PMC:7283670 / 23266-24169
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7283670","sourcedb":"PMC","sourceid":"7283670","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7283670","text":"Investigation on a familial cluster of five patients concluded that SARS‐CoV‐2 might have actually been transmitted by an asymptomatic carrier in the family (Bai et al., 2020). Surprisingly, the first reverse transcription polymerase chain reaction (RT‐PCR) test of the asymptomatic family member was reported negative; a noteworthy example of a false‐negative result. Unwanted false‐negative results are inevitably reported due to a number of factors, for example, quality of the test kit, sufficiency of the collected sample, or performance of the test by clinicians. To this date, RT‐PCR has widely been used as a reliable diagnostic method (Corman et al., 2020). Thus, her second RT‐PCR result, reported positive, was unlikely to have been a false‐positive result; hence, it was accepted as the definite evidence that the suspected person had indeed been infected with SARS‐CoV‐2 (Bai et al., 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