PMC:7289100 / 42884-43224 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T141","span":{"begin":200,"end":204},"obj":"Body_part"},{"id":"T142","span":{"begin":222,"end":230},"obj":"Body_part"},{"id":"T143","span":{"begin":258,"end":268},"obj":"Body_part"}],"attributes":[{"id":"A141","pred":"fma_id","subj":"T141","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A142","pred":"fma_id","subj":"T142","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T501","span":{"begin":24,"end":44},"obj":"Disease"},{"id":"T502","span":{"begin":35,"end":44},"obj":"Disease"},{"id":"T503","span":{"begin":49,"end":88},"obj":"Disease"},{"id":"T504","span":{"begin":249,"end":252},"obj":"Disease"},{"id":"T506","span":{"begin":258,"end":288},"obj":"Disease"},{"id":"T507","span":{"begin":290,"end":293},"obj":"Disease"},{"id":"T508","span":{"begin":295,"end":339},"obj":"Disease"},{"id":"T509","span":{"begin":305,"end":339},"obj":"Disease"}],"attributes":[{"id":"A501","pred":"mondo_id","subj":"T501","obj":"http://purl.obolibrary.org/obo/MONDO_0008383"},{"id":"A502","pred":"mondo_id","subj":"T502","obj":"http://purl.obolibrary.org/obo/MONDO_0005578"},{"id":"A503","pred":"mondo_id","subj":"T503","obj":"http://purl.obolibrary.org/obo/MONDO_0016168"},{"id":"A504","pred":"mondo_id","subj":"T504","obj":"http://purl.obolibrary.org/obo/MONDO_0007399"},{"id":"A505","pred":"mondo_id","subj":"T504","obj":"http://purl.obolibrary.org/obo/MONDO_0017361"},{"id":"A506","pred":"mondo_id","subj":"T506","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A507","pred":"mondo_id","subj":"T507","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A508","pred":"mondo_id","subj":"T508","obj":"http://purl.obolibrary.org/obo/MONDO_0015542"},{"id":"A509","pred":"mondo_id","subj":"T509","obj":"http://purl.obolibrary.org/obo/MONDO_0015540"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T327","span":{"begin":114,"end":119},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T328","span":{"begin":124,"end":125},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T329","span":{"begin":198,"end":204},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T330","span":{"begin":206,"end":209},"obj":"http://purl.obolibrary.org/obo/CLO_0002199"},{"id":"T331","span":{"begin":269,"end":279},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T191","span":{"begin":114,"end":119},"obj":"Chemical"},{"id":"T192","span":{"begin":181,"end":188},"obj":"Chemical"}],"attributes":[{"id":"A191","pred":"chebi_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/CHEBI_35209"},{"id":"A192","pred":"chebi_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T212","span":{"begin":24,"end":44},"obj":"Phenotype"},{"id":"T213","span":{"begin":222,"end":247},"obj":"Phenotype"}],"attributes":[{"id":"A212","pred":"hp_id","subj":"T212","obj":"http://purl.obolibrary.org/obo/HP_0001370"},{"id":"A213","pred":"hp_id","subj":"T213","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T21","span":{"begin":258,"end":279},"obj":"http://purl.obolibrary.org/obo/GO_0042116"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-sentences","denotations":[{"id":"T264","span":{"begin":0,"end":340},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T586","span":{"begin":181,"end":188},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T587","span":{"begin":198,"end":204},"obj":"CL:0000084"},{"id":"T588","span":{"begin":258,"end":268},"obj":"CL:0000235;GO:0042116"},{"id":"T589","span":{"begin":269,"end":279},"obj":"GO:0042116"},{"id":"T590","span":{"begin":305,"end":319},"obj":"GO:0030097"},{"id":"T56655","span":{"begin":181,"end":188},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T74988","span":{"begin":198,"end":204},"obj":"CL:0000084"},{"id":"T49496","span":{"begin":258,"end":268},"obj":"CL:0000235;GO:0042116"},{"id":"T53632","span":{"begin":269,"end":279},"obj":"GO:0042116"},{"id":"T14127","span":{"begin":305,"end":319},"obj":"GO:0030097"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1456","span":{"begin":24,"end":44},"obj":"Disease"},{"id":"1457","span":{"begin":249,"end":252},"obj":"Disease"},{"id":"1458","span":{"begin":258,"end":288},"obj":"Disease"},{"id":"1459","span":{"begin":320,"end":339},"obj":"Disease"}],"attributes":[{"id":"A1456","pred":"tao:has_database_id","subj":"1456","obj":"MESH:D001172"},{"id":"A1457","pred":"tao:has_database_id","subj":"1457","obj":"MESH:D003398"},{"id":"A1458","pred":"tao:has_database_id","subj":"1458","obj":"MESH:D055501"},{"id":"A1459","pred":"tao:has_database_id","subj":"1459","obj":"MESH:D051359"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"It is approved to treat rheumatoid arthritis and cryopyrin-associated periodic syndromes, and it is also used off-label for a variety of inflammatory conditions and severe chimeric antigen receptor T cell (CAR-T)-mediated cytokine release syndrome (CRS) and macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis."}