PMC:7299399 / 53559-55054 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7299399","sourcedb":"PMC","sourceid":"7299399","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7299399","text":"SARS-CoV is highly stable at room temperature and at 4 °C, but it is inactivated by ultraviolet light at 254 nm, highly alkaline or acidic conditions of pH \u003e12 or pH \u003c3, respectively, or by brief (e.g., 5 min) heat treatment at 65 °C. SARS-CoV-2 is expected to be similarly sensitive.150 Several human coronaviruses can be inactivated by classical disinfectants, including bleach, ethanol, povidone-iodine, chloroxylenol, chlorheximide, and benzalkonium chloride,151 so we expect similar inactivation with SARS-CoV-2. The virus stability on surfaces depends on the composition of the infected material, with inactivation in \u003c3 h on printing and tissue paper, in \u003c2 days on treated wood and cloth, in \u003c4 days on glass and banknotes, and in \u003c7 days on stainless steel and plastic.152 Conversely, active viruses can remain on the outer layer of a surgical mask even after 7 days.152 The surface and aerosol stability of SARS-CoV-2 is comparable to that of SARS-CoV-1,153 with both viruses remaining viable in contaminated aerosols for more than 3 h. Infectious SARS-CoV-1 and SARS-CoV-2 remain viable up to 72 h after inoculation on plastic and stainless steel, whereas both are inactivated on copper in less than 4 or 8 h, respectively, and on cardboards in less than 24 and 8 h, respectively.153 Therefore, the stability of both viruses is similar, and we can hypothesize that surface treatments with NPs that proved to be effective for SARS-CoV-1 could possibly also be effective for 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