PMC:7283670 / 61047-62249
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T220 | 291-296 | Body_part | denotes | mouth | http://purl.org/sig/ont/fma/fma49184 |
T221 | 382-387 | Body_part | denotes | mouth | http://purl.org/sig/ont/fma/fma49184 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T142 | 291-296 | Body_part | denotes | mouth | http://purl.obolibrary.org/obo/UBERON_0000165 |
T143 | 382-387 | Body_part | denotes | mouth | http://purl.obolibrary.org/obo/UBERON_0000165 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T361 | 99-107 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T362 | 177-185 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T571 | 291-296 | http://www.ebi.ac.uk/efo/EFO_0000825 | denotes | mouth |
T572 | 324-330 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | Active |
T573 | 382-387 | http://www.ebi.ac.uk/efo/EFO_0000825 | denotes | mouth |
T574 | 526-530 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 3, 5 |
T575 | 543-545 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T576 | 589-593 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 3, 5 |
T577 | 606-608 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T578 | 1115-1119 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 4, 5 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T34447 | 14-33 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T27940 | 14-23 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T20411 | 24-33 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T71837 | 37-55 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T131 | 116-135 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T12779 | 116-125 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T42223 | 126-135 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T53502 | 143-161 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T77554 | 162-169 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
T82580 | 244-263 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T91739 | 244-253 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T7801 | 254-263 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T31954 | 343-361 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T56995 | 444-463 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T74129 | 444-453 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T14779 | 454-463 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T75588 | 468-486 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T41134 | 488-490 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T71387 | 711-717 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T58068 | 963-982 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T12331 | 963-972 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T50748 | 973-982 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T149 | 986-1004 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T150 | 1065-1084 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T151 | 1065-1074 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T152 | 1075-1084 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T153 | 1089-1107 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T154 | 1153-1161 | Chemical | denotes | medicine | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T633 | 0-323 | Sentence | denotes | Comparison of lopinavir/ritonavir or hydroxychloroquine in patients with mild coronavirus disease (COVID‐19) Drug: lopinavir/ritonavir, Drug: hydroxychloroquine sulfate Korea/COVID‐19 150, all, 16 years to 99 years Treatment Experimental: lopinavir/ritonavir 200 mg/100 mg 2 tablets by mouth, every 12 hr for 7–10 days |
T634 | 324-414 | Sentence | denotes | Active comparator: hydroxychloroquine 200 mg 2 tablets by mouth, every 12 hr for 7–10 days |
T635 | 415-546 | Sentence | denotes | No intervention: control, no lopinavir/ritonavir and hydroxychloroquine II Primary: viral load (hospital Day 3, 5, 7, 10, 14, 18) |
T636 | 547-1202 | Sentence | denotes | Secondary viral load change (hospital Day 3, 5, 7, 10, 14, 18), time to clinical improvement (time frame: up to 28 days), percentage of progression to supplemental oxygen requirement by Day 7, Time to NEWS2 (National Early Warning Score 2) of 3 or more maintained for 24 hr by Day 7, time to clinical failure, defined as the time to death, mechanical ventilation, or ICU admission (up to 28 days), rate of switch to lopinavir/ritonavir or hydroxychloroquine by Day 7, adverse effects (up to 28 days), concentration of lopinavir/ritonavir and hydroxychloroquine (1, 2, 4, 5, 12 hr after taking intervention medicine) NCT04307693/Recruiting, Mar11‐May 2020 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1887 | 59-67 | Species | denotes | patients | Tax:9606 |
2055 | 14-33 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
2056 | 116-135 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
2057 | 244-263 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
2058 | 444-463 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
2059 | 963-982 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
2060 | 1065-1084 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
2121 | 78-97 | Disease | denotes | coronavirus disease | MESH:D018352 |
2122 | 99-107 | Disease | denotes | COVID‐19 | MESH:C000657245 |
2123 | 177-185 | Disease | denotes | COVID‐19 | MESH:C000657245 |
2124 | 880-885 | Disease | denotes | death | MESH:D003643 |