PMC:7289100 / 7205-9354
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T29 | 178-191 | Body_part | denotes | cranial nerve | http://purl.org/sig/ont/fma/fma5865 |
| T30 | 290-300 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
| T31 | 423-426 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T32 | 636-649 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
| T33 | 658-670 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T34 | 678-703 | Body_part | denotes | peripheral nervous system | http://purl.org/sig/ont/fma/fma9903 |
| T35 | 886-898 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T36 | 1158-1168 | Body_part | denotes | lower-limb | http://purl.org/sig/ont/fma/fma7184 |
| T37 | 1426-1437 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T38 | 1560-1566 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T10 | 178-191 | Body_part | denotes | cranial nerve | http://purl.obolibrary.org/obo/UBERON_0001785 |
| T11 | 186-191 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
| T12 | 636-649 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
| T13 | 678-703 | Body_part | denotes | peripheral nervous system | http://purl.obolibrary.org/obo/UBERON_0000010 |
| T14 | 689-703 | Body_part | denotes | nervous system | http://purl.obolibrary.org/obo/UBERON_0001016 |
| T15 | 1164-1168 | Body_part | denotes | limb | http://purl.obolibrary.org/obo/UBERON_0002101 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T101 | 28-31 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T102 | 46-54 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T103 | 55-58 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T104 | 301-311 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T105 | 350-360 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T106 | 369-378 | Disease | denotes | Influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T107 | 380-389 | Disease | denotes | Chlamydia | http://purl.obolibrary.org/obo/MONDO_0005701 |
| T108 | 396-405 | Disease | denotes | varicella | http://purl.obolibrary.org/obo/MONDO_0005700 |
| T109 | 407-412 | Disease | denotes | mumps | http://purl.obolibrary.org/obo/MONDO_0000989 |
| T110 | 414-421 | Disease | denotes | rubella | http://purl.obolibrary.org/obo/MONDO_0004656 |
| T111 | 428-433 | Disease | denotes | Polio | http://purl.obolibrary.org/obo/MONDO_0017373 |
| T112 | 435-446 | Disease | denotes | Hepatitis E | http://purl.obolibrary.org/obo/MONDO_0005788 |
| T113 | 435-444 | Disease | denotes | Hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T114 | 448-456 | Disease | denotes | Borrelia | http://purl.obolibrary.org/obo/MONDO_0019632 |
| T115 | 458-478 | Disease | denotes | Mycoplasma pneumonia | http://purl.obolibrary.org/obo/MONDO_0005867 |
| T116 | 469-478 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T117 | 512-515 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T118 | 603-622 | Disease | denotes | autoimmune disorder | http://purl.obolibrary.org/obo/MONDO_0007179 |
| T119 | 743-746 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T120 | 772-781 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T121 | 1239-1245 | Disease | denotes | ataxia | http://purl.obolibrary.org/obo/MONDO_0000437 |
| T122 | 1300-1311 | Disease | denotes | tetraplegia | http://purl.obolibrary.org/obo/MONDO_0001590 |
| T123 | 1902-1905 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T124 | 2005-2008 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T125 | 2044-2052 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T126 | 2044-2048 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T70 | 62-63 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T71 | 108-113 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limbs |
| T72 | 186-191 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T73 | 290-300 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
| T74 | 290-300 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
| T75 | 636-649 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T76 | 678-703 | http://purl.obolibrary.org/obo/UBERON_0000010 | denotes | peripheral nervous system |
| T77 | 678-703 | http://www.ebi.ac.uk/efo/EFO_0000891 | denotes | peripheral nervous system |
| T78 | 913-914 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T79 | 1164-1168 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limb |
