PMC:7291971 / 7927-8238 JSONTXT

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{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T43","span":{"begin":109,"end":116},"obj":"Body_part"},{"id":"T44","span":{"begin":197,"end":200},"obj":"Body_part"}],"attributes":[{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma82774"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"oupling of a 2′-O-ethyl adenosine to a 5′-amino adenosine. We explored a variety of N-substituted linkers in adenine dinucleosides and their inhibition activity was evaluated against several viral RNA 2′O-MTases as well N7-MTases for specificity purpose. Unexpectedly, none of the N-linked dinucleosides inhibit"}

{"project":"LitCovid-PubTator","denotations":[{"id":"98","span":{"begin":24,"end":33},"obj":"Chemical"},{"id":"99","span":{"begin":48,"end":57},"obj":"Chemical"},{"id":"100","span":{"begin":84,"end":85},"obj":"Chemical"},{"id":"101","span":{"begin":109,"end":130},"obj":"Chemical"}],"attributes":[{"id":"A98","pred":"tao:has_database_id","subj":"98","obj":"MESH:D000241"},{"id":"A99","pred":"tao:has_database_id","subj":"99","obj":"MESH:D000241"},{"id":"A100","pred":"tao:has_database_id","subj":"100","obj":"MESH:D009584"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"oupling of a 2′-O-ethyl adenosine to a 5′-amino adenosine. We explored a variety of N-substituted linkers in adenine dinucleosides and their inhibition activity was evaluated against several viral RNA 2′O-MTases as well N7-MTases for specificity purpose. Unexpectedly, none of the N-linked dinucleosides inhibit"}

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{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T93","span":{"begin":18,"end":23},"obj":"Chemical"},{"id":"T95","span":{"begin":24,"end":33},"obj":"Chemical"},{"id":"T96","span":{"begin":42,"end":47},"obj":"Chemical"},{"id":"T97","span":{"begin":48,"end":57},"obj":"Chemical"},{"id":"T98","span":{"begin":109,"end":116},"obj":"Chemical"}],"attributes":[{"id":"A93","pred":"chebi_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/CHEBI_37807"},{"id":"A94","pred":"chebi_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/CHEBI_62801"},{"id":"A95","pred":"chebi_id","subj":"T95","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"},{"id":"A96","pred":"chebi_id","subj":"T96","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A97","pred":"chebi_id","subj":"T97","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"},{"id":"A98","pred":"chebi_id","subj":"T98","obj":"http://purl.obolibrary.org/obo/CHEBI_16708"}],"text":"oupling of a 2′-O-ethyl adenosine to a 5′-amino adenosine. We explored a variety of N-substituted linkers in adenine dinucleosides and their inhibition activity was evaluated against several viral RNA 2′O-MTases as well N7-MTases for specificity purpose. Unexpectedly, none of the N-linked dinucleosides inhibit"}

{"project":"LitCovid-sentences","denotations":[{"id":"T54","span":{"begin":59,"end":254},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"oupling of a 2′-O-ethyl adenosine to a 5′-amino adenosine. We explored a variety of N-substituted linkers in adenine dinucleosides and their inhibition activity was evaluated against several viral RNA 2′O-MTases as well N7-MTases for specificity purpose. Unexpectedly, none of the N-linked dinucleosides inhibit"}