PMC:7295011 / 4881-5259 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T82","span":{"begin":37,"end":44},"obj":"SO:0000704"},{"id":"T83","span":{"begin":61,"end":67},"obj":"PR:000004690"},{"id":"T84","span":{"begin":68,"end":72},"obj":"SO:0000704"},{"id":"T85","span":{"begin":92,"end":98},"obj":"SO:0001026"},{"id":"T86","span":{"begin":227,"end":234},"obj":"SO:0000704"},{"id":"T87","span":{"begin":271,"end":279},"obj":"GO:0065007"},{"id":"T88","span":{"begin":317,"end":328},"obj":"CL:0000740"},{"id":"T31772","span":{"begin":37,"end":44},"obj":"SO:0000704"},{"id":"T50101","span":{"begin":61,"end":67},"obj":"PR:000004690"},{"id":"T63374","span":{"begin":68,"end":72},"obj":"SO:0000704"},{"id":"T29873","span":{"begin":92,"end":98},"obj":"SO:0001026"},{"id":"T83318","span":{"begin":227,"end":234},"obj":"SO:0000704"},{"id":"T2944","span":{"begin":271,"end":279},"obj":"GO:0065007"},{"id":"T77581","span":{"begin":317,"end":328},"obj":"CL:0000740"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T8","span":{"begin":68,"end":72},"obj":"Body_part"},{"id":"T9","span":{"begin":92,"end":98},"obj":"Body_part"},{"id":"T10","span":{"begin":140,"end":150},"obj":"Body_part"},{"id":"T11","span":{"begin":324,"end":328},"obj":"Body_part"}],"attributes":[{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma62293"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"110","span":{"begin":61,"end":67},"obj":"Gene"},{"id":"120","span":{"begin":301,"end":312},"obj":"Disease"}],"attributes":[{"id":"A110","pred":"tao:has_database_id","subj":"110","obj":"Gene:53335"},{"id":"A120","pred":"tao:has_database_id","subj":"120","obj":"MESH:D013789"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T37","span":{"begin":296,"end":312},"obj":"Disease"},{"id":"T38","span":{"begin":301,"end":312},"obj":"Disease"},{"id":"T39","span":{"begin":317,"end":337},"obj":"Disease"}],"attributes":[{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0013517"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0000984"},{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0011382"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T33","span":{"begin":68,"end":72},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T34","span":{"begin":324,"end":328},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T12","span":{"begin":140,"end":150},"obj":"Chemical"},{"id":"T13","span":{"begin":296,"end":300},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_35143"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_10545"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T28","span":{"begin":0,"end":378},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"2_test","denotations":[{"id":"32582302-17767159-33453884","span":{"begin":210,"end":214},"obj":"17767159"},{"id":"32582302-18667698-33453885","span":{"begin":354,"end":358},"obj":"18667698"},{"id":"32582302-18245381-33453886","span":{"begin":372,"end":376},"obj":"18245381"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}

{"project":"MyTest","denotations":[{"id":"32582302-17767159-33453884","span":{"begin":210,"end":214},"obj":"17767159"},{"id":"32582302-18667698-33453885","span":{"begin":354,"end":358},"obj":"18667698"},{"id":"32582302-18245381-33453886","span":{"begin":372,"end":376},"obj":"18245381"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"In one example of how this can work, genetic variants in the BCL11A gene were associated by genome-wide association studies (GWAS) to fetal hemoglobin (HbF) production in the general population (Menzel et al., 2007), and these genetic variants were subsequently found to modulate the severity of beta-thalassemia and sickle cell diseases (Lettre et al., 2008; Uda et al., 2008)."}