PMC:7291971 / 34219-89056
Annnotations
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T720 | 75-83 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T721 | 88-96 | CHEBI:33893;CHEBI:33893 | denotes | reagents |
| T722 | 206-213 | CHEBI:29320;CHEBI:29320 | denotes | calcium |
| T723 | 214-221 | CHEBI:29239;CHEBI:29239 | denotes | hydride |
| T724 | 284-290 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T725 | 952-959 | CHEBI:46787;CHEBI:46787 | denotes | solvent |
| T726 | 1021-1026 | CHEBI:1418;CHEBI:1418 | denotes | CH3CN |
| T727 | 1130-1139 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T728 | 1257-1266 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T729 | 1290-1298 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T730 | 1302-1305 | CHEBI:51231;CHEBI:51231 | denotes | 5′- |
| T731 | 1305-1310 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T732 | 1310-1311 | CHEBI:75508;CHEBI:75508 | denotes | - |
| T733 | 1311-1315 | CHEBI:51231;CHEBI:51231 | denotes | 2′,3 |
| T734 | 1315-1331 | CHEBI:53250;CHEBI:53250 | denotes | ′-isopropylidene |
| T735 | 1332-1341 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T736 | 1420-1439 | CHEBI:53325;CHEBI:53325 | denotes | nitrobenzenesufonyl |
| T737 | 1440-1448 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T738 | 1481-1488 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T739 | 1584-1591 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T740 | 1692-1698 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T741 | 1795-1803 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T742 | 1874-1906 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T743 | 1910-1911 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T744 | 1911-1913 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T745 | 1913-1926 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T746 | 1926-1932 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T747 | 1934-1936 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T748 | 1936-1948 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T749 | 1948-1951 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T750 | 1951-1962 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T751 | 1992-1993 | CHEBI:75508;CHEBI:75508 | denotes | 5 |
| T752 | 1993-1994 | CHEBI:82321;CHEBI:82321 | denotes | ′ |
| T753 | 1994-1995 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T754 | 1995-2000 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T755 | 2000-2002 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T756 | 2002-2021 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T757 | 2022-2031 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T758 | 2065-2086 | CHEBI:86228;CHEBI:86228 | denotes | 4-nitrobenzenesufonyl |
| T759 | 2087-2095 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T760 | 2159-2163 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T761 | 2487-2490 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T762 | 2748-2757 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T763 | 2773-2781 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T764 | 2883-2888 | CHEBI:32031;CHEBI:32031 | denotes | K2CO3 |
| T765 | 2984-2989 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T766 | 2995-3002 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T767 | 3103-3109 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T768 | 3198-3204 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T769 | 3231-3235 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T770 | 3264-3272 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T771 | 3341-3360 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T772 | 3361-3363 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T773 | 3368-3371 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T774 | 3372-3373 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T775 | 3377-3378 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T776 | 3378-3380 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T777 | 3380-3393 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T778 | 3450-3451 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T779 | 3451-3469 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T780 | 3470-3473 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T781 | 3474-3478 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T782 | 3479-3485 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T783 | 3485-3503 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T784 | 3503-3504 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T785 | 3504-3507 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T786 | 3508-3514 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T787 | 3515-3527 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T788 | 3527-3530 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T789 | 3537-3540 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T790 | 3540-3552 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T791 | 3552-3555 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T792 | 3555-3566 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T793 | 3699-3703 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T794 | 3727-3732 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T795 | 4231-4234 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T796 | 4622-4624 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T797 | 4625-4635 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T798 | 4636-4660 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T799 | 4661-4663 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T800 | 4679-4681 | CHEBI:53233;CHEBI:53233 | denotes | 3] |
| T801 | 4681-4687 | CHEBI:82321;CHEBI:82321 | denotes | dioxol |
| T802 | 4687-4693 | CHEBI:53233;CHEBI:53233 | denotes | -4-yl] |
| T803 | 4693-4699 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T804 | 4699-4700 | CHEBI:53233;CHEBI:53233 | denotes | } |
| T805 | 4700-4705 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T806 | 4706-4712 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T807 | 4714-4742 | CHEBI:53233;CHEBI:53233 | denotes | 4-[(tert-butyldimethylsilyl) |
| T808 | 4742-4745 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T809 | 4747-4748 | CHEBI:53233;CHEBI:53233 | denotes | 5 |
| T810 | 4756-4757 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T811 | 4757-4775 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T812 | 4776-4779 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T813 | 4780-4786 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T814 | 4787-4793 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T815 | 4793-4794 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T816 | 4794-4799 | CHEBI:53233;CHEBI:53233 | denotes | 2-yl] |
| T817 | 4800-4802 | CHEBI:53233;CHEBI:53233 | denotes | 9H |
| T818 | 4802-4808 | CHEBI:35589;CHEBI:35589 | denotes | -purin |
| T819 | 4809-4810 | CHEBI:53233;CHEBI:53233 | denotes | 6 |
| T820 | 4811-4816 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T821 | 4827-4835 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T822 | 4906-4911 | CHEBI:32031;CHEBI:32031 | denotes | K2CO3 |
| T823 | 4944-4954 | CHEBI:48498;CHEBI:48498 | denotes | thiophenol |
| T824 | 5053-5060 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T825 | 5110-5117 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T826 | 5118-5122 | CHEBI:32145;CHEBI:32145 | denotes | NaOH |
| T827 | 5123-5131 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T828 | 5145-5152 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T829 | 5263-5269 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T830 | 5358-5364 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T831 | 5392-5396 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T832 | 5476-5480 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T833 | 5504-5509 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T834 | 5943-5946 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T835 | 6297-6306 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T836 | 6398-6403 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T837 | 6488-6492 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T838 | 6495-6503 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T839 | 6571-6574 | CHEBI:62946;CHEBI:62946 | denotes | NH3 |
| T840 | 6578-6582 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T841 | 6660-6666 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T842 | 6721-6733 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T843 | 6797-6805 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T844 | 6853-6858 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T845 | 6859-6866 | CHEBI:46923;CHEBI:46923 | denotes | dioxane |
| T846 | 6883-6891 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T847 | 6968-6969 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T848 | 6974-6977 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T849 | 6978-6988 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T850 | 6990-6992 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T851 | 6992-6999 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T852 | 7003-7016 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T853 | 7017-7023 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T854 | 7023-7028 | CHEBI:15533;CHEBI:15533 | denotes | -3-yl |
| T855 | 7028-7029 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T856 | 7029-7032 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T857 | 7033-7038 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T858 | 7039-7044 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T859 | 7045-7051 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T860 | 7052-7059 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T861 | 7059-7060 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T862 | 7060-7064 | CHEBI:82321;CHEBI:82321 | denotes | 3,4- |
| T863 | 7064-7068 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T864 | 7160-7172 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T865 | 7704-7707 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T866 | 8009-8010 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T867 | 8010-8014 | CHEBI:52029;CHEBI:52029 | denotes | 2,2- |
| T868 | 8014-8023 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl- |
| T869 | 8023-8033 | CHEBI:52029;CHEBI:52029 | denotes | tetrahydro |
| T870 | 8033-8036 | CHEBI:53233;CHEBI:53233 | denotes | -2H |
| T871 | 8050-8053 | CHEBI:52029;CHEBI:52029 | denotes | 1,3 |
| T872 | 8053-8054 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T873 | 8054-8060 | CHEBI:52029;CHEBI:52029 | denotes | dioxol |
| T874 | 8060-8065 | CHEBI:53233;CHEBI:53233 | denotes | -4-yl |
| T875 | 8112-8121 | CHEBI:53233;CHEBI:53233 | denotes | 4-[(tert- |
| T876 | 8121-8139 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T877 | 8139-8140 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T878 | 8140-8143 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T879 | 8143-8155 | CHEBI:53233;CHEBI:53233 | denotes | ]-5-{[(tert- |
| T880 | 8155-8173 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T881 | 8173-8174 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T882 | 8174-8177 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T883 | 8177-8178 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T884 | 8178-8184 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T885 | 8184-8185 | CHEBI:53233;CHEBI:53233 | denotes | } |
| T886 | 8185-8191 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T887 | 8191-8196 | CHEBI:53233;CHEBI:53233 | denotes | -3-yl |
| T888 | 8197-8200 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T889 | 8201-8206 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T890 | 8207-8212 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T891 | 8227-8233 | CHEBI:75508;CHEBI:75508 | denotes | butoxy |
| T892 | 8234-8242 | CHEBI:23019;CHEBI:23019 | denotes | carbonyl |
| T893 | 8243-8248 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T894 | 8249-8258 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T895 | 8269-8277 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T896 | 8347-8355 | CHEBI:17478;CHEBI:17478 | denotes | aldehyde |
| T897 | 8416-8427 | CHEBI:15366;CHEBI:15366 | denotes | acetic acid |
| T898 | 8516-8522 | CHEBI:35607;CHEBI:35607 | denotes | sodium |
| T899 | 8523-8544 | CHEBI:28621;CHEBI:28621 | denotes | triacetoxyborohydride |
| T900 | 8622-8629 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T901 | 8685-8692 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T902 | 8693-8699 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T903 | 8713-8720 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T904 | 8831-8837 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T905 | 8926-8932 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T906 | 8959-8963 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T907 | 9024-9028 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T908 | 9057-9062 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T909 | 9588-9591 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T910 | 10008-10027 | CHEBI:53233;CHEBI:53233 | denotes | 3,4-dihydroxyoxolan |
| T911 | 10030-10032 | CHEBI:53233;CHEBI:53233 | denotes | yl |
| T912 | 10064-10066 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T913 | 10067-10077 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T914 | 10079-10081 | CHEBI:17500;CHEBI:17500 | denotes | 4- |
| T915 | 10081-10088 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T916 | 10089-10090 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T917 | 10090-10092 | CHEBI:17500;CHEBI:17500 | denotes | -( |
| T918 | 10092-10105 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T919 | 10106-10112 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T920 | 10112-10113 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T921 | 10113-10114 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T922 | 10114-10117 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T923 | 10118-10121 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T924 | 10122-10127 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T925 | 10135-10155 | CHEBI:86228;CHEBI:86228 | denotes | 2-azaniumylbutanoate |
| T926 | 10169-10171 | CHEBI:53424;CHEBI:53424 | denotes | 22 |
| T927 | 10253-10258 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T928 | 10293-10301 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T929 | 10358-10363 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T930 | 10381-10388 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T931 | 10389-10393 | CHEBI:48607;CHEBI:48607 | denotes | LiOH |
| T932 | 10394-10402 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T933 | 10500-10507 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T934 | 10508-10511 | CHEBI:17883;CHEBI:17883 | denotes | HCl |
| T935 | 10512-10520 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T936 | 10526-10533 | CHEBI:46787;CHEBI:46787 | denotes | solvent |
| T937 | 10639-10645 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T938 | 10706-10718 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T939 | 10782-10790 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T940 | 10838-10843 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T941 | 11375-11378 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T942 | 11699-11704 | CHEBI:30756;CHEBI:30756 | denotes | -9-yl |
| T943 | 11705-11731 | CHEBI:53233;CHEBI:53233 | denotes | -3,4-dihydroxyoxolan-2-yl] |
| T944 | 11731-11737 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T945 | 11754-11775 | CHEBI:30756;CHEBI:30756 | denotes | 6-amino-9H-purin-9-yl |
| T946 | 11777-11779 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T947 | 11779-11786 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T948 | 11786-11787 | CHEBI:17500;CHEBI:17500 | denotes | - |
| T949 | 11787-11789 | CHEBI:34018;CHEBI:34018 | denotes | 5- |
| T950 | 11789-11790 | CHEBI:17500;CHEBI:17500 | denotes | ( |
| T951 | 11790-11803 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T952 | 11804-11810 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T953 | 11811-11812 | CHEBI:17500;CHEBI:17500 | denotes | 3 |
| T954 | 11816-11819 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T955 | 11820-11825 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T956 | 11826-11831 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T957 | 11832-11841 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T958 | 11933-11945 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T959 | 12629-12632 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T960 | 12948-12952 | CHEBI:30756;CHEBI:30756 | denotes | 9-yl |
| T961 | 12954-12978 | CHEBI:53233;CHEBI:53233 | denotes | 3,4-dihydroxyoxolan-2-yl |
| T962 | 12979-12985 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T963 | 13002-13023 | CHEBI:30756;CHEBI:30756 | denotes | 6-amino-9H-purin-9-yl |
| T964 | 13025-13027 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T965 | 13027-13034 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T966 | 13034-13035 | CHEBI:82321;CHEBI:82321 | denotes | - |
| T967 | 13035-13036 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T968 | 13036-13037 | CHEBI:82321;CHEBI:82321 | denotes | - |
| T969 | 13037-13038 | CHEBI:17500;CHEBI:17500 | denotes | ( |
| T970 | 13038-13051 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T971 | 13052-13058 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T972 | 13058-13059 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T973 | 13059-13063 | CHEBI:82321;CHEBI:82321 | denotes | 3-yl |
| T974 | 13064-13067 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T975 | 13068-13073 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T976 | 13080-13090 | CHEBI:22965;CHEBI:22965 | denotes | butanamide |
| T977 | 13104-13106 | CHEBI:53424;CHEBI:53424 | denotes | 22 |
| T978 | 13190-13195 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T979 | 13250-13258 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T980 | 13309-13312 | CHEBI:62946;CHEBI:62946 | denotes | NH3 |
| T981 | 13316-13320 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T982 | 13364-13372 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T983 | 13466-13472 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T984 | 13533-13545 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T985 | 13609-13617 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T986 | 13665-13670 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T987 | 14230-14233 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T988 | 14540-14549 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T989 | 14569-14577 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T990 | 14644-14651 | CHEBI:15858;CHEBI:15858 | denotes | bromide |
| T991 | 14652-14659 | CHEBI:33893;CHEBI:33893 | denotes | reagent |
| T992 | 14754-14761 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T993 | 14800-14807 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T994 | 14908-14914 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T995 | 15003-15009 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T996 | 15036-15040 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T997 | 15069-15077 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T998 | 15147-15149 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T999 | 15150-15160 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1000 | 15161-15185 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T1001 | 15186-15188 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1002 | 15204-15212 | CHEBI:53233;CHEBI:53233 | denotes | 3]dioxol |
| T1003 | 15213-15214 | CHEBI:53233;CHEBI:53233 | denotes | 4 |
| T1004 | 15214-15217 | CHEBI:28714;CHEBI:28714 | denotes | -yl |
| T1005 | 15218-15224 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1006 | 15226-15231 | CHEBI:34594;CHEBI:34594 | denotes | butyl |
| T1007 | 15232-15237 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1008 | 15238-15244 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T1009 | 15246-15247 | CHEBI:53233;CHEBI:53233 | denotes | 4 |
| T1010 | 15255-15273 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1011 | 15274-15277 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1012 | 15308-15311 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1013 | 15312-15318 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1014 | 15319-15325 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1015 | 15325-15326 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1016 | 15326-15331 | CHEBI:53233;CHEBI:53233 | denotes | 2-yl] |
| T1017 | 15332-15334 | CHEBI:53233;CHEBI:53233 | denotes | 9H |
| T1018 | 15335-15340 | CHEBI:35589;CHEBI:35589 | denotes | purin |
| T1019 | 15343-15348 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T1020 | 15411-15424 | CHEBI:20067;CHEBI:20067 | denotes | 1-bromobutane |
| T1021 | 15482-15486 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1022 | 15515-15520 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1023 | 16115-16118 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1024 | 16499-16501 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T1025 | 16502-16512 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1026 | 16513-16537 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T1027 | 16538-16540 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1028 | 16556-16570 | CHEBI:53233;CHEBI:53233 | denotes | 3]dioxol-4-yl] |
| T1029 | 16570-16576 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1030 | 16578-16579 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1031 | 16579-16593 | CHEBI:8502;CHEBI:8502 | denotes | -phenylpropyl) |
| T1032 | 16593-16598 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1033 | 16599-16605 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T1034 | 16606-16609 | CHEBI:53233;CHEBI:53233 | denotes | -4- |
| T1035 | 16635-16638 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1036 | 16640-16645 | CHEBI:53233;CHEBI:53233 | denotes | 5-{[( |
| T1037 | 16649-16650 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1038 | 16650-16668 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1039 | 16668-16669 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1040 | 16669-16672 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1041 | 16673-16679 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1042 | 16680-16686 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1043 | 16686-16689 | CHEBI:53233;CHEBI:53233 | denotes | -2- |
| T1044 | 16689-16691 | CHEBI:82321;CHEBI:82321 | denotes | yl |
| T1045 | 16691-16693 | CHEBI:53233;CHEBI:53233 | denotes | ]- |
| T1046 | 16693-16695 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T1047 | 16695-16701 | CHEBI:35589;CHEBI:35589 | denotes | -purin |
| T1048 | 16704-16709 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T1049 | 16775-16776 | CHEBI:17824;CHEBI:17824 | denotes | 1 |
| T1050 | 16776-16777 | CHEBI:8502;CHEBI:8502 | denotes | - |
| T1051 | 16777-16782 | CHEBI:47265;CHEBI:47265 | denotes | bromo |
| T1052 | 16782-16798 | CHEBI:17824;CHEBI:17824 | denotes | -3-phenylpropane |
| T1053 | 16856-16860 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1054 | 16888-16893 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1055 | 17475-17478 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1056 | 17493-17498 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1057 | 17891-17923 | CHEBI:53233;CHEBI:53233 | denotes | 2-dimethyl-tetrahydro-2H-furo[3, |
| T1058 | 17924-17925 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1059 | 17929-17930 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1060 | 17930-17932 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1061 | 17932-17933 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T1062 | 17933-17939 | CHEBI:52029;CHEBI:52029 | denotes | dioxol |
| T1063 | 17939-17945 | CHEBI:53233;CHEBI:53233 | denotes | -4-yl] |
| T1064 | 17945-17951 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1065 | 17995-18000 | CHEBI:53233;CHEBI:53233 | denotes | tert- |
| T1066 | 18000-18018 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1067 | 18018-18019 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1068 | 18019-18022 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1069 | 18022-18027 | CHEBI:53233;CHEBI:53233 | denotes | ]-5-{ |
| T1070 | 18028-18034 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T1071 | 18034-18052 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T1072 | 18052-18053 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1073 | 18053-18056 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1074 | 18057-18063 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1075 | 18064-18070 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1076 | 18070-18076 | CHEBI:53233;CHEBI:53233 | denotes | -3-yl] |
| T1077 | 18076-18079 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1078 | 18080-18085 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1079 | 18092-18101 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T1080 | 18248-18252 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1081 | 18281-18286 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1082 | 18879-18882 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1083 | 19287-19288 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T1084 | 19293-19296 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T1085 | 19297-19307 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1086 | 19309-19311 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T1087 | 19311-19318 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1088 | 19322-19335 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1089 | 19336-19342 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1090 | 19342-19343 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1091 | 19343-19344 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1092 | 19344-19345 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1093 | 19345-19348 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T1094 | 19348-19351 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1095 | 19352-19357 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1096 | 19359-19364 | CHEBI:34594;CHEBI:34594 | denotes | butyl |
| T1097 | 19365-19370 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1098 | 19371-19377 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1099 | 19378-19385 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T1100 | 19386-19390 | CHEBI:53233;CHEBI:53233 | denotes | 3,4- |
| T1101 | 19390-19394 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T1102 | 19484-19496 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1103 | 19660-19664 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T1104 | 20189-20192 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1105 | 20522-20523 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T1106 | 20528-20531 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T1107 | 20532-20542 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1108 | 20544-20546 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T1109 | 20546-20553 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1110 | 20557-20570 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1111 | 20571-20577 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1112 | 20577-20578 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1113 | 20578-20583 | CHEBI:53233;CHEBI:53233 | denotes | 3-yl] |
| T1114 | 20583-20586 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1115 | 20587-20592 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1116 | 20594-20596 | CHEBI:17824;CHEBI:17824 | denotes | 3- |
| T1117 | 20596-20608 | CHEBI:8102;CHEBI:8102 | denotes | phenylpropyl |
| T1118 | 20609-20614 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1119 | 20615-20621 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1120 | 20622-20629 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T1121 | 20630-20634 | CHEBI:53233;CHEBI:53233 | denotes | 3,4- |
| T1122 | 20634-20638 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T1123 | 20729-20741 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1124 | 21434-21437 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1125 | 21760-21777 | CHEBI:53233;CHEBI:53233 | denotes | 4-dihydroxyoxolan |
| T1126 | 21778-21779 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T1127 | 21780-21782 | CHEBI:53233;CHEBI:53233 | denotes | yl |
| T1128 | 21783-21789 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1129 | 21814-21816 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T1130 | 21817-21827 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1131 | 21829-21831 | CHEBI:17500;CHEBI:17500 | denotes | 4- |
| T1132 | 21831-21838 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1133 | 21838-21839 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1134 | 21839-21840 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T1135 | 21840-21841 | CHEBI:17500;CHEBI:17500 | denotes | - |
| T1136 | 21841-21842 | CHEBI:62946;CHEBI:62946 | denotes | ( |
| T1137 | 21842-21855 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1138 | 21856-21862 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1139 | 21862-21868 | CHEBI:15533;CHEBI:15533 | denotes | -3-yl] |
| T1140 | 21868-21871 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1141 | 21872-21877 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1142 | 21878-21883 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1143 | 21884-21893 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T1144 | 21985-21997 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1145 | 22691-22694 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1146 | 23019-23034 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T1147 | 23037-23039 | CHEBI:53233;CHEBI:53233 | denotes | yl |
| T1148 | 23040-23046 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1149 | 23079-23083 | CHEBI:30756;CHEBI:30756 | denotes | 9-yl |
| T1150 | 23084-23086 | CHEBI:17500;CHEBI:17500 | denotes | -4 |
| T1151 | 23086-23087 | CHEBI:34018;CHEBI:34018 | denotes | - |
| T1152 | 23087-23094 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1153 | 23094-23098 | CHEBI:17500;CHEBI:17500 | denotes | -5-( |
| T1154 | 23098-23111 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1155 | 23112-23118 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1156 | 23118-23124 | CHEBI:15533;CHEBI:15533 | denotes | -3-yl] |
| T1157 | 23124-23127 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1158 | 23128-23133 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1159 | 23134-23139 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1160 | 23140-23153 | CHEBI:30772;CHEBI:30772 | denotes | butanoic acid |
| T1161 | 23234-23239 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T1162 | 23277-23285 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T1163 | 23342-23347 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T1164 | 23365-23369 | CHEBI:48607;CHEBI:48607 | denotes | LiOH |
| T1165 | 23370-23377 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1166 | 23378-23386 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1167 | 23488-23491 | CHEBI:17883;CHEBI:17883 | denotes | HCl |
| T1168 | 23492-23499 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1169 | 23500-23508 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1170 | 23510-23518 | CHEBI:46787;CHEBI:46787 | denotes | Solvents |
| T1171 | 23625-23631 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T1172 | 23692-23704 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1173 | 23768-23776 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T1174 | 23824-23829 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T1175 | 23834-23845 | CHEBI:47032;CHEBI:47032 | denotes | 1,4-dioxane |
| T1176 | 24353-24356 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1177 | 24668-24683 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T1178 | 24684-24685 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T1179 | 24686-24689 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T1180 | 24689-24695 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1181 | 24726-24736 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1182 | 24738-24740 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T1183 | 24740-24747 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1184 | 24748-24749 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T1185 | 24751-24764 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1186 | 24765-24771 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1187 | 24771-24772 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1188 | 24772-24773 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1189 | 24773-24776 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T1190 | 24776-24777 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T1191 | 24777-24780 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1192 | 24790-24802 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1193 | 24802-24805 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1194 | 24805-24816 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1195 | 24904-24916 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1196 | 25513-25516 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1197 | 25839-25871 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T1198 | 25875-25876 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1199 | 25876-25878 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1200 | 25878-25891 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1201 | 25891-25897 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1202 | 25899-25901 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T1203 | 25901-25908 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1204 | 25908-25911 | CHEBI:86228;CHEBI:86228 | denotes | -2- |
| T1205 | 25911-25923 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1206 | 25923-25926 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1207 | 25926-25937 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1208 | 25967-25969 | CHEBI:75508;CHEBI:75508 | denotes | 5′ |
| T1209 | 25969-25970 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T1210 | 25970-25975 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1211 | 25975-25977 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T1212 | 25977-25996 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T1213 | 25997-26006 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T1214 | 26040-26042 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T1215 | 26042-26049 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1216 | 26049-26071 | CHEBI:86228;CHEBI:86228 | denotes | -2-nitrobenzenesufonyl |
| T1217 | 26072-26080 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T1218 | 26144-26148 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1219 | 26551-26554 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1220 | 26837-26869 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T1221 | 26873-26874 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1222 | 26874-26876 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1223 | 26876-26889 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1224 | 26899-26906 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1225 | 26906-26909 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1226 | 26909-26921 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1227 | 26921-26924 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1228 | 26924-26935 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1229 | 26965-26967 | CHEBI:75508;CHEBI:75508 | denotes | 5′ |
| T1230 | 26967-26968 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T1231 | 26968-26973 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1232 | 26973-26975 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T1233 | 26975-26994 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T1234 | 26995-27004 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T1235 | 27038-27040 | CHEBI:86228;CHEBI:86228 | denotes | 2- |
| T1236 | 27040-27047 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1237 | 27047-27069 | CHEBI:86228;CHEBI:86228 | denotes | -4-nitrobenzenesufonyl |
| T1238 | 27070-27078 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T1239 | 27142-27146 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1240 | 27516-27519 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1241 | 27802-27834 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T1242 | 27838-27839 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1243 | 27839-27841 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1244 | 27841-27854 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1245 | 27864-27869 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T1246 | 27869-27872 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1247 | 27872-27896 | CHEBI:36810;CHEBI:36810 | denotes | (trifluoromethyl)benzene |
| T1248 | 27896-27897 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T1249 | 27897-27899 | CHEBI:86228;CHEBI:86228 | denotes | 1- |
| T1250 | 27899-27910 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1251 | 27921-27929 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1252 | 27933-27934 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T1253 | 27934-27935 | CHEBI:53250;CHEBI:53250 | denotes | ′ |
| T1254 | 27935-27936 | CHEBI:75508;CHEBI:75508 | denotes | - |
| T1255 | 27936-27941 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1256 | 27941-27942 | CHEBI:75508;CHEBI:75508 | denotes | - |
| T1257 | 27942-27962 | CHEBI:53250;CHEBI:53250 | denotes | 2′,3′-isopropylidene |
| T1258 | 27963-27972 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T1259 | 28073-28075 | CHEBI:86228;CHEBI:86228 | denotes | 2- |
| T1260 | 28075-28080 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T1261 | 28080-28112 | CHEBI:86228;CHEBI:86228 | denotes | -4-trifluoromethylbenzenesufonyl |
| T1262 | 28113-28121 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T1263 | 28186-28193 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T1264 | 28240-28245 | CHEBI:2511;CHEBI:2511 | denotes | argon |
| T1265 | 28260-28267 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T1266 | 28303-28308 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T1267 | 28322-28329 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1268 | 28450-28456 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T1269 | 28545-28551 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T1270 | 28578-28582 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1271 | 28651-28655 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1272 | 29043-29046 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1273 | 29388-29420 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T1274 | 29424-29425 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1275 | 29425-29427 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1276 | 29427-29440 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1277 | 29440-29446 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1278 | 29448-29450 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T1279 | 29450-29456 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T1280 | 29456-29459 | CHEBI:86228;CHEBI:86228 | denotes | -3- |
| T1281 | 29459-29471 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1282 | 29471-29474 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1283 | 29474-29485 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1284 | 29515-29517 | CHEBI:75508;CHEBI:75508 | denotes | 5′ |
| T1285 | 29517-29518 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T1286 | 29518-29523 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1287 | 29523-29525 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T1288 | 29525-29544 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T1289 | 29545-29554 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T1290 | 29588-29590 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T1291 | 29590-29596 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T1292 | 29596-29618 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrobenzenesufonyl |
| T1293 | 29619-29627 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T1294 | 29691-29695 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1295 | 30074-30077 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1296 | 30363-30382 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T1297 | 30383-30385 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1298 | 30390-30393 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T1299 | 30394-30395 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1300 | 30399-30400 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1301 | 30400-30402 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1302 | 30402-30415 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1303 | 30472-30473 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1304 | 30473-30491 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1305 | 30492-30495 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1306 | 30496-30500 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T1307 | 30501-30507 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T1308 | 30507-30525 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T1309 | 30525-30526 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1310 | 30526-30529 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1311 | 30530-30536 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1312 | 30537-30549 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T1313 | 30549-30552 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1314 | 30559-30562 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1315 | 30562-30569 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1316 | 30569-30572 | CHEBI:86228;CHEBI:86228 | denotes | -2- |
| T1317 | 30572-30584 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1318 | 30584-30587 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1319 | 30587-30598 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1320 | 30729-30733 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1321 | 30757-30762 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1322 | 31322-31325 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1323 | 31731-31750 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T1324 | 31751-31753 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1325 | 31758-31761 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T1326 | 31762-31763 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1327 | 31767-31768 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1328 | 31768-31770 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1329 | 31770-31783 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1330 | 31840-31841 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1331 | 31841-31859 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1332 | 31860-31863 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1333 | 31864-31868 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T1334 | 31869-31875 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T1335 | 31875-31893 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T1336 | 31893-31894 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1337 | 31894-31897 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1338 | 31898-31904 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1339 | 31905-31917 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T1340 | 31917-31920 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1341 | 31927-31930 | CHEBI:86228;CHEBI:86228 | denotes | -2- |
| T1342 | 31930-31937 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1343 | 31937-31940 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1344 | 31940-31952 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1345 | 31952-31955 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1346 | 31955-31966 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1347 | 32097-32101 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1348 | 32125-32130 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1349 | 32606-32609 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1350 | 33014-33033 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T1351 | 33034-33036 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1352 | 33041-33044 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T1353 | 33045-33046 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1354 | 33050-33051 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1355 | 33051-33053 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1356 | 33053-33066 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1357 | 33123-33124 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1358 | 33124-33142 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1359 | 33143-33146 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1360 | 33147-33151 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T1361 | 33152-33158 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T1362 | 33158-33176 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T1363 | 33176-33177 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1364 | 33177-33180 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1365 | 33181-33187 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1366 | 33188-33200 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T1367 | 33200-33203 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1368 | 33211-33213 | CHEBI:86228;CHEBI:86228 | denotes | 2- |
