PMC:7295558 / 4025-5059 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T37","span":{"begin":14,"end":17},"obj":"NCBITaxon:9606"},{"id":"T38","span":{"begin":93,"end":99},"obj":"UBERON:0002048"},{"id":"T39","span":{"begin":153,"end":161},"obj":"UBERON:0002367"},{"id":"T40","span":{"begin":274,"end":281},"obj":"UBERON:0000948"},{"id":"T41","span":{"begin":338,"end":348},"obj":"UBERON:0002349"},{"id":"T42","span":{"begin":366,"end":373},"obj":"CHEBI:24996;CHEBI:24996"},{"id":"T43","span":{"begin":400,"end":412},"obj":"SP_10"},{"id":"T44","span":{"begin":413,"end":424},"obj":"SP_10;UBERON:0001004"},{"id":"T45","span":{"begin":425,"end":442},"obj":"SP_10"},{"id":"T46","span":{"begin":525,"end":530},"obj":"UBERON:0000004"},{"id":"T47","span":{"begin":650,"end":652},"obj":"UBERON:0000948"},{"id":"T48","span":{"begin":854,"end":861},"obj":"UBERON:0003221"},{"id":"T49","span":{"begin":937,"end":943},"obj":"UBERON:0002113"},{"id":"T50","span":{"begin":970,"end":980},"obj":"UBERON:0000062"},{"id":"T53383","span":{"begin":14,"end":17},"obj":"NCBITaxon:9606"},{"id":"T983","span":{"begin":93,"end":99},"obj":"UBERON:0002048"},{"id":"T67585","span":{"begin":153,"end":161},"obj":"UBERON:0002367"},{"id":"T35773","span":{"begin":274,"end":281},"obj":"UBERON:0000948"},{"id":"T52018","span":{"begin":338,"end":348},"obj":"UBERON:0002349"},{"id":"T43986","span":{"begin":366,"end":373},"obj":"CHEBI:24996;CHEBI:24996"},{"id":"T48562","span":{"begin":400,"end":412},"obj":"SP_10"},{"id":"T96757","span":{"begin":413,"end":424},"obj":"SP_10;UBERON:0001004"},{"id":"T10381","span":{"begin":425,"end":442},"obj":"SP_10"},{"id":"T22457","span":{"begin":525,"end":530},"obj":"UBERON:0000004"},{"id":"T1665","span":{"begin":650,"end":652},"obj":"UBERON:0000948"},{"id":"T42265","span":{"begin":854,"end":861},"obj":"UBERON:0003221"},{"id":"T57265","span":{"begin":937,"end":943},"obj":"UBERON:0002113"},{"id":"T7155","span":{"begin":970,"end":980},"obj":"UBERON:0000062"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":153,"end":161},"obj":"Body_part"},{"id":"T5","span":{"begin":937,"end":943},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma9600"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma7203"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T5","span":{"begin":937,"end":943},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T23","span":{"begin":153,"end":168},"obj":"Disease"},{"id":"T24","span":{"begin":162,"end":168},"obj":"Disease"},{"id":"T25","span":{"begin":253,"end":263},"obj":"Disease"},{"id":"T26","span":{"begin":317,"end":319},"obj":"Disease"},{"id":"T27","span":{"begin":355,"end":357},"obj":"Disease"},{"id":"T28","span":{"begin":407,"end":442},"obj":"Disease"},{"id":"T29","span":{"begin":413,"end":442},"obj":"Disease"},{"id":"T30","span":{"begin":444,"end":448},"obj":"Disease"},{"id":"T31","span":{"begin":825,"end":837},"obj":"Disease"},{"id":"T32","span":{"begin":915,"end":917},"obj":"Disease"},{"id":"T33","span":{"begin":931,"end":950},"obj":"Disease"},{"id":"T34","span":{"begin":944,"end":950},"obj":"Disease"},{"id":"T35","span":{"begin":952,"end":955},"obj":"Disease"},{"id":"T36","span":{"begin":962,"end":968},"obj":"Disease"},{"id":"T37","span":{"begin":970,"end":988},"obj":"Disease"},{"id":"T38","span":{"begin":993,"end":1001},"obj":"Disease"}],"attributes":[{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0008315"},{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"},{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0003785"},{"id":"A26","pred":"mondo_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"},{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"},{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0002076"},{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0017319"},{"id":"A33","pred":"mondo_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/MONDO_0002492"},{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A35","pred":"mondo_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/MONDO_0002492"},{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0002476"},{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0043726"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0006022"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T30","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T31","span":{"begin":60,"end":64},"obj":"http://purl.obolibrary.org/obo/CLO_0001550"},{"id":"T32","span":{"begin":129,"end":130},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T33","span":{"begin":358,"end":360},"obj":"http://purl.obolibrary.org/obo/PR_000010213"},{"id":"T34","span":{"begin":398,"end":399},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T35","span