part"},{"id":"T308","span":{"begin":576,"end":591},"obj":"Body_part"},{"id":"T309","span":{"begin":631,"end":638},"obj":"Body_part"}],"attributes":[{"id":"A307","pred":"fma_id","subj":"T307","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A308","pred":"fma_id","subj":"T308","obj":"http://purl.org/sig/ont/fma/fma63023"},{"id":"A309","pred":"fma_id","subj":"T309","obj":"http://purl.org/sig/ont/fma/fma82839"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T185","span":{"begin":215,"end":229},"obj":"Disease"},{"id":"T186","span":{"begin":251,"end":261},"obj":"Disease"}],"attributes":[{"id":"A185","pred":"mondo_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/MONDO_0004609"},{"id":"A186","pred":"mondo_id","subj":"T186","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T542","span":{"begin":230,"end":235},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T67480","span":{"begin":26,"end":34},"obj":"Chemical"},{"id":"T78787","span":{"begin":120,"end":134},"obj":"Chemical"},{"id":"T49088","span":{"begin":120,"end":128},"obj":"Chemical"},{"id":"T57903","span":{"begin":129,"end":134},"obj":"Chemical"},{"id":"T220","span":{"begin":136,"end":138},"obj":"Chemical"},{"id":"T40772","span":{"begin":160,"end":162},"obj":"Chemical"},{"id":"T50051","span":{"begin":365,"end":379},"obj":"Chemical"},{"id":"T223","span":{"begin":365,"end":373},"obj":"Chemical"},{"id":"T84352","span":{"begin":374,"end":379},"obj":"Chemical"},{"id":"T90555","span":{"begin":506,"end":514},"obj":"Chemical"},{"id":"T227","span":{"begin":521,"end":528},"obj":"Chemical"},{"id":"T605","span":{"begin":549,"end":556},"obj":"Chemical"},{"id":"T38358","span":{"begin":562,"end":570},"obj":"Chemical"},{"id":"T62069","span":{"begin":576,"end":591},"obj":"Chemical"},{"id":"T57750","span":{"begin":576,"end":583},"obj":"Chemical"},{"id":"T16513","span":{"begin":584,"end":591},"obj":"Chemical"},{"id":"T97171","span":{"begin":631,"end":638},"obj":"Chemical"},{"id":"T50538","span":{"begin":665,"end":681},"obj":"Chemical"},{"id":"T76185","span":{"begin":728,"end":741},"obj":"Chemical"}],"attributes":[{"id":"A29424","pred":"chebi_id","subj":"T67480","obj":"http://purl.obolibrary.org/obo/CHEBI_36973"},{"id":"A29497","pred":"chebi_id","subj":"T78787","obj":"http://purl.obolibrary.org/obo/CHEBI_132889"},{"id":"A30927","pred":"chebi_id","subj":"T49088","obj":"http://purl.obolibrary.org/obo/CHEBI_36973"},{"id":"A7127","pred":"chebi_id","subj":"T57903","obj":"http://purl.obolibrary.org/obo/CHEBI_25741"},{"id":"A64153","pred":"chebi_id","subj":"T57903","obj":"http://purl.obolibrary.org/obo/CHEBI_29356"},{"id":"A20203","pred":"chebi_id","subj":"T220","obj":"http://purl.obolibrary.org/obo/CHEBI_132889"},{"id":"A25745","pred":"chebi_id","subj":"T40772","obj":"http://purl.obolibrary.org/obo/CHEBI_132889"},{"id":"A91255","pred":"chebi_id","subj":"T50051","obj":"http://purl.obolibrary.org/obo/CHEBI_132889"},{"id":"A32029","pred":"chebi_id","subj":"T223","obj":"http://purl.obolibrary.org/obo/CHEBI_36973"},{"id":"A78367","pred":"chebi_id","subj":"T84352","obj":"http://purl.obolibrary.org/obo/CHEBI_25741"},{"id":"A20608","pred":"chebi_id","subj":"T84352","obj":"http://purl.obolibrary.org/obo/CHEBI_29356"},{"id":"A19686","pred":"chebi_id","subj":"T90555","obj":"http://purl.obolibrary.org/obo/CHEBI_36973"},{"id":"A33123","pred":"chebi_id","subj":"T227","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A55048","pred":"chebi_id","subj":"T605","obj":"http://purl.obolibrary.org/obo/CHEBI_16189"},{"id":"A51361","pred":"chebi_id","subj":"T38358","obj":"http://purl.obolibrary.org/obo/CHEBI_33839"},{"id":"A44220","pred":"chebi_id","subj":"T62069","obj":"http://purl.obolibrary.org/obo/CHEBI_28815"},{"id":"A31758","pred":"chebi_id","subj":"T57750","obj":"http://purl.obolibrary.org/obo/CHEBI_24500"},{"id":"A66660","pred":"chebi_id","subj":"T16513","obj":"http://purl.obolibrary.org/obo/CHEBI_16189"},{"id":"A54041","pred":"chebi_id","subj":"T97171","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A83020","pred":"chebi_id","subj":"T50538","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A46027","pred":"chebi_id","subj":"T76185","obj":"http://purl.obolibrary.org/obo/CHEBI_50249"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}
