PMC:7289100 / 9356-10987
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T39 | 436-440 | Body_part | denotes | limb | http://purl.org/sig/ont/fma/fma7182 |
| T40 | 515-521 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
| T41 | 608-613 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
| T42 | 882-893 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T43 | 938-953 | Body_part | denotes | abducens nerves | http://purl.org/sig/ont/fma/fma50867 |
| T44 | 1105-1119 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
| T45 | 1414-1417 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T16 | 436-440 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
| T17 | 600-613 | Body_part | denotes | sensory nerve | http://purl.obolibrary.org/obo/UBERON_0001027 |
| T18 | 608-613 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T19 | 938-953 | Body_part | denotes | abducens nerves | http://purl.obolibrary.org/obo/UBERON_0001646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T127 | 3-25 | Disease | denotes | Miller Fisher syndrome | http://purl.obolibrary.org/obo/MONDO_0005851 |
| T128 | 27-30 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T131 | 45-53 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T132 | 54-57 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T135 | 118-152 | Disease | denotes | variant of Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016493 |
| T136 | 129-152 | Disease | denotes | Guillain-Barré syndrome | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T137 | 198-201 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T138 | 237-243 | Disease | denotes | ataxia | http://purl.obolibrary.org/obo/MONDO_0000437 |
| T139 | 260-275 | Disease | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/MONDO_0003425 |
| T140 | 301-316 | Disease | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/MONDO_0003425 |
| T141 | 340-346 | Disease | denotes | Ataxia | http://purl.obolibrary.org/obo/MONDO_0000437 |
| T142 | 451-457 | Disease | denotes | ptosis | http://purl.obolibrary.org/obo/MONDO_0000728 |
| T143 | 459-471 | Disease | denotes | facial palsy | http://purl.obolibrary.org/obo/MONDO_0001835|http://purl.obolibrary.org/obo/MONDO_0005665 |
| T145 | 466-471 | Disease | denotes | palsy | http://purl.obolibrary.org/obo/MONDO_0006496 |
| T146 | 483-488 | Disease | denotes | palsy | http://purl.obolibrary.org/obo/MONDO_0006496 |
| T147 | 535-554 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T148 | 665-668 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T149 | 748-751 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T152 | 1023-1038 | Disease | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/MONDO_0003425 |
| T153 | 1054-1057 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T156 | 1088-1091 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T157 | 1204-1212 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T158 | 1204-1208 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T159 | 1242-1245 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T162 | 1250-1262 | Disease | denotes | polyneuritis | http://purl.obolibrary.org/obo/MONDO_0021718 |
| T163 | 1588-1595 | Disease | denotes | anosmia | http://purl.obolibrary.org/obo/MONDO_0010528 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T88 | 61-62 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T89 | 111-112 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T90 | 226-227 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T91 | 320-321 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T92 | 436-440 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
| T93 | 515-521 | http://purl.obolibrary.org/obo/UBERON_0001630 | denotes | muscle |
| T94 | 515-521 | http://purl.obolibrary.org/obo/UBERON_0005090 | denotes | muscle |
| T95 | 515-521 | http://www.ebi.ac.uk/efo/EFO_0000801 | denotes | muscle |
| T96 | 515-521 | http://www.ebi.ac.uk/efo/EFO_0001949 | denotes | muscle |
| T97 | 608-613 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T98 | 698-699 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T99 | 947-953 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerves |
| T100 | 1146-1147 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T101 | 1534-1535 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T43 | 822-826 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
| T44 | 836-840 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
| T45 | 877-881 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
| T46 | 882-893 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T47 | 1003-1007 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
| T48 | 1148-1153 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T49 | 1409-1413 | Chemical | denotes | GD1b | http://purl.obolibrary.org/obo/CHEBI_28175 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T71 | 237-243 | Phenotype | denotes | ataxia | http://purl.obolibrary.org/obo/HP_0001251 |