":{"begin":455,"end":456},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T36","span":{"begin":513,"end":514},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T37","span":{"begin":572,"end":573},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T38","span":{"begin":678,"end":680},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T39","span":{"begin":686,"end":687},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T40","span":{"begin":817,"end":818},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T41","span":{"begin":852,"end":853},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T42","span":{"begin":937,"end":943},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T43","span":{"begin":937,"end":943},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T44","span":{"begin":937,"end":943},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T7","span":{"begin":300,"end":308},"obj":"Chemical"},{"id":"T9","span":{"begin":322,"end":330},"obj":"Chemical"},{"id":"T11","span":{"begin":366,"end":373},"obj":"Chemical"},{"id":"T12","span":{"begin":650,"end":652},"obj":"Chemical"}],"attributes":[{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_16919"},{"id":"A8","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_57947"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_16919"},{"id":"A10","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_57947"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_24996"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_73579"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T3","span":{"begin":355,"end":360},"obj":"http://purl.obolibrary.org/obo/GO_0004111"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-sentences","denotations":[{"id":"T39","span":{"begin":0,"end":121},"obj":"Sentence"},{"id":"T40","span":{"begin":122,"end":194},"obj":"Sentence"},{"id":"T41","span":{"begin":195,"end":245},"obj":"Sentence"},{"id":"T42","span":{"begin":246,"end":571},"obj":"Sentence"},{"id":"T43","span":{"begin":572,"end":626},"obj":"Sentence"},{"id":"T44","span":{"begin":627,"end":700},"obj":"Sentence"},{"id":"T45","span":{"begin":701,"end":756},"obj":"Sentence"},{"id":"T46","span":{"begin":757,"end":886},"obj":"Sentence"},{"id":"T47","span":{"begin":887,"end":1002},"obj":"Sentence"},{"id":"T48","span":{"begin":1003,"end":1034},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T8","span":{"begin":80,"end":99},"obj":"Phenotype"},{"id":"T9","span":{"begin":101,"end":106},"obj":"Phenotype"},{"id":"T10","span":{"begin":111,"end":120},"obj":"Phenotype"},{"id":"T11","span":{"begin":153,"end":168},"obj":"Phenotype"},{"id":"T12","span":{"begin":253,"end":263},"obj":"Phenotype"},{"id":"T13","span":{"begin":413,"end":433},"obj":"Phenotype"},{"id":"T14","span":{"begin":825,"end":837},"obj":"Phenotype"},{"id":"T15","span":{"begin":931,"end":950},"obj":"Phenotype"},{"id":"T16","span":{"begin":952,"end":955},"obj":"Phenotype"},{"id":"T17","span":{"begin":962,"end":968},"obj":"Phenotype"},{"id":"T18","span":{"begin":993,"end":1001},"obj":"Phenotype"}],"attributes":[{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0031246"},{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0012125"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0001882"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0002107"},{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0001919"},{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0001919"},{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0100519"},{"id":"A18","pred":"hp_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/HP_0001941"}],"text":"A 76-year-old man presented to the emergency room (ER) with a 10-day history of shortness of breath, fever and dry cough. He had a previous diagnosis of prostate cancer, currently in remittance. His baseline characteristics are shown in Table 1. He had leukopenia, elevated cardiac markers including creatine kinase (CK), creatine kinase myocardial band (CK-MB) and lactate dehydrogenase (LDH) and a severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio of 59, which was initially treated with a high-flow nasal cannula (HFNC) and supportive treatment. A TTE was performed during day 8 of his hospital stay. This revealed abnormal LV function with an LVEF of 35% and a GLS of -14%. Echocardiographic characteristics are shown in Table 2. He was intubated the next day and developed barotrauma with a right pneumothorax that required a pleural catheter for evacuation. Afterward, on his 10th day, he developed an acute kidney injury (AKI) with anuria, multiorgan failure and acidosis. He passed away on his 11th day."}

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