| T1369 | 33213-33218 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T1370 | 33218-33221 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1371 | 33221-33245 | CHEBI:36810;CHEBI:36810 | denotes | (trifluoromethyl)benzene |
| T1372 | 33245-33246 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T1373 | 33246-33248 | CHEBI:86228;CHEBI:86228 | denotes | 1- |
| T1374 | 33248-33259 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1375 | 33388-33392 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1376 | 33416-33421 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1377 | 34010-34013 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1378 | 34500-34519 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T1379 | 34520-34522 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1380 | 34527-34530 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T1381 | 34531-34532 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1382 | 34536-34537 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1383 | 34537-34539 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1384 | 34539-34552 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1385 | 34609-34610 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1386 | 34610-34628 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1387 | 34629-34632 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1388 | 34633-34637 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T1389 | 34638-34644 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T1390 | 34644-34662 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T1391 | 34662-34663 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1392 | 34663-34666 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1393 | 34667-34673 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1394 | 34674-34686 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T1395 | 34686-34689 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1396 | 34696-34699 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1397 | 34699-34705 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T1398 | 34705-34708 | CHEBI:86228;CHEBI:86228 | denotes | -3- |
| T1399 | 34708-34720 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1400 | 34720-34723 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1401 | 34723-34734 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1402 | 34865-34869 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1403 | 34893-34898 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1404 | 35413-35416 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1405 | 35820-35821 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1406 | 35821-35822 | CHEBI:34018;CHEBI:34018 | denotes | , |
| T1407 | 35822-35824 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T1408 | 35824-35848 | CHEBI:47019;CHEBI:47019 | denotes | dihydroxytetrahydrofuran |
| T1409 | 35849-35853 | CHEBI:53233;CHEBI:53233 | denotes | 2-yl |
| T1410 | 35854-35860 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1411 | 35883-35886 | CHEBI:34018;CHEBI:34018 | denotes | 2-( |
| T1412 | 35886-35907 | CHEBI:30756;CHEBI:30756 | denotes | 6-amino-9H-purin-9-yl |
| T1413 | 35908-35911 | CHEBI:34018;CHEBI:34018 | denotes | -4- |
| T1414 | 35911-35918 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1415 | 35918-35922 | CHEBI:34018;CHEBI:34018 | denotes | -5-( |
| T1416 | 35922-35935 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1417 | 35936-35951 | CHEBI:27902;CHEBI:27902 | denotes | tetrahydrofuran |
| T1418 | 35951-35952 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1419 | 35952-35953 | CHEBI:34018;CHEBI:34018 | denotes | 3 |
| T1420 | 35953-35956 | CHEBI:53233;CHEBI:53233 | denotes | -yl |
| T1421 | 35957-35960 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1422 | 35961-35966 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1423 | 35967-35970 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1424 | 35970-35977 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1425 | 35977-36003 | CHEBI:86228;CHEBI:86228 | denotes | -2-nitrobenzenesulfonamide |
| T1426 | 36092-36104 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1427 | 36764-36767 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1428 | 37108-37123 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T1429 | 37124-37125 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T1430 | 37126-37129 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T1431 | 37129-37135 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1432 | 37166-37176 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1433 | 37178-37180 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T1434 | 37180-37187 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1435 | 37188-37189 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T1436 | 37191-37204 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1437 | 37205-37211 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1438 | 37211-37212 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1439 | 37212-37213 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1440 | 37213-37216 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T1441 | 37217-37220 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1442 | 37230-37237 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T1443 | 37237-37240 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1444 | 37240-37252 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1445 | 37252-37255 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1446 | 37255-37266 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1447 | 37355-37367 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1448 | 38027-38030 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1449 | 38373-38388 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T1450 | 38389-38390 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T1451 | 38391-38394 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T1452 | 38394-38400 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1453 | 38431-38441 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1454 | 38443-38445 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T1455 | 38445-38452 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1456 | 38453-38454 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T1457 | 38456-38469 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1458 | 38470-38476 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1459 | 38476-38477 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1460 | 38477-38478 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1461 | 38478-38481 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T1462 | 38482-38485 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1463 | 38495-38500 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T1464 | 38500-38503 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T1465 | 38503-38527 | CHEBI:36810;CHEBI:36810 | denotes | (trifluoromethyl)benzene |
| T1466 | 38527-38528 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T1467 | 38528-38530 | CHEBI:86228;CHEBI:86228 | denotes | 1- |
| T1468 | 38530-38541 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1469 | 38627-38639 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1470 | 39330-39333 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1471 | 39771-39786 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T1472 | 39787-39788 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T1473 | 39789-39792 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T1474 | 39792-39798 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1475 | 39829-39839 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1476 | 39841-39843 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T1477 | 39843-39850 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1478 | 39851-39852 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T1479 | 39854-39867 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1480 | 39868-39874 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1481 | 39874-39875 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1482 | 39875-39876 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1483 | 39876-39879 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T1484 | 39879-39880 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T1485 | 39880-39883 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1486 | 39893-39899 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T1487 | 39899-39902 | CHEBI:86228;CHEBI:86228 | denotes | -3- |
| T1488 | 39902-39914 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T1489 | 39914-39917 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T1490 | 39917-39928 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1491 | 40017-40029 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1492 | 40715-40718 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1493 | 41057-41076 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T1494 | 41077-41079 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1495 | 41084-41087 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T1496 | 41088-41089 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1497 | 41093-41094 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T1498 | 41094-41096 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T1499 | 41096-41109 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T1500 | 41166-41167 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1501 | 41167-41185 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1502 | 41186-41189 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1503 | 41190-41194 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T1504 | 41195-41201 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T1505 | 41201-41219 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T1506 | 41219-41220 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1507 | 41220-41223 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1508 | 41224-41230 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1509 | 41231-41243 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T1510 | 41243-41246 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1511 | 41254-41256 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T1512 | 41256-41269 | CHEBI:23132;CHEBI:23132 | denotes | chlorobenzene |
| T1513 | 41269-41272 | CHEBI:28714;CHEBI:28714 | denotes | -1- |
| T1514 | 41272-41283 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1515 | 41294-41302 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1516 | 41406-41407 | CHEBI:75508;CHEBI:75508 | denotes | 4 |
| T1517 | 41407-41429 | CHEBI:86228;CHEBI:86228 | denotes | -chlorobenzenesulfonyl |
| T1518 | 41430-41438 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T1519 | 41502-41509 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T1520 | 41563-41571 | CHEBI:46787;CHEBI:46787 | denotes | Solvents |
| T1521 | 41669-41676 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1522 | 41677-41683 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T1523 | 41697-41704 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1524 | 41823-41829 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T1525 | 41918-41924 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T1526 | 41951-41955 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1527 | 42022-42026 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1528 | 42053-42058 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1529 | 42609-42612 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1530 | 42994-42996 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T1531 | 42997-43007 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1532 | 43008-43032 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T1533 | 43033-43035 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1534 | 43051-43062 | CHEBI:86228;CHEBI:86228 | denotes | 3]dioxol-4- |
| T1535 | 43062-43065 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T1536 | 43065-43071 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1537 | 43074-43076 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T1538 | 43076-43082 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T1539 | 43082-43097 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrophenyl) |
| T1540 | 43097-43103 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1541 | 43103-43104 | CHEBI:86228;CHEBI:86228 | denotes | ] |
| T1542 | 43104-43109 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1543 | 43110-43116 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T1544 | 43118-43119 | CHEBI:86228;CHEBI:86228 | denotes | 4 |
| T1545 | 43126-43127 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1546 | 43127-43145 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1547 | 43145-43146 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1548 | 43146-43149 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1549 | 43150-43161 | CHEBI:53233;CHEBI:53233 | denotes | -5-{[(tert- |
| T1550 | 43161-43179 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T1551 | 43179-43180 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1552 | 43180-43183 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1553 | 43184-43190 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T1554 | 43191-43203 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-2-yl] |
| T1555 | 43204-43206 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T1556 | 43207-43212 | CHEBI:17939;CHEBI:17939 | denotes | purin |
| T1557 | 43212-43215 | CHEBI:17369;CHEBI:17369 | denotes | -6- |
| T1558 | 43215-43220 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T1559 | 43231-43239 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1560 | 43313-43321 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1561 | 43325-43327 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T1562 | 43327-43333 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T1563 | 43333-43354 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrobenazaldehyde |
| T1564 | 43413-43424 | CHEBI:15366;CHEBI:15366 | denotes | acetic acid |
| T1565 | 43502-43508 | CHEBI:35607;CHEBI:35607 | denotes | sodium |
| T1566 | 43509-43530 | CHEBI:28621;CHEBI:28621 | denotes | triacetoxyborohydride |
| T1567 | 43608-43616 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1568 | 43672-43679 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1569 | 43680-43686 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T1570 | 43692-43699 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1571 | 43818-43824 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T1572 | 43913-43919 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T1573 | 43946-43950 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1574 | 44011-44015 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1575 | 44044-44049 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1576 | 44624-44627 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1577 | 45034-45036 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T1578 | 45037-45047 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1579 | 45048-45072 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T1580 | 45073-45075 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T1581 | 45091-45105 | CHEBI:53233;CHEBI:53233 | denotes | 3]dioxol-4-yl] |
| T1582 | 45105-45111 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1583 | 45114-45129 | CHEBI:53233;CHEBI:53233 | denotes | 4-chlorophenyl) |
| T1584 | 45129-45135 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1585 | 45135-45136 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T1586 | 45136-45141 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1587 | 45142-45148 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T1588 | 45149-45152 | CHEBI:53233;CHEBI:53233 | denotes | -4- |
| T1589 | 45158-45159 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T1590 | 45178-45181 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1591 | 45182-45187 | CHEBI:82321;CHEBI:82321 | denotes | -5-{[ |
| T1592 | 45187-45188 | CHEBI:53233;CHEBI:53233 | denotes | ( |
| T1593 | 45192-45211 | CHEBI:82321;CHEBI:82321 | denotes | -butyldimethylsilyl |
| T1594 | 45211-45212 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1595 | 45212-45215 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1596 | 45216-45222 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1597 | 45223-45229 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1598 | 45229-45230 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1599 | 45230-45231 | CHEBI:82321;CHEBI:82321 | denotes | 2 |
| T1600 | 45231-45232 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1601 | 45232-45234 | CHEBI:82321;CHEBI:82321 | denotes | yl |
| T1602 | 45236-45238 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T1603 | 45247-45252 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T1604 | 45263-45271 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1605 | 45343-45361 | CHEBI:28105;CHEBI:28105 | denotes | chlorobenzaldehyde |
| T1606 | 45418-45429 | CHEBI:15366;CHEBI:15366 | denotes | acetic acid |
| T1607 | 45507-45513 | CHEBI:35607;CHEBI:35607 | denotes | sodium |
| T1608 | 45514-45535 | CHEBI:28621;CHEBI:28621 | denotes | triacetoxyborohydride |
| T1609 | 45613-45621 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1610 | 45677-45684 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1611 | 45685-45691 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T1612 | 45697-45704 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1613 | 45823-45829 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T1614 | 45918-45924 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T1615 | 45951-45955 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1616 | 46027-46031 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T1617 | 46063-46068 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T1618 | 46580-46583 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1619 | 46980-46995 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T1620 | 46996-46997 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T1621 | 46998-47001 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T1622 | 47001-47007 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1623 | 47038-47048 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1624 | 47050-47052 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T1625 | 47052-47059 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1626 | 47060-47061 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T1627 | 47063-47076 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1628 | 47077-47083 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1629 | 47083-47084 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1630 | 47084-47085 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1631 | 47085-47088 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T1632 | 47088-47089 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T1633 | 47089-47092 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T1634 | 47102-47115 | CHEBI:23132;CHEBI:23132 | denotes | chlorobenzene |
| T1635 | 47115-47116 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T1636 | 47116-47118 | CHEBI:28714;CHEBI:28714 | denotes | 1- |
| T1637 | 47118-47129 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T1638 | 47218-47230 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1639 | 47900-47903 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1640 | 48240-48241 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T1641 | 48246-48249 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T1642 | 48250-48260 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1643 | 48262-48264 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T1644 | 48264-48271 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1645 | 48275-48288 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1646 | 48289-48295 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1647 | 48295-48296 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T1648 | 48296-48297 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T1649 | 48297-48300 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T1650 | 48300-48301 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T1651 | 48301-48304 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1652 | 48305-48310 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1653 | 48313-48315 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T1654 | 48315-48321 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T1655 | 48321-48335 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrophenyl |
| T1656 | 48336-48342 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1657 | 48343-48348 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1658 | 48349-48355 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1659 | 48356-48363 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T1660 | 48364-48366 | CHEBI:52029;CHEBI:52029 | denotes | 3, |
| T1661 | 48366-48368 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T1662 | 48368-48372 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T1663 | 48461-48473 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1664 | 49214-49217 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1665 | 49571-49572 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T1666 | 49577-49580 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T1667 | 49581-49591 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T1668 | 49593-49595 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T1669 | 49595-49602 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T1670 | 49606-49619 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T1671 | 49620-49626 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T1672 | 49627-49631 | CHEBI:53233;CHEBI:53233 | denotes | 3-yl |
| T1673 | 49632-49635 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T1674 | 49636-49641 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T1675 | 49644-49646 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T1676 | 49659-49665 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1677 | 49666-49671 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T1678 | 49672-49678 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T1679 | 49679-49686 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T1680 | 49691-49695 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T1681 | 49784-49796 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T1682 | 50520-50523 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T1683 | 50809-50819 | GO:0010467 | denotes | Expression |
| T1684 | 50861-50869 | SP_10 | denotes | SARS-CoV |
| T1685 | 50870-50875 | PR:000000125 | denotes | nsp14 |
| T1686 | 50880-50885 | SP_6;NCBITaxon:9606 | denotes | human |
| T1687 | 51007-51015 | SO:0000155 | denotes | plasmids |
| T1688 | 51035-51044 | GO:0010467 | denotes | expressed |
| T1689 | 51048-51055 | NCBITaxon:562 | denotes | E. coli |
| T1690 | 51119-51127 | NCBITaxon:7742 | denotes | Vaccinia |
| T1691 | 51128-51133 | NCBITaxon:10239 | denotes | virus |
| T1692 | 51157-51164 | GO:0032991 | denotes | complex |
| T1693 | 51325-51327 | CHEBI:29238;CHEBI:29238 | denotes | 3H |
| T1694 | 51488-51495 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T1695 | 51503-51507 | CHEBI:9754;CHEBI:9754 | denotes | Tris |
| T1696 | 51508-51511 | CHEBI:17883;CHEBI:17883 | denotes | HCl |
| T1697 | 51527-51530 | CHEBI:18320;CHEBI:18320 | denotes | DTT |
| T1698 | 51537-51542 | CHEBI:6636;CHEBI:6636 | denotes | MgCl2 |
| T1699 | 51564-51566 | CHEBI:29238;CHEBI:29238 | denotes | 3H |
| T1700 | 51638-51646 | SP_10 | denotes | SARS-CoV |
| T1701 | 51647-51652 | PR:000000125 | denotes | nsp14 |
| T1702 | 51662-51670 | NCBITaxon:7742 | denotes | vaccinia |
| T1703 | 51671-51676 | NCBITaxon:10239 | denotes | virus |
| T1704 | 51712-51717 | SP_6;NCBITaxon:9606 | denotes | human |
| T1705 | 51732-51737 | PR:O43148 | denotes | hRNMT |
| T1706 | 51782-51791 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T1707 | 51810-51814 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T1708 | 51825-51829 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T1709 | 51960-51964 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T1710 | 51976-51984 | CHEBI:60004;CHEBI:60004 | denotes | mixtures |
| T1711 | 52049-52054 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T1712 | 52084-52101 | CHEBI:35702;CHEBI:35702 | denotes | diethylaminoethyl |
| T1713 | 52236-52252 | CHEBI:63050;CHEBI:63050 | denotes | ammonium formate |
| T1714 | 52272-52277 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T1715 | 52292-52299 | CHEBI:16236;CHEBI:16236 | denotes | ethanol |
| T1716 | 52362-52364 | CHEBI:29238;CHEBI:29238 | denotes | 3H |
| T1717 | 52680-52688 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T1718 | 53019-53026 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T1719 | 53054-53059 | CHEBI:46756;CHEBI:46756 | denotes | HEPES |
| T1720 | 53077-53081 | CHEBI:26710;CHEBI:26710 | denotes | NaCl |
| T1721 | 53086-53098 | CHEBI:51461;CHEBI:51461 | denotes | SYPRO orange |
| T1722 | 53099-53102 | CHEBI:37958;CHEBI:37958 | denotes | dye |
| T1723 | 53122-53130 | SP_10 | denotes | SARS-CoV |
| T1724 | 53131-53136 | PR:000000125 | denotes | nsp14 |
| T1725 | 53154-53162 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T1726 | 53192-53196 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T1727 | 53200-53205 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T1728 | 53261-53269 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T1729 | 53297-53300 | CHEBI:37958;CHEBI:37958 | denotes | dye |
| T1730 | 53547-53551 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T1731 | 53624-53631 | GO:0032508 | denotes | melting |
| T1732 | 54115-54123 | SP_10 | denotes | SARS-CoV |
| T1733 | 54223-54227 | CHEBI:24870;CHEBI:24870 | denotes | ions |
| T1734 | 54250-54258 | SP_10 | denotes | SARS-CoV |
| T1735 | 54259-54264 | PR:000000125 | denotes | nsp14 |
| T1736 | 54767-54775 | SP_10 | denotes | SARS-CoV |
| T1737 | 54776-54781 | PR:000000125 | denotes | nsp14 |
| T1738 | 54814-54822 | SP_10 | denotes | SARS-CoV |
| T1739 | 54823-54828 | PR:000000125 | denotes | nsp14 |
| T42 | 51153-51178 | NCBITaxon:10239 | denotes | D12 complex) and mRNA Cap |
| T92593 | 54250-54258 | SP_10 | denotes | SARS-CoV |
| T15931 | 54259-54264 | PR:000000125 | denotes | nsp14 |
| T86649 | 75-83 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T43192 | 88-96 | CHEBI:33893;CHEBI:33893 | denotes | reagents |
| T3261 | 206-213 | CHEBI:29320;CHEBI:29320 | denotes | calcium |
| T10589 | 214-221 | CHEBI:29239;CHEBI:29239 | denotes | hydride |
| T99839 | 284-290 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T52140 | 952-959 | CHEBI:46787;CHEBI:46787 | denotes | solvent |
| T30031 | 1021-1026 | CHEBI:1418;CHEBI:1418 | denotes | CH3CN |
| T39091 | 1130-1139 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T2577 | 1257-1266 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T24815 | 1290-1298 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T614 | 1302-1305 | CHEBI:51231;CHEBI:51231 | denotes | 5′- |
| T19968 | 1305-1310 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T95384 | 1310-1311 | CHEBI:75508;CHEBI:75508 | denotes | - |
| T33892 | 1311-1315 | CHEBI:51231;CHEBI:51231 | denotes | 2′,3 |
| T55720 | 1315-1331 | CHEBI:53250;CHEBI:53250 | denotes | ′-isopropylidene |
| T41124 | 1332-1341 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T59013 | 1420-1439 | CHEBI:53325;CHEBI:53325 | denotes | nitrobenzenesufonyl |
| T59951 | 1440-1448 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T13359 | 1481-1488 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T72737 | 1584-1591 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T51572 | 1692-1698 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T4728 | 1795-1803 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T86118 | 1874-1906 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T62627 | 1910-1911 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T73292 | 1911-1913 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T56519 | 1913-1926 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T95710 | 1926-1932 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T45397 | 1934-1936 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T96670 | 1936-1948 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T69786 | 1948-1951 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T24453 | 1951-1962 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T31575 | 1992-1993 | CHEBI:75508;CHEBI:75508 | denotes | 5 |
| T96563 | 1993-1994 | CHEBI:82321;CHEBI:82321 | denotes | ′ |
| T43267 | 1994-1995 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T88305 | 1995-2000 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T5438 | 2000-2002 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T60092 | 2002-2021 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T29954 | 2022-2031 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T50196 | 2065-2086 | CHEBI:86228;CHEBI:86228 | denotes | 4-nitrobenzenesufonyl |
| T14448 | 2087-2095 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T79305 | 2159-2163 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T69919 | 2487-2490 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T36490 | 2748-2757 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T37409 | 2773-2781 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T24357 | 2883-2888 | CHEBI:32031;CHEBI:32031 | denotes | K2CO3 |
| T81075 | 2984-2989 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T2114 | 2995-3002 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T5492 | 3103-3109 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T5574 | 3198-3204 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T59785 | 3231-3235 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T61924 | 3264-3272 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T68367 | 3341-3360 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T40445 | 3361-3363 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T4224 | 3368-3371 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T91423 | 3372-3373 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T12675 | 3377-3378 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T79796 | 3378-3380 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T73827 | 3380-3393 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T62607 | 3450-3451 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T53578 | 3451-3469 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T64666 | 3470-3473 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T28006 | 3474-3478 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T25194 | 3479-3485 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T51661 | 3485-3503 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T35859 | 3503-3504 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T59756 | 3504-3507 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T74145 | 3508-3514 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T18351 | 3515-3527 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T71610 | 3527-3530 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T27362 | 3537-3540 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T98530 | 3540-3552 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T56202 | 3552-3555 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T15954 | 3555-3566 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T27636 | 3699-3703 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T70470 | 3727-3732 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T31867 | 4231-4234 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T37264 | 4622-4624 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T61516 | 4625-4635 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T43297 | 4636-4660 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T26849 | 4661-4663 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T6291 | 4679-4681 | CHEBI:53233;CHEBI:53233 | denotes | 3] |
| T10899 | 4681-4687 | CHEBI:82321;CHEBI:82321 | denotes | dioxol |
| T30917 | 4687-4693 | CHEBI:53233;CHEBI:53233 | denotes | -4-yl] |
| T29054 | 4693-4699 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T91631 | 4699-4700 | CHEBI:53233;CHEBI:53233 | denotes | } |
| T71293 | 4700-4705 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T48278 | 4706-4712 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T81026 | 4714-4742 | CHEBI:53233;CHEBI:53233 | denotes | 4-[(tert-butyldimethylsilyl) |
| T93948 | 4742-4745 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T43751 | 4747-4748 | CHEBI:53233;CHEBI:53233 | denotes | 5 |
| T98761 | 4756-4757 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T36094 | 4757-4775 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T18228 | 4776-4779 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T76224 | 4780-4786 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T41246 | 4787-4793 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T37085 | 4793-4794 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T61179 | 4794-4799 | CHEBI:53233;CHEBI:53233 | denotes | 2-yl] |
| T12065 | 4800-4802 | CHEBI:53233;CHEBI:53233 | denotes | 9H |
| T53177 | 4802-4808 | CHEBI:35589;CHEBI:35589 | denotes | -purin |
| T82206 | 4809-4810 | CHEBI:53233;CHEBI:53233 | denotes | 6 |
| T57054 | 4811-4816 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T10400 | 4827-4835 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T2918 | 4906-4911 | CHEBI:32031;CHEBI:32031 | denotes | K2CO3 |
| T54095 | 4944-4954 | CHEBI:48498;CHEBI:48498 | denotes | thiophenol |
| T6657 | 5053-5060 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T33281 | 5110-5117 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T65041 | 5118-5122 | CHEBI:32145;CHEBI:32145 | denotes | NaOH |
| T40366 | 5123-5131 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T1989 | 5145-5152 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T99804 | 5263-5269 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T52387 | 5358-5364 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T84377 | 5392-5396 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T32932 | 5476-5480 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T16692 | 5504-5509 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T39500 | 5943-5946 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T98523 | 6297-6306 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T86450 | 6398-6403 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T52872 | 6488-6492 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T28770 | 6495-6503 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T10210 | 6571-6574 | CHEBI:62946;CHEBI:62946 | denotes | NH3 |
| T88591 | 6578-6582 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T84694 | 6660-6666 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T97793 | 6721-6733 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T99254 | 6797-6805 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T33833 | 6853-6858 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T70218 | 6859-6866 | CHEBI:46923;CHEBI:46923 | denotes | dioxane |
| T61315 | 6883-6891 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T6422 | 6968-6969 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T47786 | 6974-6977 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T39924 | 6978-6988 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T95618 | 6990-6992 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T15935 | 6992-6999 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T58434 | 7003-7016 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T23506 | 7017-7023 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T76962 | 7023-7028 | CHEBI:15533;CHEBI:15533 | denotes | -3-yl |
| T91563 | 7028-7029 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T49922 | 7029-7032 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T43108 | 7033-7038 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T94441 | 7039-7044 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T7732 | 7045-7051 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T70644 | 7052-7059 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T67322 | 7059-7060 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T44034 | 7060-7064 | CHEBI:82321;CHEBI:82321 | denotes | 3,4- |
| T18776 | 7064-7068 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T80338 | 7160-7172 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T77870 | 7704-7707 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T28859 | 8009-8010 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T41785 | 8010-8014 | CHEBI:52029;CHEBI:52029 | denotes | 2,2- |
| T97314 | 8014-8023 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl- |
| T32713 | 8023-8033 | CHEBI:52029;CHEBI:52029 | denotes | tetrahydro |
| T98800 | 8033-8036 | CHEBI:53233;CHEBI:53233 | denotes | -2H |
| T70619 | 8050-8053 | CHEBI:52029;CHEBI:52029 | denotes | 1,3 |
| T56184 | 8053-8054 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T16818 | 8054-8060 | CHEBI:52029;CHEBI:52029 | denotes | dioxol |
| T71070 | 8060-8065 | CHEBI:53233;CHEBI:53233 | denotes | -4-yl |
| T17264 | 8112-8121 | CHEBI:53233;CHEBI:53233 | denotes | 4-[(tert- |
| T92170 | 8121-8139 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T11160 | 8139-8140 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T1841 | 8140-8143 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T29745 | 8143-8155 | CHEBI:53233;CHEBI:53233 | denotes | ]-5-{[(tert- |
| T95154 | 8155-8173 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T61817 | 8173-8174 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T88971 | 8174-8177 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T34714 | 8177-8178 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T89053 | 8178-8184 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T20420 | 8184-8185 | CHEBI:53233;CHEBI:53233 | denotes | } |
| T79823 | 8185-8191 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T49653 | 8191-8196 | CHEBI:53233;CHEBI:53233 | denotes | -3-yl |
| T84503 | 8197-8200 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T87203 | 8201-8206 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T18939 | 8207-8212 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T75533 | 8227-8233 | CHEBI:75508;CHEBI:75508 | denotes | butoxy |
| T37718 | 8234-8242 | CHEBI:23019;CHEBI:23019 | denotes | carbonyl |
| T50416 | 8243-8248 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T88272 | 8249-8258 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T18742 | 8269-8277 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T4622 | 8347-8355 | CHEBI:17478;CHEBI:17478 | denotes | aldehyde |
| T82195 | 8416-8427 | CHEBI:15366;CHEBI:15366 | denotes | acetic acid |
| T9375 | 8516-8522 | CHEBI:35607;CHEBI:35607 | denotes | sodium |
| T8158 | 8523-8544 | CHEBI:28621;CHEBI:28621 | denotes | triacetoxyborohydride |
| T27845 | 8622-8629 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T73639 | 8685-8692 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T71101 | 8693-8699 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T96786 | 8713-8720 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T30010 | 8831-8837 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T67189 | 8926-8932 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T22030 | 8959-8963 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T49057 | 9024-9028 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T81566 | 9057-9062 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T29671 | 9588-9591 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T77495 | 10008-10027 | CHEBI:53233;CHEBI:53233 | denotes | 3,4-dihydroxyoxolan |
| T7135 | 10030-10032 | CHEBI:53233;CHEBI:53233 | denotes | yl |
| T35703 | 10064-10066 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T50990 | 10067-10077 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T26796 | 10079-10081 | CHEBI:17500;CHEBI:17500 | denotes | 4- |
| T4175 | 10081-10088 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T65952 | 10089-10090 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T10649 | 10090-10092 | CHEBI:17500;CHEBI:17500 | denotes | -( |
| T3672 | 10092-10105 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T60171 | 10106-10112 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T38256 | 10112-10113 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T3560 | 10113-10114 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T94233 | 10114-10117 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T42442 | 10118-10121 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T43064 | 10122-10127 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T8061 | 10135-10155 | CHEBI:86228;CHEBI:86228 | denotes | 2-azaniumylbutanoate |
| T17648 | 10169-10171 | CHEBI:53424;CHEBI:53424 | denotes | 22 |
| T7216 | 10253-10258 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T10240 | 10293-10301 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T70971 | 10358-10363 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T82680 | 10381-10388 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T99687 | 10389-10393 | CHEBI:48607;CHEBI:48607 | denotes | LiOH |
| T12422 | 10394-10402 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T45037 | 10500-10507 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T26603 | 10508-10511 | CHEBI:17883;CHEBI:17883 | denotes | HCl |
| T15792 | 10512-10520 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T22239 | 10526-10533 | CHEBI:46787;CHEBI:46787 | denotes | solvent |
| T42331 | 10639-10645 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T43871 | 10706-10718 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T83104 | 10782-10790 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T77066 | 10838-10843 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T3324 | 11375-11378 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T32226 | 11699-11704 | CHEBI:30756;CHEBI:30756 | denotes | -9-yl |
| T22539 | 11705-11731 | CHEBI:53233;CHEBI:53233 | denotes | -3,4-dihydroxyoxolan-2-yl] |
| T43743 | 11731-11737 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T65681 | 11754-11775 | CHEBI:30756;CHEBI:30756 | denotes | 6-amino-9H-purin-9-yl |
| T74576 | 11777-11779 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T56336 | 11779-11786 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T63032 | 11786-11787 | CHEBI:17500;CHEBI:17500 | denotes | - |
| T71636 | 11787-11789 | CHEBI:34018;CHEBI:34018 | denotes | 5- |
| T12303 | 11789-11790 | CHEBI:17500;CHEBI:17500 | denotes | ( |
| T91451 | 11790-11803 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T56103 | 11804-11810 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T94307 | 11811-11812 | CHEBI:17500;CHEBI:17500 | denotes | 3 |
| T57389 | 11816-11819 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T45750 | 11820-11825 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T71688 | 11826-11831 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T33280 | 11832-11841 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T22610 | 11933-11945 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T96226 | 12629-12632 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T86741 | 12948-12952 | CHEBI:30756;CHEBI:30756 | denotes | 9-yl |
| T58744 | 12954-12978 | CHEBI:53233;CHEBI:53233 | denotes | 3,4-dihydroxyoxolan-2-yl |
| T47857 | 12979-12985 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T38462 | 13002-13023 | CHEBI:30756;CHEBI:30756 | denotes | 6-amino-9H-purin-9-yl |
| T83257 | 13025-13027 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T64218 | 13027-13034 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T51011 | 13034-13035 | CHEBI:82321;CHEBI:82321 | denotes | - |
