PMC:7289100 / 9410-10987
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T39 | 382-386 | Body_part | denotes | limb | http://purl.org/sig/ont/fma/fma7182 |
| T40 | 461-467 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
| T41 | 554-559 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
| T42 | 828-839 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T43 | 884-899 | Body_part | denotes | abducens nerves | http://purl.org/sig/ont/fma/fma50867 |
| T44 | 1051-1065 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
| T45 | 1360-1363 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T16 | 382-386 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
| T17 | 546-559 | Body_part | denotes | sensory nerve | http://purl.obolibrary.org/obo/UBERON_0001027 |
| T18 | 554-559 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T19 | 884-899 | Body_part | denotes | abducens nerves | http://purl.obolibrary.org/obo/UBERON_0001646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T132 | 0-3 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T135 | 64-98 | Disease | denotes | variant of Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016493 |
| T136 | 75-98 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T137 | 144-147 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T138 | 183-189 | Disease | denotes | ataxia | http://purl.obolibrary.org/obo/MONDO_0000437 |
| T139 | 206-221 | Disease | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/MONDO_0003425 |
| T140 | 247-262 | Disease | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/MONDO_0003425 |
| T141 | 286-292 | Disease | denotes | Ataxia | http://purl.obolibrary.org/obo/MONDO_0000437 |
| T142 | 397-403 | Disease | denotes | ptosis | http://purl.obolibrary.org/obo/MONDO_0000728 |
| T143 | 405-417 | Disease | denotes | facial palsy | http://purl.obolibrary.org/obo/MONDO_0001835|http://purl.obolibrary.org/obo/MONDO_0005665 |
| T145 | 412-417 | Disease | denotes | palsy | http://purl.obolibrary.org/obo/MONDO_0006496 |
| T146 | 429-434 | Disease | denotes | palsy | http://purl.obolibrary.org/obo/MONDO_0006496 |
| T147 | 481-500 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T148 | 611-614 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T149 | 694-697 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T152 | 969-984 | Disease | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/MONDO_0003425 |
| T153 | 1000-1003 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T156 | 1034-1037 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T157 | 1150-1158 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T158 | 1150-1154 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T159 | 1188-1191 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T162 | 1196-1208 | Disease | denotes | polyneuritis | http://purl.obolibrary.org/obo/MONDO_0021718 |
| T163 | 1534-1541 | Disease | denotes | anosmia | http://purl.obolibrary.org/obo/MONDO_0010528 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T88 | 7-8 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T89 | 57-58 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T90 | 172-173 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T91 | 266-267 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T92 | 382-386 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
| T93 | 461-467 | http://purl.obolibrary.org/obo/UBERON_0001630 | denotes | muscle |
| T94 | 461-467 | http://purl.obolibrary.org/obo/UBERON_0005090 | denotes | muscle |
| T95 | 461-467 | http://www.ebi.ac.uk/efo/EFO_0000801 | denotes | muscle |
| T96 | 461-467 | http://www.ebi.ac.uk/efo/EFO_0001949 | denotes | muscle |
| T97 | 554-559 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T98 | 644-645 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T99 | 893-899 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerves |
| T100 | 1092-1093 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T101 | 1480-1481 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T43 | 768-772 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
| T44 | 782-786 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
| T45 | 823-827 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
| T46 | 828-839 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T47 | 949-953 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
| T48 | 1094-1099 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T49 | 1355-1359 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T71 | 183-189 | Phenotype | denotes | ataxia | http://purl.obolibrary.org/obo/HP_0001251 |
| T72 | 191-200 | Phenotype | denotes | areflexia | http://purl.obolibrary.org/obo/HP_0001284 |
