PMC:7299399 / 5750-6089 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T15","span":{"begin":0,"end":5},"obj":"Body_part"},{"id":"T16","span":{"begin":105,"end":112},"obj":"Body_part"},{"id":"T17","span":{"begin":277,"end":284},"obj":"Body_part"}],"attributes":[{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"cells.19,21−23\nThe C-terminal domain (i.e., receptor-binding domain of the envelope-embedded spike (S) 1 protein) of SARS-CoV-2 binds ACE2. The molecular details of this interaction have been provided by solving the crystal structure of the complex.24 Because binding of the S protein to ACE2 is critical for the first steps of infection, "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T36","span":{"begin":117,"end":125},"obj":"Disease"},{"id":"T37","span":{"begin":328,"end":337},"obj":"Disease"}],"attributes":[{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"cells.19,21−23\nThe C-terminal domain (i.e., receptor-binding domain of the envelope-embedded spike (S) 1 protein) of SARS-CoV-2 binds ACE2. The molecular details of this interaction have been provided by solving the crystal structure of the complex.24 Because binding of the S protein to ACE2 is critical for the first steps of infection, "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T56","span":{"begin":0,"end":5},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T57","span":{"begin":99,"end":104},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"}],"text":"cells.19,21−23\nThe C-terminal domain (i.e., receptor-binding domain of the envelope-embedded spike (S) 1 protein) of SARS-CoV-2 binds ACE2. The molecular details of this interaction have been provided by solving the crystal structure of the complex.24 Because binding of the S protein to ACE2 is critical for the first steps of infection, "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T19","span":{"begin":105,"end":112},"obj":"Chemical"},{"id":"T20","span":{"begin":277,"end":284},"obj":"Chemical"}],"attributes":[{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"cells.19,21−23\nThe C-terminal domain (i.e., receptor-binding domain of the envelope-embedded spike (S) 1 protein) of SARS-CoV-2 binds ACE2. The molecular details of this interaction have been provided by solving the crystal structure of the complex.24 Because binding of the S protein to ACE2 is critical for the first steps of infection, "}

{"project":"LitCovid-sentences","denotations":[{"id":"T28","span":{"begin":15,"end":139},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"cells.19,21−23\nThe C-terminal domain (i.e., receptor-binding domain of the envelope-embedded spike (S) 1 protein) of SARS-CoV-2 binds ACE2. The molecular details of this interaction have been provided by solving the crystal structure of the complex.24 Because binding of the S protein to ACE2 is critical for the first steps of infection, "}

{"project":"LitCovid-PubTator","denotations":[{"id":"128","span":{"begin":134,"end":138},"obj":"Gene"},{"id":"129","span":{"begin":288,"end":292},"obj":"Gene"},{"id":"136","span":{"begin":117,"end":127},"obj":"Species"},{"id":"137","span":{"begin":328,"end":337},"obj":"Disease"}],"attributes":[{"id":"A128","pred":"tao:has_database_id","subj":"128","obj":"Gene:59272"},{"id":"A129","pred":"tao:has_database_id","subj":"129","obj":"Gene:59272"},{"id":"A136","pred":"tao:has_database_id","subj":"136","obj":"Tax:2697049"},{"id":"A137","pred":"tao:has_database_id","subj":"137","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"cells.19,21−23\nThe C-terminal domain (i.e., receptor-binding domain of the envelope-embedded spike (S) 1 protein) of SARS-CoV-2 binds ACE2. The molecular details of this interaction have been provided by solving the crystal structure of the complex.24 Because binding of the S protein to ACE2 is critical for the first steps of infection, "}

{"project":"2_test","denotations":[{"id":"32519842-32015507-158456","span":{"begin":6,"end":8},"obj":"32015507"},{"id":"32519842-32333836-158457","span":{"begin":9,"end":11},"obj":"32333836"},{"id":"32519842-32142651-158458","span":{"begin":12,"end":14},"obj":"32142651"},{"id":"32519842-32275855-158459","span":{"begin":249,"end":251},"obj":"32275855"}],"text":"cells.19,21−23\nThe C-terminal domain (i.e., receptor-binding domain of the envelope-embedded spike (S) 1 protein) of SARS-CoV-2 binds ACE2. The molecular details of this interaction have been provided by solving the crystal structure of the complex.24 Because binding of the S protein to ACE2 is critical for the first steps of infection, "}