| T77268 | 13035-13036 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T44485 | 13036-13037 | CHEBI:82321;CHEBI:82321 | denotes | - |
| T32686 | 13037-13038 | CHEBI:17500;CHEBI:17500 | denotes | ( |
| T55257 | 13038-13051 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T66651 | 13052-13058 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T12230 | 13058-13059 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T95331 | 13059-13063 | CHEBI:82321;CHEBI:82321 | denotes | 3-yl |
| T2115 | 13064-13067 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T86076 | 13068-13073 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T70057 | 13080-13090 | CHEBI:22965;CHEBI:22965 | denotes | butanamide |
| T84042 | 13104-13106 | CHEBI:53424;CHEBI:53424 | denotes | 22 |
| T67269 | 13190-13195 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T97010 | 13250-13258 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T83843 | 13309-13312 | CHEBI:62946;CHEBI:62946 | denotes | NH3 |
| T7244 | 13316-13320 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T36733 | 13364-13372 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T77353 | 13466-13472 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T73055 | 13533-13545 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T11993 | 13609-13617 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T35043 | 13665-13670 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T3608 | 14230-14233 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T38632 | 14540-14549 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T27381 | 14569-14577 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T70032 | 14644-14651 | CHEBI:15858;CHEBI:15858 | denotes | bromide |
| T50931 | 14652-14659 | CHEBI:33893;CHEBI:33893 | denotes | reagent |
| T24500 | 14754-14761 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T75121 | 14800-14807 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T6076 | 14908-14914 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T31885 | 15003-15009 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T20744 | 15036-15040 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T50504 | 15069-15077 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T32363 | 15147-15149 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T13211 | 15150-15160 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T96959 | 15161-15185 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T81968 | 15186-15188 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T62563 | 15204-15212 | CHEBI:53233;CHEBI:53233 | denotes | 3]dioxol |
| T71718 | 15213-15214 | CHEBI:53233;CHEBI:53233 | denotes | 4 |
| T20039 | 15214-15217 | CHEBI:28714;CHEBI:28714 | denotes | -yl |
| T58470 | 15218-15224 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T88741 | 15226-15231 | CHEBI:34594;CHEBI:34594 | denotes | butyl |
| T90855 | 15232-15237 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T4988 | 15238-15244 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T98861 | 15246-15247 | CHEBI:53233;CHEBI:53233 | denotes | 4 |
| T30207 | 15255-15273 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T63301 | 15274-15277 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T91694 | 15308-15311 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T32425 | 15312-15318 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T53106 | 15319-15325 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T98099 | 15325-15326 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T44173 | 15326-15331 | CHEBI:53233;CHEBI:53233 | denotes | 2-yl] |
| T15637 | 15332-15334 | CHEBI:53233;CHEBI:53233 | denotes | 9H |
| T88656 | 15335-15340 | CHEBI:35589;CHEBI:35589 | denotes | purin |
| T83607 | 15343-15348 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T96207 | 15411-15424 | CHEBI:20067;CHEBI:20067 | denotes | 1-bromobutane |
| T31939 | 15482-15486 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T15973 | 15515-15520 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T79430 | 16115-16118 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T77832 | 16499-16501 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T96984 | 16502-16512 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T12300 | 16513-16537 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T64622 | 16538-16540 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T81649 | 16556-16570 | CHEBI:53233;CHEBI:53233 | denotes | 3]dioxol-4-yl] |
| T60058 | 16570-16576 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T67441 | 16578-16579 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T59101 | 16579-16593 | CHEBI:8502;CHEBI:8502 | denotes | -phenylpropyl) |
| T10803 | 16593-16598 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T99412 | 16599-16605 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T27421 | 16606-16609 | CHEBI:53233;CHEBI:53233 | denotes | -4- |
| T45002 | 16635-16638 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T25885 | 16640-16645 | CHEBI:53233;CHEBI:53233 | denotes | 5-{[( |
| T76580 | 16649-16650 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T82459 | 16650-16668 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T94186 | 16668-16669 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T75385 | 16669-16672 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T89594 | 16673-16679 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T24507 | 16680-16686 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T59105 | 16686-16689 | CHEBI:53233;CHEBI:53233 | denotes | -2- |
| T72096 | 16689-16691 | CHEBI:82321;CHEBI:82321 | denotes | yl |
| T34424 | 16691-16693 | CHEBI:53233;CHEBI:53233 | denotes | ]- |
| T54801 | 16693-16695 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T56070 | 16695-16701 | CHEBI:35589;CHEBI:35589 | denotes | -purin |
| T43386 | 16704-16709 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T11041 | 16775-16776 | CHEBI:17824;CHEBI:17824 | denotes | 1 |
| T17301 | 16776-16777 | CHEBI:8502;CHEBI:8502 | denotes | - |
| T35667 | 16777-16782 | CHEBI:47265;CHEBI:47265 | denotes | bromo |
| T19186 | 16782-16798 | CHEBI:17824;CHEBI:17824 | denotes | -3-phenylpropane |
| T54530 | 16856-16860 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T27602 | 16888-16893 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T43770 | 17475-17478 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T80130 | 17493-17498 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T75110 | 17891-17923 | CHEBI:53233;CHEBI:53233 | denotes | 2-dimethyl-tetrahydro-2H-furo[3, |
| T17943 | 17924-17925 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T24037 | 17929-17930 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T86603 | 17930-17932 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T59348 | 17932-17933 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T37288 | 17933-17939 | CHEBI:52029;CHEBI:52029 | denotes | dioxol |
| T39000 | 17939-17945 | CHEBI:53233;CHEBI:53233 | denotes | -4-yl] |
| T31856 | 17945-17951 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T47118 | 17995-18000 | CHEBI:53233;CHEBI:53233 | denotes | tert- |
| T15383 | 18000-18018 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T47564 | 18018-18019 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T29123 | 18019-18022 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T88497 | 18022-18027 | CHEBI:53233;CHEBI:53233 | denotes | ]-5-{ |
| T48709 | 18028-18034 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T67159 | 18034-18052 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T41322 | 18052-18053 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T77050 | 18053-18056 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T15677 | 18057-18063 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T31769 | 18064-18070 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T33192 | 18070-18076 | CHEBI:53233;CHEBI:53233 | denotes | -3-yl] |
| T11035 | 18076-18079 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T21898 | 18080-18085 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T71397 | 18092-18101 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T12961 | 18248-18252 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T70489 | 18281-18286 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T84309 | 18879-18882 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T58714 | 19287-19288 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T60342 | 19293-19296 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T65612 | 19297-19307 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T42180 | 19309-19311 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T82658 | 19311-19318 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T41862 | 19322-19335 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T39392 | 19336-19342 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T89517 | 19342-19343 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T16740 | 19343-19344 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T19135 | 19344-19345 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T43742 | 19345-19348 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T82076 | 19348-19351 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T98620 | 19352-19357 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T17528 | 19359-19364 | CHEBI:34594;CHEBI:34594 | denotes | butyl |
| T68224 | 19365-19370 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T64086 | 19371-19377 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T30277 | 19378-19385 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T19025 | 19386-19390 | CHEBI:53233;CHEBI:53233 | denotes | 3,4- |
| T83414 | 19390-19394 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T86511 | 19484-19496 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T14604 | 19660-19664 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T9536 | 20189-20192 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T38868 | 20522-20523 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T91949 | 20528-20531 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T49295 | 20532-20542 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T28492 | 20544-20546 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T77208 | 20546-20553 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T39603 | 20557-20570 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T52817 | 20571-20577 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T91907 | 20577-20578 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T56213 | 20578-20583 | CHEBI:53233;CHEBI:53233 | denotes | 3-yl] |
| T76550 | 20583-20586 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T36483 | 20587-20592 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T68718 | 20594-20596 | CHEBI:17824;CHEBI:17824 | denotes | 3- |
| T77501 | 20596-20608 | CHEBI:8102;CHEBI:8102 | denotes | phenylpropyl |
| T56816 | 20609-20614 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T84634 | 20615-20621 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T51391 | 20622-20629 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T81555 | 20630-20634 | CHEBI:53233;CHEBI:53233 | denotes | 3,4- |
| T98146 | 20634-20638 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T33829 | 20729-20741 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T10815 | 21434-21437 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T83945 | 21760-21777 | CHEBI:53233;CHEBI:53233 | denotes | 4-dihydroxyoxolan |
| T7147 | 21778-21779 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T56766 | 21780-21782 | CHEBI:53233;CHEBI:53233 | denotes | yl |
| T96958 | 21783-21789 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T37005 | 21814-21816 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T20863 | 21817-21827 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T19679 | 21829-21831 | CHEBI:17500;CHEBI:17500 | denotes | 4- |
| T77075 | 21831-21838 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T41949 | 21838-21839 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T22088 | 21839-21840 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T85300 | 21840-21841 | CHEBI:17500;CHEBI:17500 | denotes | - |
| T16069 | 21841-21842 | CHEBI:62946;CHEBI:62946 | denotes | ( |
| T4614 | 21842-21855 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T39015 | 21856-21862 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T78649 | 21862-21868 | CHEBI:15533;CHEBI:15533 | denotes | -3-yl] |
| T51928 | 21868-21871 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T54744 | 21872-21877 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T59187 | 21878-21883 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T40939 | 21884-21893 | CHEBI:17968;CHEBI:17968 | denotes | butanoate |
| T8624 | 21985-21997 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T41103 | 22691-22694 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T67979 | 23019-23034 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T32544 | 23037-23039 | CHEBI:53233;CHEBI:53233 | denotes | yl |
| T12991 | 23040-23046 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T86322 | 23079-23083 | CHEBI:30756;CHEBI:30756 | denotes | 9-yl |
| T2693 | 23084-23086 | CHEBI:17500;CHEBI:17500 | denotes | -4 |
| T25161 | 23086-23087 | CHEBI:34018;CHEBI:34018 | denotes | - |
| T69413 | 23087-23094 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T26102 | 23094-23098 | CHEBI:17500;CHEBI:17500 | denotes | -5-( |
| T20939 | 23098-23111 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T70312 | 23112-23118 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T56764 | 23118-23124 | CHEBI:15533;CHEBI:15533 | denotes | -3-yl] |
| T75470 | 23124-23127 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T3995 | 23128-23133 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T67962 | 23134-23139 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T85476 | 23140-23153 | CHEBI:30772;CHEBI:30772 | denotes | butanoic acid |
| T88015 | 23234-23239 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T32144 | 23277-23285 | CHEBI:46787;CHEBI:46787 | denotes | solvents |
| T73518 | 23342-23347 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T36371 | 23365-23369 | CHEBI:48607;CHEBI:48607 | denotes | LiOH |
| T62284 | 23370-23377 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T5176 | 23378-23386 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T58294 | 23488-23491 | CHEBI:17883;CHEBI:17883 | denotes | HCl |
| T17055 | 23492-23499 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T68995 | 23500-23508 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T64029 | 23510-23518 | CHEBI:46787;CHEBI:46787 | denotes | Solvents |
| T62206 | 23625-23631 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T74306 | 23692-23704 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T36288 | 23768-23776 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T43085 | 23824-23829 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T91454 | 23834-23845 | CHEBI:47032;CHEBI:47032 | denotes | 1,4-dioxane |
| T2736 | 24353-24356 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T79216 | 24668-24683 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T85055 | 24684-24685 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T43977 | 24686-24689 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T33776 | 24689-24695 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T65828 | 24726-24736 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T82249 | 24738-24740 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T57163 | 24740-24747 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T86787 | 24748-24749 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T88206 | 24751-24764 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T75477 | 24765-24771 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T88093 | 24771-24772 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T95303 | 24772-24773 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T3186 | 24773-24776 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T92631 | 24776-24777 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T16525 | 24777-24780 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T41900 | 24790-24802 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T40897 | 24802-24805 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T93891 | 24805-24816 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T65427 | 24904-24916 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T35276 | 25513-25516 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T14444 | 25839-25871 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T86614 | 25875-25876 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T55502 | 25876-25878 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T27030 | 25878-25891 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T26242 | 25891-25897 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T17678 | 25899-25901 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T59084 | 25901-25908 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T86083 | 25908-25911 | CHEBI:86228;CHEBI:86228 | denotes | -2- |
| T44502 | 25911-25923 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T30124 | 25923-25926 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T12702 | 25926-25937 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T43724 | 25967-25969 | CHEBI:75508;CHEBI:75508 | denotes | 5′ |
| T15754 | 25969-25970 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T15605 | 25970-25975 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T66517 | 25975-25977 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T51285 | 25977-25996 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T60654 | 25997-26006 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T59959 | 26040-26042 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T71386 | 26042-26049 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T64311 | 26049-26071 | CHEBI:86228;CHEBI:86228 | denotes | -2-nitrobenzenesufonyl |
| T25560 | 26072-26080 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T12660 | 26144-26148 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T35215 | 26551-26554 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T40993 | 26837-26869 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T62855 | 26873-26874 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T18856 | 26874-26876 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T92405 | 26876-26889 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T62906 | 26899-26906 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T14229 | 26906-26909 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T73095 | 26909-26921 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T91256 | 26921-26924 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T81134 | 26924-26935 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T58600 | 26965-26967 | CHEBI:75508;CHEBI:75508 | denotes | 5′ |
| T12200 | 26967-26968 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T33578 | 26968-26973 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T50826 | 26973-26975 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T38141 | 26975-26994 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T17003 | 26995-27004 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T78529 | 27038-27040 | CHEBI:86228;CHEBI:86228 | denotes | 2- |
| T7741 | 27040-27047 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T22950 | 27047-27069 | CHEBI:86228;CHEBI:86228 | denotes | -4-nitrobenzenesufonyl |
| T16793 | 27070-27078 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T88265 | 27142-27146 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T82081 | 27516-27519 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T26652 | 27802-27834 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T26468 | 27838-27839 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T67874 | 27839-27841 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T80666 | 27841-27854 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T24491 | 27864-27869 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T43584 | 27869-27872 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T19738 | 27872-27896 | CHEBI:36810;CHEBI:36810 | denotes | (trifluoromethyl)benzene |
| T81878 | 27896-27897 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T11024 | 27897-27899 | CHEBI:86228;CHEBI:86228 | denotes | 1- |
| T4653 | 27899-27910 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T26922 | 27921-27929 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T37045 | 27933-27934 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T78171 | 27934-27935 | CHEBI:53250;CHEBI:53250 | denotes | ′ |
| T33253 | 27935-27936 | CHEBI:75508;CHEBI:75508 | denotes | - |
| T52510 | 27936-27941 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T10078 | 27941-27942 | CHEBI:75508;CHEBI:75508 | denotes | - |
| T92577 | 27942-27962 | CHEBI:53250;CHEBI:53250 | denotes | 2′,3′-isopropylidene |
| T98848 | 27963-27972 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T6780 | 28073-28075 | CHEBI:86228;CHEBI:86228 | denotes | 2- |
| T90464 | 28075-28080 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T13282 | 28080-28112 | CHEBI:86228;CHEBI:86228 | denotes | -4-trifluoromethylbenzenesufonyl |
| T47375 | 28113-28121 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T91473 | 28186-28193 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T29148 | 28240-28245 | CHEBI:2511;CHEBI:2511 | denotes | argon |
| T37167 | 28260-28267 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T88824 | 28303-28308 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T70018 | 28322-28329 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T75778 | 28450-28456 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T42939 | 28545-28551 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T97301 | 28578-28582 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T5962 | 28651-28655 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T51133 | 29043-29046 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T98719 | 29388-29420 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro-2H-furo[3,4- |
| T64923 | 29424-29425 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T19618 | 29425-29427 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T21752 | 29427-29440 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T69104 | 29440-29446 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T6973 | 29448-29450 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T6632 | 29450-29456 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T32297 | 29456-29459 | CHEBI:86228;CHEBI:86228 | denotes | -3- |
| T3937 | 29459-29471 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T22911 | 29471-29474 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T94422 | 29474-29485 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T41796 | 29515-29517 | CHEBI:75508;CHEBI:75508 | denotes | 5′ |
| T29317 | 29517-29518 | CHEBI:50217;CHEBI:50217 | denotes | - |
| T14374 | 29518-29523 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T34149 | 29523-29525 | CHEBI:50217;CHEBI:50217 | denotes | -2 |
| T75460 | 29525-29544 | CHEBI:53250;CHEBI:53250 | denotes | ′,3′-isopropylidene |
| T57966 | 29545-29554 | CHEBI:22260;CHEBI:22260 | denotes | adenosine |
| T37315 | 29588-29590 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T51836 | 29590-29596 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T55660 | 29596-29618 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrobenzenesufonyl |
| T3877 | 29619-29627 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T85531 | 29691-29695 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T63694 | 30074-30077 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T39424 | 30363-30382 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T79131 | 30383-30385 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T56876 | 30390-30393 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T1840 | 30394-30395 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T79993 | 30399-30400 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T59259 | 30400-30402 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T58344 | 30402-30415 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T56893 | 30472-30473 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T73747 | 30473-30491 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T18438 | 30492-30495 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T54841 | 30496-30500 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T97077 | 30501-30507 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T68234 | 30507-30525 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T94264 | 30525-30526 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T45887 | 30526-30529 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T38709 | 30530-30536 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T31272 | 30537-30549 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T72011 | 30549-30552 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T23440 | 30559-30562 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T27327 | 30562-30569 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T65448 | 30569-30572 | CHEBI:86228;CHEBI:86228 | denotes | -2- |
| T41958 | 30572-30584 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T14164 | 30584-30587 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T27301 | 30587-30598 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T19888 | 30729-30733 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T53371 | 30757-30762 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T67172 | 31322-31325 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T11579 | 31731-31750 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T57065 | 31751-31753 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T59700 | 31758-31761 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T59722 | 31762-31763 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T42544 | 31767-31768 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T89251 | 31768-31770 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T97990 | 31770-31783 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T80122 | 31840-31841 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T27927 | 31841-31859 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T35965 | 31860-31863 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T56636 | 31864-31868 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T31702 | 31869-31875 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T78929 | 31875-31893 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T25606 | 31893-31894 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T51248 | 31894-31897 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T25004 | 31898-31904 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T31765 | 31905-31917 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T85183 | 31917-31920 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T36168 | 31927-31930 | CHEBI:86228;CHEBI:86228 | denotes | -2- |
| T30288 | 31930-31937 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T52663 | 31937-31940 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T78115 | 31940-31952 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T41784 | 31952-31955 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T81810 | 31955-31966 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T89493 | 32097-32101 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T31016 | 32125-32130 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T97646 | 32606-32609 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T87470 | 33014-33033 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T54024 | 33034-33036 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T23527 | 33041-33044 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T99559 | 33045-33046 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T85766 | 33050-33051 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T61574 | 33051-33053 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T68998 | 33053-33066 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T87014 | 33123-33124 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T85986 | 33124-33142 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T75304 | 33143-33146 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T65071 | 33147-33151 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T97121 | 33152-33158 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T81982 | 33158-33176 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T83644 | 33176-33177 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T41506 | 33177-33180 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T90520 | 33181-33187 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T17006 | 33188-33200 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T97336 | 33200-33203 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T35230 | 33211-33213 | CHEBI:86228;CHEBI:86228 | denotes | 2- |
| T15021 | 33213-33218 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T62058 | 33218-33221 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T6656 | 33221-33245 | CHEBI:36810;CHEBI:36810 | denotes | (trifluoromethyl)benzene |
| T57151 | 33245-33246 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T62009 | 33246-33248 | CHEBI:86228;CHEBI:86228 | denotes | 1- |
| T50319 | 33248-33259 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T36780 | 33388-33392 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T97406 | 33416-33421 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T29610 | 34010-34013 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T79736 | 34500-34519 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T99248 | 34520-34522 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T39597 | 34527-34530 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T56665 | 34531-34532 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T35447 | 34536-34537 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T97750 | 34537-34539 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T83830 | 34539-34552 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T20304 | 34609-34610 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T62631 | 34610-34628 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T63884 | 34629-34632 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T90530 | 34633-34637 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T25418 | 34638-34644 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T68934 | 34644-34662 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T72167 | 34662-34663 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T99707 | 34663-34666 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T73688 | 34667-34673 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T12385 | 34674-34686 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T47592 | 34686-34689 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T88452 | 34696-34699 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T44537 | 34699-34705 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T9887 | 34705-34708 | CHEBI:86228;CHEBI:86228 | denotes | -3- |
| T2529 | 34708-34720 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T78752 | 34720-34723 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T86987 | 34723-34734 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T82290 | 34865-34869 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T48557 | 34893-34898 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T48829 | 35413-35416 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T68994 | 35820-35821 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T49736 | 35821-35822 | CHEBI:34018;CHEBI:34018 | denotes | , |
| T49263 | 35822-35824 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T19814 | 35824-35848 | CHEBI:47019;CHEBI:47019 | denotes | dihydroxytetrahydrofuran |
| T99082 | 35849-35853 | CHEBI:53233;CHEBI:53233 | denotes | 2-yl |
| T5309 | 35854-35860 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T89418 | 35883-35886 | CHEBI:34018;CHEBI:34018 | denotes | 2-( |
| T71642 | 35886-35907 | CHEBI:30756;CHEBI:30756 | denotes | 6-amino-9H-purin-9-yl |
| T75823 | 35908-35911 | CHEBI:34018;CHEBI:34018 | denotes | -4- |
| T15257 | 35911-35918 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T56352 | 35918-35922 | CHEBI:34018;CHEBI:34018 | denotes | -5-( |
| T66785 | 35922-35935 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T96828 | 35936-35951 | CHEBI:27902;CHEBI:27902 | denotes | tetrahydrofuran |
| T72083 | 35951-35952 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T20873 | 35952-35953 | CHEBI:34018;CHEBI:34018 | denotes | 3 |
| T76228 | 35953-35956 | CHEBI:53233;CHEBI:53233 | denotes | -yl |
| T81792 | 35957-35960 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T7400 | 35961-35966 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T5805 | 35967-35970 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T91433 | 35970-35977 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T94787 | 35977-36003 | CHEBI:86228;CHEBI:86228 | denotes | -2-nitrobenzenesulfonamide |
| T17422 | 36092-36104 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T16900 | 36764-36767 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T9646 | 37108-37123 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T9486 | 37124-37125 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T17557 | 37126-37129 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T47501 | 37129-37135 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T76951 | 37166-37176 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T96155 | 37178-37180 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T5259 | 37180-37187 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T85099 | 37188-37189 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T50359 | 37191-37204 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T76632 | 37205-37211 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T56362 | 37211-37212 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T67443 | 37212-37213 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T80801 | 37213-37216 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T80068 | 37217-37220 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T36872 | 37230-37237 | CHEBI:44520;CHEBI:44520 | denotes | methoxy |
| T86174 | 37237-37240 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T19833 | 37240-37252 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T31704 | 37252-37255 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T76634 | 37255-37266 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T76816 | 37355-37367 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T69796 | 38027-38030 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T9081 | 38373-38388 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T84269 | 38389-38390 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T69082 | 38391-38394 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T69733 | 38394-38400 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T41826 | 38431-38441 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T59624 | 38443-38445 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T23559 | 38445-38452 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T28637 | 38453-38454 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T71725 | 38456-38469 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T78504 | 38470-38476 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T39399 | 38476-38477 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T78395 | 38477-38478 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T72162 | 38478-38481 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T41623 | 38482-38485 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T99360 | 38495-38500 | CHEBI:29785;CHEBI:29785 | denotes | nitro |
| T1872 | 38500-38503 | CHEBI:86228;CHEBI:86228 | denotes | -4- |
| T89980 | 38503-38527 | CHEBI:36810;CHEBI:36810 | denotes | (trifluoromethyl)benzene |
| T78608 | 38527-38528 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T83142 | 38528-38530 | CHEBI:86228;CHEBI:86228 | denotes | 1- |
| T18825 | 38530-38541 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T96175 | 38627-38639 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T8921 | 39330-39333 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T40026 | 39771-39786 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T28765 | 39787-39788 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T9151 | 39789-39792 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T2628 | 39792-39798 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T10304 | 39829-39839 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T30594 | 39841-39843 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T33230 | 39843-39850 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T38807 | 39851-39852 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T78456 | 39854-39867 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T45407 | 39868-39874 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T96949 | 39874-39875 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T30771 | 39875-39876 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T52396 | 39876-39879 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T27861 | 39879-39880 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T30803 | 39880-39883 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T29803 | 39893-39899 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T18253 | 39899-39902 | CHEBI:86228;CHEBI:86228 | denotes | -3- |
| T10920 | 39902-39914 | CHEBI:27798;CHEBI:27798 | denotes | nitrobenzene |
| T29304 | 39914-39917 | CHEBI:86228;CHEBI:86228 | denotes | -1- |
| T57790 | 39917-39928 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T31150 | 40017-40029 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T95477 | 40715-40718 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T84702 | 41057-41076 | CHEBI:53233;CHEBI:53233 | denotes | dimethyl-tetrahydro |
| T58979 | 41077-41079 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T83384 | 41084-41087 | CHEBI:53233;CHEBI:53233 | denotes | [3, |
| T81396 | 41088-41089 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T35056 | 41093-41094 | CHEBI:53233;CHEBI:53233 | denotes | 1 |
| T57925 | 41094-41096 | CHEBI:52029;CHEBI:52029 | denotes | ,3 |
| T25773 | 41096-41109 | CHEBI:53233;CHEBI:53233 | denotes | ]dioxol-4-yl] |
| T78363 | 41166-41167 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T98012 | 41167-41185 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T78667 | 41186-41189 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T30177 | 41190-41194 | CHEBI:53233;CHEBI:53233 | denotes | -5-{ |
| T65451 | 41195-41201 | CHEBI:53233;CHEBI:53233 | denotes | (tert- |
| T67515 | 41201-41219 | CHEBI:8502;CHEBI:8502 | denotes | butyldimethylsilyl |
| T38465 | 41219-41220 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T95614 | 41220-41223 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T12953 | 41224-41230 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T31857 | 41231-41243 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-3-yl] |
| T23130 | 41243-41246 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T29433 | 41254-41256 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T48427 | 41256-41269 | CHEBI:23132;CHEBI:23132 | denotes | chlorobenzene |
| T20740 | 41269-41272 | CHEBI:28714;CHEBI:28714 | denotes | -1- |
| T83097 | 41272-41283 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T36071 | 41294-41302 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T61117 | 41406-41407 | CHEBI:75508;CHEBI:75508 | denotes | 4 |
| T43640 | 41407-41429 | CHEBI:86228;CHEBI:86228 | denotes | -chlorobenzenesulfonyl |
| T85525 | 41430-41438 | CHEBI:17996;CHEBI:17996 | denotes | chloride |
| T10406 | 41502-41509 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T86047 | 41563-41571 | CHEBI:46787;CHEBI:46787 | denotes | Solvents |
| T70835 | 41669-41676 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T37082 | 41677-41683 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T2244 | 41697-41704 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T82981 | 41823-41829 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T6219 | 41918-41924 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T88827 | 41951-41955 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T83956 | 42022-42026 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T11227 | 42053-42058 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T70724 | 42609-42612 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T22187 | 42994-42996 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T61490 | 42997-43007 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T33609 | 43008-43032 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T72503 | 43033-43035 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T84826 | 43051-43062 | CHEBI:86228;CHEBI:86228 | denotes | 3]dioxol-4- |
| T77669 | 43062-43065 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T74326 | 43065-43071 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T68910 | 43074-43076 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T29834 | 43076-43082 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T61527 | 43082-43097 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrophenyl) |
| T2636 | 43097-43103 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T77144 | 43103-43104 | CHEBI:86228;CHEBI:86228 | denotes | ] |
| T5108 | 43104-43109 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T26563 | 43110-43116 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T54685 | 43118-43119 | CHEBI:86228;CHEBI:86228 | denotes | 4 |
| T28095 | 43126-43127 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T7577 | 43127-43145 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T76522 | 43145-43146 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T62588 | 43146-43149 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T93366 | 43150-43161 | CHEBI:53233;CHEBI:53233 | denotes | -5-{[(tert- |
| T84385 | 43161-43179 | CHEBI:28714;CHEBI:28714 | denotes | butyldimethylsilyl |
| T90566 | 43179-43180 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T91292 | 43180-43183 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T24654 | 43184-43190 | CHEBI:16625;CHEBI:16625 | denotes | methyl |
| T77065 | 43191-43203 | CHEBI:53233;CHEBI:53233 | denotes | oxolan-2-yl] |
| T32349 | 43204-43206 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T22971 | 43207-43212 | CHEBI:17939;CHEBI:17939 | denotes | purin |
| T77363 | 43212-43215 | CHEBI:17369;CHEBI:17369 | denotes | -6- |
| T35102 | 43215-43220 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T87653 | 43231-43239 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T87411 | 43313-43321 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T67786 | 43325-43327 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T2415 | 43327-43333 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T47993 | 43333-43354 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrobenazaldehyde |
| T2831 | 43413-43424 | CHEBI:15366;CHEBI:15366 | denotes | acetic acid |
| T81538 | 43502-43508 | CHEBI:35607;CHEBI:35607 | denotes | sodium |
| T68096 | 43509-43530 | CHEBI:28621;CHEBI:28621 | denotes | triacetoxyborohydride |
| T17174 | 43608-43616 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T52438 | 43672-43679 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T1797 | 43680-43686 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T62375 | 43692-43699 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T33887 | 43818-43824 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T87343 | 43913-43919 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T10295 | 43946-43950 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T78188 | 44011-44015 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T12440 | 44044-44049 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T3563 | 44624-44627 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T64879 | 45034-45036 | CHEBI:30756;CHEBI:30756 | denotes | 9H |
| T88899 | 45037-45047 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T82697 | 45048-45072 | CHEBI:53233;CHEBI:53233 | denotes | -2,2-dimethyl-tetrahydro |
| T35641 | 45073-45075 | CHEBI:53233;CHEBI:53233 | denotes | 2H |
| T69144 | 45091-45105 | CHEBI:53233;CHEBI:53233 | denotes | 3]dioxol-4-yl] |
| T20449 | 45105-45111 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T23911 | 45114-45129 | CHEBI:53233;CHEBI:53233 | denotes | 4-chlorophenyl) |