| T73 | 206-221 | Phenotype | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/HP_0000602 |
| T74 | 238-262 | Phenotype | denotes | external ophthalmoplegia | http://purl.obolibrary.org/obo/HP_0000544 |
| T75 | 286-292 | Phenotype | denotes | Ataxia | http://purl.obolibrary.org/obo/HP_0001251 |
| T76 | 340-352 | Phenotype | denotes | sensory loss | http://purl.obolibrary.org/obo/HP_0003474 |
| T77 | 382-395 | Phenotype | denotes | limb weakness | http://purl.obolibrary.org/obo/HP_0003690 |
| T78 | 397-403 | Phenotype | denotes | ptosis | http://purl.obolibrary.org/obo/HP_0000508 |
| T79 | 405-417 | Phenotype | denotes | facial palsy | http://purl.obolibrary.org/obo/HP_0010628 |
| T80 | 422-434 | Phenotype | denotes | bulbar palsy | http://purl.obolibrary.org/obo/HP_0001283 |
| T81 | 449-476 | Phenotype | denotes | generalized muscle weakness | http://purl.obolibrary.org/obo/HP_0003324 |
| T82 | 481-500 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T83 | 969-984 | Phenotype | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/HP_0000602 |
| T84 | 1196-1208 | Phenotype | denotes | polyneuritis | http://purl.obolibrary.org/obo/HP_0031003 |
| T85 | 1534-1541 | Phenotype | denotes | anosmia | http://purl.obolibrary.org/obo/HP_0000458 |
| T86 | 1546-1553 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 560-577 | http://purl.obolibrary.org/obo/GO_0001508 | denotes | action potentials |
| T4 | 598-604 | http://purl.obolibrary.org/obo/GO_0060004 | denotes | reflex |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T1 | 768-772 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T2 | 777-786 | GlycoEpitope | denotes | anti-GD1b | http://www.glycoepitope.jp/epitopes/AN0403 |
| T3 | 782-786 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T4 | 823-827 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T5 | 949-953 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T6 | 1350-1359 | GlycoEpitope | denotes | anti-GD1b | http://www.glycoepitope.jp/epitopes/AN0403 |
| T7 | 1355-1359 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T58 | 0-148 | Sentence | denotes | MFS is a rare, acquired disease that is considered to be a mild variant of Guillain-Barré syndrome, and is observed in about 5% of all cases of GBS. |
| T59 | 149-222 | Sentence | denotes | It is characterized by a triad of ataxia, areflexia, and ophthalmoplegia. |
| T60 | 223-285 | Sentence | denotes | Acute onset of external ophthalmoplegia is a cardinal feature. |
| T61 | 286-353 | Sentence | denotes | Ataxia tends to be out of proportion to the degree of sensory loss. |
| T62 | 354-435 | Sentence | denotes | Patients may also have mild limb weakness, ptosis, facial palsy, or bulbar palsy. |
| T63 | 436-513 | Sentence | denotes | Occasionally generalized muscle weakness and respiratory failure may develop. |
| T64 | 514-605 | Sentence | denotes | Patients have reduced or absent sensory nerve action potentials and absent tibial H reflex. |
| T65 | 606-660 | Sentence | denotes | Like GBS, symptoms may be preceded by a viral illness. |
| T66 | 661-798 | Sentence | denotes | The majority of individuals with MFS have unique antibodies that characterize the disorder, which are Anti-GQ1b and anti-GD1b antibodies. |
| T67 | 799-985 | Sentence | denotes | Dense concentrations of GQ1b ganglioside are found in the oculomotor, trochlear, and abducens nerves, which may explain the relationship between anti-GQ1b antibodies and ophthalmoplegia. |
| T68 | 986-1091 | Sentence | denotes | Treatment for MFS is identical to treatment for GBS: intravenous immunoglobulin (IVIG) or plasmapheresis. |
| T69 | 1092-1232 | Sentence | denotes | A group from Spain reported of two patients infected with SARS-CoV-2 who acutely presented with MFS and polyneuritis cranialis respectively. |
| T70 | 1233-1296 | Sentence | denotes | Both patients presented with the typical neurological symptoms. |
| T71 | 1297-1443 | Sentence | denotes | One of the two patients was found to be positive for anti-GD1b-IgG antibodies and was treated with IVIG and the second patient with acetaminophen. |
| T72 | 1444-1577 | Sentence | denotes | Two weeks later, both patients made a complete neurological recovery, except for residual anosmia and ageusia in the first case [39]. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T169 | 382-386 | UBERON:0002101 | denotes | limb |
| T170 | 405-411 | UBERON:0001456 | denotes | facial |
| T171 | 481-492 | UBERON:0001004 | denotes | respiratory |
| T172 | 554-559 | UBERON:0001027 | denotes | nerve |
| T173 | 589-595 | UBERON:0001323 | denotes | tibial |
