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PMC:7291971 / 33399-34009 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T707 53-63 CHEBI:28748;CHEBI:28748 denotes adenosines
T708 93-101 SP_10 denotes SARS-CoV
T709 430-438 SP_10 denotes SARS-CoV
T710 439-444 PR:000000125 denotes nsp14
T711 502-512 SP_7 denotes SARS-CoV-2
T712 513-518 PR:000000125 denotes nsp14
T713 574-580 SO:0001026 denotes genome
T714 593-603 SP_7 denotes SARS-CoV-2
T6725 53-63 CHEBI:28748;CHEBI:28748 denotes adenosines
T96719 93-101 SP_10 denotes SARS-CoV
T5588 430-438 SP_10 denotes SARS-CoV
T96029 439-444 PR:000000125 denotes nsp14
T31767 502-512 SP_7 denotes SARS-CoV-2
T33421 513-518 PR:000000125 denotes nsp14
T98006 574-580 SO:0001026 denotes genome
T89107 593-603 SP_7 denotes SARS-CoV-2

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T99 346-350 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T100 519-526 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T101 574-580 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
550 53-63 Chemical denotes adenosines MESH:D000241
551 166-176 Chemical denotes sinefungin MESH:C006235

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T92 93-101 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T93 430-438 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T94 502-510 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T95 593-601 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T251 81-89 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T252 186-187 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T253 286-294 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T254 533-535 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T558 53-63 Chemical denotes adenosines http://purl.obolibrary.org/obo/CHEBI_22260
T559 166-176 Chemical denotes sinefungin http://purl.obolibrary.org/obo/CHEBI_45453
T560 338-341 Chemical denotes SAM http://purl.obolibrary.org/obo/CHEBI_15414|http://purl.obolibrary.org/obo/CHEBI_67040
T562 519-526 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T240 213-376 Sentence denotes Thermal shift assays and molecular modeling indicate that the inhibitory activity is likely due to the binding of 13 to both SAM and mRNA binding pockets of nsp14.
T241 377-561 Sentence denotes It is quite interesting to note that all residues of SARS-CoV nsp14 involved in the binding of 13 are fully conserved in the SARS-CoV-2 nsp14 protein (Fig. S1, Supporting Information).