PMC:7291971 / 35413-35683 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T728","span":{"begin":63,"end":72},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T729","span":{"begin":96,"end":104},"obj":"CHEBI:75958;CHEBI:75958"},{"id":"T730","span":{"begin":108,"end":111},"obj":"CHEBI:51231;CHEBI:51231"},{"id":"T731","span":{"begin":111,"end":116},"obj":"CHEBI:46882;CHEBI:46882"},{"id":"T732","span":{"begin":116,"end":117},"obj":"CHEBI:75508;CHEBI:75508"},{"id":"T733","span":{"begin":117,"end":121},"obj":"CHEBI:51231;CHEBI:51231"},{"id":"T734","span":{"begin":121,"end":137},"obj":"CHEBI:53250;CHEBI:53250"},{"id":"T735","span":{"begin":138,"end":147},"obj":"CHEBI:22260;CHEBI:22260"},{"id":"T736","span":{"begin":226,"end":245},"obj":"CHEBI:53325;CHEBI:53325"},{"id":"T737","span":{"begin":246,"end":254},"obj":"CHEBI:17996;CHEBI:17996"},{"id":"T2577","span":{"begin":63,"end":72},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T24815","span":{"begin":96,"end":104},"obj":"CHEBI:75958;CHEBI:75958"},{"id":"T614","span":{"begin":108,"end":111},"obj":"CHEBI:51231;CHEBI:51231"},{"id":"T19968","span":{"begin":111,"end":116},"obj":"CHEBI:46882;CHEBI:46882"},{"id":"T95384","span":{"begin":116,"end":117},"obj":"CHEBI:75508;CHEBI:75508"},{"id":"T33892","span":{"begin":117,"end":121},"obj":"CHEBI:51231;CHEBI:51231"},{"id":"T55720","span":{"begin":121,"end":137},"obj":"CHEBI:53250;CHEBI:53250"},{"id":"T41124","span":{"begin":138,"end":147},"obj":"CHEBI:22260;CHEBI:22260"},{"id":"T59013","span":{"begin":226,"end":245},"obj":"CHEBI:53325;CHEBI:53325"},{"id":"T59951","span":{"begin":246,"end":254},"obj":"CHEBI:17996;CHEBI:17996"}],"text":"any degradation.\n\n4.1.2 General method A for the synthesis of compounds 18, 26, 27 and 29\nTo a solution of 5′-amino-2′,3′-isopropylidene adenosine in anhydrous DMF (conc. 0.2 M) was added Et3N (2.00 eq) and the corresponding nitrobenzenesufonyl chloride (1.50 eq) at 0 "}

{"project":"LitCovid-PubTator","denotations":[{"id":"580","span":{"begin":108,"end":137},"obj":"Chemical"},{"id":"581","span":{"begin":138,"end":147},"obj":"Chemical"},{"id":"582","span":{"begin":161,"end":164},"obj":"Chemical"},{"id":"583","span":{"begin":189,"end":193},"obj":"Chemical"},{"id":"584","span":{"begin":226,"end":254},"obj":"Chemical"}],"attributes":[{"id":"A581","pred":"tao:has_database_id","subj":"581","obj":"MESH:D000241"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"any degradation.\n\n4.1.2 General method A for the synthesis of compounds 18, 26, 27 and 29\nTo a solution of 5′-amino-2′,3′-isopropylidene adenosine in anhydrous DMF (conc. 0.2 M) was added Et3N (2.00 eq) and the corresponding nitrobenzenesufonyl chloride (1.50 eq) at 0 "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T265","span":{"begin":40,"end":41},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T266","span":{"begin":73,"end":75},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T267","span":{"begin":81,"end":83},"obj":"http://purl.obolibrary.org/obo/CLO_0050509"},{"id":"T268","span":{"begin":94,"end":95},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"any degradation.\n\n4.1.2 General method A for the synthesis of compounds 18, 26, 27 and 29\nTo a solution of 5′-amino-2′,3′-isopropylidene adenosine in anhydrous DMF (conc. 0.2 M) was added Et3N (2.00 eq) and the corresponding nitrobenzenesufonyl chloride (1.50 eq) at 0 "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T576","span":{"begin":96,"end":104},"obj":"Chemical"},{"id":"T577","span":{"begin":111,"end":116},"obj":"Chemical"},{"id":"T578","span":{"begin":123,"end":137},"obj":"Chemical"},{"id":"T579","span":{"begin":138,"end":147},"obj":"Chemical"},{"id":"T580","span":{"begin":161,"end":164},"obj":"Chemical"},{"id":"T581","span":{"begin":246,"end":254},"obj":"Chemical"}],"attributes":[{"id":"A576","pred":"chebi_id","subj":"T576","obj":"http://purl.obolibrary.org/obo/CHEBI_75958"},{"id":"A577","pred":"chebi_id","subj":"T577","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A578","pred":"chebi_id","subj":"T578","obj":"http://purl.obolibrary.org/obo/CHEBI_29858"},{"id":"A579","pred":"chebi_id","subj":"T579","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"},{"id":"A580","pred":"chebi_id","subj":"T580","obj":"http://purl.obolibrary.org/obo/CHEBI_17741"},{"id":"A581","pred":"chebi_id","subj":"T581","obj":"http://purl.obolibrary.org/obo/CHEBI_17996"}],"text":"any degradation.\n\n4.1.2 General method A for the synthesis of compounds 18, 26, 27 and 29\nTo a solution of 5′-amino-2′,3′-isopropylidene adenosine in anhydrous DMF (conc. 0.2 M) was added Et3N (2.00 eq) and the corresponding nitrobenzenesufonyl chloride (1.50 eq) at 0 "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T45","span":{"begin":4,"end":15},"obj":"http://purl.obolibrary.org/obo/GO_0009056"},{"id":"T46","span":{"begin":50,"end":59},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"any degradation.\n\n4.1.2 General method A for the synthesis of compounds 18, 26, 27 and 29\nTo a solution of 5′-amino-2′,3′-isopropylidene adenosine in anhydrous DMF (conc. 0.2 M) was added Et3N (2.00 eq) and the corresponding nitrobenzenesufonyl chloride (1.50 eq) at 0 "}

{"project":"LitCovid-sentences","denotations":[{"id":"T260","span":{"begin":18,"end":90},"obj":"Sentence"},{"id":"T261","span":{"begin":91,"end":171},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"any degradation.\n\n4.1.2 General method A for the synthesis of compounds 18, 26, 27 and 29\nTo a solution of 5′-amino-2′,3′-isopropylidene adenosine in anhydrous DMF (conc. 0.2 M) was added Et3N (2.00 eq) and the corresponding nitrobenzenesufonyl chloride (1.50 eq) at 0 "}