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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7281900","sourcedb":"PMC","sourceid":"7281900","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7281900","text":"Tuberous sclerosis complex (TSC) is a neurodevelopmental disorder with frequent occurrence of epilepsy, autism spectrum disorder (ASD), intellectual disability (ID), and tumors in multiple organs. The aberrant activation of mTORC1 in TSC has led to treatment with mTORC1 inhibitor rapamycin as a lifelong therapy for tumors, but TSC-associated neurocognitive manifestations remain unaffected by rapamycin.","tracks":[]}