PMC:7283670 / 13361-14241 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T78439","span":{"begin":9,"end":14},"obj":"Body_part"},{"id":"T25717","span":{"begin":294,"end":299},"obj":"Body_part"},{"id":"T73445","span":{"begin":350,"end":359},"obj":"Body_part"},{"id":"T72041","span":{"begin":360,"end":365},"obj":"Body_part"},{"id":"T58247","span":{"begin":449,"end":458},"obj":"Body_part"},{"id":"T31815","span":{"begin":580,"end":585},"obj":"Body_part"},{"id":"T15072","span":{"begin":778,"end":783},"obj":"Body_part"},{"id":"T14190","span":{"begin":856,"end":861},"obj":"Body_part"}],"attributes":[{"id":"A19843","pred":"fma_id","subj":"T78439","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A97931","pred":"fma_id","subj":"T25717","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A24343","pred":"fma_id","subj":"T73445","obj":"http://purl.org/sig/ont/fma/fma9706"},{"id":"A52949","pred":"fma_id","subj":"T72041","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A64145","pred":"fma_id","subj":"T58247","obj":"http://purl.org/sig/ont/fma/fma9706"},{"id":"A39321","pred":"fma_id","subj":"T31815","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A23156","pred":"fma_id","subj":"T15072","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A8042","pred":"fma_id","subj":"T14190","obj":"http://purl.org/sig/ont/fma/fma7197"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T13","span":{"begin":9,"end":14},"obj":"Body_part"},{"id":"T14","span":{"begin":294,"end":299},"obj":"Body_part"},{"id":"T15","span":{"begin":350,"end":359},"obj":"Body_part"},{"id":"T16","span":{"begin":350,"end":354},"obj":"Body_part"},{"id":"T17","span":{"begin":355,"end":359},"obj":"Body_part"},{"id":"T18","span":{"begin":449,"end":458},"obj":"Body_part"},{"id":"T19","span":{"begin":449,"end":453},"obj":"Body_part"},{"id":"T20","span":{"begin":454,"end":458},"obj":"Body_part"},{"id":"T21","span":{"begin":580,"end":585},"obj":"Body_part"},{"id":"T22","span":{"begin":778,"end":783},"obj":"Body_part"},{"id":"T23","span":{"begin":856,"end":861},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0002394"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0001970"},{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0000058"},{"id":"A18","pred":"uberon_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/UBERON_0002394"},{"id":"A19","pred":"uberon_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/UBERON_0001970"},{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/UBERON_0000058"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T64","span":{"begin":79,"end":83},"obj":"Disease"},{"id":"T65","span":{"begin":90,"end":99},"obj":"Disease"},{"id":"T66","span":{"begin":164,"end":172},"obj":"Disease"},{"id":"T67","span":{"begin":337,"end":346},"obj":"Disease"},{"id":"T68","span":{"begin":371,"end":375},"obj":"Disease"},{"id":"T69","span":{"begin":502,"end":510},"obj":"Disease"},{"id":"T70","span":{"begin":819,"end":823},"obj":"Disease"},{"id":"T71","span":{"begin":830,"end":839},"obj":"Disease"}],"attributes":[{"id":"A64","pred":"mondo_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A65","pred":"mondo_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A66","pred":"mondo_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A67","pred":"mondo_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A68","pred":"mondo_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A69","pred":"mondo_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A70","pred":"mondo_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A71","pred":"mondo_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T20037","span":{"begin":9,"end":14},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T23913","span":{"begin":9,"end":14},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T51401","span":{"begin":24,"end":29},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T41552","span":{"begin":53,"end":54},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T51587","span":{"begin":260,"end":261},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T97632","span":{"begin":275,"end":278},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T65016","span":{"begin":294,"end":299},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T10091","span":{"begin":294,"end":299},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T93522","span":{"begin":350,"end":359},"obj":"http://purl.obolibrary.org/obo/UBERON_0002394"},{"id":"T2425","span":{"begin":360,"end":365},