PMC:7291971 / 16259-16528 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T368","span":{"begin":16,"end":17},"obj":"CHEBI:75508;CHEBI:75508"},{"id":"T369","span":{"begin":17,"end":18},"obj":"CHEBI:82321;CHEBI:82321"},{"id":"T370","span":{"begin":19,"end":24},"obj":"CHEBI:46882;CHEBI:46882"},{"id":"T371","span":{"begin":24,"end":26},"obj":"CHEBI:75508;CHEBI:75508"},{"id":"T372","span":{"begin":26,"end":27},"obj":"CHEBI:52029;CHEBI:52029"},{"id":"T373","span":{"begin":27,"end":29},"obj":"CHEBI:75508;CHEBI:75508"},{"id":"T374","span":{"begin":29,"end":30},"obj":"CHEBI:52029;CHEBI:52029"},{"id":"T375","span":{"begin":30,"end":45},"obj":"CHEBI:53250;CHEBI:53250"},{"id":"T376","span":{"begin":46,"end":55},"obj":"CHEBI:22260;CHEBI:22260"},{"id":"T377","span":{"begin":135,"end":155},"obj":"CHEBI:53325;CHEBI:53325"},{"id":"T378","span":{"begin":156,"end":164},"obj":"CHEBI:17996;CHEBI:17996"},{"id":"T379","span":{"begin":165,"end":173},"obj":"CHEBI:33893;CHEBI:33893"},{"id":"T380","span":{"begin":209,"end":219},"obj":"CHEBI:22260;CHEBI:22260"}],"text":"The reaction of 5′-amino-2′,3′-isopropylidene adenosine [23] with four diversely substituted (OMe, CF3, Cl) and commercially available nitrobenzenesulfonyl chloride reagents afforded the corresponding N-nosyl adenosines 26–29 with 40–72% yield [[27], [28], [29], [30]]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"333","span":{"begin":16,"end":45},"obj":"Chemical"},{"id":"334","span":{"begin":46,"end":55},"obj":"Chemical"},{"id":"335","span":{"begin":99,"end":102},"obj":"Chemical"},{"id":"336","span":{"begin":135,"end":164},"obj":"Chemical"},{"id":"337","span":{"begin":201,"end":219},"obj":"Chemical"}],"attributes":[{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"MESH:D000241"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The reaction of 5′-amino-2′,3′-isopropylidene adenosine [23] with four diversely substituted (OMe, CF3, Cl) and commercially available nitrobenzenesulfonyl chloride reagents afforded the corresponding N-nosyl adenosines 26–29 with 40–72% yield [[27], [28], [29], [30]]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T138","span":{"begin":104,"end":106},"obj":"http://purl.obolibrary.org/obo/CLO_0052906"},{"id":"T139","span":{"begin":246,"end":248},"obj":"http://purl.obolibrary.org/obo/CLO_0050509"}],"text":"The reaction of 5′-amino-2′,3′-isopropylidene adenosine [23] with four diversely substituted (OMe, CF3, Cl) and commercially available nitrobenzenesulfonyl chloride reagents afforded the corresponding N-nosyl adenosines 26–29 with 40–72% yield [[27], [28], [29], [30]]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T299","span":{"begin":19,"end":24},"obj":"Chemical"},{"id":"T300","span":{"begin":31,"end":45},"obj":"Chemical"},{"id":"T301","span":{"begin":46,"end":55},"obj":"Chemical"},{"id":"T302","span":{"begin":104,"end":106},"obj":"Chemical"},{"id":"T303","span":{"begin":156,"end":164},"obj":"Chemical"},{"id":"T304","span":{"begin":165,"end":173},"obj":"Chemical"},{"id":"T305","span":{"begin":209,"end":219},"obj":"Chemical"}],"attributes":[{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A300","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_29858"},{"id":"A301","pred":"chebi_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/CHEBI_16335"},{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_23116"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_17996"},{"id":"A304","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_33893"},{"id":"A305","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_22260"}],"text":"The reaction of 5′-amino-2′,3′-isopropylidene adenosine [23] with four diversely substituted (OMe, CF3, Cl) and commercially available nitrobenzenesulfonyl chloride reagents afforded the corresponding N-nosyl adenosines 26–29 with 40–72% yield [[27], [28], [29], [30]]."}

{"project":"2_test","denotations":[{"id":"32563813-7086841-29105579","span":{"begin":57,"end":59},"obj":"7086841"},{"id":"32563813-22424977-29105580","span":{"begin":246,"end":248},"obj":"22424977"},{"id":"32563813-30354101-29105581","span":{"begin":252,"end":254},"obj":"30354101"},{"id":"32563813-12723945-29105582","span":{"begin":258,"end":260},"obj":"12723945"},{"id":"32563813-23335289-29105583","span":{"begin":264,"end":266},"obj":"23335289"}],"text":"The reaction of 5′-amino-2′,3′-isopropylidene adenosine [23] with four diversely substituted (OMe, CF3, Cl) and commercially available nitrobenzenesulfonyl chloride reagents afforded the corresponding N-nosyl adenosines 26–29 with 40–72% yield [[27], [28], [29], [30]]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T101","span":{"begin":0,"end":269},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The reaction of 5′-amino-2′,3′-isopropylidene adenosine [23] with four diversely substituted (OMe, CF3, Cl) and commercially available nitrobenzenesulfonyl chloride reagents afforded the corresponding N-nosyl adenosines 26–29 with 40–72% yield [[27], [28], [29], [30]]."}

{"project":"MyTest","denotations":[{"id":"32563813-7086841-29105579","span":{"begin":57,"end":59},"obj":"7086841"},{"id":"32563813-22424977-29105580","span":{"begin":246,"end":248},"obj":"22424977"},{"id":"32563813-30354101-29105581","span":{"begin":252,"end":254},"obj":"30354101"},{"id":"32563813-12723945-29105582","span":{"begin":258,"end":260},"obj":"12723945"},{"id":"32563813-23335289-29105583","span":{"begin":264,"end":266},"obj":"23335289"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"The reaction of 5′-amino-2′,3′-isopropylidene adenosine [23] with four diversely substituted (OMe, CF3, Cl) and commercially available nitrobenzenesulfonyl chloride reagents afforded the corresponding N-nosyl adenosines 26–29 with 40–72% yield [[27], [28], [29], [30]]."}