| T40117 | 45129-45135 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T73260 | 45135-45136 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T51819 | 45136-45141 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T92376 | 45142-45148 | CHEBI:42241;CHEBI:42241 | denotes | ethoxy |
| T50880 | 45149-45152 | CHEBI:53233;CHEBI:53233 | denotes | -4- |
| T51295 | 45158-45159 | CHEBI:53233;CHEBI:53233 | denotes | - |
| T94273 | 45178-45181 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T25408 | 45182-45187 | CHEBI:82321;CHEBI:82321 | denotes | -5-{[ |
| T3979 | 45187-45188 | CHEBI:53233;CHEBI:53233 | denotes | ( |
| T73466 | 45192-45211 | CHEBI:82321;CHEBI:82321 | denotes | -butyldimethylsilyl |
| T40247 | 45211-45212 | CHEBI:53233;CHEBI:53233 | denotes | ) |
| T61904 | 45212-45215 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T98027 | 45216-45222 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T11285 | 45223-45229 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T85202 | 45229-45230 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T30710 | 45230-45231 | CHEBI:82321;CHEBI:82321 | denotes | 2 |
| T40090 | 45231-45232 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T11465 | 45232-45234 | CHEBI:82321;CHEBI:82321 | denotes | yl |
| T36791 | 45236-45238 | CHEBI:29238;CHEBI:29238 | denotes | 9H |
| T58221 | 45247-45252 | CHEBI:32952;CHEBI:32952 | denotes | amine |
| T88984 | 45263-45271 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T47720 | 45343-45361 | CHEBI:28105;CHEBI:28105 | denotes | chlorobenzaldehyde |
| T55812 | 45418-45429 | CHEBI:15366;CHEBI:15366 | denotes | acetic acid |
| T35920 | 45507-45513 | CHEBI:35607;CHEBI:35607 | denotes | sodium |
| T25301 | 45514-45535 | CHEBI:28621;CHEBI:28621 | denotes | triacetoxyborohydride |
| T82736 | 45613-45621 | CHEBI:75958;CHEBI:75958 | denotes | solution |
| T62757 | 45677-45684 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T3173 | 45685-45691 | CHEBI:32139;CHEBI:32139 | denotes | NaHCO3 |
| T55909 | 45697-45704 | CHEBI:15377;CHEBI:15377 | denotes | aqueous |
| T40813 | 45823-45829 | CHEBI:34683;CHEBI:34683 | denotes | Na2SO4 |
| T94720 | 45918-45924 | CHEBI:30563;CHEBI:30563 | denotes | silica |
| T85547 | 45951-45955 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T43861 | 46027-46031 | CHEBI:32145;CHEBI:32145 | denotes | MeOH |
| T67038 | 46063-46068 | CHEBI:30808;CHEBI:30808 | denotes | CDCl3 |
| T80677 | 46580-46583 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T17925 | 46980-46995 | CHEBI:50488;CHEBI:50488 | denotes | dihydroxyoxolan |
| T82388 | 46996-46997 | CHEBI:53233;CHEBI:53233 | denotes | 2 |
| T10723 | 46998-47001 | CHEBI:53233;CHEBI:53233 | denotes | yl] |
| T18753 | 47001-47007 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T64138 | 47038-47048 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T73883 | 47050-47052 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T72492 | 47052-47059 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T63934 | 47060-47061 | CHEBI:34018;CHEBI:34018 | denotes | 5 |
| T56249 | 47063-47076 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T30756 | 47077-47083 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T28674 | 47083-47084 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T56815 | 47084-47085 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T26876 | 47085-47088 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T17690 | 47088-47089 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T8379 | 47089-47092 | CHEBI:15533;CHEBI:15533 | denotes | oxy |
| T16867 | 47102-47115 | CHEBI:23132;CHEBI:23132 | denotes | chlorobenzene |
| T31770 | 47115-47116 | CHEBI:34674;CHEBI:34674 | denotes | - |
| T99552 | 47116-47118 | CHEBI:28714;CHEBI:28714 | denotes | 1- |
| T7605 | 47118-47129 | CHEBI:35358;CHEBI:35358 | denotes | sulfonamide |
| T88840 | 47218-47230 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T96112 | 47900-47903 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T41134 | 48240-48241 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T27334 | 48246-48249 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T20136 | 48250-48260 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T73618 | 48262-48264 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T76408 | 48264-48271 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T70567 | 48275-48288 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T85384 | 48289-48295 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T6101 | 48295-48296 | CHEBI:15533;CHEBI:15533 | denotes | - |
| T32228 | 48296-48297 | CHEBI:53233;CHEBI:53233 | denotes | 3 |
| T62461 | 48297-48300 | CHEBI:15533;CHEBI:15533 | denotes | -yl |
| T28904 | 48300-48301 | CHEBI:53233;CHEBI:53233 | denotes | ] |
| T40535 | 48301-48304 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T45088 | 48305-48310 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T66662 | 48313-48315 | CHEBI:86228;CHEBI:86228 | denotes | 4- |
| T71841 | 48315-48321 | CHEBI:47853;CHEBI:47853 | denotes | chloro |
| T70937 | 48321-48335 | CHEBI:86228;CHEBI:86228 | denotes | -3-nitrophenyl |
| T41213 | 48336-48342 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T22878 | 48343-48348 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T6558 | 48349-48355 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T11187 | 48356-48363 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T58590 | 48364-48366 | CHEBI:52029;CHEBI:52029 | denotes | 3, |
| T86321 | 48366-48368 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T9071 | 48368-48372 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T84625 | 48461-48473 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T93629 | 49214-49217 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T42837 | 49571-49572 | CHEBI:30756;CHEBI:30756 | denotes | - |
| T19570 | 49577-49580 | CHEBI:30756;CHEBI:30756 | denotes | -9H |
| T87896 | 49581-49591 | CHEBI:30756;CHEBI:30756 | denotes | purin-9-yl |
| T41919 | 49593-49595 | CHEBI:34018;CHEBI:34018 | denotes | 4- |
| T35781 | 49595-49602 | CHEBI:43176;CHEBI:43176 | denotes | hydroxy |
| T28345 | 49606-49619 | CHEBI:24712;CHEBI:24712 | denotes | hydroxymethyl |
| T91129 | 49620-49626 | CHEBI:26911;CHEBI:26911 | denotes | oxolan |
| T74192 | 49627-49631 | CHEBI:53233;CHEBI:53233 | denotes | 3-yl |
| T18333 | 49632-49635 | CHEBI:29354;CHEBI:29354 | denotes | oxy |
| T87515 | 49636-49641 | CHEBI:37807;CHEBI:37807 | denotes | ethyl |
| T86156 | 49644-49646 | CHEBI:53233;CHEBI:53233 | denotes | 4- |
| T66842 | 49659-49665 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T35149 | 49666-49671 | CHEBI:46882;CHEBI:46882 | denotes | amino |
| T54819 | 49672-49678 | CHEBI:29309;CHEBI:29309 | denotes | methyl |
| T37692 | 49679-49686 | CHEBI:26911;CHEBI:26911 | denotes | oxolane |
| T17466 | 49691-49695 | CHEBI:23824;CHEBI:23824 | denotes | diol |
| T44819 | 49784-49796 | CHEBI:38472;CHEBI:38472 | denotes | acetonitrile |
| T53973 | 50520-50523 | CHEBI:36927;CHEBI:36927 | denotes | 13C |
| T78244 | 50809-50819 | GO:0010467 | denotes | Expression |
| T24440 | 50861-50869 | SP_10 | denotes | SARS-CoV |
| T39744 | 50870-50875 | PR:000000125 | denotes | nsp14 |
| T11149 | 50880-50885 | SP_6;NCBITaxon:9606 | denotes | human |
| T17814 | 51007-51015 | SO:0000155 | denotes | plasmids |
| T90318 | 51035-51044 | GO:0010467 | denotes | expressed |
| T4563 | 51048-51055 | NCBITaxon:562 | denotes | E. coli |
| T38822 | 51119-51127 | NCBITaxon:7742 | denotes | Vaccinia |
| T96822 | 51128-51133 | NCBITaxon:10239 | denotes | virus |
| T77113 | 51157-51164 | GO:0032991 | denotes | complex |
| T18522 | 51325-51327 | CHEBI:29238;CHEBI:29238 | denotes | 3H |
| T89446 | 51488-51495 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T7568 | 51503-51507 | CHEBI:9754;CHEBI:9754 | denotes | Tris |
| T90528 | 51508-51511 | CHEBI:17883;CHEBI:17883 | denotes | HCl |
| T32618 | 51527-51530 | CHEBI:18320;CHEBI:18320 | denotes | DTT |
| T80620 | 51537-51542 | CHEBI:6636;CHEBI:6636 | denotes | MgCl2 |
| T65164 | 51564-51566 | CHEBI:29238;CHEBI:29238 | denotes | 3H |
| T99852 | 51638-51646 | SP_10 | denotes | SARS-CoV |
| T89465 | 51647-51652 | PR:000000125 | denotes | nsp14 |
| T92733 | 51662-51670 | NCBITaxon:7742 | denotes | vaccinia |
| T32742 | 51671-51676 | NCBITaxon:10239 | denotes | virus |
| T40449 | 51712-51717 | SP_6;NCBITaxon:9606 | denotes | human |
| T9798 | 51732-51737 | PR:O43148 | denotes | hRNMT |
| T22704 | 51782-51791 | CHEBI:36357;CHEBI:36357 | denotes | compounds |
| T3161 | 51810-51814 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T66008 | 51825-51829 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T46228 | 51960-51964 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T24685 | 51976-51984 | CHEBI:60004;CHEBI:60004 | denotes | mixtures |
| T53961 | 52049-52054 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T66324 | 52084-52101 | CHEBI:35702;CHEBI:35702 | denotes | diethylaminoethyl |
| T70177 | 52236-52252 | CHEBI:63050;CHEBI:63050 | denotes | ammonium formate |
| T31019 | 52272-52277 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T60694 | 52292-52299 | CHEBI:16236;CHEBI:16236 | denotes | ethanol |
| T18203 | 52362-52364 | CHEBI:29238;CHEBI:29238 | denotes | 3H |
| T42093 | 52680-52688 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T57780 | 53019-53026 | CHEBI:60004;CHEBI:60004 | denotes | mixture |
| T34965 | 53054-53059 | CHEBI:46756;CHEBI:46756 | denotes | HEPES |
| T92372 | 53077-53081 | CHEBI:26710;CHEBI:26710 | denotes | NaCl |
| T1859 | 53086-53098 | CHEBI:51461;CHEBI:51461 | denotes | SYPRO orange |
| T58900 | 53099-53102 | CHEBI:37958;CHEBI:37958 | denotes | dye |
| T44590 | 53122-53130 | SP_10 | denotes | SARS-CoV |
| T5318 | 53131-53136 | PR:000000125 | denotes | nsp14 |
| T72733 | 53154-53162 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T95077 | 53192-53196 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T84187 | 53200-53205 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T34151 | 53261-53269 | CHEBI:36357;CHEBI:36357 | denotes | compound |
| T68043 | 53297-53300 | CHEBI:37958;CHEBI:37958 | denotes | dye |
| T29086 | 53547-53551 | CHEBI:51231;CHEBI:51231 | denotes | DMSO |
| T76544 | 53624-53631 | GO:0032508 | denotes | melting |
| T4088 | 54115-54123 | SP_10 | denotes | SARS-CoV |
| T99586 | 54223-54227 | CHEBI:24870;CHEBI:24870 | denotes | ions |
| T11834 | 54250-54258 | SP_10 | denotes | SARS-CoV |
| T76206 | 54259-54264 | PR:000000125 | denotes | nsp14 |
| T36442 | 54767-54775 | SP_10 | denotes | SARS-CoV |
| T73230 | 54776-54781 | PR:000000125 | denotes | nsp14 |
| T49995 | 54814-54822 | SP_10 | denotes | SARS-CoV |
| T87774 | 54823-54828 | PR:000000125 | denotes | nsp14 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T102 | 50852-50860 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T103 | 50886-50889 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T104 | 50981-50990 | Body_part | denotes | histidine | http://purl.org/sig/ont/fma/fma82755 |
| T105 | 51021-51029 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T106 | 51170-51174 | Body_part | denotes | mRNA | http://purl.org/sig/ont/fma/fma67122 |
| T107 | 51338-51341 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T108 | 51630-51633 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T109 | 51718-51721 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T110 | 51854-51857 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T111 | 52188-52191 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T112 | 52372-52391 | Body_part | denotes | transfer to the RNA | http://purl.org/sig/ont/fma/fma67127 |
| T113 | 52388-52391 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T114 | 52835-52842 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T115 | 53137-53144 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T116 | 53232-53239 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T117 | 54265-54272 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T118 | 54386-54393 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T119 | 54657-54659 | Body_part | denotes | Å3 | http://purl.org/sig/ont/fma/fma66599 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 561 | 182-186 | Chemical | denotes | DIEA | |
| 562 | 206-221 | Chemical | denotes | calcium hydride | |
| 563 | 284-290 | Chemical | denotes | silica | MESH:D012822 |
| 564 | 814-827 | Chemical | denotes | Dinucleosides | |
| 565 | 982-987 | Chemical | denotes | CH3CN | |
| 566 | 999-1004 | Chemical | denotes | TEAAc | |
| 567 | 1021-1026 | Chemical | denotes | CH3CN | |
| 568 | 1038-1043 | Chemical | denotes | TEEAc | |
| 569 | 510-514 | Disease | denotes | HRMS | |
| 580 | 1302-1331 | Chemical | denotes | 5′-amino-2′,3′-isopropylidene | |
| 581 | 1332-1341 | Chemical | denotes | adenosine | MESH:D000241 |
| 582 | 1355-1358 | Chemical | denotes | DMF | |
| 583 | 1383-1387 | Chemical | denotes | Et3N | |
| 584 | 1420-1448 | Chemical | denotes | nitrobenzenesufonyl chloride | |
| 585 | 1535-1540 | Chemical | denotes | argon | MESH:D001128 |
| 586 | 1573-1578 | Chemical | denotes | brine | MESH:C017082 |
| 587 | 1692-1698 | Chemical | denotes | Na2SO4 | |
| 588 | 1762-1766 | Chemical | denotes | Et2O | |
| 589 | 1771-1774 | Chemical | denotes | DCM | |
| 613 | 2022-2031 | Chemical | denotes | adenosine | MESH:D000241 |
| 614 | 2065-2095 | Chemical | denotes | 4-nitrobenzenesufonyl chloride | |
| 615 | 2159-2163 | Chemical | denotes | MeOH | |
| 616 | 2164-2167 | Chemical | denotes | DCM | |
| 617 | 2170-2172 | Chemical | denotes | 1H | |
| 618 | 2187-2193 | Chemical | denotes | DMSO‑d | |
| 619 | 2220-2222 | Chemical | denotes | 1H | |
| 620 | 2239-2241 | Chemical | denotes | 2H | MESH:D003903 |
| 621 | 2253-2255 | Chemical | denotes | 1H | |
| 622 | 2267-2269 | Chemical | denotes | 1H | |
| 623 | 2286-2288 | Chemical | denotes | 2H | MESH:D003903 |
| 624 | 2304-2306 | Chemical | denotes | 2H | MESH:D003903 |
| 625 | 2330-2332 | Chemical | denotes | 1H | |
| 626 | 2365-2367 | Chemical | denotes | 1H | |
| 627 | 2400-2402 | Chemical | denotes | 1H | |
| 628 | 2435-2437 | Chemical | denotes | 1H | |
| 629 | 2454-2456 | Chemical | denotes | 2H | MESH:D003903 |
| 630 | 2468-2470 | Chemical | denotes | 3H | MESH:D014316 |
| 631 | 2482-2484 | Chemical | denotes | 3H | MESH:D014316 |
| 632 | 2487-2490 | Chemical | denotes | 13C | MESH:C000615229 |
| 633 | 2505-2513 | Chemical | denotes | DMSO‑d 6 | |
| 634 | 2656-2667 | Chemical | denotes | C19H22N7O7S | |
| 635 | 2629-2633 | Disease | denotes | HRMS | |
| 644 | 2810-2813 | Chemical | denotes | DMF | |
| 645 | 2883-2888 | Chemical | denotes | K2CO3 | MESH:C037593 |
| 646 | 2939-2944 | Chemical | denotes | argon | MESH:D001128 |
| 647 | 2984-2989 | Chemical | denotes | water | MESH:D014867 |
| 648 | 3103-3109 | Chemical | denotes | Na2SO4 | |
| 649 | 3198-3208 | Chemical | denotes | silica gel | MESH:D058428 |
| 650 | 3231-3235 | Chemical | denotes | MeOH | |
| 651 | 3239-3242 | Chemical | denotes | DCM | |
| 656 | 3699-3703 | Chemical | denotes | MeOH | |
| 657 | 3704-3707 | Chemical | denotes | DCM | |
| 658 | 4522-4538 | Chemical | denotes | C43H65N12O11SSi2 | |
| 659 | 4495-4499 | Disease | denotes | HRMS | |
| 676 | 4884-4887 | Chemical | denotes | DMF | |
| 677 | 4906-4911 | Chemical | denotes | K2CO3 | MESH:C037593 |
| 678 | 4944-4954 | Chemical | denotes | thiophenol | MESH:C042983 |
| 679 | 5033-5038 | Chemical | denotes | argon | MESH:D001128 |
| 680 | 5078-5081 | Chemical | denotes | DCM | |
| 681 | 5118-5122 | Chemical | denotes | NaOH | |
| 682 | 5178-5181 | Chemical | denotes | DCM | |
| 683 | 5245-5250 | Chemical | denotes | brine | MESH:C017082 |
| 684 | 5263-5269 | Chemical | denotes | Na2SO4 | |
| 685 | 5358-5368 | Chemical | denotes | silica gel | MESH:D058428 |
| 686 | 5392-5396 | Chemical | denotes | MeOH | |
| 687 | 5400-5403 | Chemical | denotes | DCM | |
| 688 | 5476-5480 | Chemical | denotes | MeOH | |
| 689 | 5481-5484 | Chemical | denotes | DCM | |
| 690 | 6201-6215 | Chemical | denotes | C37H62N11O7Si2 | |
| 691 | 6174-6178 | Disease | denotes | HRMS | |
| 703 | 6391-6394 | Chemical | denotes | TFA | MESH:D014269 |
| 704 | 6398-6403 | Chemical | denotes | water | MESH:D014867 |
| 705 | 6488-6492 | Chemical | denotes | MeOH | |
| 706 | 6571-6574 | Chemical | denotes | NH3 | |
| 707 | 6578-6582 | Chemical | denotes | MeOH | |
| 708 | 6660-6670 | Chemical | denotes | silica gel | MESH:D058428 |
| 709 | 6721-6733 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 710 | 6737-6742 | Chemical | denotes | TEAAc | |
| 711 | 6853-6858 | Chemical | denotes | water | MESH:D014867 |
| 712 | 6859-6866 | Chemical | denotes | dioxane | MESH:C025223 |
| 713 | 6480-6487 | Disease | denotes | TLC DCM | MESH:D002311 |
| 727 | 7160-7172 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 728 | 7176-7181 | Chemical | denotes | TEAAc | |
| 729 | 7320-7322 | Chemical | denotes | 1H | |
| 730 | 7337-7345 | Chemical | denotes | DMSO‑d 6 | |
| 731 | 7358-7360 | Chemical | denotes | 1H | |
| 732 | 7372-7374 | Chemical | denotes | 1H | |
| 733 | 7386-7388 | Chemical | denotes | 1H | |
| 734 | 7400-7402 | Chemical | denotes | 1H | |
| 735 | 7417-7419 | Chemical | denotes | 2H | MESH:D003903 |
| 736 | 7704-7707 | Chemical | denotes | 13C | MESH:C000615229 |
| 737 | 7722-7728 | Chemical | denotes | DMSO‑d | |
| 738 | 7902-7913 | Chemical | denotes | C22H30N11O7 | |
| 739 | 7875-7879 | Disease | denotes | HRMS | |
| 759 | 8326-8329 | Chemical | denotes | DCM | |
| 760 | 8347-8355 | Chemical | denotes | aldehyde | MESH:D000447 |
| 761 | 8401-8404 | Chemical | denotes | DCM | |
| 762 | 8416-8427 | Chemical | denotes | acetic acid | MESH:D019342 |
| 763 | 8509-8514 | Chemical | denotes | argon | MESH:D001128 |
| 764 | 8516-8544 | Chemical | denotes | sodium triacetoxyborohydride | |
| 765 | 8568-8570 | Chemical | denotes | eq | |
| 766 | 8647-8650 | Chemical | denotes | DCM | |
| 767 | 8693-8699 | Chemical | denotes | NaHCO3 | MESH:D017693 |
| 768 | 8746-8749 | Chemical | denotes | DCM | |
| 769 | 8813-8818 | Chemical | denotes | brine | MESH:C017082 |
| 770 | 8831-8837 | Chemical | denotes | Na2SO4 | |
| 771 | 8926-8936 | Chemical | denotes | silica gel | MESH:D058428 |
| 772 | 8959-8963 | Chemical | denotes | MeOH | |
| 773 | 8967-8970 | Chemical | denotes | DCM | |
| 774 | 9024-9028 | Chemical | denotes | MeOH | |
| 775 | 9029-9032 | Chemical | denotes | DCM | |
| 776 | 9902-9917 | Chemical | denotes | C52H87N12O13Si2 | |
| 777 | 9875-9879 | Disease | denotes | HRMS | |
| 792 | 10237-10240 | Chemical | denotes | TFA | MESH:D014269 |
| 793 | 10253-10258 | Chemical | denotes | water | MESH:D014867 |
| 794 | 10358-10363 | Chemical | denotes | water | MESH:D014867 |
| 795 | 10389-10393 | Chemical | denotes | LiOH | |
| 796 | 10508-10511 | Chemical | denotes | HCl | MESH:D006851 |
| 797 | 10639-10645 | Chemical | denotes | silica | MESH:D012822 |
| 798 | 10657-10660 | Chemical | denotes | C18 | MESH:C109760 |
| 799 | 10706-10718 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 800 | 10722-10727 | Chemical | denotes | TEAAc | |
| 801 | 10838-10843 | Chemical | denotes | water | MESH:D014867 |
| 802 | 11375-11378 | Chemical | denotes | 13C | MESH:C000615229 |
| 803 | 11393-11396 | Chemical | denotes | D2O | |
| 804 | 11591-11602 | Chemical | denotes | C26H37N12O9 | |
| 805 | 11564-11568 | Disease | denotes | HRMS | |
| 812 | 11933-11945 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 813 | 11949-11954 | Chemical | denotes | TEAAc | |
| 814 | 12629-12632 | Chemical | denotes | 13C | MESH:C000615229 |
| 815 | 12647-12650 | Chemical | denotes | D2O | |
| 816 | 12846-12857 | Chemical | denotes | C27H39N12O9 | |
| 817 | 12819-12823 | Disease | denotes | HRMS | |
| 830 | 13173-13176 | Chemical | denotes | TFA | MESH:D014269 |
| 831 | 13190-13195 | Chemical | denotes | water | MESH:D014867 |
| 832 | 13309-13312 | Chemical | denotes | NH3 | |
| 833 | 13316-13320 | Chemical | denotes | MeOH | |
| 834 | 13466-13476 | Chemical | denotes | silica gel | MESH:D058428 |
| 835 | 13533-13545 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 836 | 13549-13554 | Chemical | denotes | TEAAc | |
| 837 | 13665-13670 | Chemical | denotes | water | MESH:D014867 |
| 838 | 14230-14233 | Chemical | denotes | 13C | MESH:C000615229 |
| 839 | 14248-14251 | Chemical | denotes | D2O | |
| 840 | 14446-14457 | Chemical | denotes | C26H38N13O8 | |
| 841 | 14419-14423 | Disease | denotes | HRMS | |
| 847 | 14597-14600 | Chemical | denotes | NMP | MESH:C038678 |
| 848 | 14908-14914 | Chemical | denotes | Na2SO4 | |
| 849 | 15003-15013 | Chemical | denotes | silica gel | MESH:D058428 |
| 850 | 15036-15040 | Chemical | denotes | MeOH | |
| 851 | 15044-15047 | Chemical | denotes | DCM | |
| 864 | 15411-15424 | Chemical | denotes | 1-bromobutane | MESH:C047757 |
| 865 | 15482-15486 | Chemical | denotes | MeOH | |
| 866 | 15487-15490 | Chemical | denotes | DCM | |
| 867 | 15498-15500 | Chemical | denotes | 1H | |
| 868 | 15515-15520 | Chemical | denotes | CDCl3 | |
| 869 | 15533-15535 | Chemical | denotes | 2H | MESH:D003903 |
| 870 | 15547-15549 | Chemical | denotes | 1H | |
| 871 | 15561-15563 | Chemical | denotes | 1H | |
| 872 | 15587-15589 | Chemical | denotes | 1H | |
| 873 | 15613-15615 | Chemical | denotes | 1H | |
| 874 | 16402-16416 | Chemical | denotes | C46H72N11O7Si2 | |
| 875 | 16375-16379 | Disease | denotes | HRMS | |
| 890 | 16775-16798 | Chemical | denotes | 1-bromo-3-phenylpropane | |
| 891 | 16856-16860 | Chemical | denotes | MeOH | |
| 892 | 16861-16864 | Chemical | denotes | DCM | |
| 893 | 16871-16873 | Chemical | denotes | 1H | |
| 894 | 16888-16893 | Chemical | denotes | CDCl3 | |
| 895 | 16906-16908 | Chemical | denotes | 1H | |
| 896 | 16920-16922 | Chemical | denotes | 1H | |
| 897 | 16934-16936 | Chemical | denotes | 1H | |
| 898 | 16948-16950 | Chemical | denotes | 1H | |
| 899 | 16967-16969 | Chemical | denotes | 5H | |
| 900 | 16993-16995 | Chemical | denotes | 1H | |
| 901 | 17019-17021 | Chemical | denotes | 1H | |
| 902 | 17784-17798 | Chemical | denotes | C46H72N11O7Si2 | |
| 903 | 17757-17761 | Disease | denotes | HRMS | |
| 909 | 18167-18189 | Chemical | denotes | methyl-4-bromobutyrate | |
| 910 | 18248-18252 | Chemical | denotes | MeOH | |
| 911 | 18253-18256 | Chemical | denotes | DCM | |
| 912 | 19173-19187 | Chemical | denotes | C42H70N11O9Si2 | |
| 913 | 19146-19150 | Disease | denotes | HRMS | |
| 919 | 19741-19743 | Chemical | denotes | 2H | MESH:D003903 |
| 920 | 20189-20192 | Chemical | denotes | 13C | MESH:C000615229 |
| 921 | 20207-20215 | Chemical | denotes | DMSO‑d 6 | |
| 922 | 20412-20423 | Chemical | denotes | C26H38N11O7 | |
| 923 | 20385-20389 | Disease | denotes | HRMS | |
| 937 | 20729-20741 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 938 | 20745-20750 | Chemical | denotes | TEAAc | |
| 939 | 20888-20890 | Chemical | denotes | 1H | |
| 940 | 20905-20913 | Chemical | denotes | DMSO‑d 6 | |
| 941 | 20926-20928 | Chemical | denotes | 1H | |
| 942 | 20940-20942 | Chemical | denotes | 1H | |
| 943 | 20954-20956 | Chemical | denotes | 1H | |
| 944 | 20968-20970 | Chemical | denotes | 1H | |
| 945 | 20986-20988 | Chemical | denotes | 2H | MESH:D003903 |
| 946 | 21434-21437 | Chemical | denotes | 13C | MESH:C000615229 |
| 947 | 21452-21460 | Chemical | denotes | DMSO‑d 6 | |
| 948 | 21657-21668 | Chemical | denotes | C26H38N11O7 | |
| 949 | 21630-21634 | Disease | denotes | HRMS | |
| 963 | 21985-21997 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 964 | 22001-22006 | Chemical | denotes | TEAAc | |
| 965 | 22145-22147 | Chemical | denotes | 1H | |
| 966 | 22162-22170 | Chemical | denotes | DMSO‑d 6 | |
| 967 | 22183-22185 | Chemical | denotes | 1H | |
| 968 | 22197-22199 | Chemical | denotes | 1H | |
| 969 | 22211-22213 | Chemical | denotes | 1H | |
| 970 | 22225-22227 | Chemical | denotes | 1H | |
| 971 | 22243-22245 | Chemical | denotes | 2H | MESH:D003903 |
| 972 | 22691-22694 | Chemical | denotes | 13C | MESH:C000615229 |
| 973 | 22709-22717 | Chemical | denotes | DMSO‑d 6 | |
| 974 | 22921-22932 | Chemical | denotes | C27H38N11O9 | |
| 975 | 22894-22898 | Disease | denotes | HRMS | |
| 991 | 23216-23219 | Chemical | denotes | TFA | MESH:D014269 |
| 992 | 23234-23239 | Chemical | denotes | water | MESH:D014867 |
| 993 | 23342-23347 | Chemical | denotes | water | MESH:D014867 |
| 994 | 23365-23369 | Chemical | denotes | LiOH | |
| 995 | 23488-23491 | Chemical | denotes | HCl | MESH:D006851 |
| 996 | 23625-23631 | Chemical | denotes | silica | MESH:D012822 |
| 997 | 23643-23646 | Chemical | denotes | C18 | MESH:C109760 |
| 998 | 23692-23704 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 999 | 23708-23713 | Chemical | denotes | TEAAc | |
| 1000 | 23824-23829 | Chemical | denotes | water | MESH:D014867 |
| 1001 | 23834-23845 | Chemical | denotes | 1,4-dioxane | MESH:C025223 |
| 1002 | 24353-24356 | Chemical | denotes | 13C | MESH:C000615229 |
| 1003 | 24371-24374 | Chemical | denotes | D2O | |
| 1004 | 24570-24581 | Chemical | denotes | C26H37N12O9 | |
| 1005 | 24543-24547 | Disease | denotes | HRMS | |
| 1021 | 24904-24916 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1022 | 24920-24925 | Chemical | denotes | TEAAc | |
| 1023 | 25064-25066 | Chemical | denotes | 1H | |
| 1024 | 25081-25087 | Chemical | denotes | DMSO‑d | |
| 1025 | 25102-25104 | Chemical | denotes | 1H | |
| 1026 | 25116-25118 | Chemical | denotes | 1H | |
| 1027 | 25135-25137 | Chemical | denotes | 2H | MESH:D003903 |
| 1028 | 25149-25151 | Chemical | denotes | 1H | |
| 1029 | 25163-25165 | Chemical | denotes | 1H | |
| 1030 | 25182-25184 | Chemical | denotes | 2H | MESH:D003903 |
| 1031 | 25200-25202 | Chemical | denotes | 2H | MESH:D003903 |
| 1032 | 25513-25516 | Chemical | denotes | 13C | MESH:C000615229 |
| 1033 | 25531-25539 | Chemical | denotes | DMSO‑d 6 | |
| 1034 | 25740-25753 | Chemical | denotes | C28H33N12O11S | |
| 1035 | 25713-25717 | Disease | denotes | HRMS | |
| 1051 | 25997-26006 | Chemical | denotes | adenosine | MESH:D000241 |
| 1052 | 26040-26080 | Chemical | denotes | 4-methoxy-2-nitrobenzenesufonyl chloride | |
| 1053 | 26144-26148 | Chemical | denotes | MeOH | |
| 1054 | 26149-26152 | Chemical | denotes | DCM | |
| 1055 | 26155-26157 | Chemical | denotes | 1H | |
| 1056 | 26172-26180 | Chemical | denotes | DMSO‑d 6 | |
| 1057 | 26205-26207 | Chemical | denotes | 1H | |
| 1058 | 26219-26221 | Chemical | denotes | 1H | |
| 1059 | 26233-26235 | Chemical | denotes | 1H | |
| 1060 | 26259-26261 | Chemical | denotes | 1H | |
| 1061 | 26285-26287 | Chemical | denotes | 1H | |
| 1062 | 26551-26554 | Chemical | denotes | 13C | MESH:C000615229 |
| 1063 | 26569-26577 | Chemical | denotes | DMSO‑d 6 | |
| 1064 | 26740-26751 | Chemical | denotes | C20H24N7O8S | |
| 1065 | 26713-26717 | Disease | denotes | HRMS | |
| 1081 | 26995-27004 | Chemical | denotes | adenosine | MESH:D000241 |
| 1082 | 27038-27078 | Chemical | denotes | 2-methoxy-4-nitrobenzenesufonyl chloride | |
| 1083 | 27142-27146 | Chemical | denotes | MeOH | |
| 1084 | 27147-27150 | Chemical | denotes | DCM | |
| 1085 | 27153-27155 | Chemical | denotes | 1H | |
| 1086 | 27170-27176 | Chemical | denotes | DMSO‑d | |
| 1087 | 27203-27205 | Chemical | denotes | 1H | |
| 1088 | 27217-27219 | Chemical | denotes | 1H | |
| 1089 | 27231-27233 | Chemical | denotes | 1H | |
| 1090 | 27250-27252 | Chemical | denotes | 2H | MESH:D003903 |
| 1091 | 27289-27291 | Chemical | denotes | 1H | |
| 1092 | 27516-27519 | Chemical | denotes | 13C | MESH:C000615229 |
| 1093 | 27534-27542 | Chemical | denotes | DMSO‑d 6 | |
| 1094 | 27705-27716 | Chemical | denotes | C20H24N7O8S | |
| 1095 | 27678-27682 | Disease | denotes | HRMS | |
| 1118 | 27933-27962 | Chemical | denotes | 5′-amino-2′,3′-isopropylidene | |
| 1119 | 27963-27972 | Chemical | denotes | adenosine | MESH:D000241 |
| 1120 | 28015-28018 | Chemical | denotes | DMF | |
| 1121 | 28038-28042 | Chemical | denotes | Et3N | |
| 1122 | 28073-28121 | Chemical | denotes | 2-nitro-4-trifluoromethylbenzenesufonyl chloride | |
| 1123 | 28240-28245 | Chemical | denotes | argon | MESH:D001128 |
| 1124 | 28303-28308 | Chemical | denotes | water | MESH:D014867 |
| 1125 | 28450-28456 | Chemical | denotes | Na2SO4 | |
| 1126 | 28545-28555 | Chemical | denotes | silica gel | MESH:D058428 |
| 1127 | 28578-28582 | Chemical | denotes | MeOH | |
| 1128 | 28586-28589 | Chemical | denotes | DCM | |
| 1129 | 28651-28655 | Chemical | denotes | MeOH | |
| 1130 | 28656-28662 | Chemical | denotes | CH2Cl2 | |
| 1131 | 28665-28667 | Chemical | denotes | 1H | |
| 1132 | 28682-28688 | Chemical | denotes | DMSO‑d | |
| 1133 | 28715-28717 | Chemical | denotes | 1H | |
| 1134 | 28741-28743 | Chemical | denotes | 1H | |
| 1135 | 28755-28757 | Chemical | denotes | 1H | |
| 1136 | 28769-28771 | Chemical | denotes | 1H | |
| 1137 | 28808-28810 | Chemical | denotes | 1H | |
| 1138 | 29289-29302 | Chemical | denotes | C20H21N7O7SF3 | |
| 1139 | 29262-29266 | Disease | denotes | HRMS | |
| 1156 | 29545-29554 | Chemical | denotes | adenosine | MESH:D000241 |
| 1157 | 29588-29627 | Chemical | denotes | 4-chloro-3-nitrobenzenesufonyl chloride | |
| 1158 | 29691-29695 | Chemical | denotes | MeOH | |
| 1159 | 29696-29702 | Chemical | denotes | CH2Cl2 | |
| 1160 | 29705-29707 | Chemical | denotes | 1H | |
| 1161 | 29722-29728 | Chemical | denotes | DMSO‑d | |
| 1162 | 29743-29745 | Chemical | denotes | 1H | |
| 1163 | 29769-29771 | Chemical | denotes | 1H | |
| 1164 | 29783-29785 | Chemical | denotes | 1H | |
| 1165 | 29797-29799 | Chemical | denotes | 1H | |
| 1166 | 29836-29838 | Chemical | denotes | 1H | |
| 1167 | 29862-29864 | Chemical | denotes | 1H | |
| 1168 | 30074-30077 | Chemical | denotes | 13C | MESH:C000615229 |
| 1169 | 30092-30100 | Chemical | denotes | DMSO‑d 6 | |
| 1170 | 30264-30277 | Chemical | denotes | C19H21N7O7SCl | |
| 1171 | 30237-30241 | Disease | denotes | HRMS | |
| 1178 | 30729-30733 | Chemical | denotes | MeOH | |
| 1179 | 30734-30737 | Chemical | denotes | DCM | |
| 1180 | 31296-31299 | Chemical | denotes | 18H | |
| 1181 | 31316-31319 | Chemical | denotes | 12H | |
| 1182 | 31626-31642 | Chemical | denotes | C47H67N12O12SSi2 | |
| 1183 | 31599-31603 | Disease | denotes | HRMS | |
| 1192 | 32097-32101 | Chemical | denotes | MeOH | |
| 1193 | 32102-32105 | Chemical | denotes | DCM | |
| 1194 | 32108-32110 | Chemical | denotes | 1H | |
| 1195 | 32125-32130 | Chemical | denotes | CDCl3 | |
| 1196 | 32143-32145 | Chemical | denotes | 1H | |
| 1197 | 32157-32159 | Chemical | denotes | 1H | |
| 1198 | 32909-32925 | Chemical | denotes | C47H67N12O12SSi2 | |
| 1199 | 32882-32886 | Disease | denotes | HRMS | |
| 1204 | 33388-33392 | Chemical | denotes | MeOH | |
| 1205 | 33393-33396 | Chemical | denotes | DCM | |
| 1206 | 34393-34411 | Chemical | denotes | C44H64N12O11SF3Si2 | |
| 1207 | 34366-34370 | Disease | denotes | HRMS | |
| 1213 | 34865-34869 | Chemical | denotes | MeOH | |
| 1214 | 34870-34873 | Chemical | denotes | DCM | |
| 1215 | 35407-35410 | Chemical | denotes | 12H | |
| 1216 | 35711-35729 | Chemical | denotes | C43H64N12O11SSi2Cl | |
| 1217 | 35684-35688 | Disease | denotes | HRMS | |
| 1246 | 36092-36104 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1247 | 36108-36113 | Chemical | denotes | TEAAc | |
| 1248 | 36253-36255 | Chemical | denotes | 1H | |
| 1249 | 36270-36276 | Chemical | denotes | DMSO‑d | |
| 1250 | 36291-36293 | Chemical | denotes | 1H | |
| 1251 | 36305-36307 | Chemical | denotes | 1H | |
| 1252 | 36319-36321 | Chemical | denotes | 2H | MESH:D003903 |
| 1253 | 36345-36347 | Chemical | denotes | 1H | |
| 1254 | 36384-36386 | Chemical | denotes | 1H | |
| 1255 | 36402-36404 | Chemical | denotes | 2H | MESH:D003903 |
| 1256 | 36420-36422 | Chemical | denotes | 2H | MESH:D003903 |
| 1257 | 36459-36461 | Chemical | denotes | 1H | |
| 1258 | 36485-36487 | Chemical | denotes | 1H | |
| 1259 | 36511-36513 | Chemical | denotes | 1H | |
| 1260 | 36529-36531 | Chemical | denotes | 1H | |
| 1261 | 36547-36549 | Chemical | denotes | 1H | |
| 1262 | 36573-36575 | Chemical | denotes | 1H | |
| 1263 | 36591-36593 | Chemical | denotes | 1H | |
| 1264 | 36617-36619 | Chemical | denotes | 1H | |
| 1265 | 36643-36645 | Chemical | denotes | 1H | |
| 1266 | 36662-36664 | Chemical | denotes | 1H | |
| 1267 | 36681-36683 | Chemical | denotes | 2H | MESH:D003903 |
| 1268 | 36707-36709 | Chemical | denotes | 1H | |
| 1269 | 36721-36723 | Chemical | denotes | 3H | MESH:D014316 |
| 1270 | 36740-36742 | Chemical | denotes | 3H | MESH:D014316 |
| 1271 | 36759-36761 | Chemical | denotes | 5H | |
| 1272 | 37009-37022 | Chemical | denotes | C29H35N12O12S | |
| 1273 | 36982-36986 | Disease | denotes | HRMS | |
| 1302 | 37355-37367 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1303 | 37371-37376 | Chemical | denotes | TEAAc | |
| 1304 | 37516-37518 | Chemical | denotes | 1H | |
| 1305 | 37533-37539 | Chemical | denotes | DMSO‑d | |
| 1306 | 37554-37556 | Chemical | denotes | 1H | |
| 1307 | 37568-37570 | Chemical | denotes | 1H | |
| 1308 | 37582-37584 | Chemical | denotes | 2H | MESH:D003903 |
| 1309 | 37608-37610 | Chemical | denotes | 1H | |
| 1310 | 37647-37649 | Chemical | denotes | 1H | |
| 1311 | 37665-37667 | Chemical | denotes | 2H | MESH:D003903 |
| 1312 | 37683-37685 | Chemical | denotes | 2H | MESH:D003903 |
| 1313 | 37722-37724 | Chemical | denotes | 1H | |
| 1314 | 37748-37750 | Chemical | denotes | 1H | |
| 1315 | 37774-37776 | Chemical | denotes | 1H | |
| 1316 | 37792-37794 | Chemical | denotes | 1H | |
| 1317 | 37810-37812 | Chemical | denotes | 1H | |
| 1318 | 37836-37838 | Chemical | denotes | 1H | |
| 1319 | 37854-37856 | Chemical | denotes | 1H | |
| 1320 | 37880-37882 | Chemical | denotes | 1H | |
| 1321 | 37906-37908 | Chemical | denotes | 1H | |
| 1322 | 37925-37927 | Chemical | denotes | 1H | |
| 1323 | 37944-37946 | Chemical | denotes | 2H | MESH:D003903 |
| 1324 | 37970-37972 | Chemical | denotes | 1H | |
| 1325 | 37984-37986 | Chemical | denotes | 3H | MESH:D014316 |
| 1326 | 38003-38005 | Chemical | denotes | 3H | MESH:D014316 |
| 1327 | 38022-38024 | Chemical | denotes | 5H | |
| 1328 | 38274-38287 | Chemical | denotes | C29H35N12O12S | |
| 1329 | 38247-38251 | Disease | denotes | HRMS | |
| 1345 | 38627-38639 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1346 | 38643-38648 | Chemical | denotes | TEAAc | |
| 1347 | 38788-38790 | Chemical | denotes | 1H | |
| 1348 | 38805-38811 | Chemical | denotes | DMSO‑d | |
| 1349 | 38838-38840 | Chemical | denotes | 1H | |
| 1350 | 38852-38854 | Chemical | denotes | 1H | |
| 1351 | 38866-38868 | Chemical | denotes | 1H | |
| 1352 | 38892-38894 | Chemical | denotes | 1H | |
| 1353 | 38906-38908 | Chemical | denotes | 1H | |
| 1354 | 38920-38922 | Chemical | denotes | 1H | |
| 1355 | 38959-38961 | Chemical | denotes | 1H | |
| 1356 | 38977-38979 | Chemical | denotes | 2H | MESH:D003903 |
| 1357 | 39623-39631 | Chemical | denotes | DMSO‑d 6 | |
| 1358 | 39643-39647 | Disease | denotes | HRMS | |
| 1359 | 39670-39679 | CellLine | denotes | C29H32N12 | CVCL:0189 |
| 1374 | 40017-40029 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1375 | 40033-40038 | Chemical | denotes | TEAAc | |
| 1376 | 40178-40180 | Chemical | denotes | 1H | |
| 1377 | 40195-40201 | Chemical | denotes | DMSO‑d | |
| 1378 | 40228-40230 | Chemical | denotes | 1H | |
| 1379 | 40242-40244 | Chemical | denotes | 1H | |
| 1380 | 40256-40258 | Chemical | denotes | 1H | |
| 1381 | 40271-40273 | Chemical | denotes | 1H | |
| 1382 | 40286-40288 | Chemical | denotes | 1H | |
| 1383 | 40325-40327 | Chemical | denotes | 1H | |
| 1384 | 40351-40353 | Chemical | denotes | 1H | |
| 1385 | 40369-40371 | Chemical | denotes | 2H | MESH:D003903 |
| 1386 | 40956-40971 | Chemical | denotes | C28H32N12O11SCl | |
| 1387 | 40929-40933 | Disease | denotes | HRMS | |
| 1404 | 41351-41354 | Chemical | denotes | DCM | |
| 1405 | 41372-41376 | Chemical | denotes | Et3N | |
| 1406 | 41406-41438 | Chemical | denotes | 4-chlorobenzenesulfonyl chloride | |
| 1407 | 41556-41561 | Chemical | denotes | argon | MESH:D001128 |
| 1408 | 41631-41634 | Chemical | denotes | DCM | |
| 1409 | 41677-41683 | Chemical | denotes | NaHCO3 | MESH:D017693 |
| 1410 | 41730-41733 | Chemical | denotes | DCM | |
| 1411 | 41797-41802 | Chemical | denotes | brine | MESH:C017082 |
| 1412 | 41823-41829 | Chemical | denotes | Na2SO4 | |
| 1413 | 41918-41928 | Chemical | denotes | silica gel | MESH:D058428 |
| 1414 | 41951-41955 | Chemical | denotes | MeOH | |
| 1415 | 41959-41962 | Chemical | denotes | DCM | |
| 1416 | 42022-42026 | Chemical | denotes | MeOH | |
| 1417 | 42027-42033 | Chemical | denotes | CH2Cl2 | |
| 1418 | 42892-42909 | Chemical | denotes | C43H65N11O9SSi2Cl | |
| 1419 | 42865-42869 | Disease | denotes | HRMS | |
| 1446 | 43288-43291 | Chemical | denotes | DCE | |
| 1447 | 43325-43354 | Chemical | denotes | 4-chloro-3-nitrobenazaldehyde | |
| 1448 | 43396-43399 | Chemical | denotes | DCE | |
| 1449 | 43413-43424 | Chemical | denotes | acetic acid | MESH:D019342 |
| 1450 | 43495-43500 | Chemical | denotes | argon | MESH:D001128 |
| 1451 | 43502-43530 | Chemical | denotes | sodium triacetoxyborohydride | |
| 1452 | 43634-43637 | Chemical | denotes | DCM | |
| 1453 | 43680-43686 | Chemical | denotes | NaHCO3 | MESH:D017693 |
| 1454 | 43725-43728 | Chemical | denotes | DCM | |
| 1455 | 43792-43797 | Chemical | denotes | brine | MESH:C017082 |
| 1456 | 43818-43824 | Chemical | denotes | Na2SO4 | |
| 1457 | 43913-43923 | Chemical | denotes | silica gel | MESH:D058428 |
| 1458 | 43946-43950 | Chemical | denotes | MeOH | |
| 1459 | 43954-43957 | Chemical | denotes | DCM | |
| 1460 | 44011-44015 | Chemical | denotes | MeOH | |
| 1461 | 44016-44019 | Chemical | denotes | DCM | |
| 1462 | 44027-44029 | Chemical | denotes | 1H | |
| 1463 | 44044-44049 | Chemical | denotes | CDCl3 | |
| 1464 | 44062-44064 | Chemical | denotes | 1H | |
| 1465 | 44076-44078 | Chemical | denotes | 1H | |
| 1466 | 44090-44092 | Chemical | denotes | 1H | |
| 1467 | 44108-44110 | Chemical | denotes | 2H | MESH:D003903 |
| 1468 | 44127-44129 | Chemical | denotes | 2H | MESH:D003903 |
| 1469 | 44145-44147 | Chemical | denotes | 2H | MESH:D003903 |
| 1470 | 44935-44951 | Chemical | denotes | C44H66N12O9Si2Cl | |
| 1471 | 44908-44912 | Disease | denotes | HRMS | |
| 1490 | 45320-45323 | Chemical | denotes | DCE | |
| 1491 | 45341-45361 | Chemical | denotes | 4-chlorobenzaldehyde | MESH:C052044 |
| 1492 | 45403-45406 | Chemical | denotes | DCE | |
| 1493 | 45418-45429 | Chemical | denotes | acetic acid | MESH:D019342 |
| 1494 | 45500-45505 | Chemical | denotes | argon | MESH:D001128 |
| 1495 | 45507-45535 | Chemical | denotes | sodium triacetoxyborohydride | |
| 1496 | 45639-45642 | Chemical | denotes | DCM | |
| 1497 | 45685-45691 | Chemical | denotes | NaHCO3 | MESH:D017693 |
| 1498 | 45730-45733 | Chemical | denotes | DCM | |
| 1499 | 45797-45802 | Chemical | denotes | brine | MESH:C017082 |
| 1500 | 45823-45829 | Chemical | denotes | Na2SO4 | |
| 1501 | 45918-45928 | Chemical | denotes | silica gel | MESH:D058428 |
| 1502 | 45951-45955 | Chemical | denotes | MeOH | |
| 1503 | 45959-45962 | Chemical | denotes | DCM | |
| 1504 | 46027-46031 | Chemical | denotes | MeOH | |
| 1505 | 46032-46038 | Chemical | denotes | CH2Cl2 | |
| 1506 | 46877-46893 | Chemical | denotes | C44H67N11O7Si2Cl | |
| 1507 | 46850-46854 | Disease | denotes | HRMS | |
| 1523 | 47218-47230 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1524 | 47234-47239 | Chemical | denotes | TEAAc | |
| 1525 | 47379-47381 | Chemical | denotes | 1H | |
| 1526 | 47396-47402 | Chemical | denotes | DMSO‑d | |
| 1527 | 47417-47419 | Chemical | denotes | 1H | |
| 1528 | 47431-47433 | Chemical | denotes | 1H | |
| 1529 | 47446-47448 | Chemical | denotes | 1H | |
| 1530 | 47461-47463 | Chemical | denotes | 1H | |
| 1531 | 47480-47482 | Chemical | denotes | 2H | MESH:D003903 |
| 1532 | 47499-47501 | Chemical | denotes | 2H | MESH:D003903 |
| 1533 | 47517-47519 | Chemical | denotes | 2H | MESH:D003903 |
| 1534 | 47900-47903 | Chemical | denotes | 13C | MESH:C000615229 |
| 1535 | 47918-47926 | Chemical | denotes | DMSO‑d 6 | |
| 1536 | 48127-48141 | Chemical | denotes | C28H33N11O9SCl | |
| 1537 | 48100-48104 | Disease | denotes | HRMS | |
| 1556 | 48461-48473 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1557 | 48477-48482 | Chemical | denotes | TEAAc | |
| 1558 | 48622-48624 | Chemical | denotes | 1H | |
| 1559 | 48639-48645 | Chemical | denotes | DMSO‑d | |
| 1560 | 48660-48662 | Chemical | denotes | 1H | |
| 1561 | 48674-48676 | Chemical | denotes | 1H | |
| 1562 | 48688-48690 | Chemical | denotes | 1H | |
| 1563 | 48702-48704 | Chemical | denotes | 1H | |
| 1564 | 48728-48730 | Chemical | denotes | 1H | |
| 1565 | 48754-48756 | Chemical | denotes | 1H | |
| 1566 | 48793-48795 | Chemical | denotes | 1H | |
| 1567 | 48811-48813 | Chemical | denotes | 2H | MESH:D003903 |
| 1568 | 48829-48831 | Chemical | denotes | 2H | MESH:D003903 |
| 1569 | 48855-48857 | Chemical | denotes | 1H | |
| 1570 | 48881-48883 | Chemical | denotes | 1H | |
| 1571 | 48900-48902 | Chemical | denotes | 2H | MESH:D003903 |
| 1572 | 49432-49436 | Disease | denotes | HRMS | |
| 1573 | 49459-49468 | CellLine | denotes | C29H34N12 | CVCL:0189 |
| 1587 | 49784-49796 | Chemical | denotes | acetonitrile | MESH:C032159 |
| 1588 | 49800-49805 | Chemical | denotes | TEAAc | |
| 1589 | 49945-49947 | Chemical | denotes | 1H | |
| 1590 | 49962-49970 | Chemical | denotes | DMSO‑d 6 | |
| 1591 | 49983-49985 | Chemical | denotes | 1H | |
| 1592 | 49997-49999 | Chemical | denotes | 1H | |
| 1593 | 50011-50013 | Chemical | denotes | 1H | |
| 1594 | 50025-50027 | Chemical | denotes | 1H | |
| 1595 | 50043-50045 | Chemical | denotes | 2H | MESH:D003903 |
| 1596 | 50520-50523 | Chemical | denotes | 13C | MESH:C000615229 |
| 1597 | 50538-50544 | Chemical | denotes | DMSO‑d | |
| 1598 | 50755-50768 | Chemical | denotes | C29H35N11O7Cl | |
| 1599 | 50728-50732 | Disease | denotes | HRMS | |
| 1601 | 50981-50990 | Chemical | denotes | histidine | MESH:D006639 |
| 1618 | 51325-51327 | Chemical | denotes | 3H | MESH:D014316 |
| 1619 | 51503-51507 | Chemical | denotes | Tris | |
| 1620 | 51508-51511 | Chemical | denotes | HCl | MESH:D006851 |
| 1621 | 51527-51530 | Chemical | denotes | DTT | MESH:D004229 |
| 1622 | 51537-51542 | Chemical | denotes | MgCl2 | MESH:D015636 |
| 1623 | 51564-51566 | Chemical | denotes | 3H | MESH:D014316 |
| 1624 | 51810-51814 | Chemical | denotes | DMSO | MESH:D004121 |
| 1625 | 51825-51829 | Chemical | denotes | DMSO | MESH:D004121 |
| 1626 | 51960-51964 | Chemical | denotes | DMSO | MESH:D004121 |
| 1627 | 52049-52054 | Chemical | denotes | water | MESH:D014867 |
| 1628 | 52084-52101 | Chemical | denotes | diethylaminoethyl | |
| 1629 | 52103-52107 | Chemical | denotes | DEAE | |
| 1630 | 52236-52252 | Chemical | denotes | ammonium formate | MESH:C030544 |
| 1631 | 52272-52277 | Chemical | denotes | water | MESH:D014867 |
| 1632 | 52292-52299 | Chemical | denotes | ethanol | MESH:D000431 |
| 1633 | 52362-52364 | Chemical | denotes | 3H | MESH:D014316 |
| 1640 | 53054-53059 | Chemical | denotes | HEPES | MESH:D006531 |
| 1641 | 53077-53081 | Chemical | denotes | NaCl | MESH:D012965 |
| 1642 | 53086-53098 | Chemical | denotes | SYPRO orange | |
| 1643 | 53192-53196 | Chemical | denotes | DMSO | MESH:D004121 |
| 1644 | 53200-53205 | Chemical | denotes | water | MESH:D014867 |
| 1645 | 53547-53551 | Chemical | denotes | DMSO | MESH:D004121 |
| 1647 | 54427-54436 | Chemical | denotes | hydrogens | MESH:D006859 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T98 | 720-723 | Disease | denotes | LPG | http://purl.obolibrary.org/obo/MONDO_0012725 |
| T99 | 802-805 | Disease | denotes | TCC | http://purl.obolibrary.org/obo/MONDO_0008521 |
| T100 | 50861-50869 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T101 | 51119-51127 | Disease | denotes | Vaccinia | http://purl.obolibrary.org/obo/MONDO_0002595 |
| T102 | 51638-51646 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T103 | 51662-51670 | Disease | denotes | vaccinia | http://purl.obolibrary.org/obo/MONDO_0002595 |
| T104 | 53122-53130 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T105 | 54115-54123 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T106 | 54250-54258 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T107 | 54767-54775 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T108 | 54814-54822 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T255 | 593-594 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T256 | 658-659 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T257 | 718-719 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T258 | 737-738 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T259 | 828-832 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 1–16 |
| T260 | 861-862 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T261 | 884-886 | http://purl.obolibrary.org/obo/CLO_0002878 | denotes | ec |
