PMC:7291971 / 42948-43225 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T904","span":{"begin":102,"end":108},"obj":"CHEBI:34683;CHEBI:34683"},{"id":"T905","span":{"begin":197,"end":203},"obj":"CHEBI:30563;CHEBI:30563"},{"id":"T906","span":{"begin":230,"end":234},"obj":"CHEBI:32145;CHEBI:32145"},{"id":"T30010","span":{"begin":102,"end":108},"obj":"CHEBI:34683;CHEBI:34683"},{"id":"T67189","span":{"begin":197,"end":203},"obj":"CHEBI:30563;CHEBI:30563"},{"id":"T22030","span":{"begin":230,"end":234},"obj":"CHEBI:32145;CHEBI:32145"}],"text":"s extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. The residue was purified by flash column chromatography (silica gel, linear gradient 0–8% MeOH in DCM) to give 22 (321 mg, 93%) as a whit"}

{"project":"LitCovid-PubTator","denotations":[{"id":"768","span":{"begin":17,"end":20},"obj":"Chemical"},{"id":"769","span":{"begin":84,"end":89},"obj":"Chemical"},{"id":"770","span":{"begin":102,"end":108},"obj":"Chemical"},{"id":"771","span":{"begin":197,"end":207},"obj":"Chemical"},{"id":"772","span":{"begin":230,"end":234},"obj":"Chemical"},{"id":"773","span":{"begin":238,"end":241},"obj":"Chemical"}],"attributes":[{"id":"A769","pred":"tao:has_database_id","subj":"769","obj":"MESH:C017082"},{"id":"A771","pred":"tao:has_database_id","subj":"771","obj":"MESH:D058428"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"s extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. The residue was purified by flash column chromatography (silica gel, linear gradient 0–8% MeOH in DCM) to give 22 (321 mg, 93%) as a whit"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T302","span":{"begin":50,"end":57},"obj":"http://purl.obolibrary.org/obo/OBI_0100026"},{"id":"T303","span":{"begin":50,"end":57},"obj":"http://purl.obolibrary.org/obo/UBERON_0000468"},{"id":"T304","span":{"begin":251,"end":253},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T305","span":{"begin":259,"end":265},"obj":"http://purl.obolibrary.org/obo/CLO_0007701"},{"id":"T306","span":{"begin":271,"end":272},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"s extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. The residue was purified by flash column chromatography (silica gel, linear gradient 0–8% MeOH in DCM) to give 22 (321 mg, 93%) as a whit"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T775","span":{"begin":17,"end":20},"obj":"Chemical"},{"id":"T776","span":{"begin":102,"end":108},"obj":"Chemical"},{"id":"T777","span":{"begin":197,"end":203},"obj":"Chemical"},{"id":"T778","span":{"begin":230,"end":234},"obj":"Chemical"},{"id":"T779","span":{"begin":238,"end":241},"obj":"Chemical"}],"attributes":[{"id":"A775","pred":"chebi_id","subj":"T775","obj":"http://purl.obolibrary.org/obo/CHEBI_15767"},{"id":"A776","pred":"chebi_id","subj":"T776","obj":"http://purl.obolibrary.org/obo/CHEBI_32149"},{"id":"A777","pred":"chebi_id","subj":"T777","obj":"http://purl.obolibrary.org/obo/CHEBI_30563"},{"id":"A778","pred":"chebi_id","subj":"T778","obj":"http://purl.obolibrary.org/obo/CHEBI_17790"},{"id":"A779","pred":"chebi_id","subj":"T779","obj":"http://purl.obolibrary.org/obo/CHEBI_15767"}],"text":"s extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. The residue was purified by flash column chromatography (silica gel, linear gradient 0–8% MeOH in DCM) to give 22 (321 mg, 93%) as a whit"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T15","span":{"begin":17,"end":20},"obj":"Phenotype"},{"id":"T16","span":{"begin":238,"end":241},"obj":"Phenotype"}],"attributes":[{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0001644"},{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0001644"}],"text":"s extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. The residue was purified by flash column chromatography (silica gel, linear gradient 0–8% MeOH in DCM) to give 22 (321 mg, 93%) as a whit"}