| T80 | 1325-1326 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T81 | 1337-1339 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T82 | 1560-1566 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T83 | 1615-1616 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T84 | 1629-1633 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
| T85 | 1629-1633 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
| T86 | 1743-1744 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T87 | 1996-1997 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T37 | 658-670 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T38 | 886-898 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T39 | 1426-1437 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T40 | 1629-1633 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
| T41 | 1843-1861 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T42 | 1863-1872 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T53 | 114-123 | Phenotype | denotes | paralysis | http://purl.obolibrary.org/obo/HP_0003470 |
| T54 | 136-145 | Phenotype | denotes | areflexia | http://purl.obolibrary.org/obo/HP_0001284 |
| T55 | 149-161 | Phenotype | denotes | hyporeflexia | http://purl.obolibrary.org/obo/HP_0001265 |
| T56 | 178-203 | Phenotype | denotes | cranial nerve involvement | http://purl.obolibrary.org/obo/HP_0001291 |
| T57 | 435-444 | Phenotype | denotes | Hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T58 | 469-478 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T59 | 603-622 | Phenotype | denotes | autoimmune disorder | http://purl.obolibrary.org/obo/HP_0002960 |
| T60 | 1158-1177 | Phenotype | denotes | lower-limb weakness | http://purl.obolibrary.org/obo/HP_0007340 |
| T61 | 1182-1193 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
| T62 | 1211-1226 | Phenotype | denotes | facial diplegia | http://purl.obolibrary.org/obo/HP_0001349 |
| T63 | 1239-1245 | Phenotype | denotes | ataxia | http://purl.obolibrary.org/obo/HP_0001251 |
| T64 | 1250-1261 | Phenotype | denotes | paresthesia | http://purl.obolibrary.org/obo/HP_0003401 |
| T65 | 1284-1296 | Phenotype | denotes | tetraparesis | http://purl.obolibrary.org/obo/HP_0002273 |
| T66 | 1300-1311 | Phenotype | denotes | tetraplegia | http://purl.obolibrary.org/obo/HP_0002445 |
| T67 | 1712-1725 | Phenotype | denotes | quadriparesis | http://purl.obolibrary.org/obo/HP_0002273 |
| T68 | 1756-1761 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T69 | 1763-1768 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T70 | 1773-1780 | Phenotype | denotes | dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 1567-1575 | http://purl.obolibrary.org/obo/GO_0015297 | denotes | exchange |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T37 | 0-54 | Sentence | denotes | 4 Guillian-Barrė syndrome (GBS) secondary to COVID-19 |
| T38 | 55-242 | Sentence | denotes | GBS is a progressive, ascending, symmetrical flaccid limbs paralysis, along with areflexia or hyporeflexia with or without cranial nerve involvement which can progress over days to weeks. |
| T39 | 243-328 | Sentence | denotes | The disease may be triggered by respiratory or intestinal infections or vaccinations. |
| T40 | 329-511 | Sentence | denotes | The known triggering infections include Influenza; Chlamydia; CMV; varicella; mumps; rubella; HIV; Polio; Hepatitis E; Borrelia; Mycoplasma pneumonia as well as Campilobacter Jejuni. |
| T41 | 512-712 | Sentence | denotes | GBS is an immune-mediated disorder with molecular mimicry playing an important role in its autoimmune disorder in which the immune system attacks gangliosides on the peripheral nervous system [34,35]. |
| T42 | 713-790 | Sentence | denotes | There are so far 2 reports of GBS associated with Covid-19 infection [36,37]. |
| T43 | 791-899 | Sentence | denotes | It is yet unclear whether Covid-19 induces the production of antibodies against these specific gangliosides. |
| T44 | 900-1035 | Sentence | denotes | The first is a report of five out of 1200 patients hospitalized between February 28th and March 21st, 2020 in Northern Italy hospitals. |
| T45 | 1036-1126 | Sentence | denotes | The onset of neurological symptoms began 7–10 days after the initial respiratory symptoms. |
| T46 | 1127-1262 | Sentence | denotes | Four out of the 5 patients had lower-limb weakness and paresthesia and one was with facial diplegia followed by ataxia and paresthesia. |
