PMC:7291971 / 30552-30726 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T659","span":{"begin":99,"end":108},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T660","span":{"begin":135,"end":150},"obj":"CHEBI:50728;CHEBI:50728"},{"id":"T661","span":{"begin":166,"end":173},"obj":"CHEBI:33543;CHEBI:33543"}],"text":"This constraint may explain the difference in activity (IC50) and stabilizing effect (T m) between compounds 13 and 15 that contains a methylene group instead of the sulfone."}

{"project":"LitCovid-PubTator","denotations":[{"id":"531","span":{"begin":166,"end":173},"obj":"Chemical"}],"attributes":[{"id":"A531","pred":"tao:has_database_id","subj":"531","obj":"MESH:D013450"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"This constraint may explain the difference in activity (IC50) and stabilizing effect (T m) between compounds 13 and 15 that contains a methylene group instead of the sulfone."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T239","span":{"begin":46,"end":54},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T240","span":{"begin":133,"end":134},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"This constraint may explain the difference in activity (IC50) and stabilizing effect (T m) between compounds 13 and 15 that contains a methylene group instead of the sulfone."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T516","span":{"begin":135,"end":150},"obj":"Chemical"},{"id":"T517","span":{"begin":135,"end":144},"obj":"Chemical"},{"id":"T519","span":{"begin":145,"end":150},"obj":"Chemical"},{"id":"T520","span":{"begin":166,"end":173},"obj":"Chemical"}],"attributes":[{"id":"A516","pred":"chebi_id","subj":"T516","obj":"http://purl.obolibrary.org/obo/CHEBI_50728"},{"id":"A517","pred":"chebi_id","subj":"T517","obj":"http://purl.obolibrary.org/obo/CHEBI_29357"},{"id":"A518","pred":"chebi_id","subj":"T517","obj":"http://purl.obolibrary.org/obo/CHEBI_29358"},{"id":"A519","pred":"chebi_id","subj":"T519","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A520","pred":"chebi_id","subj":"T520","obj":"http://purl.obolibrary.org/obo/CHEBI_35850"}],"text":"This constraint may explain the difference in activity (IC50) and stabilizing effect (T m) between compounds 13 and 15 that contains a methylene group instead of the sulfone."}

{"project":"LitCovid-sentences","denotations":[{"id":"T220","span":{"begin":0,"end":174},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This constraint may explain the difference in activity (IC50) and stabilizing effect (T m) between compounds 13 and 15 that contains a methylene group instead of the sulfone."}