| T72 | 245-254 | Phenotype | denotes | areflexia | http://purl.obolibrary.org/obo/HP_0001284 |
| T73 | 260-275 | Phenotype | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/HP_0000602 |
| T74 | 292-316 | Phenotype | denotes | external ophthalmoplegia | http://purl.obolibrary.org/obo/HP_0000544 |
| T75 | 340-346 | Phenotype | denotes | Ataxia | http://purl.obolibrary.org/obo/HP_0001251 |
| T76 | 394-406 | Phenotype | denotes | sensory loss | http://purl.obolibrary.org/obo/HP_0003474 |
| T77 | 436-449 | Phenotype | denotes | limb weakness | http://purl.obolibrary.org/obo/HP_0003690 |
| T78 | 451-457 | Phenotype | denotes | ptosis | http://purl.obolibrary.org/obo/HP_0000508 |
| T79 | 459-471 | Phenotype | denotes | facial palsy | http://purl.obolibrary.org/obo/HP_0010628 |
| T80 | 476-488 | Phenotype | denotes | bulbar palsy | http://purl.obolibrary.org/obo/HP_0001283 |
| T81 | 503-530 | Phenotype | denotes | generalized muscle weakness | http://purl.obolibrary.org/obo/HP_0003324 |
| T82 | 535-554 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T83 | 1023-1038 | Phenotype | denotes | ophthalmoplegia | http://purl.obolibrary.org/obo/HP_0000602 |
| T84 | 1250-1262 | Phenotype | denotes | polyneuritis | http://purl.obolibrary.org/obo/HP_0031003 |
| T85 | 1588-1595 | Phenotype | denotes | anosmia | http://purl.obolibrary.org/obo/HP_0000458 |
| T86 | 1600-1607 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 614-631 | http://purl.obolibrary.org/obo/GO_0001508 | denotes | action potentials |
| T4 | 652-658 | http://purl.obolibrary.org/obo/GO_0060004 | denotes | reflex |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T1 | 822-826 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T2 | 831-840 | GlycoEpitope | denotes | anti-GD1b | http://www.glycoepitope.jp/epitopes/AN0403 |
| T3 | 836-840 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T4 | 877-881 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T5 | 1003-1007 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T6 | 1404-1413 | GlycoEpitope | denotes | anti-GD1b | http://www.glycoepitope.jp/epitopes/AN0403 |
| T7 | 1409-1413 | GlycoEpitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T57 | 0-53 | Sentence | denotes | 5 Miller Fisher syndrome (MFS) secondary to COVID-19 |
| T58 | 54-202 | Sentence | denotes | MFS is a rare, acquired disease that is considered to be a mild variant of Guillain-Barré syndrome, and is observed in about 5% of all cases of GBS. |
| T59 | 203-276 | Sentence | denotes | It is characterized by a triad of ataxia, areflexia, and ophthalmoplegia. |
| T60 | 277-339 | Sentence | denotes | Acute onset of external ophthalmoplegia is a cardinal feature. |
| T61 | 340-407 | Sentence | denotes | Ataxia tends to be out of proportion to the degree of sensory loss. |
| T62 | 408-489 | Sentence | denotes | Patients may also have mild limb weakness, ptosis, facial palsy, or bulbar palsy. |
| T63 | 490-567 | Sentence | denotes | Occasionally generalized muscle weakness and respiratory failure may develop. |
| T64 | 568-659 | Sentence | denotes | Patients have reduced or absent sensory nerve action potentials and absent tibial H reflex. |
| T65 | 660-714 | Sentence | denotes | Like GBS, symptoms may be preceded by a viral illness. |
| T66 | 715-852 | Sentence | denotes | The majority of individuals with MFS have unique antibodies that characterize the disorder, which are Anti-GQ1b and anti-GD1b antibodies. |
| T67 | 853-1039 | Sentence | denotes | Dense concentrations of GQ1b ganglioside are found in the oculomotor, trochlear, and abducens nerves, which may explain the relationship between anti-GQ1b antibodies and ophthalmoplegia. |
| T68 | 1040-1145 | Sentence | denotes | Treatment for MFS is identical to treatment for GBS: intravenous immunoglobulin (IVIG) or plasmapheresis. |
| T69 | 1146-1286 | Sentence | denotes | A group from Spain reported of two patients infected with SARS-CoV-2 who acutely presented with MFS and polyneuritis cranialis respectively. |
| T70 | 1287-1350 | Sentence | denotes | Both patients presented with the typical neurological symptoms. |
| T71 | 1351-1497 | Sentence | denotes | One of the two patients was found to be positive for anti-GD1b-IgG antibodies and was treated with IVIG and the second patient with acetaminophen. |
| T72 | 1498-1631 | Sentence | denotes | Two weeks later, both patients made a complete neurological recovery, except for residual anosmia and ageusia in the first case [39]. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T168 | 45-53 | SP_7 | denotes | COVID-19 |
| T169 | 436-440 | UBERON:0002101 | denotes | limb |
| T170 | 459-465 | UBERON:0001456 | denotes | facial |
| T171 | 535-546 | UBERON:0001004 | denotes | respiratory |
| T172 | 608-613 | UBERON:0001027 | denotes | nerve |