| T47 | 1263-1373 | Sentence | denotes | Generalized, flaccid tetraparesis or tetraplegia evolved over a period of 36 h to 4 days in 4 of the patients. |
| T48 | 1374-1420 | Sentence | denotes | Three of them required mechanical ventilation. |
| T49 | 1421-1482 | Sentence | denotes | Anti-ganglioside antibodies were either negative or not done. |
| T50 | 1483-1576 | Sentence | denotes | All patients received IVIG (1 of then required 2 cycles) and one had started plasma exchange. |
| T51 | 1577-1781 | Sentence | denotes | The second report from Iran describes a 65 year old male patient admitted to hospital because of acute progressive symmetric ascending quadriparesis, two weeks after a history of cough, fever and dyspnea. |
| T52 | 1782-1815 | Sentence | denotes | Covid-19 was diagnosed by RT-PCR. |
| T53 | 1816-1901 | Sentence | denotes | The patient was treated by hydroxychloroquine, Lopinavir/Ritonavir, and Azithromycin. |
| T54 | 1902-1927 | Sentence | denotes | GBS was confirmed by EMG. |
| T55 | 1928-1971 | Sentence | denotes | The patient was treated by IVIG for 5 days. |
| T56 | 1972-2149 | Sentence | denotes | Another early report of a single GBS patient came from China during the SARS-CoV-2 epidemic, although there is some concern regarding the causality in this particular case [38]. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T134 | 46-54 | SP_7 | denotes | COVID-19 |
| T135 | 108-113 | UBERON:0002101 | denotes | limbs |
| T136 | 178-191 | UBERON:0001785 | denotes | cranial nerve |
| T137 | 275-286 | UBERON:0001004 | denotes | respiratory |
| T138 | 290-300 | UBERON:0000160 | denotes | intestinal |
| T139 | 380-389 | NCBITaxon:810 | denotes | Chlamydia |
| T140 | 391-394 | NCBITaxon:10358 | denotes | CMV |
| T141 | 414-421 | NCBITaxon:31033 | denotes | rubella |
| T142 | 448-456 | NCBITaxon:138 | denotes | Borrelia |
| T143 | 458-468 | NCBITaxon:2093 | denotes | Mycoplasma |
| T144 | 522-528 | UBERON:0002405 | denotes | immune |
| T145 | 603-613 | UBERON:0002405 | denotes | autoimmune |
| T146 | 636-649 | UBERON:0002405 | denotes | immune system |
| T147 | 658-670 | CHEBI:16856;CHEBI:16856 | denotes | gangliosides |
| T148 | 678-703 | UBERON:0000010 | denotes | peripheral nervous system |
| T149 | 763-771 | SP_7 | denotes | Covid-19 |
| T150 | 817-825 | SP_7 | denotes | Covid-19 |
| T151 | 852-862 | GO:0042571 | denotes | antibodies |
| T152 | 886-898 | CHEBI:28892;CHEBI:28892 | denotes | gangliosides |
| T153 | 1049-1061 | UBERON:0001016 | denotes | neurological |
| T154 | 1105-1116 | UBERON:0001004 | denotes | respiratory |
| T155 | 1164-1168 | UBERON:0002103 | denotes | limb |
| T156 | 1211-1217 | UBERON:0001456 | denotes | facial |
| T157 | 1426-1437 | CHEBI:28892;CHEBI:28892 | denotes | ganglioside |
| T158 | 1438-1448 | GO:0042571 | denotes | antibodies |
| T159 | 1505-1509 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T160 | 1560-1566 | UBERON:0001969;GO:0030168 | denotes | plasma |
| T161 | 1782-1790 | SP_7 | denotes | Covid-19 |
| T162 | 1843-1861 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T163 | 1863-1872 | DG_23 | denotes | Lopinavir |
| T164 | 1873-1882 | DG_30 | denotes | Ritonavir |
| T165 | 1888-1900 | CHEBI:28619;DG_6;CHEBI:28619 | denotes | Azithromycin |
| T166 | 1955-1959 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T167 | 2044-2054 | SP_7 | denotes | SARS-CoV-2 |
| T20708 | 46-54 | SP_7 | denotes | COVID-19 |
| T61735 | 108-113 | UBERON:0002101 | denotes | limbs |
| T34156 | 178-191 | UBERON:0001785 | denotes | cranial nerve |
| T56150 | 275-286 | UBERON:0001004 | denotes | respiratory |
| T26041 | 290-300 | UBERON:0000160 | denotes | intestinal |
| T5537 | 380-389 | NCBITaxon:810 | denotes | Chlamydia |
| T47372 | 391-394 | NCBITaxon:10358 | denotes | CMV |
| T86481 | 414-421 | NCBITaxon:31033 | denotes | rubella |
| T32318 | 448-456 | NCBITaxon:138 | denotes | Borrelia |
| T34988 | 458-468 | NCBITaxon:2093 | denotes | Mycoplasma |
| T84577 | 522-528 | UBERON:0002405 | denotes | immune |
| T7940 | 603-613 | UBERON:0002405 | denotes | autoimmune |
| T69529 | 636-649 | UBERON:0002405 | denotes | immune system |
| T63033 | 658-670 | CHEBI:16856;CHEBI:16856 | denotes | gangliosides |
| T86657 | 678-703 | UBERON:0000010 | denotes | peripheral nervous system |