| T262 | 1013-1014 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T263 | 1052-1053 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T264 | 1140-1144 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 1–16 |
| T265 | 1234-1235 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T266 | 1267-1269 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T267 | 1275-1277 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T268 | 1288-1289 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T269 | 1640-1647 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T270 | 1640-1647 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T271 | 1807-1808 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T272 | 1964-1966 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T273 | 1985-1986 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T274 | 2097-2099 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T275 | 2130-2131 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T276 | 2669-2672 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T277 | 2725-2726 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T278 | 2771-2772 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T279 | 2785-2787 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T280 | 3051-3058 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T281 | 3051-3058 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T282 | 3589-3590 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T283 | 3597-3599 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T284 | 3663-3664 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T285 | 4540-4543 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T286 | 4825-4826 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T287 | 4956-4958 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T288 | 5211-5218 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T289 | 5211-5218 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T290 | 5447-5448 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T291 | 6217-6220 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T292 | 6310-6314 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 3, 5 |
| T293 | 6444-6447 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 3–6 |
| T294 | 6643-6644 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T295 | 6700-6701 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T296 | 6895-6896 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T297 | 7133-7134 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T298 | 7250-7251 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T299 | 7915-7918 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T300 | 8260-8262 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T301 | 8267-8268 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T302 | 8779-8786 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T303 | 8779-8786 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T304 | 8980-8982 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T305 | 8988-8994 | http://purl.obolibrary.org/obo/CLO_0007701 | denotes | mg, 93 |
| T306 | 9000-9001 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T307 | 9919-9922 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T308 | 10169-10171 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T309 | 10622-10623 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T310 | 10679-10680 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T311 | 10870-10871 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T312 | 11604-11607 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T313 | 11870-11872 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T314 | 11906-11907 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T315 | 12002-12004 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T316 | 12023-12024 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T317 | 12859-12862 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T318 | 13104-13106 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T319 | 13108-13111 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 116 |
| T320 | 13449-13450 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T321 | 13506-13507 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T322 | 13685-13691 | http://purl.obolibrary.org/obo/CLO_0007698 | denotes | mg, 38 |
| T323 | 13697-13698 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T324 | 14459-14462 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T325 | 14567-14568 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T326 | 14856-14863 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T327 | 14856-14863 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T328 | 15081-15082 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T329 | 15458-15459 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T330 | 16418-16421 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T331 | 16832-16833 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T332 | 17800-17803 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T333 | 18224-18225 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T334 | 19189-19192 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T335 | 19457-19458 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T336 | 19574-19575 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T337 | 20425-20428 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T338 | 20702-20703 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T339 | 20818-20819 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T340 | 21670-21673 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T341 | 21926-21929 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 116 |
| T342 | 21958-21959 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T343 | 22075-22076 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T344 | 22934-22937 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T345 | 23608-23609 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T346 | 23665-23666 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T347 | 23857-23859 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T348 | 23864-23866 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T349 | 23872-23873 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T350 | 24583-24586 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T351 | 24877-24878 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T352 | 24973-24975 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T353 | 24994-24995 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T354 | 25755-25758 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T355 | 25960-25961 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T356 | 26115-26116 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T357 | 26753-26756 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T358 | 26937-26939 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T359 | 26958-26959 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T360 | 27080-27082 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T361 | 27113-27114 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T362 | 27718-27721 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T363 | 27919-27920 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T364 | 28390-28397 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T365 | 28390-28397 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T366 | 28611-28613 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
| T367 | 28619-28620 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T368 | 29304-29307 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T369 | 29508-29509 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T370 | 29662-29663 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T371 | 30279-30282 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T372 | 30621-30622 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T373 | 30673-30675 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T374 | 30694-30695 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T375 | 31249-31252 | http://purl.obolibrary.org/obo/CLO_0050298 | denotes | 10H |
| T376 | 31644-31647 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T377 | 31989-31990 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T378 | 31996-31998 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T379 | 32062-32063 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T380 | 32514-32517 | http://purl.obolibrary.org/obo/CLO_0050298 | denotes | 10H |
| T381 | 32927-32930 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T382 | 33282-33283 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T383 | 33353-33354 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T384 | 34413-34416 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T385 | 34757-34766 | http://purl.obolibrary.org/obo/CLO_0001811 | denotes | B with 29 |
| T386 | 34830-34831 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T387 | 35731-35734 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T388 | 36065-36066 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T389 | 36183-36184 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T390 | 37024-37027 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T391 | 37268-37270 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T392 | 37328-37329 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T393 | 37414-37416 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T394 | 37446-37447 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T395 | 38289-38292 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T396 | 38600-38601 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T397 | 38690-38692 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T398 | 38718-38719 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T399 | 39687-39690 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T400 | 39958-39961 | http://purl.obolibrary.org/obo/CLO_0001053 | denotes | 121 |
| T401 | 39990-39991 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T402 | 40108-40109 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T403 | 40973-40976 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T404 | 41285-41287 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T405 | 41292-41293 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T406 | 41763-41770 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T407 | 41763-41770 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T408 | 41972-41974 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T409 | 41992-41993 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T410 | 42911-42914 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T411 | 43222-43224 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T412 | 43229-43230 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T413 | 43311-43312 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T414 | 43356-43358 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T415 | 43758-43765 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T416 | 43758-43765 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T417 | 43967-43969 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T418 | 43973-43974 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T419 | 44953-44956 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T420 | 45254-45256 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T421 | 45261-45262 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T422 | 45431-45433 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T423 | 45763-45770 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T424 | 45763-45770 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T425 | 45972-45974 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T426 | 45978-45979 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T427 | 46895-46898 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T428 | 47155-47157 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T429 | 47191-47192 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T430 | 47288-47290 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T431 | 47309-47310 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T432 | 48143-48146 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T433 | 48398-48400 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T434 | 48434-48435 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T435 | 48552-48553 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T436 | 49474-49477 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T437 | 49721-49723 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T438 | 49757-49758 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T439 | 49847-49849 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
| T440 | 49875-49876 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T441 | 50770-50773 | http://purl.obolibrary.org/obo/CLO_0007706 | denotes | M+H |
| T442 | 50880-50885 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T443 | 50963-50964 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T444 | 51128-51133 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T445 | 51671-51676 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T446 | 51702-51704 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
| T447 | 51712-51717 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T448 | 52139-52140 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T449 | 52170-52181 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | Instruments |
| T450 | 52424-52425 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T451 | 52739-52747 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T452 | 52981-52983 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T453 | 53416-53417 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T454 | 53448-53449 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T455 | 53594-53595 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T456 | 54025-54026 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T457 | 54045-54046 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T458 | 54153-54154 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T459 | 54545-54546 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T460 | 54623-54624 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T461 | 54657-54659 | http://purl.obolibrary.org/obo/CLO_0001577 | denotes | Å3 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T564 | 75-83 | Chemical | denotes | solvents | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T565 | 88-96 | Chemical | denotes | reagents | http://purl.obolibrary.org/obo/CHEBI_33893 |
| T566 | 206-213 | Chemical | denotes | calcium | http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320 |
| T568 | 214-221 | Chemical | denotes | hydride | http://purl.obolibrary.org/obo/CHEBI_29239 |
| T569 | 284-290 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T570 | 720-723 | Chemical | denotes | LPG | http://purl.obolibrary.org/obo/CHEBI_59681 |
| T571 | 802-805 | Chemical | denotes | TCC | http://purl.obolibrary.org/obo/CHEBI_48347 |
| T572 | 850-852 | Chemical | denotes | RP | http://purl.obolibrary.org/obo/CHEBI_141419 |
| T573 | 952-959 | Chemical | denotes | solvent | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T574 | 1006-1012 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T575 | 1045-1051 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T576 | 1290-1298 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T577 | 1305-1310 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T578 | 1317-1331 | Chemical | denotes | isopropylidene | http://purl.obolibrary.org/obo/CHEBI_29858 |
| T579 | 1332-1341 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T580 | 1355-1358 | Chemical | denotes | DMF | http://purl.obolibrary.org/obo/CHEBI_17741 |
| T581 | 1440-1448 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
| T582 | 1481-1488 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T583 | 1535-1540 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T584 | 1563-1568 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T585 | 1617-1622 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T586 | 1692-1698 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T587 | 1771-1774 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T588 | 1847-1868 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T589 | 1849-1854 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T590 | 1874-1882 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T592 | 1926-1932 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T594 | 1936-1948 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T595 | 1951-1962 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T596 | 1995-2000 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T597 | 2007-2021 | Chemical | denotes | isopropylidene | http://purl.obolibrary.org/obo/CHEBI_29858 |
| T598 | 2022-2031 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T599 | 2087-2095 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
| T600 | 2145-2147 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T601 | 2159-2163 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T602 | 2164-2167 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T603 | 2170-2172 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T604 | 2187-2191 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T605 | 2220-2222 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T606 | 2253-2255 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T607 | 2267-2269 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T608 | 2330-2332 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T609 | 2365-2367 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T610 | 2400-2402 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T611 | 2435-2437 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T612 | 2505-2509 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T613 | 2773-2781 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T614 | 2810-2813 | Chemical | denotes | DMF | http://purl.obolibrary.org/obo/CHEBI_17741 |
| T615 | 2866-2868 | Chemical | denotes | KI | http://purl.obolibrary.org/obo/CHEBI_74559|http://purl.obolibrary.org/obo/CHEBI_8346 |
| T617 | 2883-2888 | Chemical | denotes | K2CO3 | http://purl.obolibrary.org/obo/CHEBI_131526 |
| T618 | 2939-2944 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T619 | 2974-2979 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T620 | 2984-2989 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T621 | 3028-3033 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T622 | 3103-3109 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T623 | 3198-3204 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T624 | 3231-3235 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T625 | 3239-3242 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T626 | 3314-3335 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T627 | 3316-3321 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T628 | 3341-3349 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T630 | 3393-3399 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T632 | 3419-3440 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T633 | 3421-3426 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T634 | 3470-3473 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T635 | 3504-3507 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T636 | 3508-3514 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T638 | 3527-3530 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T639 | 3531-3536 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T641 | 3540-3552 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T642 | 3555-3566 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T643 | 3684-3686 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T644 | 3699-3703 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T645 | 3704-3707 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T646 | 3710-3712 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T647 | 3727-3732 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T648 | 3760-3762 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T649 | 3793-3795 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T650 | 3857-3859 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T651 | 3896-3898 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T652 | 3935-3937 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T653 | 3974-3976 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T654 | 4013-4015 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T655 | 4052-4054 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T656 | 4091-4093 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T657 | 4131-4133 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T658 | 4249-4254 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T659 | 4614-4635 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T660 | 4616-4621 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T661 | 4641-4649 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T663 | 4693-4699 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T665 | 4700-4705 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T666 | 4706-4712 | Chemical | denotes | ethoxy | http://purl.obolibrary.org/obo/CHEBI_42241 |
| T667 | 4742-4745 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T668 | 4776-4779 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T669 | 4780-4786 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T671 | 4800-4816 | Chemical | denotes | 9H-purin-6-amine | http://purl.obolibrary.org/obo/CHEBI_16708 |
| T672 | 4811-4816 | Chemical | denotes | amine | http://purl.obolibrary.org/obo/CHEBI_32952 |
| T673 | 4827-4835 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T674 | 4884-4887 | Chemical | denotes | DMF | http://purl.obolibrary.org/obo/CHEBI_17741 |
| T675 | 4906-4911 | Chemical | denotes | K2CO3 | http://purl.obolibrary.org/obo/CHEBI_131526 |
| T676 | 4944-4954 | Chemical | denotes | thiophenol | http://purl.obolibrary.org/obo/CHEBI_48498 |
| T677 | 5033-5038 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T678 | 5053-5060 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T679 | 5078-5081 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T680 | 5118-5122 | Chemical | denotes | NaOH | http://purl.obolibrary.org/obo/CHEBI_32145 |
| T681 | 5123-5131 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T682 | 5178-5181 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T683 | 5263-5269 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T684 | 5358-5364 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T685 | 5392-5396 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T686 | 5400-5403 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T687 | 5462-5464 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T688 | 5476-5480 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T689 | 5481-5484 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T690 | 5487-5489 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T691 | 5504-5509 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T692 | 5522-5524 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T693 | 5536-5538 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T694 | 5550-5552 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T695 | 5564-5566 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T696 | 5609-5611 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T697 | 5648-5650 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T698 | 5667-5669 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T699 | 5686-5688 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T700 | 5744-5746 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T701 | 5784-5786 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T702 | 5824-5826 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T703 | 5961-5966 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T704 | 6391-6394 | Chemical | denotes | TFA | http://purl.obolibrary.org/obo/CHEBI_45892 |
| T705 | 6398-6403 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T706 | 6484-6487 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T707 | 6488-6492 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T708 | 6495-6503 | Chemical | denotes | solvents | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T709 | 6571-6574 | Chemical | denotes | NH3 | http://purl.obolibrary.org/obo/CHEBI_16134 |
| T710 | 6578-6582 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T711 | 6660-6666 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T712 | 6721-6733 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T713 | 6743-6749 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T714 | 6853-6858 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T715 | 6859-6866 | Chemical | denotes | dioxane | http://purl.obolibrary.org/obo/CHEBI_46923 |
| T716 | 6924-6945 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T717 | 6926-6931 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T718 | 6967-6988 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T719 | 6969-6974 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T720 | 6992-6999 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T721 | 7003-7016 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T722 | 7029-7032 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T723 | 7033-7038 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T725 | 7039-7044 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T726 | 7045-7051 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T728 | 7052-7059 | Chemical | denotes | oxolane | http://purl.obolibrary.org/obo/CHEBI_26911 |
| T729 | 7064-7068 | Chemical | denotes | diol | http://purl.obolibrary.org/obo/CHEBI_23824 |
| T730 | 7160-7172 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T731 | 7182-7188 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T732 | 7320-7322 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T733 | 7337-7341 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T734 | 7358-7360 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T735 | 7372-7374 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T736 | 7386-7388 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T737 | 7400-7402 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T738 | 7461-7463 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T739 | 7487-7489 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T740 | 7525-7527 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T741 | 7564-7566 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T742 | 7603-7605 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T743 | 7642-7644 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T744 | 7722-7726 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T745 | 7987-8008 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T746 | 7989-7994 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T747 | 8014-8022 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T749 | 8066-8072 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T751 | 8089-8110 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T752 | 8091-8096 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T753 | 8140-8143 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T754 | 8174-8177 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T755 | 8178-8184 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T757 | 8197-8200 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T758 | 8201-8206 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T760 | 8207-8212 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T761 | 8234-8242 | Chemical | denotes | carbonyl | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T762 | 8243-8248 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T763 | 8249-8258 | Chemical | denotes | butanoate | http://purl.obolibrary.org/obo/CHEBI_17968 |
| T764 | 8269-8277 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T765 | 8326-8329 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T766 | 8347-8355 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T767 | 8401-8404 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T768 | 8416-8427 | Chemical | denotes | acetic acid | http://purl.obolibrary.org/obo/CHEBI_15366 |
| T769 | 8423-8427 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T770 | 8509-8514 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T771 | 8516-8522 | Chemical | denotes | sodium | http://purl.obolibrary.org/obo/CHEBI_26708 |
| T772 | 8622-8629 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T773 | 8647-8650 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T774 | 8693-8699 | Chemical | denotes | NaHCO3 | http://purl.obolibrary.org/obo/CHEBI_32139 |
| T775 | 8746-8749 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T776 | 8831-8837 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T777 | 8926-8932 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T778 | 8959-8963 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T779 | 8967-8970 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T780 | 9015-9017 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T781 | 9024-9028 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T782 | 9029-9032 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T783 | 9040-9042 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T784 | 9057-9062 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T785 | 9075-9077 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T786 | 9089-9091 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T787 | 9103-9105 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T788 | 9117-9119 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T789 | 9143-9145 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T790 | 9169-9171 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T791 | 9222-9224 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T792 | 9260-9262 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T793 | 9299-9301 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T794 | 9318-9320 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T795 | 9357-9359 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T796 | 9397-9399 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T797 | 9473-9475 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T798 | 9492-9494 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T799 | 9606-9611 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T800 | 9985-10006 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T801 | 9987-9992 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T802 | 10033-10039 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T804 | 10056-10077 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T805 | 10058-10063 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T806 | 10081-10088 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T807 | 10092-10105 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T808 | 10118-10121 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T809 | 10122-10127 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T811 | 10128-10133 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T812 | 10237-10240 | Chemical | denotes | TFA | http://purl.obolibrary.org/obo/CHEBI_45892 |
| T813 | 10253-10258 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T814 | 10293-10301 | Chemical | denotes | solvents | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T815 | 10358-10363 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T816 | 10389-10393 | Chemical | denotes | LiOH | http://purl.obolibrary.org/obo/CHEBI_33979 |
| T817 | 10394-10402 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T818 | 10508-10511 | Chemical | denotes | HCl | http://purl.obolibrary.org/obo/CHEBI_17883 |
| T819 | 10512-10520 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T820 | 10526-10533 | Chemical | denotes | solvent | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T821 | 10639-10645 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T822 | 10706-10718 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T823 | 10728-10734 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T824 | 10838-10843 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T825 | 10940-10942 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T826 | 10957-10960 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T827 | 10973-10975 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T828 | 10987-10989 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T829 | 11001-11003 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T830 | 11015-11017 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T831 | 11041-11043 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T832 | 11067-11069 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T833 | 11125-11127 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T834 | 11144-11146 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T835 | 11203-11205 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T836 | 11259-11261 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T837 | 11324-11326 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T838 | 11351-11353 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T839 | 11393-11396 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T840 | 11661-11666 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T841 | 11683-11704 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T842 | 11685-11690 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T843 | 11731-11737 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T845 | 11754-11775 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T846 | 11756-11761 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T847 | 11779-11786 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T848 | 11790-11803 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T849 | 11816-11819 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T850 | 11820-11825 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T852 | 11826-11831 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T853 | 11832-11841 | Chemical | denotes | butanoate | http://purl.obolibrary.org/obo/CHEBI_17968 |
| T854 | 11933-11945 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T855 | 11955-11961 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T856 | 12093-12095 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T857 | 12110-12113 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T858 | 12126-12128 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T859 | 12140-12142 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T860 | 12154-12156 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T861 | 12168-12170 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T862 | 12194-12196 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T863 | 12220-12222 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T864 | 12239-12241 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T865 | 12278-12280 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T866 | 12317-12319 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T867 | 12336-12338 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T868 | 12376-12378 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T869 | 12415-12417 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T870 | 12454-12456 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T871 | 12559-12561 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T872 | 12586-12588 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T873 | 12605-12607 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T874 | 12647-12650 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T875 | 12909-12914 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T876 | 12931-12952 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T877 | 12933-12938 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T878 | 12979-12985 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T880 | 13002-13023 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T881 | 13004-13009 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T882 | 13027-13034 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T883 | 13038-13051 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T884 | 13064-13067 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T885 | 13068-13073 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T887 | 13074-13079 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T888 | 13080-13090 | Chemical | denotes | butanamide | http://purl.obolibrary.org/obo/CHEBI_50724 |
| T889 | 13173-13176 | Chemical | denotes | TFA | http://purl.obolibrary.org/obo/CHEBI_45892 |
| T890 | 13190-13195 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T891 | 13250-13258 | Chemical | denotes | solvents | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T892 | 13309-13312 | Chemical | denotes | NH3 | http://purl.obolibrary.org/obo/CHEBI_16134 |
| T893 | 13316-13320 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T894 | 13364-13372 | Chemical | denotes | solvents | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T895 | 13466-13472 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T896 | 13533-13545 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T897 | 13555-13561 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T898 | 13665-13670 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T899 | 13767-13769 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T900 | 13784-13787 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T901 | 13800-13802 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T902 | 13814-13816 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T903 | 13828-13830 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T904 | 13842-13844 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T905 | 13868-13870 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T906 | 13894-13896 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T907 | 13933-13935 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T908 | 13952-13954 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T909 | 13991-13993 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T910 | 14010-14012 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T911 | 14069-14071 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T912 | 14128-14130 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T913 | 14206-14208 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T914 | 14248-14251 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T915 | 14569-14577 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T916 | 14597-14600 | Chemical | denotes | NMP | http://purl.obolibrary.org/obo/CHEBI_17188|http://purl.obolibrary.org/obo/CHEBI_25608|http://purl.obolibrary.org/obo/CHEBI_7307 |
| T919 | 14644-14651 | Chemical | denotes | bromide | http://purl.obolibrary.org/obo/CHEBI_15858 |
| T920 | 14652-14659 | Chemical | denotes | reagent | http://purl.obolibrary.org/obo/CHEBI_33893 |
| T921 | 14754-14761 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T922 | 14779-14784 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T923 | 14833-14838 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T924 | 14908-14914 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T925 | 15003-15009 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T926 | 15036-15040 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T927 | 15044-15047 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T928 | 15139-15160 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T929 | 15141-15146 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T930 | 15166-15174 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T932 | 15218-15224 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T934 | 15226-15231 | Chemical | denotes | butyl | http://purl.obolibrary.org/obo/CHEBI_41264 |
| T935 | 15232-15237 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T936 | 15238-15244 | Chemical | denotes | ethoxy | http://purl.obolibrary.org/obo/CHEBI_42241 |
| T937 | 15274-15277 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T938 | 15308-15311 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T939 | 15312-15318 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T941 | 15332-15348 | Chemical | denotes | 9H-purin-6-amine | http://purl.obolibrary.org/obo/CHEBI_16708 |
| T942 | 15343-15348 | Chemical | denotes | amine | http://purl.obolibrary.org/obo/CHEBI_32952 |
| T24253 | 15473-15475 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T16296 | 15482-15486 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T3 | 15487-15490 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T98279 | 15498-15500 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T14128 | 15515-15520 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T7839 | 15547-15549 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T62523 | 15561-15563 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T51533 | 15587-15589 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T47370 | 15613-15615 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T35194 | 15670-15672 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T23227 | 15709-15711 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T97352 | 15735-15737 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T68865 | 15793-15795 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T34711 | 15833-15835 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T82490 | 15873-15875 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T26759 | 15951-15953 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T72541 | 16133-16138 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T61383 | 16491-16512 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T13400 | 16493-16498 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T20 | 16518-16526 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T22 | 16570-16576 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T24 | 16593-16598 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T6760 | 16599-16605 | Chemical | denotes | ethoxy | http://purl.obolibrary.org/obo/CHEBI_42241 |
| T96923 | 16635-16638 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T27 | 16669-16672 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T68784 | 16673-16679 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T31890 | 16693-16709 | Chemical | denotes | 9H-purin-6-amine | http://purl.obolibrary.org/obo/CHEBI_16708 |
| T23509 | 16704-16709 | Chemical | denotes | amine | http://purl.obolibrary.org/obo/CHEBI_32952 |
| T71137 | 16777-16782 | Chemical | denotes | bromo | http://purl.obolibrary.org/obo/CHEBI_22927|http://purl.obolibrary.org/obo/CHEBI_47265 |
| T93238 | 16847-16849 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T65053 | 16856-16860 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T36 | 16861-16864 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T9869 | 16871-16873 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T44254 | 16888-16893 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T65997 | 16906-16908 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T46574 | 16920-16922 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T41 | 16934-16936 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T34034 | 16948-16950 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T43 | 16993-16995 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T71874 | 17019-17021 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T45 | 17076-17078 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T85561 | 17115-17117 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T92728 | 17141-17143 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T48306 | 17199-17201 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T8053 | 17239-17241 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T8498 | 17279-17281 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T51 | 17357-17359 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T98021 | 17493-17498 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T53 | 17866-17887 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T18926 | 17868-17873 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T85668 | 17893-17901 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T94799 | 17945-17951 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T45895 | 17968-17989 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T47614 | 17970-17975 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T61 | 18019-18022 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T3622 | 18053-18056 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T97877 | 18057-18063 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T40837 | 18076-18079 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T48012 | 18080-18085 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T30820 | 18086-18091 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T18158 | 18092-18101 | Chemical | denotes | butanoate | http://purl.obolibrary.org/obo/CHEBI_17968 |
