PMC:7291971 / 28665-29042 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T633","span":{"begin":175,"end":183},"obj":"SP_10"},{"id":"T634","span":{"begin":278,"end":287},"obj":"CHEBI:37886;CHEBI:37886"},{"id":"T635","span":{"begin":303,"end":312},"obj":"CHEBI:28748;CHEBI:28748"},{"id":"T31763","span":{"begin":71,"end":88},"obj":"CHEBI:8102;CHEBI:8102"},{"id":"T69050","span":{"begin":127,"end":139},"obj":"SO:0000409"},{"id":"T17926","span":{"begin":212,"end":218},"obj":"CHEBI:30396;CHEBI:30396"},{"id":"T63901","span":{"begin":230,"end":239},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T43396","span":{"begin":249,"end":258},"obj":"CHEBI:36357;CHEBI:36357"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T87","span":{"begin":14,"end":17},"obj":"Body_part"},{"id":"T88","span":{"begin":25,"end":28},"obj":"Body_part"}],"attributes":[{"id":"A87","pred":"fma_id","subj":"T87","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A88","pred":"fma_id","subj":"T88","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"LitCovid-PubTator","denotations":[{"id":"506","span":{"begin":278,"end":287},"obj":"Chemical"},{"id":"507","span":{"begin":303,"end":312},"obj":"Chemical"}],"attributes":[{"id":"A506","pred":"tao:has_database_id","subj":"506","obj":"MESH:D000241"},{"id":"A507","pred":"tao:has_database_id","subj":"507","obj":"MESH:D000241"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T86","span":{"begin":175,"end":183},"obj":"Disease"}],"attributes":[{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T229","span":{"begin":59,"end":60},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T230","span":{"begin":215,"end":217},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T231","span":{"begin":235,"end":237},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T479","span":{"begin":34,"end":37},"obj":"Chemical"},{"id":"T481","span":{"begin":149,"end":152},"obj":"Chemical"},{"id":"T483","span":{"begin":205,"end":207},"obj":"Chemical"},{"id":"T484","span":{"begin":225,"end":227},"obj":"Chemical"},{"id":"T485","span":{"begin":278,"end":287},"obj":"Chemical"},{"id":"T486","span":{"begin":303,"end":312},"obj":"Chemical"},{"id":"T487","span":{"begin":316,"end":319},"obj":"Chemical"}],"attributes":[{"id":"A479","pred":"chebi_id","subj":"T479","obj":"http://purl.obolibrary.org/obo/CHEBI_15414"},{"id":"A480","pred":"chebi_id","subj":"T479","obj":"http://purl.obolibrary.org/obo/CHEBI_67040"},{"id":"A481","pred":"chebi_id","subj":"T481","obj":"http://purl.obolibrary.org/obo/CHEBI_15414"},{"id":"A482","pred":"chebi_id","subj":"T481","obj":"http://purl.obolibrary.org/obo/CHEBI_67040"},{"id":"A483","pred":"chebi_id","subj":"T483","obj":"http://purl.obolibrary.org/obo/CHEBI_141439"},{"id":"A484","pred":"chebi_id","subj":"T484","obj":"http://purl.obolibrary.org/obo/CHEBI_141439"},{"id":"A485","pred":"chebi_id","subj":"T485","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"},{"id":"A486","pred":"chebi_id","subj":"T486","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"},{"id":"A487","pred":"chebi_id","subj":"T487","obj":"http://purl.obolibrary.org/obo/CHEBI_15414"},{"id":"A488","pred":"chebi_id","subj":"T487","obj":"http://purl.obolibrary.org/obo/CHEBI_67040"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"2_test","denotations":[{"id":"32563813-26159422-29105591","span":{"begin":215,"end":217},"obj":"26159422"},{"id":"32563813-29279395-29105592","span":{"begin":235,"end":237},"obj":"29279395"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"LitCovid-sentences","denotations":[{"id":"T206","span":{"begin":114,"end":208},"obj":"Sentence"},{"id":"T207","span":{"begin":209,"end":228},"obj":"Sentence"},{"id":"T208","span":{"begin":229,"end":240},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}

{"project":"MyTest","denotations":[{"id":"32563813-26159422-29105591","span":{"begin":215,"end":217},"obj":"26159422"},{"id":"32563813-29279395-29105592","span":{"begin":235,"end":237},"obj":"29279395"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":" receptor cap RNA (GpppA-RNA) and SAM bind in proximity in a highly constricted pocket to achieve methyltransfer. The compound 13 was modeled in the SAM binding pocket of the SARS-CoV nsp14 structure (PDB ID: 5C8T [35] \u0026 PDB ID: 5NFY [36]). At first sight, the overlay of the N-adenosine of 13 with the adenosine of SAM bounded structure is suitable (Supporting Information, Fi"}