| T10423 | 763-771 | SP_7 | denotes | Covid-19 |
| T75493 | 817-825 | SP_7 | denotes | Covid-19 |
| T35763 | 852-862 | GO:0042571 | denotes | antibodies |
| T7962 | 886-898 | CHEBI:28892;CHEBI:28892 | denotes | gangliosides |
| T34902 | 1049-1061 | UBERON:0001016 | denotes | neurological |
| T98751 | 1105-1116 | UBERON:0001004 | denotes | respiratory |
| T41824 | 1164-1168 | UBERON:0002103 | denotes | limb |
| T29107 | 1211-1217 | UBERON:0001456 | denotes | facial |
| T58767 | 1426-1437 | CHEBI:28892;CHEBI:28892 | denotes | ganglioside |
| T17970 | 1438-1448 | GO:0042571 | denotes | antibodies |
| T23017 | 1505-1509 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T59182 | 1560-1566 | UBERON:0001969;GO:0030168 | denotes | plasma |
| T99347 | 1782-1790 | SP_7 | denotes | Covid-19 |
| T13154 | 1843-1861 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T39287 | 1863-1872 | DG_23 | denotes | Lopinavir |
| T73644 | 1873-1882 | DG_30 | denotes | Ritonavir |
| T88345 | 1888-1900 | CHEBI:28619;DG_6;CHEBI:28619 | denotes | Azithromycin |
| T35837 | 1955-1959 | CHEBI:42098;CHEBI:42098 | denotes | IVIG |
| T3374 | 2044-2054 | SP_7 | denotes | SARS-CoV-2 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 223 | 46-54 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 267 | 942-950 | Species | denotes | patients | Tax:9606 |
| 268 | 1145-1153 | Species | denotes | patients | Tax:9606 |
| 269 | 1364-1372 | Species | denotes | patients | Tax:9606 |
| 270 | 1487-1495 | Species | denotes | patients | Tax:9606 |
| 271 | 1634-1641 | Species | denotes | patient | Tax:9606 |
| 272 | 1820-1827 | Species | denotes | patient | Tax:9606 |
| 273 | 1932-1939 | Species | denotes | patient | Tax:9606 |
| 274 | 2009-2016 | Species | denotes | patient | Tax:9606 |
| 275 | 2044-2054 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 276 | 423-426 | Species | denotes | HIV | Tax:12721 |
| 277 | 55-58 | Chemical | denotes | GBS | |
| 278 | 512-515 | Chemical | denotes | GBS | |
| 279 | 658-670 | Chemical | denotes | gangliosides | MESH:D005732 |
| 280 | 743-746 | Chemical | denotes | GBS | |
| 281 | 886-898 | Chemical | denotes | gangliosides | MESH:D005732 |
| 282 | 1426-1437 | Chemical | denotes | ganglioside | MESH:D005732 |
| 283 | 1843-1861 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 284 | 1863-1882 | Chemical | denotes | Lopinavir/Ritonavir | MESH:C558899 |
| 285 | 1888-1900 | Chemical | denotes | Azithromycin | MESH:D017963 |
| 286 | 1902-1905 | Chemical | denotes | GBS | |
| 287 | 2005-2008 | Chemical | denotes | GBS | |
| 288 | 114-123 | Disease | denotes | paralysis | MESH:D010243 |
| 289 | 136-161 | Disease | denotes | areflexia or hyporeflexia | MESH:D012021 |
| 290 | 275-311 | Disease | denotes | respiratory or intestinal infections | MESH:D012141 |
| 291 | 350-360 | Disease | denotes | infections | MESH:D007239 |
| 292 | 414-421 | Disease | denotes | rubella | MESH:D012409 |
| 293 | 435-446 | Disease | denotes | Hepatitis E | MESH:D016751 |
| 294 | 469-478 | Disease | denotes | pneumonia | MESH:D011014 |
| 295 | 603-622 | Disease | denotes | autoimmune disorder | MESH:D001327 |
| 296 | 763-771 | Disease | denotes | Covid-19 | MESH:C000657245 |
| 297 | 772-781 | Disease | denotes | infection | MESH:D007239 |
| 298 | 817-825 | Disease | denotes | Covid-19 | MESH:C000657245 |
| 299 | 1049-1070 | Disease | denotes | neurological symptoms | MESH:D009422 |
| 300 | 1105-1125 | Disease | denotes | respiratory symptoms | MESH:D012818 |
| 301 | 1158-1177 | Disease | denotes | lower-limb weakness | MESH:D018908 |
| 302 | 1211-1226 | Disease | denotes | facial diplegia | MESH:C531747 |
| 303 | 1239-1245 | Disease | denotes | ataxia | MESH:D001259 |
| 304 | 1276-1311 | Disease | denotes | flaccid tetraparesis or tetraplegia | MESH:D011782 |
| 305 | 1712-1725 | Disease | denotes | quadriparesis | MESH:D011782 |
| 306 | 1756-1761 | Disease | denotes | cough | MESH:D003371 |
| 307 | 1763-1768 | Disease | denotes | fever | MESH:D005334 |
| 308 | 1773-1780 | Disease | denotes | dyspnea | MESH:D004417 |
| 309 | 1782-1790 | Disease | denotes | Covid-19 | MESH:C000657245 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32535093-20890797-4828861 | 705-707 | 20890797 | denotes | 34 |
| 32535093-8634515-4828862 | 708-710 | 8634515 | denotes | 35 |
| 32535093-32246917-4828863 | 2145-2147 | 32246917 | denotes | 38 |