PMC:7291971 / 1088-1635 JSON TXT

Annnotations TAB JSON ListView MergeView

Id	Subject	Object	Predicate	Lexical cue
T19	55-67	NCBITaxon:31032	denotes	flaviviruses
T20	71-79	SP_10	denotes	SARS-CoV
T21	161-169	SP_10	denotes	SARS-CoV
T22	245-250	PR:000000125	denotes	nsp14
T23	251-260	CHEBI:35222;CHEBI:35222	denotes	inhibitor
T24	349-358	CHEBI:35222;CHEBI:35222	denotes	inhibitor
T25	408-417	CHEBI:35222;CHEBI:35222	denotes	inhibitor
T26	482-485	GO:0008541	denotes	cap
T27	490-503	SO:0000409	denotes	binding sites
T28	521-529	SP_10	denotes	SARS-CoV
T53306	55-67	NCBITaxon:31032	denotes	flaviviruses
T48802	71-79	SP_10	denotes	SARS-CoV
T86425	161-169	SP_10	denotes	SARS-CoV
T66103	245-250	PR:000000125	denotes	nsp14
T45404	251-260	CHEBI:35222;CHEBI:35222	denotes	inhibitor
T10534	349-358	CHEBI:35222;CHEBI:35222	denotes	inhibitor
T99394	408-417	CHEBI:35222;CHEBI:35222	denotes	inhibitor
T71458	482-485	GO:0008541	denotes	cap
T73912	490-503	SO:0000409	denotes	binding sites
T91482	521-529	SP_10	denotes	SARS-CoV

Id	Subject	Object	Predicate	Lexical cue	fma_id
T8	461-471	Body_part	denotes	methionine	http://purl.org/sig/ont/fma/fma82759
T9	486-489	Body_part	denotes	RNA	http://purl.org/sig/ont/fma/fma67095

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
13	360-370	Chemical	denotes	sinefungin	MESH:C006235
14	461-471	Chemical	denotes	methionine	MESH:D008715
15	473-476	Chemical	denotes	SAM	MESH:D012436

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T4	71-79	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T5	161-169	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T6	521-529	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091

Id	Subject	Object	Predicate	Lexical cue
T6	17-23	http://purl.obolibrary.org/obo/CLO_0001658	denotes	active
T7	238-244	http://purl.obolibrary.org/obo/CLO_0001658	denotes	active
T8	427-428	http://purl.obolibrary.org/obo/CLO_0001020	denotes	a

Id	Subject	Object	Predicate	Lexical cue	chebi_id
T13	251-260	Chemical	denotes	inhibitor	http://purl.obolibrary.org/obo/CHEBI_35222
T14	349-358	Chemical	denotes	inhibitor	http://purl.obolibrary.org/obo/CHEBI_35222
T15	360-370	Chemical	denotes	sinefungin	http://purl.obolibrary.org/obo/CHEBI_45453
T16	408-417	Chemical	denotes	inhibitor	http://purl.obolibrary.org/obo/CHEBI_35222
T17	450-471	Chemical	denotes	S-adenosyl methionine	http://purl.obolibrary.org/obo/CHEBI_15414
T18	452-460	Chemical	denotes	adenosyl	http://purl.obolibrary.org/obo/CHEBI_33505
T19	461-471	Chemical	denotes	methionine	http://purl.obolibrary.org/obo/CHEBI_16811\|http://purl.obolibrary.org/obo/CHEBI_64558
T21	473-476	Chemical	denotes	SAM	http://purl.obolibrary.org/obo/CHEBI_15414\|http://purl.obolibrary.org/obo/CHEBI_67040

Id	Subject	Object	Predicate	Lexical cue
T10	229-371	Sentence	denotes	The most active nsp14 inhibitor identified is as potent as but particularly more specific than the broad-spectrum MTase inhibitor, sinefungin.
T11	372-536	Sentence	denotes	Molecular docking suggests that the inhibitor binds to a pocket formed by the S-adenosyl methionine (SAM) and cap RNA binding sites, conserved among SARS-CoV nsp14.