LitCovid-PD-GlycoEpitope
{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T6","span":{"begin":576,"end":591},"obj":"GlycoEpitope"}],"attributes":[{"id":"A6","pred":"glyco_epitope_db_id","subj":"T6","obj":"http://www.glycoepitope.jp/epitopes/EP0086"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T246","span":{"begin":0,"end":750},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"977","span":{"begin":215,"end":242},"obj":"Species"},{"id":"981","span":{"begin":26,"end":34},"obj":"Chemical"},{"id":"982","span":{"begin":120,"end":134},"obj":"Chemical"},{"id":"983","span":{"begin":136,"end":138},"obj":"Chemical"},{"id":"984","span":{"begin":160,"end":162},"obj":"Chemical"},{"id":"985","span":{"begin":365,"end":379},"obj":"Chemical"},{"id":"986","span":{"begin":381,"end":384},"obj":"Chemical"},{"id":"987","span":{"begin":441,"end":453},"obj":"Chemical"},{"id":"988","span":{"begin":455,"end":458},"obj":"Chemical"},{"id":"989","span":{"begin":506,"end":514},"obj":"Chemical"},{"id":"990","span":{"begin":521,"end":528},"obj":"Chemical"},{"id":"991","span":{"begin":549,"end":556},"obj":"Chemical"},{"id":"992","span":{"begin":576,"end":591},"obj":"Chemical"},{"id":"993","span":{"begin":631,"end":638},"obj":"Chemical"},{"id":"995","span":{"begin":243,"end":261},"obj":"Disease"}],"attributes":[{"id":"A977","pred":"tao:has_database_id","subj":"977","obj":"Tax:10298"},{"id":"A981","pred":"tao:has_database_id","subj":"981","obj":"MESH:D006108"},{"id":"A982","pred":"tao:has_database_id","subj":"982","obj":"MESH:C000628730"},{"id":"A983","pred":"tao:has_database_id","subj":"983","obj":"MESH:C000628730"},{"id":"A984","pred":"tao:has_database_id","subj":"984","obj":"MESH:C000628730"},{"id":"A985","pred":"tao:has_database_id","subj":"985","obj":"MESH:C000628730"},{"id":"A987","pred":"tao:has_database_id","subj":"987","obj":"MESH:C043941"},{"id":"A989","pred":"tao:has_database_id","subj":"989","obj":"MESH:D006108"},{"id":"A990","pred":"tao:has_database_id","subj":"990","obj":"MESH:D006493"},{"id":"A991","pred":"tao:has_database_id","subj":"991","obj":"MESH:D013431"},{"id":"A992","pred":"tao:has_database_id","subj":"992","obj":"MESH:D006497"},{"id":"A993","pred":"tao:has_database_id","subj":"993","obj":"MESH:D006493"},{"id":"A995","pred":"tao:has_database_id","subj":"995","obj":"MESH:C536395"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}
2_test
{"project":"2_test","denotations":[{"id":"32519842-24364493-158602","span":{"begin":343,"end":346},"obj":"24364493"},{"id":"32519842-28266670-158603","span":{"begin":541,"end":544},"obj":"28266670"},{"id":"32519842-11405655-158604","span":{"begin":682,"end":685},"obj":"11405655"},{"id":"32519842-17452490-158605","span":{"begin":686,"end":689},"obj":"17452490"}],"text":"In addition to metal NPs, graphene derivatives have also shown promising viral inactivation properties.174 For example, graphene oxide (GO) sheets and sulfated GO derivatives have been found to be effective against herpes simplex virus type-1 (HSV-1) infections, with viral binding and shielding as the two putative main inhibitory mechanisms.175 Thermally reduced graphene oxide (rGO) sheets functionalized with biocompatible hyperbranched polyglycerol (hPG) and then sulfated have also been generated as graphene-based heparin biomimetics.176−178 Sulfate-rich polymers like heparan sulfate and its equivalent soluble counterpart heparin are widely known as broad antiviral agents,179,180 but their use is limited due to their anticoagulant effects."}