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T14278","span":{"begin":400,"end":420},"obj":"http://purl.obolibrary.org/obo/PR_000023540"},{"id":"T40828","span":{"begin":449,"end":458},"obj":"http://purl.obolibrary.org/obo/UBERON_0002394"},{"id":"T25173","span":{"begin":580,"end":585},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T60607","span":{"begin":580,"end":585},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T43711","span":{"begin":736,"end":744},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T50046","span":{"begin":778,"end":783},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T12394","span":{"begin":778,"end":783},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T44962","span":{"begin":856,"end":861},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T50968","span":{"begin":856,"end":861},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T21","span":{"begin":843,"end":847},"obj":"Chemical"}],"attributes":[{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T50590","span":{"begin":409,"end":420},"obj":"http://purl.obolibrary.org/obo/GO_0016791"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T104","span":{"begin":0,"end":259},"obj":"Sentence"},{"id":"T105","span":{"begin":260,"end":382},"obj":"Sentence"},{"id":"T106","span":{"begin":383,"end":562},"obj":"Sentence"},{"id":"T107","span":{"begin":563,"end":648},"obj":"Sentence"},{"id":"T108","span":{"begin":649,"end":880},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T14","span":{"begin":697,"end":706},"obj":"Phenotype"}],"attributes":[{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0001397"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"264","span":{"begin":65,"end":73},"obj":"Species"},{"id":"265","span":{"begin":199,"end":207},"obj":"Species"},{"id":"266","span":{"begin":371,"end":381},"obj":"Species"},{"id":"267","span":{"begin":488,"end":496},"obj":"Species"},{"id":"268","span":{"begin":754,"end":762},"obj":"Species"},{"id":"269","span":{"begin":79,"end":99},"obj":"Disease"},{"id":"270","span":{"begin":112,"end":126},"obj":"Disease"},{"id":"271","span":{"begin":164,"end":172},"obj":"Disease"},{"id":"272","span":{"begin":337,"end":346},"obj":"Disease"},{"id":"273","span":{"begin":449,"end":465},"obj":"Disease"},{"id":"274","span":{"begin":502,"end":510},"obj":"Disease"},{"id":"275","span":{"begin":683,"end":706},"obj":"Disease"},{"id":"276","span":{"begin":778,"end":790},"obj":"Disease"},{"id":"277","span":{"begin":819,"end":839},"obj":"Disease"}],"attributes":[{"id":"A264","pred":"tao:has_database_id","subj":"264","obj":"Tax:9606"},{"id":"A265","pred":"tao:has_database_id","subj":"265","obj":"Tax:9606"},{"id":"A266","pred":"tao:has_database_id","subj":"266","obj":"Tax:2697049"},{"id":"A267","pred":"tao:has_database_id","subj":"267","obj":"Tax:9606"},{"id":"A268","pred":"tao:has_database_id","subj":"268","obj":"Tax:9606"},{"id":"A269","pred":"tao:has_database_id","subj":"269","obj":"MESH:C000657245"},{"id":"A270","pred":"tao:has_database_id","subj":"270","obj":"MESH:D056486"},{"id":"A271","pred":"tao:has_database_id","subj":"271","obj":"MESH:C000657245"},{"id":"A272","pred":"tao:has_database_id","subj":"272","obj":"MESH:D007239"},{"id":"A273","pred":"tao:has_database_id","subj":"273","obj":"MESH:D001649"},{"id":"A274","pred":"tao:has_database_id","subj":"274","obj":"MESH:C000657245"},{"id":"A275","pred":"tao:has_database_id","subj":"275","obj":"MESH:D005234"},{"id":"A276","pred":"tao:has_database_id","subj":"276","obj":"MESH:D056486"},{"id":"A277","pred":"tao:has_database_id","subj":"277","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Impaired liver function tests have been reported for a number of patients with SARS‐CoV‐2 infection, suggesting hepatic damage as an extrapulmonary complication of COVID‐19 in almost one half of the patients (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). A recent study has concluded that liver function abnormality might stem from infection of bile duct cells with SARS‐CoV‐2. Nonetheless, the alkaline phosphatase value, which is an index of bile duct damage, were not specific in patients with COVID‐19 (Chen, Zhou, et al., 2020; Wang, Hu, et al., 2020). Investigation of liver biopsy specimens was accompanied by new pathological findings. Scientists have reported moderate microvascular steatosis, and mild lobular and portal activity in these patients, that suggests liver damage may have arisen from either SARS‐CoV‐2 infection or drug‐induced liver (Xu et al., 2020)."}