PMC:7291971 / 22273-22529 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T497","span":{"begin":53,"end":60},"obj":"CHEBI:33543;CHEBI:33543"},{"id":"T498","span":{"begin":71,"end":73},"obj":"CHEBI:36927;CHEBI:36927"},{"id":"T499","span":{"begin":92,"end":107},"obj":"CHEBI:50728;CHEBI:50728"},{"id":"T500","span":{"begin":111,"end":120},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T501","span":{"begin":164,"end":183},"obj":"CHEBI:57472;CHEBI:57472"}],"text":"Finally, the resulting decreased inhibition when the sulfone moiety of 14 was replaced by a methylene group in compounds 15 and 16 stressed the importance of the N-arylsulfonylbenzene motif in the dinucleoside structure to maintain an effective inhibition."}

{"project":"LitCovid-PubTator","denotations":[{"id":"411","span":{"begin":53,"end":60},"obj":"Chemical"},{"id":"412","span":{"begin":162,"end":183},"obj":"Chemical"},{"id":"413","span":{"begin":197,"end":209},"obj":"Chemical"}],"attributes":[{"id":"A411","pred":"tao:has_database_id","subj":"411","obj":"MESH:D013450"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Finally, the resulting decreased inhibition when the sulfone moiety of 14 was replaced by a methylene group in compounds 15 and 16 stressed the importance of the N-arylsulfonylbenzene motif in the dinucleoside structure to maintain an effective inhibition."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T182","span":{"begin":90,"end":91},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Finally, the resulting decreased inhibition when the sulfone moiety of 14 was replaced by a methylene group in compounds 15 and 16 stressed the importance of the N-arylsulfonylbenzene motif in the dinucleoside structure to maintain an effective inhibition."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T396","span":{"begin":53,"end":60},"obj":"Chemical"},{"id":"T397","span":{"begin":92,"end":107},"obj":"Chemical"},{"id":"T398","span":{"begin":92,"end":101},"obj":"Chemical"},{"id":"T400","span":{"begin":102,"end":107},"obj":"Chemical"}],"attributes":[{"id":"A396","pred":"chebi_id","subj":"T396","obj":"http://purl.obolibrary.org/obo/CHEBI_35850"},{"id":"A397","pred":"chebi_id","subj":"T397","obj":"http://purl.obolibrary.org/obo/CHEBI_50728"},{"id":"A398","pred":"chebi_id","subj":"T398","obj":"http://purl.obolibrary.org/obo/CHEBI_29357"},{"id":"A399","pred":"chebi_id","subj":"T398","obj":"http://purl.obolibrary.org/obo/CHEBI_29358"},{"id":"A400","pred":"chebi_id","subj":"T400","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"}],"text":"Finally, the resulting decreased inhibition when the sulfone moiety of 14 was replaced by a methylene group in compounds 15 and 16 stressed the importance of the N-arylsulfonylbenzene motif in the dinucleoside structure to maintain an effective inhibition."}

{"project":"LitCovid-sentences","denotations":[{"id":"T156","span":{"begin":0,"end":256},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Finally, the resulting decreased inhibition when the sulfone moiety of 14 was replaced by a methylene group in compounds 15 and 16 stressed the importance of the N-arylsulfonylbenzene motif in the dinucleoside structure to maintain an effective inhibition."}