PMC:7281546 / 54135-54448 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T329","span":{"begin":114,"end":121},"obj":"Body_part"}],"attributes":[{"id":"A329","pred":"fma_id","subj":"T329","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T119","span":{"begin":234,"end":237},"obj":"Disease"}],"attributes":[{"id":"A119","pred":"mondo_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/MONDO_0010565"}],"text":"For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T506","span":{"begin":244,"end":245},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T507","span":{"begin":275,"end":276},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T508","span":{"begin":302,"end":312},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T77304","span":{"begin":114,"end":121},"obj":"Chemical"}],"attributes":[{"id":"A85411","pred":"chebi_id","subj":"T77304","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T418","span":{"begin":146,"end":150},"obj":"http://purl.obolibrary.org/obo/GO_0008384"},{"id":"T419","span":{"begin":187,"end":191},"obj":"http://purl.obolibrary.org/obo/GO_0008384"},{"id":"T420","span":{"begin":219,"end":230},"obj":"http://purl.obolibrary.org/obo/GO_0009056"},{"id":"T421","span":{"begin":278,"end":293},"obj":"http://purl.obolibrary.org/obo/GO_0016310"}],"text":"For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation."}

{"project":"LitCovid-sentences","denotations":[{"id":"T414","span":{"begin":0,"end":313},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2494","span":{"begin":21,"end":25},"obj":"Gene"},{"id":"2495","span":{"begin":64,"end":69},"obj":"Gene"},{"id":"2496","span":{"begin":76,"end":80},"obj":"Gene"},{"id":"2497","span":{"begin":101,"end":105},"obj":"Gene"},{"id":"2498","span":{"begin":146,"end":150},"obj":"Gene"},{"id":"2499","span":{"begin":187,"end":191},"obj":"Gene"},{"id":"2500","span":{"begin":196,"end":200},"obj":"Gene"},{"id":"2501","span":{"begin":207,"end":211},"obj":"Gene"},{"id":"2502","span":{"begin":234,"end":237},"obj":"Gene"},{"id":"2503","span":{"begin":242,"end":246},"obj":"Gene"},{"id":"2504","span":{"begin":273,"end":277},"obj":"Gene"},{"id":"2505","span":{"begin":298,"end":301},"obj":"Gene"},{"id":"2513","span":{"begin":16,"end":20},"obj":"Species"},{"id":"2514","span":{"begin":71,"end":75},"obj":"Species"},{"id":"2515","span":{"begin":107,"end":111},"obj":"Species"},{"id":"2516","span":{"begin":202,"end":206},"obj":"Species"}],"attributes":[{"id":"A2494","pred":"tao:has_database_id","subj":"2494","obj":"Gene:5355"},{"id":"A2495","pred":"tao:has_database_id","subj":"2495","obj":"Gene:23586"},{"id":"A2496","pred":"tao:has_database_id","subj":"2496","obj":"Gene:92521"},{"id":"A2497","pred":"tao:has_database_id","subj":"2497","obj":"Gene:8517"},{"id":"A2498","pred":"tao:has_database_id","subj":"2498","obj":"Gene:29110"},{"id":"A2499","pred":"tao:has_database_id","subj":"2499","obj":"Gene:29110"},{"id":"A2500","pred":"tao:has_database_id","subj":"2500","obj":"Gene:3661"},{"id":"A2501","pred":"tao:has_database_id","subj":"2501","obj":"Gene:10045"},{"id":"A2502","pred":"tao:has_database_id","subj":"2502","obj":"Gene:1387"},{"id":"A2503","pred":"tao:has_database_id","subj":"2503","obj":"Gene:4792"},{"id":"A2504","pred":"tao:has_database_id","subj":"2504","obj":"Gene:4792"},{"id":"A2505","pred":"tao:has_database_id","subj":"2505","obj":"Gene:5970"},{"id":"A2513","pred":"tao:has_database_id","subj":"2513","obj":"Tax:28295"},{"id":"A2514","pred":"tao:has_database_id","subj":"2514","obj":"Tax:28295"},{"id":"A2515","pred":"tao:has_database_id","subj":"2515","obj":"Tax:28295"},{"id":"A2516","pred":"tao:has_database_id","subj":"2516","obj":"Tax:28295"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"For type I IFN, PEDV PLP2 removes ubiquitinated conjugates from RIG-I; PEDV nsp5 induces cleavage of NEMO; PEDV N protein directly interacts with TBK1 to obstruct the association between TBK1 and IRF3; PEDV nsp1 causes degradation of CBP and IκBα, as well as inhibition of IκBα phosphorylation and p65 activation."}