| T72997 | 18167-18173 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T73357 | 18239-18241 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T73 | 18248-18252 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T61099 | 18253-18256 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T38107 | 18264-18266 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T76 | 18281-18286 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T45520 | 18299-18301 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T14016 | 18313-18315 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T17378 | 18327-18329 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T66161 | 18341-18343 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T52308 | 18367-18369 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T33388 | 18420-18422 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T83 | 18459-18461 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T95802 | 18485-18487 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T79068 | 18543-18545 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T46465 | 18583-18585 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T71575 | 18623-18625 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T41446 | 18682-18684 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T33129 | 18741-18743 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T78609 | 18897-18902 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T89184 | 19243-19264 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T92 | 19245-19250 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T91758 | 19286-19307 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T94 | 19288-19293 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T35472 | 19311-19318 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T53508 | 19322-19335 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T60043 | 19348-19351 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T11829 | 19352-19357 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T94414 | 19359-19364 | Chemical | denotes | butyl | http://purl.obolibrary.org/obo/CHEBI_41264 |
| T16576 | 19365-19370 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T102 | 19371-19377 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T33703 | 19378-19385 | Chemical | denotes | oxolane | http://purl.obolibrary.org/obo/CHEBI_26911 |
| T105 | 19390-19394 | Chemical | denotes | diol | http://purl.obolibrary.org/obo/CHEBI_23824 |
| T17575 | 19484-19496 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T86424 | 19506-19512 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T108 | 19643-19645 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T24815 | 19660-19664 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T20156 | 19681-19683 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T65687 | 19695-19697 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T8029 | 19709-19711 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T2651 | 19723-19725 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T5457 | 19785-19787 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T115 | 19811-19813 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T28173 | 19856-19858 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T85971 | 19882-19884 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T74956 | 19914-19916 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T36399 | 19946-19948 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T49547 | 19972-19974 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T89992 | 20043-20045 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T35229 | 20207-20211 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T13361 | 20478-20499 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T124 | 20480-20485 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T6426 | 20521-20542 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T126 | 20523-20528 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T6455 | 20546-20553 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T50558 | 20557-20570 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T16045 | 20583-20586 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T28407 | 20587-20592 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T132 | 20609-20614 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T42784 | 20615-20621 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T51078 | 20622-20629 | Chemical | denotes | oxolane | http://purl.obolibrary.org/obo/CHEBI_26911 |
| T95580 | 20634-20638 | Chemical | denotes | diol | http://purl.obolibrary.org/obo/CHEBI_23824 |
| T91685 | 20729-20741 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T55170 | 20751-20757 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T49282 | 20888-20890 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T84039 | 20905-20909 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T94512 | 20926-20928 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T37040 | 20940-20942 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T28951 | 20954-20956 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T27788 | 20968-20970 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T92805 | 21030-21032 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T146 | 21056-21058 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T26862 | 21101-21103 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T40060 | 21127-21129 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T89685 | 21159-21161 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T52261 | 21191-21193 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T151 | 21217-21219 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T60336 | 21288-21290 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T95747 | 21452-21456 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T75415 | 21735-21756 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T64795 | 21737-21742 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T22000 | 21783-21789 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T9251 | 21806-21827 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T90458 | 21808-21813 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T4133 | 21831-21838 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T84907 | 21842-21855 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T71821 | 21868-21871 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T64408 | 21872-21877 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T12886 | 21878-21883 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T97272 | 21884-21893 | Chemical | denotes | butanoate | http://purl.obolibrary.org/obo/CHEBI_17968 |
| T68932 | 21985-21997 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T15587 | 22007-22013 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T169 | 22145-22147 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T170 | 22162-22166 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T28776 | 22183-22185 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T172 | 22197-22199 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T69431 | 22211-22213 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T174 | 22225-22227 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T175 | 22287-22289 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T30683 | 22313-22315 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T177 | 22358-22360 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T84312 | 22384-22386 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T179 | 22416-22418 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T180 | 22448-22450 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T73053 | 22474-22476 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T12938 | 22493-22495 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T92774 | 22512-22514 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T93642 | 22545-22547 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T51448 | 22597-22599 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T186 | 22709-22713 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T52186 | 22992-23013 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T71124 | 22994-22999 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T91179 | 23040-23046 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T191 | 23062-23083 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T25223 | 23064-23069 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T4835 | 23087-23094 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T67895 | 23098-23111 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T64132 | 23124-23127 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T8624 | 23128-23133 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T3060 | 23134-23139 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T19597 | 23140-23153 | Chemical | denotes | butanoic acid | http://purl.obolibrary.org/obo/CHEBI_30772 |
| T17443 | 23149-23153 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T55499 | 23216-23219 | Chemical | denotes | TFA | http://purl.obolibrary.org/obo/CHEBI_45892 |
| T92108 | 23234-23239 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T27273 | 23277-23285 | Chemical | denotes | solvents | http://purl.obolibrary.org/obo/CHEBI_46787 |
| T83132 | 23342-23347 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T14764 | 23365-23369 | Chemical | denotes | LiOH | http://purl.obolibrary.org/obo/CHEBI_33979 |
| T93820 | 23378-23386 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T54370 | 23488-23491 | Chemical | denotes | HCl | http://purl.obolibrary.org/obo/CHEBI_17883 |
| T6531 | 23500-23508 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T80709 | 23625-23631 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T66891 | 23692-23704 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T91062 | 23714-23720 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T90091 | 23824-23829 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T17933 | 23834-23845 | Chemical | denotes | 1,4-dioxane | http://purl.obolibrary.org/obo/CHEBI_47032 |
| T66670 | 23838-23845 | Chemical | denotes | dioxane | http://purl.obolibrary.org/obo/CHEBI_46923 |
| T88233 | 23942-23944 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T216 | 23959-23962 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T68989 | 23975-23977 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T82560 | 23989-23991 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T81404 | 24003-24005 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T12372 | 24017-24019 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T28362 | 24043-24045 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T98794 | 24069-24071 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T15115 | 24088-24090 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T89279 | 24126-24128 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T92999 | 24145-24147 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T58256 | 24164-24166 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T40105 | 24220-24222 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T12935 | 24257-24259 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T229 | 24371-24374 | Chemical | denotes | D2O | http://purl.obolibrary.org/obo/CHEBI_41981 |
| T95728 | 24641-24662 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T231 | 24643-24648 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T88670 | 24689-24695 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T72865 | 24715-24736 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T235 | 24717-24722 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T19593 | 24740-24747 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T73471 | 24751-24764 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T55405 | 24777-24780 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T78555 | 24781-24786 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T241 | 24790-24802 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T19924 | 24805-24816 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T243 | 24904-24916 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T56015 | 24926-24932 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T72768 | 25064-25066 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T91178 | 25081-25085 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T96978 | 25102-25104 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T74178 | 25116-25118 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T87762 | 25149-25151 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T73030 | 25163-25165 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T72407 | 25244-25246 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T22886 | 25270-25272 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T40680 | 25315-25317 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T254 | 25341-25343 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T66835 | 25360-25362 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T28203 | 25386-25388 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T98164 | 25425-25427 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T69540 | 25451-25453 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T259 | 25489-25491 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T63532 | 25531-25535 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T11992 | 25812-25833 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T10378 | 25814-25819 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T88964 | 25839-25847 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T23991 | 25891-25897 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T267 | 25901-25908 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T269 | 25911-25923 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T79814 | 25926-25937 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T91742 | 25970-25975 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T272 | 25982-25996 | Chemical | denotes | isopropylidene | http://purl.obolibrary.org/obo/CHEBI_29858 |
| T33382 | 25997-26006 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T53867 | 26042-26049 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T88523 | 26072-26080 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
| T18075 | 26130-26132 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T66646 | 26144-26148 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T23370 | 26149-26152 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T9964 | 26155-26157 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T47201 | 26172-26176 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T282 | 26205-26207 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T13990 | 26219-26221 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T284 | 26233-26235 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T49293 | 26259-26261 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T27316 | 26285-26287 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T21631 | 26342-26344 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T66889 | 26368-26370 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T289 | 26407-26409 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T45321 | 26446-26448 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T83599 | 26485-26487 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T25831 | 26569-26573 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T43107 | 26810-26831 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T294 | 26812-26817 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T34429 | 26837-26845 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T20605 | 26889-26895 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T63103 | 26899-26906 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T72642 | 26909-26921 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T85919 | 26924-26935 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T82241 | 26968-26973 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T97825 | 26980-26994 | Chemical | denotes | isopropylidene | http://purl.obolibrary.org/obo/CHEBI_29858 |
| T12682 | 26995-27004 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T35906 | 27040-27047 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T308 | 27070-27078 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
| T89906 | 27128-27130 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T37926 | 27142-27146 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T8309 | 27147-27150 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T52192 | 27153-27155 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T313 | 27170-27174 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T43623 | 27203-27205 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T30131 | 27217-27219 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T26042 | 27231-27233 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T4739 | 27289-27291 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T53110 | 27333-27335 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T81829 | 27372-27374 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T83409 | 27411-27413 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T321 | 27450-27452 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T28481 | 27534-27538 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T323 | 27775-27796 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T56849 | 27777-27782 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T61141 | 27802-27810 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T53464 | 27854-27860 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T78954 | 27864-27869 | Chemical | denotes | nitro | http://purl.obolibrary.org/obo/CHEBI_29785 |
| T50310 | 27872-27896 | Chemical | denotes | (trifluoromethyl)benzene | http://purl.obolibrary.org/obo/CHEBI_36810 |
| T81695 | 27873-27888 | Chemical | denotes | trifluoromethyl | http://purl.obolibrary.org/obo/CHEBI_50127 |
| T78167 | 27889-27896 | Chemical | denotes | benzene | http://purl.obolibrary.org/obo/CHEBI_16716 |
| T8343 | 27899-27910 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T334 | 27921-27929 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T49996 | 27936-27941 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T336 | 27948-27962 | Chemical | denotes | isopropylidene | http://purl.obolibrary.org/obo/CHEBI_29858 |
| T66989 | 27963-27972 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T98465 | 28015-28018 | Chemical | denotes | DMF | http://purl.obolibrary.org/obo/CHEBI_17741 |
| T54606 | 28075-28080 | Chemical | denotes | nitro | http://purl.obolibrary.org/obo/CHEBI_29785 |
| T80254 | 28113-28121 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
| T51701 | 28186-28193 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T342 | 28240-28245 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T48319 | 28260-28267 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T60107 | 28285-28290 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T59374 | 28303-28308 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T52962 | 28355-28360 | Chemical | denotes | AcOEt | http://purl.obolibrary.org/obo/CHEBI_27750 |
| T23043 | 28450-28456 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T348 | 28545-28551 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T33545 | 28578-28582 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T55497 | 28586-28589 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T10772 | 28637-28639 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T48310 | 28651-28655 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T39153 | 28665-28667 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T64417 | 28682-28686 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T67452 | 28715-28717 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T2039 | 28741-28743 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T357 | 28755-28757 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T60176 | 28769-28771 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T32588 | 28808-28810 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T70644 | 28874-28876 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T37735 | 28913-28915 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T51184 | 28952-28954 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T71680 | 28991-28993 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T5000 | 29061-29065 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T50217 | 29361-29382 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T43169 | 29363-29368 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T42743 | 29388-29396 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T87205 | 29440-29446 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T25385 | 29450-29456 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T43755 | 29459-29471 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T373 | 29474-29485 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T78338 | 29518-29523 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T86776 | 29530-29544 | Chemical | denotes | isopropylidene | http://purl.obolibrary.org/obo/CHEBI_29858 |
| T376 | 29545-29554 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T92152 | 29590-29596 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T10656 | 29619-29627 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
| T62047 | 29677-29679 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T62948 | 29691-29695 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T13967 | 29705-29707 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T24399 | 29722-29726 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T9330 | 29743-29745 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T73417 | 29769-29771 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T39372 | 29783-29785 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T59648 | 29797-29799 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T66135 | 29836-29838 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T48396 | 29862-29864 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T4269 | 29906-29908 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T13812 | 29945-29947 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T44374 | 29984-29986 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T91535 | 30022-30024 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T95896 | 30092-30096 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T948 | 30336-30357 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T70230 | 30338-30343 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T72752 | 30363-30371 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T89635 | 30415-30421 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T42604 | 30441-30462 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T95901 | 30443-30448 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T11596 | 30492-30495 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T55585 | 30526-30529 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T24974 | 30530-30536 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T69310 | 30549-30552 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T42807 | 30553-30558 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T79697 | 30562-30569 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T87828 | 30572-30584 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T24304 | 30587-30598 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T66918 | 30714-30716 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T68778 | 30729-30733 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T5138 | 30734-30737 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T78755 | 30740-30742 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T62119 | 30757-30762 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T67417 | 30777-30779 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T57690 | 30792-30794 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T97608 | 30806-30808 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T78389 | 30820-30822 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T29195 | 30846-30848 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T73506 | 30872-30874 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T53566 | 30911-30913 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T76589 | 30937-30939 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T80847 | 30995-30997 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T427 | 31034-31036 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T40294 | 31073-31075 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T9376 | 31112-31114 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T430 | 31151-31153 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T91450 | 31190-31192 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T94985 | 31230-31232 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T45648 | 31340-31345 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T434 | 31704-31725 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T42258 | 31706-31711 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T1314 | 31731-31739 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T20595 | 31783-31789 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T440 | 31809-31830 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T93628 | 31811-31816 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T79330 | 31860-31863 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T63252 | 31894-31897 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T65970 | 31898-31904 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T98231 | 31917-31920 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T86005 | 31921-31926 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T59687 | 31930-31937 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T451 | 31940-31952 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T27057 | 31955-31966 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T73729 | 32082-32084 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T36607 | 32097-32101 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T455 | 32102-32105 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T62708 | 32108-32110 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T457 | 32125-32130 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T55837 | 32143-32145 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T14048 | 32157-32159 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T40387 | 32175-32177 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T66826 | 32189-32191 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T462 | 32255-32257 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T53940 | 32273-32275 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T78710 | 32312-32314 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T55173 | 32338-32340 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T13162 | 32377-32379 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T57797 | 32416-32418 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T15479 | 32455-32457 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T27007 | 32495-32497 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T50730 | 32624-32629 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T53880 | 32987-33008 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T31743 | 32989-32994 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T86069 | 33014-33022 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T475 | 33066-33072 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T55020 | 33092-33113 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T478 | 33094-33099 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T42445 | 33143-33146 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T480 | 33177-33180 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T78607 | 33181-33187 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T58556 | 33200-33203 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T51085 | 33204-33209 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T27719 | 33213-33218 | Chemical | denotes | nitro | http://purl.obolibrary.org/obo/CHEBI_29785 |
| T69034 | 33221-33245 | Chemical | denotes | (trifluoromethyl)benzene | http://purl.obolibrary.org/obo/CHEBI_36810 |
| T488 | 33222-33237 | Chemical | denotes | trifluoromethyl | http://purl.obolibrary.org/obo/CHEBI_50127 |
| T30906 | 33238-33245 | Chemical | denotes | benzene | http://purl.obolibrary.org/obo/CHEBI_16716 |
| T19274 | 33248-33259 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T85507 | 33373-33375 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T35836 | 33388-33392 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T17098 | 33393-33396 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T10869 | 33399-33401 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T7681 | 33416-33421 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T18694 | 33434-33436 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T18393 | 33448-33450 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T34872 | 33462-33464 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T85647 | 33488-33490 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T98194 | 33514-33516 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T31716 | 33528-33530 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T35527 | 33567-33569 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T9110 | 33593-33595 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T47865 | 33619-33621 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T13260 | 33676-33678 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T74661 | 33715-33717 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T507 | 33754-33756 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T23051 | 33793-33795 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T509 | 33832-33834 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T510 | 33929-33931 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T511 | 34028-34033 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T87672 | 34473-34494 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T81613 | 34475-34480 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T57553 | 34500-34508 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T97644 | 34552-34558 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T518 | 34578-34599 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T45291 | 34580-34585 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T16592 | 34629-34632 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T69664 | 34663-34666 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T37762 | 34667-34673 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T97095 | 34686-34689 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T74950 | 34690-34695 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T48949 | 34699-34705 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T62330 | 34708-34720 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T67570 | 34723-34734 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T55220 | 34850-34852 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T22091 | 34865-34869 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T99475 | 34870-34873 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T533 | 34876-34878 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T25965 | 34893-34898 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T39525 | 34911-34913 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T99833 | 34925-34927 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T64395 | 34955-34957 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T85135 | 34994-34996 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T18506 | 35020-35022 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T52601 | 35078-35080 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T78849 | 35117-35119 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T542 | 35156-35158 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T93066 | 35195-35197 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T87973 | 35234-35236 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T545 | 35431-35436 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T52264 | 35797-35818 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T51146 | 35799-35804 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T47151 | 35824-35848 | Chemical | denotes | dihydroxytetrahydrofuran | http://purl.obolibrary.org/obo/CHEBI_47019 |
| T69929 | 35854-35860 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T29164 | 35886-35907 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T92393 | 35888-35893 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T553 | 35911-35918 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T39065 | 35922-35935 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T99197 | 35936-35951 | Chemical | denotes | tetrahydrofuran | http://purl.obolibrary.org/obo/CHEBI_26911 |
| T90121 | 35957-35960 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T41179 | 35961-35966 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T82046 | 35970-35977 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T561 | 36092-36104 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T79344 | 36114-36120 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T97724 | 36253-36255 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T35088 | 36270-36274 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T38829 | 36291-36293 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T30702 | 36305-36307 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T567 | 36345-36347 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T63479 | 36384-36386 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T21312 | 36459-36461 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T81599 | 36485-36487 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T10901 | 36511-36513 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T34402 | 36529-36531 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T34533 | 36547-36549 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T25955 | 36573-36575 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T59484 | 36591-36593 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T30216 | 36617-36619 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T16450 | 36643-36645 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T86682 | 36662-36664 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T39834 | 36707-36709 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T79975 | 36782-36786 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T93847 | 37081-37102 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T22848 | 37083-37088 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T51289 | 37129-37135 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T45430 | 37155-37176 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T85865 | 37157-37162 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T63263 | 37180-37187 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T54987 | 37191-37204 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T56820 | 37217-37220 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T33381 | 37221-37226 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T53334 | 37230-37237 | Chemical | denotes | methoxy | http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520 |
| T38495 | 37240-37252 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T38841 | 37255-37266 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T15782 | 37355-37367 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T34792 | 37377-37383 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T78354 | 37516-37518 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T14581 | 37533-37537 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T22965 | 37554-37556 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T55962 | 37568-37570 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T48514 | 37608-37610 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T96071 | 37647-37649 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T88852 | 37722-37724 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T38568 | 37748-37750 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T31277 | 37774-37776 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T84482 | 37792-37794 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T30462 | 37810-37812 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T2044 | 37836-37838 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T90423 | 37854-37856 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T6961 | 37880-37882 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T12338 | 37906-37908 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T52243 | 37925-37927 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T81477 | 37970-37972 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T89255 | 38045-38049 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T616 | 38346-38367 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T96744 | 38348-38353 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T66719 | 38394-38400 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T49061 | 38420-38441 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T27925 | 38422-38427 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T94159 | 38445-38452 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T96765 | 38456-38469 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T53372 | 38482-38485 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T36482 | 38486-38491 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T32993 | 38495-38500 | Chemical | denotes | nitro | http://purl.obolibrary.org/obo/CHEBI_29785 |
| T34326 | 38503-38527 | Chemical | denotes | (trifluoromethyl)benzene | http://purl.obolibrary.org/obo/CHEBI_36810 |
| T629 | 38504-38519 | Chemical | denotes | trifluoromethyl | http://purl.obolibrary.org/obo/CHEBI_50127 |
| T75889 | 38520-38527 | Chemical | denotes | benzene | http://purl.obolibrary.org/obo/CHEBI_16716 |
| T631 | 38530-38541 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T47431 | 38627-38639 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T35557 | 38649-38655 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T37877 | 38788-38790 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T52101 | 38805-38809 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T48273 | 38838-38840 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T637 | 38852-38854 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T22825 | 38866-38868 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T23474 | 38892-38894 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T640 | 38906-38908 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T94081 | 38920-38922 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T8168 | 38959-38961 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T68874 | 39021-39023 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T63267 | 39047-39049 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T93792 | 39073-39075 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T58208 | 39099-39101 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T12607 | 39138-39140 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T94498 | 39164-39166 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T44455 | 39190-39192 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T97308 | 39216-39218 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T97343 | 39242-39244 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T78806 | 39287-39289 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T25804 | 39348-39352 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T68486 | 39623-39627 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T37122 | 39744-39765 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T6392 | 39746-39751 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T60248 | 39792-39798 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T54928 | 39818-39839 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T92031 | 39820-39825 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T4142 | 39843-39850 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T662 | 39854-39867 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T42905 | 39880-39883 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T664 | 39884-39889 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T20583 | 39893-39899 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T88063 | 39902-39914 | Chemical | denotes | nitrobenzene | http://purl.obolibrary.org/obo/CHEBI_27798 |
| T35595 | 39917-39928 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T27886 | 40017-40029 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T670 | 40039-40045 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T32310 | 40178-40180 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T88164 | 40195-40199 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T33091 | 40228-40230 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T35870 | 40242-40244 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T55042 | 40256-40258 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T5281 | 40271-40273 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T43033 | 40286-40288 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T8910 | 40325-40327 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T46731 | 40351-40353 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T78659 | 40412-40414 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T77980 | 40438-40440 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T28166 | 40464-40466 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T77813 | 40509-40511 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T77672 | 40535-40537 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T56894 | 40561-40563 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T4703 | 40587-40589 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T20231 | 40632-40634 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T2314 | 40691-40693 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T51379 | 40733-40737 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T35779 | 41030-41051 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T95569 | 41032-41037 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T55421 | 41057-41065 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T35755 | 41109-41115 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T60423 | 41135-41156 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T29079 | 41137-41142 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T95003 | 41186-41189 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T91402 | 41220-41223 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T56772 | 41224-41230 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T25632 | 41243-41246 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T92641 | 41247-41252 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T56172 | 41256-41269 | Chemical | denotes | chlorobenzene | http://purl.obolibrary.org/obo/CHEBI_28097 |
| T79394 | 41272-41283 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T39178 | 41294-41302 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T7288 | 41351-41354 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T21825 | 41430-41438 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
| T39091 | 41502-41509 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T12679 | 41556-41561 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T62923 | 41631-41634 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T78174 | 41677-41683 | Chemical | denotes | NaHCO3 | http://purl.obolibrary.org/obo/CHEBI_32139 |
