PMC:7291971 / 32964-33264 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T698","span":{"begin":37,"end":46},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T699","span":{"begin":66,"end":71},"obj":"SP_6;NCBITaxon:9606"},{"id":"T700","span":{"begin":181,"end":192},"obj":"NCBITaxon:11118"},{"id":"T701","span":{"begin":237,"end":245},"obj":"SO:0000853"},{"id":"T702","span":{"begin":254,"end":259},"obj":"NCBITaxon:10239"},{"id":"T54566","span":{"begin":37,"end":46},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T98305","span":{"begin":66,"end":71},"obj":"SP_6;NCBITaxon:9606"},{"id":"T14451","span":{"begin":181,"end":192},"obj":"NCBITaxon:11118"},{"id":"T51183","span":{"begin":237,"end":245},"obj":"SO:0000853"},{"id":"T79023","span":{"begin":254,"end":259},"obj":"NCBITaxon:10239"}],"text":"ionally, we also observed that these compounds barely inhibit the human RNA N7 MTase, an important feature given that the lack of antiviral specificity represents a common issue in coronavirus antiviral discovery. Indeed, the structural homology between viral and cellular MTases often impairs the di"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T98","span":{"begin":72,"end":75},"obj":"Body_part"}],"attributes":[{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"ionally, we also observed that these compounds barely inhibit the human RNA N7 MTase, an important feature given that the lack of antiviral specificity represents a common issue in coronavirus antiviral discovery. Indeed, the structural homology between viral and cellular MTases often impairs the di"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T248","span":{"begin":66,"end":71},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T249","span":{"begin":163,"end":164},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"ionally, we also observed that these compounds barely inhibit the human RNA N7 MTase, an important feature given that the lack of antiviral specificity represents a common issue in coronavirus antiviral discovery. Indeed, the structural homology between viral and cellular MTases often impairs the di"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T554","span":{"begin":130,"end":139},"obj":"Chemical"},{"id":"T555","span":{"begin":193,"end":202},"obj":"Chemical"}],"attributes":[{"id":"A554","pred":"chebi_id","subj":"T554","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A555","pred":"chebi_id","subj":"T555","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"ionally, we also observed that these compounds barely inhibit the human RNA N7 MTase, an important feature given that the lack of antiviral specificity represents a common issue in coronavirus antiviral discovery. Indeed, the structural homology between viral and cellular MTases often impairs the di"}