PMC:7295558 / 1784-3008 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7295558","sourcedb":"PMC","sourceid":"7295558","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7295558","text":"Introduction\nIn December 2019, a wave of cases of atypical pneumonia emerged from Wuhan City, Hubei Province in China [1, 2]. This disease (coronavirus disease 2019 (COVID-19)) is caused by the beta coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has rapidly spread around the world, being declared a pandemic since March 11. Early reports suggest that COVID-19 is generally mild; nevertheless, up to 19% of cases will require in-hospital management, and 6% will need to be admitted to the intensive care unit (ICU) [3]. Although COVID-19 manifests in most patients with respiratory symptoms, other presentations can occur, and it has been suggested that there could be direct damage to the cardiovascular system [4-6]. In addition, increasing concern exists regarding the severity of the disease in patients with prior cardiovascular disease (CVD), since this group has a worse prognosis [7, 8]. Transthoracic echocardiography (TTE) allows us to detect subtle myocardial damage with tools that are associated with prognosis, e.g. left ventricular ejection fraction (LVEF) or global longitudinal strain (GLS) [9]. Herein, we present the echocardiographic findings in four patients with 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