| T174 | 598-604 | GO:0060004 | denotes | reflex |
| T175 | 646-651 | NCBITaxon:10239 | denotes | viral |
| T176 | 677-688 | NCBITaxon:1 | denotes | individuals |
| T177 | 710-720 | GO:0042571 | denotes | antibodies |
| T178 | 787-797 | GO:0042571 | denotes | antibodies |
| T179 | 828-839 | CHEBI:5386;CHEBI:5386 | denotes | ganglioside |
| T180 | 869-878 | UBERON:0001675 | denotes | trochlear |
| T181 | 884-899 | UBERON:0001646 | denotes | abducens nerves |
| T182 | 954-964 | GO:0042571 | denotes | antibodies |
| T183 | 1051-1065 | GO:0019814 | denotes | immunoglobulin |
| T184 | 1067-1071 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T185 | 1150-1160 | SP_7 | denotes | SARS-CoV-2 |
| T186 | 1274-1286 | UBERON:0001016 | denotes | neurological |
| T187 | 1360-1374 | GO:0071743 | denotes | IgG antibodies |
| T188 | 1396-1400 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T189 | 1429-1442 | CHEBI:15344;CHEBI:15344 | denotes | acetaminophen |
| T190 | 1491-1503 | UBERON:0001016 | denotes | neurological |
| T75928 | 382-386 | UBERON:0002101 | denotes | limb |
| T83737 | 405-411 | UBERON:0001456 | denotes | facial |
| T76354 | 481-492 | UBERON:0001004 | denotes | respiratory |
| T62533 | 554-559 | UBERON:0001027 | denotes | nerve |
| T74267 | 589-595 | UBERON:0001323 | denotes | tibial |
| T81522 | 598-604 | GO:0060004 | denotes | reflex |
| T30006 | 646-651 | NCBITaxon:10239 | denotes | viral |
| T10751 | 677-688 | NCBITaxon:1 | denotes | individuals |
| T25513 | 710-720 | GO:0042571 | denotes | antibodies |
| T21503 | 787-797 | GO:0042571 | denotes | antibodies |
| T49701 | 828-839 | CHEBI:5386;CHEBI:5386 | denotes | ganglioside |
| T65826 | 869-878 | UBERON:0001675 | denotes | trochlear |
| T83465 | 884-899 | UBERON:0001646 | denotes | abducens nerves |
| T82807 | 954-964 | GO:0042571 | denotes | antibodies |
| T22659 | 1051-1065 | GO:0019814 | denotes | immunoglobulin |
| T7525 | 1067-1071 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T73937 | 1150-1160 | SP_7 | denotes | SARS-CoV-2 |
| T94179 | 1274-1286 | UBERON:0001016 | denotes | neurological |
| T99822 | 1360-1374 | GO:0071743 | denotes | IgG antibodies |
| T78981 | 1396-1400 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T92920 | 1429-1442 | CHEBI:15344;CHEBI:15344 | denotes | acetaminophen |
| T34859 | 1491-1503 | UBERON:0001016 | denotes | neurological |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 349 | 354-362 | Species | denotes | Patients | Tax:9606 |
| 350 | 514-522 | Species | denotes | Patients | Tax:9606 |
| 351 | 1127-1135 | Species | denotes | patients | Tax:9606 |
| 352 | 1150-1160 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 353 | 1238-1246 | Species | denotes | patients | Tax:9606 |
| 354 | 1312-1320 | Species | denotes | patients | Tax:9606 |
| 355 | 1416-1423 | Species | denotes | patient | Tax:9606 |
| 356 | 1466-1474 | Species | denotes | patients | Tax:9606 |
| 357 | 144-147 | Chemical | denotes | GBS | |
| 358 | 611-614 | Chemical | denotes | GBS | |
| 359 | 828-839 | Chemical | denotes | ganglioside | MESH:D005732 |
| 360 | 1034-1037 | Chemical | denotes | GBS | |
| 361 | 1429-1442 | Chemical | denotes | acetaminophen | MESH:D000082 |
| 362 | 0-3 | Disease | denotes | MFS | MESH:D008382 |
| 363 | 183-189 | Disease | denotes | ataxia | MESH:D001259 |
| 364 | 191-200 | Disease | denotes | areflexia | MESH:D000071699 |
| 365 | 206-221 | Disease | denotes | ophthalmoplegia | MESH:D009886 |
| 366 | 238-262 | Disease | denotes | external ophthalmoplegia | MESH:D009886 |
| 367 | 286-292 | Disease | denotes | Ataxia | MESH:D001259 |
| 368 | 340-352 | Disease | denotes | sensory loss | MESH:D012678 |
| 369 | 382-395 | Disease | denotes | limb weakness | MESH:D018908 |
| 370 | 397-403 | Disease | denotes | ptosis | MESH:C564553 |
| 371 | 405-417 | Disease | denotes | facial palsy | MESH:D005158 |
| 372 | 422-434 | Disease | denotes | bulbar palsy | MESH:D010244 |
| 373 | 461-476 | Disease | denotes | muscle weakness | MESH:D018908 |
| 374 | 481-500 | Disease | denotes | respiratory failure | MESH:D012131 |
| 375 | 646-659 | Disease | denotes | viral illness | |
| 376 | 694-697 | Disease | denotes | MFS | MESH:D008382 |
| 377 | 969-984 | Disease | denotes | ophthalmoplegia | MESH:D009886 |
| 378 | 1000-1003 | Disease | denotes | MFS | MESH:D008382 |
| 379 | 1136-1144 | Disease | denotes | infected | MESH:D007239 |
| 380 | 1188-1191 | Disease | denotes | MFS | MESH:D008382 |
| 381 | 1196-1208 | Disease | denotes | polyneuritis | MESH:D009443 |
| 382 | 1274-1295 | Disease | denotes | neurological symptoms | MESH:D009422 |
| 383 | 1534-1553 | Disease | denotes | anosmia and ageusia | MESH:D000370 |