> top > docs > PMC:7291971 > spans > 52054-53441 > annotations

PMC:7291971 / 52054-53441 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T1057 56-88 CHEBI:53233;CHEBI:53233 denotes 2-dimethyl-tetrahydro-2H-furo[3,
T1058 89-90 CHEBI:53233;CHEBI:53233 denotes -
T1059 94-95 CHEBI:53233;CHEBI:53233 denotes 1
T1060 95-97 CHEBI:52029;CHEBI:52029 denotes ,3
T1061 97-98 CHEBI:53233;CHEBI:53233 denotes ]
T1062 98-104 CHEBI:52029;CHEBI:52029 denotes dioxol
T1063 104-110 CHEBI:53233;CHEBI:53233 denotes -4-yl]
T1064 110-116 CHEBI:29309;CHEBI:29309 denotes methyl
T1065 160-165 CHEBI:53233;CHEBI:53233 denotes tert-
T1066 165-183 CHEBI:28714;CHEBI:28714 denotes butyldimethylsilyl
T1067 183-184 CHEBI:53233;CHEBI:53233 denotes )
T1068 184-187 CHEBI:29354;CHEBI:29354 denotes oxy
T1069 187-192 CHEBI:53233;CHEBI:53233 denotes ]-5-{
T1070 193-199 CHEBI:53233;CHEBI:53233 denotes (tert-
T1071 199-217 CHEBI:8502;CHEBI:8502 denotes butyldimethylsilyl
T1072 217-218 CHEBI:53233;CHEBI:53233 denotes )
T1073 218-221 CHEBI:29354;CHEBI:29354 denotes oxy
T1074 222-228 CHEBI:29309;CHEBI:29309 denotes methyl
T1075 229-235 CHEBI:26911;CHEBI:26911 denotes oxolan
T1076 235-241 CHEBI:53233;CHEBI:53233 denotes -3-yl]
T1077 241-244 CHEBI:29354;CHEBI:29354 denotes oxy
T1078 245-250 CHEBI:37807;CHEBI:37807 denotes ethyl
T1079 257-266 CHEBI:17968;CHEBI:17968 denotes butanoate
T1080 413-417 CHEBI:32145;CHEBI:32145 denotes MeOH
T1081 446-451 CHEBI:30808;CHEBI:30808 denotes CDCl3
T1082 1044-1047 CHEBI:36927;CHEBI:36927 denotes 13C
T75110 56-88 CHEBI:53233;CHEBI:53233 denotes 2-dimethyl-tetrahydro-2H-furo[3,
T17943 89-90 CHEBI:53233;CHEBI:53233 denotes -
T24037 94-95 CHEBI:53233;CHEBI:53233 denotes 1
T86603 95-97 CHEBI:52029;CHEBI:52029 denotes ,3
T59348 97-98 CHEBI:53233;CHEBI:53233 denotes ]
T37288 98-104 CHEBI:52029;CHEBI:52029 denotes dioxol
T39000 104-110 CHEBI:53233;CHEBI:53233 denotes -4-yl]
T31856 110-116 CHEBI:29309;CHEBI:29309 denotes methyl
T47118 160-165 CHEBI:53233;CHEBI:53233 denotes tert-
T15383 165-183 CHEBI:28714;CHEBI:28714 denotes butyldimethylsilyl
T47564 183-184 CHEBI:53233;CHEBI:53233 denotes )
T29123 184-187 CHEBI:29354;CHEBI:29354 denotes oxy
T88497 187-192 CHEBI:53233;CHEBI:53233 denotes ]-5-{
T48709 193-199 CHEBI:53233;CHEBI:53233 denotes (tert-
T67159 199-217 CHEBI:8502;CHEBI:8502 denotes butyldimethylsilyl
T41322 217-218 CHEBI:53233;CHEBI:53233 denotes )
T77050 218-221 CHEBI:29354;CHEBI:29354 denotes oxy
T15677 222-228 CHEBI:29309;CHEBI:29309 denotes methyl
T31769 229-235 CHEBI:26911;CHEBI:26911 denotes oxolan
T33192 235-241 CHEBI:53233;CHEBI:53233 denotes -3-yl]
T11035 241-244 CHEBI:29354;CHEBI:29354 denotes oxy
T21898 245-250 CHEBI:37807;CHEBI:37807 denotes ethyl
T71397 257-266 CHEBI:17968;CHEBI:17968 denotes butanoate
T12961 413-417 CHEBI:32145;CHEBI:32145 denotes MeOH
T70489 446-451 CHEBI:30808;CHEBI:30808 denotes CDCl3
T84309 1044-1047 CHEBI:36927;CHEBI:36927 denotes 13C

LitCovid-PubTator

Id Subject Object Predicate Lexical cue
909 332-354 Chemical denotes methyl-4-bromobutyrate
910 413-417 Chemical denotes MeOH
911 418-421 Chemical denotes DCM
912 1338-1352 Chemical denotes C42H70N11O9Si2
913 1311-1315 Disease denotes HRMS