| T56606 | 41730-41733 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T38211 | 41823-41829 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T55386 | 41918-41924 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T95902 | 41951-41955 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T64508 | 41959-41962 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T23226 | 42007-42009 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T19017 | 42022-42026 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T17814 | 42036-42038 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T95988 | 42053-42058 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T72152 | 42071-42073 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T724 | 42085-42087 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T43471 | 42099-42101 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T34939 | 42113-42115 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T727 | 42177-42179 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T50503 | 42235-42237 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T2649 | 42274-42276 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T28528 | 42313-42315 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T10272 | 42332-42334 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T66248 | 42371-42373 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T43013 | 42410-42412 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T35561 | 42450-42452 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T70756 | 42509-42511 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T3928 | 42627-42632 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T99640 | 42986-43007 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T29293 | 42988-42993 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T82586 | 43013-43021 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T44634 | 43065-43071 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T38253 | 43076-43082 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T59769 | 43097-43103 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T51490 | 43104-43109 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T70758 | 43110-43116 | Chemical | denotes | ethoxy | http://purl.obolibrary.org/obo/CHEBI_42241 |
| T748 | 43146-43149 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T35101 | 43180-43183 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T750 | 43184-43190 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T56159 | 43204-43220 | Chemical | denotes | 9H-purin-6-amine | http://purl.obolibrary.org/obo/CHEBI_16708 |
| T40430 | 43215-43220 | Chemical | denotes | amine | http://purl.obolibrary.org/obo/CHEBI_32952 |
| T54842 | 43231-43239 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T87374 | 43288-43291 | Chemical | denotes | DCE | http://purl.obolibrary.org/obo/CHEBI_27789 |
| T756 | 43313-43321 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T74109 | 43327-43333 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T5740 | 43396-43399 | Chemical | denotes | DCE | http://purl.obolibrary.org/obo/CHEBI_27789 |
| T759 | 43413-43424 | Chemical | denotes | acetic acid | http://purl.obolibrary.org/obo/CHEBI_15366 |
| T71199 | 43420-43424 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T32586 | 43495-43500 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T94488 | 43502-43508 | Chemical | denotes | sodium | http://purl.obolibrary.org/obo/CHEBI_26708 |
| T52531 | 43608-43616 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T68791 | 43634-43637 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T58335 | 43680-43686 | Chemical | denotes | NaHCO3 | http://purl.obolibrary.org/obo/CHEBI_32139 |
| T85038 | 43725-43728 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T7488 | 43818-43824 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T90420 | 43913-43919 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T12080 | 43946-43950 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T47925 | 43954-43957 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T16758 | 44002-44004 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T56935 | 44011-44015 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T65073 | 44016-44019 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T92650 | 44027-44029 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T24482 | 44044-44049 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T46322 | 44062-44064 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T60945 | 44076-44078 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T82601 | 44090-44092 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T95044 | 44189-44191 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T91404 | 44215-44217 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T68720 | 44254-44256 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T98770 | 44293-44295 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T97976 | 44319-44321 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T70613 | 44358-44360 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T67635 | 44384-44386 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T41136 | 44423-44425 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T38412 | 44463-44465 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T26872 | 44501-44503 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T56080 | 44642-44647 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T79901 | 45026-45047 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T55478 | 45028-45033 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T95880 | 45053-45061 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T86399 | 45105-45111 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T62602 | 45129-45135 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T93521 | 45136-45141 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T84344 | 45142-45148 | Chemical | denotes | ethoxy | http://purl.obolibrary.org/obo/CHEBI_42241 |
| T64034 | 45178-45181 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T27420 | 45212-45215 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T75099 | 45216-45222 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T15092 | 45236-45252 | Chemical | denotes | 9H-purin-6-amine | http://purl.obolibrary.org/obo/CHEBI_16708 |
| T80344 | 45247-45252 | Chemical | denotes | amine | http://purl.obolibrary.org/obo/CHEBI_32952 |
| T44833 | 45263-45271 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T58625 | 45320-45323 | Chemical | denotes | DCE | http://purl.obolibrary.org/obo/CHEBI_27789 |
| T43549 | 45341-45361 | Chemical | denotes | 4-chlorobenzaldehyde | http://purl.obolibrary.org/obo/CHEBI_28105 |
| T25852 | 45403-45406 | Chemical | denotes | DCE | http://purl.obolibrary.org/obo/CHEBI_27789 |
| T810 | 45418-45429 | Chemical | denotes | acetic acid | http://purl.obolibrary.org/obo/CHEBI_15366 |
| T10046 | 45425-45429 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T48049 | 45500-45505 | Chemical | denotes | argon | http://purl.obolibrary.org/obo/CHEBI_49475 |
| T71134 | 45507-45513 | Chemical | denotes | sodium | http://purl.obolibrary.org/obo/CHEBI_26708 |
| T97988 | 45613-45621 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T71462 | 45639-45642 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T34804 | 45685-45691 | Chemical | denotes | NaHCO3 | http://purl.obolibrary.org/obo/CHEBI_32139 |
| T68978 | 45730-45733 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T83602 | 45823-45829 | Chemical | denotes | Na2SO4 | http://purl.obolibrary.org/obo/CHEBI_32149 |
| T96745 | 45918-45924 | Chemical | denotes | silica | http://purl.obolibrary.org/obo/CHEBI_30563 |
| T87703 | 45951-45955 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T12735 | 45959-45962 | Chemical | denotes | DCM | http://purl.obolibrary.org/obo/CHEBI_15767 |
| T3817 | 46018-46020 | Chemical | denotes | Rf | http://purl.obolibrary.org/obo/CHEBI_33346 |
| T45120 | 46027-46031 | Chemical | denotes | MeOH | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T77370 | 46046-46048 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T19055 | 46063-46068 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T59650 | 46081-46083 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T38510 | 46095-46097 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T1609 | 46109-46111 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T45876 | 46123-46125 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T41693 | 46168-46170 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T29338 | 46194-46196 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T74783 | 46252-46254 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T30652 | 46291-46293 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T46105 | 46317-46319 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T46041 | 46356-46358 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T71804 | 46382-46384 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T71447 | 46421-46423 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T43485 | 46461-46463 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T35540 | 46598-46603 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
| T44785 | 46953-46974 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T6211 | 46955-46960 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T33920 | 47001-47007 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T844 | 47027-47048 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T11852 | 47029-47034 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T93810 | 47052-47059 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T29324 | 47063-47076 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T23641 | 47089-47092 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T36442 | 47093-47098 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T851 | 47102-47115 | Chemical | denotes | chlorobenzene | http://purl.obolibrary.org/obo/CHEBI_28097 |
| T32317 | 47118-47129 | Chemical | denotes | sulfonamide | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T99392 | 47218-47230 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T60630 | 47240-47246 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T42652 | 47379-47381 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T51810 | 47396-47400 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T67802 | 47417-47419 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T26836 | 47431-47433 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T14542 | 47446-47448 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T27467 | 47461-47463 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T92762 | 47561-47563 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T62259 | 47587-47589 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T32334 | 47613-47615 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T39588 | 47653-47655 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T30269 | 47679-47681 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T23594 | 47705-47707 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T83151 | 47731-47733 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T50531 | 47757-47759 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T12467 | 47776-47778 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T40390 | 47802-47804 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T61207 | 47895-47897 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T42580 | 47918-47922 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T86710 | 48196-48217 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T27946 | 48198-48203 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T88225 | 48239-48260 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T59442 | 48241-48246 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T63219 | 48264-48271 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T81617 | 48275-48288 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T879 | 48301-48304 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T43726 | 48305-48310 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T90371 | 48315-48321 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T8173 | 48336-48342 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T14707 | 48343-48348 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T886 | 48349-48355 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T7921 | 48356-48363 | Chemical | denotes | oxolane | http://purl.obolibrary.org/obo/CHEBI_26911 |
| T64135 | 48368-48372 | Chemical | denotes | diol | http://purl.obolibrary.org/obo/CHEBI_23824 |
| T33619 | 48461-48473 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T65501 | 48483-48489 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T98605 | 48622-48624 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T15635 | 48639-48643 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T86380 | 48660-48662 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T23466 | 48674-48676 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T27783 | 48688-48690 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T5803 | 48702-48704 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T88932 | 48728-48730 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T47259 | 48754-48756 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T12853 | 48793-48795 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T31063 | 48855-48857 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T68349 | 48881-48883 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T97689 | 48918-48920 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T19922 | 48936-48938 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T74221 | 48962-48964 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T15952 | 49001-49003 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T45027 | 49027-49029 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T58681 | 49053-49055 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T91299 | 49150-49152 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T20981 | 49190-49192 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T94908 | 49232-49236 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T2601 | 49527-49548 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T99463 | 49529-49534 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T63682 | 49570-49591 | Chemical | denotes | 6-amino-9H-purin-9-yl | http://purl.obolibrary.org/obo/CHEBI_30756 |
| T83584 | 49572-49577 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T57305 | 49595-49602 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T917 | 49606-49619 | Chemical | denotes | hydroxymethyl | http://purl.obolibrary.org/obo/CHEBI_24712 |
| T918 | 49632-49635 | Chemical | denotes | oxy | http://purl.obolibrary.org/obo/CHEBI_29354 |
| T54499 | 49636-49641 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T82659 | 49659-49665 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T69918 | 49666-49671 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T47565 | 49672-49678 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T23603 | 49679-49686 | Chemical | denotes | oxolane | http://purl.obolibrary.org/obo/CHEBI_26911 |
| T41132 | 49691-49695 | Chemical | denotes | diol | http://purl.obolibrary.org/obo/CHEBI_23824 |
| T66816 | 49784-49796 | Chemical | denotes | acetonitrile | http://purl.obolibrary.org/obo/CHEBI_38472 |
| T72613 | 49806-49812 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
| T80950 | 49945-49947 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T931 | 49962-49966 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T50590 | 49983-49985 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T933 | 49997-49999 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T70854 | 50011-50013 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T90888 | 50025-50027 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T90836 | 50125-50127 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T44310 | 50151-50153 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T48190 | 50196-50198 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T98950 | 50222-50224 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T940 | 50248-50250 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T84390 | 50287-50289 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T37547 | 50326-50328 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T943 | 50352-50354 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T944 | 50449-50451 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T945 | 50489-50491 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T946 | 50538-50542 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T947 | 50852-50860 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T77784 | 50981-50990 | Chemical | denotes | histidine | http://purl.obolibrary.org/obo/CHEBI_27570 |
| T949 | 51021-51029 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T950 | 51312-51318 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T952 | 51329-51332 | Chemical | denotes | SAM | http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040 |
| T954 | 51488-51495 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T955 | 51503-51507 | Chemical | denotes | Tris | http://purl.obolibrary.org/obo/CHEBI_9754 |
| T956 | 51508-51511 | Chemical | denotes | HCl | http://purl.obolibrary.org/obo/CHEBI_17883 |
| T957 | 51527-51530 | Chemical | denotes | DTT | http://purl.obolibrary.org/obo/CHEBI_18320 |
| T958 | 51537-51542 | Chemical | denotes | MgCl2 | http://purl.obolibrary.org/obo/CHEBI_6636 |
| T959 | 51549-51552 | Chemical | denotes | SAM | http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040 |
| T961 | 51567-51570 | Chemical | denotes | SAM | http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040 |
| T963 | 51810-51814 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T964 | 51825-51829 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T965 | 51872-51875 | Chemical | denotes | SAM | http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040 |
| T967 | 51960-51964 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T968 | 52049-52054 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T969 | 52103-52107 | Chemical | denotes | DEAE | http://purl.obolibrary.org/obo/CHEBI_52153 |
| T970 | 52236-52252 | Chemical | denotes | ammonium formate | http://purl.obolibrary.org/obo/CHEBI_63050 |
| T971 | 52236-52244 | Chemical | denotes | ammonium | http://purl.obolibrary.org/obo/CHEBI_28938 |
| T972 | 52245-52252 | Chemical | denotes | formate | http://purl.obolibrary.org/obo/CHEBI_15740|http://purl.obolibrary.org/obo/CHEBI_52343 |
| T974 | 52272-52277 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T975 | 52292-52299 | Chemical | denotes | ethanol | http://purl.obolibrary.org/obo/CHEBI_16236 |
| T976 | 52365-52371 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T978 | 52471-52478 | Chemical | denotes | Counter | http://purl.obolibrary.org/obo/CHEBI_38960 |
| T979 | 52835-52842 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T980 | 52858-52864 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T981 | 53019-53026 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T982 | 53054-53059 | Chemical | denotes | HEPES | http://purl.obolibrary.org/obo/CHEBI_46756 |
| T983 | 53077-53081 | Chemical | denotes | NaCl | http://purl.obolibrary.org/obo/CHEBI_26710 |
| T984 | 53099-53102 | Chemical | denotes | dye | http://purl.obolibrary.org/obo/CHEBI_37958 |
| T985 | 53137-53144 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T986 | 53192-53196 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T987 | 53200-53205 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T988 | 53207-53210 | Chemical | denotes | SAM | http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040 |
| T990 | 53232-53239 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T991 | 53297-53300 | Chemical | denotes | dye | http://purl.obolibrary.org/obo/CHEBI_37958 |
| T992 | 53547-53551 | Chemical | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262 |
| T993 | 53747-53749 | Chemical | denotes | KD | http://purl.obolibrary.org/obo/CHEBI_73601 |
| T994 | 54008-54010 | Chemical | denotes | La | http://purl.obolibrary.org/obo/CHEBI_33336 |
| T995 | 54208-54214 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T996 | 54215-54218 | Chemical | denotes | SAM | http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040 |
| T998 | 54223-54227 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T999 | 54265-54272 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1000 | 54303-54309 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T1001 | 54386-54393 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1002 | 54398-54404 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T1003 | 54788-54791 | Chemical | denotes | SAM | http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T3 | 1771-1774 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T4 | 2164-2167 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T5 | 3239-3242 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T6 | 3704-3707 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T7 | 5078-5081 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T8 | 5178-5181 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T9 | 5400-5403 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T10 | 5481-5484 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T11 | 6484-6487 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T12 | 8326-8329 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T13 | 8401-8404 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T14 | 8647-8650 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T15 | 8746-8749 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T16 | 8967-8970 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T17 | 9029-9032 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T18 | 15044-15047 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T19 | 15487-15490 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T20 | 16861-16864 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T21 | 18253-18256 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T22 | 26149-26152 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T23 | 27147-27150 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T24 | 28586-28589 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T25 | 30734-30737 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T26 | 32102-32105 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T27 | 33393-33396 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T28 | 34870-34873 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T29 | 41351-41354 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T30 | 41631-41634 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T31 | 41730-41733 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T32 | 41959-41962 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T33 | 43634-43637 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T34 | 43725-43728 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T35 | 43954-43957 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T36 | 44016-44019 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T37 | 45639-45642 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T38 | 45730-45733 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
| T39 | 45959-45962 | Phenotype | denotes | DCM | http://purl.obolibrary.org/obo/HP_0001644 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T45 | 1198-1209 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
| T46 | 1244-1253 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T47 | 2735-2744 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T48 | 6284-6293 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T49 | 6331-6340 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T50 | 14527-14536 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T51 | 52372-52391 | http://purl.obolibrary.org/obo/GO_0030533 | denotes | transfer to the RNA |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32563813-17259217-29105596 | 51111-51113 | 17259217 | denotes | 33 |
| 32563813-17853878-29105597 | 52981-52983 | 17853878 | denotes | 34 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T244 | 0-23 | Sentence | denotes | 4 Experimental section |
| T245 | 25-39 | Sentence | denotes | 4.1 Chemistry |
| T246 | 41-66 | Sentence | denotes | 4.1.1 General procedures |
| T247 | 67-181 | Sentence | denotes | All dry solvents and reagents were purchased from commercial suppliers and were used without further purification. |
| T248 | 182-222 | Sentence | denotes | DIEA was distilled over calcium hydride. |
| T249 | 223-305 | Sentence | denotes | Thin-layer chromatography (TLC) analyses were carried out on silica plate 60 F254. |
| T250 | 306-425 | Sentence | denotes | Purifications by column chromatography were performed using Biotage Isolera 1 system with FlashPure cartridges (Buchi). |
| T251 | 426-509 | Sentence | denotes | NMR experiments were recorded on Bruker 400, 500 or 600 MHz spectrometers at 20 °C. |
| T252 | 510-624 | Sentence | denotes | HRMS analyses were obtained with electrospray ionization (ESI) in positive mode on a Q-TOF Micromass spectrometer. |
| T253 | 625-813 | Sentence | denotes | Analytical HPLC was performed on a UHPLC Thermoscientific Ultimate 3000 system equipped with a LPG-3400RS pump, a DAD 3000 detector and an WPS-3000TBRS Autosampler, Column Oven TCC-3000SD. |
| T254 | 814-932 | Sentence | denotes | Dinucleosides 1–16 were analyzed by RP-HPLC on a Column Nucleodur C18 ec 100-3, 4.6 × 75 mm (Macherey Nagel) at 30 °C. |
| T255 | 933-978 | Sentence | denotes | The following HPLC solvent systems were used: |
| T256 | 979-1055 | Sentence | denotes | 1% CH3CN in 12.5 mM TEAAc (buffer A), 80% CH3CN in 12.5 mM TEEAc (buffer B). |
| T257 | 1056-1079 | Sentence | denotes | Flow rate was 1 mL/min. |
| T258 | 1080-1117 | Sentence | denotes | UV detection was performed at 260 nm. |
| T259 | 1118-1210 | Sentence | denotes | Lyophilized compounds 1–16 were stored at −20 °C for several months without any degradation. |
| T260 | 1212-1284 | Sentence | denotes | 4.1.2 General method A for the synthesis of compounds 18, 26, 27 and 29 |
| T261 | 1285-1365 | Sentence | denotes | To a solution of 5′-amino-2′,3′-isopropylidene adenosine in anhydrous DMF (conc. |
| T262 | 1366-1467 | Sentence | denotes | 0.2 M) was added Et3N (2.00 eq) and the corresponding nitrobenzenesufonyl chloride (1.50 eq) at 0 °C. |
| T263 | 1468-1579 | Sentence | denotes | The reaction mixture was stirred for 4 h at room temperature under argon then was diluted with AcOEt and brine. |
| T264 | 1580-1729 | Sentence | denotes | The aqueous layer was extracted with AcOEt and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. |
| T265 | 1730-1823 | Sentence | denotes | The precipitate was washed with Et2O and DCM to give the desired compound as a colored solid. |
| T266 | 1825-1967 | Sentence | denotes | 4.1.3 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-4-nitrobenzene-1-sulfonamide (18) |
| T267 | 1968-2144 | Sentence | denotes | Following method A with 5′-amino-2′,3′-isopropylidene adenosine (2.21 g, 7.22 mmol, 1.00 eq) and 4-nitrobenzenesufonyl chloride, 18 (2.64 g, 74%) was obtained as a beige solid. |
| T268 | 2145-2169 | Sentence | denotes | Rf 0.50 (8:92 MeOH/DCM). |
| T269 | 2170-2486 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.55 (t, J = 5.8 Hz, 1H), 8.33–8.27 (m, 2H), 8.26 (s, 1H), 8.13 (s, 1H), 7.96–7.88 (m, 2H), 7.37 (br. s, 2H), 6.09 (d, J = 2.8 Hz, 1H), 5.32 (dd, J = 6.3 Hz, 2.9 Hz, 1H), 4.89 (dd, J = 6.3 Hz, 3.0 Hz, 1H), 4.16 (td, J = 5.9 Hz, 3.0 Hz, 1H), 3.24–3.10 (m, 2H), 1.50 (s, 3H), 1.27 (s, 3H). |
| T270 | 2487-2628 | Sentence | denotes | 13C NMR (600 MHz, DMSO‑d 6) δ 156.3, 152.7, 149.5, 148.4, 146.0, 140.2, 128.0, 124.5, 119.3, 113.6, 89.4, 84.4, 83.0, 81.6, 44.6, 27.0, 25.2. |
| T271 | 2629-2675 | Sentence | denotes | HRMS (ESI+): m/z calcd for C19H22N7O7S [M+H]+: |
| T272 | 2676-2701 | Sentence | denotes | 492.1301, Found 492.1311. |
| T273 | 2703-2767 | Sentence | denotes | 4.1.4 General method B for the synthesis of compounds 19, 30-33 |
| T274 | 2768-2820 | Sentence | denotes | To a solution of 18 or 26–29 in anhydrous DMF (conc. |
| T275 | 2821-2899 | Sentence | denotes | 0.13 M) was successively added 17 (1.10 eq), KI (0.30 eq) and K2CO3 (3.00 eq). |
| T276 | 2900-2990 | Sentence | denotes | After stirring for 24 h at 50 °C under argon, the reaction was diluted in AcOEt and water. |
| T277 | 2991-3140 | Sentence | denotes | The aqueous layer was extracted with AcOEt and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. |
| T278 | 3141-3290 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–8% MeOH in DCM) to give the desired compound as colored solid. |
| T279 | 3292-3571 | Sentence | denotes | 4.1.5 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)-4-nitrobenzene-1-sulfonamide (19) |
| T280 | 3572-3683 | Sentence | denotes | Following method B using 18 (290 mg, 0.59 mmol, 1.00 eq), 19 (450 mg, 74%) was obtained as a pale yellow solid. |
| T281 | 3684-3709 | Sentence | denotes | Rf 0.60 (10:90 MeOH/DCM). |
| T282 | 3710-4230 | Sentence | denotes | 1H NMR (600 MHz, CDCl3) δ 8.30 (2s, 2H), 8.14 (s, 1H), 8.03–7.98 (m, 2H), 7.74 (s, 1H), 7.70–7.66 (m, 2H), 6.11–5.93 (m, 5H), 5.89 (d, J = 1.9 Hz, 1H), 5.35 (dd, J = 6.4 Hz, J = 1.9 Hz, 1H), 5.04 (dd, J = 6.4 Hz, J = 3.8 Hz, 1H), 4.51 (dd, J = 6.1 Hz, J = 4.6 Hz, 1H), 4.43 (dt, J = 8.5 Hz, J = 4.2 Hz, 1H), 4.22 (dd, J = 4.7 Hz, J = 3.2 Hz, 1H), 4.05 (dt, J = 5.9 Hz, J = 3.0 Hz, 1H), 3.99 (dd, J = 11.5 Hz, J = 3.5 Hz, 1H), 3.85–3.41 (m, 7H), 1.57 (s, 3H), 1.35 (s, 3H), 0.92 (s, 9H), 0.91 (s, 9H), 0.14–0.04 (m, 12H). |
| T283 | 4231-4494 | Sentence | denotes | 13C NMR (150 MHz, CDCl3) δ 155.8, 155.5, 153.2, 153.0, 149.7, 149.5, 148.9, 145.4, 140.2, 139.5, 128.4, 123.8, 120.5, 120.2, 114.7, 90.7, 87.3, 85.0, 84.5, 84.2, 82.8, 82.6, 69.7, 69.6, 61.5, 50.7, 47.7, 27.3, 26.2, 25.9, 25.4, 18.6, 18.2, −4.4, −4.7, −5.2, −5.3. |
| T284 | 4495-4546 | Sentence | denotes | HRMS (ESI+): m/z calcd for C43H65N12O11SSi2 [M+H]+: |
| T285 | 4547-4564 | Sentence | denotes | 1013.4155, found: |
| T286 | 4565-4575 | Sentence | denotes | 1013.4155. |
| T287 | 4577-4821 | Sentence | denotes | 4.1.6 9-[(2R,5R)-3-[2-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}amino)ethoxy]-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-9H-purin-6-amine (20) |
| T288 | 4822-4983 | Sentence | denotes | To a solution of 19 (210 mg, 0.20 mmol, 1.00 eq) in anhydrous DMF (10 mL) was added K2CO3 (85 mg, 0.61 mmol, 3.00 eq) and thiophenol (11 μL, 1.14 mmol, 5.70 eq). |
| T289 | 4984-5140 | Sentence | denotes | After stirring for 2 h at room temperature under argon, the reaction mixture was diluted with DCM (20 mL) and washed with 1 M aqueous NaOH solution (10 mL). |
| T290 | 5141-5300 | Sentence | denotes | The aqueous layer was extracted with DCM (3 × 20 mL) and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. |
| T291 | 5301-5461 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–15% MeOH in DCM) as the eluent to give 20 (129 mg, 76%) as a white solid. |
| T292 | 5462-5486 | Sentence | denotes | Rf 0.31 (8:92 MeOH/DCM). |
| T293 | 5487-5942 | Sentence | denotes | 1H NMR (500 MHz, CDCl3) δ 8.32 (s, 1H), 8.31 (s, 1H), 8.17 (s, 1H), 7.93 (s, 1H), 6.17–6.06 (m, 5H), 6.03 (d, J = 2.9 Hz, 1H), 5.39 (dd, J = 6.5 Hz, J = 3.0 Hz, 1H), 4.99–4.92 (m, 1H), 4.51–4.45 (m, 1H), 4.33–4.25 (m, 2H), 4.08 (dt, J = 5.6 Hz, J = 3.2 Hz, 1H), 3.98 (dd, J = 11.5 Hz, J = 3.6 Hz, 1H), 3.75 (dd, J = 11.6 Hz, J = 2.8 Hz, 1H), 3.71–3.63 (m, 2H), 2.95–2.69 (m, 4H), 1.61 (s, 3H), 1.37 (s, 3H), 0.92 (s, 9H), 0.88 (s, 9H), 0.13–0.04 (m, 12H). |
| T294 | 5943-6173 | Sentence | denotes | 13C NMR (125 MHz, CDCl3) δ 155.8, 155.7, 153.3, 153.1, 149.7, 149.6, 139.8, 139.4, 120.5, 120.3, 114.8, 90.7, 87.2, 85.8, 85.1, 83.9, 82.6, 82.4, 70.3, 70.13, 62.0, 51.5, 49.5, 27.4, 26.2, 25.8, 18.6, 18.2, −4.5, −4.8, −5.2, −5.3. |
| T295 | 6174-6223 | Sentence | denotes | HRMS (ESI+): m/z calcd for C37H62N11O7Si2 [M+H]+: |
| T296 | 6224-6240 | Sentence | denotes | 828.4372, found: |
| T297 | 6241-6250 | Sentence | denotes | 828.4371. |
| T298 | 6252-6326 | Sentence | denotes | 4.1.7 General method C for the synthesis of compounds 1, 3, 5–7, 9, 10-16 |
| T299 | 6327-6415 | Sentence | denotes | The synthesis intermediate was treated at room temperature with TFA in water (8/2, conc. |
| T300 | 6416-6424 | Sentence | denotes | 0.14 M). |
| T301 | 6425-6583 | Sentence | denotes | After stirring for 3–6 h until completion of reaction (TLC DCM/MeOH), solvents were removed and the residue was coevaporated three times with 7 M NH3 in MeOH. |
| T302 | 6584-6762 | Sentence | denotes | The residue was purified by flash column chromatography on a reversed-phase silica gel column C18 (4 g, 40 μm) with a linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7. |
| T303 | 6763-6904 | Sentence | denotes | The fractions containing the pure compound were pooled, concentrated and lyophilized with water/dioxane to give desired compound as a powder. |
| T304 | 6906-7072 | Sentence | denotes | 4.1.8 (2R,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)amino]methyl}oxolane-3,4-diol (1) |
| T305 | 7073-7319 | Sentence | denotes | Following method C with 20 (117 mg, 0.14 mmol, 1.00 eq) and a 0–25% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 1 (60 mg, 76%) was obtained as a white powder with 99% purity determined by HPLC analysis at 260 nm. |
| T306 | 7320-7703 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.38 (s, 1H), 8.34 (s, 1H), 8.15 (s, 1H), 8.14 (s, 1H), 7.36 (br.s, 2H), 7.29 (br. s, 2H), 5.97 (d, J = 6.4 Hz, 1H), 5.85 (d, J = 5.9 Hz, 1H), 5.58–4.98 (m, 4H), 4.70–4.63 (m, 1H), 4.52 (dd, J = 6.4 Hz, J = 4.7 Hz, 1H), 4.33 (dd, J = 4.7 Hz, J = 2.6 Hz, 1H), 4.12 (dd, J = 5.2 Hz, J = 3.8 Hz, 1H), 4.02–3.93 (m, 2H), 3.70–3.48 (m, 4H), 2.86–2.58 (m, 4H). |
| T307 | 7704-7874 | Sentence | denotes | 13C NMR (150 MHz, DMSO‑d 6) δ 156.2, 156.1, 152.6, 152.5, 149.4, 149.0, 140.1, 139.9, 119.4, 119.3, 87.6, 86.3 (2C), 83.7, 81.5, 72.8, 71.5, 69.5, 69.1, 61.7, 51.2, 49.0. |
| T308 | 7875-7921 | Sentence | denotes | HRMS (ESI+): m/z calcd for C22H30N11O7 [M+H]+: |
| T309 | 7922-7939 | Sentence | denotes | 560.23242, found: |
| T310 | 7940-7950 | Sentence | denotes | 560.23188. |
| T311 | 7952-8263 | Sentence | denotes | 4.1.9 Methyl (2S)-4-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)amino)-2-{bis[(tert-butoxy)carbonyl]amino}butanoate (22) |
| T312 | 8264-8456 | Sentence | denotes | To a solution of 20 (250 mg, 0.30 mmol, 1.00 eq) in anhydrous DCM (9 mL) was added aldehyde 21 (120 mg, 0.36 mmol, 1.20 eq) in anhydrous DCM (9 mL) and acetic acid (20 μL, 0.36 mmol, 1.20 eq). |
| T313 | 8457-8582 | Sentence | denotes | After stirring for 20 min at room temperature under argon, sodium triacetoxyborohydride (96 mg, 0.45 mmol, 1.5 eq) was added. |
| T314 | 8583-8708 | Sentence | denotes | After stirring for 2.5 h, the reaction mixture was diluted with DCM (30 mL) and washed with saturated aqueous NaHCO3 (30 mL). |
| T315 | 8709-8868 | Sentence | denotes | The aqueous layer was extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. |
| T316 | 8869-9014 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–8% MeOH in DCM) to give 22 (321 mg, 93%) as a white solid. |
| T317 | 9015-9039 | Sentence | denotes | Rf 0.71 (MeOH/DCM 5:95). |
| T318 | 9040-9587 | Sentence | denotes | 1H NMR (600 MHz, CDCl3) δ 8.33 (s, 1H), 8.30 (s, 1H), 8.17 (s, 1H), 7.93 (s, 1H), 6.09 (d, J = 3.3 Hz, 1H), 6.01 (d, J = 2.4 Hz, 1H), 5.97 (m, 4H), 5.42 (dd, J = 6.5 Hz, J = 2.4 Hz, 1H), 4.93–4.86 (m, 2H), 4.54–4.49 (m, 1H), 4.33 (td, J = 6.8 Hz, J = 3.3 Hz, 1H), 4.29–4.24 (m, 1H), 4.08 (dt, J = 6.2 Hz, J = 3.2 Hz, 1H), 3.99 (dd, J = 11.5 Hz, J = 3.7 Hz, 1H), 3.78–3.63 (m, 6H), 2.84–2.74 (m, 3H), 2.71–2.51 (m, 3H), 2.33–2.23 (m, 1H), 1.91–1.82 (m, 1H), 1.58 (s, 3H), 1.46 (s, 18H), 1.36 (s, 3H), 0.91 (s, 9H), 0.90 (s, 9H), 0.10–0.05 (m, 12H). |
| T319 | 9588-9874 | Sentence | denotes | 13C NMR (125 MHz, CDCl3) δ 171.6, 155.8, 155.7, 153.3, 153.2, 152.3, 149.7, 149.5, 140.1, 139.8, 120.5, 120.4, 114.5, 91.1, 87.4, 85.45, 84.8, 84.1, 83.3, 83.3, 82.5, 69.9, 69.1, 61.9, 56.3, 56.3, 53.7, 52.4, 52.1, 28.1, 28.1, 27.3, 26.2, 26.0, 25.6, 18.7, 18.3, −4.3, −4.6, −5.2, −5.2. |
| T320 | 9875-9925 | Sentence | denotes | HRMS (ESI+): m/z calcd for C52H87N12O13Si2 [M+H]+: |
| T321 | 9926-9943 | Sentence | denotes | 1143.6049, found: |
| T322 | 9944-9954 | Sentence | denotes | 1143.6043. |
| T323 | 9956-10159 | Sentence | denotes | 4.1.10 (2S)-4-({[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)amino)-2-azaniumylbutanoate (2) |
| T324 | 10160-10268 | Sentence | denotes | Compound 22 (86 mg, 75.3 μmol, 1.00 eq) was treated at room temperature with TFA (830 μL) in water (210 μL). |
| T325 | 10269-10328 | Sentence | denotes | After stirring for 3 h, solvents were removed under vacuum. |
| T326 | 10329-10420 | Sentence | denotes | The residue was dissolved in water (0.5 mL) and 2 M aqueous LiOH solution (4 mL) was added. |
| T327 | 10421-10521 | Sentence | denotes | After stirring at 0 °C for 30 min, pH ≈ 3 or 4 was adjusted by addition of 1 M aqueous HCl solution. |
| T328 | 10522-10747 | Sentence | denotes | The solvent was removed under vacuum and the residue was purified by flash column chromatography on a reversed-phase silica gel column C18 (4 g, 40 μm) with a 0–15% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7. |
| T329 | 10748-10939 | Sentence | denotes | The fractions containing the pure compound were pooled, concentrated and lyophilized with water to give 2 (16 mg, 32%) as a white powder with 99% purity determined by HPLC analysis at 260 nm. |
| T330 | 10940-11374 | Sentence | denotes | 1H NMR (600 MHz, D2O) δ 8.11 (s, 1H), 8.05 (s, 1H), 7.98 (s, 1H), 7.86 (s, 1H), 5.89 (d, J = 2.5 Hz, 1H), 5.77 (d, J = 3.3 Hz, 1H), 4.51–4.47 (m, 2H), 4.36 (dd, J = 5.1 Hz, J = 3.4 Hz, 1H), 4.34–4.29 (m, 1H), 4.14–4.08 (m, 2H), 3.97 (td, J = 10.6 Hz, J = 2.4 Hz, 1H), 3.89–3.80 (m, 3H), 3.71 (dd, J = 13.0, J = 3.4 Hz, 1H), 3.15–3.04 (m, 2H), 3.03–2.81 (m, 2H), 2.76 (d, J = 14.2 Hz, 1H), 2.58 (d, J = 13.8 Hz, 1H), 2.14–1.99 (m, 2H). |
| T331 | 11375-11563 | Sentence | denotes | 13C NMR (150 MHz, D2O) δ 174.5, 154.9 (2C) 152.5, 152.2, 147.7, 147.5, 139.3, 138.5, 118.5, 118.2, 89.0, 86.8, 84.8, 81.7, 80.0, 73.9, 71.1, 68.9, 67.7, 60.3, 56.2, 55.3, 53.8, 52.5, 26.1. |
| T332 | 11564-11610 | Sentence | denotes | HRMS (ESI+): m/z calcd for C26H37N12O9 [M+H]+: |
| T333 | 11611-11627 | Sentence | denotes | 661.2806, found: |
| T334 | 11628-11637 | Sentence | denotes | 661.2811. |
| T335 | 11639-11845 | Sentence | denotes | 4.1.11 Methyl (2S)-2-amino-4-({[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)amino)butanoate (3) |
| T336 | 11846-12092 | Sentence | denotes | Following method C with 22 (140 mg, 0.12 mmol, 1.00 eq) and a 0–30% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 3 (28 mg, 35%) was obtained as a white powder with 98% purity determined by HPLC analysis at 260 nm. |
| T337 | 12093-12628 | Sentence | denotes | 1H NMR (600 MHz, D2O) δ 8.08 (s, 1H), 8.05 (s, 1H), 7.98 (s, 1H), 7.84 (s, 1H), 5.89 (d, J = 2.5 Hz, 1H), 5.75 (d, J = 3.3 Hz, 1H), 4.55–4.50 (m, 1H), 4.47 (dd, J = 5.1 Hz, J = 2.3 Hz, 1H), 4.38 (dd, J = 5.0 Hz, J = 3.2 Hz, 1H), 4.36–4.30 (m, 1H), 4.26 (dd, J = 10.5 Hz, J = 2.8 Hz, 1H), 4.13 (dd, J = 7.9 Hz, J = 5.1 Hz, 1H), 4.07 (dt, J = 6.2 Hz, J = 3.1 Hz, 1H), 4.05–3.86 (m, 2H), 3.84 (s, 3H), 3.82–3.64 (m, 2H), 3.22–3.01 (m, 3H), 2.88 (dt, J = 13.7, J = 3.9, 1H), 2.78 (d, J = 13.9 Hz, 1H), 2.66–2.58 (m, 1H), 2.19–2.02 (m, 2H). |
| T338 | 12629-12818 | Sentence | denotes | 13C NMR (150 MHz, D2O) δ 170.6, 154.9 (2C), 152.5, 152.2, 147.7, 147.4, 139.1, 138.3, 118.5, 118.1, 89.1, 86.8, 84.6, 81.8, 79.6, 73.9, 70.9, 69.1, 60.2, 54.8, 54.1, 53.5, 53.3, 52.3, 25.0. |
| T339 | 12819-12865 | Sentence | denotes | HRMS (ESI+): m/z calcd for C27H39N12O9 [M+H]+: |
| T340 | 12866-12882 | Sentence | denotes | 675.2957, found: |
| T341 | 12883-12892 | Sentence | denotes | 675.2944. |
| T342 | 12894-13094 | Sentence | denotes | 4.1.12 (2S)-2-amino-4-({[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)amino)butanamide (4) |
| T343 | 13095-13245 | Sentence | denotes | Compound 22 (116 mg, 0.10 mmol, 1.00 eq) was treated at room temperature with TFA (1.44 mL) in water (360 μL) and stirred for 3 h at room temperature. |
| T344 | 13246-13329 | Sentence | denotes | The solvents were removed and the residue was treated with 7 M NH3 in MeOH (10 mL). |
| T345 | 13330-13574 | Sentence | denotes | After stirring for 24 h at 30 °C, solvents were removed and the residue was purified by flash column chromatography on a reversed-phase silica gel column C18 (4 g, 40 μm) with a 0–15% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7. |
| T346 | 13575-13766 | Sentence | denotes | The fractions containing the pure compound were pooled, concentrated and lyophilized with water to give 4 (23 mg, 38%) as a white powder with 98% purity determined by HPLC analysis at 260 nm. |
| T347 | 13767-14229 | Sentence | denotes | 1H NMR (600 MHz, D2O) δ 8.12 (s, 1H), 8.08 (s, 1H), 7.99 (s, 1H), 7.90 (s, 1H), 5.90 (d, J = 2.7 Hz, 1H), 5.79 (d, J = 3.5 Hz, 1H), 4.53 (dd, J = 5.2 Hz, J = 2.7 Hz, 1H), 4.52–4.48 (m, 1H), 4.38 (dd, J = 5.0 Hz, J = 3.6 Hz, 1H), 4.35–4.28 (m, 1H), 4.18–4.07 (m, 3H), 3.98 (td, J = 10.7 Hz, J = 2.6 Hz, 1H), 3.88–3.80 (m, 2H), 3.72 (dd, J = 12.9 Hz, J = 3.5 Hz, 1H), 3.16–2.98 (m, 3H), 2.88–2.76 (m, 2H), 2.62 (dt, J = 14.0 Hz, J = 2.7 Hz, 1H), 2.17–1.98 (m, 2H). |
| T348 | 14230-14418 | Sentence | denotes | 13C NMR (150 MHz, D2O) δ 173.0, 155.0 (2C) 152.5, 152.3, 147.8, 147.6, 139.4, 138.7, 118.6, 118.3, 88.9, 86.8, 84.9, 81.8, 79.8, 73.8, 71.1, 69.0, 67.6, 60.4, 55.3, 53.9, 52.6, 52.4, 27.0. |
| T349 | 14419-14465 | Sentence | denotes | HRMS (ESI+): m/z calcd for C26H38N13O8 [M+H]+: |
| T350 | 14466-14482 | Sentence | denotes | 660.2961, found: |
| T351 | 14483-14492 | Sentence | denotes | 660.2966. |
| T352 | 14494-14563 | Sentence | denotes | 4.1.13 General method D for the synthesis of compounds 23, 24 and 25 |
| T353 | 14564-14607 | Sentence | denotes | To a solution of 20 in anhydrous NMP (conc. |
| T354 | 14608-14689 | Sentence | denotes | 0.03 M) was added the corresponding bromide reagent (3.00 eq) and DIEA (3.00 eq). |
| T355 | 14690-14795 | Sentence | denotes | After stirring for 4 h at 110 °C under microwaves, the reaction mixture was diluted with AcOEt and brine. |
| T356 | 14796-14945 | Sentence | denotes | The aqueous layer was extracted with AcOEt and the combined organic extracts were washed with brine, dried over Na2SO4 and concentrated under vacuum. |
| T357 | 14946-15099 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–4% MeOH in DCM) to give the desired compound as a colorless solid. |
| T358 | 15101-15353 | Sentence | denotes | 4.1.14 9-[(2R,5R)-3-[2-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}(butyl)amino)ethoxy]-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-9H-purin-6-amine (23) |
| T359 | 15354-15472 | Sentence | denotes | Following method D with 20 (80 mg, 97 μmol, 1.00 eq) and 1-bromobutane, 23 (40 mg, 47%) was obtained as a white solid. |
| T360 | 15473-15497 | Sentence | denotes | Rf 0.48 (MeOH/DCM 5:95). |
| T361 | 15498-16114 | Sentence | denotes | 1H NMR (600 MHz, CDCl3) δ 8.33 (s, 2H), 8.16 (s, 1H), 7.92 (s, 1H), 6.11 (d, J = 3.8 Hz, 1H), 6.03 (d, J = 2.3 Hz, 1H), 5.77 (br. s, 4H), 5.47 (dd, J = 6.4 Hz, J = 2.2 Hz, 1H), 4.91 (dd, J = 6.4 Hz, J = 3.2 Hz, 1H), 4.51 (t, J = 5.1 Hz, 1H), 4.37–4.24 (m, 2H), 4.09 (dt, J = 5.9 Hz, J = 3.0 Hz, 1H), 3.99 (dd, J = 11.5 Hz, J = 3.7 Hz, 1H), 3.76 (dd, J = 11.5 Hz, J = 2.8 Hz, 1H), 3.70–3.61 (m, 2H), 2.77–2.68 (m, 3H), 2.63 (dd, J = 13.5 Hz, J = 7.0 Hz, 1H), 2.46–2.37 (m, 2H), 1.59 (s, 3H), 1.38 (s, 3H), 1.31–1.22 (m, 2H), 1.22–1.12 (m, 2H), 0.92 (s, 9H), 0.91 (s, 9H), 0.82 (t, J = 7.3 Hz, 3H), 0.10–0.08 (m, 12H). |
| T362 | 16115-16374 | Sentence | denotes | 13C NMR (150 MHz, CDCl3) δ 155.6, 155.5, 153.2, 153.1, 149.8, 149.4, 140.2, 139.7, 120.5, 120.3, 114.4, 91.2, 87.2, 85.8, 84.9, 84.0, 83.4, 82.4, 69.9, 69.3, 62.0, 56.7, 55.1, 53.9, 29.2, 27.2, 26.1, 25.9, 25.5, 20.5, 18.6, 18.2, 14.1, −4.4, −4.6, −5.2, −5.2. |
| T363 | 16375-16424 | Sentence | denotes | HRMS (ESI+): m/z calcd for C46H72N11O7Si2 [M+H]+: |
| T364 | 16425-16441 | Sentence | denotes | 884.4998, found: |
| T365 | 16442-16451 | Sentence | denotes | 884.5002. |
| T366 | 16453-16714 | Sentence | denotes | 4.1.15 9-[(2R,5R)-3-[2-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}(3-phenylpropyl)amino)ethoxy]-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-9H-purin-6-amine (24) |
| T367 | 16715-16846 | Sentence | denotes | Following method D with 20 (120 mg, 0.15 mmol, 1.00 eq) and 1-bromo-3-phenylpropane, 24 (75 mg, 53%) was obtained as a white solid. |
