
PMC:7283670 / 125274-126251
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T92 | 31-34 | Body_part | denotes | arm | http://purl.org/sig/ont/fma/fma24890 |
T93 | 47-51 | Body_part | denotes | axis | http://purl.org/sig/ont/fma/fma12520 |
T94 | 261-267 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
T95 | 941-947 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T234 | 31-34 | Body_part | denotes | arm | http://purl.obolibrary.org/obo/UBERON_0001460 |
T235 | 941-947 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T681 | 201-213 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T682 | 317-326 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T683 | 433-442 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T684 | 447-472 | Disease | denotes | acute respiratory failure | http://purl.obolibrary.org/obo/MONDO_0001208|http://purl.obolibrary.org/obo/MONDO_0021113 |
T686 | 494-498 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T687 | 754-762 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T172 | 8-9 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T173 | 31-34 | http://www.ebi.ac.uk/efo/EFO_0001410 | denotes | arm |
T174 | 59-60 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T175 | 261-267 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
T176 | 347-353 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T265 | 79-93 | Chemical | denotes | Angiotensin II | http://purl.obolibrary.org/obo/CHEBI_2719 |
T266 | 91-93 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T267 | 94-105 | Chemical | denotes | Angiotensin | http://purl.obolibrary.org/obo/CHEBI_2719 |
T2111 | 139-150 | Chemical | denotes | Angiotensin | http://purl.obolibrary.org/obo/CHEBI_2719 |
T13587 | 243-257 | Chemical | denotes | Angiotensin II | http://purl.obolibrary.org/obo/CHEBI_2719 |
T82878 | 255-257 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T77587 | 397-407 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T42101 | 588-599 | Chemical | denotes | Angiotensin | http://purl.obolibrary.org/obo/CHEBI_2719 |
T86413 | 673-683 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T19 | 201-213 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T20 | 810-821 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
T21 | 838-849 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
T22 | 894-915 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1039 | 0-214 | Sentence | denotes | ACE2 is a prominent regulatory arm in the RAAS axis, thus, a disruption in ACE‐Angiotensin II‐Angiotensin Type 1 Receptor (AT1R), and ACE2/Angiotensin‐(1‐7)/Mas Receptor axes can result in multisystem inflammation. |
T1040 | 215-327 | Sentence | denotes | Increased levels of ACE and Angiotensin II in plasma are considered poor prognostic factors in severe pneumonia. |
T1041 | 328-473 | Sentence | denotes | Several studies on animal models have reported effectiveness of RAAS inhibitors in alleviation of severe pneumonia and acute respiratory failure. |
T1042 | 474-627 | Sentence | denotes | In the aftermath of SARS‐CoV‐2 and ACE2 binding, the enzyme is eventually degraded, hence, the inhibition of ACE2/Angiotensin‐(1‐7)/Mas Receptor pathway. |
T1043 | 628-822 | Sentence | denotes | Accordingly, it is assumed that ACE and AT1R inhibitors might be game‐changing agents that can especially be administered for COVID‐19 patients who have serious impairments in their homeostasis. |
T1044 | 823-977 | Sentence | denotes | Maintenance of homeostasis may ultimately result in suppression of the inflammatory response, mostly in the pulmonary tissue (Sun, Yang, Sun, & Su, 2020). |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T320 | 317-326 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T321 | 433-442 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T322 | 453-472 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
2592 | 0-4 | Gene | denotes | ACE2 | Gene:59272 |
2593 | 75-78 | Gene | denotes | ACE | Gene:1636 |
2594 | 123-127 | Gene | denotes | AT1R | Gene:185 |
2595 | 134-138 | Gene | denotes | ACE2 | Gene:59272 |
2596 | 235-238 | Gene | denotes | ACE | Gene:1636 |
2597 | 243-257 | Gene | denotes | Angiotensin II | Gene:183 |
2598 | 509-513 | Gene | denotes | ACE2 | Gene:59272 |
2599 | 583-587 | Gene | denotes | ACE2 | Gene:59272 |
2600 | 660-663 | Gene | denotes | ACE | Gene:1636 |
2601 | 668-672 | Gene | denotes | AT1R | Gene:185 |
2602 | 494-504 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
2603 | 763-771 | Species | denotes | patients | Tax:9606 |
2604 | 201-213 | Disease | denotes | inflammation | MESH:D007249 |
2605 | 317-326 | Disease | denotes | pneumonia | MESH:D011014 |
2606 | 433-442 | Disease | denotes | pneumonia | MESH:D011014 |
2607 | 453-472 | Disease | denotes | respiratory failure | MESH:D012131 |
2608 | 754-762 | Disease | denotes | COVID‐19 | MESH:C000657245 |
2609 | 789-800 | Disease | denotes | impairments | MESH:D060825 |