PMC:7291971 / 40178-40714 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T835","span":{"begin":338,"end":347},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T836","span":{"begin":439,"end":444},"obj":"CHEBI:15377;CHEBI:15377"},{"id":"T837","span":{"begin":529,"end":533},"obj":"CHEBI:32145;CHEBI:32145"},{"id":"T98523","span":{"begin":338,"end":347},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T86450","span":{"begin":439,"end":444},"obj":"CHEBI:15377;CHEBI:15377"},{"id":"T52872","span":{"begin":529,"end":533},"obj":"CHEBI:32145;CHEBI:32145"}],"text":", CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: 828.4372, found: 828.4371.\n\n4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16\nThe synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. 0.14 M). After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), "}

{"project":"LitCovid-PubTator","denotations":[{"id":"690","span":{"begin":242,"end":256},"obj":"Chemical"},{"id":"691","span":{"begin":215,"end":219},"obj":"Disease"},{"id":"703","span":{"begin":432,"end":435},"obj":"Chemical"},{"id":"704","span":{"begin":439,"end":444},"obj":"Chemical"},{"id":"705","span":{"begin":529,"end":533},"obj":"Chemical"},{"id":"713","span":{"begin":521,"end":528},"obj":"Disease"}],"attributes":[{"id":"A703","pred":"tao:has_database_id","subj":"703","obj":"MESH:D014269"},{"id":"A704","pred":"tao:has_database_id","subj":"704","obj":"MESH:D014867"},{"id":"A713","pred":"tao:has_database_id","subj":"713","obj":"MESH:D002311"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":", CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: 828.4372, found: 828.4371.\n\n4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16\nThe synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. 0.14 M). After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T291","span":{"begin":258,"end":261},"obj":"http://purl.obolibrary.org/obo/CLO_0007706"},{"id":"T292","span":{"begin":351,"end":355},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T293","span":{"begin":485,"end":488},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"}],"text":", CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: 828.4372, found: 828.4371.\n\n4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16\nThe synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. 0.14 M). After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T703","span":{"begin":2,"end":7},"obj":"Chemical"},{"id":"T704","span":{"begin":432,"end":435},"obj":"Chemical"},{"id":"T705","span":{"begin":439,"end":444},"obj":"Chemical"},{"id":"T706","span":{"begin":525,"end":528},"obj":"Chemical"},{"id":"T707","span":{"begin":529,"end":533},"obj":"Chemical"}],"attributes":[{"id":"A703","pred":"chebi_id","subj":"T703","obj":"http://purl.obolibrary.org/obo/CHEBI_85365"},{"id":"A704","pred":"chebi_id","subj":"T704","obj":"http://purl.obolibrary.org/obo/CHEBI_45892"},{"id":"A705","pred":"chebi_id","subj":"T705","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A706","pred":"chebi_id","subj":"T706","obj":"http://purl.obolibrary.org/obo/CHEBI_15767"},{"id":"A707","pred":"chebi_id","subj":"T707","obj":"http://purl.obolibrary.org/obo/CHEBI_17790"}],"text":", CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: 828.4372, found: 828.4371.\n\n4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16\nThe synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. 0.14 M). After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), "}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T11","span":{"begin":525,"end":528},"obj":"Phenotype"}],"attributes":[{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0001644"}],"text":", CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: 828.4372, found: 828.4371.\n\n4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16\nThe synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. 0.14 M). After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T48","span":{"begin":325,"end":334},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T49","span":{"begin":372,"end":381},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":", CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: 828.4372, found: 828.4371.\n\n4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16\nThe synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. 0.14 M). After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), "}

{"project":"LitCovid-sentences","denotations":[{"id":"T295","span":{"begin":215,"end":264},"obj":"Sentence"},{"id":"T296","span":{"begin":265,"end":281},"obj":"Sentence"},{"id":"T297","span":{"begin":282,"end":291},"obj":"Sentence"},{"id":"T298","span":{"begin":293,"end":367},"obj":"Sentence"},{"id":"T299","span":{"begin":368,"end":456},"obj":"Sentence"},{"id":"T300","span":{"begin":457,"end":465},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":", CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: 828.4372, found: 828.4371.\n\n4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16\nThe synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. 0.14 M). After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), "}