| T173 | 643-649 | UBERON:0001323 | denotes | tibial |
| T174 | 652-658 | GO:0060004 | denotes | reflex |
| T175 | 700-705 | NCBITaxon:10239 | denotes | viral |
| T176 | 731-742 | NCBITaxon:1 | denotes | individuals |
| T177 | 764-774 | GO:0042571 | denotes | antibodies |
| T178 | 841-851 | GO:0042571 | denotes | antibodies |
| T179 | 882-893 | CHEBI:5386;CHEBI:5386 | denotes | ganglioside |
| T180 | 923-932 | UBERON:0001675 | denotes | trochlear |
| T181 | 938-953 | UBERON:0001646 | denotes | abducens nerves |
| T182 | 1008-1018 | GO:0042571 | denotes | antibodies |
| T183 | 1105-1119 | GO:0019814 | denotes | immunoglobulin |
| T184 | 1121-1125 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T185 | 1204-1214 | SP_7 | denotes | SARS-CoV-2 |
| T186 | 1328-1340 | UBERON:0001016 | denotes | neurological |
| T187 | 1414-1428 | GO:0071743 | denotes | IgG antibodies |
| T188 | 1450-1454 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T189 | 1483-1496 | CHEBI:15344;CHEBI:15344 | denotes | acetaminophen |
| T190 | 1545-1557 | UBERON:0001016 | denotes | neurological |
| T97252 | 45-53 | SP_7 | denotes | COVID-19 |
| T75928 | 436-440 | UBERON:0002101 | denotes | limb |
| T83737 | 459-465 | UBERON:0001456 | denotes | facial |
| T76354 | 535-546 | UBERON:0001004 | denotes | respiratory |
| T62533 | 608-613 | UBERON:0001027 | denotes | nerve |
| T74267 | 643-649 | UBERON:0001323 | denotes | tibial |
| T81522 | 652-658 | GO:0060004 | denotes | reflex |
| T30006 | 700-705 | NCBITaxon:10239 | denotes | viral |
| T10751 | 731-742 | NCBITaxon:1 | denotes | individuals |
| T25513 | 764-774 | GO:0042571 | denotes | antibodies |
| T21503 | 841-851 | GO:0042571 | denotes | antibodies |
| T49701 | 882-893 | CHEBI:5386;CHEBI:5386 | denotes | ganglioside |
| T65826 | 923-932 | UBERON:0001675 | denotes | trochlear |
| T83465 | 938-953 | UBERON:0001646 | denotes | abducens nerves |
| T82807 | 1008-1018 | GO:0042571 | denotes | antibodies |
| T22659 | 1105-1119 | GO:0019814 | denotes | immunoglobulin |
| T7525 | 1121-1125 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T73937 | 1204-1214 | SP_7 | denotes | SARS-CoV-2 |
| T94179 | 1328-1340 | UBERON:0001016 | denotes | neurological |
| T99822 | 1414-1428 | GO:0071743 | denotes | IgG antibodies |
| T78981 | 1450-1454 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T92920 | 1483-1496 | CHEBI:15344;CHEBI:15344 | denotes | acetaminophen |
| T34859 | 1545-1557 | UBERON:0001016 | denotes | neurological |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 312 | 27-30 | Disease | denotes | MFS | MESH:D008382 |
| 313 | 45-53 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 349 | 408-416 | Species | denotes | Patients | Tax:9606 |
| 350 | 568-576 | Species | denotes | Patients | Tax:9606 |
| 351 | 1181-1189 | Species | denotes | patients | Tax:9606 |
| 352 | 1204-1214 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 353 | 1292-1300 | Species | denotes | patients | Tax:9606 |
| 354 | 1366-1374 | Species | denotes | patients | Tax:9606 |
| 355 | 1470-1477 | Species | denotes | patient | Tax:9606 |
| 356 | 1520-1528 | Species | denotes | patients | Tax:9606 |
| 357 | 198-201 | Chemical | denotes | GBS | |
| 358 | 665-668 | Chemical | denotes | GBS | |
| 359 | 882-893 | Chemical | denotes | ganglioside | MESH:D005732 |
| 360 | 1088-1091 | Chemical | denotes | GBS | |
| 361 | 1483-1496 | Chemical | denotes | acetaminophen | MESH:D000082 |
| 362 | 54-57 | Disease | denotes | MFS | MESH:D008382 |
| 363 | 237-243 | Disease | denotes | ataxia | MESH:D001259 |
| 364 | 245-254 | Disease | denotes | areflexia | MESH:D000071699 |
| 365 | 260-275 | Disease | denotes | ophthalmoplegia | MESH:D009886 |
| 366 | 292-316 | Disease | denotes | external ophthalmoplegia | MESH:D009886 |
| 367 | 340-346 | Disease | denotes | Ataxia | MESH:D001259 |
| 368 | 394-406 | Disease | denotes | sensory loss | MESH:D012678 |
| 369 | 436-449 | Disease | denotes | limb weakness | MESH:D018908 |
| 370 | 451-457 | Disease | denotes | ptosis | MESH:C564553 |
| 371 | 459-471 | Disease | denotes | facial palsy | MESH:D005158 |
| 372 | 476-488 | Disease | denotes | bulbar palsy | MESH:D010244 |
| 373 | 515-530 | Disease | denotes | muscle weakness | MESH:D018908 |
| 374 | 535-554 | Disease | denotes | respiratory failure | MESH:D012131 |
| 375 | 700-713 | Disease | denotes | viral illness | |
| 376 | 748-751 | Disease | denotes | MFS | MESH:D008382 |
| 377 | 1023-1038 | Disease | denotes | ophthalmoplegia | MESH:D009886 |
| 378 | 1054-1057 | Disease | denotes | MFS | MESH:D008382 |
| 379 | 1190-1198 | Disease | denotes | infected | MESH:D007239 |
| 380 | 1242-1245 | Disease | denotes | MFS | MESH:D008382 |
| 381 | 1250-1262 | Disease | denotes | polyneuritis | MESH:D009443 |
| 382 | 1328-1349 | Disease | denotes | neurological symptoms | MESH:D009422 |
| 383 | 1588-1607 | Disease | denotes | anosmia and ageusia | MESH:D000370 |