| T368 | 16847-17756 | Sentence | denotes | Rf 0.53 (MeOH/DCM 5:95).1H NMR (600 MHz, CDCl3) δ 8.31 (s, 1H), 8.28 (s, 1H), 8.15 (s, 1H), 7.90 (s, 1H), 7.25–7.08 (m, 5H), 6.11 (d, J = 3.7 Hz, 1H), 6.02 (d, J = 2.4 Hz, 1H), 5.81 (br. s, 4H), 5.46 (dd, J = 6.5 Hz, J = 2.1 Hz, 1H), 4.92 (dd, J = 6.5 Hz, J = 3.2 Hz, 1H), 4.50 (t, J = 5.1 Hz, 1H), 4.33–4.24 (m, 2H), 4.08 (dt, J = 5.9 Hz, J = 3.2 Hz, 1H), 3.98 (dd, J = 11.4 Hz, J = 3.6 Hz, 1H), 3.76 (dd, J = 11.5 Hz, J = 2.8 Hz, 1H), 3.72–3.60 (m, 2H), 2.80–2.70 (m, 3H), 2.64 (dd, J = 13.7 Hz, J = 6.7 Hz, 1H), 2.56–2.43 (m, 4H), 1.69–1.62 (m, 2H), 1.58 (s, 3H), 1.37 (s, 3H), 0.92 (s, 9H), 0.90 (s, 9H), 0.13–0.04 (m, 12H).13C NMR (150 MHz, CDCl3) δ 155.6, 155.5, 153.2, 153.1, 149.7, 149.4, 142.2, 140.2, 139.6, 128.4, 128.4, 125.8, 120.5, 120.3, 114.4, 91.1, 87.2, 85.7, 84.8, 83.9, 83.3, 82.5, 69.8, 69.3, 61.8, 56.7, 54.9, 53.9, 33.5, 28.8, 27.2, 26.1, 25.8, 25.5, 18.6, 18.2, −4.4, −4.6, −5.2, −5.2. |
| T369 | 17757-17806 | Sentence | denotes | HRMS (ESI+): m/z calcd for C46H72N11O7Si2 [M+H]+: |
| T370 | 17807-17823 | Sentence | denotes | 946.5155, found: |
| T371 | 17824-17833 | Sentence | denotes | 946.5149. |
| T372 | 17835-18106 | Sentence | denotes | 4.1.16 Methyl 4-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)amino)butanoate (25) |
| T373 | 18107-18238 | Sentence | denotes | Following method D with 20 (600 mg, 0.73 mmol, 1.00 eq) and methyl-4-bromobutyrate, 25 (390 mg, 58%) was obtained as a white solid. |
| T374 | 18239-18263 | Sentence | denotes | Rf 0.34 (MeOH/DCM 5:95). |
| T375 | 18264-18878 | Sentence | denotes | 1H NMR (600 MHz, CDCl3) δ 8.32 (s, 1H), 8.31 (s, 1H), 8.17 (s, 1H), 7.90 (s, 1H), 6.11 (d, J = 3.6 Hz, 1H), 6.02 (m, 5H), 5.45 (dd, J = 6.5 Hz, J = 2.2 Hz, 1H), 4.91 (dd, J = 6.6 Hz, J = 3.3 Hz, 1H), 4.51 (t, J = 5.3 Hz, 1H), 4.32–4.23 (m, 2H), 4.08 (dt, J = 6.1 Hz, J = 3.2 Hz, 1H), 3.99 (dd, J = 11.5 Hz, J = 3.6 Hz, 1H), 3.76 (dd, J = 11.5 Hz, J = 2.8 Hz, 1H), 3.71–3.60 (m, 5H), 2.77 (dd, J = 13.5 Hz, J = 6.9 Hz, 1H), 2.74–2.69 (m, 2H), 2.64 (dd, J = 13.5 Hz, J = 6.8 Hz, 1H), 2.51–2.44 (m, 2H), 2.32–2.18 (m, 2H), 1.69–1.61 (m, 2H), 1.58 (s, 3H), 1.37 (s, 3H), 0.92 (s, 9H), 0.90 (s, 9H), 0.13–0.04 (m, 12H). |
| T376 | 18879-19145 | Sentence | denotes | 13C NMR (150 MHz, CDCl3) δ 174.0, 155.7, 155.6, 153.2, 153.1, 149.7, 149.4, 140.1, 139.5, 120.5, 120.3, 114.4, 91.1, 87.2, 85.7, 84.8, 83.9, 83.3, 82.5, 69.8, 69.3, 61.9, 56.7, 54.3, 53.7, 51.6, 31.5, 27.2, 26.1, 25.8, 25.5, 22.6, 18.6, 18.2, −4.4, −4.6, −5.2, −5.2. |
| T377 | 19146-19195 | Sentence | denotes | HRMS (ESI+): m/z calcd for C42H70N11O9Si2 [M+H]+: |
| T378 | 19196-19212 | Sentence | denotes | 928.4897, found: |
| T379 | 19213-19222 | Sentence | denotes | 928.4900. |
| T380 | 19224-19398 | Sentence | denotes | 4.1.17 (2R,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)(butyl)amino]methyl}oxolane-3,4-diol (5) |
| T381 | 19399-20188 | Sentence | denotes | Following method C with 23 (40 mg, 0.45 mol, 1.00 eq) and a 0–50% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 5 (20 mg, 72%) was obtained as a white powder with 98% purity determined by HPLC analysis at 260 nm.1H NMR (500 MHz, DMSO‑d 6) δ 8.36 (s, 1H), 8.32 (s, 1H), 8.14 (s, 1H), 8.13 (s, 1H), 7.33 (br. s, 2H), 7.25 (br. s, 2H), 5.97 (d, J = 6.3 Hz, 1H), 5.85 (d, J = 5.2 Hz, 1H), 5.49–5.39 (m, 3H), 5.14 (d, J = 5.3 Hz, 1H), 4.62 (q, J = 5.4 Hz, 1H), 4.52 (dd, J = 6.5, 4.7 Hz, 1H), 4.29 (dd, J = 4.8, 2.8 Hz, 1H), 4.06 (q, J = 4.9 Hz, 1H), 4.00–3.92 (m, 2H), 3.68–3.46 (m, 4H), 2.79 (dd, J = 14.0, 4.6 Hz, 1H), 2.70–2.51 (m, 3H), 2.41–2.30 (m, 2H), 1.22 (q, J = 7.4, 2H), 1.07 (tdd, J = 13.4 Hz, J = 10.5 Hz, J = 6.3 Hz, 2H), 0.73 (t, J = 7.3 Hz, 2H). |
| T382 | 20189-20384 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 156.2, 156.0, 152.6, 152.4, 149.3, 148.9, 139.8, 139.8, 119.3, 119.1, 87.5, 86.3, 86.2, 82.4, 81.2, 72.5, 71.9, 69.2, 67.9, 61.5, 56.1, 54.0, 53.7, 28.3, 19.8, 13.7. |
| T383 | 20385-20431 | Sentence | denotes | HRMS (ESI+): m/z calcd for C26H38N11O7 [M+H]+: |
| T384 | 20432-20457 | Sentence | denotes | 616.2956, Found 616.2955. |
| T385 | 20459-20642 | Sentence | denotes | 4.1.18 (2R,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)(3-phenylpropyl)amino]methyl}oxolane-3,4-diol (6) |
| T386 | 20643-20887 | Sentence | denotes | Following method C with 24 (40 mg, 0.42 μmol, 1.00 eq) and a 0–50% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 6 (8 mg, 28%) was obtained as a white powder with 99% purity determined by HPLC analysis at 260 nm. |
| T387 | 20888-21433 | Sentence | denotes | 1H NMR (500 MHz, DMSO‑d 6) δ 8.36 (s, 1H), 8.32 (s, 1H), 8.14 (s, 1H), 8.13 (s, 1H), 7.33 (br. s, 2H), 7.25 (br. s, 2H), 5.97 (d, J = 6.3 Hz, 1H), 5.85 (d, J = 5.2 Hz, 1H), 5.49–5.39 (m, 3H), 5.14 (d, J = 5.3 Hz, 1H), 4.62 (q, J = 5.4 Hz, 1H), 4.52 (dd, J = 6.5, 4.7 Hz, 1H), 4.29 (dd, J = 4.8, 2.8 Hz, 1H), 4.06 (q, J = 4.9 Hz, 1H), 4.00–3.92 (m, 2H), 3.68–3.46 (m, 4H), 2.79 (dd, J = 14.0, 4.6 Hz, 1H), 2.70–2.51 (m, 3H), 2.41–2.30 (m, 2H), 1.22 (q, J = 7.4, 2H), 1.07 (tdd, J = 13.4 Hz, J = 10.5 Hz, J = 6.3 Hz, 2H), 0.73 (t, J = 7.3 Hz, 2H). |
| T388 | 21434-21629 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 156.1, 156.0, 152.5, 152.4, 149.3, 149.0, 139.8, 139.8, 119.3, 119.2, 87.6, 86.3, 86.2, 82.4, 81.2, 72.5, 71.9, 69.2, 68.0, 62.0, 56.2, 54.0, 53.7, 28.3, 19.8, 13.8. |
| T389 | 21630-21676 | Sentence | denotes | HRMS (ESI+): m/z calcd for C26H38N11O7 [M+H]+: |
| T390 | 21677-21702 | Sentence | denotes | 616.2956, Found 616.2955. |
| T391 | 21704-21897 | Sentence | denotes | 4.1.19 Methyl 4-({[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)amino)butanoate (7) |
| T392 | 21898-22144 | Sentence | denotes | Following method C with 25 (116 mg, 0.13 mmol, 1.00 eq) and a 0–50% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 7 (51 mg, 60%) was obtained as a white powder with 97% purity determined by HPLC analysis at 260 nm. |
| T393 | 22145-22690 | Sentence | denotes | 1H NMR (500 MHz, DMSO‑d 6) δ 8.37 (s, 1H), 8.33 (s, 1H), 8.14 (s, 1H), 8.13 (s, 1H), 7.38 (br. s, 2H), 7.29 (br. s, 2H), 5.97 (d, J = 6.3 Hz, 1H), 5.84 (d, J = 5.3 Hz, 1H), 5.52–5.32 (m, 3H), 5.19 (d, J = 5.3 Hz, 1H), 4.62 (q, J = 5.4 Hz, 1H), 4.49 (dd, J = 6.3, 4.7 Hz, 1H), 4.30 (dd, J = 4.8, 2.8 Hz, 1H), 4.04 (q, J = 4.9 Hz, 1H), 3.99–3.96 (m, 1H), 3.95–3.87 (m, 1H), 3.66 (dt, J = 12.1, 4.1 Hz, 1H), 3.62–3.45 (m, 6H), 2.79 (dd, J = 14.1, 4.6 Hz, 1H), 2.71–2.52 (m, 3H), 2.45–2.28 (m, 2H), 2.14 (td, J = 7.4, 5.9 Hz, 2H), 1.58–1.46 (m, 2H). |
| T394 | 22691-22893 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 173.3, 156.2, 156.1, 152.6, 152.5, 149.4, 148.9, 139.9, 139.8, 119.4, 119.2, 87.6, 86.4, 86.3, 82.4, 81.3, 72.6, 71.9, 69.2, 68.0, 61.6, 56.3, 53.5, 53.4, 51.2, 30.9, 21.8. |
| T395 | 22894-22940 | Sentence | denotes | HRMS (ESI+): m/z calcd for C27H38N11O9 [M+H]+: |
| T396 | 22941-22966 | Sentence | denotes | 660.2854, Found 660.2855. |
| T397 | 22968-23157 | Sentence | denotes | 4.1.20 4-({[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(2-[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)amino)butanoic acid (8) |
| T398 | 23158-23250 | Sentence | denotes | Compound 25 (140 mg, 0.15 mmol, 1.00 eq) was treated with TFA (1.37 mL) and water (0.34 mL). |
| T399 | 23251-23312 | Sentence | denotes | After stirring for 5.5 h, solvents were removed under vacuum. |
| T400 | 23313-23406 | Sentence | denotes | The residue was dissolved in water (0.5 mL) and 2 M LiOH aqueous solution (3.5 mL) was added. |
| T401 | 23407-23509 | Sentence | denotes | After stirring at 0 °C for 30 min, pH was adjusted to ≈3 or 4 by addition of 1 M HCl aqueous solution. |
| T402 | 23510-23733 | Sentence | denotes | Solvents were removed under vacuum and the residue was purified by flash column chromatography on a reversed-phase silica gel column C18 (4 g, 40 μm) with a 0–20% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7. |
| T403 | 23734-23941 | Sentence | denotes | The fractions containing the pure compound were pooled, concentrated and lyophilized with water and 1,4-dioxane to give 8 (35 mg, 36%) as a white powder with 99% purity determined by HPLC analysis at 260 nm. |
| T404 | 23942-24352 | Sentence | denotes | 1H NMR (600 MHz, D2O) δ 8.24 (s, 1H), 8.13 (s, 1H), 8.05 (s, 1H), 8.01 (s, 1H), 5.98 (d, J = 4.3 Hz, 1H), 5.94 (d, J = 4.6 Hz, 1H), 4.68–4.59 (m, 1H), 4.51–4.44 (m, 2H), 4.44–4.38 (m, 1H), 4.38–4.30 (m, 1H), 4.23–4.15 (m, 1H), 4.09–3.95 (m, 2H), 3.91 (dd, J = 12.9, J = 2.7 Hz, 1H), 3.80 (dd, J = 12.9, J = 3.8 Hz, 1H), 3.69–3.33 (m, 4H), 3.20 (m, 2H), 2.29 (td, J = 7.0 Hz, J = 2.7 Hz, 2H), 2.02–1.85 (m, 2H). |
| T405 | 24353-24542 | Sentence | denotes | 13C NMR (150 MHz, D2O) δ 174.5, 154.9 (2C), 152.5, 152.3, 147.7, 147.5, 139.3, 138.5, 118.6, 118.3, 89.0, 86.9, 84.8, 81.8, 80.1, 73.9, 71.1, 69.0, 67.8, 60.3, 56.2, 55.3, 53.8, 52.5, 26.1. |
| T406 | 24543-24589 | Sentence | denotes | HRMS (ESI+): m/z calcd for C26H37N12O9 [M+H]+: |
| T407 | 24590-24606 | Sentence | denotes | 661.2806, found: |
| T408 | 24607-24616 | Sentence | denotes | 661.2811. |
| T409 | 24618-24820 | Sentence | denotes | 4.1.21 N-{[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)-4-nitrobenzene-1-sulfonamide (9) |
| T410 | 24821-25063 | Sentence | denotes | Using method C with 19 (100 mg, 97.4 μmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 9 (25 mg, 34%) was obtained as a white powder with 99% purity determined by HPLC analysis at 260 nm. |
| T411 | 25064-25512 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.32 (s, 1H), 8.29 (s, 1H), 8.22–8.18 (m, 2H), 8.14 (s, 1H), 8.13 (s, 1H), 7.96–7.91 (m, 2H), 7.32 (br. s, 2H), 7.26 (br. s, 2H), 5.89 (d, J = 5.4 Hz, 1H), 5.79 (d, J = 5.6 Hz, 1H), 5.73–5.20 (m, 4H), 4.70 (t, J = 5.4 Hz, 1H), 4.34 (t, J = 5.1 Hz, 1H), 4.30–4.26 (m, 1H), 4.15 (t, J = 4.6 Hz, 1H), 4.09 (dt, J = 8.5 Hz, J = 4.3 Hz, 1H), 3.89 (q, J = 3.6 Hz, 1H), 3.75–3.70 (m, 2H), 3.66–3.63 (m, 1H), 3.60–3.29 (m, 5H). |
| T412 | 25513-25712 | Sentence | denotes | 13C NMR (150 MHz, DMSO‑d 6) δ 156.2, 156.2, 152.8, 152.7, 149.6, 149.3, 149.0, 145.0, 140.2, 139.6, 128.5, 124.3, 119.3, 119.3, 87.9, 86.3, 86.0, 82.9, 81.6, 72.5, 71.4, 70.0, 68.2, 61.2, 50.4, 47.5. |
| T413 | 25713-25761 | Sentence | denotes | HRMS (ESI+): m/z calcd for C28H33N12O11S [M+H]+: |
| T414 | 25762-25787 | Sentence | denotes | 745.2112, Found 745.2104. |
| T415 | 25789-25942 | Sentence | denotes | 4.1.22 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-4-methoxy-2-nitrobenzene-1-sulfonamide (26) |
| T416 | 25943-26129 | Sentence | denotes | Following method A with 5′-amino-2′,3′-isopropylidene adenosine (280 mg, 0.92 mmol, 1.00 eq) and 4-methoxy-2-nitrobenzenesufonyl chloride, 26 (191 mg, 40%) was obtained as a beige solid. |
| T417 | 26130-26154 | Sentence | denotes | Rf 0.59 (8:92 MeOH/DCM). |
| T418 | 26155-26550 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.43 (t, J = 5.8 Hz, 1H), 8.28 (s, 1H), 8.12 (s, 1H), 7.74 (d, J = 8.9 Hz, 1H), 7.51 (d, J = 2.6 Hz, 1H), 7.40 (br. s, 2H), 7.20 (dd, J = 8.9 Hz, J = 2.6 Hz, 1H), 6.11 (d, J = 3.0 Hz, 1H), 5.36 (dd, J = 6.3 Hz, J = 3.0 Hz, 1H), 4.93 (dd, J = 6.4 Hz, J = 2.9 Hz, 1H), 4.23 (td, J = 5.8 Hz, J = 2.9 Hz, 1H), 3.87 (s, 3H), 3.27–3.14 (m, 2H), 1.52 (s, 3H), 1.28 (s, 3H). |
| T419 | 26551-26712 | Sentence | denotes | 13C NMR (150 MHz, DMSO‑d 6) δ 162.5, 156.2, 153.0, 149.0, 148.3, 140.2, 131.3, 123.8, 119.3, 117.2, 113.5, 109.8, 89.5, 84.1, 82.8, 81.5, 56.6, 44.5, 27.0, 25.1. |
| T420 | 26713-26759 | Sentence | denotes | HRMS (ESI+): m/z calcd for C20H24N7O8S [M+H]+: |
| T421 | 26760-26785 | Sentence | denotes | 522.1407, Found 522.1407. |
| T422 | 26787-26940 | Sentence | denotes | 4.1.23 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-2-methoxy-4-nitrobenzene-1-sulfonamide (27) |
| T423 | 26941-27127 | Sentence | denotes | Following method A with 5′-amino-2′,3′-isopropylidene adenosine (280 mg, 0.92 mmol, 1.00 eq) and 2-methoxy-4-nitrobenzenesufonyl chloride, 27 (200 mg, 42%) was obtained as a beige solid. |
| T424 | 27128-27152 | Sentence | denotes | Rf 0.59 (8:92 MeOH/DCM). |
| T425 | 27153-27515 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.30 (t, J = 5.4 Hz, 1H), 8.23 (s, 1H), 8.12 (s, 1H), 7.88–7.82 (m, 2H), 7.77 (dd, J = 8.5 Hz, J = 2.2 Hz, 1H), 7.37 (br. s, 2H), 6.06 (d, J = 2.9 Hz, 1H), 5.31 (dd, J = 6.3 Hz, J = 3.0 Hz, 1H), 4.90 (dd, J = 6.4 Hz, J = 2.9 Hz, 1H), 4.16 (td, J = 5.7 Hz, J = 2.9 Hz, 1H), 3.88 (s, 3H), 3.24–3.12 (m, 2H), 1.49 (s, 3H), 1.27 (s, 3H). |
| T426 | 27516-27677 | Sentence | denotes | 13C NMR (150 MHz, DMSO‑d 6) δ 156.7, 156.2, 152.6, 150.8, 148.3, 140.1, 133.5, 130.3, 119.3, 114.8, 113.4, 107.7, 89.5, 84.2, 82.9, 81.5, 56.8, 44.7, 26.9, 25.1. |
| T427 | 27678-27724 | Sentence | denotes | HRMS (ESI+): m/z calcd for C20H24N7O8S [M+H]+: |
| T428 | 27725-27750 | Sentence | denotes | 522.1407, Found 522.1407. |
| T429 | 27752-27915 | Sentence | denotes | 4.1.24 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-2-nitro-4-(trifluoromethyl)benzene-1-sulfonamide (28) |
| T430 | 27916-28072 | Sentence | denotes | To a solution of 5′-amino-2′,3′-isopropylidene adenosine (280 mg, 0.92 mmol, 1.00 eq) in anhydrous DMF (4.6 mL) was added Et3N (250 μL, 1.83 mmol, 2.00 eq). |
| T431 | 28073-28246 | Sentence | denotes | 2-nitro-4-trifluoromethylbenzenesufonyl chloride (396 mg, 1.37 mmol, 1.50 eq) was added at 0 °C and the reaction mixture was stirred for 4 h at room temperature under argon. |
| T432 | 28247-28317 | Sentence | denotes | The reaction mixture was diluted with AcOEt (30 mL) and water (30 mL). |
| T433 | 28318-28487 | Sentence | denotes | The aqueous layer was extracted with AcOEt (3 × 30 mL) and the combined organic extracts were washed with brine (30 mL), dried over Na2SO4 and concentrated under vacuum. |
| T434 | 28488-28636 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–5% MeOH in DCM) to give 28 (230 mg, 45%) as a dark red solid. |
| T435 | 28637-28664 | Sentence | denotes | Rf 0.34 (8:92 MeOH/CH2Cl2). |
| T436 | 28665-29042 | Sentence | denotes | 1H NMR (500 MHz, DMSO‑d 6) δ 8.93 (t, J = 5.1 Hz, 1H), 8.50 (d, J = 1.8 Hz, 1H), 8.28 (s, 1H), 8.14 (s, 1H), 8.10 (dd, J = 1.6 Hz, J = 8.6 Hz, 1H), 8.04 (d, J = 8.3 Hz), 7.45 (br. s, 2H), 6.11 (d, J = 2.9 Hz, 1H), 5.34 (dd, J = 6.3 Hz, J = 2.9 Hz, 1H), 4.92 (dd, J = 6.3 Hz, J = 3.1 Hz, 1H), 4.20 (td, J = 5.9 Hz, J = 3.1 Hz, 1H), 3.37–3.25 (m, 2H), 1.50 (s, 3H), 1.27 (s, 3H). |
| T437 | 29043-29261 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 156.1, 152.4, 148.4, 147.6, 140.2, 136.4, 133.8, 133.5, 133.2, 133.0, 130.8, 129.4, 125.5, 123.4, 121.2, 119.0, 122.0, 122.0, 119.3, 113.5, 107.7, 89.4, 84.3, 83.0, 81.5, 44.7, 26.9, 25.0. |
| T438 | 29262-29310 | Sentence | denotes | HRMS (ESI+): m/z calcd for C20H21N7O7SF3 [M+H]+: |
| T439 | 29311-29336 | Sentence | denotes | 560.1175, Found 560.1180. |
| T440 | 29338-29490 | Sentence | denotes | 4.1.25 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-4-chloro-3-nitrobenzene-1-sulfonamide (29) |
| T441 | 29491-29676 | Sentence | denotes | Following method A with 5′-amino-2′,3′-isopropylidene adenosine (280 mg, 0.92 mmol, 1.00 eq) and 4-chloro-3-nitrobenzenesufonyl chloride, 29 (346 mg, 72%) was obtained as a brown solid. |
| T442 | 29677-29704 | Sentence | denotes | Rf 0.42 (8:92 MeOH/CH2Cl2). |
| T443 | 29705-30073 | Sentence | denotes | 1H NMR (400 MHz, DMSO‑d 6) δ 8.56 (s, 1H), 8.39 (d, J = 2.1 Hz, 1H), 8.27 (s, 1H), 8.14 (s, 1H), 7.96 (dd, J = 8.5 Hz, J = 2.1 Hz, 1H), 7.90 (d, J = 8.5 Hz, 1H), 7.37 (br. s, 2H), 6.12 (d, J = 2.8 Hz, 1H), 5.34 (dd, J = 6.3 Hz, J = 2.9 Hz, 1H), 4.89 (dd, J = 6.3 Hz, J = 3.1 Hz, 1H) 4.17 (td, J = 5.9 Hz, J = 3.0 Hz, 1H), 3.33–3.18 (m, 2H), 1.51 (s, 3H), 1.29 (s, 3H). |
| T444 | 30074-30236 | Sentence | denotes | 13C NMR (100 MHz, DMSO‑d 6) δ 156.7, 153.0, 148.9, 147.8, 141.1, 140.6, 133.4, 131.6, 129.8, 124.4, 119.7, 114.0, 107.7, 89.8, 84.7, 83.4, 82.0, 44.9, 27.4, 25.6. |
| T445 | 30237-30285 | Sentence | denotes | HRMS (ESI+): m/z calcd for C19H21N7O7SCl [M+H]+: |
| T446 | 30286-30311 | Sentence | denotes | 526.0912, Found 526.0914. |
| T447 | 30313-30603 | Sentence | denotes | 4.1.26 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)-4-methoxy-2-nitrobenzene-1-sulfonamide (30) |
| T448 | 30604-30713 | Sentence | denotes | Following method B with 26 (161 mg, 0.31 mmol, 1.00 eq), 30 (166 mg, 52%) was obtained as a pale white solid. |
| T449 | 30714-30739 | Sentence | denotes | Rf 0.67 (10:90 MeOH/DCM). |
| T450 | 30740-31321 | Sentence | denotes | 1H NMR (500 MHz, CDCl3)) δ 8.286 (s, 1H), 8.292 (s, 1H), 8.14 (s, 1H), 7.82 (s, 1H), 7.66 (d, J = 8.9 Hz, 1H), 6.92 (d, J = 2.6 Hz, 1H), 6.74 (dd, J = 9.0 Hz, J = 2.6 Hz, 1H), 6.01 (d, J = 3.2 Hz, 1H), 5.97–5.88 (m, 5H), 5.31 (dd, J = 6.5 Hz, J = 2.1 Hz, 1H), 4.99 (dd, J = 6.4 Hz, J = 3.7 Hz, 1H), 4.52 (dd, J = 6.1 Hz, J = 4.6 Hz, 1H), 4.43 (dt, J = 8.4 Hz, J = 4.2 Hz, 1H), 4.22 (dd, J = 4.7 Hz, J = 3.2 Hz, 1H), 4.06 (dt, J = 6.1 Hz, J = 3.1 Hz, 1H), 3.97 (dd, J = 11.5 Hz, J = 3.5 Hz, 1H), 3.86–3.49 (m, 10H), 1.55 (s, 3H), 1.33 (s, 3H), 0.90 (br. s, 18H), 0.11–0.05 (m, 12H). |
| T451 | 31322-31598 | Sentence | denotes | 13C NMR (125 MHz, CDCl3) δ 162.8, 155.7, 155.5, 153.2, 152.9, 149.6, 149.1, 149.0, 140.2, 139.7, 133.0, 125.0, 120.4, 120.3, 116.2, 114.7, 109.9, 90.6, 87.4, 84.5, 84.5 (2C), 84.3, 82.6, 82.5, 69.9, 69.6, 61.6, 50.2, 47.2, 27.3, 26.2, 25.9, 25.4, 18.6, 18.2, −4.4, −4.7, −5.3. |
| T452 | 31599-31650 | Sentence | denotes | HRMS (ESI+): m/z calcd for C47H67N12O12SSi2 [M+H]+: |
| T453 | 31651-31668 | Sentence | denotes | 1043.4261, found: |
| T454 | 31669-31679 | Sentence | denotes | 1043.4265. |
| T455 | 31681-31971 | Sentence | denotes | 4.1.27 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)-2-methoxy-4-nitrobenzene-1-sulfonamide (31) |
| T456 | 31972-32081 | Sentence | denotes | Following method B with 27 (185 mg, 0.36 mmol, 1.00 eq), 31 (160 mg, 43%) was obtained as a pale white solid. |
| T457 | 32082-32107 | Sentence | denotes | Rf 0.67 (10:90 MeOH/DCM). |
| T458 | 32108-32605 | Sentence | denotes | 1H NMR (500 MHz, CDCl3) δ 8.30 (s, 1H), 8.29 (s, 1H), 8.16 (br. s, 1H), 7.82 (s, 1H), 7.67 (m, 2H), 7.57–7.43 (m, 2H), 6.16–5.90 (m, 5H), 5.88 (s, 1H), 5.27 (br. s, 1H), 4.94 (dd, J = 6.7 Hz, J = 3.7 Hz, 1H), 4.52 (t, J = 5.4 Hz, 1H), 4.42 (dt, J = 8.7 Hz, J = 4.2 Hz, 1H), 4.20 (dd, J = 4.7 Hz, J = 3.1 Hz, 1H), 4.07 (dt, J = 6.1 Hz, J = 3.0 Hz, 1H), 3.99 (dd, J = 11.5 Hz, J = 3.4 Hz, 1H), 3.92–3.44 (m, 10H), 1.54 (s, 3H), 1.32 (s, 3H), 0.921 (br. s, 9H), 0.918 (br. s, 9H), 0.15–0.05 (m, 12H). |
| T459 | 32606-32881 | Sentence | denotes | 13C NMR (125 MHz, CDCl3) δ 157.1, 155.8, 155.5, 153.2, 152.9, 150.9, 149.5, 148.9, 139.7, 139.6, 134.2, 131.5, 120.4, 120.2, 114.7 (2C), 106.7, 90.5, 87.5, 84.5, 84.4, 84.4, 82.8, 82.6, 70.7, 69.6, 61.5, 56.8, 50.2, 47.1, 27.2, 26.2, 25.9, 25.4, 18.6, 18.2, −4.3, −4.8, −5.2. |
| T460 | 32882-32933 | Sentence | denotes | HRMS (ESI+): m/z calcd for C47H67N12O12SSi2 [M+H]+: |
| T461 | 32934-32951 | Sentence | denotes | 1043.4261, found: |
| T462 | 32952-32962 | Sentence | denotes | 1043.4255. |
| T463 | 32964-33264 | Sentence | denotes | 4.1.28 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)-2-nitro-4-(trifluoromethyl)benzene-1-sulfonamide (32) |
| T464 | 33265-33372 | Sentence | denotes | Following method B with 28 (77 mg, 0.14 mmol, 1.00 eq), 32 (68 mg, 46%) was obtained as a pale white solid. |
| T465 | 33373-33398 | Sentence | denotes | Rf 0.47 (10:90 MeOH/DCM). |
| T466 | 33399-34009 | Sentence | denotes | 1H NMR (500 MHz, CDCl3) δ 8.33 (s, 1H), 8.30 (s, 1H), 8.15 (s, 1H), 7.85 (d, J = 8.2 Hz, 1H), 7.77 (d, J = 1.7 Hz, 1H), 7.76 (s, 1H), 7.54 (dd, J = 8.4 Hz, J = 1.8 Hz, 1H), 5.97 (d, J = 2.8 Hz, 1H), 5.93 (d, J = 1.9 Hz, 1H), 5.74 (br. s, 4H), 5.33 (dd, J = 6.4 Hz, J = 2.0 Hz, 1H), 5.01 (dd, J = 6.4 Hz, J = 3.8 Hz, 1H), 4.50 (dd, J = 6.4 Hz, J = 4.6 Hz, 1H), 4.43 (dt, J = 8.3 Hz, J = 4.0 Hz, 1H), 4.18 (dd, J = 4.7 Hz, J = 2.8 Hz, 1H), 4.01–3.96 (m, 2H), 3.94–3.78 (m, 4H), 3.77–3.66 (m, 2H), 3.56 (dt, J = 15.5 Hz, J = 5.1 Hz, 1H), 1.55 (s, 3H), 1.34 (s, 3H), 0.91 (s, 9H), 0.89 (s, 9H), 0.13–0.02 (m, 12H). |
| T467 | 34010-34365 | Sentence | denotes | 13C NMR (125 MHz, CDCl3) δ 155.6, 155.4, 153.3, 153.0, 149.5, 149.1, 147.9, 140.2, 139.5, 137.4, 135.6, 135.3, 135.0, 134.7, 132.0, 128.3, 128.3, 125.3, 123.2, 121.0, 118.8, 121.7, 121.6, 133.0, 120.4, 120.3, 116.2, 114.8, 109.9, 90.6, 87.5, 84.7, 84.3, 84.1, 82.9, 82.6, 69.6, 69.4, 61.3, 50.2, 47.4, 27.2, 26.2, 25.9, 25.4, 18.6, 18.2, −4.4, −4.8, −5.3. |
| T468 | 34366-34419 | Sentence | denotes | HRMS (ESI+): m/z calcd for C44H64N12O11SF3Si2 [M+H]+: |
| T469 | 34420-34437 | Sentence | denotes | 1081.4029, found: |
| T470 | 34438-34448 | Sentence | denotes | 1081.4034. |
| T471 | 34450-34739 | Sentence | denotes | 4.1.29 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)-4-chloro-3-nitrobenzene-1-sulfonamide (33) |
| T472 | 34740-34849 | Sentence | denotes | Following method B with 29 (230 mg, 0.44 mmol, 1.00 eq), 33 (160 mg, 43%) was obtained as a pale white solid. |
| T473 | 34850-34875 | Sentence | denotes | Rf 0.52 (10:90 MeOH/DCM). |
| T474 | 34876-35412 | Sentence | denotes | 1H NMR (600 MHz, CDCl3) δ 8.29 (s, 1H), 8.28 (s, 1H), 8.116 (2s, 2H), 7.79 (s, 1H), 7.65 (dd, J = 8.4 Hz, J = 2.1 Hz, 1H), 7.39 (d, J = 8.4 Hz, 1H), 6.02–5.93 (m, 6H), 5.36 (dd, J = 6.4 Hz, J = 1.8 Hz, 1H), 5.05 (dd, J = 6.4 Hz, J = 3.8 Hz, 1H), 4.51 (dd, J = 6.1 Hz, J = 4.7 Hz, 1H), 4.44 (dt, J = 8.5 Hz, J = 4.3 Hz, 1H), 4.19 (dd, J = 4.7 Hz, J = 3.0 Hz, 1H), 4.05–3.97 (m, 2H), 3.82 (t, J = 5.5 Hz, 2H), 3.79–3.65 (m, 3H), 3.46 (q, J = 5.3 Hz, 2H), 1.56 (s, 3H), 1.35 (s, 3H), 0.92 (br. s, 9H), 0.90 (br. s, 9H), 0.12–0.05 (m, 12H). |
| T475 | 35413-35683 | Sentence | denotes | 13C NMR (150 MHz, CDCl3) δ 155.8, 155.6, 153.2, 153.1, 149.5, 149.0, 147.6, 140.3, 140.2, 139.4, 132.4, 131.3, 131.2, 124.6, 120.5, 120.2, 114.7, 90.7, 87.4, 85.0, 84.3 (2C), 82.9, 82.6, 69.7, 69.5, 61.4, 50.5, 47.7, 27.2, 26.2, 25.9, 25.4, 18.6, 18.2, −4.4, −4.7, −5.2. |
| T476 | 35684-35737 | Sentence | denotes | HRMS (ESI+): m/z calcd for C43H64N12O11SSi2Cl [M+H]+: |
| T477 | 35738-35755 | Sentence | denotes | 1047.3765, found: |
| T478 | 35756-35766 | Sentence | denotes | 1047.3766. |
| T479 | 35768-36008 | Sentence | denotes | 4.1.30 N-(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)-N-(2-(((2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)ethyl)-4-methoxy-2-nitrobenzenesulfonamide (10) |
| T480 | 36009-36252 | Sentence | denotes | Using method C with 30 (167 mg, 0.16 mmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 10 (25 mg, 20%) was obtained as a white powder with 97% purity determined by HPLC analysis at 260 nm. |
| T481 | 36253-36763 | Sentence | denotes | 1H NMR (500 MHz, DMSO‑d 6) δ 8.32 (s, 1H), 8.28 (s, 1H), 8.13 (s, 2H), 7.77 (d, J = 9.0 Hz, 1H), 7.44 (dd, J = 8.5 Hz, J = 2.6 Hz, 1H), 7.34 (br. s, 2H), 7.29 (br. s, 2H), 6.99 (dd, J = 9.0 Hz, J = 2.6 Hz, 1H), 5.95 (d, J = 5.2 Hz, 1H), 5.83 (d, J = 5.5 Hz, 1H), 5.65 (br. s, 1H), 5.49 (br. s, 1H), 5.38 (t, J = 5.7 Hz, 1H), 5.27 (br. s, 1H), 4.66 (t, J = 5.2 Hz, 1H), 4.37 (t, J = 5.1 Hz, 1H), 4.33–4.26 (m, 1H), 4.17–4.08 (m, 2H), 3.93 (q, J = 3.6 Hz, 1H), 3.84 (s, 3H), 3.80–3.62 (m, 3H), 3.60–3.37 (m, 5H). |
| T482 | 36764-36981 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 162.6, 156.1, 156.2, 152.6, 152.6, 149.3, 149.0, 148.9, 139.9, 139.8, 131.5, 123.3, 119.2 (2C), 116.7, 109.7, 87.8, 86.3, 85.8, 81.8, 81.5, 72.5, 71.5, 68.1, 66.4, 61.1, 56.6, 50.3, 47.1. |
| T483 | 36982-37030 | Sentence | denotes | HRMS (ESI+): m/z calcd for C29H35N12O12S [M+H]+: |
| T484 | 37031-37056 | Sentence | denotes | 775.2218, Found 775.2225. |
| T485 | 37058-37271 | Sentence | denotes | 4.1.31 N-{[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)-2-methoxy-4-nitrobenzene-1-sulfonamide (11) |
| T486 | 37272-37515 | Sentence | denotes | Using method C with 31 (160 mg, 0.15 mmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 11 (15 mg, 13%) was obtained as a white powder with 98% purity determined by HPLC analysis at 260 nm. |
| T487 | 37516-38026 | Sentence | denotes | 1H NMR (500 MHz, DMSO‑d 6) δ 8.32 (s, 1H), 8.28 (s, 1H), 8.13 (s, 2H), 7.77 (d, J = 9.0 Hz, 1H), 7.44 (dd, J = 8.5 Hz, J = 2.6 Hz, 1H), 7.34 (br. s, 2H), 7.29 (br. s, 2H), 6.99 (dd, J = 9.0 Hz, J = 2.6 Hz, 1H), 5.95 (d, J = 5.2 Hz, 1H), 5.83 (d, J = 5.5 Hz, 1H), 5.65 (br. s, 1H), 5.49 (br. s, 1H), 5.38 (t, J = 5.7 Hz, 1H), 5.27 (br. s, 1H), 4.66 (t, J = 5.2 Hz, 1H), 4.37 (t, J = 5.1 Hz, 1H), 4.33–4.27 (m, 1H), 4.17–4.08 (m, 2H), 3.93 (q, J = 3.6 Hz, 1H), 3.84 (s, 3H), 3.80–3.62 (m, 3H), 3.60–3.37 (m, 5H). |
| T488 | 38027-38246 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 156.9, 156.1, 155.9, 152.5, 152.4, 150.6, 149.0, 148.8, 134.0, 139.5, 133.7, 131.0, 119.2, 119.2, 114.4, 107.4, 87.8, 86.2, 85.9, 81.5, 81.4, 72.5, 71.3, 68.9, 66.7, 61.1, 56.8, 50.2, 47.1. |
| T489 | 38247-38295 | Sentence | denotes | HRMS (ESI+): m/z calcd for C29H35N12O12S [M+H]+: |
| T490 | 38296-38321 | Sentence | denotes | 775.2218, Found 775.2220. |
| T491 | 38323-38546 | Sentence | denotes | 4.1.32 N-{[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)-2-nitro-4-(trifluoromethyl)benzene-1-sulfonamide (12) |
| T492 | 38547-38787 | Sentence | denotes | Using method C with (120 mg, 0.11 mmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 12 (18 mg, 20%) was obtained as a white powder with 99% purity determined by HPLC analysis at 260 nm. |
| T493 | 38788-39329 | Sentence | denotes | 1H NMR (500 MHz, DMSO‑d 6) δ 8.47 (d, J = 1.7 Hz, 1H), 8.32 (s, 1H), 8.28 (s, 1H), 8.15 (d, J = 8.3 Hz, 1H), 8.12 (s, 1H), 8.11 (s, 1H), 7.88 (dd, J = 8.6 Hz, J = 1.8 Hz, 1H), 7.36 (br. s, 2H), 7.31 (br. s, 2H), 5.90 (d, J = 5.2 Hz, 1H), 5.82 (d, J = 5.4 Hz, 1H), 5.61 (d, J = 6.0 Hz, 1H), 5.43 (d, J = 5.1 Hz, 1H), 5.38 (dd, J = 6.6 Hz, J = 4.8 Hz, 1H), 5.30 (d, J = 5.3 Hz, 1H), 4.65 (q, J = 5.4 Hz, 1H), 4.37 (t, J = 5.1 Hz, 1H), 4.31 (q, J = 4.7 Hz, 1H), 4.19–4.10 (m, 2H), 3.91 (q, J = 3.6 Hz, 1H), 3.87–3.63 (m, 4H), 3.61–3.45 (m, 4H). |
| T494 | 39330-39604 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 156.2, 156.1, 152.7, 152.6, 149.2, 148.9, 147.7, 139.9, 139.4, 135.9, 133.9, 133.6, 133.3, 133.1, 131.1, 128.9, 128.9, 152.5, 123.3, 121.1, 119.0, 122.0, 121.9, 119.2 (2C), 87.8, 86.3, 85.9, 81.6, 81.5, 72.5, 71.4, 68.8, 67.7, 61.0, 50.0, 47.3. |
| T495 | 39605-39642 | Sentence | denotes | 19F NMR (378 MHz, DMSO‑d 6): δ −62.8. |
| T496 | 39643-39693 | Sentence | denotes | HRMS (ESI+): m/z calcd for C29H32N12O11SF3 [M+H]+: |
| T497 | 39694-39719 | Sentence | denotes | 813.1986, Found 813.1988. |
| T498 | 39721-39933 | Sentence | denotes | 4.1.33 N-{[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)-4-chloro-3-nitrobenzene-1-sulfonamide (13) |
| T499 | 39934-40177 | Sentence | denotes | Using method C with 33 (121 mg, 0.12 mmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 13 (14 mg, 16%) was obtained as a white powder with 98% purity determined by HPLC analysis at 260 nm. |
| T500 | 40178-40714 | Sentence | denotes | 1H NMR (500 MHz, DMSO‑d 6) δ 8.42 (d, J = 2.2 Hz, 1H), 8.34 (s, 1H), 8.32 (s, 1H), 8.144 (s, 1H), 8.140 (s, 1H), 7.96 (dd, J = 8.5 Hz, J = 2.2 Hz, 1H), 7.77 (d, J = 8.5 Hz, 1H), 7.41 (br. s, 2H) 7.35 (br. s, 2H), 5.90 (d, J = 5.2 Hz, 1H), 5.83 (d, J = 5.8 Hz, 1H), 5.59 (d, J = 6.0 Hz, 1H), 5.48–5.31 (m, 2H), 5.25 (d, J = 5.3 Hz, 1H), 4.72 (q, J = 5.5 Hz, 1H), 4.36 (t, J = 5.0 Hz, 1H), 4.29 (q, J = 4.6 Hz, 1H), 4.22–4.08 (m, 2H), 3.87 (q, J = 3.6 Hz, 1H), 3.78–3.70 (m, 2H), 3.67 (dd, J = 12.2 Hz, J = 3.4 Hz, 1H), 3.56–3.29 (m, 5H). |
| T501 | 40715-40928 | Sentence | denotes | 13C NMR (125 MHz, DMSO‑d 6) δ 156.1, 156.0, 152.6, 152.5, 149.3, 148.9, 147.4, 140.1, 139.5, 139.5, 132.7, 131.6, 129.6, 124.3, 119.3, 119.3, 87.6, 86.2, 85.8, 81.8, 81.5, 72.3, 71.3, 68.8, 68.1, 61.4, 50.8, 48.1. |
| T502 | 40929-40979 | Sentence | denotes | HRMS (ESI+): m/z calcd for C28H32N12O11SCl [M+H]+: |
| T503 | 40980-41005 | Sentence | denotes | 779.1723, Found 779.1730. |
| T504 | 41007-41288 | Sentence | denotes | 4.1.34 N-{[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-3-yl]oxy}ethyl)-4-chlorobenzene-1-sulfonamide (34) |
| T505 | 41289-41405 | Sentence | denotes | To a solution of 20 (171 mg, 0.21 mmol, 1.00 eq) in anhydrous DCM (2 mL) was added Et3N (60 μL, 0.41 mmol, 2.00 eq). |
| T506 | 41406-41562 | Sentence | denotes | 4-chlorobenzenesulfonyl chloride (65 mg, 0.31 mmol, 1.50 eq) was added at 0 °C and the reaction mixture was stirred for 3 h at room temperature under argon. |
| T507 | 41563-41692 | Sentence | denotes | Solvents were removed under vacuum and the residue was diluted with DCM (40 mL) and washed with saturated aqueous NaHCO3 (40 mL). |
| T508 | 41693-41860 | Sentence | denotes | The aqueous layer was extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine (30 mL), dried over Na2SO4 and concentrated under vacuum. |
| T509 | 41861-42006 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–4% MeOH in DCM) to give 34 (188 mg, 90%) as a white solid. |
| T510 | 42007-42035 | Sentence | denotes | Rf 0.67 (10:90 MeOH/CH2Cl2). |
| T511 | 42036-42608 | Sentence | denotes | 1H NMR (500 MHz, CDCl3) δ 8.32 (s, 1H), 8.29 (s, 1H), 8.12 (s, 1H), 7.81 (s, 1H), 7.59–7.46 (m, 2H), 7.34–7.22 (m, 2H), 5.97 (d, J = 3.3 Hz, 1H), 5.96–5.88 (m, 5H), 5.41 (dd, J = 6.4 Hz, J = 2.0 Hz, 1H), 5.07 (dd, J = 6.4 Hz, J = 3.5 Hz, 1H), 4.50 (dd, J = 5.9 Hz, J = 4.6 Hz, 1H), 4.46–4.34 (m, 1H), 4.21 (dd, J = 4.7 Hz, J = 3.3 Hz, 1H), 4.03 (dt, J = 6.0 Hz, J = 3.0 Hz, 1H), 3.98 (dd, J = 11.4 Hz, J = 3.5 Hz, 1H), 3.80–3.72 (m, 3H), 3.68 (dd, J = 14.6 Hz, J = 5.6 Hz, 1H), 3.46–3.31 (m, 3H), 1.57 (s, 3H), 1.36 (s, 3H), 0.91 (s, 9H), 0.89 (s, 9H), 0.11–0.03 (m, 12H). |
| T512 | 42609-42864 | Sentence | denotes | 13C NMR (125 MHz, CDCl3) δ 155.8, 155.6, 153.2, 153.1, 149.5, 149.1, 140.2, 139.5, 139.1, 138.0, 129.2, 128.6, 120.5, 120.2, 114.6, 90.9, 87.3, 85.3, 84.5, 84.1, 82.6 (2C), 69.6 (2C), 61.6, 50.7, 48.1, 27.2, 26.1, 25.9, 25.4, 18.6, 18.2, −4.5, −4.7, −5.3. |
| T513 | 42865-42917 | Sentence | denotes | HRMS (ESI+): m/z calcd for C43H65N11O9SSi2Cl [M+H]+: |
| T514 | 42918-42935 | Sentence | denotes | 1002.3909, found: |
| T515 | 42936-42946 | Sentence | denotes | 1002.3928. |
| T516 | 42948-43225 | Sentence | denotes | 4.1.35 9-[(2R,5R)-3-[2-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}[(4-chloro-3-nitrophenyl)methyl]amino)ethoxy]-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-9H-purin-6-amine (35) |
| T517 | 43226-43453 | Sentence | denotes | To a solution of 20 (100 mg, 0.12 mmol, 1.00 eq) in anhydrous DCE (3.5 mL) was added a solution of 4-chloro-3-nitrobenazaldehyde (27 mg, 0.18 mmol, 1.50 eq) in anhydrous DCE (3.5 mL) and acetic acid (10 μL, 0.18 mmol, 1.50 eq). |
| T518 | 43454-43569 | Sentence | denotes | After stirring for 20 min at 40 °C under argon, sodium triacetoxyborohydride (38 mg, 0.18 mmol, 1.50 eq) was added. |
| T519 | 43570-43687 | Sentence | denotes | After stirring at 40 °C for 16 h, the solution was diluted with DCM (30 mL) and washed with saturated aqueous NaHCO3. |
| T520 | 43688-43855 | Sentence | denotes | The aqueous layer was extracted with DCM (3 × 30 mL) and the combined organic extracts were washed with brine (60 mL), dried over Na2SO4 and concentrated under vacuum. |
| T521 | 43856-44001 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–5% MeOH in DCM) to give 35 as a white solid (105 mg, 87%). |
| T522 | 44002-44026 | Sentence | denotes | Rf 0.71 (MeOH/DCM 5:95). |
| T523 | 44027-44623 | Sentence | denotes | 1H NMR (500 MHz, CDCl3) δ 8.27 (s, 1H), 8.18 (s, 1H), 8.15 (s, 1H), 7.82 (br. s, 2H), 7.29–7.27 (m, 2H), 6.22 (br. s, 2H), 6.20 (br. s, 2H), 6.10 (d, J = 3.6 Hz, 1H), 5.99 (d, J = 2.1 Hz, 1H), 5.37 (dd, J = 6.5 Hz, J = 2.1 Hz, 1H), 4.91 (dd, J = 6.5 Hz, J = 3.7 Hz, 1H), 4.48 (t, J = 5.1 Hz, 1H), 4.30 (td, J = 6.7 Hz, J = 3.6 Hz, 1H), 4.22 (t, J = 4.2 Hz, 1H), 4.07 (dt, J = 5.8 Hz, J = 3.0 Hz, 1H), 3.99 (dd, J = 11.5 Hz, J = 3.4 Hz, 1H), 3.81–3.72 (m, 2H), 3.71–3.66 (m, 1H), 3.65–3.61 (m, 2H), 2.90–2.70 (m, 4H), 1.57 (s, 3H), 1.36 (s, 3H), 0.92 (s, 9H), 0.86 (s, 9H), 0.14 – - 0.02 (m, 12H). |
| T524 | 44624-44907 | Sentence | denotes | 13C NMR (125 MHz, CDCl3) δ 155.8, 155.7, 153.1, 153.0, 149.6, 149.0, 147.8, 140.6, 140.1, 139.3, 133.0, 131.4, 125.6, 125.2, 120.3, 120.1, 114.6, 90.8, 87.0, 85.7, 84.9, 84.0, 83.4, 82.8, 69.6, 69.3, 61.8, 58.2, 56.4, 53.5, 27.2, 26.2, 25.8, 25.4, 18.6, 18.2, −4.5, −4.7, −5.2, −5.3. |
| T525 | 44908-44959 | Sentence | denotes | HRMS (ESI+): m/z calcd for C44H66N12O9Si2Cl [M+H]+: |
| T526 | 44960-44976 | Sentence | denotes | 997.4297, found: |
| T527 | 44977-44986 | Sentence | denotes | 997.4327. |
| T528 | 44988-45257 | Sentence | denotes | 4.1.36 9-[(2R,5R)-3-[2-({[(4R,6R)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d] [1,3]dioxol-4-yl]methyl}[(4-chlorophenyl)methyl]amino)ethoxy]-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-9H-purin-6-amine (36) |
| T529 | 45258-45458 | Sentence | denotes | To a solution of 20 (210 mg, 0.25 mmol, 1.00 eq) in anhydrous DCE (7 mL) was added 4-chlorobenzaldehyde (43 mg, 0.38 mmol, 1.50 eq) in anhydrous DCE (7 mL) and acetic acid (18 μL, 0.38 mmol, 1.50 eq). |
| T530 | 45459-45574 | Sentence | denotes | After stirring for 20 min at 40 °C under argon, sodium triacetoxyborohydride (81 mg, 0.38 mmol, 1.50 eq) was added. |
| T531 | 45575-45692 | Sentence | denotes | After stirring at 40 °C for 16 h, the solution was diluted with DCM (50 mL) and washed with saturated aqueous NaHCO3. |
| T532 | 45693-45860 | Sentence | denotes | The aqueous layer was extracted with DCM (3 × 50 mL) and the combined organic extracts were washed with brine (70 mL), dried over Na2SO4 and concentrated under vacuum. |
| T533 | 45861-46017 | Sentence | denotes | The residue was purified by flash column chromatography (silica gel, linear gradient 0–5% MeOH in DCM) to give 36 as a white solid (172 mg, 0.18 mmol, 72%). |
| T534 | 46018-46045 | Sentence | denotes | Rf 0.71 (MeOH/CH2Cl2 5:95). |
| T535 | 46046-46579 | Sentence | denotes | 1H NMR (600 MHz, CDCl3) δ 8.30 (s, 1H), 8.20 (s, 1H), 8.15 (s, 1H), 7.83 (s, 1H), 7.19–7.07 (m, 4H), 6.11 (d, J = 3.7 Hz, 1H), 5.99 (d, J = 2.2 Hz, 1H), 5.97–5.83 (m, 4H), 5.37 (dd, J = 6.5 Hz, J = 2.2 Hz, 1H), 4.85 (dd, J = 6.4 Hz, J = 3.4 Hz, 1H), 4.49 (t, J = 5.1 Hz, 1H), 4.32 (td, J = 6.7 Hz, J = 3.3 Hz, 1H), 4.26 (t, J = 4.2 Hz, 1H), 4.08 (dt, J = 5.9 Hz, J = 3.1 Hz, 1H), 3.98 (dd, J = 11.5 Hz, J = 3.6 Hz, 1H), 3.79–3.47 (m, 5H), 2.84–2.66 (m, 4H), 1.58 (s, 3H), 1.36 (s, 3H), 0.92 (s, 9H), 0.88 (s, 9H), 0.13–0.02 (m, 12H). |
| T536 | 46580-46849 | Sentence | denotes | 13C NMR (150 MHz, CDCl3) δ 155.7, 155.6, 153.1, 153.1, 149.7, 149.3, 140.0, 139.5, 137.8, 132.8, 130.1, 128.4, 120.5, 120.3, 114.4, 91.0, 87.2, 85.7, 84.9, 84.0, 83.5, 82.7, 69.8, 69.5, 61.3, 58.6, 56.4, 53.6, 27.3, 26.2, 25.9, 25.5, 18.6, 18.2, −4.5, −4.7, −5.2, −5.3. |
| T537 | 46850-46901 | Sentence | denotes | HRMS (ESI+): m/z calcd for C44H67N11O7Si2Cl [M+H]+: |
| T538 | 46902-46918 | Sentence | denotes | 952.4447, found: |
| T539 | 46919-46928 | Sentence | denotes | 952.4426. |
| T540 | 46930-47134 | Sentence | denotes | 4.1.37 N-{[(2R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}-N-(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)-4-chlorobenzene-1-sulfonamide (14) |
| T541 | 47135-47378 | Sentence | denotes | Using method C with 34 (150 mg, 0.15 mmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 14 (55 mg, 48%) was obtained as a white powder with 96% purity determined by HPLC analysis at 260 nm. |
| T542 | 47379-47899 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.33 (s, 1H), 8.32 (s, 1H), 8.150 (s, 1H), 8.147 (s, 1H), 7.75–7.68 (m, 2H), 7.53–7.49 (m, 2H), 7.35 (br. s, 2H), 7.28 (br. s, 2H), 5.95 (d, J = 5.5 Hz, 1H), 5.84 (d, J = 5.9 Hz, 1H), 5.52 (d, J = 6.1 Hz, 1H), 5.36 (m, 2H), 5.20 (d, J = 5.2 Hz, 1H), 4.74 (q, J = 5.6 Hz, 1H), 4.39 (t, J = 5.2 Hz, 1H), 4.29 (q, J = 4.7 Hz, 1H), 4.16 (q, J = 4.6 Hz, 1H), 4.11–4.05 (m, 1H), 3.93 (q, J = 3.6 Hz, 1H), 3.73–3.64 (m, 3H), 3.56–3.46 (m, 2H), 3.37–3.29 (m, 3H), 3.22 (dt, J = 14.7 Hz, 6.4 Hz, 1H). |
| T543 | 47900-48099 | Sentence | denotes | 13C NMR (150 MHz, DMSO‑d 6) δ 156.1, 156.0, 152.5, 152.5, 149.3, 148.9, 140.1, 139.5, 138.0, 137.7, 129.2, 128.7, 119.3, 119.3, 87.7, 86.2, 85.9, 82.1, 81.4, 72.2, 71.3, 69.9, 68.3, 61.1, 50.8, 47.7. |
| T544 | 48100-48149 | Sentence | denotes | HRMS (ESI+): m/z calcd for C28H33N11O9SCl [M+H]+: |
| T545 | 48150-48175 | Sentence | denotes | 734.1868, Found 734.1866. |
| T546 | 48177-48377 | Sentence | denotes | 4.1.38 (2R,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)[(4-chloro-3-nitrophenyl)methyl]amino]methyl}oxolane-3,4-diol (15) |
| T547 | 48378-48621 | Sentence | denotes | Using method C with 35 (140 mg, 0.14 mmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 15 (25 mg, 25%) was obtained as a white powder with 99% purity determined by HPLC analysis at 260 nm. |
| T548 | 48622-49213 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.35 (s, 1H), 8.23 (s, 1H), 8.11 (s, 1H), 8.07 (s, 1H), 7.89 (d, J = 1.9 Hz, 1H), 7.50 (d, J = 8.3 Hz, 1H), 7.45 (dd, J = 8.3 Hz, J = 2.0 Hz, 1H), 7.32 (br. s, 2H), 7.24 (br. s, 2H), 5.99 (d, J = 5.9 Hz, 1H), 5.83 (d, J = 5.1 Hz, 1H), 5.51–5.32 (m, 2H), 5.24 (br. s, 1H), 5.13 (br. s, 1H), 4.57 (t, J = 5.2 Hz, 1H), 4.45 (dd, J = 6.1 Hz, J = 4.8 Hz, 1H), 4.30 (t, J = 4.1 Hz, 1H), 4.05 (t, J = 5.0 Hz, 1H), 4.02–3.95 (m, 2H), 3.73–3.63 (m, 4H), 3.58–3.51 (m, 2H), 2.83 (dd, J = 14.0 Hz, J = 4.4 Hz, 1H), 2.73 (dd, J = 14.0 Hz, J = 7.2 Hz, 1H), 2.69–2.63 (m, 2H). |
| T549 | 49214-49431 | Sentence | denotes | 13C NMR (150 MHz, DMSO‑d 6) δ 156.1, 156.0, 152.5 (2C), 149.3, 148.9, 147.2, 140.1, 139.8, 139.6, 133.7, 131.0, 125.0, 122.9, 119.3, 119.2, 87.8, 86.2, 86.1, 82.2, 81.3, 72.4, 71.8, 68.9, 68.1, 61.3, 56.8, 56.0, 53.0. |
| T550 | 49432-49480 | Sentence | denotes | HRMS (ESI+): m/z calcd for C29H34N12O9Cl [M+H]+: |
| T551 | 49481-49506 | Sentence | denotes | 729.2255, Found 729.2256. |
| T552 | 49508-49700 | Sentence | denotes | 4.1.39 (2R,5R)-2-(6-amino-9H-purin-9-yl)-5-{[(2-{[(2R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}ethyl)[(4-chlorophenyl)methyl]amino]methyl}oxolane-3,4-diol (16) |
| T553 | 49701-49944 | Sentence | denotes | Using method C with 36 (172 mg, 0.18 mmol, 1.00 eq) and a 0–40% linear gradient of acetonitrile in TEAAc buffer 50 mM, pH 7 for purification, 16 (45 mg, 37%) was obtained as a white powder with 98% purity determined by HPLC analysis at 260 nm. |
| T554 | 49945-50519 | Sentence | denotes | 1H NMR (600 MHz, DMSO‑d 6) δ 8.36 (s, 1H), 8.25 (s, 1H), 8.13 (s, 1H), 8.11 (s, 1H), 7.34 (br. s, 2H), 7.25 (br. s, 2H), 7.23–7.17 (m, 2H), 7.17–7.11 (m, 2H), 6.00 (d, J = 6.2 Hz, 1H), 5.84 (d, J = 5.0 Hz, 1H), 5.45–5.39 (m, 2H), 5.27 (d, J = 4.8 Hz, 1H), 5.12 (d, J = 5.4 Hz, 1H), 4.58 (q, J = 5.5 Hz, 1H), 4.48 (dd, J = 6.2 Hz, J = 4.8 Hz, 1H), 4.30 (td, J = 4.6 Hz, J = 2.9 Hz, 1H), 4.04 (q, J = 5.1 Hz, 1H), 4.02–3.96 (m, 2H), 3.70–3.63 (m, 2H), 3.60–3.48 (m, 4H), 2.80 (dd, J = 14.0 Hz, J = 4.5 Hz, 1H), 2.67 (dd, J = 13.9 Hz, J = 7.0 Hz, 1H), 2.61 (q, J = 6.1 Hz, 2H). |
| T555 | 50520-50727 | Sentence | denotes | 13C NMR (150 MHz, DMSO‑d 6) δ 156.2, 156.0, 152.6, 152.5, 149.3, 149.0, 139.8, 139.7, 138.2, 131.1, 130.4, 127.8, 119.3, 119.16, 87.67, 86.3, 86.1, 82.4, 81.2, 72.4, 71.8, 69.0, 67.5, 61.5, 57.5, 55.8, 52.9. |
| T556 | 50728-50776 | Sentence | denotes | HRMS (ESI+): m/z calcd for C29H35N11O7Cl [M+H]+: |
| T557 | 50777-50802 | Sentence | denotes | 684.2404, Found 684.2398. |
| T558 | 50804-50860 | Sentence | denotes | 4.2 Expression and purification of recombinant proteins |
| T559 | 50861-51016 | Sentence | denotes | SARS-CoV nsp14 and human RNA N7-methyltransferase (hRNMT) coding sequences were cloned in fusion with a N-terminus hexa-histidine tag in Gateway® plasmids. |
| T560 | 51017-51118 | Sentence | denotes | The proteins were expressed in E. coli and purified following previously described protocols [33,39]. |
| T561 | 51119-51246 | Sentence | denotes | Vaccinia virus capping enzyme (D1/D12 complex) and mRNA Cap 2′-O-methyltransferase (VP39) were purchased (New England Biolabs). |
| T562 | 51248-51285 | Sentence | denotes | 4.3 MTase filter binding assay (FBA) |
| T563 | 51286-51451 | Sentence | denotes | The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter binding assay, performed according to the method described previously [40]. |
| T564 | 51452-51747 | Sentence | denotes | Assays were carried out in reaction mixture [40 mM Tris-HCl (pH 8.0), 1 mM DTT, 1 mM MgCl2, 2 μM SAM and 0.1 μM 3H-SAM (PerkinElmer)] in the presence of 0.7 μM GpppAC4 synthetic RNA and SARS-CoV nsp14 (50 nM), vaccinia virus capping enzyme (D1-D12) (41 U), or human RNA N7 MTase (hRNMT) (50 nM). |
| T565 | 51748-51904 | Sentence | denotes | The enzymes were first mixed with compounds suspended in 100% DMSO (5% final DMSO) before the addition of RNA substrate and SAM and then incubated at 30 °C. |
| T566 | 51905-51965 | Sentence | denotes | Control reactions were performed in the presence of 5% DMSO. |
| T567 | 51966-52055 | Sentence | denotes | Reactions mixtures were stopped after 30 min by their 10-fold dilution in ice-cold water. |
| T568 | 52056-52183 | Sentence | denotes | Samples were transferred to diethylaminoethyl (DEAE) filtermat (PerkinElmer) using a Filtermat Harvester (Packard Instruments). |
| T569 | 52184-52300 | Sentence | denotes | The RNA-retaining mats were washed twice with 10 mM ammonium formate pH 8.0, twice with water and once with ethanol. |
| T570 | 52301-52493 | Sentence | denotes | They were soaked with scintillation fluid (PerkinElmer), and 3H-methyl transfer to the RNA substrates was determined using a Wallac MicroBeta TriLux Liquid Scintillation Counter (PerkinElmer). |
| T571 | 52494-52645 | Sentence | denotes | For IC50 measurements, values were normalized and fitted with Prism (GraphPad software) using the following equation: Y = 100/(1+((X/IC50)^Hillslope)). |
| T572 | 52646-52748 | Sentence | denotes | IC50 is defined as the inhibitory compound concentration that causes 50% reduction in enzyme activity. |
| T573 | 52750-52794 | Sentence | denotes | 4.4 Differential scanning fluorimetry (DSF) |
| T574 | 52795-53009 | Sentence | denotes | The thermal stabilization of the native protein structure upon ligand binding was monitored by differential scanning fluorimetry, performed according to the method described previously [34] with some modifications. |
| T575 | 53010-53227 | Sentence | denotes | Reaction mixture (25 μL) consisted of 20 mM HEPES (pH 7.5), 150 mM NaCl, 1X SYPRO orange dye (Invitrogen), 5 μM SARS-CoV nsp14 protein and 1 mM compound previously dissolved in 100% DMSO or water (SAM and Sinefungin). |
| T576 | 53228-53354 | Sentence | denotes | The protein was first mixed with compound before the addition of the dye and incubated in 96-well white microplates (Bio-Rad). |
| T577 | 53355-53491 | Sentence | denotes | Fluorescence intensities were measured from 20 to 95 °C with a ramp rate of 0.2 °C/min using a Real-Time PCR detection system (Bio-Rad). |
| T578 | 53492-53552 | Sentence | denotes | Control reactions were performed in the presence of 5% DMSO. |
| T579 | 53553-53714 | Sentence | denotes | Fluorescence intensities were plotted as a function of temperature and melting temperature (T m) was determined by curve-fitting using Prism (GraphPad software). |
| T580 | 53715-53898 | Sentence | denotes | The apparent affinity constant (KD) for compound 13 was calculated by nonlinear regression analysis with one site-specific binding equation Hill slope using Prism (GraphPad software). |
| T581 | 53900-53922 | Sentence | denotes | 4.5 Molecular docking |
| T582 | 53923-54076 | Sentence | denotes | All calculations were performed using Autodock vina (The Scripps Research Institute, La Jolla, CA) on a MSI computer with a 2.30 GHz Intel Core i5-8300H. |
| T583 | 54077-54183 | Sentence | denotes | The solved X-ray crystal structure of SARS-CoV nsp14 (PDB 5C8T) was used as a static receptor for docking. |
| T584 | 54184-54298 | Sentence | denotes | Both the co-crystalized ligand SAM and ions were removed from the SARS-CoV nsp14 protein using VMD 1.9.3 software. |
| T585 | 54299-54376 | Sentence | denotes | The ligand structures were drawn and minimized using MarvinSketch (ChemAxon). |
| T586 | 54377-54513 | Sentence | denotes | Targeted protein and ligand structures with polar hydrogens were converted to the required PDBQT format using MGL Tools (version 1.5.6). |
| T587 | 54514-54660 | Sentence | denotes | The docking was performed with a search box located at x = −11.155, y = −40.77, z = −3.688 coordinates, with a search box size of 25 × 25 × 25 Å3. |
| T588 | 54661-54731 | Sentence | denotes | After calculations, PDB files were analyzed using Pymol (version 2.3). |
| T589 | 54733-54753 | Sentence | denotes | 4.6 Accession codes |
| T590 | 54754-54800 | Sentence | denotes | PDB code for SARS-CoV nsp14 bound SAM is 5C8T. |
| T591 | 54801-54837 | Sentence | denotes | PDB code for SARS-CoV nsp14 is 5NFY. |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32563813-17259217-29105596 | 51111-51113 | 17259217 | denotes | 33 |
| 32563813-17853878-29105597 | 52981-52983 | 17853878 | denotes | 34 |