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T333 389-390 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T334 1354-1357 http://purl.obolibrary.org/obo/CLO_0007706 denotes M+H

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T53 31-52 Chemical denotes 6-amino-9H-purin-9-yl http://purl.obolibrary.org/obo/CHEBI_30756
T18926 33-38 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T85668 58-66 Chemical denotes dimethyl http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266
T94799 110-116 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T45895 133-154 Chemical denotes 6-amino-9H-purin-9-yl http://purl.obolibrary.org/obo/CHEBI_30756
T47614 135-140 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T61 184-187 Chemical denotes oxy http://purl.obolibrary.org/obo/CHEBI_29354
T3622 218-221 Chemical denotes oxy http://purl.obolibrary.org/obo/CHEBI_29354
T97877 222-228 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T40837 241-244 Chemical denotes oxy http://purl.obolibrary.org/obo/CHEBI_29354
T48012 245-250 Chemical denotes ethyl http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801
T30820 251-256 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T18158 257-266 Chemical denotes butanoate http://purl.obolibrary.org/obo/CHEBI_17968
T72997 332-338 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T73357 404-406 Chemical denotes Rf http://purl.obolibrary.org/obo/CHEBI_33346
T73 413-417 Chemical denotes MeOH http://purl.obolibrary.org/obo/CHEBI_17790
T61099 418-421 Chemical denotes DCM http://purl.obolibrary.org/obo/CHEBI_15767
T38107 429-431 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T76 446-451 Chemical denotes CDCl3 http://purl.obolibrary.org/obo/CHEBI_85365
T45520 464-466 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T14016 478-480 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T17378 492-494 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T66161 506-508 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T52308 532-534 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T33388 585-587 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T83 624-626 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T95802 650-652 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T79068 708-710 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T46465 748-750 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T71575 788-790 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T41446 847-849 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T33129 906-908 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T78609 1062-1067 Chemical denotes CDCl3 http://purl.obolibrary.org/obo/CHEBI_85365

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T21 418-421 Phenotype denotes DCM http://purl.obolibrary.org/obo/HP_0001644

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T372 0-271 Sentence denotes 4.1.16 Methyl 4-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)amino)butanoate (25)
T373 272-403 Sentence denotes Following method D with 20 (600 mg, 0.73 mmol, 1.00 eq) and methyl-4-bromobutyrate, 25 (390 mg, 58%) was obtained as a white solid.
T374 404-428 Sentence denotes Rf 0.34 (MeOH/DCM 5:95).
T375 429-1043 Sentence denotes 1H NMR (600 MHz, CDCl3) δ 8.32 (s, 1H), 8.31 (s, 1H), 8.17 (s, 1H), 7.90 (s, 1H), 6.11 (d, J = 3.6 Hz, 1H), 6.02 (m, 5H), 5.45 (dd, J = 6.5 Hz, J = 2.2 Hz, 1H), 4.91 (dd, J = 6.6 Hz, J = 3.3 Hz, 1H), 4.51 (t, J = 5.3 Hz, 1H), 4.32–4.23 (m, 2H), 4.08 (dt, J = 6.1 Hz, J = 3.2 Hz, 1H), 3.99 (dd, J = 11.5 Hz, J = 3.6 Hz, 1H), 3.76 (dd, J = 11.5 Hz, J = 2.8 Hz, 1H), 3.71–3.60 (m, 5H), 2.77 (dd, J = 13.5 Hz, J = 6.9 Hz, 1H), 2.74–2.69 (m, 2H), 2.64 (dd, J = 13.5 Hz, J = 6.8 Hz, 1H), 2.51–2.44 (m, 2H), 2.32–2.18 (m, 2H), 1.69–1.61 (m, 2H), 1.58 (s, 3H), 1.37 (s, 3H), 0.92 (s, 9H), 0.90 (s, 9H), 0.13–0.04 (m, 12H).
T376 1044-1310 Sentence denotes 13C NMR (150 MHz, CDCl3) δ 174.0, 155.7, 155.6, 153.2, 153.1, 149.7, 149.4, 140.1, 139.5, 120.5, 120.3, 114.4, 91.1, 87.2, 85.7, 84.8, 83.9, 83.3, 82.5, 69.8, 69.3, 61.9, 56.7, 54.3, 53.7, 51.6, 31.5, 27.2, 26.1, 25.8, 25.5, 22.6, 18.6, 18.2, −4.4, −4.6, −5.2, −5.2.
T377 1311-1360 Sentence denotes HRMS (ESI+): m/z calcd for C42H70N11O9Si2 [M+H]+:
T378 1361-1377 Sentence denotes 928.4897, found:
T379 1378-1387 Sentence denotes 928.4900.